The eigenvalues of the FIM represent the magnitudes of the sensitivities with respect to simultaneous variations of the parameters \(\mathbf {b}\) , and the relative magnitudes and directions of the variations are given by the corresponding eigenvectors. The FIM depends on the parametrization used. Suppose \(b_j=g_j(\theta _i), \: i=1,2,\dots ,s\) , then the FIM with respect to the parameter \(\mathbf {}\)  is [1]}:
\( \mathbf {F}(\mathbf {})=\mathbb {J}^\mathsf {T}\mathbf {F}(\mathbf {b})\mathbb {J}\) 
