1. A method for tissue biopsy and imaging, comprising: extracting a tissue sample using a biopsy device; aspirating the tissue sample from the biopsy device through a flexible tissue aspiration line into a tissue holding compartment of a tissue sample holder positioned in a fluid communication path between the biopsy device and a vacuum source, wherein the tissue holding compartment is aligned with an outlet of the tissue aspiration line to receive the tissue sample; while the tissue sample holder remains positioned in the fluid communication path between the biopsy device and vacuum source, moving the tissue sample holder to position the tissue holding compartment, including the tissue sample, within an imaging field of an imaging system; and acquiring an image of the tissue sample using the imaging system.