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the periodic discharge of blood and mucosal tissue from the uterus, occurring approximately monthly from puberty to menopause in nonpregnant women and females of other primate species. 2. the period of menstruating. Origin of menstruation. 1770-1780.
1 Menopause is the time when a woman stops having menstrual periods.  Many women experience a variety of symptoms as a result of the hormonal changes associated with the transition to menopause.