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Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).
DNA replication occurs in the synthesis or S phase of the Cell Cycle. Every chromosome is copied with high fidelity in a process that involves a large number of enzymes.ll dividing cells must go through the process of DNA replication. Since cancer cells are often rapidly dividing, this phase of the cell cycle is the target of many of the chemotherapy agents that will be described in the 'Cancer Treatments' section.