Methylphenidate administration resulted in a statistically significant increase in pulse of 12.3 beats/min ( 95 % confidence interval ( CI ) 9.25-15 .36 ) , diastolic blood pressure of 4.1 mmHg ( 95 % CI 2.11-6 .10 ) , and mean arterial pressure of 3.75 mmHg ( 95 % CI 1.79-5 .72 ) .
