Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
Hemophilia can occur in all races and ethnic groups. What causes hemophilia? The genes that regulate the production of factors VIII and IX are found on the X chromosome only. Hemophilia is caused by mutations in either the factor VIII or factor IX gene on the X chromosome. If a woman carries the abnormal gene on one of her chromosomes (females have a pair of X chromosomes), she will not have hemophilia herself, but she will be a carrier of the disorder.