Find possible causes of numbness or tingling in hands based on specific factors. Check one or more factors on this page that apply to your symptom. Numbness or tingling. 1  Affects both hands. 2  Affects one hand.  Is intermittent.
These cells produce melanin, the substance that gives skin its color. Skin with too much melanin is called hyperpigmented skin. Skin with too little melanin is called hypopigmented skin. Pale skin areas are due to too little melanin or underactive melanocytes. Darker areas of skin (or an area that tans more easily) occurs when you have more melanin or overactive melanocytes. Bronzing of the skin may sometimes be mistaken for a suntan.
What it means to have too many platelets (thrombocytosis) When there are symptoms, they include spontaneous blood clots in the arms and legs, which if untreated can lead to heart attack and stroke. In severe cases, the patient might have to undergo a procedure called a platelet pheresis. This lowers the platelet count by removing the blood, separating out the platelets, and returning the red blood cells back to the body. With secondary thrombocytosis, the symptoms are usually related to the associated condition.