DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative anesthetic. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.
Aroldis Chapman has thrown the fastest pitch ever recorded, but he has challengers for baseball's hottest heater in 2017. Ever since Aroldis Chapman delivered a 105 mph fastball to Tony Gwynn Jr., Chapman's name has been synonymous with velocity.
And the winner is.... Nolan Ryan with a 108.1 MPH reading according to the doppler laser radar readings that were used in 1974. The Ryan Express was really bringing the heat that night in 1974, throwing the fastest pitch ever recorded in a Major League Baseball game.