1. A computer-implemented method for determining a level of significance for an image among a plurality of images in a study, said method comprising: selecting one or more parameters for use in determining a level of significance for a plurality of images in a study, wherein said one or more parameters include clinical relevance, segmented area, and reading time for each image in said plurality of images to determine said level of significance; assigning a value to each of said one or more parameters; determining, using a processor, said level of significance for each image in relation to said plurality of images in the study based on said parameters and said value associated with each of said one or more parameters; and outputting, using a processor, the plurality of images for viewing in an order determined based on said level of significance for each image.