1. A portable image acquisition and processing device which automatically detects and corrects face region defects within digital images, comprising a processor, image sensor and lens to acquire digital images, and a memory having code embedded therein for programming the processor to perform a multiple image defect detection and correction method that comprises: using the processor, image sensor and lens to acquire and process a main digital image; applying an analysis filter to one or more preview or other reference images of approximately a same scene as said main digital image; interpreting results of the applying said analysis filter; determining an optimal correction strategy for application to the main digital image based on the interpreting; determining an optimal combination of corrective image processing and filter adaptation based on the strategy; and correcting multiple image defects based on said applying said analysis filter in accordance with said optimal combination, including detecting and correcting one or more defects within a specific region of interest within said digital image.