Meeting with a heavy loss in an honest little enterprise in which all the loss was intended to have been on the other side, he broke something--something necessary to his existence, therefore it couldn't have been his heart--and made an end of his career. 
Meeting with a heavy loss in an honest little enterprise in which all the loss was intended to have been on the other side, he broke something - it couldn't have been his heart - and made an end of his career.
