Each 100 mg BOSULIF tablet contains 103.40 mg of bosutinib monohydrate, equivalent to 100 mg of bosutinib; each 500 mg BOSULIF tablet contains 516.98 mg of bosutinib monohydrate, equivalent to 500 mg of bosutinib.
Having said that, If your dog is itching and scratching all year long, then it's most likely due to either a food allergy or an allergy to something that is present all year such as dust mites or possibly even mange. In either case, you'll probably need more help to determine the cause which you can find here.
In reality there is a wide spectrum of causes and severity of itching and scratching in dogs with skin and coat trouble. Some dogs can spend hours romping through fields, digging holes, and rolling in the grass and still have no after-effects at all.