We enrolled 79 healthy postmenopausal women ( mean [ + / - SD ] age , 56 + / - 4 years ) and randomly assigned them to receive continuous estrogen/progestin therapy ( n = 26 ; 17beta-estradiol [ 1 mg/d ] combined with norethisterone acetate [ 0.5 mg/d ] ) , genistein ( n = 27 ; 54 mg/d ) , or placebo ( n = 26 ) .
