1. A method for analyzing probe array data to identify one or more alternative splicing events, the method comprising: normalizing a plurality of intensity values within a plurality of data sets, wherein the plurality of data sets include intensity values acquired from one or more probe arrays; selecting one or more subsets of intensity values within the plurality of intensity values; performing a signal estimate for each intensity value in the one or more selected subsets of intensity values; processing each of the signal estimates, thereby identifying one or more alternative splicing events, wherein the steps of normalizing, selecting, performing, and processing are performed on a computer.