One of the most severe side effects of Xarelto is uncontrolled bleeding. When bleeding occurs near a major organ, such as the brain, lungs or kidneys, blood flow to that organ is interrupted, causing it to lose some or all of its functionality.
In Egyptian hieroglyphs, a cartouche is an oval with a horizontal line at one end, indicating that the text enclosed is a royal name, coming into use during the beginning of the Fourth Dynasty under Pharaoh Sneferu.
The cartouche, known in ancient Egypt as the shenu, is derived from the Egyptian verb, Sheni, which means to encircle. It is very similar to the shen sign, a more circular form, and in fact the earliest use of the cartouche in which the king's name was written were circular and identical with that sign.