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According to my doctor, 4 hours. You can switch them up. Take acetaminophen, (Tylenol), then wait 4 hours and take Ibuprofen, wait another 4 hours and take acetaminophen and so on. :) 15 people found this useful.
Re: How soon after tylenol can I give ibuprofen. mertense: I can't remember what the timing was. DD has a fever of 103 and it came down .2 degrees with tylenol in the last 45 mintues. I know I can give her motrin/ibuprofen but I can' remember how far apart the dosing should be.