<s>[INST] i m 52 years male. Is recuperating from heart attack. am taking autrin once daily as per prescription. It is giving me constipation and fissures with lot of pain. I have to take Iron as my he=aemoglobin has dipped very low after angeoplasty. please advise how to manage the side effects and take the best out of autrin. Thanks [/INST] Hello, I will suggest you to continue autumn as it has nothing to do with your constipation. You need to monitor your blood loss source as if it is because of this fissure related bleeding? You need to take fecal softeners as there is a compulsion for blood thinners post angioplasty (your fissure bleeds more than compared to others). If problem persists, it is recommended to do anal dilatation to relive this constipation and anal fissure. Hope I have answered your query. Let me know if I can assist you further.  </s>