1. A method comprising: positioning a sample in a field of view of a spectroscopic device; obtaining a first spectroscopic data set for the sample positioned in said field of view; storing positional information about said field of view; treating the sample with a contrast enhancing agent; repositioning the treated sample in said field of view of the spectroscopic device using said stored positional information about said field of view; obtaining a digital image of the treated sample positioned in said field of view; linking said first spectroscopic data set with said digital image; and classifying a disease state of said sample, wherein said classification comprises: providing a database having at least one representative spectroscopic data set wherein said representative spectroscopic data set is characteristic of a disease class, and for said first spectroscopic data set, searching said database to thereby identify a representative spectroscopic data set therein that matches said first spectroscopic dataset to thereby classify a disease state of said sample.