Ciliate conjugation is a sexual phenomenon that results in genetic recombination and nuclear reorganization within the cell. In most ciliate groups, however, the cells separate after conjugation, and both form new macronuclei from their micronuclei.
Before the bun, hamburgers are said to have been served between two pieces of bread. In fact, a ground beef patty was known as Hamburger steak (first mentioned in an American cookbook in 1891); when this was put between bread or in a bun it was called a Hamburger sandwich.
Frank and Charles Menches are often credited with having invented the hamburger sandwich. The brothers, who lived in Ohio, were traveling concessionaires, selling ground pork sandwiches at county fairs. One day in 1885, so the story goes, they went to a butcher for ground pork, but he had run out of it.