If you look at a big metabolic chart, like a detailed road map, youâll see that PFK is the first âcommittedâ enzyme for glycolysis. It is tempting to think that hexokinase/glucokinase should be the one, but the product, Glucose 6-phosphate has man...
The first settlement in the region of present-day Cairo was al-Fustat, founded in A. D. 641 as a military encampment by the Arabic commander 'Amr ibn al-'As. Under the dynasties that ruled Egypt over the following centuries, the town grew into a major port city. In A. D. 969 Jawhar, the leader of an Islamic sect called the Fatimids, founded a new city near al-Fustat, initially naming it al-Mansuriyah (its name was later changed to al-Qahirah, or Cairo). When the Fatimids became the rulers of Egypt, founding a dynasty that lasted for two centuries, Cairo became their capital. When Saladin, a Sunni Muslim, defeated the Crusaders and founded the Ayyubid dynasty in the twelfth century, he retained Cairo as his capital, and it became the center of a vast empire.
Cairo itself was besieged by a British and Ottoman force culminating with the French surrender on 22 June 1801. The British vacated Egypt two years later, leaving the Ottomans, the Albanians, and the long-weakened Mamluks jostling for control of the country.