The proteins made by varying APOE alleles handle this transport function differently. Outside the brain, APOE4 can increase the risk of atherosclerosis (i.e., hardening of the arteries) and stroke , which may explain why APOE4 is a risk factor for vascular causes of cognitive impairment and dementia .
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And a new expansion will put even more UDF products into places such as Cinergy Field and the Cincinnati Zoo, hoping for the âimpulse buysâ that retailers treasure. âThere's a whole world out there that we've never even played in,â said Jim May, vice president of the wholesale group at UDF. For one of Greater Cincinnati's most treasured names, this is its breakout year to become a regional powerhouse in gasoline and convenience-store sales.