The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
From the WebMD Archives. June 20, 2000 -- Forget Midol, aspirin, or ibuprofen. For period cramps and other menstrual symptoms, such as headaches, nausea and fatigue, women may find lasting relief from daily doses of fish oil and vitamin B-12, according to a small Danish study.