Medicines may be needed when symptoms of sinusitis are severe or do not improve. The goals of treatment with medicine are to: Treat the infection, which is usually caused by bacteria if your symptoms have lasted more than 7 to 10 days. Relieve pressure and pain caused by poor sinus drainage.
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Accepted 2 October 2010, Available online 10 October 2010. Nitrous oxide (N2O)-induced antinociception is thought to result from nitric oxide (NO)-dependent neuronal release of endogenous opioid peptides in the central nervous system.