1. An image composition system comprising: an acquisition engine configured to retrieve a first sub-image and a second sub-image; the first sub-image corresponding to a first set of 3D volume data, and the second sub-image corresponding to a second set of 3D volume data; an image processing engine configured to perform operations comprising retrieving a first overlapping image from the first sub-image; retrieving a second overlapping image from the second sub-image; generating a first 2D projection image and a first pixel map based on maximum intensity projection of the first overlapping image onto a plane; generating a second 2D projection image and a second pixel map based on maximum intensity projection of the second overlapping image onto the plane; performing 2D registration based on the first 2D projection image, the first pixel map, the second 2D projection image, and the second pixel map; performing 3D registration based on the 2D registration, the first pixel map, or the second pixel map; identifying a correlation between of the first sub-image including the first overlapping image and the second sub-image including the second overlapping image based on the 2D registration or the 3D registration; and fusing the first overlapping image and the second overlapping image based on the correlation to provide a composite image.