<s>[INST] My mother in law has brain cancer glioblastoma. She is in Ireland. We believe it is near the end. Suddenly she now is in pain. The morphine patches are only 5mg. We are so upset about her pain. She is on steroids also. She has lost vision and is bed bound. She is 84. How long? [/INST] Thanks for your question on Chat Doctor. I can understand your situation and problem. Pain due to terminal stage cancer is very difficult to manage. We have to give centrally acting painkillers and sedative Chat Doctor. Transdermal fentanyl patch is very effective, and its effect lasts for 72 hours. Low dose sedation also helped patient to reduce the suffering s from pain. Discuss end of life issues with her. </s>