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the periodic discharge of blood and mucosal tissue from the uterus, occurring approximately monthly from puberty to menopause in nonpregnant women and females of other primate species. 2. the period of menstruating. Origin of menstruation. 1770-1780.
1 Menopause is the time during a woman's lifetime when menstrual periods cease. The medical definition of menopause is the time at which a woman has not had a menstrual period for 12 consecutive months.  The time preceding menopause has been referred to as the perimenopause.