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Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. Bile acid sequestrants exchange anions such as chloride ions for bile acids.By doing so, they bind bile acids and sequester them from the enterohepatic circulation. The liver then produces more bile acids to replace those that have been lost.ile acid sequestrants are large polymeric structures, and they are not significantly absorbed from the gut into the bloodstream. Thus, bile acid sequestrants, along with any bile acids bound to the drug, are excreted via the feces after passage through the gastrointestinal tract.
Medical Definition. The liver creates a detergent-like chemical, stored in the gallbladder, that absorbs certain parts of food and prevent others from absorption as well. Bile salts are created from bile acids conjugated to glycine or taurine and secreted in the bile from the liver.he main purpose is to breakdown fat globules for easier digestion and absorption in the intestine by emulsifying them. Bile salts is mixture of sodium salts of the bile acid and cholic and chenodeoxycholic acids produced in the liver as a compound of cholesterol.