Doctors administer sclerotherapy by injecting a sclerant (a sterile chemical which irritates the vein lining) into your vein causing it to close and eventually be reabsorbed into the body. To compensate for the loss of the vein, blood circulation is re-routed through healthy veins.
Abstract. 1  Metaplastic breast cancer (MBC) is a rare subtype of invasive breast cancer that tends to have an aggressive clinical presentation as well as a variety of distinct histologic designations. Few systemic treatment options are available for MBC, as it has consistently shown a suboptimal response to standard chemotherapy regimens.
Metaplasia. Definition: Metaplasia is the reversible replacement of one differentiated cell type with another differentiated cell type. Metaplasia causes precursor cells to change their cell fate, and do not change existing differentiated cells.he most common epithelial metaplasia is columnar to squamous (squamous metaplasia), as occurs in the respiratory tract in response to chronic irritation.