1. A device for microscopy of a plurality of samples, comprising: a first optical detector, which is configured to consecutively adopt a plurality of measuring positions and to detect first image data of a sample with a first spatial resolution at each measuring position; an image data analyser device which is configured to determine for each sample a region of the sample to be examined represented within the respective first image data; a second optical detector, which is coupled to the first optical detector in such a manner that adopts consecutively a plurality of measuring positions, which the first optical detector had previously adopted and wherein the second optical detector is configured to capture for each sample second image data from the region to be examined of the respective sample with a second spatial resolution, which is higher than the first spatial resolution.