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Overview of Xylazine for Dogs and Cats. 1  Xylazine, commonly known as Rompun, belongs to a class of drugs known as alpha 2 adrenergic agonists and is similar to clonidine. 2  It is a sedative that provides pain relief as well as muscle relaxation to dogs.
In scientific research, xylazine is a component of the most common anesthetic, ketamine-xylazine, which is used in rats, mice, hamster, and guinea pigs. The accounts of the actions and uses of xylazine in animals were reported as early as the late 1960s and early 1970s.