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Fibrous Pericardium. Continuous with the central tendon of the diaphragm, the fibrous pericardium is made of tough connective tissue and is relatively non-distensible. This rigidity prevents rapid overfilling of the heart, but can have several serious clinical consequences (see cardiac tamponade).
Leave a comment Go to comments. Layers of the Heart Wall. The heart can be broken up into three major tissue layers: the endocardium, myocardium, and pericardium. Endocardium. The endocarium is the innermost, thin and smooth layer of epithelial tissue that lines the inner surface of all the heart chambers and valves.here are two layers of the pericardial sac: 1  Fibrous Pericardium: The fibrous pericardium is a strong layer which covers the heart. 2  It is made up mostly of connective tissue. 3  Its job is to protect the heart from overstretching and also anchor it in place.