1 Address risk factors that can lead to coronary heart disease and other heart problems. 2  These risk factors include high blood pressure, high blood cholesterol, overweight or obesity, diabetes, smoking, lack of physical activity, and depression and other emotional health concerns. 3  Adopt healthy lifestyle changes.
Primary sclerosing cholangitis is often diagnosed before symptoms appear when a routine blood test or an X-ray taken for an unrelated condition shows liver abnormalities. Early symptoms often include: 1  Fatigue. 2  Itching.
Symptoms of cholecystitis can appear suddenly or develop slowly over a period of years. Signs and symptoms include: 1  severe abdominal pains that may feel sharp or dull. 2  abdominal cramping and bloating. 3  pain that spreads to your back or below your right shoulder blade. 4  fever. 5  chills. 6  nausea.7  vomiting. 8  loose, light-colored stools. 9  jaundice, which is when your skin and the whites of your eyes turn yellow.igns and symptoms include: 1  severe abdominal pains that may feel sharp or dull. 2  abdominal cramping and bloating. 3  pain that spreads to your back or below your right shoulder blade. 4  fever.