What is the virus that is viral fever of humans and primates and that Triazavirin could have a potential application?
Ebola virus disease Ebola virus disease (EVD), also known as Ebola hemorrhagic fever (EHF) or simply Ebola, is a viral hemorrhagic fever of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. Then, vomiting, diarrhea and rash usually follow, along with decreased function of the liver and kidneys. At this time, some people begin to bleed both internally and externally. The disease has a high risk of death, killing between 25 and 90 percent of those infected, with an average of about 50 percent. This is often due to low blood pressure from fluid loss, and typically follows six to sixteen days after symptoms appear.
Reoviridae Reoviridae is a family of viruses. They have a wide host range, including vertebrates, invertebrates, plants, and fungi. They are unique in that they lack lipid envelopes and package their genomes of discrete double-stranded segments of RNA within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses (diameter,∼600–1,000 nm) to be obtained. There are currently 87 species in this family, divided among 30 genera. Reoviruses can affect the gastrointestinal system (such as "Rotavirus") and respiratory tract. The name "Reo-" is derived from "respiratory enteric orphan viruses." The term "orphan virus" refers to the fact that some of these viruses have been observed not associated with any known disease. Even though viruses in the Reoviridae family have more recently been identified with various diseases, the original name is still used.