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Difference Between Physiological & Pathological Jaundice. Physiological and pathological jaundice both result in a yellow tint to the skin, whites of the eyes and mucous membranes but are caused by different conditions. Physiological Jaundice. When jaundice occurs in a healthy baby, it is considered physiological jaundice.
When bile duct cancer does cause symptoms, it is usually because a bile duct is blocked. Jaundice is yellowing of the skin and eyes. Normally, bile is made by the liver and released into the intestine. Jaundice occurs when the liver canât get rid of bile, which contains a greenish-yellow chemical called bilirubin.