1. A system, for treating a target tissue of an eye with x-ray radiation, comprising: a radiation source configured to emit x-ray beams at the target tissue of the eye; an alignment system configured to align the x-ray beams with an axis traversing the target tissue and, based on an indication of a location of the target tissue, directs the x-ray beam to be emitted toward the target tissue; and a holder configured to stabilize the eye during emission of the x-ray beams and comprising a fiducial marker configured to provide the indication of the location of the target tissue.