Sawako Kuronuma (é»æ²¼ ç½å­ Kuronuma Sawako) is the main protagonist of the series Kimi ni Todoke.
When the intensity, duration, and/or frequency of anxiety become distressful and chronic, such that it interferes with a person's functioning, it is often referred to as pathological anxiety.Anxiety disorders represent variant forms of this pathological anxiety.hese three factors-duration, intensity, and frequency-distinguish normal, adaptive anxiety from abnormal, pathological anxiety. As such, abnormal anxiety is different from normal anxiety because it is disproportionate to the situation that elicited the anxious response.
Anxiety is complex enough that it's even possible for stress and anxiety to cause hormonal imbalances that lead to further stress and anxiety. Hormonal imbalances are an issue that can be physical and natural, or caused by stress, or both, and no matter what causes it can lead to anxiety.