ESTRING (estradiol vaginal ring) is an off-white, soft, flexible ring with a center that contains 2 mg of estradiol (an estrogen hormone). ESTRING releases estradiol into the vagina in a consistent, stable manner for 90 days.The soft, flexible ring is placed in the upper third of the vagina (by the physician or the patient). ESTRING (estradiol vaginal ring) should be removed after90 days of continuous use.If continuation of therapy is indicated, the flexible ring should be replaced.he soft, flexible ring is placed in the upper third of the vagina (by the physician or the patient). ESTRING (estradiol vaginal ring) should be removed after90 days of continuous use. If continuation of therapy is indicated, the flexible ring should be replaced.
Fertilization occurs in the Fallopian tube. If the egg is not fertilized within 24 hours after it is released, it travels down to the uterus and is expelled during the menstrual period. Continue Reading.
  The actual fertilization usually occurs in the fallopian tube.   Fertilization occurs within 12-24 hours after ovulation. Ovulation usually takes place 14 days afte â¦ r your menstruation starts.Ovulation can vary from woman to woman it can happen before day 14 and after; it doesn't always have to be on day 14.nswer by Gauravmicro. Confidence votes 9.5K. In humans internal fertilization is found and it occurs during after intercourse when male ejaculated its sperm in female vagina and when one sperm cell fuse with ovum of female then fertilization occur and which produce an egg cell.