1 We all want bright, white smiles â they can take years off your appearance and boost your confidence. 2  And while bleaching your teeth is an effective (and generally safe) whitening step, it also helps to avoid foods that stain teeth in the first place.
Ramelteon (ra mel' tee on) is a synthetic melatonin receptor agonist with affinity for both the melatonin type 1 and type 2 receptors (MT1 and MT2). These receptors are believed to be involved in the maintenance of the circadian rhythm that regulates the normal sleep-wake cycle.
Healthy young and middle-aged adults usually secrete about 5 to 25 micrograms of melatonin each night - at least 80 times less than is in the commonly sold 2 milligram (mg) tablet or capsule. Ramelteon and melatonin are selective melatonin agonists. Both have high affinity for the MT1 melatonin receptors in the brain's suprachiasmatic nuclei (SCN). The SCN regulates the 24-hour sleep-wake cycle in humans. Ramelteon and melatonin also stimulate MT2 receptors in the retina and MT3 receptors in the gut.