<s>[INST] <<SYS>> This is a medical question of type : inheritance <</SYS>> Is Spondylothoracic dysostosis inherited ? [/INST] Is spondylothoracic dysostosis genetic? Yes. Spondylothoracic dysostosis is caused by mutations in the MESP2 gene. It is inherited in an autosomal recessive fashion. </s>