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Penile Discharge Fact Sheet Save this for later. Table of Contents. Penile discharge is the abnormal loss of fluid that is not urine or semen from the urethra at the tip of the penis. It is commonly the sign of a sexually transmitted disease (STD), and requires prompt and accurate diagnosis and treatment.
Trichomoniasis (female) Trichomoniasis is a sexually transmitted disease that can cause vaginal itching and discharge and pain. Vaginitis Vaginitis, an infection or inflammation of the vagina and vulva, can cause vaginal redness, itching, and more. Chlamydia (female) Chlamydia is a sexually transmitted disease sometimes causing painful urination, penile discharge and more.