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There are several different types of globin chains, named alpha, beta, delta, and gamma. Normal hemoglobin types include: 1  Hemoglobin A (Hb A): makes up about 95%-98% of hemoglobin found in adults; it contains two alpha (Î±) chains and two beta (Î²) protein chains.
In general, there are numerous ways to detect forms and variants of hemoglobin, including enzymatic, cationic chromatography, afï¬nity chromatography, and immunochemical methods [10]. However, the commonly used tests for detection of hemoglobin in fecal samples include the guaiac-based FOBT (gFOBT), and the fecal immunochemical test (FIT). The gFOBT utilizes guaiac and hydrogen peroxide to detect the heme component of hemoglobin. Although it is cheaper [11],