Supplemental Grant Application Instructions II-2 . Scenario C. Exempt Human Subjects Research If all of the proposed human subjects research meets the criteria for one or more of the exemptions from the requirements in the HHS regulations (46.101(b)) (see Part III Section 3 under Human Subjects Research
Adults with one of the above listed conditions who have not received any pneumococcal vaccine should get a dose of PCV13 first and should also continue to receive the recommended doses of PPSV23. Ask your health care provider for details.
Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. It has a high mortality rate of approximately 50% even with antimicrobial therapy. The mortality rate approaches 100% for persons with alcoholism and bacteremia.