<s>[INST] Hi. I am 24 years old. weight:65 kilo, height: 174 cm. Two years ago I found that I have hepatitis B. Two years ago my GPT(ALAT) was 21, GPT(ASAT) was 21. Now my ALAT is 40 & my ASAT is 27. My virus load is very low ( 0.050 - international units). Can you tell me what that increase in ALAT indicate for & can the virus pass to another person through saliva? [/INST] Hi thanks for contacting Chat Doctor... Here it would be ALT mostly not ALAT... Normally it is up to 42.... Here it is 40.... So not increased...... This enzyme present in hepatocytes .... When injury to hepatocytes then it will be released through sinusoidal in blood and detected as increased level.... So its high level indicate more injury to hepatocytes... This virus present in every secretion but low concentration in saliva.... If contact person have ulceration then chances of spread more if it comes in contact.... If exposed person vaccinated then chance very less. Hope your concern solved. Take care. Chat Doctor.  </s>