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endocrine signaling. Signaling in which endocrine cells release hormones that act on distant target cells.
The endocrine system is a control system of ductless glands that secrete hormones within specific organs. Hormones act as messengers, and are carried by the bloodstream to different cells in the body, which interpret these messages and act on them. It seems like a far fetched idea that a small chemical can enter the bloodstream and cause an action at a distant location in the body.