<s>[INST] my semen analysis showed pus cells and whenever I ejaculate there is inflamation over my penis. Sir, what could be the reason. My age is forty five years, weigh is eighty kgs. and I was treated by antibiotics a couple of times and also took homeopathy treatments but still it the problems remains. [/INST] HelloThanks for query. Presence of pus cells in semen is strongly suggestive of infection either in Seminal Vesicle or in the majority of cases in Prostate. Taking antibiotics either Doxycycline or combination of Sulphamethoxazole and Trimethoprim twice daily helps to control the infection. However since you had taken antibiotics for many years I would suggest you to do Semen culture to detect organisms causing this infection so that you can take appropriate antibiotic as per culture report to help in eradicating infection. Chat Doctor.  </s>