1. A system for measuring particle deformability comprising: a substrate containing first and second microfluidic channels dimensioned to carry cells therein; an extensional region comprising an intersection of the first and second microfluidic channels, wherein the first and second microfluidic channels intersect in substantially opposite directions; at least one outlet channel coupled to the extensional region; an imaging device configured to capture a plurality of image frames of cells passing through the extensional region; and at least one processor configured to calculate a morphological parameter of the particle passing through the extensional region.