Efficacy outcome measures that were assessed at the beginning of the investigation and after 90 and 180 days of treatment included scores of the Alzheimer 's Disease Assessment Scale-Cognitive Subscale ( ADAS-Cog ) , the Mini-Mental State Examination ( MMSE ) , the Global Deterioration Scale ( GDS ) , the Alzheimer 's Disease Assessment Scale-Behavioral Subscale ( ADAS-Behav ) , all items of the Alzheimer 's Disease Assessment Scale ( ADAS-Total ) , and the Clinical Global Impression ( CGI ) scale .
