1. A system for acquiring image data of a subject with an imaging system, comprising: a gantry configured to encompass at least a portion of the subject, the subject positioned along an isocenter of the imaging system; a rotor positioned within the gantry and rotatable within the gantry around the isocenter of the imaging system; an imager source positioned within and movable relative to the gantry by being moveably coupled to the rotor, the imager source responsive to a signal to output at least one pulse; an image detector positioned within and movable relative to the gantry and the imager source by being moveably coupled to the rotor substantially opposed to the imager source, wherein the image detector is to detect the at least one pulse emitted by the imager source; and a move control module that sets move data based on a user input for each of the imager source, the image detector, and the rotor that causes the imager source, the image detector, and the rotor to move in a selected motion profile to acquire the image data of a portion of the subject that is off the isocenter of the imaging system; wherein the user input includes selecting an area of interest and the move control module is configured to determine movement of each of the imager source, the image detector, and the rotor that causes the imager source, the image detector, and the rotor to move in the selected motion profile to acquire the image data of the portion of the subject to acquire image data for generation of a reconstruction.