<s>[INST] My dad has myelofibrosis. His platelet count is ridiculously low. His spleen is enlarged and he s been complaining his left side below his ribs are hurting. I think its his liver. His doctors are doing great but his pain keeps getting worse. He was diagnosed last April. Do you think with these signs he s getting close to the end? I dont want him to go but dont want him suffering either. Any info will help my family. Thank you [/INST] Hi, dairy have gone through your question. I can understand your concern. Myelofibrosis is one type of bone marrow cancer.  In that blood producing cells are replaced by fibrosis. Treatment options are stem cell transplantation.  Other options are splenectomy, an Chat Doctor.  Despite treatment prognosis remains poor. Life expectancy is not good. Consult your doctor and take treatment accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using Chat Doctor. Wish you a very good health. </s>