In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
One of the hearts problems is heart attack, which occurs when the heart does not get enough oxygenated blood due to certain blockage in the coronary arteries. The main symptoms of a heart attack are chest pain or angina, breathing problems and faintness. Blocked arteries are a major cause of heart attacks.