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Most of the time, no apparent cause for night leg cramps can be identified. In general, night leg cramps are likely to be related to muscle fatigue and nerve problems. The risk of having night leg cramps increases with age. Pregnant women also have a higher likelihood of having night leg cramps. Several conditions, such as kidney failure and diabetic nerve damage, are known to cause night leg cramps. But if you have one of these, you're most likely aware of it and have symptoms other than night leg cramps.
Causes of Leg spasm. This section discusses 8 medical conditions causing Leg spasm. A simple discussion of these causes with additional information is below. The following medical conditions are some of the possible causes of Leg spasm. There are likely to be other possible causes, so ask your doctor about your symptoms. 1  Muscle injury. 2  Nerve irritation. 3  Nummular eczema. 4  Nerve compression. 5  Hypocalcaemia. 6  Electrolyte abnormality. 7  Sciatica. 8  Leg injury.