1. A method, comprising: receiving a first data set corresponding to patient data at a first time, the first data set comprising a first brain scan; receiving a second data set corresponding to patient data at a second time, the second data set comprising a second brain scan; segmenting a first region of interest in the first data set, wherein the first region of interest is a portion of the first brain scan and comprises a first and a second structure, the second structure being a mirror of the first structure across the sagittal plane; segmenting a second region of interest in the second data set, wherein the second region of interest is a portion of the second brain scan and comprises the first and second structures, wherein the segmented first and second regions correspond to one another; and aligning the segmented first region of interest with the segmented second region of interest to highlight a first contour indicating a change in size, shape and orientation between the segmented first and segmented second regions of interest, the first contour being the change on the segmented second region of interest.