1. An imaging system which generates a patient image collective, comprising: a data store which stores a collective of images; one or more processors programmed to: a) receive a plurality of candidate images and associated data for inclusion in the collective of images; b) apply at least one inclusion/exclusion rule to the plurality of candidate images and the associated data which results in a subset of candidate images; c) test the candidate images based on at least one quality measure; d) review the at least one quality measure and the candidate images; e) refine the at least one inclusion/exclusion rule based on the reviewed at least one quality measure by at least one of: adding a rule, modifying a rule, deleting a rule, removing a candidate image; and adding a candidate image; repeat b)-e) until an optimized collective of images is generated based on the collective size and reviewed at least one quality measure; and output at least one generated collective to the data store or to a display.