ABSTRAL must be kept out of reach of children. [see Patient Counseling Information (17.1) and How Supplied/Storage and Handling (16.1)] The concomitant use of ABSTRAL with CYP3A4 inhibitors may result in an increase in fentanyl plasma concentrations, and may cause potentially fatal respiratory depression.
Renal osteodystrophy. Renal osteodystrophy or chronic kidney disease-mineral and bone disorder is a bone pathology, characterized by bone mineralization deficiency, that is a direct result of the electrolyte and endocrine derangements that accompany chronic kidney disease.
Osteomalacia in children, renal osteodystrophy, renal rickets, vitamin D deficiency Metabolism A rare condition caused by vitamin D deficiency, insufficiency or inefficiency, with interference of normal ossification in children, whose bones are poorly mineralized, accompanied by deficit of Ca2+ or PO 4 from the bone and supportive matrix; the parathyroid â PTH secretion in response to â serum Ca2+, resulting in â loss of Ca2+ and PO 4, as it is reabsorbed from bone; bone cysts may ...