In an intent-to-treat analysis , carrying the last observation forward for all randomly assigned participants with at least 1 postbaseline assessment , the combination group lost more body weight than the zonisamide group ( mean [ SE ] = 7.2 [ 1.2 ] kg [ 7.5 % ] vs. 2.9 [ 0.7 ] kg [ 3.1 % ] ; F = 4.7 , df = 4,56 ; p = .003 ) during the 12-week period .
