All Direct Subsidized and Unsubsidized Loans disbursed between July 1, 2014 and June 30, 2015 carry a fixed interest rate of 4.66% for undergraduates. Graduate or professional students receiving a Direct Unsubsidized Loan disbursed between July 1, 2014 and June 30, 2015 will have a fixed interest rate of 6.21%.
There is a problem when the valve that controls what blood is good and what blood is used, no longer is strong enough to control this flow. Heart valves get damaged or simply wear out. I think you are asking what causes blood to flow in the wrong direction. My guess is that it would be a faulty heart valve.
Ischemic cardiomyopathy (IC) is a condition when your heart muscle is weakened as a result of a heart attack or coronary artery disease. In coronary artery disease, the arteries that supply blood to your heart muscle become narrowed. This can keep necessary blood from reaching portions of your heart muscle, causing damage. If you develop IC, the left ventricle in your heart will likely become enlarged, dilated, and weakened.