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Most of the time, no apparent cause for night leg cramps can be identified. In general, night leg cramps are likely to be related to muscle fatigue and nerve problems. The risk of having night leg cramps increases with age. Pregnant women also have a higher likelihood of having night leg cramps. Several conditions, such as kidney failure and diabetic nerve damage, are known to cause night leg cramps. But if you have one of these, you're most likely aware of it and have symptoms other than night leg cramps.
The cause of involuntary muscle spasms should be determined. Photo Credit Jupiterimages/Photos.com/Getty Images. Involuntary muscle spasms may take the form of minor twitches or larger limb jerks. The behavior goes by a number of names, including myoclonus, muscle fasciculation and benign muscle spasms.The muscle spasms may be a mere annoyance, or they may be a sign of a serious health condition.pilepsy. Epilepsy is a cause of both major and minor involuntary muscle spasms. While most people associate epilepsy with major seizures, small muscle twitches may be the only outward symptom of the disease, according to MayoClinic.com.