Specific enzymes called hydroxylases are responsible for these important reactions needed to form hydroxyproline and hydroxylysine. The hydroxylase enzymes require Vitamin C and Iron as cofactors. If a patient is Vitamin C deficient, then this reaction will not occur.n the extracellular spaces, another post-translational modification takes place as the triple helical collagen molecules (Figure 1) line up and begin to form fibrils and then fibers. This step is called crosslink formation and is promoted by another specialized enzyme called lysyl oxidase (Figure 3).
Here's the original Moody Blues as nobody knows them: Denny Laine - guitar, vocals; Clint Warwick - bass guitar; Mike Pinder - keyboards, notably Mellotron; Ray Thomas - guitar, flute, different thingamajigs; Graeme Edge - drums, dumb bits of dumb poetry.
Peter Green's Fleetwood Mac was formed by exâJohn Mayall's Bluesbreakers Green, McVie, and Fleetwood along with Elmore James enthusiast Jeremy Spencer. McVie had been a charter member of the Bluesbreakers in 1963, Fleetwood had joined in 1965, and Green had replaced Eric Clapton in 1966.