1. An image processing device that can register at least two images of an object, comprising: a “global registration module” for executing a global registration of the images using a given registration algorithm with a first parameter vector; a “selection module” for the selection of a region of interest, called ROI, in the images; a “local registration module” for executing at least one local registration of the images within the selected ROI using the given registration algorithm with a different parameter vector; wherein a parameter vector is determined for at least one local registration based on an automatic analysis of the ROI which comprises the evaluation of: intensity ranges, intensity histograms, image edges, edge histograms, entropy measurements, intensity range of residuum, and/or anatomical position.