<s>[INST] My brother has Chronic Lymphosetic leukemia...his platelets are very low...anemic, losing weight...noise bleeds....now he has developed a rash on his ankles and top of feet...with open sores...they send him for a MRI and Cat scan...could this mean his cancer has spread to another area of his body? [/INST] The picture that you have portrayed shows that the cancer has involved the bone marrow where all the blood cells including platelets are produced. Hence, the low platelet counts. Also, since the platelets are necessary for blood clotting, that is the reason for bleeding from all these sites. The reason for doing an MRI/CAT scan is dual. One to know whether the disease has spread to the brain (its is possible) and two to rule out any bleeding within the brain </s>