During multiple-dose administration , there were no clinically relevant interethnic differences in fingolimod accumulation ratios ( 6.6 + / - 0.4 for whites , 7.0 + / - 0.7 for Asians ) , area under the concentration-time curve ( 390 + / - 73 versus 382 + / - 106 ng x h/ml ) , or elimination half-life ( 7.4 + / - 0.8 versus 7.9 + / - 2.0 days ) .
