Definition of inference for English Language Learners. : 1  the act or process of reaching a conclusion about something from known facts or evidence. : 2  a conclusion or opinion that is formed because of known facts or evidence.
Another risk factor for clogged arteries is having a high blood pressure. When you have high blood pressure, there is a greater chance in speeding up the process of arterial plaque buildup. This also expedites the hardening of the clogged arteries.
However, over time deposits of fatty substances, cholesterol, cellular waste products, calcium and other substances can build up in your arteries. These plaques can severely restrict blood flow and, even more seriously, they can cause your arteries to rupture, leading to blood clots. Blood clots can then block your blood flow entirely, leading to heart attack and stroke. In fact, a build-up of plaques in your arteries, known as atherosclerosis, is the main underlying cause of heart disease.