1. A method of segmenting a surface in a multi-dimensional dataset comprising a plurality of images, said method comprising the steps of: selecting an image segmentation algorithm based on a deformable surface model comprising an a-priori constructed shape model and an a-priori constructed topology model, whereby the shape model includes first parameters and the topology model includes second parameters; accessing pre-determined shape parameters and topology parameters of the surface; adapting the first parameters and the second parameters based on the shape parameters and the topology parameters yielding adapted first parameters and adapted second parameters; segmenting the surface in the multi-dimensional dataset using said image segmentation algorithm with the adapted first parameters and the adapted second parameters yielding respective portions of the surface for each segmented image; tracking the surface in the multi-dimensional dataset to establish spatial correspondence between said surface portions.