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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Urinary tract infections are far more common among women than men. But men still get them. Urinary tract infections should be taken seriously. Severe cases may cause kidney or prostate infection if left untreated. Common symptoms of urinary tract infections include. 1  burning pain during urination. 2  an urge to urinate when your bladder is nearly empty. 3  feeling like you need to urinate all the time, especially at night. 4  difficulty controlling when you urinate. 5  lower abdominal pain or back pain. 6  blood and/or pus in urine. 7  fever.