Subjects with the most common genotype combination of the following four SNPs , -604 G/A , -501 A/C , Leu72Met , and Gln90Leu , had the lowest systolic ( 131 + / -11 v 137 + / -13 mm Hg , P = .003 ) and diastolic BP levels ( 79 + / -7 v 83 + / -7 mm Hg , P = .004 ) at the baseline of the study and during 3 years of follow-up compared to all other genotypes .
