<s>[INST] my father-in-law is 78.he has been diagnosed with coarse cortical echotexture of both kidneys. a simple cyst (21.5 mm x 20.7mm) seen in right kidney. LIVER-diffusely increased echotexture.right lobe measures 120.4mm. is his end very close.we are all shattered in the family. [/INST] Hello USG findings may indicate renal parenchymal disease. This is indicated by coarse cortical echo texture of kidneys. Your father-in-law need clinical examination and further investigations. Investigations include routine hologram, random blood sugar, renal function test(include serum urea, creatinine), creatinine clearance, GFR,serum sodium, potassium,calcium, phosphorus,chloride, bicarbonate etc. It is important to assess severity of illness. Treatment depend upon findings. Simple cyst in kidney is an age related finding, and it is a benign finding. Diffusely increased echo texture of liver indicates fatty changes in liver. Fatty liver is a reversible condition, and it can be reversed by diet and lifestyle changes. Take Care Chat Doctor.  </s>