Biography and career. Satterfield was born Louis Edward in Shaw, Mississippi, a city in Bolivar and Sunflower counties, Mississippi, in the Mississippi Delta region, on April 3, 1937.
Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract.When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.hen calcium binds to the TN-C, this induces a conformational change in the regulatory complex such that troponin-I (TN-I) exposes a site on the actin molecule that is able to bind to the myosin ATPase located on the myosin head.
A quick review of excitation-contraction coupling in skeletal muscle: The sarcoplasmic concentration of calcium in skeletal muscle is kept very low by the action of Ca-ATPases which remove the calcium and sequester it in the sarcoplasmic reticulum. When an action potential depolarizes the muscle cell membrane, it also travels into the body of the cell via the t-tubules.