The least squares mean CFA change in the double-blind phase was significantly greater with pancreatin vs. placebo : 21.4 % ( 95 % CI : 13.7 , 29.2 ) vs. -4.2 % ( -12.8 , 4.5 ) ; difference 25.6 % ( 13.9 , 37.3 ) , P < 0.001 .
