1. A method for providing an assessment for disease status of a disease, comprising the steps of: a) constructing a computational, three-dimensional model of an organ representative of said disease status of a disease based on data for the organ, wherein the organ data includes image data of the organ, and the three-dimensional model includes a fluid-structure interaction and multiple components of the organ; b) computationally obtaining a certain mechanical distribution using the three-dimensional organ model; and c) computationally applying quantitative analysis of the mechanical distribution to provide an assessment for disease status of a disease.