Acute interstitial nephritis is an important cause of acute renal failure resulting from immune-mediated tubulointerstitial injury, initiated by medications, infection, and other causes. Acute interstitial nephritis may be implicated in up to 15 percent of patients hospitalized for acute renal failure.
The first player places one of their dominoes (right-side up) on the table. The second player tries to put a domino on the table that matches one side of what's already there. If a player cannot go, the player picks a domino from the pile and skips that turn. The chain of the played dominoes develops randomly, and can look a lot like a snake.
These rules assume you are using a double-12 or double-9 set. (For a faster game with 2 to 4 players, use a double-9 set, or remove the 36 tiles with 10 or more pips from a double-12 set.) Object of the Game Be the first to play all of your dominoes, or at least as many high-point dominoes as possible, in each round.