<s>[INST] Recently, I had a rocephin shot and was on bactrim for a week for a UTI . After I finished the bactrim I had a rash on my waist and back. Dr said probably a reaction to bactrim and put on a prednisone dosepak for a week. All that went away, but the inside of my bottom lip feels dry and very leathery. Could this, too, be some kind of reaction? Wednesday will be 2 weeks since I finished the medicine. [/INST] Hi, After reading your history it appears that you might have developed allergic dermatitis over the area. I advise you to not pinch or pop the area. You can apply an antibiotic cream such as gentamicin cream. Antibiotic tablets are must such as ciprofloxacin and metronidazole under medical advice. If itching is present then can take Ben Chat Doctor.  You can take painkiller like Ibuprofen or paracetamol or diclofenac according to the pain severity. Consult your operating surgeon to look for the exact situation and treatment of the problem. </s>