The resulting mRNA is a single-stranded copy of the gene, which next must be translated into a protein molecule. During translation, which is the second major step in gene expression, the mRNA is read according to the genetic code, which relates the DNA sequence to the amino acid sequence in proteins (Figure 2).
This group of drugs followed and largely superseded another group of medications with similar effects, but a different mode of action, called H2-receptor antagonists. PPIs are among the most widely sold drugs in the world, and the first one, omeprazole, is on the WHO Model List of Essential Medicines.
A: Prilosec (omeprazole) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). With the widespread use of PPIs, the long-term safety issues need to be considered.: Prilosec (omeprazole) belongs to a class of drugs called proton pump inhibitors (PPIs). PPIs decrease or block the production of stomach acid. Prilosec is used to treat the symptoms of gastroesophageal reflux disease (GERD), to promote healing of erosive esophagitis, and to treat or prevent ulcers.