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There are several different types of globin chains, named alpha, beta, delta, and gamma. Normal hemoglobin types include: 1  Hemoglobin A (Hb A): makes up about 95%-98% of hemoglobin found in adults; it contains two alpha (Î±) chains and two beta (Î²) protein chains.
Hemoglobin (Hgb) is comprised of many different types, the most common being A 1, A 2, F, S, and C. Hgb A 1 is the major component of hemoglobin in the normal red blood cell. Hgb A 2 is a minor component of normal hemoglobin, comprising approximately 2-3% of the total. Hgb F is the major hemoglobin component in the fetus, but usually exists only in minimal quantities in the normal adult. Levels of Hgb F greater than 2% in patients over three years of age are considered abnormal.