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Antithyroid microsomal antibody is a test to measure antithyroid microsomal antibodies in the blood. Microsomes are found inside thyroid cells. The body produces antibodies to microsomes when there has been damage to thyroid cells. A blood sample is needed.
Staining of proximal tubules can be observerved on the kidney, whereas distal tubules remain unstained. Liver kidney microsomal type 1 antibody is an autoantibody associated with autoimmune hepatitis. Several subtypes of anti-liver-kidney microsome antibodies (LKM) are known. LKM-1 antibodies associated with autoimmune chronic active hepatitis recognize P450 2D6, a cytochrome P450 mono-oxygenase.