What drug is the main ingredient referenced in the "drank" of the song Drank in My Cup?
Purple drank Purple drank is a slang term for a concoction which includes a prescription-strength cough syrup used in a manner inconsistent with its labeling, thus making it a recreational drug. The mixture became popular in the hip hop community in the southern United States in the 1990s, originating in Houston.
Tofenacin Tofenacin (INN; Elamol, Tofacine, Tofalin), or tofenacin hydrochloride (USAN), also sometimes called "mono"-"N"-desmethylorphenadrine, is an antidepressant drug with a tricyclic-like structure which was developed and marketed in the United Kingdom and Italy in 1971 and 1981, respectively, by Brocades-Stheeman & Pharmacia (now part of Astellas Pharma). It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. In addition to its use as a pharmaceutical medication, tofenacin is the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients.