<s>[INST] I am 44 year old woman with chronic renal failure and take Alprim daily for persistant UTIs, but I have watery stools the longer I take medication,  only took Alprim till a few weeks ago for short doses of 7 but the increase does not seem to be working is there anything other than this to take? thank you    Sharon [/INST] Hello, Alp rim is an antibiotic.  Taking it for long time along with killing the microorganisms in the urinary tract, they also destroy good microbial flora in the intestine, causing loose stools . This is a protective coverage which prevents any bad organism to colonize in the intestine, Hence, prebiotic supplements are recommended when you take aren't idiotic for long. Yogurt is a very good natural source. Sporadic/ eco norm are commercially available sachets containing profit in. They should be taken 3 times daily for treatment and once daily for prevention. Regards Chat Doctor.  </s>