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Cavity Structural Effect. The Cavity Structural Effect (CSE) was discovered in spring 1983 by chance by Viktor S. Grebennikov (1927-2001), entomologist and painter, when he moved his hand over multi cavernous bee nests and felt warmth emanating from them.
The chemoreceptor trigger zone (CTZ) is an area of the medulla oblongata that receives inputs from blood-borne drugs or hormones, and communicates with other structures in the vomiting center to initiate vomiting.his is because the medulla oblongata is located in the area of the brain, the most inferior portion, which does not have a robust and highly developed blood-brain barrier. Without this barrier, emetic drugs and toxins are free to interact with a receptor (biochemistry) , or multiple receptors located in the CTZ.