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Seroquel Dosage for Bipolar Disorder. The dose of Seroquel for bipolar disorder varies, depending on the particular type of bipolar disorder. The recommended starting dose of Seroquel for bipolar depression (in adults only) is Seroquel 50 mg, taken once daily at bedtime.Your healthcare provider will generally increase your dose quickly within a few days, up to Seroquel 300 mg, taken once daily at bedtime.For bipolar mania in adults, the recommended starting dose of Seroquel is 50 mg, taken twice a day.In general, your healthcare provider will increase your dose quickly within a few days, if needed, up to Seroquel 400 mg twice daily.our healthcare provider will generally increase your dose quickly within a few days, up to Seroquel 300 mg, taken once daily at bedtime. For bipolar mania in adults, the recommended starting dose of Seroquel is 50 mg, taken twice a day.
For depression, probably from 75-300mg. For, schizophrenia, manufacturer recommended amount is 200-400mg. For bipolar, it really varies from 25-800mg depending on mood state, other meds, if it's maintenance, and how your body gets along with it.I've been taking 75mg with other medication. just now. Report Abuse. Posology and method of administration Seroquel should be administered twice a day, irrespective of the meals. Adults The daily dose for the first four days of therapy is 50 mg (1 Day), 100 mg (2 Day), 200 mg (3 Day) and 300 mg (4 Day).