Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
Karachi (Urdu: Ú©Ø±Ø§ÚÛâ; Sindhi: ÚªØ±Ø§ÚÙâ; ALA-LC: KarÄcÄ«, IPA: [kÉËrÉËËtÊi]) is the capital of Sindh, and is the largest and most populous city in Pakistan, as well as the 7th largest in the world and the world's second most populous city proper. Ranked as a beta world city, the city is Pakistan's premier industrial and financial centre.