<s>[INST] I have anxiety and the past few says have had anxiety all day and a nauseous detached feeling..a feeling of my familiar spaces feeling different to me..I have been on Zoloft for about 10 years and haven t has this feeling for a really long time..what could cause this..is it anxiety? [/INST] Anxiety may cause this feeling of detachment from surrounding. Such feelings of unfamiliarity with surroundings are also seen in other conditions (such as migraine, with use of recreational Chat Doctor. In my practice, I often see these in patients of panic disorder and sometimes in migraines; treatment of these conditions gives relief from this symptom too. Zoloft is not likely to be the cause for this feeling. In my opinion, you should continue Zoloft and report the symptom, along with any other complaints you may have, to your doctor during your next appointment. I hope this answers your question. </s>