2. in psychiatry, an unconscious defense mechanism in which unacceptable ideas, fears, and impulses are thrust out or kept out of consciousness. 3. gene r. enzyme repression interference, usually by the endproduct of a pathway, with synthesis of the enzymes of that pathway. gene repression the inhibition of gene transcription of an operon; in prokaryotes repressor binding to the operon is involved.
The ratio of intracellular to extracellular potassium determines neuromuscular and cardiovascular excitability, which is why serum potassium is normally regulated within a narrow range of 3.5 to 5.0 mmol/L. Dietary K+ intake is highly variable, ranging from as low as 40 mmol/day to more than 100 mmol/day.
The two ions which are most conspicuously regulated are sodium and potassium. The cell membrane is 100 times more permeable to potassium than sodium. The concentration of sodium is highest in extracellular fluid while potassium is highest in intracellular fluid.