1. A method of generating motion-corrected images comprising: acquiring a plurality of acquired projections of a subject in an examination region at each of a plurality of angular orientations; reconstructing the acquired projections into a motion-artifacted image; forward-projecting the motion-artifacted image along each of a plurality of projection directions corresponding to the angular orientations of the measured projections to generate a plurality of forward-projections; comparing the acquired projections and the image degrading factor forward-projections corresponding to the same angular orientation to generate a patient motion vector; applying the motion-correction vector to form motion-corrected projections in a common motion state; reconstructing the motion-corrected projections into a motion-corrected image; and correcting or modeling at least one image degrading factor in at least one of the reconstructing, forward-projection, comparing, and motion correction applying steps.