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(3) renal â glutamine break down in proximal tubule (combines with H+ -> NH4+ and eliminated) CAUSES OF HYPERAMMONAEMIA. Overproduction of ammonia. Protein/ amino acid load. gastrointestinal hemorrhage. gastric bypass. multiple myeloma. allogeneic stem cell transplantation.
The main local problem of ammonia released into air is the unpleasant odour, which is detectable even at low concentrations. At particularly high concentrations it can also harm vegetation. The harm caused by ammonia in water bodies is more serious, because it is very toxic to aquatic organisms.