1. A method of operating an imaging device with a two-dimensional field of image sensors as well as an evaluation unit which is capable of reading out and processing the pixel signals, representing output signals of image sensors combined by a binning operation, at a maximum rate of no more than G max , comprising: presetting, on said imaging device, at least one parameter in order to define a sub-region of the field; and deriving, by said imaging device, any remaining parameters for defining the sub-region as well as a binning factor b and an imaging rate f, said deriving being performed, in view of the at least one preset parameter, in such a manner that the maximum rate G max of the evaluation unit is not exceeded during the reading out of all pixel signals from the sub-region, the location of said sub-region within said field being unique and corresponding to said at least one parameter and said any remaining parameters.