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There are four key causes of low creatinine: low muscle mass; liver problems; diet; pregnancy or illness; Low muscle mass. Levels of creatinine are often linked with muscle mass or the amount of muscle in the body, which can decrease with age or illness.
Causes of high creatinine levels. 1. Dehydration or inadequate water intake such as high fever, sweating, diuresis can cause blood concentration and reduced blood flow in the kidneys. Creatinine will increase.2. Over-tiredness, lack of rest can cause elevation of creatinine level.igh Creatinine Levels-Causes,Symptoms,Diets,Treatment. Creatinine consists of serum creatinine and urine creatinine and it often refers to serum creatinine which is an important indicator to reflect kidney functions for CKD patients. Persistently high creatinine levels are most possibly caused by kidney problems.