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Do not take more than eight Midol PMS capsules in a 24 hour period. Each Midol PMS tablet contains 500 milligrams (mg) of acetaminophen. The recommended daily adult dose for acetaminophen is four grams (4000 mg), or 1000 mg in a single dose.
It is recommended that the dose then be doubled every second week up to a maximum. target dose of 190 mg AFT-METOPROLOL CR once daily (or to the highest tolerated dose). During long-term treatment the aim should be to reach 190 mg AFT-METOPROLOL CR. once daily (or the highest tolerated dose).