Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
Interstate Highway System. 1. a network of U.S. highways connecting the 48 contiguous states and most of the cities with populations above 50,000, begun in the 1950s and estimated to carry about a fifth of the nation's traffic. Examples from the Web for Interstate Highway System Expand. Contemporary Examples. And in the 20th century, the federal government built the Interstate Highway System, without which, say, Walmart, could not exist. Eisenhower and Congress worked to enact the Interstate Highway System.