<s>[INST] <<SYS>> This is a medical question of type : frequency <</SYS>> How many people are affected by limb-girdle muscular dystrophy ? [/INST] It is difficult to determine the prevalence of limb-girdle muscular dystrophy because its features vary and overlap with those of other muscle disorders. Prevalence estimates range from 1 in 14,500 to 1 in 123,000 individuals. </s>