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Pathophysiology. The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen.
background. Mucormycosis, also known as zygomycosis, is an aggressive, opportunistic fungal infection of the sinuses, skin, gastrointestinal tract, brain or lungs that usually affects individuals who are immunocompromised.epending on where the fungal spores are deposited, mucormycosis may affect the sinuses, lungs, gastrointestinal tract, brain or skin. Most mucormycosis infections are life threatening. Most patients who have mucormycosis experience severe infections of the facial sinuses, which may extend into the brain.