However, some people who have early-onset Alzheimer's don't have mutations in these three genes. That suggests that this early-onset form of Alzheimer's disease is linked to other genetic mutations that haven't been identified yet.
Early history Cigars, cigarettes Cancer by the carton Legal history Surgeon General's warning. (CNN) -- Tobacco was first used by the peoples of the pre-Columbian Americas. Native Americans apparently cultivated the plant and smoked it in pipes for medicinal and ceremonial purposes.
Tobacco can well be credited with making Jamestown the first permanent English colony in the New World. So tobacco has been a critical crop and an ingrained habit for many years, well before cigarettes were even invented.he Jamestown colonists had not found gold, nor a route to the South Seas, nor the Lost Colony of Roanoke Island. But they had found tobacco. Tobacco had brought the settlement from wretched failure to giddying success.