<s>[INST] I am facing constant resistance from my family members,unfortunately i dont have any friends to share my problems.My parents have disowned me,and even have not been able to get into any  marital relationship  yet.All this is making me depressed,how to cope with it? [/INST] Hi, I am sorry to read about the problems that you are facing in your life. It is certain to impact anyone's life and I can understand what you must be going through. I would recommend that you consult a psychiatrist for initiating treatment for depression. Treatment with anti-depressant medications like venlafaxine or sertraline would be beneficial in your state. In addition, you can also opt of psychotherapy sessions in form of cognitive behavior therapy which will help you learn relaxation and help you overcome negative thoughts in your mind. I do hope that I was able to answer your query. Best wishes. </s>