Inflammatory bowel disease (IBD) involves inflammation of the intestines and is a chronic (long-lasting) illness. The two major types of IBD are ulcerative colitis and Crohn's disease. Ulcerative colitis affects the lining of the large intestine (colon) and/or the rectum.
Definition of comb binding. : mechanical binding (as of pamphlets) in which split rings of plastic or metal are passed through slots at the gutter margin.
Comb binding (sometimes referred to as cerlox or surelox binding) is one of many ways to bind pages together into a book. This method uses round plastic spines with 19 rings (for US Letter size) or 21 rings (for A4 size) and a hole puncher that makes rectangular holes. Comb binding is sometimes referred to as plastic comb binding or spiral comb binding.