1. A method for navigating a device to a target location in a target area of a moving organ of a subject, the method comprising the steps of: acquiring at least one reference image under a first set of geometric conditions, the reference image showing the target area and at least one first feature attached to the moving organ; defining the target location for the device on the reference image; determining a geometric relation between the at least one first feature and the target location; acquiring at least one positioning image; detecting a second feature in the at least one positioning image; and indicating to a user a discrepancy between the target location and a current location of the device, using the second feature and the geometric relation.