Dazzling Mirage was a Nigerian film that tells a story about what inherited blood disorder?
Dazzling Mirage Dazzling Mirage is a 2014 Nigerian drama film, produced and directed by Tunde Kelani; it stars Kemi "Lala" Akindoju, Kunle Afolayan, Bimbo Manuel, Yomi Fash Lanso, Taiwo Ajai-Lycett and Seun Akindele. It also features special appearances from Adewale Ayuba, Sean Tizzle, Tunde Babalola and Steve Sodiya. The film is an adaptation of a novel of the same name by Olayinka Abimbola Egbokhare, adapted to screen by Ade Solanke. It tells the story of a young sickle-cell patient and the various social and emotional challenges she is faced with.
Leber's hereditary optic neuropathy Leber's hereditary optic neuropathy (LHON) or Leber optic atrophy is a mitochondrially inherited (transmitted from mother to offspring) degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; this affects predominantly young adult males. LHON is only transmitted through the mother, as it is primarily due to mutations in the mitochondrial (not nuclear) genome, and only the egg contributes mitochondria to the embryo. LHON is usually due to one of three pathogenic mitochondrial DNA (mtDNA) point mutations. These mutations are at nucleotide positions 11778 G to A, 3460 G to A and 14484 T to C, respectively in the ND4, ND1 and ND6 subunit genes of complex I of the oxidative phosphorylation chain in mitochondria. Men cannot pass on the disease to their offspring.