Speciï¬cally, the sva package contains functions. for the identifying and building surrogate variables for. high-dimensional data sets. Surrogate variables are covariates. constructed directly from high-dimensional data (like gene. expression/RNA sequencing/methylation/brain imaging data) that. can be used in subsequent analyses to adjust for unknown, unmodeled, or latent sources of noise. The sva package can be.
Princess of Wales Diana Biography. Lady Diana Frances Spencer married Prince Charles (1948â) in 1981 and became Princess of Wales. Retaining her title and her popularity after the royal couple divorced in 1996, Diana continued her charitable work. She died in a tragic car accident in 1997.
Her wedding to the Prince of Wales on 29 July 1981 was held at St Paul's Cathedral and reached a global television audience of over 750 million. While married, Diana bore the titles Princess of Wales, Duchess of Cornwall, Duchess of Rothesay and Countess of Chester.The marriage produced two sons, the princes William and Harry, who were then respectively second and third in the line of succession to the British throne.he was the fourth child and third daughter of John Spencer, 8th Earl Spencer and the Honourable Frances Shand Kydd. Following her parents' divorce, Diana grew up in Park House, which is situated on the Queen's Sandringham estate, and was educated in England and Switzerland.