Muscle injuries and dehydration can also trigger cramps. Dehydration is the excessive loss of fluids in the body. Low levels of any of the following minerals that contribute to healthy muscle function may also cause muscle cramps: calcium.
The heart is a part of the cardiovascular system in fact its the main part so if you have heart disease another way of saying this is you have cardiovascular disease.
Each of these results of cardiovascular fitness/cardiorespiratory conditioning will have a direct positive effect on muscular endurance, and an indirect effect on strength and flexibility.