In an intention-to-treat analysis , active treatment was associated with a 30 % reduction in the rate of fatal or nonfatal stroke ( 95 % confidence interval [ CI ] , -1 to 51 ; P = 0.06 ) , a 39 % reduction in the rate of death from stroke ( 95 % CI , 1 to 62 ; P = 0.05 ) , a 21 % reduction in the rate of death from any cause ( 95 % CI , 4 to 35 ; P = 0.02 ) , a 23 % reduction in the rate of death from cardiovascular causes ( 95 % CI , -1 to 40 ; P = 0.06 ) , and a 64 % reduction in the rate of heart failure ( 95 % CI , 42 to 78 ; P < 0.001 ) .
