<s>[INST] I there my husband has a long history with cvid, now just ran test that were off the charts high S-BILRIBIN S-ALKALINE PHOSPHATASE S-G-GLUTAMLY TRANSERASE D-DIMER What are these test for?? used to all the markers for cancer and FBC and IGA etc but dont know these, also his platlets are still high enough for him to keep his spleen , please help me understand so that I can understand better and stop unnessary worrying. Its easier to know sometimes than to be kept in the dark [/INST] Hello TheresaThank you for getting in touch with us. As I see, your husband has a past history of AVID. Common Variable Immune Deficiency is a disorder characterized by low levels of immunoglobulins (antibodies). The result of these defects is that the patient doesn't produce sufficient antibodies in response to exposure to pathogens. As a result, the patients immune system fails to protect them against common bacterial and viral infections. The net result is that the patient is susceptible to illness. It is not as deadly as severe combined immunodeficiency (SCID). Serum Bilirubin, SEPT, GOT tests are used to check the function of liver. These are not markers for cancer. As his platelet count is still high, he can fight infections on his own and the spleen is working properly. Hope this helpsRegards </s>