<s>[INST] My wife aged 33 ..had high BP during May 2012 and as per family doctor s advise she took Envas2.5mg (one time in the morning) and we went to Apollo last week and doctors suggested to take Stamlo2.5. Her both kidney size are normal...as per report the thickness is 0.47 & 0.48 for this reason we are not able proceed with renal biopsy . Her creatinine level 3.1 [/INST] Hi, Thanks for posting your query. Is she undergone ultrasound imaging of kidneys? What are the reports? What was the size of kidney in ultrasound imaging? Is cortico-medullary differentiation maintained or not? Size Raised creatinine may be due to acute renal failure (ARF) or chronic kidney disease (CKD). By ultrasound imaging and urinalysis, CKD and ARF can be differentiated. You should consult with physician/ nephrologist and should follow diet plans. You should also take prescribed medicines as CKD is associated with multiple complications. Medicines in CKD are advised to live smooth life.CKD are generally associated with rise in hypertension (as in your wife case). Is there any rise in blood sugar? Diabetes and hypertension are the 2 most common disease worldwide for renal failure. Keep watch on serum creatinine level. Regarding medication for blood pressure, you can go stable 2.5 while Elvas is generally not given if creatinine is > 2.5 (as in your wife case). You should go for renal biopsy if the cause of renal failure is not clear. Take Care, </s>