Calf vein thrombosis is diagnosed in two clinical scenarios: 1  In search for a deep vein thrombus due to clinical suspicion in vascular laboratories with protocols that mandate search for clots in the calf and not only the thigh.he diagnosis of calf vein thrombosis is established with duplex ultrasound utilizing the same principles that are used in proximal deep vein thrombi. A thrombus is diagnosed if there is lack of compression and/or lack of augmentation of flow.
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