Ciliate conjugation is a sexual phenomenon that results in genetic recombination and nuclear reorganization within the cell. In most ciliate groups, however, the cells separate after conjugation, and both form new macronuclei from their micronuclei.
Before the bun, hamburgers are said to have been served between two pieces of bread. In fact, a ground beef patty was known as Hamburger steak (first mentioned in an American cookbook in 1891); when this was put between bread or in a bun it was called a Hamburger sandwich.
One claim of inventing the Hamburger sandwich comes from Charlie Nagreen of Seymour, Wisconsin, U.S.. In 1885, he tried selling fried meatballs at a county fair, but customers found them hard to eat while walking around the fair, so Nagreen flattened it and made it into a sandwich he called the âhamburgerâ.