1. An apparatus for tomosynthesis imaging comprising: an x-ray source configured to irradiate an object with a beam of x-rays; a detector configured to detect the x-ray beam that passes through the object; and a computer programmed to: perform a single scan, the single scan comprising: a translation of at least one of the x-ray source and the detector along a path during the single scan; an acquisition of a tomosynthesis image dataset during the single scan; and a reconstruction of two or more three-dimensional (3D) volumes respectively adapted to two or more predetermined view directions from the tomosynthesis image dataset, wherein at least one of the two or more predetermined view directions is aligned outside of a central view, the at least one predetermined view direction corresponding to a location of the x-ray source different than a location of the x-ray source corresponding to the central view, the at least one redetermined view direction being non-orthogonal to an x-ray detector plane of the detector and distinct from a view direction of the central view.