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Nortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.ortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
Amitriptyline for fibromyalgia and neuropathic pain: An Assessment. Amitriptyline (once known by the brand name Elavil) is a tricyclic antidepressant that is often prescribed in low doses to treat neuropathic pain. Before there were any FDA-approved drugs to treat fibromyalgia, amitriptyline was also frequently prescribed off-label to treat FM symptoms. Although it is no longer considered a first-line treatment for fibromyalgia, a number of FM patients still find it helpful.