<s>[INST] A few years ago, we were on a beach in Spain.  My wife had her toes buried in the sand.  She immediately complained of burning.  Her toes became red, swollen and blistery and quite painful.  This has been several years now and from time to time the symptoms reoccur.  Any idea what this could be? [/INST] Hi, I have gone through the medical history of your wife and understood your concerns. You are reporting that your wife had her toes buried in the sand, and complaining of burning, swollen and blistery. Mos probably, her toes got not only burned but also infected. Perhaps at that time she was not treated appropriately with antibiotics. You are saying that the symptoms are re-occurring. If her toes or legs get inflamed (red, swollen and blistered) then, these are signs of possible infection. Antibiotics are advised. Erysipelas should be ruled out by her physician as it needs special attention and treatment. Hope it was of help! Chat Doctor.  </s>