A: The main cause of rapid population growth is when there are more births than there are deaths, which is referred to as a natural increase. Other causes of ... Full Answer >
Spanish flu (1918-1919). The influenza pandemic of 1918-1919 killed more people than the World War I, at somewhere between 20 and 40 million people. It has been cited as the most devastating epidemic in recorded world history. Known as Spanish Flu or La Grippe the influenza of 1918-1920 was a global disaster.
In the 100 years following the arrival of the Spanish to the Americas, large disease epidemics depopulated large parts of the eastern United States in the 15th century. In 1618â1619, smallpox killed 90% of the Native Americans in the area of the Massachusetts Bay.