Giant axonal neuropathy is caused by mutations in the GAN gene, which provides instructions for making a protein called gigaxonin. Some GAN gene mutations change the shape of the protein, affecting how it binds to other proteins to form a functional complex.iant axonal neuropathy generally appears in infancy or early childhood. It progresses slowly as neuronal injury becomes more severe. Signs of giant axonal neuropathy usually begin in the peripheral nervous system, which governs movement and sensation in the arms, legs, and other parts of the body.
The Handmaid's Tale will enter production later this year, and premiere on Hulu in 2017. I am thrilled that MGM and Hulu are developing The Handmaid's Tale as a series, and extra thrilled that the very talented Elizabeth Moss will be playing the central character, Atwood said.
The Handmaid's Tale is a 1985 dystopian novel by Canadian author Margaret Atwood. Set in a near-future New England, in a totalitarian, Christian theonomy that has overthrown the United States government, the novel explores themes of women in subjugation and the various means by which they gain individualism and independence.