Peter Drier, a bank technology manager in New York City, was blindsided after neck surgery by a $117,000 bill from a doctor he did not recall meeting. Credit Joshua Bright for The New York Times.
Cushing's triad, which includes bradycardia, hypertension (with widened pulse pressure), and a change in respiratory pattern, is seen in head injuries with increased intracranial pressure (ICP).
Iatrogenic Cushing Syndrome - Background. 1  Cushing syndrome, first described by Harvey in 1912, refers to signs and symptoms caused by excess free plasma glucocorticoids. Excess glucocorticoids can be from increased endogenous production or prolonged exposure to exogenous use of glucocorticoid products. While endogenous Cushingâs syndrome is a rare disease, iatrogenic (drug-related or exogenous) Cushing syndrome from glucocorticoid products is commonly seen in clinical practice. This article will focuses on iatrogenic, or drug-related, Cushing syndrome. Drugs that have been reported to result in hypercortisolism are glucocorticoids, megestrol acetate, and herbal preparations that contain glucocorticoids.