Orange juice is the liquid extract of the fruit of the orange tree, extracted by squeezing oranges. It comes in several different varieties, including blood orange. In American English, the beverage name may be abbreviated as OJ.
Summary Summary. Listen. Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue. When the bone marrow is scarred, it cannot make enough blood cells. This leads to anemia, weakness, fatigue, and often, swelling of the liver and spleen.
1 The resulting fibrous scar tissue formation in the bone marrow leads to severe anemia, weakness, fatigue, an enlarged spleen and liver, and body wasting (loss of body mass or size).  Is a type of chronic leukemia and can occur on its own (primary myelofibrosis) or as a result of another bone marrow disorder. Other MPNs that can progress to myelofibrosis include polycythemia vera and essential thrombocythemia.