Asthma is the result of chronic inflammation of the conducting zone of the airways (most especially the bronchi and bronchioles), which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. The narrowing is typically reversible with or without treatment. Occasionally the airways themselves change. Typical changes in the airways include an increase in eosinophils and thickening of the lamina reticularis. Chronically the airways' smooth muscle may increase in size along with an increase in the numbers of mucous glands. Other cell types involved include: T lymphocytes, macrophages, and neutrophils. There may also be involvement of other components of the immune system including: cytokines, chemokines, histamine, and leukotrienes among others. COUNT 5
QSN1 What is asthma the result of? ANS1 chronic inflammation of the conducting zone of the airways QSN2 What two airways are most effected by asthma? ANS2 the bronchi and bronchioles QSN3 In what ways do airways change? ANS3 an increase in eosinophils and thickening of the lamina reticularis QSN4 What other cell types are involced with the changing of airways? ANS4 T lymphocytes, macrophages, and neutrophils QSN5 What other components of the immune systems are included? ANS5 cytokines, chemokines, histamine, and leukotrienes among others