Melanoma PBN \(N\) =28.  We consider a PBN of size 28 from the same metastatic melanoma gene data [1]}. We use the exact same genes also studied in [2]}, for the purpose of direct comparison. Intervention in this case blueconcerns perturbations on the pirin gene, and the objective is to arrive at a subset of network states where another gene, namely WNT5A, is OFF. The state space (just under 270 million states) makes calculating attractors prohibitive. Like [3]}, [2]}, we compute the steady state distribution (SSD) instead. To control such a network we aim to increase the mass probability of the network ending up in a desirable state.
