<s>[INST] <<SYS>> This is a medical question of type : outlook <</SYS>> What is the outlook for Ataxia Telangiectasia ? [/INST] Average lifespan has been improving for years, for unknown reasons, and varies with the severity of the underlying mutations, ATM (ataxia-telangiectasia mutated) protein levels, and residual ATM kinase activity. Some individuals with later onset of disease and slower progression survive into their 50s. </s>