1. A method comprising: determining a probability for each voxel in a patient-specific image data set that the voxel belongs to one or more vascular regions of interest; segmenting patient-specific vasculature in the patient-specific image to generate a set of nodes and edges representative of the patient-specific vasculature; classifying each node and edge based on one or more statistics associated with each node and edge; and determining to which of the one or more vascular regions of interest each voxel in the patient-specific image data set belongs based on the probability and the classifications.