One-hundred and eighty-nine subjects with plasma HIV-1 RNA levels between 400 and 100,000 copies/ml and stable ART ( > or = 8 weeks ) were randomized ( 2 : 2 : 2 : 1 ratio ) to add TDF 75 mg , 150 mg , or 300 mg or placebo to existing ART in a double-blinded manner .
