1. A method for registering a visual image and a spectral image of a biological sample, comprising: receiving a first set of coordinate positions of a plurality of reticles on a slide holder with the biological sample; receiving a visual image of the biological sample; receiving a second set of coordinate positions of the plurality of reticles on the slide holder with the biological sample; receiving a spectral image of the biological sample; aligning the first set of coordinates and the second set of coordinates; and generating a registered image with the spectral image and the visual image based upon the alignment of the first set of coordinates and the second set of coordinates.