Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
Pakistan's latest estimated population is 207,774,520 (excluding autonomous regions Azad Kashmir and Gilgit Baltistan). This makes Pakistan the world's fifth-most-populous country, just behind Indonesia and slightly ahead of Brazil. Including Azad Kashmir, the population would be 211.819 million.