<s>[INST] I have Vitiligo and was wondering if there is any connection to it with joint pain, and liver problems. I did have several bouts with Hep B growing up, and presently am having ongoing pain in my liver. I m getting tests done, but I was just checking things out on these issues [/INST] Hello, Vitiligo is an autoimmune disease. It can be commonly associated with autoimmune thyroid disorder and Type 1 diabetes.  Certain liver disease can be autoimmune as well as autoimmune hepatitis; rheumatoid arthritis is an autoimmune disorder which can be associated with vitiligo. Some more details about your clinical condition would be needed. What medications have you been taking for Hepatitis B? Interferon therapy in chronic hepatitis B too can cause Vitiligo. As you must be knowing Hepatitis B can cause deranged liver functions. Also, information about the blood tests done (complete blood count, liver function test, thyroid profile), the ultrasonography and the complete autoimmune profile if done (like ANA, rheumatoid factor).  The current status of your Hepatitis B is needed (like the last Viral DNA levels) and what medications you have been taking for it. You can contact an internal medicine specialist pr gastroenterologist for the same. Hope I have answered your query. Let me know if I can assist you further. Take care  </s>