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Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. Bile acid sequestrants exchange anions such as chloride ions for bile acids.By doing so, they bind bile acids and sequester them from the enterohepatic circulation. The liver then produces more bile acids to replace those that have been lost.ile acid sequestrants are large polymeric structures, and they are not significantly absorbed from the gut into the bloodstream. Thus, bile acid sequestrants, along with any bile acids bound to the drug, are excreted via the feces after passage through the gastrointestinal tract.
Bile derivatives like bile salts, bile salt mixtures and pure substances like sodium deoxycholate and sodium taurocholate are used as selective agents mainly to inhibit gram-positive organisms, non-intestinal organisms and spore formers while permitting the growth of gram-negative enterics.ile is secreted through the bile duct into the intestine when food passes from the stomach to the duodenum. Most of the bile salts secreted into the upper region of the small intestine are absorbed along with dietary lipids at the lower end of the small intestine.