1. A method for refined segmentation of nodules in computer assisted diagnosis, the method comprising: testing, with a processor, a first processor determined segmentation as a function of computed tomography scan data; altering, with the processor, the scan data, a parameter or the scan data and a parameter where the first processor determined segmentation fails the testing; and determining a second processor determined segmentation as a function of the altered scan data, the parameter or the altered scan data and the parameter.