The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
Menstrual cramps and pain may be relieved with: 1  Over-the-counter painkillers, including ibuprofen or aspirin. Aspirin is not suitable for anyone under 16 years old. 2  Comforting heat, such as a hot water bottle, warm bath or shower. 3  Gentle massage of the lower part of the tummy can help relieve pain for some women.