1. A method for adjusting an angiographic roadmapping mask, comprising: obtaining an original roadmapping mask of a targeted patient tissue region; obtaining a live fluoroscopic image of at least a portion of the targeted patient tissue region using an x-ray source and an x-ray detector; adjusting the roadmapping mask to match the live fluoroscopic image; and combining the adjusted roadmapping mask and the live fluoroscopic image to provide a displayed superimposed image to a user.