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What Is a Clinical Trial? A clinical trial is a research program conducted with patients to evaluate a new medical treatment, drug, or device. The purpose of clinical trials is to find new and improved methods of treating, preventing, screening for, and diagnosing different diseases.
Clinical Trial, as pertains to the review of applications submitted to the NIH. 1  A research study 1 in which one or more human subjects 2 are prospectively assigned 3 to one or more interventions 4(which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes 5.