<s>[INST] My wife 33 years old premenopausal women 171 cm ht,64 kgs weight had left radical mastectomy & left axillary dissection  20 days before ,confirmed on biopsy grade-2 ductal carcinoma & 12/24 lymph nodes with metastatic carcinoma?.week before undergone full body PET CT scan ,impression is no critical disease any where in the body & no metastatis.But our oncologist says 8 cycles of chemotherapy to be done ,radiation therapy to kill microscopic cells which cannot be detected by PET CT.We are worried of chemotherapy but we do not have option.Suggest please [/INST] Hi, dairy have gone through your question. I can understand your concern.  She has ductal carcinoma of breast.  Stage 2 with no metastasis.  She has already gone through surgery.  Noe she should take chemotherapy.  She should also check for ER, PR and her 2 new. If this receptor is positive then receptor specific antagonist treatment is very useful in breast cancer. Consult your doctor and take treatment accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using Chat Doctor. Wish you a very good health. </s>