<s>[INST] <<SYS>> This is a medical question of type : frequency <</SYS>> How many people are affected by Manitoba oculotrichoanal syndrome ? [/INST] Manitoba oculotrichoanal syndrome is estimated to occur in 2 to 6 in 1,000 people in a small isolated Ojibway-Cree community in northern Manitoba, Canada. Although this region has the highest incidence of the condition, it has also been diagnosed in a few people from other parts of the world. </s>