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Risk Factors. 1  Age: renal cancer is most common in the 55-60 year age range. 2  Gender: more frequent in men than women (2:1). 3  Race: caucasian men are at somewhat higher risk than African-Amerian men (transitional cell carcinoma is twice as common among Caucasian men as among African-American men). Age: renal cancer is most common in the 55-60 year age range. 2  Gender: more frequent in men than women (2:1). 3  Race: caucasian men are at somewhat higher risk than African-Amerian men (transitional cell carcinoma is twice as common among Caucasian men as among African-American men).
It is the leading cause of premature death in young diabetic patients.(between 50 and 70 years old). The disease is progressive and may cause death two or three years after the initial lesions, and is more frequent in men. Diabetic nephropathy is the most common cause of chronic kidney failure and end-stage kidney disease in the United States. People with both type 1 and type 2 diabetes are at risk. The risk is higher if blood-glucose levels are poorly controlled.