1.) lipid peroxidation - destruction of polyunsat fats -> membrane damage and increased permeability. 2.) attacking critical proteins that affect ion pumps and transport mechanisms. 3.) fragmenting DNA - causing decreased protein synthesis. 4.) damaging mitochondria - causing the liberation of calcium into the cytosol.
Baby Aspirin May Be Best for Heart. May 8, 2007 -- Baby aspirin may be the best aspirin dose for heart health, according to a new research review. A single pill of baby aspirin contains 81 milligrams of aspirin. That's about a quarter of the 325-milligram dose in an adult aspirin pill. The new research review states that in the U.S., the most commonly prescribed aspirin dose for heart health is 81 milligrams per day. The review shows that aspirin doses greater than 81 milligrams per day haven't been proven better than baby aspirin for the heart and may increase the chances of stomach bleeding.
A 'baby' aspirin a day can help prevent heart attacks. Last updated: February 2013. Aspirin wards off heart attacks and strokes by preventing artery-blocking blood clots. But it's not for everyone. For example, the benefit against heart attacks applies mainly to men 45 and older, and the benefit against strokes is seen mainly in women 55 and older.