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Pathophysiology. The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen.
Digestive health centre. Colonic irrigation, or colonic hydrotherapy, is where waste material is flushed out of the bowel using water squirted through a tube inserted into the rectum. This complementary therapy may sound like a new health fad, but it dates back to ancient Greece.