1. A computer program product for facial feature substitution in a video conference, the computer program product comprising: one or more computer readable storage devices and program instructions stored on the one or more computer readable storage devices, the program instructions executable by a processor, the program instructions comprising: program instructions to receive one or more pre-recorded videos of an attendee participating in a video conference, the one or more pre-recorded videos including at least one pre-recorded video of an attendee speaking; program instructions to determine an avatar for use in place of a live video feed of the attendee in the video conference; program instructions to determine one or more portions of the one or more pre-recorded videos of the attendee corresponding to at least one targeted facial feature of the attendee in the live video feed of the attendee participating in the video conference; and program instructions to substitute the one or more portions of the one or more pre-recorded videos into the avatar, the substitution corresponding to the at least one targeted facial feature of the attendee such that the avatar mimics the at least one targeted facial feature of the attendee in the video conference.