<s>[INST] sir, my father is suffering by gall bladder. and he having lots of pain in right stomach. in ultrasound report he found that he having a gall stone 6mm major mutiple. is there any thearphy to removing gallstone without surgery. give me true guide line related for it [/INST] HelloMultiple gall bladder calculi(largest: 6 mm)is not expected to get removed without therapy. I suggest for definitive treatment of gall bladder stones. Definitive treatment is surgical removal of gall bladder(cholecystectomy). Gall bladder calculus are prone to infection and obstruction, so it is wise to get rid of it. Gall bladder calculus usually doesn't respond to medical management. In some patient, trail of gall stone dissolving medicines like ursodeoxycholic acid tablet may be helpful in dissolving calculus. Get well soon. Take Care Chat Doctor.  </s>