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Biochemistry of Dog Coat Color. The color of a dogâs coat is determined by relative levels of two pigments: eumelanin, which can be either brown or black, and pheomelanin, which is yellow to orange or red. Both pigments are generated by metabolism of tyrosine. A schematic diagram of the pathway is below. Schematic of the melanin synthesis pathways.
In a breed of dog, for example, in which the gene for black coat colour is dominant over (suppresses the effect of) the gene for red coat colour, a dog with a black-coloured coat may be either pure breeding, with two genes for black coat colour, or hybrid, with one gene for black coat colour and one for red coat colour.