Pore-C is a sequencing technique designed to capture structural features of chromosome architecture inside the nucleus [1]}. It is the most recent extension of chromosome conformation capture (3C) technologies [2]}. Pore-C data contains multi-way contacts indicating sets of genomic loci that are colocalized in the nucleus. This reveals insight into the higher-order spatial organization and unfolding of chromosomes.
The advent of Pore-C allows for the capture of multi-contact data that more precisely represents the state of the nucleus.
