1. A method of processing a positron emission tomography (PET) imaging data set acquired of a subject, the method comprising: generating image content independently for each positron-electron annihilation event of a plurality of positron-electron annihilation events of the PET imaging data set based on time-of-flight (TOF) localization to form a generated image comprising an accumulation of the independently generated image content, wherein the generating comprises increasing values of image pixels or voxels of an image space by amounts corresponding to a TOF kernel representing the TOF localization such that the accumulation of value increases forms the generated image; wherein the generating operations are performed by a digital processor.