Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
Females who carry the gene forhemophilia but are not affected with hemophilia are called âcarriers.âThe hemophilia gene can also occur in a male or a female as a result of spontaneous gene mutation. If this occurs, theabnormal gene may be passed from female âcarriersâ for several generations before hemophilia appears.