1. A method for use in biology, histology, and pathology, comprising: providing a digital first image ( 44 ) of a first slice ( 12 ) of an object ( 10 ) comprising biological material; generating a digital second image ( 46 ) of a second slice ( 14 ) of the object; determining a region of interest ( 50 ) in the second image on the basis of a region of interest ( 48 ) in the first image; determining a region of interest in the second slice on the basis of the region of interest in the second image; and extracting material from the region of interest in the second slice.