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Creatinine is a metabolic by-product of muscle metabolism, and normally appears in urine in relatively constant quantities over a 24 hour period with normal liquid intake. Therefore, urine creatinine can be used as an indicator of urine water content or as a marker identifying a specimen as urine. Greater than normal intake of water will increase the urine water content (lowering the creatinine level) consequently diluting the amount of drug in urine. Conversely, a limited intake of water can lead to an abnormally concentrated urine specimen (as occurs with dehydration) resulting in elevated creatinine levels.
Creatinine Blood Test. A blood test for the level of creatinine in the blood is one way to check kidney function. The normal ranges are 0.8 to 1.2 mg/dl for males and 0.6-0.9 mg/dl for females.The kidney helps to maintain the creatinine levels of the blood. test for the blood urea nitrogen helps test for the proper function of the kidney. As urea is a waste product of protein metabolism built up after the breakdown of protein; the kidneys are responsible for its proper disposal. The kidneys dispose of the urea by filtering it and creating urine.