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The oversight committees, particularly the HPSCI, became increasingly alarmed over the role US intelligence agencies were playing in the implementation of the administration's Central American policy. The issue of greatest concern was the CIA's support to the Contra rebels in Nicaragua.
Cholecystokinin (CCK) is the major hormone responsible for gallbladder contraction and pancreatic enzyme secretion. CCK, like other gastrointestinal hormones, is produced in discrete endocrine cells that line the mucosa of the small intestine . It is also found in the central nervous system and peripheral nerves innervating the intestine.