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activation energy. activation energy, in chemistry, minimum energy needed to cause a chemical reaction. A chemical reaction between two substances occurs only when an atom, ion, or molecule of one collides with an atom, ion, or molecule of the other.
Right now, you share a quintessential problem with some chemical reactions within a cell. These chemical reactions might be a lot of fun when you're in a cell, but it takes a lot of energy to get them started. This is called the activation energy, or the energy required for a reaction to start. You can think of activation energy as that energy you needed to muster up in order to push that snowball up and over the hill in your backyard in order to maximize the size of your snowball and get it to the other side.