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PU is an exaggerated pronunciation of pew, an interjection that is appropriate when you smell something foul.
Knowledge center. Pus is a protein-rich fluid called liquor puris, usually whitish-yellow, yellow, or yellow brown in color. Pus consists of a buildup of dead leukocytes (white blood cells) from the body's immune system in response to infection. It accumulates at the site of inflammation.hen the buildup is on or very near the surface of the skin it is called a pustule or pimple. An accumulation of pus in an enclosed tissue space is called an abscess.