1. A method of tracking a target region in an image frame based on a target region of a previous image frame in a sequence of image frames, each of said sequence of image frames comprising a plurality of pixels, said method characterized by: determining a search area in said image frame based on at least a part of the target region in said previous frame, said search area comprising a plurality of first pixels, each pixel having at least one corresponding first pixel value; and for the first pixels in the search area: determining a further search area in said previous frame, said further search area including a plurality of second pixels among the plurality of pixels in the previous frames, each second pixel having at least one corresponding second pixel value and a region status; finding a match between the first pixel value of said first pixels among the second pixel values for locating a reference second pixel; and determining the region status of at least one of said first pixels based on the region status of the reference second pixel for determining the target region in said image frame based on the region status of said at least one first pixel.