How Everolimus (Afinitor) Works. Everolimus (Afinitor, made by Novartis Pharmaceuticals) is an oral compound cancer treatment, and classified as a signal transduction inhibitor â specifically, an inhibitor of the mTOR protein that controls other proteins known to trigger tumor growth.
Description. The tundra is the coldest of the biomes. It also receives low amounts of precipitation, making the tundra similar to a desert. Tundra is found in the regions just below the ice caps of the Arctic, extending across North America, to Europe, and Siberia in Asia. Much of Alaska and about half of Canada are in the tundra biome. Tundra is also found at the tops of very high mountains elsewhere in the world.
It also extends from the Arctic Ocean south to northern Kazakhstan and the borders of Mongolia and China. In total Siberia covers 5.1 million square miles (13.1 million sq km) or 77% of Russia's territory (map). History of Siberia. Siberia has a long history that dates back to prehistoric times.Evidence of some of the earliest human species has been found in southern Siberia that dates back to about 40,000 years ago.eography of Siberia. Learn Information about the Eurasian Region of Siberia. Lake Baikal, at the headwaters of the Angara River, Irkutsk, Siberia, Russia. c. 1980s. Lake Baikal is the largest freshwater lake in Asia and the deepest lake in the world.