1. A computer-readable medium having computer-readable instructions stored thereon which, as a result of being executed in a computer system having at least one input device, at least one processor, and at least one output device, instructs the computer system to identify and output suspicious regions of interest in a digital x-ray image of at least a portion of an anatomical region under study, said instructions comprising instructions for a. receiving, through at least one input device, a digital x-ray image of at least a portion of an anatomical region under study, the digital x-ray image being characterized by first global noise characteristics; b. computing, in at least one processor, a first global noise estimate for at least a portion of the received image; c. computing, in at least one processor, a modified digital x-ray image of at least a portion of the anatomical region under study, the modified digital x-ray image being characterized by second global noise characteristics, wherein, the modified digital x-ray image has associated with it a second global noise estimate of about a predetermined noise value; d. identifying, in at least one processor, at least one suspicious region of interest in the at least a portion of the anatomical region under study using the modified digital x-ray image; and e. outputting, through at least one output device for use by at least one user, information associated with the at least one suspicious region of interest identified.