1. A method for non-invasive assessment of an arterial stenosis, comprising: segmenting a plurality of mesh candidates for an anatomical model of an artery including a stenosis region of a patient from medical imaging data; computing a hemodynamic index for the stenosis region in each of the plurality of mesh candidates; and determining whether a variation among values of the hemodynamic index for the stenosis region in each of the plurality of mesh candidates is significant with respect to a threshold associated with a clinical decision regarding the stenosis region by determining whether the variation among values of the hemodynamic index for the stenosis region in each of the plurality of mesh candidates is entirely below the threshold for the clinical decision or is entirely above the threshold for the clinical decision.