<s>[INST] Few years ago, I have been diagnosed CLL plus pure red cell aplasia so for I have taken 45 units of blood transfusions. Could you tell me how aplasia can be treated. Is that Bone marrow Biopsy can be avoided as I had back injury few years back and some time nerve get pinched. so trying to avoid Bone marrow biopsy. A. B [/INST] Hi, dairy have gone through your question. I can understand your concern. You have to confirm the diagnosis of pure red cell aphasia by bone marrow examination. Treatment of choice is bone marrow transplantation. Till that you can take blood transfusion to maintain your hemoglobin level. Consult your doctor and take treatment accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using Chat Doctor. Wish you a very good health. </s>