To describe the natural history of a condition or disease. To describe the natural history of a condition or disease. To determine effectiveness or cost effectiveness of treatments/services and/or health care products. To measure or monitor safety and harm. To measure quality of care.
According to the NMSS, attacks or flare-ups of symptoms only qualify as exacerbations if: 1  they occur at least 30 days from an earlier flare-up. 2  symptoms last for 24 hours or longer.
However, the most common cause of these symptoms is a reaction to the injected steroid (âsteroid flareâ) which occurs in 2 to 5% of patients. A âsteroid flareâ usually begins 6-12 hours after the injection and may last for 2-3 days. Regardless of the cause, it is important to see a physician with these symptoms.ide-effects which rarely occur include: injury to the joint or tendon, loss of the fat layer below the skin, loss of skin pigmentation (vitiligo), calcification around the joint, and joint Infection (see below). The joint may âflare-upâ transiently after an injection.