Controlled for factors associated with diabetes risk , continuous antidepressant use compared with no use was associated with diabetes risk in the placebo ( adjusted hazard ratio 2.34 [ 95 % CI 1.32-4 .15 ] ) and lifestyle ( 2.48 [ 1.45-4 .22 ] ) arms , but not in the metformin arm ( 0.55 [ 0.25-1 .19 ] ) .
