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This type of pain is usually localized, affecting just a few muscles or a small part of your body. Systemic muscle pain â pain throughout your whole body â is more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: Chronic exertional compartment syndrome. Chronic fatigue syndrome.
De Quervain's tendinosis occurs when the tendons around the base of the thumb are irritated or constricted. The word tendinosis refers to a swelling of the tendons. Swelling of the tendons, and the tendon sheath, can cause pain and tenderness along the thumb side of the wrist. This is particularly noticeable when forming a fist, grasping or gripping something, or when turning the wrist. Anatomy.