<s>[INST] Can you can take Bactrim and Doxycycline at the same time for Chronic Prostatitis? I have both and have been taking Bactrim for 2 + 2 weeks with a 7 day break in-between . Still Have burning sensation in the peritoneum after the total 4 weeks of Bactrim [/INST] Hello dear, Thank you for your contact to Chat Doctor. I read and understand your concern. I am Chat Doctor answering your concern. Yes one can take both the Chat Doctor.  There is no harm in it. But it seems that resistant organism is growing in the infection. In such a condition I won't advice you to take many antibiotics, instead I advise you to do culture and sensitivity from the infected site. Taking the  </s>