Orange juice is the liquid extract of the fruit of the orange tree, extracted by squeezing oranges. It comes in several different varieties, including blood orange. In American English, the beverage name may be abbreviated as OJ.
Summary Summary. Listen. Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue. When the bone marrow is scarred, it cannot make enough blood cells. This leads to anemia, weakness, fatigue, and often, swelling of the liver and spleen.
In myelofibrosis, the bone marrow typically finds fibrosis, or scarring, of the marrow. Hyperplasia, which is an increase in the precursor cells (the cells that develop into mature red & white blood cells and platelets), is nearly always seen. This increase in precursor cells can be in one or multiple cell lines.