<s>[INST] lo estrinwhat are the pros and cons of the birth control loestrin? i am wanting to provent pregnancy, clear my acne, and regulate my period. i was on a birth control called apree for two years it did a great job clearing my acne but i made the mistake of skipping two months and when i tried to go back on it i started getting yeast infections every month. ive been off of birth control for one year and since then i have gained a lot of weight, i went from 160-205, my acne came back, and my periods are very irregular. wich birth control would be best for me? [/INST] Hello welcome to Ask A Doctor service. I have reviewed your query and here is my advice. Ethinyl estradiol and desogestrel containing pill can be taken as contraceptive pill. But every combined pill have some form of side effect like weight gain, spotting, nausea etc. Barrier method is safe and without side effects. If you want to continue contraceptive pill than exercise and lifestyle changes should be done to reduce weight. I suggest you to consult gynecologist for examination. Hope I have answered your question. Let me know if I can assist you further. </s>