1. A method of acquiring and displaying breast tissue images, comprising: acquiring x-ray image data of a patient's breast, the x-ray image data comprising projection images taken at different angles of an origin of imaging x-rays relative to the patient's breast; generating tomosynthesis image data from the acquired x-ray image data, the tomosynthesis image data comprising a plurality of image slices of the patient's breast, each image slice having an orientation and a thickness; identifying an image slice of interest in the tomosynthesis image data, the identified image slice of interest depicting an object of interest; and displaying an image stack guide on a user interface, the image stack guide comprising a linear display object having a plurality of marks, each mark of the plurality associated with a respective image slice of the plurality of image slices, such that a user can navigate through the plurality of image slices using the linear display object, and an indicator disposed adjacent a respective mark on the linear display object associated with the identified image slice of interest.