1. A method for monitoring a patient-performed drug delivery from a hand-held container to a region of interest (ROI) associated with the patient's body, the method comprising: applying hand input to a drug-delivery system to squeeze a drop of a drug from a tip of the container and to release said drop from said tip, the drug-delivery system including the container containing said drug and a container-holding system having a first frame component structured to house the container therein along an axis thereof and a second frame component extending from the first frame component, the second frame component carrying an imaging camera having an optical field-of-view (FOV), an optical detector, and configured to record images of a scene within the FOV, the FOV covering the tip, the ROI, and a space separating the tip from the ROI; recording a series of image frames, each frame representing a corresponding position of said drop in said space; and producing a report representing whether said drop landed in, partially in, or out of the ROI, wherein the producing includes determining target image frames from the series, said target image frames represent only an advancement of said drop through said space.