Salmeterol treatment had no effect on sputum eosinophils geometric mean , ( from 35.5 [ 24.9 ] to 26.9 % [ 25.8 ] ) , blood eosinophils ( from 7.6 [ 4.8 ] to 7.2 % [ 3.9 ] ) or ECP ( from 33.1 [ 18.1 ] to 27.8 [ 16.3 ] mg/L ) but improved morning peak expiratory flow ( PEF ) and diurnal variation of PEF , and decreased the use of rescue medication more than placebo ( P < 0.05 for all comparisons ) .
