Future theoretic development should help to predict, which of these contradictory answers will be
true for a given patient. Currently we are still unable to give such a prediction for individual
patients but the quasistatic theory achieves some success in predictions for groups and
populations [1]}, [2]}, [3]}, [4]}, [5]}, [6]}, [7]}, [8]}, [9]}, [10]}, [11]}, [12]}, [13]}, [14]}, [15]}.
These authors proposed and tested a universal rule to investigate in practice the amount of stress sensed by the system (and thus the danger of catastrophic changes).
The apparent universality of the top-down models of adaptation could
sometimes help in the solution of the important general problem of anticipation of
critical transitions [16]} and we should also try to apply these
models in general settings.
