1. A computer process for controlling at least one digital therapy system including a plurality of digital therapy applications; an electronic health system operable to provide patient health information associated with a patient to one or more health care providers; and a mobile device including at least at least one user interface, one or more computer readable media, at least one wireless communication unit, and at least one computer processor device operably coupled to the one or more computer readable media, the computer process including operations comprising: outputting via the at least one user interface at least one indication to administer at least one medication to treat at least one medical issue of a patient; outputting via the at least one user interface at least one indication to implement at least one digital therapy application of the at least one digital therapy system in combination with the at least one medication in treatment of the at least one medical issue of the patient; monitoring for one or more reactions associated with the patient in response to combination therapy involving the at least one medication and the at least one digital therapy application; modifying at least one element of the at least one digital therapy application at least partly based on one or more reactions of the patient detected in response to combination therapy involving the at least one medication and the at least one digital therapy application; and transmitting via the at least one wireless communication unit reporting information associated with one or more reactions of the patient for output via the electronic health system.