1. An imaging system comprising: a primary imaging sensor configured to detect electromagnetic radiation in a first spectral band and to produce first image data comprising a plurality of image frames; a secondary imaging sensor configured to detect electromagnetic radiation in a second spectral band, different from the first spectral band, and to produce second image data time-synchronized with the first image data; a computation module coupled to the secondary imaging sensor and configured to analyze the second image data and produce alignment data; and an alignment module coupled to the primary imaging sensor and to the computation module, and configured to receive the alignment data and the first image data and to align and stack the plurality of image frames to produce an aligned image stack.