One of the most severe side effects of Xarelto is uncontrolled bleeding. When bleeding occurs near a major organ, such as the brain, lungs or kidneys, blood flow to that organ is interrupted, causing it to lose some or all of its functionality.
In Egyptian hieroglyphs, a cartouche is an oval with a horizontal line at one end, indicating that the text enclosed is a royal name, coming into use during the beginning of the Fourth Dynasty under Pharaoh Sneferu.
Besides the name of Pepi of the Vlth Dynasty, found by Burton at Zoan, and many texts of the XIIth Dynasty, a cartouche of Apepi (one of the Hyksos kings) was found by Mariette on the arm of a statue apparently of older origin, and a sphinx also bears the name of Khian, supposed to have been an early Hyksos ruler.