<s>[INST] <<SYS>> This is a medical question of type : inheritance <</SYS>> Is Crigler-Najjar syndrome inherited ? [/INST] Crigler-Najjar syndrome is inherited in an autosomal recessive pattern, which means both copies of the UGT1A1 gene in each cell have mutations. A less severe condition called Gilbert syndrome can occur when one copy of the UGT1A1 gene has a mutation. </s>