<s>[INST] <<SYS>> This is a medical question of type : frequency <</SYS>> How many people are affected by cytogenetically normal acute myeloid leukemia ? [/INST] Acute myeloid leukemia occurs in approximately 3.5 per 100,000 individuals each year. Forty to 50 percent of people with acute myeloid leukemia have CN-AML. </s>