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Risk Factors. 1  Age: renal cancer is most common in the 55-60 year age range. 2  Gender: more frequent in men than women (2:1). 3  Race: caucasian men are at somewhat higher risk than African-Amerian men (transitional cell carcinoma is twice as common among Caucasian men as among African-American men). Age: renal cancer is most common in the 55-60 year age range. 2  Gender: more frequent in men than women (2:1). 3  Race: caucasian men are at somewhat higher risk than African-Amerian men (transitional cell carcinoma is twice as common among Caucasian men as among African-American men).
In the United States, about 600,0001 people have PKD, and cystic disease is the fourth leading cause of kidney failure. Autosomal dominant PKD is the most common inherited form. Symptoms usually develop between the ages of 30 and 40, but they can begin earlier, even in childhood.