Amikacin was patented in 1971 and came into commercial use in 1976. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is 13.80 to 130.50 USD for a month.
olfactory. pertaining to smell. olfactory nerve the first cranial nerve; it is purely sensory and is concerned with the sense of smell. The nerve cell bodies are situated in the olfactory area of the mucous membrane of the nose.lfactory system. includes the olfactory part of the nasal mucosa, the olfactory nerves and the olfactory bulbs of the cerebrum. olfactory tract. a band of white nerve fibers visible on the ventral surface of the brain running caudally from the olfactory bulbs.
The olfactory bulb is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell. It sends olfactory information to be further processed in the amygdala, the orbitofrontal cortex and the hippocampus where it plays a role in emotion, memory and learning. The bulb is divided into two distinct structures: the main olfactory bulb and the accessory olfactory bulb. The main olfactory bulb connects to the amygdala via the piriform cortex of the primary olfactory cortex and directly projects from the main olfactory bulb to specific amygdala areas. The accessory olfactory bulb resides on the dorsal-posterior region of the main olfactory bulb and forms a parallel pathway.