Sawako Kuronuma (é»æ²¼ ç½å­ Kuronuma Sawako) is the main protagonist of the series Kimi ni Todoke.
When the intensity, duration, and/or frequency of anxiety become distressful and chronic, such that it interferes with a person's functioning, it is often referred to as pathological anxiety.Anxiety disorders represent variant forms of this pathological anxiety.hese three factors-duration, intensity, and frequency-distinguish normal, adaptive anxiety from abnormal, pathological anxiety. As such, abnormal anxiety is different from normal anxiety because it is disproportionate to the situation that elicited the anxious response.
In some cases, a medical issue may cause an anxiety disorder. In other cases, anxiety and the medical condition may be related, but the medical condition may not have caused the anxiety disorder. Possible medical causes include: 1  Heart disease. 2  Diabetes. 3  Seizures. 4  Thyroid problems (such as hypothyroidism or hyperthyroidism). 5  Asthma.