<s>[INST] My wife patient of depression since 2003 at starting sleeping prob and she was liking to have the foods. Afterwards went to doctors psychairitist but problem remains same even medicines are so heavy doses that she usd to sleep for continuously 2 days.then I was afraid and stopped the medicines for side effects.She is having two cycles being observed.Now presently only sleeping problem is there and huge energy she have.when she goes to bed for sleep ,sleep is far far away and starts  crying And after some time some sort of body irritation is there finally when she get down from bed she is fine.after havig meals or breakfast  again she feels bad and can not have the meals but she is hungry and wanted to eat.Another cycle she does not wanted to down from the bed and continuously sleeping , energyless,doesnot want to talk and not etching t.v.Even she does not like to talk to anyone.went so many doctorsPlease help [/INST] Hello, Thanks for choosing Chat Doctor for posting your query. I have gone through your question in detail and I can understand what you are going through. From what you have stated it is quite clear that she is having a depressive episode. Depression can occur with regular stress, and it can also occur biologically without any stress as well. She needs proper treatment for the same. There are various effective therapies for depression like fluoxetine, venlafaxine, bupropion, mirtazapine or Escitalopram, and they are all very effective and mostly safe. You may also require some benzodiazepines like clonazepam or lorazepam for a short period like 2-3 weeks to reduce the anxiety and help with your sleep.  If she is averse to the Chat Doctor.  This therapy is taken by either a psychologist or a psychiatrist in which the therapist identifies impaired cognitions (Thoughts) and try to correct them. They are 15-20 min weekly session and there should be around 8-10 sessions to help you with your illness. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. In future if you wish to contact me directly, you can use the below-mentioned link:bit.ly/ </s>