1. An imaging system, comprising: a cryomicrotome having a microtome chamber configured to house a sample, the cryomicrotome being configured to produce a slice from the sample; an episcopic imaging device configured to acquire an episcopic image of the sample while it is housed in the microtome chamber; a second imaging device configured to acquire a second non-episcopic image of one or more of, the sample, and the slice; and a register logic configured to register the episcopic image with the second non-episcopic image, the second imaging device being one of, a histological imaging device configured to acquire a histological image, an autoradiographic imaging device configured to acquire an autoradiographic image, a mass spectrometry imaging device configured to acquire a mass spectrometric image, a Raman spectroscopy device configured to acquire a Raman spectroscopic image, and a Fourier transform infrared spectroscopy (FTIR) device configured to acquire an FTIR image.