<s>[INST] I am 68 female 5 feet 170 pounds. Had red palms for about a year. Dermo said its nothing. Can you believe that.? Used many creams fungal and not. Seems like it is under the skin and very red, Not too itchy but hot. Worrying me alot. Coould it be serious. Had blood work done. Dr. changed my blood preasure meds cause said kidneys were a little off. Now it is ok with Amlodipine 5/40. Please help!!! Thank you [/INST] Hello! Welcome and thank you for asking on Chat Doctor! Your symptoms are compatible with a disorder called "Palmer erythema" in. This condition can be caused by various medical problems, each having its own range of severity. In a lot of patients, red palms have no identifiable cause, and they are presented under primary Palmer erythema. However, there are many cases in which the red palms are a symptom of another disease, being presented as secondary Palmer erythema. I would mention:-smoking and alcohol intake-high blood pressure-thyroid dysfunction-kidney or liver disorders-polycythemia vera-diabetes-rheumatological disorders, etc. I would recommend performing inflammation tests and thyroid hormone levels to exclude this possibility. Your renal function, may be related to it. But as, I mentioned before, in many cases, the cause can not be found even after a lot of tests. Hope you will find this answer helpful! Best wishes,  </s>