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For most drugs, the window of detection in oral fluid is typically 24-48 hours. 4. How soon after use can a drug be detected in saliva? Oral fluid testing can detect drugs in the saliva roughly 30-60 minutes after ingestion.
1 Drugs can usually be detected in the saliva for only a few hours to a few days.  Hair test. Analyzing the hair for chemical traces may be the most accurate way to test for long-term drug use. Because hair grows slowly (only about 0.5 inches per month), traces of certain drugs can be detected for months.