Data from seven randomized , double blind , placebo controlled , 6 - to 12-week efficacy trials of olmesartan 20 mg and 40 mg/day were analyzed to determine changes in trough seated SBP and PP within three cohorts : 1 ) total cohort ( n = 1777 ) ; 2 ) subjects with a wide PP : that is , those with a baseline PP > 55 mm Hg ( n = 917 ) ; and 3 ) a subpopulation of patients with a wide PP and age > or = 65 years ( n = 296 ) .
