1. A method of producing a mammalian vascular state score applicable to predict surgical intervention outcome, the method comprising: receiving vascular image data including: relative positions in one or more two-dimensional angiographic images of a plurality of vascular segments linked by branch points, and at least one lesion for which a respective lesion complexity includes a degree of occlusion, and a position relative to the vascular segments; determining automatically a plurality of lesion complexity-related vascular metrics for each of a plurality of said vascular segments, based on at least one angiographic image of said received image data; determining said lesion complexity for use as an at least one subscore of a vascular state scoring tool; wherein the lesion complexity is based on said plurality of vascular metrics, and on said position of the lesion within the vascular segments and relative to the branch points, the position including a determined number of vascular segments that the lesion comprises; and calculating said vascular state score based on said at least one subscore.