1. An imaging system for imaging skin, comprising: one or more light sources configured to illuminate a subject; one or more photodetectors configured to acquire images of the subject as illuminated by at least one of the one or more light sources; one or more adjustable polarizers, each coupled with a respective photodetector of the one or more photodetectors and configured to provide an adjustable axis of polarization of light received by the respective photodetector; one or more processors; and memory storing one or more programs for execution by the one or more processors, the one or more programs including instructions for: acquiring a first image of the subject in a first polarization with the respective photodetector; acquiring a second image of the subject in a second polarization with the respective photodetector; generating a subtraction image by subtracting at least a portion of the first image from a corresponding portion of the second image; and providing at least a portion of the subtraction image for display.