b. PT/OT/SPL services performed, by a qualified clinician employed by a physician/NPP or physician/NPP group without a Medicare NPI should be reported to Medicare under the physicians/NPPs Medicare NPI, with an appropriate HCPCS/CPT code and the appropriate therapy modifier (GN, GO, GP).
ity.18,19 The Abl SH2 domain forms an extensive interaction interface with the C-terminal lobe of the kinase domain that is stabilized by an interlocking network of hydrogen bonds (Fig. 2).18 Due to the different relative orientation of the 2 kinase lobes in Src and Abl, the SH2 domain approaches the kinase domain much closer in Abl (Fig. 2). The SH2âC-
SRE-BP is similar to ATF6 in that it is also an ER transmembrane protein that is activated by cleavage from the membrane. SRE-BP is cleaved in a two-step process, first by site 1 protease (S1P) in the luminal loop of SRE-BP and second by site 2 protease (S2P) near the cytoplasmic end of the transmembrane domain (11).irst, deletion of various regions of the luminal domain abolished ER stress induction of GAL4-ATF6 constructs, translocation to the Golgi, and cleavage. Second, the luminal domain was necessary and sufficient for translocation of ATF6 from the ER to the Golgi.