1 Without enough saliva, the mouth is vulnerable to infections such as gum disease. 2  And some medicines can cause abnormal overgrowth of the gum tissue; this can make it difficult to keep teeth and gums clean. 3  Genetic susceptibility. 4  Some people are more prone to severe gum disease than others. Without enough saliva, the mouth is vulnerable to infections such as gum disease. 2  And some medicines can cause abnormal overgrowth of the gum tissue; this can make it difficult to keep teeth and gums clean. 3  Genetic susceptibility. 4  Some people are more prone to severe gum disease than others.
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