Nariman Bomanshaw Mehta, was an Indian-born American organic chemist and pharmacologist who designed, synthesized, and patented which organic compound, medication primarily used as an antidepressant and smoking cessation aid?
Nariman Mehta Nariman Bomanshaw Mehta (April 8, 1920 – August 22, 2014) was an Indian-born American organic chemist and pharmacologist who designed, synthesized, and patented the organic compound Bupropion, marketed under the name Wellbutrin as an antidepressant and smoking cessation aid.
RS-102221 RS-102221 is a drug developed by Hoffmann–La Roche, which was one of the first compounds discovered that acts as a potent and selective antagonist at the serotonin 5-HT receptor, with around 100x selectivity over the closely related 5-HT and 5-HT receptors. It has anxiolytic effects in animal studies, increases the effectiveness of SSRI antidepressants, and shows a complex interaction with cocaine, increasing some effects but decreasing others, reflecting a role for the 5-HT receptor in regulation of the dopamine signalling system in the brain.