1. An imaging system, comprising: a gantry; a plurality of imaging detectors for acquiring imaging data, each of the imaging detectors having a length and a width of 20 cm or less, the plurality of imaging detectors mounted to the gantry and configurable to be arranged proximate to an anatomy of interest within a patient, the plurality of imaging detectors configured to move together in a circumferential path about the patient with the gantry when the gantry rotates about the patient and to be individually positionable to focus on the anatomy of interest when the gantry is stationary; a plurality of corresponding pinhole collimators, each pinhole collimator mounted or positioned proximate to one of the plurality of imaging detectors to define a field of view (FOV) for each imaging detector, at least a portion of the plurality of imaging detectors imaging the anatomy of interest within the respective FOV; a processor receiving the imaging data and processing the imaging data to form a multi-dimensional dataset having at least three dimensions; and a controller unit configured to control at least one of the plurality of imaging detectors or the plurality of pinhole collimators to individually focus the plurality of imaging detectors on the anatomy of interest, the controller unit further configured to control rotation of the plurality of imaging detectors with the gantry to a plurality of rotation positions about the patient, wherein, while the gantry is stationary at one of the rotation positions, the controller unit individually positions the at least one of the plurality of imaging detectors or the plurality of pinhole collimators about the anatomy of interest to acquire the imaging data while the imaging detectors are stationary, wherein the controller is configured to individually position the at least one of the plurality of imaging detectors by rotating the at least one of the plurality of imaging detectors about an axis that is parallel to an axis about which the gantry is configured to be rotated.