<s>[INST] My 54 year old boyfriend was put on Prozac for depression and not able to cope with job...it worked wonderfully and made him a different person. After several months sexual dysfunction appeared, the doctor switched him to Zoloft, that didn t work for the dysfunction and the wonderful feeling seemed to go away and couldn t sleep so he cut the pills in half. The doctor then switched him to Wellbutrin and don t know how that is going as he became quite agitated and became unsocial and un-talkative. Don t know how to help him because he keeps things inside that I might be able to help with. I have been on antidepressants for years and know you can t switch from one to another, stop taking them, start again then cut them in half. He is 6 3 and weights 240 pounds. What can he do? [/INST] Hello, Thanks for choosing Chat Doctor for posting your query. I have gone through your question in detail and I can understand what you are going through. Welbutrin can cause anxiety symptoms initially. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. In future if you wish to contact me directly, you can use the below-mentioned link:bit.ly/ Chat Doctor.  </s>