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In the kidney, a renal corpuscle is the initial blood-filtering component of a nephron. It consists of two structures: a glomerulus and a Bowman's capsule. renal corpuscle is also known as a Malpighian corpuscle, named after Marcello Malpighi (1628â1694), an Italian physician and biologist. This name is not used widely anymore, probably to avoid confusion with a Malpighian corpuscle in the spleen.
The proximal tubule regulates the pH of the filtrate by exchanging hydrogen ions in the interstitium for bicarbonate ions in the filtrate; it is also responsible for secreting organic acids, such as creatinine and other bases, into the filtrate.n relation to the morphology of the kidney as a whole, the convoluted segments of the proximal tubules are confined entirely to the renal cortex. Some investigators on the basis of particular functional differences have divided the convoluted part into two segments designated S1 and S2.