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One common cause of muscle aches and pain is fibromyalgia, a condition that causes tenderness in your muscles and surrounding soft tissue, sleep difficulties, fatigue, and headaches.
1 Tenderness in the affected muscle or joint. 2  Pain in the affected muscle or joint. 3  A throbbing (pulsating) sensation in the affected area. 4  Tingling sensation in the affected area (especially the hand or arm) 5  Loss of sensation.  Loss of strength.