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Gadolinium contrast medium is generally very safe. Side effects or reactions are uncommon, but can occur. In patients with normal kidney function, most of the gadolinium contrast medium injected (over 90%) is passed out in the urine within 24 hours.
The nephron is the functional unit of the kidney. 1  Secretion of erythropoietin, which regulates red blood cell production in the bone marrow. 2  Secretion of renin, which is a key part of the reninâangiotensinâaldosterone system.  Secretion of the active form of vitamin D (calcitriol) and prostaglandins.