1. A method for generating at least one image of a region of interest in a patient, the method comprising: obtaining at least two radiological images of the region of interest with a medical imaging system, wherein the at least two radiological images are identified with at least one marker arranged on and/or around the patient, wherein a first image was acquired with a first X-ray energy and a second image was acquired with a second X-ray energy; and determining with a processing system of the medical imaging system a final radiological image of the region of interest by linearly combining the two radiological images to obtain an image without the markers.