1. A method of correcting orientational misalignment between a charged particle beam axis and a zone axis of a crystalline sample, comprising: irradiating the crystalline sample with the charged particle beam; recording a sample diffraction pattern, the charged particle diffraction pattern composed of multiple sample diffraction spots; correlating the intensity of the diffraction spots in the sample diffraction pattern with the intensity of corresponding diffraction spots of multiple reference diffraction patterns, each of the reference diffraction patterns corresponding to a known misalignment between the charged particle beam axis and the crystal zone axis; and adjusting to correct the sample orientation using the known misalignment of the reference pattern having the closest correlation with the sample diffraction pattern, wherein the recording of only a single sample diffraction pattern is required for adjusting to correct the sample orientation.