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Nortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.ortriptyline is an active metabolite of Amitriptyline. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
Some gasoline additives (methyl tert-butyl ether, ethyl tert-butyl ether, and tert-amyl methyl ether) are metabolized in the liver mainly by cytochrome P450 2A6, which also metabolizes coumarin and nicotine.