"Ghetto Cowboy" is the lead single from the Mo Thugs album, "". The song is produced by Romeo Antonio and performed by Krayzie Bone and Layzie Bone, both of Bone Thugs-n-Harmony, along with new members of the Mo Thugs collective, Thug Queen and Powder P and a chorus by Layzie Bone's wife Felecia.
Thug Queen has performed with Bone Thugs-n-Harmony