Best Answer: The biggest reason was that Britain started the Industrial Revolution earlier than other countries. Because they had newer technology, they could sell it to other countries to make money, and also use it to conquer other places.
1 Atopic dermatitis (AD) with Filaggrin (FLG) mutations is associated with an increased SC IL-1 cytokine profile; this profile is also seen in a murine homologue of filaggrin deficiency. 2  FLG mutations increase the risk for persistent dry skin, persistent eczema, and AE and non-AE at age 8 years. Loss-of-function mutations in the gene encoding FLG are linked with IV in Northern European and Japanese populations and results here demonstrate that FLG mutations are also associated with IV in a Bangladeshi population.
Loss-of-function mutations in the gene encoding filaggrin (FLG) are associated with skin barrier dysfunction and increased risk of atopic eczema (Palmer et al., 2006; Baurecht et al., 2007).ilaggrin is degraded to release amino acids in the stratum corneum and FLG mutations lead to reduction in photo-absorbing amino acids, specifically urocanic acid (UCA), a chromophore for UVB that may protect against photodamage (de Fine Olivarius et al., 1996; Mildner et al., 2010; Barresi et al., 2011).