<s>[INST] my daughter is 4 & 1/2 mnth old she has seizures problem from last 2 months she has taken medication :-gardinal biotin levipil ebitoin . but still seizures coming after 45 minutes for 2-3 minutes every day & also 30-40 jerks every day due to this problem her physical growth is stop like headholding [/INST] Hi, welcome to our site. I am Chat Doctor, MD. Read your query. That is a very significant question and I appreciate your problem. I will try my best to answer your query At that high rate, I would, as a doctor admit her and treat her again till her seizures are well controlled there is no response to the medications, it can mean one of the following things1. The antiepileptic medicines have to be adjusted till the appropriate dose is reached for the patient. Till then the seizures can continue.2. The type seizure may have been wrongly identified. Till the right type of seizure is identified, the wrong medicine will be given, and hence seizure will continue.3. There may be some triggering event causing the seizure. Till that is removed, seizure may continue.4. The diagnosis may be wrong entirely, patient may have pseudoseizure (unlikely in your child)You really need to contact your neurologist and get her admitted and scanned. EEG and MRI need to be done. A correct diagnosis of the type of seizure need to be made and the appropriate medicine and its dose need to be achieved. I hope this helps you. Inform the reports mentioned above/if any other, so I can be of help further. I have given you the answer to the maximum considering the information provided. The results of the tests could further enhance my answer to you. Please do understand that some details could be extracted from a detailed history and examination. Please feel free to ask another query. I would be glad to help you. Looking forward to your return query with the details asked so that I can help you further. (If the answer has helped you, please indicate this)Best of luck. Chat Doctor. MBBS, MD (Internal Medicine), CC (Diabetes Mellitus), DNB (Neurology)Consultant Physician and DiabetologistJS Hospital Apollo Hospital, Delhi Baileys Hospital, Noida </s>