A dose of 0.5 milligrams of melatonin has been taken under the tongue for six days. For seizure disorders, doses of melatonin taken by mouth were 3-10 milligrams daily for 2-4 weeks to three months. For sleep (general), doses of melatonin taken by mouth were 0.3-10 milligrams.
The degradation of the synthetic, amphoteric surfactant, cocamidopropyl betaine (CAPB) and its toxicity to the marine macroalga, Ulva lactuca, has been evaluated using several different physiological test end-points over different periods of exposure up to 120 h.ell membrane damage, estimated from measurements of ion leakage, was detected only at a concentration of 40 mg l(-1) after 48 h of exposure to CAPB but by 120 h damage was evident at all measured concentrations above 10 mg l(-1).
Isopropyl is twice as toxic as the alcohol in alcoholic beverages. It also has a greater effect on the central nervous system. Isopropyl irritates the GI tract. The lethal dose of isopropyl in humans is estimated as 8.5 oz. Drinking rubbing alcohol can cause alcohol poisoning. The symptoms of alcohol poisoning are vomiting, confusion, slow breathing (less than eight breaths per minute), seizures, low body temperature, pale or blueish skin and unconsciousness.