<s>[INST] MY WIFE IS HAVING THYROID BUT AND FROM LAST YEAR SHE ADDED DEPRESSION WITH IT. HER PROBLEMS IS SHE CHANGING HER MOODS FREQUENTLY. I.E. SOMETIMES SHE IS TELLING PLEASE PURCHASE FOR A LAND AND SOMETIMES SHE REITERATED TO MAKE A HOME AND SOME TIMES SHE STARTED TO GET OUT OF MY HOME. AND I AM STAYING IN ABROAD AND SHE IS STAYING AT HOME AND DOING A GOVT. JOB IN A SCHOOL. WHICH IS HER BEST JOB AND ENTERTAINMENT AT ALL. AND LIKE TO LISTEN MUSIC. ETC. AND SHE IS UNDER TREATMENT FOR PSYCHIATRIC IN KOLKATA . PLEASE HELP ME. [/INST] Hi there, Thanks for writing in. First thing to do is check if her thyroid problem is under control. Thyroid disorders sometimes present with depression. Once the thyroid disorder is treated, the depression might get cured. Another thing you can do is tell her to do regular exercise 5 days a week, as exercise releases endorphins in the body which might make her feel good. Also tell her to sign up for yoga or relaxation classes which will help her to relax, and might relieve her from depression. Hope this helps.  </s>