In Pictures: Americaâs Safest Cities. Henderson, Nev., takes the No. 2 spot despite its location within the Metropolitan Statistical Area of Las Vegas-Paradise, which ranked ninth this year on Forbesâ list of Americaâs Most Dangerous Cities.
Use in Cancer. Recombinant human papillomavirus (HPV) quadrivalent vaccine is approved to prevent some conditions caused by certain types of HPV. It is used in males or females aged 9 to 26 years to prevent the following: 1  Anal cancer.2  Cervical cancer. 3  Vaginal cancer.4  Vulvar cancer.ecombinant human papillomavirus (HPV) quadrivalent vaccine is approved to prevent some conditions caused by certain types of HPV. It is used in males or females aged 9 to 26 years to prevent the following: 1  Anal cancer. 2  Cervical cancer. 3  Vaginal cancer. 4  Vulvar cancer.
A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity.he immunoprohylactic efficacy of L1 VLP vaccines, such as quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine, appear to be mediated by the development of humoral immune responses.