1. A system for detecting high-energy photons, comprising: a pixelated image detector exposed to visible light and to high-energy photons, wherein the pixelated image detector generates one or more images from the exposure of the pixelated image detector to the visible light; and one or more processors operably connected to the pixelated image detector and configured to perform operations on the one or more images, the operations comprising discriminating between the visible light that interacts with the pixelated image detector and the high-energy photons that interact with the pixelated image detector.