Excessive daytime sleepiness is one of the most common sleep-related patient symptoms, and it affects an estimated 20 percent of the population. Persons with excessive daytime sleepiness are at risk of motor vehicle and work-related incidents, and have poorer health than comparable adults. The most common causes of excessive daytime sleepiness are sleep deprivation, obstructive sleep apnea, and sedating medications. Other potential causes of excessive daytime sleepiness include certain medical and psychiatric conditions and sleep disorders, such as narcolepsy.
Some diseases are also associated with changes in the nails, which can include brittleness. Thin and brittle nails can be a sign of hypothyroidism, for example. The term onychoschizia refers to splitting of the fingernails as well as brittle or soft nails. Taking biotin (a vitamin) supplements can help in some cases of brittle nails, and application of moisturizers after soaking in water can also be of benefit. Medically Reviewed by a Doctor on 3/30/2015.
Modest benefits. Bisphosphonates are a proven remedy for preventing fractures in people with osteoporosis, but that benefit is relatively modest. A pivotal study, for example, found that 13.5 percent of women with the disease who took alendronate experienced a fracture compared with 18 percent of those who took a placebo.