Total symptom score and levels of total immunoglobulin E ( IgE ) , albumin , interferon ( IFN ) - , tumor necrosis factor ( TNF ) - , interleukin ( IL ) -10 , IL-4 , and IL-13 were measured in the serum and nasal samples of thirty non-atopic healthy controls and thirty patients with allergic rhinitis before and after 15 months of IT .
