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BMS-955176 is a maturation inhibitorâthe drug prevents HIV from producing complex âpolyproteinsâ that are cut up by protease enzymes and assembled into new virus particles. If approved, BMS-955176 would be the first HIV medication to work by preventing virus assembly, maturation, and release from infected cells.
Amphotericin B (Cat. No. A4888), a polyene with high affinity for sterol binding, is one of the most potent antifungal drugs; its mechanism produces pores in the membrane surface of the yeast, resulting in leakage of the cell contents.(Odds, et al., 2003).o. A4888), a polyene with high affinity for sterol binding, is one of the most potent antifungal drugs; its mechanism produces pores in the membrane surface of the yeast, resulting in leakage of the cell contents. (Odds, et al., 2003).