There eventually is enlargement of the lymph nodes, liver, and spleen. Common to all leukemias are the tendency to bleed and the resultant anemia and increased susceptibility to infection. The diagnosis of leukemia requires confirmation of leukemic cells in the bone marrow by bone marrow biopsy and aspiration.
River Phoenix's autopsy showed deadly levels of cocaine and morphine (heroin shows up as morphine, as it's metabolized by the body), Valium, marijuana and ephedrine. Ephedrine is the main ingredient found in crystal meth. Official cause of death was Acute multiple drug ingestion. River Phoenix was just 23 years old.
Lance, Tyler, and Sara aren't the first victims of a thermal pool accident in Yellowstone. To date 19 people have died in the thermal regions, including seven children. The last death occurred in 1988 when a cross-country skier fell through into a hot pool. In 1981 a 24-year-old man willingly leapt to his death in Celestine Spring in a hopeless attempt to save his dog.