1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Many conditions can cause the development of nodules in the thyroid gland, including iodine deficiency, overgrowth of thyroid tissue, cysts, inflammation of the thyroid and the development of a goiter, according to Mayo Clinic. Thyroid cancer can also cause thyroid nodules to develop. Continue Reading.