<s>[INST] Hi,I am constantly using depiwhite for an year now. It worked really well in improving my complexion. Is it harmful in any way? I read somewhere that skin whitening creams(which contain hydroquinone) are harmful and might lead to cancer.Please suggest me on this?Tell me good and bad effects of using DepiWhite cream..Thank you! [/INST] Hello, Welcome to Chat Doctor. I understand from your query that you are concerned about the long term side effects of definite cream. Depiwhite is a cream used to lighten hyperpigmentation and not to improve the general complexion. Your skin tone is determined at the time of your birth itself, and it is decided by the concentration of melanocytes and circulation. Therefore, any treatment or procedures can never make you fairer than what you were at the time of birth. But most of the people will acquire more pigmentation as age increases, we call it facultative pigmentation. Lot of factors determine it, most important being sunlight, others include dust, pollution, smoking, less HY Chat Doctor. Treatments should be to bring your pigmented skin back to your normal skin tone and make the skin tone even all over the face. Definite contain shy </s>