<s>[INST] I was diagnosed with MGUS in my 40 s and am now 55.My oncologist told me it was to do with my T cells. I have not had a follow up for nearly 2 years and am feeling extremely fatigued and am currently experiencing severe groin pain and kidney pain. I have also been vomiting for no reason and blood literally pours from my nose when I ve been sick. Do you think this is related to the MGUS? I am sick of feeling tired all the time. [/INST] Hi, Thanks for writing in. These symptoms definitely seem to be related to your GUS which can invade your bone marrow and cause severe depletion of red cells, white cells and platelets. I definitely think you should get yourself evaluated by your oncologist. He would have to run several tests including a complete blood count, a bone marrow biopsy and a CT scan of the abdomen. Depending upon the extent of your disease, further treatment can be decided. Regards </s>