In the operating room , midazolam 2 mg IV , compared with the placebo , produced a significantly greater increase in patients ' level of sedation ( 7 + / - 13 mm to 49 + / - 21 mm for midazolam vs. 8 + / - 11 mm to 19 + / - 21 mm for the placebo ; p less than 0.01 ) and a greater decrease in anxiety level ( 62 + / - 25 mm to 21 + / - 21 mm for midazolam vs. 54 + / - 27 mm to 53 + / - 22 mm for the placebo ; p less than 0.01 ) .
