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Lyme disease is caused by infection with Borrelia burgdorferi, a type of bacteria called a spirochete. In the eastern U.S., the infection is transmitted by the bite of a black-legged tick, Ixodes scapularis, commonly known as the deer tick. history of a known tick bite will help the doctor to know if Lyme disease is the cause of an illness. However, many people with Lyme disease do not remember being bitten by a tick. Deer ticks are tiny and often go unnoticed.
Three main species (Borrelia garinii, Borrelia afzelii, and B burgdorferi s.s.) are the main causative agents of the disease in humans, while a number of others have been implicated as possibly pathogenic. Borrelia species known to cause Lyme disease are collectively called Borrelia burgdorferi sensu lato (s.l.). Borrelia are microaerophilic and slow-growingâthe primary reason for the long delays when diagnosing Lyme diseaseâand have been found to have greater strain diversity than previously estimated.