1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
The University of Montana identifies three primary stages of liver disease. Fatty liver. Fatty liver is the earliest indication of the effects of alcohol on the liver. Even heavy drinkers who donât yet meet the criteria for alcoholism may have a buildup of fat in the liver. Symptoms of fatty liver include abdominal pain and swelling. Some jaundice may occur. Recovery is possible at this stage, but if left untreated, fatty liver can progress to more serious complications.