Hyponyms (each of the following is a kind of lacrimator): chlorobenzylidenemalononitrile; CS gas (a tear gas that is stronger than CN gas but wears off faster; can be deployed by grenades or cluster bombs; can cause skin burns and fatal pulmonary edema)
Freebase(0.00 / 0 votes)Rate this definition: Renin. Renin, also known as an angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system âalso known as the renin-angiotensin-aldosterone axisâthat mediates extracellular volume, and arterial vasoconstriction.
Renin is a circulating enzyme that acts on a circulating peptide, angiotensinogen. Renin cleaves the peptide at the Leu10âVal11 bond, and this reaction is the rate-determining step of the RAAS. This leads to the product angiotensin I (Ang I) which is a decapeptide.