<s>[INST] <<SYS>> This is a medical question of type : frequency <</SYS>> How many people are affected by acatalasemia ? [/INST] More than 100 cases of acatalasemia have been reported in the medical literature. Researchers estimate that the condition occurs in about 1 in 12,500 people in Japan, 1 in 20,000 people in Hungary, and 1 in 25,000 people in Switzerland. The prevalence of acatalasemia in other populations is unknown. </s>