If not corrected, blood flow in the penis becomes impeded by the increasingly constricting band of foreskin, which causes further swelling of the glans. Because lack of oxygen from the reduced blood flow can cause tissue death (necrosis), paraphimosis is considered a medical emergency and requires immediate treatment.
Allantoin is a major metabolic intermediate in many other organisms including plants and bacteria.llantoin is a major metabolic intermediate in many other organisms including plants and bacteria.
In most marsupials, the allantois is avascular, having no blood vessels, but still serves the purpose of storing nitrogenous (NH 3) waste. Also, most marsupial allantoises do not fuse with the chorion. An exception is the allantois of the bandicoot, which has a vasculature, and fuses with the chorion.