<s>[INST] My liver profile (3rd one taken), my ast/sgt went from 60 u/l to 100 u/l , my alt/sgpt went from 100 u/l to 197 u/l, my alkaline phosphate 536 to 1015. What exactly does ast, alt and alkaline levels this high indicate? Im negative for hepatitis dr ran test for all of them. Levels are rising. [/INST] HelloSign SGPT may indicate liver injury. It may be due to many reasons like hepatitis, alcohol intake, altered lipid profile, medicines,autoimmune causes etc. Findings also suggest raised alkaline phosphatase. It is important to know bilirubin level. Raised alkaline phosphate may be due to hepatobiliary obstruction. CT scan of abdomen can be done if needed. You may need few investigations like routine hologram, random blood sugar, ultrasound of abdomen. I suggest tablet ursodeoxycholic acid 300 mg twice daily for three months to my patients. It helps in regeneration of liver cells. You may need to take few more medicines after investigations. Increased GOT is non-specific, and it increases in many conditions. Get well soon. Take Care Chat Doctor.  </s>