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Estimated Liver Transplant Costs. According to the United Network for Organ Sharing (UNOS)' Transplant Living Web siteOpens new window, the estimated U.S. average in 2011 of billed charges per liver transplant is $577,100.
Approximately 1,000 patients are transplanted each year for liver disease due to hepatitis C. With the cost per liver transplantation in the range of $280,000 for one year, liver transplantation for hepatitis C alone reaches a cost of nearly $300 million per year.