1. A method of processing infrared images of a scene captured by an infrared image sensor comprising a plurality of sensor elements, the method comprising: receiving a first frame comprising a first plurality of pixel data of a first infrared image; receiving a second frame comprising a second plurality of pixel data of a second infrared image; determining frame-to-frame motion between the first frame and the second frame, wherein the frame-to-frame motion identifies portions of the first and second pixel data corresponding to identical scene coordinates captured by different sensor elements for the first and second frames; determining irradiance differences between the first and second portions of pixel data; and determining pixel offset information for scene based non-uniformity correction terms based on the irradiance differences and the frame-to-frame motion.