State in writing that the LETTER OF REPRIMAND is being made a part of the employeeâs personnel file. Specify that future disciplinary action will be taken unless there is improvement and specify the measurements for satisfactory performance. Please note that in effect this is a warning as well as a reprimand.
There are thousands of single-gene diseases including achondroplasia, cystic fibrosis, hemophilia, Huntington disease, muscular dystrophy, and sickle cell disease.Single-gene diseases usually follow simple Mendelian patterns of inheritance -- autosomal dominant, an autosomal recessive, or an X-linked.Single gene diseases are as opposed to polygenic diseases which are caused by a combination of two or more genes.ingle-gene diseases usually follow simple Mendelian patterns of inheritance -- autosomal dominant, an autosomal recessive, or an X-linked. Single gene diseases are as opposed to polygenic diseases which are caused by a combination of two or more genes.
Types of single gene disorders. The occurrence of a disease caused by a single gene mutation may occur in several main patterns or modes. These are grouped according to whether the trait is sex specific (generally X-linked) or not (autosomal).As a rule, single gene disorders (also known as Mendelian traits or diseases) are relatively uncommon.ypes of single gene disorders. The occurrence of a disease caused by a single gene mutation may occur in several main patterns or modes. These are grouped according to whether the trait is sex specific (generally X-linked) or not (autosomal).