1. A method for refined segmentation of nodules in computer assisted diagnosis, the method comprising: testing, with a processor, a first processor-determined segmentation of a nodule, the testing being a function of computed tomography scan data used to segment the first processor-determined segmentation of the nodule; altering, with the processor, the scan data used to segment the first processor-determined segmentation of the nodule, a parameter for segmenting, or the scan data and the parameter where the first processor-determined segmentation fails the testing; and re-determining the segmentation of the nodule such that a second processor-determined segmentation is determined from the scan data as a function of the altered scan data, the altered parameter or the altered scan data and the altered parameter.