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Gene mutation on the X chromosome is most common and also explains why (depending on nationality) some 7% of males, but less than 1% of females exhibit color blindness of some form. Males only have one X chromosome, whereas females have two.
Confidence votes 3. It is well known that people who are colorblind have mutations in their genes that cause a loss of either red or green cones, and they therefore have a hard time distinguishing between colors. There are three kinds of cones in the human eye: red, green, and blue.ow researchers have discovered that some people with the gene mutation that causes colorblindness lose an entire set of color cones with no detriment to the acuity of their vision overall.