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Sinus bradycardia can be the result of many things including good physical fitness, medications, and some forms of heart block. Sinus refers to the sinus node, the heart's natural pacemaker which creates the normal regular heartbeat.
In other cases, bradycardia can be a form of cardiac arrhythmia, a heart-rate abnormality. Cardiac arrhythmia can be caused by a problem in the sinus node, or it can be related to some disturbance in the passage of heartbeat signals through the A-V node and bundle of His.