The melting point (or, rarely, liquefaction point) of a solid is the temperature at which it changes state from solid to liquid at atmospheric pressure.At the melting point the solid and liquid phase exist in equilibrium.he melting point (or, rarely, liquefaction point) of a solid is the temperature at which it changes state from solid to liquid at atmospheric pressure.
Alendronate (Fosamax, Fosamax Plus D, and generic), the first bisphosphonate approved by the Food and Drug Administration for the treatment and prevention of osteoporosis, came on the market in 1995 and proved to be a moneymaker, bringing in nearly $3.2 billion in 2005.
DOSAGE AND ADMINISTRATION. 1  Treatment of osteoporosis in postmenopausal women (2.1); treatment to increase bone mass in men with osteoporosis (2.2): treatment and prevention of glucocorticoid-induced osteoporosis (2.3): a 5 mg infusion once a year given intravenously over no less than 15 minutes.