Several lines of evidence indicate lifestyle-induced hyperinsulinemia and reduced insulin function (i.e., insulin resistance) as a decisive factor in many disease states. For example, hyperinsulinemia and insulin resistance are strongly linked to chronic inflammation, which in turn is strongly linked to a variety of adverse developments such as arterial microinjuries and clot formation (i.e., heart disease) and exaggerated cell division (i.e., cancer). Hyperinsulinemia and insulin resistance (the so-called metabolic syndrome) are characterized by a combination of abdominal obesity, elevated blood sugar, elevated blood pressure, elevated blood triglycerides, and reduced HDL cholesterol. The negative impact of hyperinsulinemia on prostaglandin PGE1/PGE2 balance may be significant. COUNT 5
QSN1 Reduced insulin function can also go by what other term? ANS1 insulin resistance QSN2 Other than the reduced insulin function, what else contributes greatly to many disease states? ANS2 lifestyle-induced hyperinsulinemia QSN3 Arterial microinjuries and heart disease can all be linked back to which health issue that is caused by hyperinsulinemia? ANS3 chronic inflammation QSN4 The metabolic syndrome is a term that refers to which health issue? ANS4 insulin resistance QSN5 Hyperinsulinemia has a negative effect on the levels of which important molecules in the body? ANS5 prostaglandin PGE1/PGE2