This is one of the books that we we're looking into for book club, and I have to say I enjoyed it much more than Ape House by Sara Gruen, (another we had purchased last year). For me there was plenty to discuss, not just about the book and it's characters but also the ethics surrounding animal testing etc. I struggled at times with descriptions and this is another book that has made me think more about how we treat animals, each other and our world in general. 
 I enjoyed the unconventional narration of the story, one thing I would've like to have see was more than one narrator - possibly from Lowell's perspective. Because it is all from Rosemary's perspective I feel like there were times when it would've benefited from someone else viewpoint. I think Rosemary starting in the middle was essential. I agree, knowing certain elements before that would've changed my feelings about the story. Overall, on the surface this was an easy, fast paced read. But ultimately one which made me think about a subject matter that is not entirely comfortable to discuss.