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1 This is a common cause of SNE in the pre-school child. Children with an overactive bladder pee more than usual, often have to run to the bathroom, and are often wet during the day.  Medical conditions. Bladder infections, constipation, and diabetes can also trigger secondary nocturnal enuresis.
Nocturnal enuresis is a common problem that can be troubling for children and their families. Recent studies indicate that nocturnal enuresis is best regarded as a group of conditions with different etiologies.A genetic component is likely in many affected children.he mechanism for the benefits of imipramine in the treatment of nocturnal enuresis is not understood. One theory is that the anticholinergic effect of the drug may result in a decrease in bladder contractility that leads to increased bladder filling and improved functional bladder capacity.