<s>[INST] Hi, is there anything that can be done about reduced penile sensitivity? Orgasms through masturbation have become more difficult, now to the point where it is almost impossible unless I am very aroused. With a woman I also have a hard time having an orgasm. In either case I can get a strong and hard erection and can keep on going for a long time (much to the pleasure of my partner....) [/INST] HiT hank you for asking Chat Doctor. I have gone through your query. Anesthetic or condom with anesthetic will help you decrease sensitivity and prolong ejaculation time. SSRIs like paroxetine or duloxetine also used for some. Duloxetine can be used in need (SOS) also. But initially you can try squeeze and stop technique and if that not working can go for behavioral therapy. Hope this may help you. Let me know if you have any further queries. Thanks </s>