1. A system having at least one processor, storage, and a communication platform connected to a network for analyzing an image, the system comprising: a trial specification unit, implemented on the at least one processor, configured to obtain one or more imaging protocols, each of which specifying how an image is to be acquired; an encoding unit, implemented on the at least one processor, configured to encode information related to clinical trial protocols including the one or more imaging protocols; the communication platform configured to transmit the encoded information related to clinical trial protocols, via the network, to an acquisition unit, so that the acquisition unit can acquire an image based, at least in part, on the one or more imaging protocols and append the encoded information related to clinical trial protocols to the acquired image, and receive the acquired image appended with the encoded information related to clinical trial protocols from the acquisition unit; an application dispatch unit, implemented on the at least one processor, configured to decode the appended information related to clinical trial protocols, identify a clinical trial protocol from the decoded information related to clinical trial protocols, and initialize a software application based on the identified clinical trial protocol; an analysis unit, implemented on the at least one processor, configured to perform an analysis of the received image utilizing the software application to obtain an analysis result; and an application result compensation generation unit, implemented on the at least one processor, configured to apply compensation data to the analysis result, wherein the compensation data is obtained from statistical analysis of prior use of the software application.