<s>[INST] Hi doctor, M suffering from mesangial proliferative glomerular nephritis from 2008. 3times Itreated with prednisolone but its not fully treat me than after I treated with cyclosporine but this time also no fully treated me. What is your opinion for my future Can Ifully treated? Can Ilive a normal healthy life? [/INST] Hi, welcome to Chat Doctor. Mesangioproliferative GN require immunosuppressants for treatment. It is necessary to rule out common disease that can present with this pattern. Lupus, IG A Nephropathy, hepatitis b and c infection. Treatment protocol is different for these diseases.it is necessary to continue meds for long sometime. Mycophenolate can be helpful in this situation. You can discuss this with your nephrologist, or you can communicate with me also with above reports and previous detailed reports. I think this would be helpful to you. Best wishes. Tc.  Chat Doctor.  </s>