Once the mesh is created, we model the time-dependent transmission of the viral load as a scalar transport equation that is advected by a statistically steady-state flow field obtained from the solution of coupled Navier–Stokes and Heat transfer solver. The well-established Variational Multiscale (VMS) FEM [1]} is used for the discretization. Dendro-KT interfaces with PETSc for solving the system of equations. We have recently extensively validated and demonstrated the capabilities of this framework  [2]}, [3]}.
