1. A method of computer generating production a strategy suitable for the exploitation of a reservoir of hydrocarbon in a natural environment and exploiting said reservoir, wherein said natural environment is limited in its surface by a domain (Ω), said method comprising: determining a reference system in the domain (Ω); determining an opportunity index OI as a function defined in the domain (Ω) providing the local production potential as a function of the location and the local properties; determining a radius of drainage rd providing the radius of drainage of the hydrocarbon at the end of life of a production well as a function of the opportunity index rd=rd(OI); identifying production behavior zone cluster or clusters (C1, C2) as locations with similar local production behavior; for each cluster (C1, C2) to be exploited: determining a representative value of the opportunity index OI (OI1, OI2) and its corresponding radius of drainage rd=rd(OI), (rd1, rd2), providing an angle α (α1, α2), generating a discretization of the cluster according to a grid with a regular pattern wherein the distance between the closest nodes of the pattern is 2*rd, and the orientation of the grid, selecting a reference line in the grid, in the reference system is the angle α, and determining the production well locations (P1, P2) in the cluster (C1, C2) as the coordinates of the nodes of the grid located within the cluster (C1, C2); and drilling wells at determined said production well locations (P1, P2).