1. A device for estimating oxygen saturation in the presence of noise, the device comprising: a processor in communication with a radial basis neural network, wherein the processor is configured to receive optical oximetry data, process the optical oximetry data to produce at least one oxygen saturation estimate, communicate the at least one oxygen saturation estimate to the radial basis neural network, and receive a modified oxygen saturation estimate comprising less noise bias than the at least one oxygen saturation estimate from the radial basis neural network, wherein the radial basis neural network is configured to define the modified oxygen saturation estimate based at least in part on combining the at least one oxygen saturation estimate with corresponding signal quality metrics; and a display in communication with the processor, wherein the display is operable to display a representation of the modified oxygen saturation estimate.