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The dosage range for cephalexin (KeflexÂ®) is most often 22 to 33 mg/kg. Great Danes are big dogs as you know (weight range can be 110 to 160 pounds). Let's say your dog weighs a modest 110 pounds. They would be roughly 55 kg. 55 kg x 22 mg/kg = 1210 mg or if they used the 33 mg/kg = 1815 mg.
<br /><br /><br /><br /><br /> Nothing, Keflex (brand name) Cephalixin (generic) is anti-biotic and unless it's a liquid (and even then it would say on the bottle if it needs to be refrigerated) they usually don't need to be refrigerated. If you are talking about the liquid formulation, it will go bad very quickly. It will survive being left out over night at room temperature, but if a 24 hour period has passed, it needs to be thrown away as the cephalexin (which is the correct spelling) slowly becomes hydrolyzed by water, and later destroyed.