Examples of APPLICATION. 1  Our loan application has been approved. 2  Anyone interested in running for office must file an application by August 1st. 3  If you'd like to be considered for the job, please send us a letter of application that gives your experience and qualifications.xamples of APPLICATION. 1  Our loan application has been approved. 2  Anyone interested in running for office must file an application by August 1st. 3  If you'd like to be considered for the job, please send us a letter of application that gives your experience and qualifications.
brain reward pathways The most important reward pathway in brain is the mesolimbic dopamine system. This circuit (VTA-NAc) is a key detector of a rewarding stimulus. Under normal conditions, the circuit controls an individual's responses to natural rewards, such as food, sex, and social interactions, and is therefore an important determinant of motivation and incentive drive.
Activating the Brain Reward System. The abuse of addictive substances activates of the brain reward system. Frequently activating this system with drugs can lead to addiction. The brain reward system is naturally activated when we take part in actions that are good for us. It is part of our natural ability to adapt and survive. Whenever something activates this system, the brain assumes something necessary to survival is happening. The brain then rewards that behavior by creating feelings of pleasure.