1. An image pickup system, comprising: a first sensor detecting a variation in inclination of an image pickup device to generate a first sensing data; a second sensor detecting a position movement from an image sensor in the image pickup device to generate a second sensing data; a driving unit coupled to the image sensor; and a processing module receiving the first and second sensing data, integrating the first sensing data, calculating the integrated first sensing data and the second sensing data to obtain control information, and enabling the driving unit to adjust the position of the image sensor according to the control information.