<s>[INST] Hi, I have been diagnosed with lupus and am dealing with it for 7 years now. I am on cellcept and plaquinil and enalapryl for 2 years now. I have been haivng my periods every 2 weeks ( 2 per month ) with a lot of cramping from September 2013. I dealt with it a couple of months then in Nov my do put me on Ortho tricycline. I have been taking it for a little over a month and my periods are still not regularized. I started having very bad acne from summer. In Dec, my doc put me on antibiotics ( for one month) on minocyclin. I am worried about my periods--what do I do? [/INST] Hi and thanks for the query. ChatDoctor and very pleased to be assisting you with your health questions today. I am so sorry to hear that you are suffering from all these difficulties. There are many other medicines available for your irregular periods like other combination of above Chat Doctor.  You should discuss with your doctor you have any further queries, please donor hesitate to call me again Hope this helps and provides answers to your question. I wish you good health. </s>