1. A method for producing an image of a subject with a magnetic resonance imaging (MRI) system, the steps comprising: a) acquiring, with the MRI system, reference image data using a first pulse sequence that saturates a selected labile spin species by applying a radiofrequency (RF) irradiation at a reference frequency; b) acquiring, with the MRI system, labeled image data using a second pulse sequence that saturates a selected labile spin species by applying an RF irradiation at a labeling frequency; c) reconstructing a reference image from the acquired reference image data and a labeled image from the acquired labeled image data; and d) producing a corrected ratio image by subtracting the reconstructed labeled images form the reference images.