<s>[INST] Hi, I am a 24 year old who has recently been diagnosed with pCOS, the doctors put me on Triquilar for 3 moths but the problem did not resolve now they are asking me to use primolut for 3 months, is it safe since Im trying to conceive. I am 153cm and weight 81.5kg and I dont have any medical history. [/INST] Hi, How are you doing ? POD (Polycystic ovaries), This is a congenital condition, I mean it is a genetically programmed condition, you get it from your parents. When you suddenly put on weight, this cholesterol is converted into estrogen hormone (if I may simulate- haven't you have seen obese men developing breast & in young obese girls, who develop periods at younger age - they all have high levels of Estrogen hormone / female hormone) In your body too when fat, which is a store for tomorrow, is more than normal, this is converted to hormone which tips the balance between FSH (from brain) & the ovarian hormone. FSH(Follicle Stimulating Hormone) as name suggests stimulates follicle from ovary, but once the follicle is big enough to ovulate, the FSH is suppressed by the same estrogen hormone from ovary. But when the same estrogen hormone is coming from fat, brain is confused & follicle growth stops early at a smaller follicle size & will not rupture, next scan you will see all these follicles as POLY CYSTIC OVARIES.!!! This is usually associated with Obesity, irregular cycles, no periods for few months & later heavy periods with clots & fleshy masses, or spotting on & off, Thyroid abnormality & prolactin problem indirectly. You develop that extra-pad of fat around the midsegment of body, especially waist, thighs & breast, no fat beyond elbow & knees. Excessive body hair growth, hair fall, dark shade over lower half of face, acne, oily face skin, black skin over back of neck, inner thighs & under surface of breast. May have a family history of Diabetes, especially father or his family. This will not allow ovulation to occur at time & so you cannot get pregnant, till treated. It also increases your chances of early pregnancy abortions. But this has a solution. Your weight has to be Weight(in Kg)= Height (in CMS)-100Your expected weight is 53-58 kg. Once you reduce weight to normal range, you won't need any medicine to get periods or to get pregnant & pregnancy will be healthy. To reduce weight -NO FASTING, No junk food/ fast foods/ red meat, reduce snacks in between mealsHave low calories' food, high proteinsRegular exercise (especially for the waist & hip area), aerobics, yoga, brisk walking(swing your hands well) ,try to reduce 2-4 kg / month. Don't hurry on weight reduction, it will be difficult to maintain. As soon as you reduce at least 5 kg, you will see changes. When you take Primolut-N only your periods get altered, does not do any good or bad to your pregnancy chances Hope I have clarified your queries. Do write back if anymore queries the best </s>