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Progesterone. Print | Email article to a friend | Last updated: January 14, 2015. Progesterone is a hormone released by the corpus luteum in the ovary. It plays important roles in the menstrual cycle and in maintaining the early stages of pregnancy. It may also be involved in the growth of certain cancers.
Understanding progesterone and what it does will help women make informed choices about their reproductive health. Progesterone is one of the progesterone steroid hormones. It is secreted by the corpus luteum, a temporary endocrine gland that the female body produces after ovulation during the second half of the menstrual cycle. What does progesterone do? Progesterone prepares the endometrium for the potential of pregnancy after ovulation. It triggers the lining to thicken to accept a fertilized egg. It also prohibits the muscle contractions in the uterus that would cause the body to reject an egg. While the body is producing high levels of progesterone, the body will not ovulate.