<s>[INST] I am female age 53  and for a few years suffered with fatigue, getting worse. I work full time and find it difficult to concentrate. I regularly go to bed about 6pm and get up at 7am to 8am still feeling exhausted. I have blood pressure tablets and beta blockers, I now take vit D supplements advised by my Doctor who a;lso said I was depressed!!!!I started to take 2 types of anti depressants but they really made me feel too sick and nauseous. I have stopped taking.I am not feeling low or unhappy but just so tired all the time. I have just returned fro  2 weeks holiday where I was fine, but now struggling to get out of bed, please help. [/INST] Hi, Thanks for using Chat Doctor. I have gone through your available history. Tiredness and lack of concentration might be due to - Thyroid dysfunction- Vitamin B12 or vitamin D deficiency-Depression- Menopausal syn Chat Doctor. You should rule out thyroid dysfunction and vitamin Deficiency by doing blood investigations. You may get prescription by your doctor. Treatment would be directed as per cause. Sometimes excessive sleep may also make you fatigue. In that case you may need to reduce sleeping hours. Thanks. </s>