Harvey Itano used electrophoresis to demonstrate the difference between normal hemoglobin and sickle cell hemoglobin in collaboration with a chemist born in what year?
Harvey Itano Harvey Akio Itano (November 3, 1920 – May 8, 2010) was an American biochemist best known for his work on the molecular basis of sickle cell anemia and other diseases. In collaboration with Linus Pauling, Itano used electrophoresis to demonstrate the difference between normal hemoglobin and sickle cell hemoglobin; their 1949 paper "Sickle Cell Anemia, a Molecular Disease" (coauthored also with S. J. Singer and Ibert C. Wells) was a landmark in both molecular medicine and protein electrophoresis.
Joseph S. Fruton Joseph Stewart Fruton (May 14, 1912 – July 29, 2007), born Joseph Fruchtgarten, was a Jewish Polish-American biochemist and historian of science. His most significant scientific work involved synthetic peptides and their interactions with proteases; with his wife Sofia Simmonds he also published an influential textbook, "General Biochemistry" (1953; 1958). From 1970 until his death, Fruton worked extensively on the history of science, particularly the history of biochemistry and molecular biology.