Biography and career. Satterfield was born Louis Edward in Shaw, Mississippi, a city in Bolivar and Sunflower counties, Mississippi, in the Mississippi Delta region, on April 3, 1937.
Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract.When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.hen calcium binds to the TN-C, this induces a conformational change in the regulatory complex such that troponin-I (TN-I) exposes a site on the actin molecule that is able to bind to the myosin ATPase located on the myosin head.
How does excitation-contraction coupling in a cardiac muscle cell differ from that in a skeletal and smooth muscle fiber. Cardiac--depolarization due to influx of calcium ions through voltage gated channels (L type calcium channels which are modified versions of the DHP receptors in skeletal muscle). Cardiac--instead of being open directly by voltage as in skeletal muscle, cardiac are opened by binding of trigger calcium in cytosol.