Parcel Select. Parcel Select is an economical choice for large or heavy packages and is the only USPS service that can be used for packages over 108 in girth. Cost is determined based on the distance, weight and dimensions of the mailpiece.
Addiction is a condition that results when a person ingests a substance (e.g., alcohol, cocaine, nicotine) or engages in an activity (e.g., gambling, sex, shopping) that can be pleasurable but the continuation of which becomes compulsive and interferes with ordinary responsibilities and concerns, such as work, relationships, or health.
Dopamine and addiction. Cocaine and amphetamines inhibit the re-uptake of dopamine. Cocaine is a dopamine transporter blocker that competitively inhibits dopamine uptake to increase the presence of dopamine. Amphetamine increases the concentration of dopamine in the synaptic gap, but by a different mechanism.