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S. epidermidis (a coagulase-negative staphylococcus strain) attacks the skin and can cause serious infection. Unclean plastic utensils placed in the body cause bacterial infection. S. epidermidis is resistant to antibiotics; there is no treatment.If infection is suspected, the utensil is removed and replaced.. epidermidis (a coagulase-negative staphylococcus strain) attacks the skin and can cause serious infection. Unclean plastic utensils placed in the body cause bacterial infection. S. epidermidis is resistant to antibiotics; there is no treatment. If infection is suspected, the utensil is removed and replaced.
Coagulase test is used to differentiate Staphylococcus aureus (positive) from Coagulase Negative Staphylococcus (CONS). Coagulase is an enzyme produced by S. aureus that converts (soluble) fibrinogen in plasma to (insoluble) fibrin.Staphylococcus aureus produces two forms of coagulase, bound and free.lide Coagulase Test Procedure. 1  Take a clean grease free and dry glass slide. 2  Place a drop of plasma. 3  Place a drop of distilled water or saline next to the drop of plasma as a negative control. 4  Emulsify a portion of the isolated colony being tested in each drop, and make a smooth milky suspension (not clumpy).