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In the kidney, a renal corpuscle is the initial blood-filtering component of a nephron. It consists of two structures: a glomerulus and a Bowman's capsule. renal corpuscle is also known as a Malpighian corpuscle, named after Marcello Malpighi (1628â1694), an Italian physician and biologist. This name is not used widely anymore, probably to avoid confusion with a Malpighian corpuscle in the spleen.
However, with the aid of the myogenic mechanism, the glomerular filtration rate remains very insensitive to changes in human blood pressure. Myogenic mechanisms in the kidney are part of the autoregulation mechanism which maintains a constant renal blood flow at varying arterial pressure. Concomitant autoregulation of glomerular pressure and filtration indicates regulation of preglomerular resistance.