<s>[INST] My father has stage 4 liver cancer. He had done the TACE chemo ONCE but is not doing well especially when the cancer growth is progressive. Right now doctors are just giving him pain management because theres not much they can suggest. Is there anymore hope? [/INST] Hi, Thanks for writing in. TACE is transarterial chemo embolization and a method used to treat liver tumors from a closer distance. In RACE, a single or more than one cancer medicines are given into the hepatic artery and this causes the Chat Doctor.  However, it is unfortunate that your father has a tumor which did not respond to treatment. There is a new procedure called SIR(Selective internal radiation therapy) that can be given to patients who do not respond to RACE as a second line of treatment. This is not available in every hospital, and you can discuss with his doctor if this treatment is made available to patients in your place. Please note that stage 4 cancer might have an expected survival of up to two years with recommended treatment and good supportive care. Hope your father responds to treatment. Please do not worry. </s>