<s>[INST] Sir good morning, My father age 50 year is suffering from hepatitis B from last 1 years. a Gastroenterologist Dr. Advise medicine Hepdoz 300 OD & he say that the liver is damaged ( Sirosis) i fallow the treatment & investigations 1 years but we are not satisfied with result, now i m given liv 52 hb (BD) & syp hepavin (BD) from 1 month PLZ advise me dose & duration of this medicine for HBSAG negative Tech. Rajesh Tiwari Avadh Hospital, Gonda U.P, India [/INST] Hello! Thanks for putting your query in Chat Doctor. I am a Gastroenterologist (DM). Presently with the available treatment for Hepatitis B like Hep doze which have been prescribed to your father is one of the best medicine. Present treatment cannot make Bag negative, only there is around 5% chance of complete disappearance of virus from body. He has developed cirrhosis which is irreversible. You may add tablet Adílio 300 mg twice a day. Hope he has not developed ascites or altered behavior (Hepatic encephalopathy) till now. So he has good prognosis overall. No other treatment is available at present. You have to understand that. I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon. </s>