1. A method for estimating a plurality of spaced apart, optics point spread functions of a lens assembly for use in processing an image, the method comprising: providing a test chart having a test chart pattern, wherein the test chart pattern is used to provide a latent sharp image; positioning a capturing system in a fixed position relative to the test chart; capturing a test chart image of the test chart with the capturing system using the lens assembly to focus light onto the capturing system; dividing the test chart image into a plurality of image areas, including a first image area and a second image area that is different from the first image area with a control system that includes a processor; dividing the first image area into a plurality of first area blocks with the control system, each first area block including a plurality of pixels; estimating a first area optics point spread function of the first image area with the control system by minimizing a first, non-blind, PSF cost function that sums fidelity terms of at least two of the first area blocks and uses a portion of the latent sharp image in the fidelity terms to estimate the first area optics point spread function using a spatially invariant convolution model for the first image area; dividing the second image area into a plurality of second area blocks with the control system, each second area block including a plurality of pixels; estimating a second area optics point spread function of the second image area with the control system by minimizing a second, non-blind, PSF cost function that sums fidelity terms of at least two of the second area blocks and uses a portion of the latent sharp image in the fidelity terms to estimate the second area optics point spread function using a spatially invariant convolution model for the second image area; capturing a subsequent image; and processing the subsequent image using at least one of the first area optics point spread function and the second area optics point spread function.