<s>[INST] hi I am 55 and my weight is close to 62 from last few months I am feeling numbness in my hand and thumb is most affected.I was working continuously with pressure on this thumb which I feel is the cause of this numbness. I have consullted a doctor and took few medicines too [/INST] Dear patient Numbness is restricted to thumb or outer 3 fingers?  If its involving thumb only it might be due to nerve root compression in cervical spine. If numbness is in outer three fingers possibility of carpet tunnel syn Chat Doctor.  This needs to be investigated with EMG NCV of involved upper limb to confirm diagnosis.  Meanwhile, start tab vitamin B12 plus pregabalin 75 mg at bedtime for relief of numbness. You need to consult expert orthopedic surgeon with report.  All the best. </s>