1. A non-transitory computer-accessible medium having stored thereon computer executable instructions for generating a genome wide probe map which, when the executable instructions are executed by a processing arrangement, configure the processing arrangement to perform a procedure comprising: (a) obtaining at least one plurality of at least one detectable oligonucleotide probe hybridized to at least one double stranded nucleic acid molecule cleaved with at least one restriction enzyme; and (b) detecting the location of the plurality of at least one detectable oligonucleotide probe to generate a genome wide probe map.