References in classic literature? Without taking away her hand, she looked eagerly in his face, not quick to forebode evil, but unavoidably conscious that the state of the family had changed since her departure, and therefore anxious for an explanation. House Of Seven Gables by Hawthorne, Nathaniel View in context.
Most of this bilirubin passes into the small intestine, but a very small amount passes into your kidneys and is excreted in your urine. This bilirubin also gives urine its distinctive yellow color. This test is usually done to look for liver problems, such as hepatitis, or blockages, such as gallstones.
By this time, the cancer may have also spread beyond the pancreas. Sometimes, the first sign of jaundice is darkening of the urine from bilirubin. As bilirubin levels in the blood increase, the urine becomes brown in color. If the bile duct is blocked, bile (and bilirubin) can't get through to the bowel.