We now evaluate the isotropic TV model with two discrete differential operator definitions on a physically realistic three dimensional head model. This was created from T1-weighted MPRAGE scans acquired by Eggebrecht et al [1]} using the process described by Wu et al [2]} in which Statistical Parametric Mapping (SPM) software[3]} was used to perform parametric segmentation of five tissue types (scalp, skull, cerebrospinal fluid (CSF), gray matter, white matter) based on the pixel intensity probability function distribution. The five layers were processed in NIRFAST to create masks and layered volumetric FEM meshes. The reconstruction mesh consists of 50721 nodes associated with 287547 tetrahedral elements, with the average element size 9.2676mm\(^{3}\) . Each node is labeled by one of the five segmented head tissue types. Absorption coefficients assigned to each layer are from an in vivo study [4]} at 750nm (Table REF ).
