Neither of these things are guaranteed to happen if you get the flu vaccine when you are sick, but they are possibilities. If you have just a mild illness, there is no reason to wait to get vaccinated.
Early in the day, let roast stand at room temperature at least 1 hour before cooking. Preheat oven to 375 degrees. Rub meat ... the outside and rare in the middle. Meat will be very brown ... stand at room temperature for at least one hour.
Step 1. Preheat your oven to 325 degrees Fahrenheit for a pot roast from the round; 425 degrees for a pot roast from the chuck; and 350 degrees for a pot roast from the rib. The weight and type of roast determines the cooking time; you should cook a roast until its internal temperature is between 135 and 150 degrees F. For instance, a 2- to 3-lb. rump roast cooks for 1 Â½ to 2 hours to medium-rare doneness, the Cattlemen's Beef Board and National Cattlemen's Beef Association website advises.