1. An information processing system comprising: processing circuitry configured to: control a display to display an image generated based on a manipulation target image and an image based on a manipulation target region that is set based on a detection of an object included in acquired image data, wherein the manipulation target image includes a first area including a first manipulation target object capable of being manipulated by a detected input, and a second area including a second manipulation target object not capable of being manipulated by the detected input, and the processing circuitry is configured to control the display to display at least a portion of the acquired image data in the first and second areas, wherein a predetermined effect is applied to the displayed at least a portion of the acquired image data to differentiate the at least a portion of the acquired image data displayed in the first area from the at least a portion of the acquired image data displayed in the second area.