<s>[INST] Hi Doctor, I am a patient of Psoriasis from Last 10 years , It has began from head and then spots on the body...the same was cured 5 years back but now  the spots had started again appearing on my body, nails  and hair. Is this disease is permanently curable.... [/INST] Hello, I very well understand your concern for psoriasis. Psoriasis is quite long-running problem and with proper treatment remains in control. It is not at all life endangering condition and is due to simple fast proliferation of skin within 4-5 days. For the treatment and control of this condition Methotrexate is the main of the treatment. It should be taken only under dermatological supervision with proper blood tests as it has its own blood and liver related side effects. I suggest you to take dermatological advice and take proper treatment accordingly. All the best. </s>