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Medical Definition of anaplasma. 1  1 capitalized : a genus of parasitic, gram-negative, nonmotile bacteria of the family Anaplasmataceae that are transmitted chiefly by ticks and biting flies and infect the red blood cells of humans and animalsâsee anaplasmosis. 2  2plural anaplasmas or anaplasmata \-mÉt-É\play : any bacterium of the genus Anaplasma.
Anaplasmosis is a tickborne disease caused by the bacterium Anaplasma phagocytophilum. It was previously known as human granulocytic ehrlichiosis (HGE) and has more recently been called human granulocytic anaplasmosis (HGA). In Arkansas, Anaplasmosis is transmitted to humans by tick bites primarily from the black-legged tick (Ixodes scapularis). Of the four distinct phases in the tick life-cycle (egg, larvae, nymph, adult), nymphal and adult ticks are most frequently associated with transmission of anaplasmosis to humans.