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Another reaction is the prompt for saliva to be produced, which allows us to easily chew and digest our food. For people with long-term CPAP use, the theory is that loss of taste and smell might actually be due to becoming desensitized from the smell of the CPAP machine. This can then cause the loss of taste.
Side effects of CPAP use are usually minor and may include: 1  Feelings of confinement from the face mask. 2  Sore or dry mouth. 3  Nasal congestion, runny nose, sinusitis, or nosebleeds. 4  Irritation and sores over the bridge of the nose. 5  Stomach bloating and discomfort. 6  Discomfort in chest muscles.