<s>[INST] I have had a partial thyroidectomy due to a goiter removed and came back positive for Hashimoto`s. I was placed on synthroid .150mcg...I have TSH level of .005 and gaining weight while I am always exhausted. I also I have a pituitary tumor as well as diagnosed primary progressive MS witChatDoctorplication of kidney stones that caused obstructed kidney in the last two months that I still suffer flank pain from. where should i start to feel better..any clue? [/INST] Hello and welcome to ChatDoctorYou have mentioned that you have had partial thyroidectomy for goiter which turned out to be Hashimoto thyroiditis. After the surgery you should get your thyroid function tests regularly to rule out any abnormality of thyroid hormones. Regarding the pituitary tumor, it is important to know if there are any symptoms associated with the pituitary tumor. If there are symptoms surgical removal needs to be done. For this you will have to refer a neurologist. Primary Progressive Multiple Sclerosis is a progressive degenerative disorder in which there is destruction of myelin. In primary progressive MS the disease process is relapsing and remitting. During this stage certain medications help e.g. Interferons, polypeptides which protect the myelin and immunosuppress which prevent the destruction of myelin. These Chat Doctor. Lastly, about kidney stones you need to get it removed soon as it is causing obstruction. Before that get your urine examination and X-ray of the PUB region. Thanks and take care </s>