Volunteers received darunavir 400 mg bid and darunavir 400 mg bid plus ketoconazole 200 mg bid , in two sessions ( Panel 1 ) , or darunavir/ritonavir 400/100 mg bid , ketoconazole 200 mg bid and darunavir/ritonavir 400/100 mg bid plus ketoconazole 200 mg bid , over three sessions ( Panel 2 ) .
