Yes, the fibroblasts of skin cells can quite easily be Transfected with a fluorescent gene such as GFP. Fluorescence doesn't actually produce light, the fluorescent molecule just changes the wavelength of light shining on it. 

Fibroblasts can also be made luminescent (light producing) by acquiring  genes for firefly luciferase or aquoren from jellyfish. This is a little more tricky since luminescent molecules typically require cofactors such as ATP, Calcium or other proteins.

Both methodologies are readily performed in vitro.

Can a portion of human skin cells be modified in some way to generate light?
Since System76 is the largest vendor for consumer PCs with Ubuntu pre-installed, are questions about their products allowed if they don't concern the OS in particular? That would include


What usb3 or e-stata drives actually work with their laptops
What peripherals work with particular system76 machines.
How/should I upgrade the BIOS?

