<s>[INST] Hi I am 25 years old. I had cold, sneezing,wezing for a long time. I took so many medicines. But i didnt get a relief. But now i am using Duonase nasal spray and Budamate 200. I feel beter now. 1. does this medicine have any side effect on long term use? [/INST] Hello, Like all medicines and Bedmate, Donate has side effects! Nausea, headache, dizziness, nervousness, Chat Doctor.  I think you should do a prick test, spirometry to evaluate your condition. These medications may be used in exacerbations of symptoms and if you feel better to consult with your doctor the possibility to take something else. Hope I have answered your query. Let me know if I can assist you further. Take care  </s>