1. A computer-implemented segmentation method for segmenting a digitized pathology image of tissue into at least two non-overlapping regions for use in disease diagnosis, the method comprising: generating a first initial data set comprising a segmentation of pixels in the digitized pathology image as belonging to a first region using a first method of processing; generating a second initial data set comprising a current best segmentation of pixels in the digitized pathology image as belonging to the first region using a second method of processing; iteratively determining a final first region data set based on the first and second initial data sets, wherein the final first region data set comprises a segmentation of pixels in the digitized pathology image as belonging to the first region; and segmenting the digitized pathology image into a first region and a remainder region based on the final first region data set, wherein the generating of the first and second initial data sets, the iteratively determining and the segmenting are performed by a processor.