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Januvia Substitutes. If JanuviaÂ® (sitagliptin) is not working for you, or if it is causing bothersome side effects, you may want to ask your healthcare provider about substituting another medication. Several alternatives to Januvia are available for type 2 diabetes. These include other oral diabetes drugs, such as:
An entire class of diabetes drugs can cause severe and disabling joint pain, the Food and Drug Administration cautioned patients on Friday. The drugs, which include Januvia, Onglyza, Tradjenta and Nesina, are all in the same class and work by making more insulin available to the body. Januvia was the first approved in the U.S. in 2006.