1. A non-transitory computer-readable storage medium comprising: one or more programs comprising instructions executable by a hyperspectral/multispectral imaging system comprising an optical acquisition system in electronic communication with a diagnostic processor, and one or more diagnostic protocol modules; wherein the optical acquisition system comprises (i) a first stage optic responsive to illumination of a tissue surface of a patient, (ii) a spectral separator optically responsive to the first stage optic, and (iii) an imaging sensor optically responsive to the spectral separator and having an image data output, the one or more programs including instructions for: (A) selecting, in response to a user input, a diagnostic protocol stored by the one or more diagnostic protocol modules: (B) instructing the spectral separator to apply a series of filter transfer functions to light collected from a tissue surface of a patient using the hyperspectral/multispectral imaging system according to the selected diagnostic protocol; (C) instructing the imaging sensor to acquire a plurality of filtered images of the tissue surface of the patient, each respective filtered image in the plurality of filtered images acquired at one or more spectral bands corresponding to a respective filter transfer function in the series of filter transfer functions; and (D) processing the plurality of filtered images according to instructions provided by the selected diagnostic protocol.