1. A method of verifying a registration of a digital image, said method comprising the steps of: receiving a reference image and a moving image that has been registered to said reference image, wherein said reference image and said moving image are representations of a same object, wherein each said image comprises a plurality of intensities defined for a 3D domain of points; selecting one or more landmarks in said images, and defining a neighborhood in the domain of each image near each selected landmark; extracting feature sets from the neighborhoods for the reference image and the registered moving image; calculating a total quality measure of the registration of the moving image from a distance metric applied to the feature sets extracted from the neighborhoods of the reference image and the registered moving image; comparing the total quality measure to a threshold determined from a reference atlas for the object represented in the image; and determining whether to accept or reject the registration of the moving image based on the comparison result.