1. A method of analyzing tissue from a breast image utilizing a system for analysis of tissue from a breast image, comprising: operating an electronic breast imager to provide an electronic image of breast tissue ( 100 , 400 , 450 , 600 , 800 , 1100 ); operating a histogram generating device to generate a histogram ( 500 , 700 ) representative of said electronic image of said breast tissue; running an inner breast detection 1310 ) on a histogram from an inner breast edge locating device to detect an inner breast edge of said breast tissue and to produce an inner breast edge location ( 1070 , 1170 , 1270 , 1315 ); determining a reference spot on said image of breast tissue using said inner breast edge location with a reference spot determining device; determining a calibration error with a calibration error determining device, and determining if said calibration error of said inner breast edge location is acceptable ( 1322 ); and determining, with a breast density analyzing device, whether said image of breast tissue is of dense breast tissue, and if said image of breast tissue is of dense breast tissue, determining a new reference spot with said reference spot determining device.