In addition, thiazolidinediones have several other potential side effects, which make them less appealing as initial or second step therapy. (See 'Cardiovascular effects' below and 'Safety' below.). The pharmacology and use of thiazolidinediones will be reviewed here.
Alcohol impairs brain areas such as the cerebellumâthe control site for your balance and coordinationâand your cerebral cortex, which is responsible for thinking, memory, and learning, says Kimberly S. Walitzer, Ph.D., deputy director of the University at Buffaloâs Research Institute on Addictions.
How can alcohol damage the brain? Heavy alcohol consumption over a long period of time can lead to brain damage. People who drink heavily over a long period of time are more likely to have a reduced volume of the brain's white matter, which helps to transmit signals between different brain regions.