1. A method of segmenting a structure in a dataset comprising a plurality of multi-dimensional images acquired for respective temporal phases in a temporal sequence, each multi-dimensional image comprising data on a target tissue and on a further tissue, said method comprising the steps of: accessing results of a binary segmentation of the temporally sequenced images yielding temporally sequenced binary coded images whereby image portions corresponding to the target tissue and to the further tissue are binary coded; for all temporal phases from the temporal sequence computing successive difference between pairs of successive binary coded images yielding a multi-dimensional temporal feature map comprising a plurality of discrete values; deriving spatial positions in the dataset corresponding to a predetermined discrete value selectable from said plurality of discrete values; accessing a pre-defined deformable shape model of the structure; segmenting the structure by deforming said shape model in accordance with said spatial positions.