<s>[INST] Hello, i am 29 weeks pregnant and have been diagnosed with a kidney stone in my left kidney that is too big to pass. I am prescribed 2mg of hydromorphone every 6 hours. I am now experiencing a really bad pain in my lower left back that is radiating into my left leg.  The pain medication is not helping. What could this be? [/INST] Hi, The pain may be due to kidney stone and since 2 mg of HY Chat Doctor.  If the calculus does not pass, it may initiate premature labor, produce intractable pain, cause urosepsis in the setting of urinary tract infection, or interfere with the progression of normal labor. Since the size is too big to pass the best management will be surgical.  There are many options in the surgical management (stent placement, ureteroscopy with stone manipulation, percutaneous nephrology) and hence discuss with your doctor about the same. They will be the right person to decide further management. Regards </s>