Leg pain is also frequently a sign of injury, such as the following: Muscle strain is a common injury that happens when the muscle fibers tear as a result of overstretching. It often occurs in the larger muscles, such as the hamstrings, calves, or quadriceps.
medical Definition of superinfection : a second infection superimposed on an earlier one especially by a different microbial agent of exogenous or endogenous origin that is resistant to the treatment used against the first infection
Infection with HDV in a patient who is already positive for the hepatitis B surface antigen (HBsAg) is known as superinfection and results in fulminant liver failure in 5% of patients. Approximately 80-90% develop chronic HDV infection.