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Can a molecule be both hydrophobic and hydrophilic? I think that's what soap (alkali salts of fatty acids)is all about. One end of these molecules attach to water molecules, the other end rejects water.(attaches to itself if ot â¦ her molecules of alkali salts of fatty acids are near by.)
The renin molecule contains both hydrophobic and hydrophilic amino acids. The hydrophilic ones tend to be on the outside of the molecule, while the hydrophobic ones tend to be more on the inside and form the active site, a large hydrophobic cavity that can accommodate a ligand with at least seven residues.