<s>[INST] hi.... i am from india.....my wife is of 33 years & we are having a son of 4 years....we are married for 7.5 years.....both my wife & myself are working professionals..... my wife recently developed pigmentation on her face, sholder & arms.....a local doctor said that these may be due to consumption of dienne 35, which she regularly consumes for the last 4 years..... my question: is there any side effects of dienne 35, like pigmentation...? [/INST] Hi, Thanks for writing in. Dianne 35 is hormone based contraceptive it may cause pigmentation as a side effect. But pigmentation can occur due to variety of reason like lichen plans, post inflammatory, amyloidoisis etc. Proper examination is required for diagnosis of the cause. I encourage you take visit to a qualified dermatologist for examination and proper treatment. Visit a dermatologist for some clinic based procedure like chemical peeling and laser.  Hope this helps. Regards Chat Doctor.  </s>