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Bactrim is a sulfa-based antibiotic and is not a penicillin-based medicine, according to RxList. However, a patient should discuss all allergies with a doctor to determine what drugs can and cannot be taken. Continue Reading.
The medium-spectrum antibiotics bacitracin, the Erythromycin, penicillin, and the Cephalosporins (any of a group of broad-spectrum antibiotics obtained from fungi of the genus Cephalosporium) are effective primarily against Gram-positive bacteria, although the streptomycin group is effective against some Gram-negative and Gram-positive bacteria.