You only need the English Proficient for international operations as it's an ICAO thing. Some countries, like France, check; others may not. Similar on the RRTO -- some countries, like Canada and the Bahamas don't require it, but others, like Turks & Caicos, do require it and do check it.
Apoptosis: A form of cell death in which a programmed sequence of events leads to the elimination of cells without releasing harmful substances into the surrounding area. Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unnecessary cells, and unhealthy cells.
Overview of Apoptosis. Apoptosis is the tightly controlled pattern of cell death necessary for typical growth and development in multicellular organisms. Defective apoptosis can result in abnormal development and pathogenesis. Caspases cleave target proteins at specific amino acid residues during a programmed proteolytic cascade.