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All parts are affected in some manner, since it is a disease that affects the brain. It is a disease of nervous system. So it affects the parts wherever nerves are and nerves are about everywhere in body. Huntington's is a neurological disease that affects the brain.
Huntingtonâs disease is a neurological (nervous system) condition caused by the inheritance of an altered gene. Symptoms often donât appear until the person is in their thirties or forties and not all people with Huntington's disease experience the same symptoms. Behavioural problems are thought to be caused by a combination of events, including damage to the brain as the disease progresses and the understandable frustration and depression that people feel when challenged by chronic illness.