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Treatment side effects. A wide range of medication can cause a metallic taste in the mouth as a side effect. Examples are: 1  antibiotics (such as metronidazole). 2  antifungal medicine. 3  antihistamines. 4  chemotherapy. 5  diuretics. 6  steroid medication. 7  nicotine patches.
A metallic taste in the mouth can be unpleasant and is not that uncommon. There are several possible explanations for the condition ranging from those which can be easily remedied to more serious underlying medical problems. common cause is from bleeding, because the pigment in red blood cells contains iron. If you bite your tongue by accident, suffer trauma to the mouth, or have gum disease which can cause spontaneous bleeding from inflamed gums, then you will likely have a metal taste for a while, or notice it now and again.