What acute metabolic condition can be defined by the elevation of a yellow compound that occurs in normal catabolic pathway that breaks down heme in vertebrates?
Zieve's syndrome Zieve's syndrome is an acute metabolic condition that can occur during withdrawal from prolonged alcohol abuse. It is defined by hemolytic anemia (with spur cells and acanthocytes), hyperlipoproteinaemia (excessive blood lipoprotein), jaundice (elevation of unconjugated bilirubin), and abdominal pain. The underlying cause is liver delipidization. This is distinct from alcoholic hepatitis which, however, may present simultaneously or develop later.
Hemopexin Hemopexin (or haemopexin; HPX), also known as beta-1B-glycoprotein is a protein that in humans is encoded by the "HPX" gene and belongs to hemopexin family of proteins. Hemoglobin and its scavenger protein hemopexin (Hx) associate with HDL and influence the inflammatory properties of HDL. In addition it can also be said that HDL from Hx-null mice is proinflammatory. Moreover, Hemopexin deficiency is associated with various other inflammatory diseases such as septic shock and experimental autoimmune encephalomyelitis.