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All blood donations are processed and available for use usually within 24 hours. Whole blood is processed into components (red blood cells, platelets, plasma). After processing, the red blood cells can be stored for 42 days.
It may take up to two weeks to replace the lost red blood cells. Whole blood can be donated once every eight weeks (56 days). Two units of red blood cells can be donated at one time, using a process known as red cell apheresis. This type of donation can be made every 16 weeks.