<s>[INST] <<SYS>> This is a medical question of type : outlook <</SYS>> What is the outlook for Adrenoleukodystrophy ? [/INST] Prognosis for patients with childhood cerebral X-ALD is generally poor due to progressive neurological deterioration unless bone marrow transplantation is performed early. Death usually occurs within 1 to 10 years after the onset of symptoms. Adult-onset AMN will progress over decades. </s>