Sertraline should not be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (NardilÂ®), tranylcypromine (ParnateÂ®), isocarboxazid (MarplanÂ®), rasagiline (AzilectÂ®), and selegiline (EmsamÂ®).
Pure caffeine is a white, tasteless substance that makes up as much as 5% of. the weight of tea leaves. By structure, caffeine is closely related to the purine bases, guanine and adenine, found in deoxyribonucleic acids (DNA).
It was of course assumed, since these beverages had a distinct effect upon the body, that they contained some active principle.. In 1821, a white, silky substance, odorless and bitter to the taste, was extracted from coffee and named caffeine. Six years later, the same substance was found to exist in tea.