Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
A comma splice is similar to a run-on sentence, but it uses a comma to join two clauses that have no appropriate conjunction. Fixing a run-on sentence or a comma splice can be accomplished in one of five different ways: 1  Separate the clauses into two sentences. 2  Replace the comma with a semi-colon.