Considering the follow-up period as a whole , AFS and OS did not differ between treatments but for patients surviving beyond 2 years from randomisation , bypass was associated with reduced HRs for AFS ( HR 0.85 ; 95 % CI 0.50 to 1.07 ; p = 0.108 ) and OS ( HR 0.61 ; 95 % CI 0.50 to 0.75 ; p = 0.009 ) , equating to an increase in restricted mean OS of 7.3 months ( p = 0.02 ) and AFS of 5.9 months ( p = 0.06 ) during the subsequent follow-up period .
