In 1828, Dieffenbach enhanced the surgical treatment of cleft palate by introducing hard palatal mucosa elevation to allow the closure of hard palatal cleft. von Langenbeck (1859) proposed the creation of a bipedicle mucoperiosteal flap that can be mobilized medially to close the palatal cleft.
In fact, over 2 million deaths occur each year from water-related diarrhea alone. At any given time, almost half of the people in developing countries suffer from water-related diseases.â â¢ WHO World Health Report 1999. Statistical Annex. Totals of 2.3 million excluding several water-related diseases.
Effects of Poor Water QualityÂ¶ Poor water quality continues to pose a major threat to human health. Diarrhoeal disease alone amounts to an estimated 4.1 % of the total DALY global burden of disease and is responsible for the deaths of 1.8 million people every year (WHO, 2004).