1. An imaging system for use in a medical intervention procedure, comprising: a first image acquisition system of a first modality employing a catheter at an anatomical region of a patient and configured to produce a first image of the anatomical region using fluoroscopy, the first image comprising a set of fluoroscopy projection images; a second image acquisition system of a second different modality configured to generate a 3D model of the anatomical region; an anatomical reference system common to both the first and second image acquisition systems; and a processing circuit configured to process executable instructions for registering the 3D model with the fluoroscopy image in response to the common reference system and discernible parameters associated with the catheter in both the first and second image acquisition systems.