<s>[INST] I have been on Dian 35 on and off for about 15 years. I have has two bouts of major depression and I am on lyrica and lexapro for the past five years. I am 45 years old. I am now experiencing Utis. Could they be caused by dian 35 and could my anxiety and depression caused it too? Would you recommend that I come off Dian 35? [/INST] Hi there ~ Diane 35 is a contraceptive medication and will not cause Otis.  Anxiety and Depression are treated with Learn and Lyrics, however you need to understand that you should also consider if you are experiencing any changes in your symptoms of anxiety and depression that is making your lifestyle worse i.e. you are not Chat Doctor.  If that is the case then you might have had Otis indirectly due to that reason.  However, not good sexual or genital hygiene and deny </s>