In 1828, Dieffenbach enhanced the surgical treatment of cleft palate by introducing hard palatal mucosa elevation to allow the closure of hard palatal cleft. von Langenbeck (1859) proposed the creation of a bipedicle mucoperiosteal flap that can be mobilized medially to close the palatal cleft.
In fact, over 2 million deaths occur each year from water-related diarrhea alone. At any given time, almost half of the people in developing countries suffer from water-related diseases.â â¢ WHO World Health Report 1999. Statistical Annex. Totals of 2.3 million excluding several water-related diseases.
1 Diarrhea: Diarrhea is the most common reason for a person to lose excess amounts of water. A significant amount of water can be lost with each bowel movement. Worldwide, more than four million children die each year because of dehydration from diarrhea.  Vomiting: Vomiting can also be a cause of fluid loss.