The proteins made by varying APOE alleles handle this transport function differently. Outside the brain, APOE4 can increase the risk of atherosclerosis (i.e., hardening of the arteries) and stroke , which may explain why APOE4 is a risk factor for vascular causes of cognitive impairment and dementia .
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A drive-thru pharmacy will be located along Corry Street, and a surface parking lot will sit in front of the building, separating it from the street. The front faÃ§ade treatments and two-level store design are departures from Krogerâs previous urban store designs elsewhere in Cincinnati.