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The dosage range for cephalexin (KeflexÂ®) is most often 22 to 33 mg/kg. Great Danes are big dogs as you know (weight range can be 110 to 160 pounds). Let's say your dog weighs a modest 110 pounds. They would be roughly 55 kg. 55 kg x 22 mg/kg = 1210 mg or if they used the 33 mg/kg = 1815 mg.
Side effects include diarrhea, nausea and vomiting. A typical dose is 6.25 milligrams per pound of body weight given twice a day. Keflex (Cephalexin) Keflex canine antibiotics come in gel caps or liquid. The liquid form mixes into your dog's water making it easy to give. The proper dosage is 10 to 15 milligrams per pound of a dog's weight twice a day. Dog infections of the bones, joints, lungs, skin and urinary tract frequently receive Cephalexin as a treatment. The broad-spectrum dog antibiotics prevent bacteria and fungi from reproducing.