<s>[INST] my spouse had stage 3 thymoma resection in july with radiation therapy and was feeling little better. for three weeks now he has been experiencing the constant chest pain, shortness of breathe, fatigue just like when the tumor was discovered. His radiation oncologist doesn t seem concerned however it went from stage 2 to stage 3 mastatis in four months. How concerned should we be of this reoccurring or moving to another location while we are waiting to get his routine ct scan? I have been told that it can move to the brain and he has been experiencing more than normal memory loss for a 49 yr old men. [/INST] Hi, Thanks for writing in. It is unfortunate to know about the disease progress and discomfort in your spouse. Thomas responds the best to radiation treatment, and he is getting treated regularly. It is important to know the field of radiation and any chemotherapy that was given to him during last few months. There are certain medications that are toxic to the lungs and might cause lung fibrosis. A CT scan is a must to assess any lung changes due to chemotherapy and radiation. Any spread of disease must also be evaluated in detail. It will help if he also gets a brain scan to know if there is any condition that is causing loss of memory. </s>