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Treat fabraea leaf spot with fungicides and cultural controls. Spray the pear tree with a fungicide in early and middle summer to control the presence of fungal spores on the tree.
You spray the tree while it is dormant-late March. You should be good until July-August. The cost of the sprayer and spray is about $50. The spray should be enough for 5 years. Unless, the bees decide to make the tree their home, I'd say don't kill them, they help with the pollination.