1. A method for initially calibrating an image capture device, comprising: receiving a captured image of at least one test target; resolving the captured image; determining at least one sharpness index by analyzing the resolved image in a frequency domain; determining a cost function based on the at least one sharpness index, wherein the at least one sharpness index includes at least a first sharpness index and a second sharpness index, and wherein the first sharpness index corresponds to a slanted edge modular transfer function (MTF) that is based on an edge spread function and the second sharpness index corresponds to a texture modular transfer function (MTF) that is based on a power spectral density of the resolved image; minimizing the cost function to determine sharpness parameters; and storing the sharpness parameters for use by the image capture device.