<s>[INST] My brother who is 22 years old has fever from 2 weeks and no other symptoms. We have done his blood tests and after 2 weeks typhoid is coming positive. He has already completed antibiotic course of Cefuroxime axetil but fever is not going done. He has to take crocin. Now Doctors has prescribed zenflox 14 days course. please suggest is this the right approach now [/INST] Hi, I have gone through your query and understand your concerns. I hope your treating physician had advised a battery of blood tests along with urine test also & out of these only typhoid test result is positive. If your brother has not been investigated for malaria and urine infection, then get him investigated also for the same. In my opinion Ofloxacin (Influx) is a good antibiotic for typhoid fever, apart from influx, Azithromycin, definite & ceftriaxone are other choice of Chat Doctor. It's been approx > 14 days since your brother is running fever, so I will suggest you to go for injectable antibiotics like Ceftriaxone, under physician supervision only. Till then I will suggest you to take Cronin if fever comes, along with cold sponging. Irrational use of antibiotics can result in resistance of organisms to the  </s>