<s>[INST] Dr, My brother is diabetic & hypertensive, His creatine level is 7 now .Can we do anything for this. In his kideny scan everything is normal except a calculus 3mm showing .Waiting for your advice.His medications r   minipressXL,amaryl for pressure,statixF for cholestrol.   Nebiguard, antioxidants, shelcal ,  insulin for diabetic. [/INST] HelloThanks for query. Your brother who is known to have diabetes and hypertension is detected to have raised creatinine 7. Raised creatinine that he has is due to what is called as Diabetic Nephropathy and needs to be investigated further. Please consult qualified Nephrologist for clinical examination and get following basic tests done to confirm the diagnosis.1) Urine routine and culture.2) Ultrasound scanning of abdomen and pelvis3) Renal function tests 4) Excretion of protein in 24 urine sample 5) Renal Biopsy (If required) to confirm the grade of Kidney disease. Further treatment will depend upon result of these tests and final diagnosis. Chat Doctor.  </s>