An IRB/IEC should have: 1  At least five members. 2  Members with varying backgrounds. 3  At least one member must represent a non-scientific area (a lay member) 4  At least one member must not be affiliated with the institution or the trial site (an independent member)
Vesicles and Vacuoles Vesicles and vacuoles are membrane-bound sacs that function in storage and transport. Vacuoles are somewhat larger than vesicles, and the membrane of a vacuole does not fuse with the membranes of other cellular components. Vesicles can fuse with other membranes within the cell system (Figure 1).
The membrane enclosing the vesicle is also a lamellar phase, similar to that of the plasma membrane, and vesicles can fuse with the plasma membrane to release their contents outside of the cell.Vesicles can also fuse with other organelles within the cell.Vesicles perform a variety of functions.Because it is separated from the cytosol, the inside of the vesicle can be made to be different from the cytosolic environment.For this reason, vesicles are a basic tool used by the cell for organizing cellular substances. Vesicles are involved in metabolism, transport, buoyancy control, and enzyme storage.esicles can also fuse with other organelles within the cell. Vesicles perform a variety of functions. Because it is separated from the cytosol, the inside of the vesicle can be made to be different from the cytosolic environment.