<s>[INST] My sister she has pancreatic liver cancer what can I do. Its bad shes moved in to the morphine bills plus something call narco. What stage would you think shes in. Shes lost a kidney, portion of pancreas, liver. Now she is at 115lb and dropping. Again what stage do you feel she might be in? [/INST] Thanks for your question on Chat Doctor. In my opinion she is in stage 4 pancreatic cancer. In pancreatic cancer once patient is having metastases in distal organs like kidneys, lung, bones etc. than it is considered as stage 4 cancer, end stage cancer. Since your sister has kidney metastasis, involvement of distal organ, she is in end stage (4) disease. And no harm in taken morphine and other narcotics.  As in this stage palliative treatment in the form of centrally acting painkillers are Chat Doctor.  So continue morphine. Transdermal patch of fentanyl can be used as it gives pain relief for 72 hours. </s>