Abstract During embryonic development, endothelial cells differentiate from a common precursor called angioblast and acquire organ-specific properties. One of the important determinants of endothelial cell differentiation is the local environment, and especially the interaction with surrounding cells.ne of the major limitations to the study of endothelial cell heterogeneity is the fact that these cells are still difficult to isolate and culture from the microcirculation of different organs, and once in culture, they tend to lose their specialized properties.
The reason temperature is important is because wines age faster at a higher temperature, and chemically, a high temperature is bad for wine. You can tell by the color of your wine if excessive heat has damaged it. The wine will look brown.
Think of it as a tool for the short-term chilling of a wine you may want to drink in the next day or so. You never want to use your refrigerator for long-term storage of any wine. In a refrigerator, the temperature of a bottle of wine will lower 4 degrees F every ten minutes - and warms up at about the same rate.