<s>[INST] I am newley prescribed Coreg BID 3.125mg. My doctor mentioned the effects of lipids it has where Toprol XL does not have those effects. I was on Toprol xl 50mg daily. What is he talking about? I am a nurse and want to understand his reasoning by switching my medications. I take this medicine for a racing regular heart rate. and borderline hypertension along with HCTZ 25mg daily. [/INST] Hello! Welcome on Chat Doctor! I understand your concern and would like to explain that both Tool XL and Core have an adverse impact on lipid profile (they tend to increase triglyceride and cholesterol fractions mildly). Nevertheless, this is not a clinically relevant effect, and you should not worry about. The real advantage of Core when compared with Tool is regarding its more potent beneficial effects regarding hypertension treatment, as it possesses also vasodilator properties. Hope to have clarified your uncertainties. Wishing you a good health! Kind regards, </s>