1. A method for evaluation of a multi-component medicine comprising judging the degree of difference of the multi-component medicine to be evaluated from a group of multi-component medicines selected as a reference group by using a Mahalanobis distance obtained by a process comprising (1) obtaining fingerprint data of three-dimensional high performance liquid chromatography of the multi-component medicine to be evaluated, (2) combining the fingerprint data obtained in (1) with fingerprint data of three-dimensional high performance liquid chromatography of other multi-component medicines of the same kind forming a reference group, (3) allocating variable axes in the MT method to the number of multi-component medicine and the elution time or detection wavelength of the fingerprint data of (2) above and regarding a signal strength as a characteristic amount in the MT method, (4) obtaining a unit space from the characteristic amount of (3) using the MT method, and (5) obtaining the Mahalanobis distance of the multi-component medicine to be evaluated using the MT method from the unit space obtained in (4).