1. A method for non-invasive assessment of an arterial stenosis, comprising: segmenting a plurality of mesh candidates for an anatomical model of an artery including a stenosis region of a patient from medical imaging data; computing a hemodynamic index for the stenosis region in each of the plurality of mesh candidates; and determining whether a variation among values of the hemodynamic index for the stenosis region in each of the plurality of mesh candidates is significant with respect to a threshold associated with a clinical decision regarding the stenosis region.