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Patients with cardiomyopathy, a stiffening and thickening of the heart muscle that weakens it, may develop an enlarged heart as it labors to pump an adequate supply of blood to the body. Coronary artery disease, in which plaque in the arteries interferes with the flow of blood, can cause the heart to enlarge.
Enlarged Heart Causes, Symptoms, and Treatment. An enlarged heart is also referred to as cardiomegaly. This condition is a sign of an overworked heart. This article gives information regarding the possible causes, symptoms, and the treatment options that can help one control the adverse effects of an enlarged heart. Advertisement. Our heart is divided into 2 sides-the left side and the right side.