Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
Demographics of Karachi. Trend of population growth (in millions) in Karachi. Karachi is the largest and most populous city in Pakistan. The population of Karachi is estimated to be 24 million in 2015. The population and demographic distribution in the megacity has undergone numerous changes over the past 150 years.