1. A computer program product embodied in a computer-readable medium for analyzing a first medical image to detect anatomical abnormalities therein, the first medical image acquired from a first type of imaging system having a first response characteristic, comprising: computer-aided detection (CAD) code comprising at least one neural network-based automated anatomical abnormality detection algorithm trained using training images acquired from a second type of imaging system having a second response characteristic different than the first response characteristic; and transforming code based on said first and second response characteristics for transforming pixel values of the first medical image to approximate values that would have been obtained if the first medical image had been acquired using the second type of imaging system such that said CAD code is applicable for the first medical image.