CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder.The acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.he acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Definition of devout. 1  1 : committed or devoted to religion or to religious duties or exercises a devout Catholic. 2  2 : expressing piety or religious fervor : expressing devotion a devout attitude.
having or showing a dutiful spirit of reverence for God or an earnest wish to fulfill religious obligations. 2. characterized by a hypocritical concern with virtue or religious devotion; sanctimonious. 3. practiced or used in the name of real or pretended religious motives, or for some ostensibly good object; falsely earnest or sincere: a pious deception. 4. of or relating to religious devotion; sacred rather than secular: pious literature. 5. having or showing appropriate respect or regard for parents or others.