Nariman Bomanshaw Mehta, was an Indian-born American organic chemist and pharmacologist who designed, synthesized, and patented which organic compound, medication primarily used as an antidepressant and smoking cessation aid?
Nariman Mehta Nariman Bomanshaw Mehta (April 8, 1920 – August 22, 2014) was an Indian-born American organic chemist and pharmacologist who designed, synthesized, and patented the organic compound Bupropion, marketed under the name Wellbutrin as an antidepressant and smoking cessation aid.
EMDT 2-Ethyl-5-methoxy-"N","N"-dimethyltryptamine (EMDT) is a tryptamine derivative which is used in scientific research. It acts as a selective 5-HT receptor agonist, with a K of 16 nM, and was one of the first selective agonists developed for this receptor. EMDT inhibits both short- and long-term memory formation in animal studies, and this effect can be reversed by the selective 5-HT antagonist SB-399,885. Additionally, it is active in the tail suspension test, suggesting that it could be an effective antidepressant.