1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage of liver disease.Alcoholic liver disease (ALD) is a major public health problem.The Liver Transplant Program and Center for Liver Disease estimate that it causes between 15,000 and 20,000 deaths each year in the U.S. Britainâs National Health Services estimates that 90 to 100 percent of heavy drinkers in the U.K. have ALD.o diagnose ALD, your doctor will want to test the health of your liver. At minimum, you will probably need a complete blood count (CBC), liver biopsy, and a liver function test. However, ALD is not the only disease that can cause liver damage. Ruling out other diseases may require additional blood or imaging tests.