<s>[INST] Last night I experienced extreme pain in my lower abdomen and leg. I had been taking norethisterone for around 2-3 months and started randomly bleeding lightly last Sunday, still bleeding Saturday just past I stopped taking the tablets as not to waste them.  It felt like someone was twisting my insides last night I was sweating and nauseous and could not stop the pain with ibuprofen or heat and the pain just got worse at some point I must have passed out and awoke later drenched in sweat with the pain even more intense abdomen and leg so i got up and I noticed the bleeding had became worse and found a blood clot around the size of piece of liver the pain gradually disappeared but I feel like I have been kicked by a horse from the inside out and I still have some pain in my leg.  Was this a result of the pills? [/INST] Hi, The passage of the large clot may have caused the pain and the associated nausea and sweating. Prolonged use of estrogen or progesterone can result in several side effects including circulation disturbances like thrombosis of limb vessels and embolisms. Please contact your health care provider immediately for assistance. You should get blood counts, bleeding and clotting time along with a trans-vaginal/pelvic sonogram to look for local causes. You should stop taking the Chat Doctor.  Wish you good health. </s>