1. A region of interest ROI, segmentation system, comprising: a display device configured to display an image; a gaze-tracking device configured to generate gaze points relative to the displayed image; a gaze point collector configured to select gaze points from the generated gaze points corresponding to a ROI of the displayed image; a boundary identifier configured to estimate a boundary based on the selected gaze points; and a region identifier configured to segment the ROI based on the generated boundary.