To describe the natural history of a condition or disease. To describe the natural history of a condition or disease. To determine effectiveness or cost effectiveness of treatments/services and/or health care products. To measure or monitor safety and harm. To measure quality of care.
According to the NMSS, attacks or flare-ups of symptoms only qualify as exacerbations if: 1  they occur at least 30 days from an earlier flare-up. 2  symptoms last for 24 hours or longer.
I think the doses are a little lower (500mg to one gram) and it is given one or two days at a time (rather than daily for 3-5 days as is usually given to treat a MS flare). I believe this is called pulse therapy but that could apply to more than one kind of use.