<s>[INST] My mother is 75 years has been in the psychiatric ward since 5/26/13 for psychosis. As per doctor early stages of dementia.  She is hallucinating, delusional agitated and aggressive.  She was on haldol for 2 weeks now on seroquel. Eating very little, sleeping few hours. The first few days on seroquel she started eating sleeping better, mood improve, then slowly again she started getting agitated, little sleep,little eating.  Yesterday she lost it started  screaming recking her room, fighting and cursing.  She had to be sedated.  Is it possible she will stay psychotic? [/INST] Hi. Haloperidol is a 1st generation antipsychotic Chat Doctor.  Psychosis includes hallucinations, delusions as well as gross psychomotor agitation (might manifest as aggression). Normally poor self-care (eating very less) and sleep disturbances accompany psychosis. Seroquel is quetiapine, a newer antipsychotic with much better side effect profile compared to haloperidol, though certain metabolic side effects like disturbance of blood sugar levels etc. are more. Now if your mother has developed psychosis at the age of 75 years, it is most likely a manifestation of some underlying organic pathology. At this age, she needs to be investigated thoroughly on these lines by neuroimaging, blood biochemistry etc., and then managed according to the findings. The symptoms are likely to improve if the underlying issues are ad </s>