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Gene mutation on the X chromosome is most common and also explains why (depending on nationality) some 7% of males, but less than 1% of females exhibit color blindness of some form. Males only have one X chromosome, whereas females have two.
Colour blindness is a usually a genetic (hereditary) condition (you are born with it). Red/green and blue colour blindness is usually passed down from your parents. The gene which is responsible for the condition is carried on the X chromosome and this is the reason why many more men are affected than women.