<s>[INST] hello my doctor prescribed me doxcycline for a sinus infection and after day one i broke out into hives on my hands and my eye was inflamed and my penis feels itchy. I have stopped the antibiotic now and am on antihistamines and steroids for a few days. comments? [/INST] HiT hank you for asking ChatDoctorI have gone through your query. Your problem is most likely urticaria due to an allergic reaction to doxycycline. You should remember this Chat Doctor.  For such conditions I treat my patients with antihistamines and corticosteroids. If severe itching is there I give them one dose as injection of those two. I as advise them to apply calamine lotion locally to get soothing effect. Hope this may help you. Let me know if you have any further query. </s>