"Updated  Almost sixty years since the FDA approved the pill for birth control in women a male version may finally be on the horizon. Researchers have developed a prototype male pill that appears to be safe in a monthlong trial. More attractive to many men than a longacting injection or topical gelboth of which are in developmentthe prototype pill offers a major step forward in male contraception Stephanie Page a professor at the University of Washington in Seattle and senior investigator on the study said in a statement https The oncedaily prototype pill suppressed certain hormones to the low levels youd expect to see with effective longerterm contraceptives results from an ENDO  the Endocrine Societys annual meeting in Chicago abstract show http The prototype pilldimethandrolone undecanoate DMAUis somewhat similar to the combined female pill which contains estrogen and a steroid hormone. Rather than estrogen DMAU uses a male hormone like testosterone. Currently available forms of testosterone can exit the body too quickly for use in a oncedaily pill. The undecanoate in DMAU however is a longchain fatty acid that can slow the drugs journey out of the body Page said. Eightythree men took various doses of DMAU or a placebo for a month. Researchers analyzed the mens hormones and cholesterol with blood tests at the start and end of the study. They found testosterone and two hormones needed for the production of sperm were notably suppressed in men who took the highest dose of DMAU. While some subjects on all doses experienced mild weight gain and decreases in socalled good HDL cholesterol DMAU appeared safe. All participants passed safety tests including liver and kidney health checks. Despite having low levels of circulating testosterone very few subjects reported symptoms consistent with testosterone deficiency or excess Page said. There were no significant changes in mood or sexual function but a minority of participants did experience decreased libido during the study.  Page has high hopes for the results calling them unprecedented in the development of a prototype male pill. Longerterm studies are the next step toward a oncedaily male contraceptive pill she said. The study was funded by the National Institutes for Health https This article has been updated to include more information on DMAU."