Neither of these things are guaranteed to happen if you get the flu vaccine when you are sick, but they are possibilities. If you have just a mild illness, there is no reason to wait to get vaccinated.
Early in the day, let roast stand at room temperature at least 1 hour before cooking. Preheat oven to 375 degrees. Rub meat ... the outside and rare in the middle. Meat will be very brown ... stand at room temperature for at least one hour.
Pot roast is braised, which means the meat cooks in a few inches of liquid. You can cook it on the stove top or in the oven. When roasted in the oven, the temperature range is usually between 300Â° and 350Â°. Any higher and the meat will likely be dry and tough. Atop the stove, maintain the liquid at a slow simmer (about 180Â°) over medium-low heat.