1 The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. 2  Infants younger than 6 months of ageâUse and dose must be determined by your doctor. 3  For menstrual cramps: 4  Adultsâ400 milligrams (mg) every four hours, as needed.
Diclofenac and misoprostol combination is used to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis) in patients who may develop stomach ulcers from taking nonsteroidal anti-inflammatory drugs (NSAIDs).
Diclofenac/misoprostol is contraindicated in pregnant women because the misoprostol component can cause abortion. Misoprostol has been shown to cause the uterus to tear in pregnant women if it is used to induce labor or to cause an abortion after the first trimester of pregnancy.