1. A system comprising: a target structure comprising one or more fiducial features; an automated positioning platform coupled to the target structure and under control of one or more computing systems, the positioning platform configured to orient the target structure to a plurality of poses by moving in one or more degrees of freedom at least partly in response to receiving corresponding instructions from the one or computing systems; a camera configured to acquire one or more acquired images of the target structure in each of the plurality of poses; a calibration module configured to: determine an observed location of the one or more fiducial features within at least a portion of the one or more acquired images of the target structure in the plurality of poses; and generate calibration data associated with the camera based at least in part on the observed location of the one or more fiducial features in the acquired images.