<s>[INST] Dear Doctor, I am 54 years old male.  I have high cholestrol.  I had taken Lipanthyl 300 for 2 months and the cholestrol level came down.   Now I hv stopped it for 2 months and now I am having high BP 145/90.  I also drink every night, else I do not get sleep.  Is there any reaction for Lipanthyl with alcohol ? [/INST] Hello, Thanks for writing to Chat Doctor, I am Chat Doctor. Lipanthyl and alcohol do not have any significant interactions in my opinion and normal quantities can be used at the same time. Just keep an eye at your cholesterol levels stay active, take lesser fat and if it stays in range you can discuss with your doctor about leaving the medicine. A blood pressure reading of 145/90 is quite appropriate, you do not have to change medication for that. In fact first step would be to change lifestyle. My advice for you is:First change your lifestyle. Use less salt and fat.  Stay physically active. Avoid Coffee caffeine, smoking (what ever is relevant). Lose weight if you are overweight. Monitor your blood pressure regularly if it stays consistently above 150/90 for a week instead of all the lifestyle modifications, do visit your doctor with that record to get the medication adjusted.Lifestyle modifications will get your BP below 140/90 and you won't need any new medication, you can discuss this BP with your doctor in next visit, but there is no emergency situation with this reading. I hope this answered your question, If you have more queries I am happy to answer you. Regards. </s>