Inflammatory bowel disease (IBD) involves inflammation of the intestines and is a chronic (long-lasting) illness. The two major types of IBD are ulcerative colitis and Crohn's disease. Ulcerative colitis affects the lining of the large intestine (colon) and/or the rectum.
Definition of comb binding. : mechanical binding (as of pamphlets) in which split rings of plastic or metal are passed through slots at the gutter margin.
In this method, your sheets are placed into the machine and using a lever, rectangular holes are punched into the edges of your document. Then, the plastic spine is placed into a row of stakes which, usually using the same lever that punched the holes, opens the comb binding up.