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exotoxin exÂ·oÂ·toxÂ·in (Äk'sÅ-tÅk'sÄ­n) n. A toxin secreted by a microorganism and released into the environment in which it grows. Also called extracellular toxin.
Exotoxin: Induces high-titer antibodies called antitoxins, Endotoxin: Poorly antigenic. Bacterial endotoxins and exotoxins: Vaccines. Exotoxin: Toxoids used as vaccines, Endotoxin: No toxoids formed and no vaccine available. Bacterial endotoxins and exotoxins: Heat stability.xotoxin: Plasmid or bacteriophage, Endotoxin: Bacterial chromosome. Bacterial endotoxins and exotoxins: Toxicity (fatal dosage). Exotoxin: High (fatal dose on the order of 1 microgram), Endotoxin: Low (fatal dose on the order of hundreds of micrograms).