1. A system, comprising: a patient information receiver circuit configured to receive patient information including one or more physiologic signals obtained from a patient, and to generate a plurality of signal trends from the one or more physiologic signals; at least two categorical risk analyzer circuits, including: a category-specific input selection circuit configured to receive a category-specific input including at least a portion selected from the plurality of signal trends based on an associative physiologic condition indicative or correlative of a target physiologic event; a signal trend analyzer circuit configured to generate, for at least one of the selected portion of the plurality of signal trends, a signal trend metric including a signal change indicator indicative of a level of signal change; and a categorical risk calculator circuit configured to calculate a categorical risk index using the signal trend metric of the selected portion of the plurality of signal trends, the categorical risk index indicating a likelihood of the patient developing or presenting the associative physiologic condition; and a categorical fusion circuit coupled to the at least two categorical risk analyzer circuits, the categorical fusion circuit configured to generate a composite risk indicator using the categorical risk indices respectively provided by the at least two categorical risk analyzer circuits, the composite risk indicator indicative of a likelihood of the patient developing the target physiologic event.