<s>[INST] I am having blood sugar spikes all of a sudden. I have been on Glamepiride 1/2 to 1 tablet 1 x a day. I have been on 1/2 pill but have gone from 135 to 174 all of a sudden. Time to go to 1 pill. The danger is bp being too low with 1 pill a day. I was borderline Type 2 diabeties, and have gone to definite recently. [/INST] Hello and welcome to ask a doctor service. I reviewed your query and here is my answer. There are multiple factors involved in increased blood sugar and getting diabetes. The more notorious are obesity, over eating, stress and depression and positive family history. You need to work on your lifestyle, lose weight if you are obese. Don't over eat. And do daily exercise for about 15-30 mints at least. And have a healthy diet. How many mg of glimeperide you take? Look at your diet and if it is still increasing, then your dose should be increased or another Chat Doctor.  Hope I answered your question.  Feel free to ask if you need further assistance.  Thanks. </s>