<s>[INST] i had an ultrasound at 27 weeks of pregnancy. My AFP came bck normal and echogenic foci & chorionic cysts had resolved. A good ultrasound altogether. now i am 31 weeks pregnant and my friend (who is an ultrasound technician) noticed a possible duodemum atresia. Is it possible to have this after a good ultrasound at 27 weeks. She does not specialize in OB but does occasional ulrtasounds on pregnant women with issues earlier in pregnancy. should i be concerned? [/INST] Hi, If the technician suspects duodenal amnesia, better to get a second scan done by a fetal medicine specialist. She will not only confirm/rule out the amnesia, but also advise you the next steps if problems are identified. And a normal scan will definitely decrease your anxiety. Since you have also has echogenic loci and chorionic cysts which eventually resolved, but they are considered to be soft markers for Downs, these with a present finding, if at all of Duodenal amnesia usually warrants for an amniocentesis, to check for fetal chromosomes, and to rule out Downs. Hope this helps. Regards. </s>