Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
A run-on sentence can be as short as four words, for instance: I drive she walks., or even I drive, she walks, because in this case, there are two subjects paired with two intransitive verbs. An imperative sentence like Run walk can be a run-on even if it only has two words. While some sources view comma splices as a form of run-on sentence, others limit the term to independent clauses that are joined without punctuation. See also