<s>[INST] My doctor wants to put me on niaspan since my liprotein a is 144, however my total cholosterol is 142, my good cholosterol is 50, I m 36 year old female, I m scared to take niaspan since it causes flushing, and can elevated my liver , my liver was at 61 elevated. I m 5 6 , 150 lbs, average good health, should I take it? Or is something else I can do. [/INST] Hi and welcome to Chat Doctor. I suggest OT to take it until your liver enzymes stabilize.it is much more important to protect your liver than to lower your lipids blood levels. So I am sure you can wait with Nissan bit more. Also try to find the cause of elevated liver enzymes such as fatty liver or hepatitis. You should treat it by changing dietary and lifestyle habits. Do exercise, avoid alcohol, smoking, fats, fast food and carbonated Chat Doctor.  Eat more fruit and vegetables, boiled meat and follow some of hepatoprotective diets. Findings usually improves on such measures. If not, then some medicines can be prescribed. Wish you good health. Regards </s>