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An artifact is one of many kinds of tangible by-products produced during the development of software. Some artifacts (e.g., use cases, class diagrams, and other Unified Modeling Language (UML) models, requirements and design documents) help describe the function, architecture, and design of software.
In software development life cycle (SDLC), artifact usually refers to things that are produced by people involved in the process. Examples would be design documents, data models, workflow diagrams, test matrices and plans, setup scripts, ... like an archaeological site, any thing that is created could be an artifact. In most software development cycles, there's usually a list of specific required artifacts that someone must produce and put on a shared drive or document repository for other people to view and share.