Acute interstitial nephritis is an important cause of acute renal failure resulting from immune-mediated tubulointerstitial injury, initiated by medications, infection, and other causes. Acute interstitial nephritis may be implicated in up to 15 percent of patients hospitalized for acute renal failure.
The first player places one of their dominoes (right-side up) on the table. The second player tries to put a domino on the table that matches one side of what's already there. If a player cannot go, the player picks a domino from the pile and skips that turn. The chain of the played dominoes develops randomly, and can look a lot like a snake.
There are many other possible games that can be played with a traditional domino set. Some of the games can be very complicated with lots of rules to remember! Not everyone uses dominoes to play these types of games, though. Many children prefer to use dominoes as toys that they can stack on end in long lines. If spaced properly, the first domino in the line can be tipped over, which causes the next domino in line to tip and so on and so forth.