<s>[INST] My granddaughter is 4 yr old & is on medication fo primary complex ( rifampicin, isonizid & pza) for less than a wk now. Are ther effects that we must be worry about? I know t liver damage is one effect, can this giv other problems like recurrent fever? Just this morning we notice a slight blood ( very small amount dry blood on one of her teeth-upper). Must we be alarmed? Thank you. God bless. [/INST] Welcome at Chat Doctor I have gone through your query and being your physician I completely understand your health concerns These medicines have got the variety of side effects like liver damage, derangement in renal functions, increased uric acid levels.  There is need to get the frequent liver function tests analysis so that dose of the Chat Doctor.  In addition to it, it also causes pink discoloration of body secretions like in tears, urine and saliva. They do not cause recurrent fever.  Maintain proper follow up with your physician.  Meanwhile, stay calm Get well soon Hope your query is adequately ad </s>