A total of 123 patients were randomly assigned to receive gemcitabine ( 1000 mg per square meter of body-surface area ) and carboplatin ( at a dose equivalent to an area under the concentration-time curve of 2 ) on days 1 and 8 -- with or without iniparib ( at a dose of 5.6 mg per kilogram of body weight ) on days 1 , 4 , 8 , and 11 -- every 21 days .
