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Prednisone is prescribed for a client with diabetes mellitus who is taking Humulin NPH insulin daily. Which prescription change does the nurse anticipate during therapy with the prednisone? a) An additional dose of prednisone daily b) A decreased amount of daily Humulin NPH insulin c) An increased amount of daily Humulin NPH insulin d) The addition of an oral hypoglycemic medication daily Pharmacology NCLEX Practice Questions Answers and Rationale 31) C
A: Prednisone is a corticosteroid medication which is used to treat various inflammatory conditions including temporary use for relief of allergic reactions. Side effects associated with short term use of prednisone include insomnia, stomach upset, mood changes, increased appetite, and weight gain.: I have prednisone induced diabetes. A: Some of the side effects of prednisone may include: headache, mood changes, thin skin, acne, diabetes, loss of bone mass, glaucoma, and fluid retention. Prednisone may alter glucose regulation which can lead to high blood sugar.