"Copenhagen Denmark July    Researchers from the Department of Nutrition Exercise and Sports at the University of Copenhagen today announced the findings from a weight loss biomarker study published in the American Journal of Clinical Nutrition AJCN. The study Pretreatment fasting plasma glucose and insulin modify dietary weight loss success results from  randomized clinical trials found that fasting blood sugar andor fasting insulin can be used to select the optimal diet and to predict weight loss particularly for people with prediabetes or diabetes. The research analyzed data from three diet clinical trials which collectively looked at more than  individuals  Diet Obesity and Genes DiOGenes the OPUS Supermarket intervention SHOPUS and the Nutrientgene interactions in human obesity NUGENOB. The findings suggest that for most people with prediabetes a diet rich with vegetables fruits and wholegrains should be recommended for weight loss and could potentially improve diabetes markers. For people with type  diabetes the analysis found that a diet rich in healthy fats from plant sources would be effective for achieving weight loss. These diets could also be effective independent of caloric restriction.  Two simple biomarkers with a large effect Recognizing fasting plasma glucose as a key biomarker enables a new interpretation of the data from many previous studies which could potentially lead to a breakthrough in personalized nutrition said Arne Astrup M.D. Head of Department of Nutrition Exercise and Sports at University of Copenhagen. The beauty of this concept is its simplicity. While we are looking into other biomarkers it is quite amazing how much more we can do for our patients just by using those two simple biomarkers. We will continue to participate in and support research to explore additional biomarkers such as gut microbiota and genomics approaches which may offer more insights and help to more effectively customize the right diet for specific individuals.  The latest findings as reported in AJCN have garnered international support with further analysis conducted by researchers from the University of Colorado Tufts University and Centro de Investigacin Biomdica en Red de Fisiopatologa de la Obesidad y Nutricin CIBER OBN. Presented at the American Diabetes Associations th Scientific Sessions on June   the additional research includes an examination of patients in the Prevencion Dieta Mediterranea PREDIMED Study a Randomized Trial of a LowCHO Diet for Obesity CHO Study and The Healthy Weight for Living Study. The different studies six in total employed a variety of nutrition strategies including caloric restriction and ad libitum diets varying the contributions of carbohydrate and fat and increasing fiber intake.  The study was inspired by a finding in an early trial of Gelesis a novel hydrogel which demonstrated pronounced weight loss in people with prediabetes. The latest findings as published in AJCN concluded that a personalized nutritional approach based on an individuals biomarkers will lead to improved weight loss and maintenance success. The University of Copenhagen will continue to collaborate with the studys authors and other experts to advance this research and help find solutions for people around the world who struggle with weight loss. About the University of Copenhagen  With over  students and more than  employees the University of Copenhagen is the largest institution of research and education in Denmark. The purpose of the University  to quote the University Statute  is to conduct research and provide further education to the highest academic level. Approximately one hundred different institutes departments laboratories centres museums etc. form the nucleus of the University. The Department of Nutrition Exercise and Sports conducts research education innovation and dissemination of information in nutrition human physiology and sports at the highest international level and incorporates the humanities as well as health and social sciences."