<s>[INST] Hi, I have a combination skin, which means oily on my t-zone and dry on cheeks . I take care of my face real good. I wash it every night with a gentle cleanser , I moisturize it, and whenever I get pimple or acne I use the acne medicine and it will disappear. But in the few past days I got some pimples and acnes which just dont go away! And whenever they disappear new ones come out! Why is that? What should I do? p.s. I do exercises, and I eat healthy. And I m 18. [/INST] Hi! Sue, Welcome to Chat Doctor forum, Sue you wrote that you clean your skin properly.that's good, but you also mentioned that you moisturize it ....well that not good tall...since you have acne prone skin you should not moisturize it. It an irony that you have a combination skin and still you get pimples.but that happens. So start with using an oil free face wash...you need to take tablets like azithromycin 500 mg once daily for 3 days for acne.apply anti acne gels regularly like nadifloxacin gel . Along with this you need to check your hormonal profile too, as imbalance in you periods can also be the cause of pimples... Hormone profile like LH/FSH ratio, SERUM TESTOSTERONE, DHEA-S needs to be done...this would give the clear picture of your hormones. At time one gets pimples two days prior to periods, which also means that hormones are responsible for pimples. If not you need a conventional treatment. Recently available is one of the best medicines for acne is isotretinoin which needs a dermatologists prescription.It's a wonder Chat Doctor.  Kindly consult a dermatologist for the same. Take care, </s>