adjective. 1  regardless of sin reparar en; buy it regardless of the cost cÃ³mpralo, cueste lo que cueste; they shot them all regardless of rank los fusilaron a todos sin miramientos a su graduaciÃ³n; we did it regardless of the consequences lo hicimos sin tener en cuenta las consecuencias.
Yes, their are two active ingredients in tramacet. Tramadol hydrochloride and paracetamol. Tramadol hydrochloride is an opioid and is closely related to morphine. It is actually synthetic form of morphine.
Its analgesic effects are only partially reversed by naloxone, hence indicating that its opioid action is unlikely the sole factor; tramadol's analgesic effects are also partially reversed by Î±2 adrenergic receptor antagonists like yohimbine and the 5-HT3 receptor antagonist, ondansetron.