1. Method for generating a microscope image, comprising a) illuminating a specimen by way of a microscope objective lens by means of a TIRF method and b) illuminating said specimen in a structured way in different shift positions of the structure, the specimen light of the method according to subparagraphs a) and b) hereof is detected in each instance in order to generate images of at least one specimen area, and wherein specimen images, generated according to paragraphs a) and b), are balanced relative to each other, preferably multiplied; and storing results in order to generate a new specimen image.