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All parts are affected in some manner, since it is a disease that affects the brain. It is a disease of nervous system. So it affects the parts wherever nerves are and nerves are about everywhere in body. Huntington's is a neurological disease that affects the brain.
Huntington's disease is an inherited disorder that causes progressive damage to your brain cells. This leads to problems in controlling your movements and changes in your personality and mental ability.he physical symptoms of Huntingtonâs disease include the following. 1  Involuntary fidgeting movements of your limbs, face and body are called chorea. 2  These movements may start in your hands and feet and gradually spread to the rest of your body. 3  Difficulty in co-ordinating your movements may develop.