1. A medical imaging system for generating 3D anatomical imaging volume datasets from acquired 2D anatomical images, comprising: an image acquisition device for acquiring 2D anatomical images of a portion of patient anatomy in selectable angularly variable imaging planes in response to a synchronization signal derived from a patient blood flow related parameter; a synchronization processor for providing said synchronization signal derived from said patient blood flow related parameter; and an image processor for processing 2D images acquired by said image acquisition device of said portion of patient anatomy in a plurality of different imaging planes having relative angular separation, to provide a 3D image reconstruction of said portion of patient anatomy.