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The best way to remove nail polish from clothing is the same as removing it from your nails. Nail polish remover, also known as acetone, is the key to this procedure.It's important to use nail polish remover that is pure acetone.he best way to remove nail polish from clothing is the same as removing it from your nails. Nail polish remover, also known as acetone, is the key to this procedure.
Instructions. Moisten a cotton swab in acetone nail polish remover and gently blot the entire Sharpie stain. Be sure to use acetone nail polish remover because it is the acetone chemical that removes stains.Blot the Sharpie stain with a moistened, clean cloth so that there is enough of the chemical to work on the mark but not so much that it can damage the shoe's cloth, canvas or leather surface.Remove the acetone polish remover from the shoe by wetting a clean rag with water and liberally applying it to the treated area.As the acetone is pulled from the fabric, the mark should begin to fade and disappear.pray a clean rag with cooking spray until moist and wipe the stained surface of the shoe, then blot it with a cotton swab dipped in rubbing alcohol. Rinse the cleaning solutions out of the fabric and allow the shoe(s) to dry completely.