1. A method of detecting ligand/antiligand binding, comprising: obtaining measurements of an electromagnetically detectable bulk property of a mixture of a ligand and an antiligand for each of a plurality of initial ligand concentrations; processing a plurality of the obtained bulk property measurements and corresponding initial ligand concentrations to determine a relationship between the bulk property measurements of the mixture and the initial ligand concentrations as initial ligand concentration changes; and determining the formation or absence of a ligand/antiligand complex based on the relationship.