1. A method of segmenting a surface in a multi-dimensional dataset comprising a plurality of images, said method comprising the steps of: selecting, by a processor, an image segmentation algorithm based on a deformable surface model comprising an a-priori constructed shape model and an a-priori constructed topology model, whereby the shape model includes first parameters and the topology model includes second parameters; accessing, by the processor, pre-determined shape parameters and topology parameters of the surface; adapting, by the processor, the first parameters and the second parameters based on the shape parameters and the topology parameters yielding adapted first parameters and adapted second parameters; segmenting, by the processor, the surface in the multi-dimensional dataset using said image segmentation algorithm with the adapted first parameters and the adapted second parameters yielding respective portions of the surface for each segmented image; tracking, by the processor, the surface in the multi-dimensional dataset to establish spatial correspondence between said surface portions.