1. A system for segmenting a time series of image frames in an anatomical scan, the system comprising: a user input device configured for manually segmenting an image frame k in the time series of image frames; an image processor configured to perform a non-rigid registration between the image frame k and a next image frame k+1 in the time series of image frames and compute a segmentation on the image frame k+1 based on the non-rigid registration, the image processor further configured to iteratively segment each subsequent image frame k+n in the time series of image frames using non-rigid registration with the segmented previous image frame k+(n−1) in the time series of image frames.