Severe pre-eclampsia developed in four women in the aspirin group and eleven women in the placebo group ( OR 0.24 , CI 0.07-0 .88 , P = 0.03 ) and intrauterine growth retardation occurred in eight cases in the aspirin group and twelve in the placebo group ( OR 0.49 , CI 0.17-1 .47 ) .
