1. A system for managing a therapy provided to a patient, comprising: a medication delivery device configured for two-way communication with at least one of a monitoring device and an institutional information system, wherein the medication delivery device adjusts the delivery of a drug, medication or fluid to a patient based on institutionally determined rules related to patient specific information; and a processor configured to provide an alert when the delivery of the drug, medication or fluid violates one of the institutionally determined rules, and configured to increase a priority of the alert when a status of the alert has not changed for a selected period of time.