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Gadolinium contrast medium is generally very safe. Side effects or reactions are uncommon, but can occur. In patients with normal kidney function, most of the gadolinium contrast medium injected (over 90%) is passed out in the urine within 24 hours.
Among patients with severe kidney disease, the use of gadolinium-based contrast agents is linked to the development of Nephrogenic Systemic Fibrosis, or NSF. NSF was first identified in 1997 and while its cause is unknown, itâs only been reported in those with kidney disease.