Cell Wall & Gram classification â¢ Most bacteria fall into one of two groups: Gram-positive or Gram-negative â¢ Based on results of a differential staining test (the Gramâs stain) â¢ Primary basis for this distinction is differences in their cell walls Cell Wall: structure & composition Peptidoglycan (murein) â¢ Most importantcomponent
Chlorhexidine is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. The physiologic effect of chlorhexidine is by means of Decreased Cell Wall Integrity. Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity.
BSI = bloodstream infection; CHG = chlorhexidine gluconate; ICU = intensive care unit; SSI = surgical site infection. In our never-ending attempt to vanquish healthcare-associated infections, the latest weapon to emerge is chlorhexidine gluconate (CHG).Not that CHG is exactly new: as an antiseptic, it has been around for more than 50 years.HG will eliminate visible dirt, according to our experts, and routine pre-bathing with soap and water is not needed unless a patient is significantly soiled. In that sense, CHG will never entirely replace soap and water cleaning.