<s>[INST] I have pain in my testicles with redness, and a feeling of tightness, and occasionally burning and tenderness in the tip of the penis. This happened once before about six months ago but went away on its own. This may be unrelated, but I also experience tingling and slightly chapped lips both times this occured. I have been to the clinic twice for urine tests to treat a bladder infection and also std tests, came back negative so I don`t know what to do next. [/INST] Hello need proper clinical examination and routine investigations. Investigations include routine hologram, random blood sugar, ultrasound and color Doppler of scrotum, urine RE/ME. Your symptoms may be due to many causes like epididymo-orchitis, UTI etc. Ultrasound of scrotum is important due to redness and tightness. It can assess many conditions in testis. Proper treatment depend upon findings. You may need to take antibiotics. Get well soon. Take Care Chat Doctor.  </s>