1. A non-retro-reflective imaging system comprising: foreoptics configured to receive and focus incident electromagnetic radiation to provide a source image having an image volume; a segmented relay optic configured to receive the source image and to reimage the source image onto a tilted image plane that is tilted so as to be non-perpendicular with respect to an optical axis of the imaging system, the segmented relay optic further configured to slice the image volume into a plurality of image slices and spatially position the plurality of image slices such that a depth of focus of each image slice overlaps the tilted image plane; and an image sensor co-aligned with the tilted image plane and configured to produce a reconstructed and substantially in-focus image from the plurality of image slices; wherein a tilt angle of the tilted image plane with respect to the optical axis of the imaging system exceeds an angle of acceptance of the foreoptics, thereby preventing retro-reflection of the incident electromagnetic radiation.