1. A method of operating a clinical monitoring device, the method comprising: (a) collecting in the clinical monitoring device a first health data set from a subject or clinician during a first time range and a second health data set from the subject or the clinician during a second time range, at least one of the second health data set and the second time range being determined in part based on a content of the first health data set, wherein the first and second time ranges are part of a protocol, wherein the protocol is based on a trial; (b) recording the first and second health data sets in the clinical monitoring device; (c) including a time and date with the recorded health data sets; and (d) initiating a time shifting mode that allows a user of the clinical monitoring device to adjust an operating date and time of the clinical monitoring device from a first event in the protocol, corresponding to a first operational state of the clinical monitoring device, relative to a second event in the protocol, corresponding to a second operational state of the clinical monitoring device, the clinical monitoring device operating at the second event in the protocol in the same manner and collecting health data from the subject or clinician in the same manner as if the clinical monitoring device had reached the second event without intervention by the user and resulting in initiation of the second operational state of the clinical monitoring device, wherein adjustment of the operating date and time of the clinical monitoring device from the first event in the protocol to the second event in the protocol changes an operational state of the clinical monitoring device without modification to the trial.