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CIALIS for Use as Needed for Erectile Dysfunction. 1  The recommended starting dose of CIALIS for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity. 2  The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability.
CIALIS for use as needed for ED. 1  Creatinine clearance 30 to 50 mL/min: A starting dose of 5 mg not more than once per day is recommended, and the maximum dose is 10 mg not more than once in every 48 hours. 2  Creatinine clearance <30 mL/min or on hemodialysis: The maximum dose is 5 mg not more than once in every 72 hours.