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After treatment, a small number of people still have some symptoms, such as muscle aches and fatigue. The cause of these continuing symptoms, known as post-treatment Lyme disease syndrome, is unknown, and treating with more antibiotics doesn't help.Some experts believe that certain people who get Lyme disease are predisposed to develop an autoimmune response that contributes to their symptoms.More research is needed.he cause of these continuing symptoms, known as post-treatment Lyme disease syndrome, is unknown, and treating with more antibiotics doesn't help. Some experts believe that certain people who get Lyme disease are predisposed to develop an autoimmune response that contributes to their symptoms. More research is needed.
Lyme disease can produce a range of symptoms, including rash, fever, and joint pain. Most people recover fully with early antibiotic treatment. However, treatment becomes more difficult if symptoms are missed or misdiagnosed. Without treatment, people can experience more severe or prolonged symptoms. Back to top. Signs and symptoms of Lyme disease Lyme disease can affect the entire body, including the skin, joints, nervous system, and heart. Signs and symptoms of Lyme may differ depending on the type of bacterial infection and stage of the disease.