1. A method of analysis for an intravascular ultrasound (IVUS) image comprising: receiving an IVUS image; analyzing the IVUS image; determining an initial border of a region within the IVUS image based on the analysis of the IVUS image; receiving a first user input interacting with a display device to indicate one or more first control points on the IVUS image displayed on the display device, wherein each of the one or more first control points is independent of the initial border and located inside or outside of the initial border; determining a first modified border of the region based on the analysis and the first user input, the first modified border passing through the one or more first control points; displaying the IVUS image including the first modified border on the display device; wherein the steps of analyzing the IVUS image, determining the initial border and determining the first modified border are performed by one or more programmable processors; wherein the IVUS image is a single IVUS; dividing the IVUS image into a plurality of sectors; receiving a second user input indicating one or more second control points, wherein for each of the one or more second control points the second control point is located in one of the plurality of sectors either inside or outside of the modified border; and determining a second modified border based on the analysis, the first user input, and the second user input, wherein when at least one of the one or more first control points and at least one of the one or more second control points are both disposed the same sector of the plurality of sectors, the second modified border passes through the one or more second control points and ignores the one or more first control points.