<s>[INST] do Oxycodone pills have a life span? [/INST] Hello, All medicines come with expiration date. Beyond the expiration date, if the pills are taken, chances are there that they will not produce the desired effects or even worse, they may cause adverse reactions that can complicate the health status or cause complication. Thus, Oxycodone pills should not be taken if they have passed the expiration date, and you should go for a new prescription and batch of pills. I hope this answer helps you. Thank you for choosing Chat Doctor. Take care. Best, </s>