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exotoxin exÂ·oÂ·toxÂ·in (Äk'sÅ-tÅk'sÄ­n) n. A toxin secreted by a microorganism and released into the environment in which it grows. Also called extracellular toxin.
Endotoxins are small, stable, bacterially-derived hydrophobic molecules which can easily contaminate labware and whose presence can significantly impact both in vitro and in vivo experiments.2 Their presence is detected by the limulus amebocyte lysate (LAL) assay which can detect down to 0.01 Endotoxin Units (EU)/ml.