At 6 months , there was little difference between the acyclovir and placebo arms for cervico-vaginal HIV-1 RNA detection ( 88 [ 41 .3 % ] of 213 vs 84 [ 44 .0 % ] of 191 ; odds ratio [ OR ] , 0.90 ; 95 % confidence interval [ CI ] , 0.60-1 .33 ) , HSV DNA detection ( 20 [ 9 .4 % ] of 213 vs 22 [ 11 .5 % ] of 191 ; OR , 0.80 ; 95 % CI , 0.42-1 .51 ) , genital HIV or HSV loads , or plasma HIV-1 RNA load .
