1. A computer-implemented method for generating a presentation of a region-of-interest in an original image for display on a display screen, the method comprising: generating at least one intermediate level image corresponding to a region of the original image, said at least one intermediate level image being smaller in area than the original image and being magnified relative to the original image; generating a focal region image corresponding to a subregion of said region of the original image, said focal region image being smaller in area than the at least one intermediate level image and being magnified relative to the at least one intermediate level image; overlaying the at least one intermediate level image over the original image; and overlaying the focal region image over the at least one intermediate level image wherein generating at least one intermediate level image comprises: generating a first intermediate level image corresponding to a region of the original image, said first intermediate level image being smaller in area than the original image and being magnified relative to the original image; and generating a second intermediate level image corresponding to a subregion of the original image, said second intermediate level image being smaller in area than the first intermediate level image and being magnified relative to the first intermediate level image; and wherein generating the focal region image comprises generating the focal region image such that the focal region image is smaller in area than the second intermediate level image and is magnified relative to the second intermediate level image.