After the transcription factor binds the DNA, co-regulatory molecules will bind the transcription factor. As with the DBD, transcription factors do not bind to just any co-regulatory proteins.The TAD region of the transcription factor interacts with co-regulatory proteins and it too, has unique sequences.These sequences are only recognized by certain co-regulatory proteins.n summary, transcription factors regulate gene expression. They do this by interacting directly with a target gene through the DBD. Once the transcription factor binds to DNA, co-regulatory molecules bind the transcription factor at the TAD.
In order to successfully stain a deck, the surface must be completely dry and clear of debris. Working on a sunny day with no forecast for rain, start by sweeping deck with broom. TIP: New decks simply need sweeping prior to staining.
There is no need to put a sealer over good grade stains. Never put a sealer on before you stain, as it will block the stain from penetrating and adhering to the wood. Wait 24 hours before using your deck after staining. Don't stain if there is rain or temps under 50F predicted within 12 to 24 hours.