<s>[INST] hi my husband takes prodep 10mg and he not finding it useful at all...he increased to 20 mg but is keeping him awake the whole nite..this is for general anxiety and negative thoughts...is there any other mediaction...pls dont rite anything negative cos it gives me more negative tohughts [/INST] Hi, thank you for using Chat Doctor. I can understand your concern. Prodep 20 not helping in general anxiety is not an end. There are lots of other medicines like sertraline, Escitalopram, clomipramine, buspirone, benzodiazepines which can helpful in your husbands condition. Take consultation of psychiatrist who will be able to assess your husbands condition more accurately and able to guide you people out of this. I hope this will help you. Regards. </s>