1. A computer-implemented method for improving the image quality of a digital slide image in a digital environment for the management and interpretation of pathology information, the method comprising: receiving a digital slide image of a tissue sample at diagnostic resolution, wherein the tissue sample has been stained using three or more stain types; deconvolving the digital slide image into three or more single images having one of the three or more stain types per single image; processing the three or more single images with an image quality algorithm to optimize the quality of the three or more single images; and recombining two or more of the optimized three or more single images into two or more recombined digital slide images at diagnostic resolution, wherein each of the two or more recombined digital slide images comprises a different combination of two or more single images than others of the two or more recombined digital slide images, and wherein at least one of the two or more recombined digital slide images comprises a combination of at least two, but not all, of the three or more single images.