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CVS is usually performed between 10 and 13 weeks from your last menstrual period. CVS may be chosen over amniocentesis because it may be performed earlier in the pregnancy. Chorionic villus sampling detects chromosome abnormalities (i.e. Down syndrome) and genetic disorders (i.e. cystic fibrosis.).
FYI, there is an alternative to amniocentesis that can be performed earlier in pregnancy called CVS. CVS has a somewhat higher risk of miscarriage (possibly as high as 1%), but can be performed as early as 10 weeks of pregnancy.mnio's only test for a few disorders/syndromes. If you have an ultrasound at 12 weeks, your doctor can tell you if there's reason to test further. I wouldn't recommend an amniocentesis.