1. A semiconductor imager, comprising: a sensor array comprising a plurality of pixels arranged in rows and columns, each pixel of the plurality including at least one array isolation region configured to substantially isolate a first array-circuit-element from a second array-circuit-element; and peripheral circuitry arranged on at least one side of the sensor array, the peripheral circuitry including at least one periphery isolation region configured to isolate a first peripheral-circuit-element from a second peripheral-circuit-element, wherein the at least one periphery isolation region differs in configuration from the at least one array isolation region.