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Can a molecule be both hydrophobic and hydrophilic? I think that's what soap (alkali salts of fatty acids)is all about. One end of these molecules attach to water molecules, the other end rejects water.(attaches to itself if ot â¦ her molecules of alkali salts of fatty acids are near by.)
There are about 10 nonpolar amino acids with R-groups that are not stable when in contact with water. They are hydrophobic. About 5 amino acids have polar side chains, R-groups which do not ionize or become positively or negatively charged. These R-groups are neither strongly hydrophilic nor hydrophobic. Atoms in long molecules, such as polypeptides, are not rigidly fixed in space or position.