The proteins made by varying APOE alleles handle this transport function differently. Outside the brain, APOE4 can increase the risk of atherosclerosis (i.e., hardening of the arteries) and stroke , which may explain why APOE4 is a risk factor for vascular causes of cognitive impairment and dementia .
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Welcome to Panera Bread of Cincinnati, the online home of the Panera Bread franchisee in the Cincinnati metro area. From here you can browse our menu, find the bakery-cafe nearest you, learn more about us, and much more. NEW! Roasted Turkey, Apple & Cheddar Sandwich.