The OPES bias uses adaptive kernel bandwidth and is updated every 1000 time steps in the case of NaCl and every 500 for CO\(_2\) , while the barrier parameter is set to 600 and 200 kJ/mol respectively.
All simulations were carried out in GROMACS-2019.4 software[1]} patched with a private version of the PLUMED2.7-dev plugin.[2]} The in-house built codes and input files that were used in this work are available at PLUMED-NEST (...), a public repository of the PLUMED consortium.[3]} The figures were prepared using the Visual Molecular Dynamics (VMD) software.[4]}
