<s>[INST] Hi, I have a PCOS issue and i was asked to use Letrofil for the first month after my menstrual date, and then clomifene for the next two months. I checked in one of the website that Letrofil is not allowed to be used in young Pre-menopausal women. Will it affect me if i start using Letrofil? Please clarify my doubt.. [/INST] Hi, Aromatize inhibitors can't stop the ovaries from making estrogen, so aromatize inhibitors are mainly used to treat postmenopausal women. If you're a premenopausal woman willing to take medicine to suppress your ovaries, you may be able to take Aroma sin instead of tamoxifen for your hormonal therapy treatment. Hope I have answered your query. Let me know if I can assist you further. Take care.  </s>