1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Your prognosis will also be impacted by the severity of your alcohol use and the presence or absence of liver disease. Prolonged used of alcohol can cause scarring of the liver (cirrhosis). This condition is permanent and will impact your health. Cirrhosis of the liver can cause exhaustion, leg swelling, and nausea.