The melting point (or, rarely, liquefaction point) of a solid is the temperature at which it changes state from solid to liquid at atmospheric pressure.At the melting point the solid and liquid phase exist in equilibrium.he melting point (or, rarely, liquefaction point) of a solid is the temperature at which it changes state from solid to liquid at atmospheric pressure.
Alendronate (Fosamax, Fosamax Plus D, and generic), the first bisphosphonate approved by the Food and Drug Administration for the treatment and prevention of osteoporosis, came on the market in 1995 and proved to be a moneymaker, bringing in nearly $3.2 billion in 2005.
For oral dosage form (effervescent tablets): For treatment of osteoporosis in men: Adultsâ70 milligrams (mg) once a week at least 30 minutes before the first food or drink of the day other than water. ChildrenâUse is not recommended. For treatment of osteoporosis in men: Adultsâ10 milligrams (mg) once a day or 70 mg once a week at least 30 minutes before the first food or drink of the day other than water.