<s>[INST] <<SYS>> This is a medical question of type : outlook <</SYS>> What is the outlook for Multiple System Atrophy with Orthostatic Hypotension ? [/INST] Most individuals with multiple system atrophy with orthostatic hypotension die within 7 to 10 years after the onset of symptoms. A problem with the respiratory system is the most common cause of death. </s>