A 12-week randomized , double-blind study in which hypertensive patients earlier uncontrolled ( mean sitting systolic BP150 and < 200 mmHg ) on angiotensin receptor blocker monotherapy ( other than valsartan ) after 28 days or more ( N = 728 ) were randomized to amlodipine/valsartan treatment [ 10/320 mg ( intensive ) or 5/160 mg ( moderate ) ] .
