<s>[INST] <<SYS>> This is a medical question of type : exams and tests <</SYS>> How to diagnose Mixed connective tissue disease ? [/INST] How is mixed connective tissue disease diagnosed? Mixed connective tissue disease (MCTD) is often suspected after a physical examination reveals signs and symptoms associated with the condition. The diagnosis is supported by a blood test that shows high levels of antibodies associated with MCTD. </s>