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S. epidermidis (a coagulase-negative staphylococcus strain) attacks the skin and can cause serious infection. Unclean plastic utensils placed in the body cause bacterial infection. S. epidermidis is resistant to antibiotics; there is no treatment.If infection is suspected, the utensil is removed and replaced.. epidermidis (a coagulase-negative staphylococcus strain) attacks the skin and can cause serious infection. Unclean plastic utensils placed in the body cause bacterial infection. S. epidermidis is resistant to antibiotics; there is no treatment. If infection is suspected, the utensil is removed and replaced.
Coagulase is a protein enzyme produced by several microorganisms that enables the conversion of fibrinogen to fibrin. In the laboratory, it is used to distinguish between different types of Staphylococcus isolates.Importantly, S. aureus is generally coagulase-positive, meaning that coagulase negativity usually excludes S. aureus. However it is now known that not all S. aureus are coagulase-positive.It is also produced by Yersinia pestis. Coagulase reacts with prothrombin in the blood. The resulting complex is called staphylothrombin, which enables the enzyme protease to convert fibrinogen, a plasma protein produced by the liver, to fibrin.his results in clotting of the blood. Coagulase is tightly bound to the surface of the bacterium S. aureus and can coat its surface with fibrin upon contact with blood. The fibrin clot may protect the bacterium from phagocytosis and isolate it from other defenses of the host.