<s>[INST] I have had bad knee pain for over four years with no relief. I have done two rounds of physical therapy, custom orthotocs, and two rounds of orthovisc injections. Nothing has worked. I can no longer run, or ride mu bike. My knees hurt when I sit, stand, walk, basically everything. I was told I had patellofemoral syndrome, and then they said patellar tendonitis because nothing worked. But my MRI and xrays didn t show anything they deemed helpful. Any help I get would be appreciated [/INST] Hi, I value your concern regarding the symptoms. I have gone through your symptoms, and in my opinion I would first like to know your age, are these symptoms in both knees, and are other joints involved. Also tell what is your status when you get up in the morning, is there body stiffness of you feel relaxed.  In such patients we normally prescribe an X-Ray to see any evidence of arthritis, and based on this we further investigate. In your case It's highly unlikely that your MRI is normal. Hope this answers your question. If you have additional questions or follow-up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health. Special note-Any medication prescribed needs to be taken after consultation with your personal doctor only. </s>