1. A computer-implemented method of registering information associated with a first data set of an anatomical structure to a second data set of the anatomical structure, the method comprising the steps: collecting the first data set of the anatomical structure with an imaging device; developing additional information for the first data set, wherein the additional information has a unique identifiable spatial relationship to the anatomical structure of the first data set; establishing a first arbitrary reference frame for the first data set, wherein the first arbitrary reference frame is established without reference to any pre-selected landmark on the anatomical structure and the first arbitrary reference frame has a unique spatial relationship to the first data set; collecting the second data set of the anatomical structure with the imaging device; establishing a second arbitrary reference frame for the second data set; transforming the first arbitrary reference frame to the second arbitrary reference frame by matching a unique spatial parameter of the first data set with the same unique spatial parameter of the second data set; and registering the additional information with the second data set.