<s>[INST] I ve been trying to concieve and have been prescribed a 7 day course of ampicolix for an infected graze on my foot whilst on vacation. I m mid cycle and 3 days into the course of antibiotics (the cut is wellimproved and swelling on foot has resolved) is this medicine considered safe at the stage of fertilisation should conception occur. I note that there are unproven concerns around cardiovascular effects to the fetus with use of cloxacillin in 1st trimester [/INST] Hi, Okay, the first issue is that an untreated infection is far riskier than an antibiotic. Then there are some antibiotics we know are bad and ones which are far less likely to be bad. The difference is how much they interact with our stuff rather than the germs stuff. Tetracycline not only somewhat has the same effect on us (but less) than with the germ BUT it also binds to bone/teeth. It's bad. Quinolones have very little interaction with the particular thing that the germ has BUT it is toxic to tendons probably a bit bad. Penicillin / Amoxicillin etc. hit starch coverings around most bacteria that we don't have. They are generally pretty safe. Hope I have answered your query. Let me know if I can assist you further.  </s>