<s>[INST] I HAVE BEEN DIAGNOSED WITH MULTIPLE NEURO FIBROMA AND MOTOR NEURON DESEASE. FOR THE PAST TWO MONTHS I GET A SEVERE PAIN WHICH ORIGNATES FROM THE LEFT BACK SIDE OF THE WAIST AND TRAVELS DOWN TO THE BASE OF THE LEFT FOOT. IT GETS AGGRAVATED IN EARLY MORNING GET UP TIME.I ALSO SEEM TO BE LOOSING GRIP OF BOTH THE HANDS.I KEEP ON DROPPING THINGS ALL THE TIME. I ALSO SEEM TO HAVE LOST MY GRIP OF THE THUMB AND INDEX FINGER TO HOLD A PEN. [/INST] Hi, Thank you for posting your query. Multiple neurofibromas may cause compression over the nerves to cause pain and weakness. You may take pregabalin or gabapentin capsules to relieve the pain. However, if neurofibromas are big, surgery may be required to remove them. Motor neuron disease (MND) may be treated with medications such as rissole, along with physiotherapy & exercises. However, MND can not be cured. If you can upload any MRI or EMG reports, they would help us in giving you further advice. Please get back if you require any additional information. Best wishes, Chat Doctor. Ly/ </s>