An IRB/IEC should have: 1  At least five members. 2  Members with varying backgrounds. 3  At least one member must represent a non-scientific area (a lay member) 4  At least one member must not be affiliated with the institution or the trial site (an independent member)
Vesicles and Vacuoles Vesicles and vacuoles are membrane-bound sacs that function in storage and transport. Vacuoles are somewhat larger than vesicles, and the membrane of a vacuole does not fuse with the membranes of other cellular components. Vesicles can fuse with other membranes within the cell system (Figure 1).
Vacuoles are large vesicles that are derived from the Endoplasmic reticulum and Golgi apparatus. They are membrane- bound sacs and serve many functions such as storage. Animal cell vacuoles are much smaller and more numerous than plant cell vacuoles, because in plant cells, they store a great deal of water. If an animal cell performs phagocytosis, a food vacuole forms and fuses with a lysosome(containing enzymes) for furthering processing.