To describe the natural history of a condition or disease. To describe the natural history of a condition or disease. To determine effectiveness or cost effectiveness of treatments/services and/or health care products. To measure or monitor safety and harm. To measure quality of care.
According to the NMSS, attacks or flare-ups of symptoms only qualify as exacerbations if: 1  they occur at least 30 days from an earlier flare-up. 2  symptoms last for 24 hours or longer.
Lymes growth phase occurs approximately every three to four weeks (up to six weeks maximum), and therefore, intermittent symptom flare-ups or Herxes usually also will occur at those same intervals. These cyclerelated Herxes continue to occur over time until a sufficient quantity of Bb has been killed off.