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There are four key causes of low creatinine: low muscle mass; liver problems; diet; pregnancy or illness; Low muscle mass. Levels of creatinine are often linked with muscle mass or the amount of muscle in the body, which can decrease with age or illness.
When the creatinine level is lower in the urine test, it indicates people may have kidney problem. As the creatinine is mostly excreted by kidney function, and the damaged kidney function cannot excrete the creatinine out, which will cause the high creatinine level in blood and low creatinine level in urine.