In summary, we have shown the inhibitory effects of Bcl-2 family on the ceramide-mediated apoptotic pathway in glioma cells. Bcl-2 is considered to act not only downstream of ceramide to inhibit cytochrome c release followed by caspase activation, but also upstream of or at SMase to prevent ceramide generation.igure 3 Effects of Bcl-2 or Bax overexpression on ceramide formation and neutral sphingomyelinase activation in etoposide-treated C6 cells. C6/Neo (), C6/Bcl-2 (), and C6/Bax () cells were treated with 40 M etoposide for indicated periods.
Hawaii, which has the highest-paid waiters and waitresses in the country (mean wage: $13.91/hour) has a minimum wage of $7.00 for tipped employees.
  A waitress usually makes around $2.50 to 3.50 an hour from the company itself. That's because waiters main income comes from tips. If you aren't making at least like 6.7 â¦ 5 an hour (tips included/ whatever minimum wage is now for Missouri) then I believe the company is to pay you more.he employer is given what they call a tip credit. In order to pay a waitress the 2.63 per hour, the wai â¦ tress must make up the difference between 2.63 and the state minimum of 8.00. Which would be 5.37 per hour in tips.