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the periodic discharge of blood and mucosal tissue from the uterus, occurring approximately monthly from puberty to menopause in nonpregnant women and females of other primate species. 2. the period of menstruating. Origin of menstruation. 1770-1780.
Definition of menopause. 1 : the natural cessation of menstruation that usually occurs between the ages of 45 and 55; also : the period during which such cessation occurs âcalled also climacteric â compare perimenopause.