Best Answer: The biggest reason was that Britain started the Industrial Revolution earlier than other countries. Because they had newer technology, they could sell it to other countries to make money, and also use it to conquer other places.
1 Atopic dermatitis (AD) with Filaggrin (FLG) mutations is associated with an increased SC IL-1 cytokine profile; this profile is also seen in a murine homologue of filaggrin deficiency. 2  FLG mutations increase the risk for persistent dry skin, persistent eczema, and AE and non-AE at age 8 years. Loss-of-function mutations in the gene encoding FLG are linked with IV in Northern European and Japanese populations and results here demonstrate that FLG mutations are also associated with IV in a Bangladeshi population.
DNA samples were analyzed for FLG mutations within the CAD cases of white European ethnicity and in 100 Scottish population-matched controls. The four most prevalent FLG loss-of-function mutations in this population were screened (R501X, 2282del4, R2247X, and S3247X) as previously described (Kezic et al., 2011).ilaggrin is degraded to release amino acids in the stratum corneum and FLG mutations lead to reduction in photo-absorbing amino acids, specifically urocanic acid (UCA), a chromophore for UVB that may protect against photodamage (de Fine Olivarius et al., 1996; Mildner et al., 2010; Barresi et al., 2011).