1. A method of reducing fatigue resulting from viewing a three-dimensional (3D) image display, the method comprising: obtaining, from a meta box of a 3D image data stream, low visual fatigue parameter information with respect to a frame section comprising at least one frame of a received 3D image; obtaining disparity vector information with respect to disparity vectors of each frame of the 3D image; determining a disparity minimum limit value and a disparity maximum limit value with respect to the 3D image in a pixel size value of a display device based on at least one of a horizontal size and a vertical size of the display device and a resolution of the display device; and comparing the disparity minimum limit value and the disparity maximum limit value with the obtained disparity vector information and adjusting a disparity of the 3D image in the pixel size value of the display device, wherein the 3D image data stream is in an International Standard Organization (ISO)-based media file format, and the ISO-based media file format comprises a moov box, an mdat box, and the meta box.