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However, the advice given by one of the manufacturers of metronidazole is that you should avoid drinking alcohol while taking it and for 48 hours after finishing the course. This makes sense because 48 hours is roughly the time it takes for metronidazole to be cleared from the body of an average adult. During this time, it may be sensible to also avoid cough and cold remedies and mouthwashes that contain alcohol.
These can be unpleasant, but drinking alcohol within three days of taking metronidazole can cause additional unwanted effects, too. The most common is face flushing (warmth and redness), but other possible effects include: abdominal pain. cramps. nausea and vomiting.