1. A method of aligning multiple images of a scene: receiving a reference image and an image-to-be-aligned: transforming said reference image into a transformed reference image comprising radiance factor grayscale pixel data; transforming said image-to-be-aligned into a transformed image-to-be-aligned comprising radiance factor grayscale pixel data. aligning said transformed reference image and said transformed image-to-be-aligned, comprising: applying random sample consensus to said transformed reference image and said transformed image-to-be-aligned to estimate a geometric transformation to derive a coarsely-aligned image from said transformed image-to-be-aligned; and applying diffeomorphic registration to derive a finely-aligned image from said coarsely-aligned image.