1. A method for acquiring region-of-interest specific sequence data, comprising: selecting a plurality of probes of interest; generating a cell map comprising an image of a tissue sample on which biomarker expression data generated using the selected probes is displayed; identifying one or more regions-of-interest within the cell map in which cells are tagged by one or more of the probes; extracting one or more cells from at least one of the regions-of-interest from the tissue sample; and sequencing nucleic acids present in the one or more cells to generate region-of-interest based sequence data.