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Keratosis pilaris results from the buildup of keratin â a hard protein that protects skin from harmful substances and infection. The keratin forms a scaly plug that blocks the opening of the hair follicle. Usually many plugs form, causing patches of rough, bumpy skin. No one knows exactly why keratin builds up. But it may occur in association with genetic diseases or with other skin conditions, such as atopic dermatitis.
Keratin buildup under toenails. Keratin is a type of protein that is found in hair, nail and the outer skin layers which makes nails strong and hard, but if a buildup of keratin occurs under the nails, it makes them discolored, brittle and deformed. Keratin buildup can also happen in the fingernails as well. Keratin is formed by the matrix of the nail. The matrix is the root of the nail that cannot be seen which is protected by the proximal fold of the nail. Keratin is a hard material that becomes soft with constant contact with moisture.