<s>[INST] I am suffering from diabetes and ED and also premature ejaculation. I am taking Wosulin50/50, 16 units morning and 12 units eve along with met 50/500 1 mor and 1 eve for diabetes. my problem is i never have erection a bit since one year at least. I tried tadalafil 20 mg also tried Assurance 50 mg. Then I get erection and started premature ejaculation.Is there any med for both ED and Pre Ejaculation [/INST] HelloThanks for query. You are known diabetic and have been taking insulin and oral anti-diabetic medications. Assming that your diabetes is well controlled your problem of Ed seems to be basically due to diabetes. Since Calls in a dose of 20 mg has given satisfactory results you may take Duloxetine along with Calls. This will help you to have sustainable hard erection to have enjoyable sex and prevent premature ejaculation. Chat Doctor.  </s>