In contrast , pioglitazone enhanced ( P < 0.01 ) insulin-induced suppression of both glucose production ( 6.0 + / - 1.0 vs. 0.2 + / - 1.6 micromol x kg ( -1 ) x min ( -1 ) ) and gluconeogenesis ( n = 11 ; 4.5 + / - 0.9 vs. 0.8 + / - 1.2 micromol x kg ( -1 ) x min ( -1 ) ) .
