<s>[INST] sir i am lalitha . 3or 4weeks no mood for working in houes  iam consulting in medical collage tcr in psychatrist department and  Dr said iam a depresed person and gave him medicine citapam and ramitax .2week i contine the medicine but no effect still . no sleep in night and no mood for working.   please help me  sir [/INST] Hello, Increase the dose of citalopram to 15-20 mg and if still there is no effect - please change to sertraline. For sleeping: try clonazepam 1 mg or collided 12.5 mg. Once sleep is restored nicely, you will start feeling better from the very next day. You should also get TSH level and It. B12 levels as they can be deranged. You may talk to your treating team regarding the above points. Donot worry, you will definitely get better. Just give meds sometime and increase the dosage. Good luck. </s>