1. A computer implemented method for providing two dimensional and three dimensional digital slide data from a three dimensional digital slide image, where one or more processors are programmed to perform steps comprising: presenting on a display digital slide image data from a region of a three dimensional digital slide image comprising image data from only a single Z plane; receiving a request for digital slide image data from a region of the three dimensional digital slide image comprising image data from Z stack having a plurality of Z planes; determining the Z plane in said plurality of Z planes that is closest to said single Z plane; and presenting on the display digital slide image data from the requested region of the three dimensional digital slide image comprising image data from said closest Z plane.