1. A method of driving a display device, the method comprising: sub-sampling an original image signal; generating a sub-image signal; generating a sub-interpolated image signal from the sub-image signal; generating an interpolated image signal by realigning the sub-interpolated image signal; and displaying a display image based on the interpolated image signal, wherein the sub-sampling the original image signal and the generating the sub-interpolated image signal are performed by dividing the original image signal into even data and odd data, and wherein the even data and the odd data are inputted to different image interpolation chips of the k image interpolation chips to generate the sub-interpolated image signal.