1. A method for generating a three-dimensional synthetic image representative of an object undergoing an examination and representative of a target, comprising: acquiring a three-dimensional image of the object undergoing an examination via radiation; acquiring a three-dimensional image of the target, the target not subject to the examination; and combining, in three dimensional image space, the three-dimensional image of the object with the three-dimensional image of the target to generate the three-dimensional synthetic image whereby the target appears to be comprised within the object, the combining comprising casting artifacts on a portion of the three-dimensional synthetic image representative of at least one of: a first aspect of the object proximate the target, or the target.