<s>[INST] I have had chronic fatigue, joint pain, water retention, depression and weight gain over the past year and a half.  I had my blood work done and my Prolactin level is at 52.3.  I will be having more blood work in about 6 weeks.  Could Prolactin be causing these problems?  Oh and I am only 32 years old, I shouldnt be feeling this bad. [/INST] Hello and welcome to Chat Doctor, The symptoms of chronic fatigue, joint pain, water retention and weight gain are not associated with high prolactin levels. High prolactin level is caused by increased secretion of prolactin by pituitary gland. Increased secretion of prolactin can be due to prolactin secreting tumor. The symptoms of fatigue, water retention, depression and weight gain are suggestive of disorders of thyroid gland. Hypothyroidism can lead to similar symptoms. Thus, thyroid function tests are required to assess the thyroid functions. Pituitary gland also needs to be examined by imaging study to look for any tumor of pituitary gland. Thanks and take care Chat Doctor.  </s>