1. A method, comprising: determining a reference set of image features from an electronic data file specifying a reference image in a reference coordinate space; ascertaining rendering information describing a physical rendering of the reference image; deriving calibration-enabling data from the reference set of the image features and the ascertained rendering information; and providing the calibration-enabling data to calibrate an imaging system; wherein the determining, the ascertaining, the deriving, and the providing are performed by a processor.