1. A method for normalizing laboratory instruments with pure dyes, comprising: providing at least one reference instrument and a test instrument, each instrument comprising at least one excitation filter and at least one emission filter arranged in pairs; providing a plurality of pure dyes, each dye comprising a fluorescent component and contained in a pure dye plate comprising a plurality of wells; generating fluorescent spectra from the reference instrument and the test instrument for multiple pure dyes across multiple filter combinations; creating a pure dye matrix, Mref, for the reference instrument and a pure dye matrix, M, for the test instrument; calculating correction factors for each the adjustment factors filter pair and multiplying the correction factors by the pure dye spectra; normalizing the corrected pure dye spectra; generating multicomponent data.