A sequela (UK: /sáµ»ËkwiËlÉ/, US: /sáµ»ËkwÉlÉ/; usually used in the plural, sequelae) is a pathological condition resulting from a disease, injury, therapy, or other trauma. Typically, a sequela is a chronic condition that is a complication which follows a more acute condition. It is different from, but is a consequence of, the first condition. Timewise, a sequela contrasts with a late effect, where there is a period, sometimes as long as several decades, between the resolution of the initial condition and the appearance of the late effect. In general, non-medical usage, the terms sequela and sequelae mean consequence and consequences. Examples and uses
Topic Overview. Uremia (uremic syndrome) is a serious complication of chronic kidney disease and acute kidney injury (also known as acute renal failure).It occurs when urea and other waste products build up in the body because the kidneys are unable to eliminate them.opic Overview. Uremia (uremic syndrome) is a serious complication of chronic kidney disease and acute kidney injury (also known as acute renal failure).
Urea or carbamide is an organic compound with the chemical formula C O (N H 2) 2. The molecule has two âNH 2 groups joined by a carbonyl (C=O) functional group.Urea serves an important role in the metabolism of nitrogen-containing compounds by animals, and is the main nitrogen-containing substance in the urine of mammals.It is colorless, odorless solid, highly soluble in water, and practically non-toxic (LD50 is 15 g/kg for rats).rea production occurs in the liver and is regulated by N-acetylglutamate. Urea is then dissolved into the blood (in the reference range of 2.5 to 6.7 mmol/liter) and further transported and excreted by the kidney as a component of urine.