Orange juice is the liquid extract of the fruit of the orange tree, extracted by squeezing oranges. It comes in several different varieties, including blood orange. In American English, the beverage name may be abbreviated as OJ.
Summary Summary. Listen. Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue. When the bone marrow is scarred, it cannot make enough blood cells. This leads to anemia, weakness, fatigue, and often, swelling of the liver and spleen.
Make an appointment with your doctor if you have any persistent signs and symptoms that worry you. Myelofibrosis occurs when blood stem cells develop a genetic mutation. Blood stem cells have the ability to replicate and divide into the multiple specialized cells that make up your blood â red blood cells, white blood cells and platelets.