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Freebase(0.00 / 0 votes)Rate this definition: Gynecomastia. Gynecomastia is the benign enlargement of breast tissue in males. It may occur transiently in newborns. Half or more of adolescent boys have some breast development during puberty.
Gynecomastia is enlargement of the gland tissue of the male breast. During infancy, puberty, and in middle-aged to older men, gynecomastia can be common.Gynecomastia must be distinguished from pseudogynecomastia or lipomastia, which refers to the presence of fat deposits in the breast area of obese men.icture of male on the left with no gynecomastia and the male on the right with gynecomastia. A number of medical conditions may also result in gynecomastia: 1  Malnutrition and re-feeding (recovery from malnutrition) have both been shown to create a hormonal environment that may lead to gynecomastia.