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Biochemistry of Dog Coat Color. The color of a dogâs coat is determined by relative levels of two pigments: eumelanin, which can be either brown or black, and pheomelanin, which is yellow to orange or red. Both pigments are generated by metabolism of tyrosine. A schematic diagram of the pathway is below. Schematic of the melanin synthesis pathways.
Chestnut and black are considered the base colors that all remaining coat color genes act upon. Bay (Agouti) is the most common modifier, restricting the black pigment to the points of the horse.There are a number of dilution genes that lighten these colors in a variety of ways, sometimes affecting skin and eyes as well as hair coat, including cream, dun, pearl, champagne and silver dapple.hestnut and black are considered the base colors that all remaining coat color genes act upon. Bay (Agouti) is the most common modifier, restricting the black pigment to the points of the horse.