1. A method for determining a time to aortic valve closure, comprising: receiving data corresponding to an imaged region of a left ventricle of a heart; identifying a plurality of points within the data; determining a peak negative strain for each of the points, the peak negative strain comprising a maximum contraction value and a time from onset to maximum contraction value; determining a weight value for each of the points based on the peak negative strain; and determining a time to aortic valve closure based on the weight value and the time from onset to maximum contraction value for each of the points.