<s>[INST] Hello, Im having a sharp pain on my wisdom tooth and the doctor prescribed Pontalon 500mg painkiller to be taken every 8 hours along with some antibiotic. My question is, since the pain sometimes get worse, is it ok to take the painkiller every 4 hours though? Would that caused permanent damage to my kidney? The doctor asked to come back once the antibiotic is finished so that he could remove the wisdom tooth. [/INST] Thank you for your query in Chat Doctor forum. Pentagon (Metonymic acid) is an analgesic of a specific group called NSAID. There are several analgesics available in this group which are having same or more potency but less side effects than Metonymic acid(MA). The use of MA has been reduced worldwide because of its comparatively more side effects than other NSAIDs. The actual dosage of MA is 500 mg 1st dose or maximum 2nd dose after 6 hours then 250 mg every 6 hourly not more than 7 days. Always take MA immediately after a meal,in full stomach and with a full glass of water. You can not take the medicine every 4 hourly. You could have a severe stomach irritation and have permanent gastritis/ulceration with over dosage MA. Other several side effects may also arise. Practically you are taking higher doses than pharmacologically prescribed. There is no risk of kidney damage with 7 days dosage, But long term intake may damage your kidney. For any dental pain Paracetamol 1gm 4 hourly is enough and safest analgesic to get comfort from pain. Thank you. </s>