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Nortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.ortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
Metabolite XX The most polar metabolite derived from DEHP in the rat, this compound, like metabolite XIX, had R+=145 before and R+= 289 after trimethylsilylation. In this case, however, electron impact mass spectra of the trimethylsilyl derivative show two diagnostic fragments, at m/z = 103 and m/z = 219.