1. A method for stimulating a suck central pattern generator and a trigeminal nerve in a brain of a human subject, such stimulation influencing brain response or brain development including repair of the brain, control of respiration, control of a non-nutritive suck pattern, mastication, and combinations thereof, the method comprising: contacting the human subject with an appliance to stimulate one or more nerve ending near the subject's mouth, including the facial region proximal to at least one lip and a tongue; and, actuating the appliance in response to a signal to generate a mechanical transfer of energy in at least one burst as an impulse sufficient to be recognized as a tactile stimulus by the subject's suck central pattern generator; wherein each burst comprises at least two square wave pulses of the same amplitude with the pulse period increasing with each successive pulse to form a decelerating pulse train sequence; and, wherein the square wave pulses range in frequency between 1.5 Hz and 5 Hz.