1. A method of analyzing a structure-of-interest (SOI) in a patient, the method comprising: obtaining a first medical image of a patient, the first medical image including an identified structure-of-interest (SOI), the identified SOI having a corresponding local measurement; receiving a second medical image of the patient, wherein the first and second medical images were acquired at different times; selecting an SOI in the second medical image, the selected SOI having a corresponding local measurement; automatically determining that the selected SOI is the identified SOI based on corresponding location data of the identified and selected SOIs, respectively, and linking the local measurements of the selected and identified SOI; generating a report that compares the first and second local measurements, the report being displayed to the user to facilitate determining whether the identified SOI has changed in size or function; receiving a third medical image of the patient; selecting and SOI from the third medical image, the other selected SOI having a corresponding local measurement; automatically determining that the identified and selected SOIs in the first, second and third medical images are a common SOI; and adding the third local measurement to the report, the report including a mathematical relationship between the first local measurement and the second local measurement and a mathematical relationship between the first local measurement and the third local measurement.