1. A data retrieval system for retrieving data from a multidimensional medical data set, comprising: a client configured to electronically request image data of a patient; a server in communication with a plurality of electronically stored multidimensional patient medical image data sets; and an electronic data retrieval interface in communication with the client and the server, the data retrieval interface configured to retrieve image data from the multidimensional patient medical data sets, the respective data sets having a number of grid points in G dimensions, and a number of values V for each grid point, wherein some of the data sets have different G dimensions and V values than others, wherein the data retrieval interface is configured to employ a Physical region object that defines a multi-dimensional region extent associated with a client request for data on a region of interest to retrieve relevant image data from a respective patient data set, and wherein some of the data sets have grid points in G dimensions such that G≦4 and at least some have multivariate values for each grid point such that 1<V≦6 while others have a single value for a respective grid point such that V=1.