It is a network of microtubules, microfilaments, and intermediate filaments that extend throughout the cytoplasm and serve as a variety of mechanical, transport, and signaling functions. (The cytoskeleton is somewhat like a highway-which can be utilized by all the molecular machinery in the cell.).
These painkillers, known as nonsteroidal anti-inflammatory drugs (NSAIDs), include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), and others. NSAIDs and anticoagulants affect the blood differently. ... Even short term NSAID treatment (two weeks ...
NSAIDs, including CELEBREX, can cause serious gastrointestinal events including bleeding, ulceration, and perforation of the stomach, small intestine or large intestine, which can be fatal. These serious adverse events can occur at any time, with or without warning symptoms, in patients treated with NSAIDs.