<s>[INST] Hi doctor, My son is a doctor and he 36 years now. He had burping and tightness of the chest. Cardiologist did stress test and blood tests. Non sure indication of blockage. But suspicious and have decided to do angigram and said that if that is negative he wants to do MRI on the brain. What is the connection between chest tightness and brain MRI? The last 2 procedures are planned for next few days. Saravana [/INST] Thanks for your question on Chat Doctor. I can understand your sons situation and problem. I don't find any relevant connection between chest tightness and brain pathology. By his history and description, possibility of HERD (gastroesophageal reflux disease) is more. It is due to laxity of gastroesophageal sphincter. Because of this the acid of the stomach tends to come up in the esophagus and cause the symptoms of Central burning chest pain, burping, chest tightness, pressure etc. Better to rule out cardiac diseases first. So no harm in doing Angiography. But before MRI brain, discuss with doctors about possibility of HERD. He may improve with proton pump inhibitors and prokinetic Chat Doctor.  Ask him to avoid stress and tension. Avoid hot and spicy food. Don't worry, he will be alright. Hope I have solved your query. Wishing good health to your son. Thanks. </s>