Definition. Phenylketonuria (PKU) can be defined as a rare metabolic disorder caused by a deficiency in the production of the hepatic (liver) enzyme phenylalanine hydroxylase (PAH).bbr. PKU A genetic disorder in which the body lacks the enzyme necessary to metabolize phenylalanine to tyrosine. Left untreated, the disorder can cause brain damage and progressive mental retardation as a result of the accumulation of phenylalanine and its breakdown products.
OAHU FUN FACTS. 1) Oahu is 44 miles long, 30 miles wide, 112 miles around and is the third-largest island in the Hawaiian chain of 132 islets, atolls and reefs stretching from kure atoll in the northwest to the big island of Hawaii in the southeast. 2) Honolulu is the largest city in the world.
Hawai`i: Hawaii is the largest of the habitable Hawaiian islands and covers 4,038 square miles. This island was formed by five volcanoes, two of which are still active. Kohala is on the northern side of the island. Hualalai is in the west. Mauna Kea and Mauna Loa are toward the center of the island.Kilauea is located on the eastern side of Mauna Loa. Mauna Kea, at 13,796 feet above sea level, is the highest point in the state.ohala is on the northern side of the island. Hualalai is in the west. Mauna Kea and Mauna Loa are toward the center of the island. Kilauea is located on the eastern side of Mauna Loa. Mauna Kea, at 13,796 feet above sea level, is the highest point in the state.