Other PK parameters of ER and IR formulations were as follows : median tmax were 4.8 h and 2.0 h , Css-max were 20.21 2.69 mg/l and 19.71 3.46 mg/l , Css-min were 2.47 0.99 mg/l and 2.48 0.99 mg/l , Cav were 9.08 1.71 mg/l and 8.31 1.56 mg/l , respectively .
