In the primary analysis , duloxetine ( mean 78.7 mg/day ) was superior to placebo in reducing weekly frequency of binge eating days ( p = .04 ) , binge eating episodes ( p = .02 ) , weight ( p = .04 ) , and Clinical Global Impression-Severity of Illness ratings for binge eating ( p = .02 ) and depressive disorders ( p = .01 ) .
