Definition. Phenylketonuria (PKU) can be defined as a rare metabolic disorder caused by a deficiency in the production of the hepatic (liver) enzyme phenylalanine hydroxylase (PAH).bbr. PKU A genetic disorder in which the body lacks the enzyme necessary to metabolize phenylalanine to tyrosine. Left untreated, the disorder can cause brain damage and progressive mental retardation as a result of the accumulation of phenylalanine and its breakdown products.
OAHU FUN FACTS. 1) Oahu is 44 miles long, 30 miles wide, 112 miles around and is the third-largest island in the Hawaiian chain of 132 islets, atolls and reefs stretching from kure atoll in the northwest to the big island of Hawaii in the southeast. 2) Honolulu is the largest city in the world.
The area of theses islands is 6,447 square miles. The largest is the island of Hawaii, which is 4,038 square miles. Maui is 729 square miles. Oahu is 608 square miles.Kauai is 553 square miles.he size of kuleana, like the size of ahupua`a, depended on the natural fertility and abundance of the land. and this link: http://www.cr.nps.gov/history/online_boo... Hope this helps.