1 paroxysmal Pertaining to or marked by paroxysm; caused by paroxysms or convulsions of nature. 2  paroxysmal Specifically In geology: Relating to or produced by a violent convulsion of nature.
Inorganic lead compounds are Group 2A - Probably carcinogenic to humans. American Conference for Governmental Industrial Hygienists (ACGIH): A3 - Confirmed animal carcinogen. Teratogenicity / Embryotoxicity: DEVELOPMENTAL HAZARD. May harm the unborn child. Known to cause: learning disabilities, effects on behaviour.
The major mechanism of lead toxicity is due to increased generation of reactive oxygen species (ROS) and interference with generation of antioxidants. Lead causes the generation of ROS like hydroperoxide, hydrogen peroxide, and singlet oxygen. ROS are stabilized by glutathione in the body.