1. A method of detecting an intravascular probe marker comprising: obtaining a first frame of angiography image data that is substantially free of contrast agent image data and includes the intravascular probe marker, the first frame stored in one or more electronic memory devices; obtaining a second frame of angiography image data that comprises contrast agent image data in a vicinity of the intravascular probe marker, the second frame stored in the one or more electronic memory devices; detecting, using an intravascular data collection system, the intravascular probe marker in the first frame and the second frame; processing the plurality of pullback frames using a Hessian-based vessleness filter; and tracking the intravascular probe marker from one of the first frame or the second frame through the plurality of pullback frames using template matching.