In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
Aug. 15, 2006 -- Gout ups a man's risk of heart attack, even if he doesn't drink, isn't obese, and doesn't have diabetes. The finding comes from 6.5 years of data collected on a nationwide sample of nearly 13,000 U.S. men. It helps solve a medical mystery.