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Carisoprodol is a skeletal muscle relaxant. It acts on the central nervous system (CNS) to relax muscles. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is used for pain and fever. Codeine is a narcotic analgesic (pain medicine) that acts on the CNS to relieve pain.
Best Answer: Acetaminophen is not an NSAID, naproxen is. They actually work quite well together. If it wasn't safe it wouldn't be recommended to take Advil (NSAID) with Vicodin (hydrocodone with acetaminophen) following wisdom tooth extractions.