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And then it went away when I started it again. It was better then a drug â¦ and no side affects! (Later, I found out that the sourse cause of the heartburn was a simple vitamine C tablet that I had also been taking.) Just one more thing. John Lee, M.D. also said that magnesium deficiency can cause leg cramps.
Leg cramps can also be a symptom of the nervous system disorder multiple sclerosis. Some people with MS experience spasticity, which can include a range of involuntary muscle spasms and twitches, as well as leg cramps. Spasticity might feel like a mild tightness or tingling in the muscles to some people or more severe cramping and pain to others.