<s>[INST] hello doctor. i am 28 yrs old undergone for renal transplant in july 2008. I am suffering from diarrhea from few days. I was admitted for 2 days and was given ciplox 100 through IV. I am taking medications as under. Pangraf(tacrolimious)-1.75 mg-----6am & 6pm omancortil 10 mg--------9 am azoran 100mg-----------10 am nicardia retard 20mg---------- thrice a day. This is the 3rd time i have been suffering from diarrhea. my Creatinine level was 2.2 high but now it is 1.8 lowered. I need help to come out of this diarrhea. [/INST] First you need to look for the cause for diarrhea. You should do stool examination for routine microscopy and for opportunistic infections. These may give clue to possible pathogens, and we may treat by specific antimicrobial. Second for high creatinine you should do program level to look if doses are high.Also, non-infective causes of diarrhea needs to be evaluated in consultation with your doctor. Take care. </s>