There are other ways your doctor can look for the cause of your enlarged liver. He may use an ERCP, a scope that checks for problems in the ducts (tubes) that carry bile. An MRCP, a special type of MRI, also helps spot that kind of trouble.
Cholestasis is reduction or stoppage of bile flow. Disorders of the liver, bile duct, or pancreas can cause cholestasis. The skin and whites of the eyes look yellow, the skin itches, urine is dark, and stools may become light-colored and smell foul. Laboratory and often imaging tests are needed to identify the cause.
I know it has been years since this was posted, but there is a condition called cholestasis of pregnancy that causes an elevation of bile salts in the bloodstream and subsequent intense itching of the soles and palms, especially at night. Unfortunately, many times, this causes a fetus to die in utero suddenly.