<s>[INST] hello doctor, I am physiotherapist. my query is about consanguineous marriages, My parents are arranging marriage to my cousine only, i have a doubt about children health.Please guide whether their will be any physicall or mentall disabilities in the children. [/INST] Hi...scientifically seeing consanguineous marriages are not advisable as the kids may be prone for some inherited disorders which might be running sub-clinically in the family line. Another issue is that it can lead to pregnancy complications and birth weight issues. But at the same time it doesn't mean that all consanguineous marriages will lead to defective babies. It is not so. The best way for you will be that - Consult a genetics specialist (both of you) and get evaluated and then take a decision of the marriage. Regards -  </s>