1. A computer-implemented method of image reconstruction and enhancement, the method comprising: acquiring image information associated with a target anatomy; determining a collection of images associated with the target anatomy; determining a subdivision of localized anatomy of the target anatomy, within each of the images; determining, using a processor, one or more associations between an image region of one of the images and a respective subdivision of localized anatomy of the one of the images; and generating an image reconstruction, an image enhancement, or a combination thereof for the target anatomy, based on the image information and the one or more determined associations.