1. A method for imaging a subject, comprising: acquiring preliminary image data corresponding to a first field of view of the subject at a first resolution using an imaging system comprising one or more radiation sources and a single hybrid detector responsive to radiation received from the one or more radiation sources, wherein the preliminary image data is acquired using at least one section of the hybrid detector comprising one or more detector elements having the first resolution and a first size, wherein the hybrid detector further comprises at least another section comprising one or more detector elements having a second resolution and a second size such that the detector elements having the second size are smaller than the detector elements having the first size; identifying a target region of interest based on the preliminary image data; positioning the subject so as to align the target region of interest along a designated axis; configuring one or more parameters associated with the radiation sources, the hybrid detector, a gantry associated with the imaging system, or combinations thereof, wherein configuring the one or more parameters comprises: operating in a multi-energy mode for the second resolution, wherein the multi-energy mode comprises switching tube voltage of the one or more radiation sources between one or more voltages; selectively focusing on the section of the hybrid detector comprising one or more detector elements having the second resolution and the second size for acquiring target image data corresponding to the target region of interest at the second resolution using a target focal spot size, wherein the target focal spot size is smaller than a preliminary focal spot size used for acquiring the preliminary image data at the first resolution; selectively switching the detector elements having the first size to a low resolution operating mode via a switching interface for acquiring the preliminary image data at the first resolution and selectively switching the detector elements having the second size to a high resolution operating mode via the switching interface for acquiring the target image data at the second resolution, wherein the second resolution is greater than the first resolution; and reconstructing one or more images corresponding to at least the target region of interest using the target image data, the preliminary image data, or a combination thereof, wherein the combination of operating in the multi-energy mode, selectively focusing on the target focal spot size, and selectively switching to the high resolution operating mode is configured to reduce dosage administered to the subject.