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Most often, colon cancer spreads to the liver, but it can also spread to the ovaries, lungs, or brain. Colon cancer tends to spread to the liver first, because all of the blood from the colon drains to the liver before proceeding to the rest of the body.
Colon cancer or colorectal cancer often begins as a benign growth known as a colon polyp. After the disease begins to spread, it can produce signs and symptoms like. 1  blood in the stool, 2  changes in bowel patterns (like diarrhea or constipation), 3  abdominal pain,4  weight loss, or. 5  fatigue.olon cancer or colorectal cancer often begins as a benign growth known as a colon polyp. After the disease begins to spread, it can produce signs and symptoms like. 1  blood in the stool, 2  changes in bowel patterns (like diarrhea or constipation), 3  abdominal pain,