1. A method comprising: evaluating, with a processor, first image space data that includes a lesion and vasculature to determine a spatially varying strength of the vascular connections between locations in the first image space and the lesion; identifying, with the processor, in the first image space data, a first path that represents a vascular connection to the lesion, wherein the path includes a first location; identifying, with the processor, a second location along the path that satisfies a predetermined connection strength threshold between the first location and the lesion; and generating, with the processor, second image space data indicative of the determined spatially-varying strength.