1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Nodules on the joints of the hands: soft tissue swelling or bony distortion due to an inflammatory reaction. See detailed information below for a list of 24 causes of Nodules on the joints of the hands, Symptom Checker, including diseases and drug side effect causes.