<s>[INST] I look a urine and blood test recently for life insurance and it came back that I had elevated GGT and ALT levels (GGT 312 and ALT 60). I NEVER drink or smoke. I am about 50 pounds overweight. I m 6 0 and 260. I don t have a family history of any type of disease. I m getting so many mixed answers on what could cause this. Everything says alcohol or pills which I take neither. Could being overweight cause it and what should I do to lower it? [/INST] HelloIncreased GGT and ALT may indicate liver injury. It may be due to many reasons like hepatitis, alcohol intake, obesity,altered lipid profile, medicines,autoimmune causes etc. It may be due to obesity in your case. You may need few investigations like routine hologram, random blood sugar, lipid profile, viral markers, ultrasound of abdomen. I suggest tablet ursodeoxycholic acid 300 mg twice daily for three months to my patients. It helps in regeneration of liver cells. You may need few more medicines after full investigations. You should try to reduce your weight. Take a lot of fibers in your diet and go for exercise regularly. Get well soon. Take Care Chat Doctor.  </s>