<s>[INST] My husband is on a multiple myeloma trial of lenalidomide/dexamethasone/resprim forte treatment.  He has developed a severe asthmatic bronchial condition whereby he coughs extremely during the nighttime when he is lying on his side in a sleeping position.  He cannot remove the  "bit of phlegm" that seems to be stuck there causing his discomfort. He is 74 Y.O. and this has been going on for 3 months now.  He is on antibiotics and has had 4 cycles of these.  It is distressing him as he is having body pain from the amount of severe coughing he is doing to try and cough up the phlegm. [/INST] HelloYour husband is having multiple myeloma and also taking treatment for this including dexamethasone which is also a cough reliever. In spite of this your husband is not getting relief. In my opinion this is not an asthmatic cough, but as I have noted in my so many patients s in such condition that something inhales into trachea or in airways, this produces severe bouts of cough. These inhaled particles or fluid produces wheezing or whistling type of sounds and this simulates as an asthmatic sound. But if asthma is there you may try montelukast+ albuterol tablet once or twice in day according to severity of disease or symptoms. In such cases I prescribe codeine + cholarpheniramine male at syrup 2-4 T S F twice in day. But this is a habit-forming Chat Doctor.  Steam inhalation also provide some relief with hot coffee. So consult your physician and get his opinion. Good luck. </s>