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The infusion time should not exceed 4 hours. Platelets, plasma and cryoprecipitate generally are transfused at a rate of 10 ml per minute. In order for a patient to receive maximum benefit platelets need to be transfused rapidly to get control of bleeding.
Aside from the procedure, donating platelets is different from donating blood in a few ways. Firstly, the donor must not take aspirin or other anti-platelet medications such as clopidogrel (Plavix) for anywhere from 36 to 72 hours prior to donation. (Guidelines vary by blood center.) The reason is that aspirin can prevent platelets from adhering to clot bleeding.