1. A super resolution optofluidic microscope device, comprising: a body defining a fluid channel having a longitudinal axis, the body including a surface layer proximal the fluid channel, the surface layer having a two-dimensional light detector array configured to receive light passing through the fluid channel and sample a sequence of subpixel shifted projection frames as an object moves through the fluid channel; and a processor in electronic communication with the two-dimensional light detector array, and configured to generate a high resolution image of the object using a super resolution algorithm and based on the sequence of subpixel shifted projection frames and a motion vector of the object.