1. An image processing system, comprising: a module for importing a plurality of ocular fundus images; a module for receiving imported ones of the ocular fundus images and normalizing the ocular fundus images to produce normalized images; a module for coregistering the normalized images to produce normalized, co-registered images; a module for detecting differences between any two of the normalized, co-registered images; one or more modules configured to determine significant ones of the differences between the normalized, co-registered images and present only the significant ones of the differences in time sequence with an overlay of structural features of an eye which the images represent.