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Bactrim is a sulfa-based antibiotic and is not a penicillin-based medicine, according to RxList. However, a patient should discuss all allergies with a doctor to determine what drugs can and cannot be taken. Continue Reading.
As a type of antibiotic, Bactrim Â® (sulfamethoxazole/trimethoprim) is approved to treat the following conditions: 1  Urinary tract infections (UTIs), such as bladder infections. 2  Ear infections.3  Acute worsening of chronic bronchitis. 4  Shigellosis (a form of dysentery). 5  Traveler's diarrhea. Urinary tract infections (UTIs), such as bladder infections. 2  Ear infections. 3  Acute worsening of chronic bronchitis. 4  Shigellosis (a form of dysentery). 5  Traveler's diarrhea. 6  A certain type of pneumonia known as Pneumocystis carinii pneumonia.