آنزیمها را براساس که کاتالیز میکنند طبق شماره کمیسیون آنزیم (EC number) شماره گذاری میکنند
 
 
 
 
 
 
 
 
 
 1.1 گروه:EC 1.1 (act on the CH-OH group of donors)
 1.2 گروه:EC 1.2 (act on the aldehyde or oxo group of donors)
 1.3 گروه:EC 1.3 (act on the CH-CH group of donors)
 1.4 گروه:EC 1.4 (act on the CH-NH2 group of donors)
 1.5 گروه:EC 1.5 (act on CH-NH group of donors)
 1.6 گروه:EC 1.6 (act on NADH or NADPH)
 1.7 گروه:EC 1.7 (act on other nitrogenous compounds as donors)
 1.8 گروه:EC 1.8 (act on a sulfur group of donors)
 1.9 گروه:EC 1.9 (act on a heme group of donors)
 1.10 گروه:EC 1.10 (act on diphenols and related substances as donors)
 1.11 گروه:EC 1.11 (act on peroxide as an acceptor -- peroxidases)
 1.12 گروه:EC 1.12 (act on hydrogen as a donor)
 1.13 گروه:EC 1.13 (act on single donors with incorporation of molecular oxygen)
 1.14 گروه:EC 1.14 (act on paired donors with incorporation of molecular oxygen)
 1.15 گروه:EC 1.15 (act on superoxide radicals as acceptors)
 1.16 گروه:EC 1.16 (oxidize metal ions)
 1.17 گروه:EC 1.17 (act on CH or CH2 groups)
 1.18 گروه:EC 1.18 (act on iron-sulfur proteins as donors)
 1.19 گروه:EC 1.19 (act on reduced flavodoxin as donor)
 1.20 گروه:EC 1.20 (act on phosphorus or arsenic as donors)
 1.21 گروه:EC 1.21 (act on X-H and Y-H to form an X-Y bond)
 1.22 گروه:EC 1.97 (other oxidoreductases)
 2.1 گروه:EC 2.1 (transfer one-carbon groups, Methylase)
 2.2 گروه:EC 2.2 (transfer aldehyde or ketone groups)
 2.3 گروه:EC 2.3 (acyltransferases)
 2.4 گروه:EC 2.4 (glycosyltransferases)
 2.5 گروه:EC 2.5 (transfer alkyl or aryl groups, other than methyl groups)
 2.6 گروه:EC 2.6 (transfer nitrogenous groups)
 2.7 گروه:EC 2.7 (transfer phosphorus-containing groups)
 2.8 گروه:EC 2.8 (transfer sulfur-containing groups)
 2.9 گروه:EC 2.9 (transfer selenium-containing groups)
 3.1 گروه:EC 3.1 (act on ester bonds)
 3.2 گروه:EC 3.2 (act on sugars - glycosylases)
 3. گروه:EC 3.3 (act on ether bonds)
 3.4 گروه:EC 3.4 (act on peptide bonds - Peptidase)
 3.5 گروه:EC 3.5 (act on carbon-nitrogen bonds, other than peptide bonds)
 3.6 گروه:EC 3.6 (act on acid anhydrides)
 3.7 گروه:EC 3.7 (act on carbon-carbon bonds)
 3.8 گروه:EC 3.8 (act on halide bonds)
 3.9 گروه:EC 3.9 (act on phosphorus-nitrogen bonds)
 3.10 گروه:EC 3.10 (act on sulfur-nitrogen bonds)
 3.11 گروه:EC 3.11 (act on carbon-phosphorus bonds)
 3.12 گروه:EC 3.12 (act on sulfur-sulfur bonds)
 3.13 گروه:EC 3.13 (act on carbon-sulfur bonds)
 4.1 گروه EC 4.1 : (carbon-carbon lyases)
 4.2 گروه:EC 4.2 (carbon-oxygen lyases)
 4.3 گروه:EC 4.3 (carbon-nitrogen lyases)
 4.4 گروه:EC 4.4 (carbon-sulfur lyases)
 4.5 گروه:EC 4.5 (carbon-halide lyases)
 4.6 گروه:EC 4.6 (phosphorus-oxygen lyases)
 5.1 گروه:EC 5.1 (racemases and epimerases)
 5.2 گروه:EC 5.2 (cis-trans-isomerases)
 5.3 گروه:EC 5.3 (intramolecular oxidoreductases)
 5.4 گروه:EC 5.4 (intramolecular transferases -- mutases)
 5.5 گروه:EC 5.5 (intramolecular lyases)
 5.6 گروه:EC 5.99 (other isomerases)
 6.1 گروه:EC 6.1 (form carbon-oxygen bonds)
 6.2 گروه:EC 6.2 (form carbon-sulfur bonds)
 6.3 گروه:EC 6.3 (form carbon-nitrogen bonds)
 6.4 گروه:EC 6.4 (form carbon-carbon bonds)
 6.5 گروه:EC 6.5 (form phosphoric ester bonds)
 6.6 گروه:EC 6.6 (form nitrogen-metal bonds)
 برخی از آنزیم‌های مهم عبارتند از:
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