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1 Serotonin is a chemical that affects mood, emotion, sleep and appetite. 2  Many antidepressants affect the amount of serotonin in the brain, and can also affect a personâs sleep.3  People beginning treatment with a new antidepressant may feel drowsier than usual for the first couple of weeks. Serotonin is a chemical that affects mood, emotion, sleep and appetite. 2  Many antidepressants affect the amount of serotonin in the brain, and can also affect a personâs sleep.
Popularly referred to as the bodyâs natural tranquilizer, GABA (gamma-aminobutyric acid) is an amino acid produced in the brain. It acts as a Neurotransmitterâa chemical that fosters communication between nerve cellsâand helps to keep stress-related nerve impulses at bay.