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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
In general, you can attempt to start running about three to four months after your injury. By this time, the bones in your ankle should be well healed, and your ROM and strength should be close to normal. You can progress your running mileage as long as your pain is minimal and your ROM and strength remain excellent. By six to nine months after your injury, you should be able to run without problems.