<s>[INST] <<SYS>> This is a medical question of type : inheritance <</SYS>> Is Acute intermittent porphyria inherited ? [/INST] How is acute intermittent porphyria (AIP) inherited? AIP is inherited in an autosomal dominant fashion, which means only one of the two HMBS genes needs to have a disease-causing mutation to decrease enzyme activity and cause symptoms. </s>