For thousands of years it was used by the ancient Egyptians as part of religious ceremonies to reach higher levels of consciousness and connect to the Divine. They would steep the Blue Lotus flowers in wine for several weeks and use it as a sacred sacrament.
1 Diseases of the veins in the liver. 2  Vascular diseases, such as Budd-Chiari syndrome, can cause blockages in the veins of the liver, leading to acute liver failure. 3  Metabolic disease. 4  Rare metabolic diseases, such as Wilson's disease and acute fatty liver of pregnancy, infrequently cause acute liver failure.
Acetaminophen toxicity is the most common cause of hepatic failure requiring liver transplantation in Great Britain. In the United States, acetaminophen toxicity has replaced viral hepatitis as the most common cause of acute hepatic failure and is the second most common cause of liver failure requiring transplantation. Acetaminophen metabolism occurs primarily in the liver and is illustrated in the image below.