1. Method of MR imaging of at least a portion of a body of a patient positioned in an examination volume of a MR device, the method comprising the steps of: subjecting the portion of the body to a calibration sequence comprising RF pulses and switched magnetic field gradients controlled in such a manner that a calibration signal data set is acquired by means of a multi-point Dixon technique at a first image resolution; segmenting a water segment and a fat segment from the calibration signal data set deriving calibration parameters for each of the water segment and the fat segment from the calibration signal data set; wherein shim settings are derived from the calibration signal data set, which shim settings are used for controlling currents through shimming coils of the MR device and subjecting the portion of the body to an imaging sequence comprising RF pulses and switched magnetic field gradients controlled in such a manner that a diagnostic signal data set is acquired at a second image resolution which is higher than the first image resolution; and reconstructing a diagnostic MR image from the diagnostic signal data set, wherein the MR device is operated according to the derived calibration parameters during acquisition of the diagnostic signal data set and/or during reconstruction of the diagnostic MR image.