Carvedilol ( 0.4 mg/kg/d in children < or = 62.5 kg or 25 mg/d in children > 62.5 kg ) was associated with significant decreases from baseline in systolic BP ( 130 [ 4 ] vs 123 [ 3 ] mm Hg ; P < 0.05 ) , diastolic BP ( 85 [ 4 ] vs 77 [ 4 ] mm Hg ; P < 0.05 ) , and HR ( 81 [ 4 ] vs 65 [ 4 ] bpm ; P < 0.001 ) after the first month of addition to standard therapy .
