1 Exotoxins are proteins released by both Gram-positive and Gram-negative bacteria. 2  all major Gram-positives produce exotoxin. 3  except Listeria monocytogenes (produces endotoxin). 4  exotoxins are not heat stable.
Endocarditis (EN-do-kar-DI-tis) is an infection of the inner lining of the heart chambers and valves. This lining is called the endocardium (en-do-KAR-de-um). The condition also is called infective endocarditis (IE). The term endocarditis also is used to describe an inflammation of the endocardium due to other conditions. This article only discusses endocarditis related to infection. IE occurs if bacteria, fungi, or other germs invade your bloodstream and attach to abnormal areas of your heart.
Endocarditis is a disease characterized by inflammation or infection of the inner surface of the heart (the endocardium). This article will focus on endocarditis that is the result of infection (infective endocarditis). Endocarditis commonly affects heart valves, but may also involve nonvalvular areas or mechanical devices that are implanted in the heart, such as artificial heart valves, pacemakers, or implantable defibrillators.