1. A method, comprising: obtaining real-time imaging data of a least a sub-portion of an object and a region of interest therein; displaying the real-time imaging data as the real-time imaging data is obtained; tracking extraction of a sample from the region of interest by an extraction device based on the real-time imaging data; and identifying an extraction location for the extracted sample based on the tracking and the real-time imaging data and generating a signal indicative thereof.