1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Abuse of alcohol may cause three types of liver damage (see also Cirrhosis of the Liver), which often develop in the following order: Accumulation of fat (fatty liver, or steatosis): This type is the least serious and can sometimes be reversed. It occurs in more than 90% of people who drink too much alcohol.