1. An image processing apparatus for use in biology, histology and pathology, the image processing apparatus comprising: an input port (IN) for receiving a plurality of image frames from a first imaging procedure and a first image from a second imaging procedure, the first image serving as a first reference template; an image matcher (M) switchable between a first mode and a second mode, wherein the matcher attempts matching image frames of the plurality of image frames from the first imaging procedure to the first reference template when the matcher operates in the first mode, and wherein the matcher switches to the second mode when a first matching image frame, determined as an image frame of the plurality of image frames that matches the first reference template according to a first threshold, is found from among the image frames, or when a user issued switch signal is received corresponding to a current image frame of the image frames, and then uses the first matching image frame or the current image frame, respectively, as a second reference template in the second mode instead of the first reference template to attempt matching subsequent image frames of the plurality of image frames to the second reference template; and an output port (OUT) for outputting a further matching image frame, determined as an image from the subsequent image frames that matches the second reference template according to a second threshold, found from among the subsequent image frames of the plurality of image frames.