Inflammatory bowel disease (IBD) involves inflammation of the intestines and is a chronic (long-lasting) illness. The two major types of IBD are ulcerative colitis and Crohn's disease. Ulcerative colitis affects the lining of the large intestine (colon) and/or the rectum.
Definition of comb binding. : mechanical binding (as of pamphlets) in which split rings of plastic or metal are passed through slots at the gutter margin.
High-volume binding machines can be used to bind dozens to hundreds of books a day. One big determining factor in choosing a comb-binding machine is the amount of paper a machine can punch at once.