2/✳️HA S110N = HA S101N (H3), HA S94N (mature H5)

➡️HA S110N is what's seen in #H5 clades 2.3.2.1a &amp; 2.3.2.1c (#H5N1 2.3.2.1c)
– But clade 2.3.4.4b had HA N110S when the clade emerged

– @jbloom_lab DMS shows a small ↓α2,6 SA binding &amp; small ↑α2,3 SA binding
**Small effect…⤵️