What medication sold under the name Adrucil uses the phenomenon of Thymineless death?
Thymineless death Thymineless death is the phenomenon by which bacteria, yeasts and mammalian cells undergo cell death when they are starved of thymidine triphosphate (dTTP), an essential precursor for DNA replication. This phenomenon underlies the mechanism of action of several antibacterial, antimalarial and anticancer agents, such as Trimethoprim, Sulfamethoxazole, Methotrexate and Fluorouracil.
Enciprazine Enciprazine (INN, BAN; enciprazine hydrochloride (USAN); developmental code names WY-48624, D-3112), is an anxiolytic and antipsychotic of the phenylpiperazine class which was never marketed. It shows high affinity for the α-adrenergic receptor and 5-HT receptor, among other sites. The drug was initially anticipated to produce "ortho"-methoxyphenylpiperazine (oMeOPP), a serotonin receptor agonist with high affinity for the 5-HT receptor, as a significant active metabolite, but subsequent research found this not to be the case.