Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
Section 247 Town and Country Planning Act 1990 - stopping up orders. If the order is made under the Town and Country Planning Act 1990, it will generally relate to an area of highway which is to be built upon or affected by development in some form.topping up orders are often made because the public highway is no longer necessary or to allow development to take place. The phrase 'public highway' can include roads, streets, footpaths, some public car parks, grass verges and footways. Not all roads, streets or footpaths are public highways.