1. A computer implemented system to digitally quantify alignment and placement parameters in a musculoskeletal application comprising: a computer system coupled to: i. an image capturing module configured to capture an operative image of a portion of said patient's body; and obtain a reference image of a contra lateral side of said portion of said patient's body; ii. a calibration and anatomical matching module coupled to said image capturing module and configured to 1. calibrate said reference image and said operative image to same magnification; 2. identify at least one first anatomic marker in said reference image and at least one second corresponding anatomic marker in said operative image; and 3. produce an overlaid image by overlapping said reference image and said operative image together and anatomically aligning said at least one second anatomic marker against said at least one first anatomic marker on said overlaid image; and iii. a differential mapping module coupled to said calibration and anatomical matching module and configured to digitally quantify alignment and placement parameters in musculoskeletal applications based on said reference image and said operative image taken by said image capturing module with reference to a software generated virtual grid.