Gordon Lightfoot â The Wreck Of The Edmund Fitzgerald lyrics. The legend lives on from the Chippewa on down. Of the big lake they called 'Gitche Gumee'. The lake, it is said, never gives up her dead. When the skies of November turn gloomy. With a load of iron ore twenty-six thousand tons more.
Results: A total of 14 551 live births were analysed. After adjustment for confounding factors, taking huanglian during the first trimester of pregnancy was found to be associated with increased risk of congenital malformations of the nervous system (adjusted OR 8.62, 95% CI 2.54, 29.24).
Most common congenital malformations demonstratemultifactorial inheritance with a threshold effect and are determined by a combination of genetic andenvironmental factors. During the first two weeks of gestation, teratogenic agents usually kill theembryo rather than cause congenital malformations. Major malformations are more common inearly embryos than in newborns; however, most severely affected embryos are spontaneouslyaborted during the first six to eight weeks of gestation.