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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Visible Blood: Indicates the presence of blood in the urine specimen. The presence of blood in the urine sample may adversely impact the testing process and, in addition, constitutes a biohazard for laboratory employees. Collection of clean catch urine specimens during menstruation should be attempted.