<s>[INST] I AM A CKD PATIENT NOW ON CAPD. NEED TRANSPLANT. MY KIDNEYS NOT BEEN DONE ANY BIOPSY BUT MY DR. IN KUWAIT IS TELLING KIDNEY FAILED DUE TO ANTI GBM ANTIBODY.I HAVE SKIN DISEASE FOR 35 YRS AND I THINK THERE IS RELATION BETWEEN THIS SKIN DISEASE AND KIDNEY DISEASE.IF I GO FOR TRANSPLANT, DOES THIS PROBLEM AFFECT MY NEW TRANSPLANTED KIDNEY? [/INST] Hi, A lot of research is going on the topic of anti-glomerular basement membrane (anti GBM) antibody disease recurrence after transplantation. Anti-glomerular basement membrane (GBM) antibody disease may progress to end-stage renal failure, requiring either dialysis or renal transplantation. There are only six reported cases of symptomatic recurrent anti-GBM disease in the literature. The incidence of recurrent linear Immunoglobulin G (Egg) staining in the transplant may be as high as 50 percent. However, most patients remain asymptomatic. You may discuss this point with your doctor. </s>