An IRB/IEC should have: 1  At least five members. 2  Members with varying backgrounds. 3  At least one member must represent a non-scientific area (a lay member) 4  At least one member must not be affiliated with the institution or the trial site (an independent member)
Vesicles and Vacuoles Vesicles and vacuoles are membrane-bound sacs that function in storage and transport. Vacuoles are somewhat larger than vesicles, and the membrane of a vacuole does not fuse with the membranes of other cellular components. Vesicles can fuse with other membranes within the cell system (Figure 1).
Some freshwater protists have contractile vacuoles, a specialized form of vacuole that they use to manage water balance within the cell by pumping out excess water. Plant cells have very large vacuoles which function in storing nutrients and water within the cell. They can also serve a structural function by helping the plant cell to retain its shape through turgidity. Vesicles typically function through transportation of compounds within and between cells. Often, the substances within a vesicle will be cellular products or byproducts of a cells functioning. Typically vesicles function in much the same way in all cells. Vacuoles serve a variety of functions depending on the cell in which they are found. In most animal cells where vacuoles occur, they function in the temporary storage of food substances.