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AS, AD, and AU are the medical abbreviations for left ear, right ear, and both ears.
OD is an abbreviation for the Latin oculus dexter, meaning right eye. OS is an abbreviation for the Latin oculus sinister, meaning left eye. The first number after the determination of which eye is the sphere. A negative number indicates myopia. A positive number indicates hyperopia. The second number in this prescription is the cylinder (astigmatism), and the third number is the axis of the cylinder component.