Often, for gene transcription to occur, a number of transcription factors must bind to DNA regulatory sequences. This collection of transcription factors, in turn, recruit intermediary proteins such as cofactors that allow efficient recruitment of the preinitiation complex and RNA polymerase.ranscription factors use a variety of mechanisms for the regulation of gene expression. These mechanisms include: 1  stabilize or block the binding of RNA polymerase to DNA. 2  catalyze the acetylation or deacetylation of histone proteins.
The best time to take this, and other statin anti-cholesterol meds, is about 6pm in the evening. This has nothing to do with meals. Rather, it's best to get the drug in your â¦ system when cholesterol is being made in the body by the liver, which occurs between 6pm and midnight.+ 3 others found this useful.he best time to take this, and other statin anti-cholesterol meds, is about 6pm in the evening. This has nothing to do with meals. Rather, it's best to get the drug in your â¦ system when cholesterol is being made in the body by the liver, which occurs between 6pm and midnight. + 3 others found this useful.
Some general considerations for when and how to take pantoprazole include the following: 1  The medication comes in tablets and in oral granule packets. It is usually taken once or twice a day. 2  You can take the tablets with or without food. Pantoprazole granules should be taken 30 minutes before a meal. Do not split, chew, or crush pantoprazole tablets. Pantoprazole suspension comes as dry granules in individual packets. The contents of one packet should be sprinkled on a spoonful of applesauce or mixed with a teaspoon of apple juice.