One reason why I would want to be immortal - I would be able to read all the books. One reason why I would not want to be immortal - watching my family and friends die would suck. 
 Pia is the lynchpin of a new immortal race. And this is all she knows. Literally. In order to keep Pia in line they only teach her what she needs to know, which is everything about science and elysia (what gave her the immortality) and nothing about the real world. She's never even seen a map of the world. Even though she doesn't realize it she is a prisoner, she's never left Little Cam. 
 While at times Pia could be a little annoying I did feel sorry for her. Everyone at Little Cam kept calling her perfect. It would be enough to give anyone a complex. Many of the scientists treated her like a god because of her immortality. It was nice to see her struggle with immortality and what it meant for her. 
 Uncle Paulo was the worst! He was the super crazy scientist that let everything go way too far. At one point in the book he even calls himself a god. And you know what happens when people try to play God... There were other crazy scientists too, though none as crazy as Uncle Paulo. They were very dedicated to their cause and it was a little disconcerting. 
 Aunt Harriet was my favorite character. She recently came from the outside and liked to do things her way. She was the one person who would be honest with Pia. 
 Eio was an Ai'oan, the indigenous people that lived near Little Cam. The Ai'oan's were so much better than the scientists. I enjoyed reading about Pia's adventures with them much more than what happened inside the compound. The connection between Pia and Eio felt a little forced at times. There weren't a whole lot of feelings in this book. It was more they met, they are going to be together, the end. 
 At times Origin was a little too sciency for me. A lot of science words were tossed around in the beginning. The concept of how someone is made immortal is a little complex but not over the top. How the elixir is made is a little over the top for me, but science lovers probably won't think so. 
 There were some surprises along the way but the ending was a little obvious. There was really only two ways it could go and the probability was high that it would go the way it did. I might have actually liked it a little more if it would have gone the other way because it would have been different.