1. An image processing device that registers at least two images of an object, comprising: a processor configured: to execute a global registration of the at least images using a given registration algorithm with a first parameter vector; to select of a region of interest (ROI) in the images; and to execute at least one local registration of the at least images within the selected ROI using the given registration algorithm with a different parameter vector; wherein a parameter vector is determined for at least one local registration based on an automatic analysis of the ROI which comprises the evaluation of: intensity ranges, intensity histograms, image edges, edge histograms, entropy measurements, intensity range of residuum, and/or anatomical position.