1. A digital x-ray imaging system, comprising: an x-ray source adapted to emit an x-ray beam; a collimator to collimate the x-ray beam to an identified region of interest; a positioning system to translate or rotate the x-ray source from a first position to a second position, wherein the second position is different than the first position; a digital x-ray detector adapted to capture a first image of the region of interest when the x-ray source is in the first position, and capture a second image of the region of interest when the x-ray source is in the second position; a processing engine to extract features from each of the region of interest of the first and second captured images; and an analyzer analyzing the extracted features and generating an indicator of a disease responsive to the extracted features.