1. An unmanned aerial vehicle, comprising: a frame; a propulsion system connected to the frame; a retaining system connected to the frame and configured to retain a package; a communication system connected to the frame and configured to receive gesture input; and a management module associated with at least the communication system and comprising: memory that stores computer-executable instructions; and at least one processor configured to access the memory and execute the computer-executable instructions to at least: access a delivery plan that identifies: the package; and a flight plan that includes a geographic location for delivery of the package; receive, via the communication system, a first gesture input comprising a first gesture by a first human user when the unmanned aerial vehicle is executing the flight plan; in response to receiving the first gesture input, access a portion of gesture information from a gesture database, gesture information from the gesture database describing a plurality of gestures capable of being recognized by the communication system; determine, based on the first gesture and the portion of gesture information, a trajectory adjustment for the unmanned aerial vehicle; instruct the propulsion system to implement the trajectory adjustment; receive a second gesture input comprising a second gesture by a second human user when the unmanned aerial vehicle is executing the flight plan; and instruct the retaining system to deliver the package at the physical location based in part on the second gesture input.