1. A method for unfolding an image of a colon via skeletal subspace deformation comprising: deriving a centerline of a segmented image of said colon; computing a distance map encoding a nearest point of said centerline for each voxel on a wall of said colon; generating a polyhedral model of a lumen based on said segmented image of said colon; determining a neighborhood of points on said centerline for each vertex of the polyhedral model based on the distance map, wherein each point in the neighborhood is associated with a weight inversely proportional to a distance between a respective vertex and the centerline points in that neighborhood; performing a straightening operation on said centerline based on the weighted centerline points for each vertex of the polyhedral model for determining a straighten colon; performing a dissection image computation based on said straighten colon for deriving a texture image; and displaying said texture image of said straighten colon.