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3 Structural gene clusters are coordinately controlled. 1  An operon is a unit of bacterial gene expression and regulation, including structural genes and control elements in DNA recognized by regulator gene product(s).acterial structural genes are often organized into clusters that include genes coding for proteins whose functions are related.
Figure 1: The lac operon in E.coli. Three lactose metabolism genes (lacZ, lacY, and lacA) are organized together in a cluster called the lac operon. The coordinated transcription and translation of the lac operon structural genes is supported by a shared promoter, operator, and terminator. A lac regulator gene with its promoter is found just outside the lac operon. Â© 2013 Nature Education Adapted from Pierce, Benjamin. Genetics: A Conceptual Approach, 2nd ed.