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Do not take more than eight Midol PMS capsules in a 24 hour period. Each Midol PMS tablet contains 500 milligrams (mg) of acetaminophen. The recommended daily adult dose for acetaminophen is four grams (4000 mg), or 1000 mg in a single dose.
The dose may be adjusted every three to four days with increment of 50 mg/day. The maximum daily dose for outpatients is 400 mg/day in divided doses. Meanwhile, for patients within hospital settings (particularly those with severe depression) may be given a maximum of 600 mg/day in divided doses.