1. A system for correcting the color of transmission microscope images for different illuminants, comprising: a sample; a microscope having: a configurable numerical aperture having a plurality of pre-set positions, an optical train having a distal end and a proximal end and configured to convey illumination, an illumination source configured to direct illumination into the distal end of the optical train, and a selectable end piece positioned at the proximal end of the optical train, wherein the end piece is configured to direct the illumination to one of an image recording device or a removable light spectrum sensing device; a microscope slide having: an integral transmission filter array of known color spectra for each position of the numerical aperture and selectively disposed between the illumination source and the optical train; an image recording device, configured to record a plurality of images of the slide and the integral color filter array, wherein a raw image is comprised of a pixel array, each pixel having a color value; an image processor, configured by code executing therein, to: select a destination illumination; calculate the tristimulus values of the color filter array; obtain the raw image from the image recording device of the slide sample and color filter array; extract the RGB pixel values of the color filter array from the raw image; create a mapping matrix of the RGB pixel values to the tristimulus values; generate tristimulus values of a composite image by applying the mapping matrix to the RGB pixel values of the raw image; whereby the color of the microscope images is corrected without user intervention.