Humans cannot synthesize astaxanthin in the body, nor does it appear to act as a pro-vitamin for Vitamin A (retinol) in mammals under normal conditions although it appears that in states of Vitamin A deficiency astaxanthin (in rats) can be forced into a provitamin role.
Annual Running Cost (Â£) = Cost per mile x Average mileage /100. The Renault Clio takes about 40 litres to fill up and travels 400 miles on a full tank, giving it a respectable MPG of 45. This equates to around 10.5p/mile assuming that the Price of Petrol is around 105p per litlre. For a Renault Clio.
If it's too low, you can usually negotiate for a higher limit, but doing so will increase the cost of the lease. If you are a high-mileage driver -- 18,000 miles per year or more -- you may be better off buying the car instead of leasing. (Be warned: One unscrupulous dealer trick is to offer a low-cost lease with an absurdly low mileage limit.).