1. A system for predicting a dose distribution, the system comprising: a first computing device comprising: a user input device operable to receive user input corresponding to a user selection of a selected dose prediction model from a plurality of dose prediction models; and a processor operable to generate at least one optimization objective based on the selected dose prediction model, and to predict at least one dose parameter for a radiation plan based on the at least one optimization objective, wherein the first computing device is comprised in a network of communicatively coupled computing devices.