1. A system comprising: one or more processors; a memory in operative connection with the one or more processors; wherein, responsive to execution of program instructions accessible to the one or more processors, the one or more processors are configured to: access one or more digital specimen images; generate one or more patient records and one or more case records; match the one or more digital specimen images to the one or more case records based on one or more image properties of the one or more digital specimen images; and facilitate one or more image review functions comprising image quality, case matching, tissue block matching, and case completeness functions.