Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
With as high as 7 (Seven) million, the city of Karachi in Pakistan has the largest concentration of urban Pakhtun population in the whole world, including 50,000 registered Afghan refugees in the city.