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This type of pain is usually localized, affecting just a few muscles or a small part of your body. Systemic muscle pain â pain throughout your whole body â is more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: Chronic exertional compartment syndrome. Chronic fatigue syndrome.
Bruise or contusion Bruises, or contusions, cause skin discoloration, swelling and tenderness. Muscle strain Muscle strain occurs when muscles are stressed, overworked, or injured due to physical activity or labor.