<s>[INST] Lexapro, lamatical, wellbutrion, I have been taking medication for over 20 years. Added every so often, Xanax. Unable to speak clearly, can not think clearly. I have been diagnosed bipolar, depression, manic, sleep, ambient as needed. I would like someone evaluate my brain. SO this effect does not became worst. [/INST] Hello, Thanks for choosing Chat Doctor for posting your query. I have gone through your question in detail and I can understand what you are going through. Well you are already on plenty of Chat Doctor.  The only reason I see, why you are not improving is:1) Learn is an SSRI and will cause switch in a case of depression. This is undesirable in a case of bipolar mood disorder.2) There is only one mood stabilizer. That can be augmented with valproate. Valproate is one of the first line mood stabilizer and would be effective in your case. 3) Also there is an option of cognitive behavioral therapy (CBT). This therapy is taken by either a psychologist or a psychiatrist in which the therapist identifies impaired cognitions (Thoughts) and try to correct them. They are 15-20 min weekly session and there should be around 8-10 sessions to help you with your illness. MRI scan and other investigations of your brain will not reveal much if it's a psychiatric illness. They will definitely not be very useful. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. In future if you wish to contact me directly, you can use the below-mentioned link:bit.ly/ </s>