Diseases that mimic ALS. I am 35 yr Female, since December of 2010 I have had twitching in my legs,arms, feet and hands. Recently I have lost muscle in my hand (pinky joint with mild cramping) and forearm, right buttocks (large indent) and both thighs.
Jump to: navigation, search ... Deletion. Deletion is a type of mutation involving the loss of genetic material. It can be small, involving a single missing DNA base pair, or large, involving a piece of a chromosome.Narration Transcription ... s are the result of a loss of a section of the genetic material (chromosome) of the cell. If the deleted segment is small or it does not contain critical genes, the effect on the cell may be small. ~. (1) A deficiency in a chromosome resulting from the loss of a fragment through breakage.
A chromosome 4q deletion is a rare genetic condition in which there is a missing copy of part of the genetic material that makes up one of the bodyâs 46 chromosomes. Like most other chromosome disorders, this increases the risk of birth defects, developmental delay and learning difficulties.0 and co-ordination of the oral musculature â 4q33q35 deletion at 2 years. Sitting, moving, walking: gross motor skills Delay in reaching developmental milestones can be an early sign of a chromosome disorder. In children with distal 4q deletions the picture is unusually varied.