<s>[INST] my son, 25 years old has big big outbursts of anger,throwing things, blaming every one on his bad things in life, very poor cleaniness, very low enery, no job, now lives with grandparents. he makes his sister feel sooo bad, he blames her for most things. early on there were very close. she has a job, and doing well. I had his birdthday last nite with cake and pizza, thought had a good time but he thought it wasnt enough. He is middle child older brother 30 and sister 21. I have been divorced from their father for about 19 years. he was drug and achol aburser. [/INST] I appreciate your concern on Chat Doctor. The symptoms you mentioned such as low energy, poor cleanliness, anger, no job and your divorce point towards that your son may be suffering from depression in which a person loses interest in life, develops mood changes and decreased energy levels. Treatment is available and up to 70% people recover. Self-help treatment includes self-help cognitive behavioral therapy and professional help includes antidepressants and psychotherapy. I hope you find this helpful. </s>