CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder.The acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.he acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Definition of devout. 1  1 : committed or devoted to religion or to religious duties or exercises a devout Catholic. 2  2 : expressing piety or religious fervor : expressing devotion a devout attitude.
characterized by irreverence or contempt for God or sacred principles or things; irreligious. 2. not devoted to holy or religious purposes; unconsecrated; secular (opposed to sacred). 3. unholy; heathen; pagan: profane rites. 4. not initiated into religious rites or mysteries, as persons.