1. A method for the analysis of a biological sample to determine a change relative to a healthy biological sample, comprising: creating a first image of the biological sample at a first acquisition modality; creating a second image of the biological sample at a second acquisition modality, the first acquisition modality and the second acquisition modality being different, and the first acquisition modality and the second acquisition modality being selected from a group of acquisition modalities including a transmitted-light acquisition modality, a fluorescence acquisition modality, and a phase contrast acquisition modality; classifying the first image on the basis of a first predetermined parameter; classifying the second image on the basis of a second pre-determined parameter, the first image being classified independently of the second image; and depending on the classification results, determining if the biological sample comprises a change relative to a healthy biological sample.