Primary outcome was lower in the combined therapy than in the anticoagulant arm in both the intermediate - ( hazard ratio [ HR ] 0.33 [ 95 % confidence interval ( CI ) 0.12 to 0.91 ] ; p = 0.02 ) and the high-risk group ( HR 0.51 [ 95 % CI 0.27 to 0.96 ] ; p = 0.03 ) .
