1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
1 It can occur due to a lack of iodine in your diet, but most people with goiters have a thyroid gland that functions normally.  Thyroid cancer is another cause of thyroid nodules, but most thyroid nodules arenât cancerous. According to Cleveland Clinic, less than 5 percent of thyroid nodules are cancerous.