The first step to shopping smart is reviewing the top 10 baby wipe brands to consider, including the various options each brand has to offer and the advantages and disadvantages of each. Depending on an individual baby's needs, one brand of baby wipe may be more appropriate than others.
There are two main strategies for the induction of transcription: a strong promoter is negatively controlled by a repressor protein and induction of transcription is effected by an inducer (a ligand that inactivates the repressor).
ATF6 is an endoplasmic reticulum (ER) transmembrane transcription factor that is activated by the ER stress/unfolded protein response by cleavage of its N-terminal half from the membrane. We find that ER stress induces ATF6 to move from the ER to the Golgi, where it is cut in its luminal domain by site 1 protease.irst, deletion of various regions of the luminal domain abolished ER stress induction of GAL4-ATF6 constructs, translocation to the Golgi, and cleavage. Second, the luminal domain was necessary and sufficient for translocation of ATF6 from the ER to the Golgi.