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CIALIS for Use as Needed for Erectile Dysfunction. 1  The recommended starting dose of CIALIS for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity. 2  The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability.
CYP3A4 Inhibitors. CIALIS for Use as Needed â For patients taking concomitant potent inhibitors of CYP3A4, such as ketoconazole or ritonavir, the maximum recommended dose of CIALIS is 10 mg, not to exceed once every 72 hours [see WARNINGS AND PRECAUTIONS and DRUG INTERACTIONS ].