Orange juice is the liquid extract of the fruit of the orange tree, extracted by squeezing oranges. It comes in several different varieties, including blood orange. In American English, the beverage name may be abbreviated as OJ.
Summary Summary. Listen. Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue. When the bone marrow is scarred, it cannot make enough blood cells. This leads to anemia, weakness, fatigue, and often, swelling of the liver and spleen.
Before diagnosis. About three out of 10 patients with myeloma are diagnosed at a time when they have no symptoms. The most common symptom, if you do have any, is back pain which is more severe and lasts longer than normal back pain. Myeloma can damage muscle, bone, and the kidneys. The symptoms linked to this are often described as âCRABâ because they are due to too much calcium in the blood, renal (kidney) damage, anaemia or bone damage.