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Gene mutation on the X chromosome is most common and also explains why (depending on nationality) some 7% of males, but less than 1% of females exhibit color blindness of some form. Males only have one X chromosome, whereas females have two.
Any mutations that affect the above genes causes the color vision deficiency. For example, a mutation affecting the first two genes would cause a defect in detecting the green and red color of the light spectrum. This is one of the most prevalent forms of color blindness. slide 4 of 4.