1. A method for generating a patient specific four-dimensional (4D) multi-scale anatomical heart model having morphological, dynamics, and hemodynamics model components, comprising: generating a patient specific 4D geometric model estimated from a sequence of volumetric cardiac imaging data of a patient generated using at least one medical imaging modality; generating a patient specific 4D computational model based on one or more of personalized geometry, material properties, fluid boundary conditions, and flow velocity measurements in the 4D geometric model; and generating a patient specific biomechanical model based on Fluid Structure Interaction (FSI) simulations using the 4D computational model.