1 The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. 2  Infants younger than 6 months of ageâUse and dose must be determined by your doctor. 3  For menstrual cramps: 4  Adultsâ400 milligrams (mg) every four hours, as needed.
Diclofenac and misoprostol combination is used to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis) in patients who may develop stomach ulcers from taking nonsteroidal anti-inflammatory drugs (NSAIDs).
Diclofenac is available as a generic drug in a number of formulations, including diclofenac diethylamine, which is applied topically. Over-the-counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.s long-term use of diclofenac and similar NSAIDs predisposes for peptic ulcer, many patients at risk for this complication are prescribed Arthrotec-a combination of diclofenac and misoprostol, a synthetic prostaglandin (PGE1) analogue, to protect the stomach lining.