Organic acids are ubiquitous throughout the field of chemistry. Whether used as a solvent, a substrate, a strong acid, or in a catalytic amount as a Bronsted acid source, organic acids are as commonplace as glassware for the researcher.
In the equation, p 2 represents the frequency of the homozygous genotype AA, q 2 represents the frequency of the homozygous genotype aa, and 2pq represents the frequency of the heterozygous genotype Aa. In addition, the sum of the allele frequencies for all the alleles at the locus must be 1, so p + q = 1.
This can be found by adding the count for all of the blood type alleles and multiplying by 2. In this example, the total allele count is: 2 x (250 + 550 + 150) = 1900. In order to determine the allele frequency, choose an allele, in this case A or B, count the number of that type of allele and then divide this by the total allele count.