<s>[INST] My husband is recovering from C-Diff as a result of too many antibiotics due to complications from leg surgeries. He now had swollen ankles. Is this related to the C-Diff? He has taken Vancomycan and Dificid for the C-Diff plus multiple probiotics. [/INST] Hello, I understand your concern. I am Chat Doctor, infectious diseases specialist, answering your query. In my opinion ankle swelling had some different origin. C. difficile has nothing to do with ankle swelling. It is limited to the intestine only. It has never spread to ankle. Even its toxins won't spread to the ankle. I will be happy to answer your further concern, you can ask me on bit.ly/ Chat Doctor.  Thank you. ChatDoctorInfectious diseases specialist. </s>