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This history of the Byzantine Empire covers the history of the eastern Mediterranean empire from late antiquity until the Fall of Constantinople in 1453 AD. Several events from the 4th to 6th centuries mark the transitional period during which the Roman Empire's east and west divided.
It can be argued that some of the changes across the Macedonian Empire after Alexander's conquests and during the rule of the Diadochi would have occurred without the influence of Greek rule. As mentioned by Peter Green, numerous factors of conquest have been merged under the term Hellenistic Period.