<s>[INST] a recent blood test showed psa levels at 14.3.Previous results...last 10 or more years have always shown "in range" results.This recent test was performed using the Siemans chemiluminescent method.The results showed 14.3.As mentioned previous results were always Age 59, weight is 155 consistent, no health problems.  In general, good health. [/INST] HelloThanks for query. Your recent PSA levels are reported to be 14.3.which is quite higher than normal value of 4. The PSA can get raised in following three conditions 1) Enlarged Prostate 2) Cancer of the prostate 3) Infection of the prostate However it is an international protocol and rule that high PSA is always suspected to be due to cancer of the prostate unless proved otherwise by doing ultrasound guided multi score prostate biopsy. Take antibiotics like Cefuroxime twice daily for 10 days and repeat PSA. If it is reported to be still higher than normal you will need to consult qualified Urologist for clinical and digital rectal examination and get following basic tests done to confirm the diagnosis.1) Urine routine and culture. 2) Ultrasound scanning of abdomen and pelvis and Trans Rectal Ultrasound scanning (THUS)3) Prostate biopsy (If he detects hard nodule on surface of prostate on digital rectal examination)Further treatment will depend upon final diagnosis Chat Doctor.  </s>