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metabolism. 1. biotransformation. 2. the sum of the physical and chemical processes by which living organized substance is built up and maintained (anabolism), and by which large molecules are broken down into smaller molecules to make energy available to the organism (catabolism).
Metabolism is defined as the total of all the chemical reactions in an organism. But this definition hides what is really going on with organisms. Organisms can be considered open systems but which we mean that an organism has to take in both matter and energy and use that matter and energy to do work.