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Do not take more than eight Midol PMS capsules in a 24 hour period. Each Midol PMS tablet contains 500 milligrams (mg) of acetaminophen. The recommended daily adult dose for acetaminophen is four grams (4000 mg), or 1000 mg in a single dose.
In one study, propranolol at a maximum dosage of 60 mg per day in three divided doses for children weighing less than 77 lb (35 kg), and 120 mg per day in three divided doses for children weighing 77 lb or more, produced a reduction in headache frequency of two thirds (NNT = 1.5; 95% CI, 1.15 to 2.10)., 11 For a migraine frequency reduction of 50 percent or more, authors of a Cochrane review 12 of anticonvulsants for migraine prophylaxis calculated a number needed to treat (NNT) of 3.1 (95% CI, 1.9 to 8.9) for sodium valproate and 4.8 (95% CI, 3.5 to 7.4) for divalproex.