1. A medical evaluation system comprising: an input/output (I/O) module configured to receive sensory data obtained by a motion sensor disposed in a mobile device carried by a patient at least when the patient is in a non-clinical environment, wherein the sensory data represents motion of the patient; a processing module configured to extract medically relevant data from the sensory data received from the sensor in the mobile device, the relevant data including one or more features of interest in the sensory data; and an analysis module configured to derive one or more surrogate biomarkers from the relevant data, the surrogate biomarkers representative of at least one of a state of a medical condition or a progression of a medical condition of the patient.