Confidence votes 11. According to Wikipedia, the width of the Atlantic Ocean at its narrowest point is 2,848 kilometers (1,770 mi) between Brazil and Sierra Leone.
What causes PNH? It is not fully understood why people develop PNH. Inside the bone marrow, blood cells are made by stem cells (the seed cells of the marrow). PNH occurs due to a change (or mutation) in a gene in one of the stem cells in the bone marrow. This mutation happens in a gene called PIG-A and the cells made by this stem cell lack certain proteins on their surface making them âweakerâ than normal blood cells.
Paroxysmal nocturnal hemoglobinuria (PNH) definition and facts. PNH is a rare, chronic disease that causes rapid breakdown of red blood cells and can result in reddish or cola-colored urine, often seen in the early morning after urination. PNH is due to a spontaneous mutation in gene material. PNH is not inherited.