1. A system for combining multiple datasets to provide a composite dataset, comprising: a data collection tool; a computation engine and a memory coupled to the data collection tool; and computer-readable code embodied on a computer-readable medium and configured so that when the computer-readable code is executed by one or more processors associated with the computation engine the computer-readable code causes the one or more processors to: accept two or more datasets corresponding to distinct measurements of a subject; initiate processing of the two or more datasets; contemporaneously segment and register a combination of the two or more datasets to achieve a combined dataset; test for convergence of the combined dataset; and provide the combined dataset for analysis when the test for convergence indicates that the combined dataset has been registered and segmented.