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Penile Discharge Fact Sheet Save this for later. Table of Contents. Penile discharge is the abnormal loss of fluid that is not urine or semen from the urethra at the tip of the penis. It is commonly the sign of a sexually transmitted disease (STD), and requires prompt and accurate diagnosis and treatment.
Signs and symptoms of penile cancer include: 1  a growth or sore that doesnât heal Growths or sores occur most often on the glans or foreskin, but they sometimes appear on the shaft of the penis. 2  a change in the colour of the penis The discoloured area often appears as a flat, bluish-brown growth or a reddish, velvety patch or rash.