If not corrected, blood flow in the penis becomes impeded by the increasingly constricting band of foreskin, which causes further swelling of the glans. Because lack of oxygen from the reduced blood flow can cause tissue death (necrosis), paraphimosis is considered a medical emergency and requires immediate treatment.
Allantoin is a major metabolic intermediate in many other organisms including plants and bacteria.llantoin is a major metabolic intermediate in many other organisms including plants and bacteria.
The active ingredients in comfrey herb are allantoin (a substance that fosters the growth of new cells), rosemarinic acid (an anti-inflammatory), and mucilage (a gummy substance that soothes inflammed tissues). Allantoin is credited with encouraging bone, cartilage, and muscle cells to grow.omfrey leaves have also caused cancer in experimental animals. Two species, S. asperum (prickly comfrey) and S. uplandicum (Russian comfrey) contain very high levels of echimidine, one of the more potent alkaloids. Adding to the problem is the fact that these varieties are sometimes labeled as âcommon comfreyâ.