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There are four key causes of low creatinine: low muscle mass; liver problems; diet; pregnancy or illness; Low muscle mass. Levels of creatinine are often linked with muscle mass or the amount of muscle in the body, which can decrease with age or illness.
Because the production of creatine and creatinine is centered around protein and the muscle system, low creatinine levels usually occur in people that have little muscle tissue.This is especially the case with paralysis and other disorders that cause the muscles to atrophy.ometimes, the kidneys can regenerate and eventually your creatinine levels will go down. This is why people with kidney disease and other kidney related illnesses are encouraged to avoid eating red meat and other protein rich foods in excess. High creatinine levels can also be a sign that you are not properly hydrated.