Definition of inference for English Language Learners. : 1  the act or process of reaching a conclusion about something from known facts or evidence. : 2  a conclusion or opinion that is formed because of known facts or evidence.
Causes of Clogged Arteries. There are many substances and properties that can circulate with the blood, including cholesterol, calcium, fat, fibrin and cellular waste. When these substances accumulate on the inner walls of the arteries, they turn into plaque buildup.
However, over time deposits of fatty substances, cholesterol, cellular waste products, calcium and other substances can build up in your arteries. These plaques can severely restrict blood flow and, even more seriously, they can cause your arteries to rupture, leading to blood clots. Blood clots can then block your blood flow entirely, leading to heart attack and stroke. In fact, a build-up of plaques in your arteries, known as atherosclerosis, is the main underlying cause of heart disease.