Biological therapies for rheumatoid arthritis. Biological therapies (or biologics) are newer drugs which target individual molecules involved in the processes of inflammation and joint damage. Several of them (anti-TNF drugs) target a protein called tumour necrosis factor â for example:
June Gable. June Gable (born on June 5, 1945) is an American character actress, perhaps best known for her role as Joey's agent Estelle Leonard in the NBC sitcom Friends. She received one Tony Award nomination for her work on Broadway.
Talk0 Share. The One Where Estelle Dies is the fifteenth episode of the tenth season of Friends, which aired on April 22, 2004. Too much bad stuff is happening around Joey - his best friends are moving into a new house, Rachel is moving to Paris for her new job, and to make it even worse, his agent, Estelle, dies.