Improvement in mean disease activity index score was significantly greater with suppositories compared with oral mesalazine , both at two-week and four-week visits ( mean disease activity index scores at baseline , two , and four weeks : suppositories = 7.7 , 2.59 , and 1.48 ; tablets = 7.42 , 5.72 , and 3.48 , respectively ( P < 0.001 ) ) .
