<s>[INST] I am female 28 years. I have lupus nephritis stage 4. I am on cellcept 3000. I took one pill of immodium a few days ago to stop diarrhea since I was traveling by plane. I was throwing upon the plane. Since then I have some abdominal swelling and constipation . Could the immodium have affected my kidneys? What should I do? [/INST] Hi, it is unlikely that Imodium has affected your kidney. What is your serum creatinine level and has it recently increased. MMF can produce diarrhea and vomiting. Did you recently start the medicine of increase its dose? SHE can affect almost all body organs, what were your involvements at diagnosis and whether you are in remission or active disease. All this has to be considered to find out the cars of abdomen swelling and vomiting. You can follow up with your nephrologist, and he should be able to sort it out for you. </s>