HOUSTONâJustin Friendâs parents have doctoral degrees and have worked as university lecturers and researchers. So Mr. Friend might have been expected to head for a university after graduating from high school in Bryan, Texas, five years ago. Instead, he attended Texas State Technical College in Waco, and received a two-year degree in welding.
A flurry of emergent research has linked mitochondrial dysfunction to the pathogenesis of Parkinson's disease. Mitochondrial dysfunction results in impaired ATP generation, loss of cellular repair mechanisms, and cellular inefficiency.
1 Mitochondrial disease is a chronic, genetic disorder that occurs when the mitochondria of the cell fail to produce enough energy for cell or organ function. 2  The incidence is about 1:4000 individuals in the US.he severity of mitochondrial disease symptoms is different from person to person. The most common symptoms are: 1  Poor growth. 2  Loss of muscle coordination, muscle weakness. 3  Neurological problems, seizures.