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All parts are affected in some manner, since it is a disease that affects the brain. It is a disease of nervous system. So it affects the parts wherever nerves are and nerves are about everywhere in body. Huntington's is a neurological disease that affects the brain.
Huntington's disease affects an estimated 3 to 7 per 100,000 people of European ancestry. The condition appears to be less common in other populations, such as African Americans. In the United States alone, about 30,000 people have Huntington's disease; about 1 in every 10,000 people is thought to have the condition.