1. A method for iterative reconstruction of tomographic images of an object of interest comprising: obtaining projection data in a field of view of a detector over a plurality of projection view angles, wherein said projection data includes data of said object; processing the projection data to prepare a projection reconstruction support region within said field of view, in which said object is located; and reconstructing a tomographic image of said object from projection data located in said reconstruction support region wherein said reconstruction is iterative and comprises: modifying a system matrix with view specific attenuations for all voxels in said reconstruction support region; projecting forward, support voxels provided by applying said system matrix; calculating projection correction as a ratio between an estimated projection and an actual projection; projection correction for voxels encompassed by the reconstruction support regions are back projected; and, summing back-projected corrections to update said support voxels.