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Possible causes of bladder outlet obstruction might include: 1  Enlarged prostate, also known as benign prostatic hyperplasia (BPH) â this is the most common cause of bladder outlet obstruction in men. 2  Scarring of the urinary channel (urethra) or bladder neck, as a result of injury or surgery.
Overactive bladder syndrome and nervous system abnormalities, such as spinal cord injury and multiple sclerosis (disease that affects the brain and spinal cord causing weakness, coordination, balance difficulties, and other problems), can be associated with abnormal bladder contractions and urgency.