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Keratosis pilaris results from the buildup of keratin â a hard protein that protects skin from harmful substances and infection. The keratin forms a scaly plug that blocks the opening of the hair follicle. Usually many plugs form, causing patches of rough, bumpy skin. No one knows exactly why keratin builds up. But it may occur in association with genetic diseases or with other skin conditions, such as atopic dermatitis.
Keratin debris is formed due to infections of keratin-rich areas. Keratin debris can be caused by a fungal infection known as onychomycosis. Fungi that infect the nails can destroy small amounts of keratin, resulting in the formation of keratin debris, the Merck Manual explains.Keratin debris is formed as a result of the nails being physically broken down by the fungi.eratin debris can be caused by a fungal infection known as onychomycosis. Fungi that infect the nails can destroy small amounts of keratin, resulting in the formation of keratin debris, the Merck Manual explains.