The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
Over-the-counter pain relievers, such as Motrin (ibuprofen), Bayer aspirin, Aleve (naproxen sodium) are common drugs used to relieve everyday pain and menstrual cramps. Tylenol (acetaminophen) will help the pain, but it does not affect prostaglandins.