<s>[INST] My wife s ESR level is 63. She is OK. No fever, No cough. She has undergone most of the medical checkups ie. X-ray of Chest, Sonography, Upper Endoscopy and Mammography. But all the reports are OK. Please advise how to reduce the ESR to a minimum level. HAARI [/INST] Hi, dear. I have gone through your question. I can understand your concern. You have high ESR.  There are many causes of high ESR like tuberculosis, anemia, infection, autoimmune diseases, malignancies you should go for further investigation like ANA profile test.  Consult your doctor and take treatment accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using Chat Doctor. Wish you a very good health. </s>