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Oxycodone withdrawal is expected to begin within 6 hours from the last dosage consumed by the body. The oxycodone withdrawal will also last for approximately one week or seven days. This will depend on the dosage of the drug used and as well as the length of its use in the body. The symptoms of the oxycodone withdrawal are considered to be very intense and intolerable.
1 How long does it take for oxycodone to get out of your system? 2 days: Oxycodone has a half life of about 4-5 hours so it is essentially gone within 36-48 hours of the last use of a short acting oxycodone preparation and perhaps 12 hours later after Oxycontin use.