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According to my doctor, 4 hours. You can switch them up. Take acetaminophen, (Tylenol), then wait 4 hours and take Ibuprofen, wait another 4 hours and take acetaminophen and so on. :) 15 people found this useful.
Re: How soon after tylenol can I give ibuprofen. 1  mertense: I can't remember what the timing was. 2  Now, I'm no doctor, but my son just went through a whole week of 103 - 105.6 fevers. 3  I follow the label, so for tylonal it's every 4 hours, advil every 4  6. Sorry your LO is sick.  They are 2 totally separate medications.