This prospective , randomized , open-label , multicenter , community-based study was conducted to compare cyclobenzaprine 5 mg three times daily ( TID ) orally ( CYC5 ) given for 7 days as monotherapy or in combination with ibuprofen 400 mg TID ( CYC5/IBU400 ) or 800 mg TID ( CYC5/IBU800 ) in adults with acute neck or back pain with muscle spasm .
