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Difference Between Physiological & Pathological Jaundice. Physiological and pathological jaundice both result in a yellow tint to the skin, whites of the eyes and mucous membranes but are caused by different conditions. Physiological Jaundice. When jaundice occurs in a healthy baby, it is considered physiological jaundice.
Physiologic Jaundice. Physiologic Jaundice is the most common and normal type of jaundice in babies. It can affect up to 60% of full term babie s in the first week of life, and it is caused by elevated bilirubin levels. Bilirubin is a substance created by the normal breakdown of red blood cells.It is processed and removed by the liver. Jaundice will develop when a babyâs liver is not efficient enough to remove the bilirubin from the bloodstream.ilirubin is a substance created by the normal breakdown of red blood cells. It is processed and removed by the liver. Jaundice will develop when a babyâs liver is not efficient enough to remove the bilirubin from the bloodstream.