<s>[INST] Hi! My brother recently commited suicide and the autopsy revealed he had liver cancer that spread to his brain. I looked into a lab test done over 4 years ago to see if he had any indications back then of trouble. His AST was 183 and his ALT was 173. Albumin was OK at 4 and bilirubin 1.3 Is the fact that the ratio is over 1 indicative of cerrosis even thogh it is only slightly above 1? Are the values high enough to indicate definitely liver disease at that time? Thanks!!! [/INST] Hi, dairy have gone through your question. I can understand your concern. He has high AST and ALT.  They are liver enzymes and their level increase in any kind of liver damage.  It may be due to hepatitis, cirrhosis, alcohol, Chat Doctor.  So it needs complete liver function test with ultrasound abdomen. From that result we can not say that it is due to liver cancer.  But liver disease should be surely diagnosed and should further investigate. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using Chat Doctor. Wish you a very good health. </s>