Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
Nomenclature The terms used for various types of highways, such as freeway, expressway, motorway and autobahn, vary between countries or even regions within a country. In some places a highway is a specific type of major road that is distinct from freeway or expressway; in other places the terms may overlap.