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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Evidence Collection Handbook - BLOOD AND OTHER BODY FLUIDS. 1  Evidence in this category includes blood of human or animal origin, semen, saliva, urine, and skin tissue submitted for the purpose of identification and characterization according to genetic factors such as isoenzymes and DNA profiles.