Best Answer: The biggest reason was that Britain started the Industrial Revolution earlier than other countries. Because they had newer technology, they could sell it to other countries to make money, and also use it to conquer other places.
1 Atopic dermatitis (AD) with Filaggrin (FLG) mutations is associated with an increased SC IL-1 cytokine profile; this profile is also seen in a murine homologue of filaggrin deficiency. 2  FLG mutations increase the risk for persistent dry skin, persistent eczema, and AE and non-AE at age 8 years. Loss-of-function mutations in the gene encoding FLG are linked with IV in Northern European and Japanese populations and results here demonstrate that FLG mutations are also associated with IV in a Bangladeshi population.
Although BRAF mutations are found in a wide range of cancers, there is a trend towards the occurrence of mutations in cancer types in which a substantial proportion of cases are known to harbour RAS mutations (for example, malignant melanoma, colorectal cancer and borderline ovarian cancers).ll mutations are within the kinase domain, with a single substitution (V599E) accounting for 80%. Mutated BRAF proteins have elevated kinase activity and are transforming in NIH3T3 cells. Furthermore, RAS function is not required for the growth of cancer cell lines with the V599E mutation.