A supplemental analysis of data from the subset of 41 patients in the ITT population with high carbohydrate craving ( 26 CrPic , 15 placebo ; mean BMI = 31.1 ) showed that the CrPic patients had significantly greater response on total HAM-D-29 scores than the placebo group ( 65 % vs. 33 % ; p < 0.05 ) as well as significantly greater improvements on the following HAM-D-29 items : appetite increase , increased eating , carbohydrate craving , and genital symptoms ( e.g. , level of libido ) .
