1. A system for package fill determination comprising a system controller; a data storage element; a historical data set acquisition element; a sampling manufacturing period acquisition element; a variance model acquisition element; a estimation technique acquisition element; a variance component set acquisition element; a first constraint set acquisition element; a first probability acquisition element; and a product data set acquisition element; wherein said system controller: (i) obtains a historical data set via said historical data set acquisition element; (ii) obtains a sampling manufacturing period via said sampling manufacturing period acquisition element; (iii) obtains a variance model via said variance model acquisition element; (iv) obtains an estimation technique via said estimation technique acquisition element, wherein steps (i), (ii), (iii) and (iv) may be conducted in any order; (v) determines a variance component set, acquired via said variance component set acquisition element, using said variance model, said estimation technique, and said historical data set; and (vi) determines a first target by the method comprising the steps of: a) obtaining a first constraint set via said first constraint set acquisition element; b) obtaining a first probability via said first probability selection element; c) obtaining a product data set via said product data set acquisition element, wherein steps (a), (b) and (c) may be conducted in any order; and d) calculating said first target utilizing said variance component set such that the probability of satisfying said first constraint set is at least as great as said first probability.