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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Early detection of bacteria in urinalysis requires a collection of a urine sample. The sample should be a clean catch specimen to eliminate the possibility of bacteria residing on the skin contaminating the specimen. A clean catch specimen is obtained by washing the genital area and beginning to urinate.