1. A parameter generation system to determine at least one parameter for an injection procedure to be performed on a patient in connection with a diagnostic imaging procedure, the injection procedure including an injection of a contrast enhancement fluid that includes a contrast enhancing agent adapted to enhance a contrast of images obtained with an imaging system, the parameter generation system comprising: (a) at least one processor for controlling operation of the parameter generation system; and (b) one or more algorithms stored in a non-transitory computer readable medium and operably associated with the at least one processor, the one or more algorithms embodying a model descriptive of propagation of a fluid within the patient from a site of the injection thereof to each of at least two regions of interest thereof, the one or more algorithms enabling: (I) input into the model of as few as one discrete data point from each of at least two time enhancement curves to determine values of physiological parameters associated with the patient, each of the time enhancement curves being associated with one of the at least two regions of interest and each of the discrete data points constituting a pair of measurements on the time enhancement curve corresponding thereto, the time enhancement curves resulting from a scan of the at least two regions of interest as a test bolus of the contrast enhancement fluid injected into the patient flowed therethrough; and (II) upon determination of the values of the physiological parameters, substitution of the values of the physiological parameters into the model to determine the at least one parameter for the injection procedure with which to generate desired levels of enhancement in the images obtained from the at least two regions of interest during the diagnostic imaging procedure.