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The dosage range for cephalexin (KeflexÂ®) is most often 22 to 33 mg/kg. Great Danes are big dogs as you know (weight range can be 110 to 160 pounds). Let's say your dog weighs a modest 110 pounds. They would be roughly 55 kg. 55 kg x 22 mg/kg = 1210 mg or if they used the 33 mg/kg = 1815 mg.
They can bring relief to a dog with arthritis, or one whoâs just had surgery. But don't give your pooch something from your medicine cabinet. There are NSAIDs just for dogs 1  : carprofen (Novox or Rimadyl). 2  deracoxib (Deramaxx). 3  etodolac (Etogesic). 4  firocoxib (Previcox). 5  meloxicam (Metacam).