What drug is the main ingredient referenced in the "drank" of the song Drank in My Cup?
Purple drank Purple drank is a slang term for a concoction which includes a prescription-strength cough syrup used in a manner inconsistent with its labeling, thus making it a recreational drug. The mixture became popular in the hip hop community in the southern United States in the 1990s, originating in Houston.
Depressant A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain. Depressants are also occasionally referred to as "downers" as they lower the level of arousal when taken. Stimulants or "uppers" increase mental and/or physical function, hence the opposite drug class of depressants is stimulants, not antidepressants.