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Creatinine is a metabolic by-product of muscle metabolism, and normally appears in urine in relatively constant quantities over a 24 hour period with normal liquid intake. Therefore, urine creatinine can be used as an indicator of urine water content or as a marker identifying a specimen as urine. Greater than normal intake of water will increase the urine water content (lowering the creatinine level) consequently diluting the amount of drug in urine. Conversely, a limited intake of water can lead to an abnormally concentrated urine specimen (as occurs with dehydration) resulting in elevated creatinine levels.
There is no âtop endâ to the normal levels of creatinine in your urine, but if your urine tests too low for creatinine you will receive a âdilutedâ result. The normal range is anywhere from about 110 â 200, and it is common for labs to see a lot of levels in the 20 â 30ng/dL range.