1. A method for improving reliability and availability of an information handling system, the method comprising: capturing operational data associated with an operating margin; identifying a threshold specified by a user pre-defined profile, wherein the user pre-defined profile is useable in adjusting the operating margin, wherein the user pre-defined profile is included in a policy that at least partially controls a subsystem of the information handling system; wherein the operating margin includes a thermal margin, a frequency margin, a voltage margin, a timing margin, and at least one of a memory cell retention margin, an error rate margin, and a signal integrity margin; comparing the captured operational data to the user pre-defined threshold; identifying a parameter specified by the user pre-defined profile; and modifying the operation of a component of the subsystem of the information handling system based, at least in part, on the identified parameter specified by the user pre-defined profile, wherein the modification results in adjusting the operating margin.