<s>[INST] I have been prescribed minitran for blood circulation to my foot, because of scleroderma ulcer by internationally known wound specialist dr. A Sibbald in toronto. All info says to avoid leg, he is out of country. Why not to leg?????? Also most pain is at nite and I am using it from 12pm to 12 am . Put on foot/leg as directed Carol farkas Phd [/INST] Hi, Thanks for asking. Based on your query, my opinion is as follows.1. Application to leg, possibly can cause vasodilation in the legs, leading onto pooling of blood and hypotension.2. Wait for your doctor to return before starting. If started, and if you have dizziness, need to avoid it.3. Helps in ulcer healing faster, can continue, if no side effects. Hope it helps. Any further queries, happy to help again. </s>