The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
Answer: If self-help remedies for menstrual cramps fail to reduce your pain sufficiently after three months, you may want to consider medical treatment. Medical treatment for menstrual cramps includes the use of anti-inflammatory drugs, oral contraceptives, and stronger pain medications. Certain non-steroidal anti-inflammatory drugs (NSAIDs) decrease prostaglandin production which eases menstrual cramps.