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Risk Factors. 1  Age: renal cancer is most common in the 55-60 year age range. 2  Gender: more frequent in men than women (2:1). 3  Race: caucasian men are at somewhat higher risk than African-Amerian men (transitional cell carcinoma is twice as common among Caucasian men as among African-American men). Age: renal cancer is most common in the 55-60 year age range. 2  Gender: more frequent in men than women (2:1). 3  Race: caucasian men are at somewhat higher risk than African-Amerian men (transitional cell carcinoma is twice as common among Caucasian men as among African-American men).
The two major forms of polycystic kidney disease are distinguished by the usual age of onset and their pattern of inheritance: (1) Autosomal dominant polycystic kidney disease (ADPKD) is the most common form that usually causes symptoms between the ages of 30 and 40; but they can begin earlier, even in childhood. ADPKD can be further divided into type 1 and type 2, depending on the underlying genetic cause.