Updated 11/2014: 2nd time around, via audio, and I absolutely loved it! Charles and Anna are terrific characters, and their relationship and their adventures are fascinating. 
 My review from my 1st read (2012): 
 Fine literature this is not, but boy, am I enjoying this series! I stumbled across the "Alpha & Omega" series by Patricia Briggs by chance, almost read them out of order, corrected myself, and have now read the original novella and three subsequent novels. Apparently, this series is a spin-off from the author's Mercy Thompson series... which I had never heard of, but now realize is a very popular and successful urban fantasy series. 
 Fair Game continues the story of Charles and Anna, mated werewolves as well as human husband and wife. Their love story is actually surprisingly moving, and while their history is more fully explored in the earlier books in the series, their relationship continues to play out in Fair Game in new and interesting ways. Charles and Anna are unique characters, each fascinating in their mix of power and vulnerability. I love the insights into pack dynamics that the author provides through each new volume in the series, and the broadening of their world to include other types of supernatural powers and entities. 
 Fair Game is constructed around the hunt for a serial killer who preys on supernatural as well as human victims. The murder mystery itself was engaging and had some good solid twists (although I pegged the killer pretty early on, so perhaps it wasn't really all that mysterious). 
 Overall, Patricia Briggs does a great job in Fair Game of balancing character development and growth with a police procedural plot. I was completely engrossed and couldn't put the book down. I can't wait for the next one! Meanwhile, I think I'll give Mercy Thompson a try.