Definition. Phenylketonuria (PKU) can be defined as a rare metabolic disorder caused by a deficiency in the production of the hepatic (liver) enzyme phenylalanine hydroxylase (PAH).bbr. PKU A genetic disorder in which the body lacks the enzyme necessary to metabolize phenylalanine to tyrosine. Left untreated, the disorder can cause brain damage and progressive mental retardation as a result of the accumulation of phenylalanine and its breakdown products.
OAHU FUN FACTS. 1) Oahu is 44 miles long, 30 miles wide, 112 miles around and is the third-largest island in the Hawaiian chain of 132 islets, atolls and reefs stretching from kure atoll in the northwest to the big island of Hawaii in the southeast. 2) Honolulu is the largest city in the world.
With an area of 4,028 square miles (10,430 km 2), it is larger than all of the other islands in the archipelago combined and is the largest island in the United States. The island of Hawaii is the third largest island in Polynesia, behind the two main islands of New Zealand.The island is often referred to as the Island of HawaiÊ»i, the Big Island, or HawaiÊ»i Island to distinguish between the island and the state.It is coterminous with HawaiÊ»i County and includes the Hilo Micropolitan Statistical Area. As of the 2010 Census the population was 185,079.ith an area of 4,028 square miles (10,430 km 2), it is larger than all of the other islands in the archipelago combined and is the largest island in the United States. The island of Hawaii is the third largest island in Polynesia, behind the two main islands of New Zealand.