However, it is a known DNA mutagen, and this in turn could lead to carcinogenic effects. Acrolein has also been been linked with heart disease as a contributor, and is one of the most abundant chemicals in cigarette smoke.
1 Steroid hormones pass through the cell membrane of the target cell. 2  The steroid hormone binds with a specific receptor in the cytoplasm. 3  The receptor bound steroid hormone travels into the nucleus and binds to another specific receptor on the chromatin.teroid hormones cause changes within a cell by first passing through the cell membrane of the target cell. Steroid hormones, unlike non-steroid hormones, can do this because they are fat-soluble.
Thus, the mechanism of action of steroid hormones is to modulate gene expression in target cells. By selectively affecting transcription from a battery of genes, the concentration of those respective proteins are altered, which clearly can change the phenotype of the cell.teroid and thyroid hormone receptors are members of a large group (superfamily) of transcription factors. In some cases, multiple forms of a given receptor are expressed in cells, adding to the complexity of the response.