ABSTRAL must be kept out of reach of children. [see Patient Counseling Information (17.1) and How Supplied/Storage and Handling (16.1)] The concomitant use of ABSTRAL with CYP3A4 inhibitors may result in an increase in fentanyl plasma concentrations, and may cause potentially fatal respiratory depression.
Renal osteodystrophy. Renal osteodystrophy or chronic kidney disease-mineral and bone disorder is a bone pathology, characterized by bone mineralization deficiency, that is a direct result of the electrolyte and endocrine derangements that accompany chronic kidney disease.
The knee is composed of three compartments, the (1) medial compartment, (2) lateral compartment, and (3) patellofemoral compartment. Osteoarthritis is a degenerative condition affecting articular cartilage. In this article, we will discuss osteoarthritis that is limited to a single compartment of the knee, known as unicompartmental arthritis. We will limit the discussion to arthritis of the medial and lateral compartments. Patellofemoral arthritis and pain syndrome are discussed here. Anatomy and Function. The knee represents the articulation, or the joint, between the femur (thigh bone), and the tibia (shin bone).