1. In a digital medium environment, a method implemented by at least one computing device, the method comprising; generating, by the at least one computing device, a color estimate for a plurality of pixels within a region of an image, the generating including: identifying a plurality of pixels of the image outside of the region of the image for each pixel of the plurality of pixels within the region, in which at least two of the identified plurality of pixels are identified based on disposition at opposing directions, one to another, from the pixel within the region; and determining the color estimate for each of the plurality of pixels within the region based at least in part on the identified plurality of pixels outside of the region; initializing, by the at least one computing device, an imaging process to compute color values for the plurality of pixels within the region using the color estimate for each of the plurality of pixels within the region, wherein the imaging process is configured to perform at least one of hole filling, content-aware fill, image healing, image restoration, or image editing; and outputting, by the at least one computing device, a result of the imaging process having the color values for the plurality of pixels within the region.