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Penile Discharge Fact Sheet Save this for later. Table of Contents. Penile discharge is the abnormal loss of fluid that is not urine or semen from the urethra at the tip of the penis. It is commonly the sign of a sexually transmitted disease (STD), and requires prompt and accurate diagnosis and treatment.
1 Many men with HPV never experience symptoms. 2  HPV can cause penile cancer in men.  Some men are more at risk for developing HPV-related health problems.