<s>[INST] Liver function test results show all the components are normal but for bilirubin which is 1.8 against0.8.Further US scan result shows mild coarse echotexture liver but normal in size and no leisons etc. I am diagnised to be HbsAg +ve but -ve w.r.to HbeAg ,DNA viral load , prothrombine time and reticulocyte etc.i need adivse in this regard [/INST] Hello, You must get a liver biopsy done to look for any fibrotic changes, since your ultrasound of liver suggests mild coarse echo structure. Remember 40% of ASYMPTOMATIC HEP B +ve patients have hepatic fibrosis. Get your ALT levels also done. If your ALT level is more than 60 or if liver fibrosis is present, you must get your treatment started by getting interferons and immunomodulators. Consult a gastroenterologist regarding your treatment. Thanks </s>