1. A method for imaging a biologic fluid sample having one or more constituents, which sample is quiescently disposed held by an analysis chamber, comprising: providing a spatial mapping of the analysis chamber, which spatial mapping defines a plurality of sub-regions of the analysis chamber; providing a predetermined repeatable non-uniform spatial distribution of at least one of the one or more constituents within the sample relative to the chamber, wherein the distribution indicates a probability that the at least one of the one or more constituents within the sample resides in particular sub-regions of the analysis chamber; selecting at least one imaging method for imaging one or more of the analysis chamber sub-regions based on the probability as indicated by the distribution; and creating image data representative of the biologic fluid sample in select chamber sub-regions, using the at least one imaging method selected for the respective one or more of the select chamber sub-regions.