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The infusion time should not exceed 4 hours. Platelets, plasma and cryoprecipitate generally are transfused at a rate of 10 ml per minute. In order for a patient to receive maximum benefit platelets need to be transfused rapidly to get control of bleeding.
Typically one unit of random-donor platelets should increase the platelet count of a 70 kg adult by 5 x 109/L. [3] Response to platelet transfusions should be assessed by obtaining a platelet count 15 minutes to 1 hour posttransfusion and calculating the corrected count increment (CCI) as shown in the Figure.