The resulting mRNA is a single-stranded copy of the gene, which next must be translated into a protein molecule. During translation, which is the second major step in gene expression, the mRNA is read according to the genetic code, which relates the DNA sequence to the amino acid sequence in proteins (Figure 2).
This group of drugs followed and largely superseded another group of medications with similar effects, but a different mode of action, called H2-receptor antagonists. PPIs are among the most widely sold drugs in the world, and the first one, omeprazole, is on the WHO Model List of Essential Medicines.
Prilosec Prevacid, Aciphex are proton pump inhibitors (PPI), drugs that are very effective in shutting down acid production by the stomach. Prilosec and other PPI drugs are most effective during the day, especially after meals.That is why they are taken just prior to meals. However, PPIs don't work as well at night. Ranitidine (Zantac) is a H2-receptor-blocker.Generally H2-receptor-blockers are not as effective as the PPI drugs in suppressing stomach acid production. However, Zantac and other H2-receptor blockers work particularly well at night.owever, PPIs don't work as well at night. Ranitidine (Zantac) is a H2-receptor-blocker. Generally H2-receptor-blockers are not as effective as the PPI drugs in suppressing stomach acid production.