The mean decrease in ADAS-Cog score in patients treated with CA was 2.42 points after 90 days of treatment and 3.20 points at the end of the study ( day 180 ) ( P < 0.001 vs baseline for both ) , whereas in patients receiving placebo the mean increase in ADAS-Cog score was 0.36 point < 1 after 90 days of treatment and 2.90 points after 180 days of treatment ( P < 0.001 vs baseline ) .
