1. A vision system comprising: an image processor; and a swappable camera including a camera housing and an optical arrangement, the optical arrangement comprising a sensor array, the sensor array electronically coupled to the image processor, the swappable camera including an alignment indicator storing alignment data representative of an array-housing alignment of the sensor array relative to the camera housing, the image processor determines a region of interest of the sensor array using the alignment data, the image processor determines the region of interest by a process that includes maximizing a size of the region of interest within the sensor array to overlap with a concentric region of a desired sensor array position, and the image processor acquires an image of an image target using an auto-aligned mode wherein the image is acquired using only pixels located within the region of interest of the sensor array.