How to Respond to an Epidemic. Imagine an epidemic so virulent that it is the leading cause of death for children, teens, young adults. It takes 125,000 lives in America alone every year, not to mention causing nearly $80 billion in medical costs.
The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. This can either involve the replication of DNA in living organisms such as prokaryotes and eukaryotes, or that of DNA or RNA in viruses, such as double-stranded RNA viruses.
A consequence of the large size of eukaryotic genomes is that multiple origins of replication must be utilized in parallel to facilitate the complete duplication of the genome. within the confines of S phase (Gilbert, 2004). There are ~350 origins of replication distributed throughout the S. cerevisiae genome. In contrast, there are an estimated 40,000 â. 80,000 origins distributed throughout the much larger human genome. As in bacteria, both cis- and trans-acting factors define start sites of eukaryotic DNA replication.