<s>[INST] My husband has suffered severe hypertension for years (with his bottom number never below 100, and his top number rarely under 200). For the past several months he has been taking several different blood pressure medicines, which will not lower it all. The only medicine that seems to lower it slightly and for only a few hours is Clonodine. He has seen a cardiologist who performed a nuclear stress test, to find his heart is normal, no blockages, but his left atrium is enlarged. So, the issue isnt his heart. In 2006, he was in a car accident and suffered traumatic brain damage and fractured his c2 and c3 vertabrae. Could this be related to his outrageous blood pressure? [/INST] Hi, Major mistake patients doing, or relative doing are they measuring the blood pressure with their own which can not be taken or granted for any treatment.  If the blood pressure here given is measured by cardiologist then it is okay, sometimes a single molecule is not enough to control the blood pressure and the second molecule need to be added. As you have asked about the C2 and C3, so it might not be the reason for high blood pressure or uncontrolled blood pressure, it is most advisable to get done the blood pressure reading with a physician. Hope I have answered your query. Let me know if I can assist you further. </s>