<s>[INST] I am taking crestor 10 mg and once a day with hydroxychlor 200 mg two times a day and have muscle weakness in knees and and legs with charleyhorses where my legs are sore. I also take etodolac 400 mg two times day with azor 10-40 mg any good ideas thank you Thomas Walter [/INST] You must see treating doctor. Muscle weakness and pain may be related to medicines you are on. Sometimes, other causes may be there too like Vitamin B1,B6,B12 deficiency, calcium and vitamin D deficiency etc. which can be evaluated by blood test if your doctor considers. If you smoke or have excess alcohol, that may also need to cut on gradually. Next is blood sugar, obesity, overweight cause if any, to be screened for. </s>