<s>[INST] hello doctor my father is aged 70. He suffers from peripheral neuropathy for the past 5 years. He has mild diabetes. He has taken many medications but to not much effect. I have heard that 2500 micrograms of methylcobalamin injected with saline intrathecally gives good results. Also a cream called capsaicin also helps. Kindly advise the best medicine. Regards Kishore Bhargav [/INST] Hi, First, your father should take vitamin B complex, twice a day after meals and one ampule vitamin B 12 every week, besides controlling the blood sugar. Moreover, the healthy diet is essential, he should avoid fat-rich diet and too much salt in diet. The regulation of the blood pressure is mandatory besides, checking kidney functions and his eyes every six months. He could take methylcobalamin 1000 micrograms oral once per day after meals. The injection dose is too high for him. Capsaicin cream is good for him when he suffers from pain. Hope I have answered your query. Let me know if I can assist you further.  </s>