1. A method for calibrating detectors of a tissue oximetry device comprising: transmitting source electrical signals to a first light source and a second light source; transforming, by the first and second light sources, the electrical signals into light based on the source electrical signals, emitting light having at least two wavelengths into a first tissue phantom from a first source structure and a second source structure that are optically coupled respectively to the first and second light sources; detecting the light by a plurality of detector structures, subsequent to reflection from the first tissue phantom, wherein the plurality of detector structures comprises a first detector structure, a second detector structure, a third detector structure, and a fourth detector structure, the first and second source structures and the first, second, third, and fourth detector structures are arranged on a probe face of the tissue oximetry device, a first distance is from the first detector structure to the first source structure, a second distance is from the first detector structure to the second source structure, the first distance is greater than the second distance, a third distance is from the second detector structure to the first source structure, a fourth distance is from the second detector structure to the second source structure, the fourth distance is greater than the third distance, a fifth distance is from the third detector structure to the first source structure, a sixth distance is from the third detector structure to the second source structure, the fifth distance is different from the first distance and the second distance, the sixth distance is different from the first distance and the second distance, a seventh distance is from the fourth detector structure to the first source structure, an eighth distance is from the fourth detector structure to the second source structure, the seventh distance is different from the first, second, and fifth distances, the eighth distance is different from the first, second, fifth, and sixth distances, the first distance is greater than each of the second, third, sixth, seventh, and eighth distances, and the second distance is less than each of the fifth, sixth, seventh, and eight distances; generating digital reflectance data points for the first tissue phantom from detected light detected by the first, second, third, and fourth detector structures; comparing digital reflectance data points for a reflectance curve for the first tissue phantom and the digital reflectance data points for the first tissue phantom for the detected light detected by the first detector structure for the first and second distances, the second detector structure for the third and fourth distances, the third detector structure for the fifth and sixth distances, and the fourth detector structure for the seventh and eighth distances; generating a set of calibration functions based on comparing the digital reflectance data points for the reflectance curve for the first tissue phantom and the digital reflectance data points for the first tissue phantom for the detected light detected by the first detector structure for the first and second distances, the second detector structure for the third and fourth distances, the third detector structure for the fifth and sixth distances, and the fourth detector structure for the seventh and eighth distances, wherein each calibration function in the set of calibration functions is associated with a unique, source structure-detector structure pair; and storing the set of calibration functions in a memory of the tissue oximetry device.