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Together, the glomerulus and Bowman's capsule make up the renal corpuscle of the nephron. These parts of the nephron filter blood and are vital to our body's survival.he glomerulus is a network of renal capillaries responsible for the filtration of blood. The glomerulus is supplied with blood by a small artery carrying unfiltered blood called the afferent arteriole.
The proximal tubule regulates the pH of the filtrate by exchanging hydrogen ions in the interstitium for bicarbonate ions in the filtrate; it is also responsible for secreting organic acids, such as creatinine and other bases, into the filtrate.n relation to the morphology of the kidney as a whole, the convoluted segments of the proximal tubules are confined entirely to the renal cortex. Some investigators on the basis of particular functional differences have divided the convoluted part into two segments designated S1 and S2.