In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
The more severe type of heart attack is called an ST-segment-elevation myocardial infarction, or STEMI. In a STEMI, the coronary artery is completely blocked by a blood clot, so all of the heart muscle that usually receives blood from the affected artery will begin to die.