<s>[INST] My husband was recently diagnosed with diabetes. He is also on medication for high blood pressure and high cholesterol.  He is an alcoholic and his most recent Alt test was 140. He has convinced himself that the alcohol does not have an effect on his liver function test. [/INST] Hello Thanks for writing to ChatDoctorYou husband has increased ALT, and it indicates liver injury. Increased ALT may be due to hepatitis, altered lipid profile, autoimmune causes, medicines etc. In your husbands case, increased ALT is related to alcohol intake. Alcohol causes devastating effect on the liver, and he should quit it immediately. He needs clinical examination and few other investigations. He needs few more investigations like random blood sugar(RBS), renal function test(RFT), complete lipid profile, Liver function test, viral markers, GGT estimation, urine RE/ME, ultrasound of abdomen. He should avoid red meat and high fat milk products. He should avoid fried and junk food. Medicines should be prescribed after complete investigations. I suggest my patients to take tablet ursodeoxycholic acid 300 mg twice daily after food for three months. This help in regeneration of liver cells. He also needs medicines for high blood pressure and high cholesterol level. Get well soon. Hope I have answered your question. Take Care Chat Doctor.  </s>