<s>[INST] hi,i am xxxx..age 26 years..i have been suffering from psoriasis for 5 yeas...today I noticed that it spraed in my back portion..doctor told me that it is treatable but not curable..it feared me a lot...if it spread all over my body...can you please suggest me if that is not curable..how can I get rid of this??my email address is  YYYY@YYYY ... [/INST] Hi, I can understand your concern for psoriasis which is spreading to entire body. Psoriasis is a long-running disease and needs proper best treatment. It is due to fast renewal process of the skin. Methotrexate is the mainstay of the therapy but has its own blood and liver related side effects. Always take it under dermatological advise otherwise can cause serious side effects. You should start it after dermatological supervision and complete blood counts and liver function tests. Topical steroids such as clobetasol can be used in combination with moisturizing cream. Take care. </s>