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A full set of sister chromatids is created during the S subphase of interphase, when all the DNA in a cell is replicated. Identical chromosome pairs are separated into two different cells during mitosis, or cellular division.
Meiosis II is essentially the same division process as mitosis. Through the separation of the two sister chromatids, a total of four daughter cells, each with a haploid set of chromosomes, are created. Meiosis I. Meiosis must be preceded by the S phase of the cell cycle. This is when DNA replication (the copying of the genetic material) occurs.