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Most often, colon cancer spreads to the liver, but it can also spread to the ovaries, lungs, or brain. Colon cancer tends to spread to the liver first, because all of the blood from the colon drains to the liver before proceeding to the rest of the body.
Cancer in the colon or rectum is called colorectal cancer (or bowel cancer). Worldwide, cancer of the colon and rectum is the third leading cause of cancer in men and the fourth leading cause of cancer in women. The frequency of colorectal cancer varies around the world.