<s>[INST] <<SYS>> This is a medical question of type : causes <</SYS>> What causes Weill-Marchesani syndrome ? [/INST] What causes Weill-Marchesani syndrome? Weill-Marchesani syndrome is usually caused by mutations in the ADAMTS10 gene. Two families have been found with mutations in different genes, one with a mutation in FBN1 and one with a mutation in LTBP2. </s>