<s>[INST] The patient is my father-in-law. He has just been diagnosed with prostate CA with Gleason score (4+5 = 9/10) and with mets to D2 and D3. He is suffering from constipation and severe bone pain at the aforementioned level. He weighs 43 pounds and approximate height is 5 feet 3 inches. He has almost zero appetite. What is his prognosis? He also complains of constipation and left arm numbness.  Are these symptoms associated with CA? [/INST] Hi, dairy have gone through your question. I can understand your concern. He has Prostate cancer with Gleason Score (4+5 = 9/10). Prognosis is very poor. Gleason score more than 7 is indicator of poor prognosis. He also has bone metastasis. So prognosis is very poor. Life expectancy is not good despite all treatment. His other symptoms are due to his cancer. So only symptomatic treatment is given at this stage. Consult your doctor and plan accordingly. Hope I have answered your question, if you have any doubts then contact me at bit.ly/ Chat Doctor. Thanks for using Chat Doctor. Wish you a very good health. </s>