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The rash from shingles will heal in 1 to 3 weeks and the pain or irritation will usually go away in 3 to 5 weeks. When shingles occurs on the head or scalp, the symptoms usually go away eventually, but it may take many months. Put cool, moist washcloths on the rash. 2  Rest in bed during the early stages if you have fever and other symptoms. 3  Try not to let clothing or bed linens rub against the rash and irritate it. 4  Call your healthcare provider right away if: You develop worsening pain or fever.
Proper Use. Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine. Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear. If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day. Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach. Acyclovir is best taken with a full glass (8 ounces) of water.