1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Alcohol, on the other hand, can single-handedly destroy your liver. Liver-related risks of alcohol consumption include fatty liver disease, which usually shows no symptoms; alcoholic hepatitis, which affects up to 35% of heavy drinkers; and alcoholic cirrhosis, the effects of which cannot be reversed.