Snow White and the Seven Dwarfs production animation cel drawing Disney 1937 This is one of a series of animation roughs we have of Grumpy holding back Sneezy, Sleepy, and Bashful. The dwarfs were primarily animated in this film by Fred Moore and Bill Tytla.
Late Lyme disease â Manifestations of late Lyme disease include arthritis and neurologic conditions. In most individuals, the arthritis of late Lyme disease resolves with oral antibiotic therapy given for 28 days; intravenous antibiotics are recommended only if the arthritis does not improve with oral treatment. However, in some adults and children, arthritis persists after antibiotic therapy.
These data suggest that a single 200-mg dose of doxycycline given within 72 hours after an I. scapularis tick bite can prevent the development of Lyme disease. Doxycycline for 30 day courses has been used to treat certain cardiac, nervous system, and joint manifestations of Lyme disease. Other specific manifestations of Lyme disease are generally treated with intravenous antibiotics, most often ceftriaxone 2 gm twice daily for 14 to 30 days, and these include Lyme meningitis, neuroborreliosis, arthritis not responsive to doxycycline, and severe cardiac manifestations.