In the 1946 elections to the Indian constituent assembly, the Congress lost the Muslim vote to the Muslim League; it reluctantly accepted the partition of the Indian subcontinent and the formation of the state of Pakistan. After partition the Congress, as the largest party, governed India under Nehru's leadership.
ACTH is a hormone produced in the anterior pituitary gland that stimulates the adrenal glands to release cortisol, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and aldosterone.
Within the pituitary gland, ACTH is produced in a process that also generates several other hormones. A large precursor protein named proopiomelanocortin (POMC, Big Mama) is synthesized and proteolytically chopped into several fragments as depicted below.