Exploring the Southern Constellations. September 2008 : In the summer of 1865, noted American newspaperman and politician Horace Greeley penned, in an editorial, an admonishment to young civil servants in Washington DC. Greeley urged those who complained of low pay grades in the Capitol area to âGo west, young man!â.
When your muscles can't get enough oxygen during a short burst of exercise, they start to make use of a pathway called lactic acid fermentation, which generates a small three-carbon compound called lactic acid or lactate as a byproduct of glucose breakdown.
Thus, the acidification of muscle by lactic acid may alter a number of muscle proteins, including the proteins involved in Ca2+ release. The function of the Ca2+-ATPase pumps of the sarcoplasmic reticulum is also affected, which may in part explain the impaired relaxation of fatigued muscle.