State in writing that the LETTER OF REPRIMAND is being made a part of the employeeâs personnel file. Specify that future disciplinary action will be taken unless there is improvement and specify the measurements for satisfactory performance. Please note that in effect this is a warning as well as a reprimand.
There are thousands of single-gene diseases including achondroplasia, cystic fibrosis, hemophilia, Huntington disease, muscular dystrophy, and sickle cell disease.Single-gene diseases usually follow simple Mendelian patterns of inheritance -- autosomal dominant, an autosomal recessive, or an X-linked.Single gene diseases are as opposed to polygenic diseases which are caused by a combination of two or more genes.ingle-gene diseases usually follow simple Mendelian patterns of inheritance -- autosomal dominant, an autosomal recessive, or an X-linked. Single gene diseases are as opposed to polygenic diseases which are caused by a combination of two or more genes.
Sex-linked disorders. Genetic diseases or conditions caused by a mutation on the sex chromosomes. Patterns of inheritance tend to be gender-specific. Single gene disorders. Genetic diseases or conditions caused by a mutation in a single gene or DNA sequence. Also known as Mendelian, Classical and Monogenic disorders.They are usually passed from one generation to the next. Somatic cells. Non-sex cells (not ova or sperm).Somatic or sporadic mutation.he predicted course and outcome of a disease. Recessive disorders. Genetic disease or condition caused by a mutation on both genes in a pair (homozygous). The disease or condition only arises when both parents pass on a copy of the faulty gene.