1. A computed tomography imaging process, including: accessing projection data representing two-dimensional projection images of an object acquired using a misaligned tomographic imaging apparatus; and processing the projection data to generate misalignment data representing one or more values that quantify respective misalignments of the tomographic imaging apparatus, wherein processing of the projection data includes processing the projection data to generate trial reconstructed tomographic cross-sectional images for each of a plurality of different slices of the corresponding tomogram.