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A whole body bone scan takes around 3-4 hours, which includes two separate visits. In the first visit you will be given an injection of a radioactive isotope into a vein in your arm. There are no side effects to this injection. The isotope takes 2-3 hours to circulate in the blood and get absorbed in the bone.
The three phase bone scan detects different types of pathology in the bone. The first phase is also known as the nuclear angiogram or the flow phase. During this phase, serial scans are taken during the first 2 to 5 seconds after injection of the Technetium-99m-MDP. This phase typically shows perfusion to a lesion.