Acute interstitial nephritis is an important cause of acute renal failure resulting from immune-mediated tubulointerstitial injury, initiated by medications, infection, and other causes. Acute interstitial nephritis may be implicated in up to 15 percent of patients hospitalized for acute renal failure.
The first player places one of their dominoes (right-side up) on the table. The second player tries to put a domino on the table that matches one side of what's already there. If a player cannot go, the player picks a domino from the pile and skips that turn. The chain of the played dominoes develops randomly, and can look a lot like a snake.
Most people play with a set of double six Dominoes. Double six Dominoes go up to six/six. They start at blank/blank and go up one/one, two/two, one/two, one/three, one/four all the way up to six/six. They also have double nine's, double twelve's. There is double eighteen's and double twenty two's but those are rare. The larger numbers are harder to keep count of but they are better for a large number of people playing. This is how to play a simple children's game of Dominoes. Everyone draws bones or bones or tiles until they have the Dominoes divided and then one Domino is set up in the middle and then each person looks at their Dominoes and then they play it so that it matches.