Fifty-nine volunteers ( 18 smokers : 8 with the S1S1 genotype , and 10 with the S2 allele ; 41 non-smokers : 29 with the S1S1 genotype and 12 with the S1S2 genotype ) consecutively followed three different diets : a diet enriched in saturated fatty acids ( SFA ) ( 38 % fat , 20 % SFA ) followed by a randomised , cross-over period during which they ate a diet enriched in carbohydrates ( NCEP-1 ) ( 30 % fat , 10 % SFA , 55 % carbohydrates ) and a diet enriched in monounsaturated fatty acids ( MUFA ) ( 8 % fat , 22 % MUFA ) .
