1. A method for establishing, within pre-established limits of a desired value, tablet-to-tablet and batch-to-batch consistency of a particular physio-chemical parameter of a tabletted formulation, said parameter being release rate of drug substance relative to desired biological response and having a dependency on tablet hardness, said formulation being particulate material intended to be compacted into tablets on a suitable tablet press, comprising: (a) preliminarily compressing on the tablet press from a first batch of said formulation at least one tablet of the formulation at each of a plurality of different selected tabletting compression forces and obtaining from the tabletting events of said at least one tablets respective electrical signals representative of tablet formation force information and including maximum compression force information; (b) isolating from said tablet formation force information the maximum compression force information associated to each preliminarily compressed tablet; (c) analyzing at least one tablet preliminarily compressed at each of the selected compression forces to derive the respective values of the physio-chemical parameter thereof and relating said values of the parameter respectively to the corresponding maximum compression force of those tablets analyzed; (d) selecting from said values of the physio-chemical parameter a value within said pre-established limits which approximates the desired value of said parameter; (e) setting the tablet press at that compression force setting which corresponds to the selected value of said physio-chemical parameter and compressing the remainder of the first batch of the formulation at that setting of the tablet press; and (f) performing (a) - (e) for a second batch of the formulation, the maximum compression force setting of the tablet press selected thereby for said second batch which corresponds to said parameter of the tablets compacted from the second batch being within said pre-established limits and approximating that of the tablets compacted from the first batch.