Greatest percent suppression ( 95 % confidence interval ) of 9:00 AM cortisol with budesonide was observed with MDI alone ( 73 % [ 57 to 90 ] ) and turbohaler ( 72 % [ 58 to 86 ] ) compared with MDI spacer ( 42 % [ 22 to 64 ] ) and oral administration ( 14 % [ +6 - to -34 ] ) .
