Two hundred nine patients with active RA were treated with escalating doses of MTX ( 5-15 mg/week ) , AZA ( 50-150 mg/day ) , or combination ( 5mg MTX/week plus 50 mg AZA/day -7.5 mg MTX/week plus 100 mg AZA/day ) , with opportunity to increase the dosage at 6-week intervals .
