<s>[INST] I have post polio. I  recently completed ( 4 weeks ago) 192 hours of chemotherapy and 25 rounds of radiation.  I am having a very difficult time bouncing back.  Oncologist tells me the chemo is still working (my hair is still falling out but I am not getting my energy back. Could the post polio have something to do with this since i have a very high sensitivity to all drugs. [/INST] Hi, Thanks for writing in. Polio is a sequela of post infection paralysis to muscles of a limb. This is not related to chemotherapy or its outcome. The recovery after chemotherapy remains unaffected irrespective of whether a patient had polio. The polio is an irreversible paralysis due to an infection which you probably had during childhood. The manifestations of polio will no longer matter in the present scenario. Since you have weakness of muscles from before due to polio therefore it might take a little longer to get yourself in to normal physical work. This is not due to the effect of polio but a generalized reduced ability to adapt yourself for normal regular daily activities. Please do not worry. </s>