In the simplest of terms, a drug's volume of distribution is that volume of bodily fluid into which a drug dose is dissolved. Therefore, if we know the dose that was given, and we can measure the serum level (concentration), then we can calculate a volume: Volume of distribution = Dose / drug concentration.
As soon as you can make the reservation, do it, but the general consensus is at least three to six months in advance of the date. By three months out, couples have a good idea how many guests will be attending and they can plan a menu that doesnât conflict with their wedding day.
Rehearsal dinner invitations should be mailed out 4 - 6 weeks in advance of the party. The invitation should also have a RSVP so you know how many people are attending and how many dinners to order (if you are having the dinner at a restaurant that requires a head count at least seven days in advance).