What are two of the trade names of the medication designed, synthesized, and patented by Indian-born American organic chemist and pharmacologist Nariman Bomanshaw Mehta?
Bupropion Bupropion is a medication primarily used as an antidepressant and smoking cessation aid. It is marketed as Wellbutrin and Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States and Canada, although in many countries this is an off-label use. It is an effective antidepressant on its own, but is also popular as an add-on medication in cases of incomplete response to first-line SSRI antidepressants. Bupropion is taken in tablet form and is available only by prescription in most countries.
Solriamfetol Solriamfetol (developmental code names JZP-110, ADX-N05, others) is a norepinephrine–dopamine reuptake inhibitor (NDRI) which is under development by Jazz Pharmaceuticals for the treatment of narcolepsy, sleep apnea, hypersomnia, and renal failure. It is a low-potency NDRI, with respective IC values for the dopamine and norepinephrine transporters of 2.9 and 4.4 μM, and shows a low abuse liability. As of July 2017, it is in phase III clinical trials for narcolepsy and sleep apnea, phase II clinical trials for hypersomnia, and phase I clinical trials for renal failure.