Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
Pakistan has four provinces: Punjab, Sindh, NWFP, and Baluchistan. Population: Today Pakistan has a population of 146.5 million people and is growing rapidly, makes it one of the top ten populous countries in the world. Most of Pakistan's population is centered in the southern province of Punjab. It is estimated that in the year 2025 the population will be about 275 million.