1. An image sensing device comprising a solid-state image sensor with at least one radiation-sensitive element to convert incident radiation into an electric charge, a read-out circuit to form a pixel signal from the electric charge, which pixel signal includes at least a hold level and an image level while the image sensing device comprises a signal processing circuit to determine the difference between the hold level and the image level and to derive an electronic image signal from the difference, characterized in that the signal processing circuit comprises a clamping circuit including a low-pass filter to relate a low-pass filtered hold level of the pixel signal to a reference level.