The girl was taken to the hospital Saturday in her Alpine hometown of Trento after she developed a high fever, according to the Italian newspaper, Corriere della Sera. No infected local mosquitoes were found, but lab tests showed two people had an identical strain of the disease. She was transferred to a hospital specializing in tropical diseases in neighboring Brescia, where she died in the early morning hours Monday, reports the daily newspaper. "This is the first time in 30 years of career that I have been involved in a case of native malaria in Trentino," Dr. Claudio Paternoster, an infectious disease specialist at Trento's Santa Chiara Hospital, told the newspaper. According to the European Centre for Disease Prevention and Control, there have been 75 cases of malaria linked to mosquitoes in luggage arriving in Western Europe from malaria-endemic countries in the past few decades. The child had never traveled abroad, but she had recently returned from a vacation in Bibione, a coastal resort northeast of Venice on the Adriatic Sea. The BBC reports that the child had previously been treated for her diabetes at the Trento hospital, where two other children were recovering from malaria they had caught in Africa. The ANSA news agency quoted the head of the Trento health service, Paolo Bordon, as saying that the child received no blood transfusions and that the malaria-infected children were being treated in other rooms with single-use equipment. Malaria is caused by a parasite that has a complex life cycle dependent on both animals, including humans, and mosquitoes.
– The death of a 4-year-old girl from malaria on Monday in Italy has local health authorities searching for answers and worrying about a resurgence of the deadly disease, NPR reports. Italy was declared malaria-free in 1970, and the mosquito that carries the disease no longer lives in the country. "It baffles us how she could have been infected,” NBC News quotes a doctor at a hospital in Trento as saying. Sofia Zago was brought to the hospital on Saturday with a high fever and quickly fell into a coma. Tests showed she had cerebral malaria, the deadliest form of the disease, and she died Monday after being moved to a hospital in Brescia. A doctor says it was the first case of native malaria he's seen in Trento in 30 years. "It's a mystery, almost impossible," the general manager of the provincial health service says regarding the case. Doctors believe Sofia may have been infected during a trip to a beach resort near Venice. It's possible she was infected by a mosquito that had managed to travel to Italy inside of luggage. It's also possible, though very unlikely, Sofia contracted the disease a few weeks ago when she was hospitalized for childhood diabetes. The BBC reports there were two children at the hospital at the same time recovering from malaria they picked up in Africa, though they were in a different ward and Sofia received no blood transfusions. Italy's health ministry has ordered an investigation, according to the AP. While Europe was declared malaria-free in 2015, there have been several individual cases of locally transmitted malaria in recent years, including one in Rome in 2009. (After decades of work, a malaria vaccine is finally here.)