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exotoxin exÂ·oÂ·toxÂ·in (Äk'sÅ-tÅk'sÄ­n) n. A toxin secreted by a microorganism and released into the environment in which it grows. Also called extracellular toxin.
EXOTOXINS. Exotoxins are heat labile proteins that are secreted by some species of bacteria and diffuse readily into the surrounding medium. In contrast to endotoxins, which are integral part of bacteria; exotoxins are actively synthesized and released.Exotoxins are produced by a variety of bacteria including gram-positive and gram-negative bacteria.In some species, most strains produce the same exotoxin while in others only a subset of strains produces a particular exotoxin.They are antigenic and can be toxoided.Their activity can be neutralized by antitoxins.xotoxins are produced by a variety of bacteria including gram-positive and gram-negative bacteria. In some species, most strains produce the same exotoxin while in others only a subset of strains produces a particular exotoxin. They are antigenic and can be toxoided. Their activity can be neutralized by antitoxins.