<s>[INST] <<SYS>> This is a medical question of type : frequency <</SYS>> How many people are affected by propionic acidemia ? [/INST] Propionic acidemia affects about 1 in 100,000 people in the United States. The condition appears to be more common in several populations worldwide, including the Inuit population of Greenland, some Amish communities, and Saudi Arabians. </s>