1 This is typically due to: irregular pregnancy signs, heightened pregnancy signs, and the fact that tâ¦. 2  Pregnancy Symptoms with Twins You are pregnant. 3  It has just been a couple of weeks, but you are having some interesting symptoms.
Enlargement of beta cells of the pancreas that produce insulin (nesidioblastosis) may result in excessive insulin release, causing hypoglycemia. 1  Hormone deficiencies. 2  Certain disorders of the adrenal glands and the pituitary gland can result in a deficiency of key hormones that regulate glucose production.
So the pancreas just puts out more insulin. Cells become insulin resistant because they are trying to protect themselves from the toxic effects of high insulin. They down-regulate their receptor activity and number of receptors so that they don't have to be subjected to all that stimuli all the time.