Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
F8 and F9 Genes. Mutations in the F8 or F9 genes cause hemophilia. Mutations in the F8 gene cause hemophilia A, while hemophilia B is caused by mutations in the F9 gene. The proteins made by these genes play a critical role in the process of blood clotting.