1. A brain image pipeline method for operating an electronic device, comprising: receiving a patient's brain image and patient information characterizing the brain image, wherein the patient's brain image has a predictor region; accessing a database having a plurality of brain images different than the patient's brain image and patient information characterizing each of the brain images, wherein the database includes a plurality of different types of magnetic resonance imaging images; retrieving from the database a patient-specific training set of a plurality of brain images having patient information that matches the patient information of the patient's brain image, wherein each brain image of the training set has a predictor region associated with a predictive region that is anatomically different than the predictor region, and wherein the predictor region corresponds to the predictor region in the patient's brain image; processing the patient-specific training set of brain images to extract predictor information representative of a predicted region of interest having a predicted shape and a predicted location and orientation based on relationships between the shapes, locations and orientations of the predictive regions in the training set of brain images with respect to the shapes, locations and orientations of the predictor regions in the training set of brain images; and processing the patient's brain image using the predictor information to incorporate the predicted region of interest having the predicted shape, location and orientation into the patient's brain image with respect to the predictor region in the patient's brain image, to produce an enhanced patient-specific image having the predicted region of interest.