1. A method of performing pan-oral imaging, said method comprising: generating a plurality of data points representative of spatial positions of an actual dentition of a patient with respect to a defined spatial coordinate system; computing a fitted curve through at least a portion of said spatial positions of said dentition using said plurality of data points; computing a pan-oral image acquisition trajectory with respect to said defined spatial coordinate system using said fitted curve; and acquiring a pan-oral image of said dentition along said pan-oral image acquisition trajectory.