This study compares three intensification approaches : changing insulin glargine to preprandial AIR inhaled insulin ( developed by Alkermes , Inc. [ Cambridge , MA ] and Eli Lilly and Company [ Indianapolis , IN ] ; AIR is a registered trademark of Alkermes , Inc. ) , intensifying glargine via validated titration algorithms ( IG ) , or adding AIR insulin while intensifying glargine ( AIR + IG ) .
