The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
NSAIDs such as CataflamÂ® (Diclofenac) may be prescribed when OTC anti-inflammatory drugs fail to adequately relieve menstrual pain. Other prescription NSAIDs often prescribed for menstrual cramps include naproxen (Naprosyn, Anaprox), iuprofen (Motrin, IBU), indomethacin (Indocin), and mefenamic acid (Ponstel). If your doctor prescribes NSAIDs, be sure to take the medicine exactly as prescribed.