Hyponyms (each of the following is a kind of lacrimator): chlorobenzylidenemalononitrile; CS gas (a tear gas that is stronger than CN gas but wears off faster; can be deployed by grenades or cluster bombs; can cause skin burns and fatal pulmonary edema)
Freebase(0.00 / 0 votes)Rate this definition: Renin. Renin, also known as an angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system âalso known as the renin-angiotensin-aldosterone axisâthat mediates extracellular volume, and arterial vasoconstriction.
Renin is an aspartic protease that is synthesized in the juxtaglomerular cells of the kidney. Renin cleaves angiotensinogen â a protein synthesized principally in the liver â to produce the decapeptide angiotensin I, which is biologically inactive (Fig. 1).