1. A computer-implemented method for interactively displaying a three-dimensional rendering of a structure having a lumen and indicating regions having abnormal structure comprising the steps of: a. forming a three-dimensional volume of data from a series of two-dimensional images representing at least one physical property associated with the three-dimensional structure; b. segmenting a region of interest from the volume of data based on a selected value of the physical property representing the region of interest; c. generating a wire frame model of the segmented region of interest, the wireframe model comprising a plurality of vertices, each vertex having a coordinate position; d. grouping the vertices of the wireframe model into regions having a characteristic indicating abnormal structure; e. analyzing the regions having abnormal structure to identify regions having a high degree of abnormality; and f. rendering the wire frame model in an interactive three-dimensional display to indicate the regions having abnormal structure.