Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
Another form of the disorder, known as acquired hemophilia, is not caused by inherited gene mutations. This rare condition is characterized by abnormal bleeding into the skin, muscles, or other soft tissues, usually beginning in adulthood.emophilia A and hemophilia B are inherited in an X-linked recessive pattern. The genes associated with these conditions are located on the X chromosome, which is one of the two sex chromosomes.