1. A method for automatically evaluating quality of a digital image of a magnified portion of a slide-mounted tissue sample comprising: automatically determining at least one quantitative quality indicator of a digital image of a magnified portion of a slide-mounted tissue sample by (i) identifying a plurality of different sub-regions within the digital image, (ii) automatically determining an average pixel intensity value for pixel intensity values within each of the plurality of different sub-regions (iii) comparing between different sub-regions the average pixel intensity value determined for each of the plurality of different sub-regions; and (iv) automatically determining for each sub-region a respective image position indicator as the at least one quantitative quality indicator; and automatically determining whether the at least one quantitative quality indicator meets a respective minimum acceptable quality threshold, failure of the at least one quantitative quality indicator to meet its respective minimum acceptable quality threshold being indicative of the digital image of the magnified portion of the slide-mounted tissue sample as considered unsuitable for automated pathological evaluation.