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Heartburn occurs when stomach acids reflux, or flow up, into the esophagus. Prilosec OTC Â® is only indicated for the treatment of frequent heartburn. If you think you may have any of the symptoms described below, please talk to your doctor or healthcare provider.
Over-the-counter antacids. Antacids can all work for occasional heartburn-although they may not be as effective for chronic heartburn.  Digestion works with a cascade of different chemicals produced when you eat, says O'Brien, which tell your stomach to produce stomach acid to help digestion. Try eating smaller meals, and don't eat two to three hours before bedtime. 2  Avoid foods that may trigger heartburn such as fried food, citrus, tomato, spices, peppermint, chocolate and fizzy drinks. 3  Cut back on alcohol and caffeine. 4  Stop smoking if you smoke. 5  Lose weight if your doctor says you're overweight.