Patients were randomized to 1 of 4 dosing cohorts : 1 ) 30 mg/m , 100 mg ; 2 ) 36 mg/m , 100 mg ; 3 ) 30 mg/m , 150 mg ; or 4 ) 36 mg/m , 150 mg of DTX intravenously weekly , LNF orally twice daily , respectively .
