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Nortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.ortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
Often they are used in combination.I currently take 300mg/day of Lyrica (pregabalin) and 75mg/day of Elavil (amitriptilyne). Lyrica is very similar to Neurontin (gabapentin) which is an anticonvulsant. Elavil is an antidepressant. It can take time to dial in the right combination, or dose of a single med.