1. A method for detecting insertion, removal, and change of an object of interest through the comparison of a first image and a second image containing a common area of interest, the method comprising using a computing device to identify and prioritize image regions within the images based on changes in feature content over time in a manner that is consistent with the insertion, removal and change of the object of interest, the identification and prioritization including: performing a scene registration including aligning image patterns in the first image to those in the second image; performing a feature content analysis to determine a General Pattern Change (GPC) likelihood of change over time for each pixel in the first and second images; performing a region identification to group pixels within the first and second images into one or more image regions based upon their likelihood of change; and performing an image region partitioning to prioritize the one or more image regions according to an image region score for each of the one or more image regions, the image region score being indicative of insertion, removal, and change over time of an object of interest within the common area of interest.