1. A method for image reconstruction of a three-dimensional (3D) digital breast tomosynthesis volume (DBT) in a plurality of slabs, the method comprising the following steps: analyzing a volume in order to detect diagnostically relevant data by determining a type of lesion; clustering the analyzed volume based on the determined type of information in at least a first region and a second region, the first region having a relatively high degree of diagnostically relevant data and the second region having a relatively low degree of diagnostically relevant data; determining a first reconstruction algorithm for the first region and a second reconstruction algorithm for the second region; determining a first slab thickness for the first region and a second slab thickness for the second region; and reconstructing the volume such that the first region is reconstructed with the first reconstruction algorithm with a relatively high resolution in relatively thin slabs and the second region is reconstructed with the second reconstruction algorithm with a relatively low resolution and relatively thick slabs.