Fast paced speculative fiction. Y the last man starts when all the men in the world suddenly squirt blood from the various bodily orifices and slump to the ground. Stone dead. Of course, one man survives. As the title helpfully implies. 
 The story relies more on the compulsion of a crime novel and not too much on philosophical introspection a la 'Watchmen'. There are no monologues and intellectual back-and-forths on the deeper nature of the universe, power, life etc. At least not yet. So far, from page one you are hit with action that doesn't stop. In that sense it reminds me of Tintin. 
 But now that i think of it, Yurik, the protagonist does share some of the characteristics of Tintin. He's young, brash, idealistic and even has a pet (though the pet here is the improbably named monkey Ampersand). But while Tintin shows maturity and cunning born of years of experience, Yurik is young and naive. And this also gets him into a lot of trouble. Probably the point, as his misadventures help the story along. 
 48% of the worlds population die from the plague. 99% of government representatives, construction workers, religious leaders, soldiers and members of numerous other professions (except agriculture, where 51% of workers are women) are dead. Undoubtedly this is a perfect setting to take a dig at feminism and ideas of patriarchy, and Vaughan does that with gusto. 
 IMO all feminists should read this book. Vaughan's female-only society is filled with irony. His cast of females include fierce 'Amazons', Republican terrorists, war thirsty Israli soldiers, supermodels turned garbage collectors, secret agents, hobos, wannabe rock stars and the all important scientist. He takes patriarchy and turns it inside out. This is speculative fiction at its best. 
 The first volume is only about one tenth of the whole story, still it looks promising. His explorations of power structures i found particularly interesting. The political undertones are also worth noting.