1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Thyroid nodules are small growths or lumps that develop within the thyroid gland or on the surface of the gland. These nodes or nodules can eventually lead to thyroid overactivity and excessive thyroid hormones in the blood. Sometimes, an overactive thyroid is caused by misuse or abuse of thyroid medication.