I second that âwaterâ idea. Prunes are most effective if you eat them, and then drink one cup of water â that usually gives both your body, and the prunes enough water to soften your stools. If that doesnât work, wellâ¦ I really donât know what to say.
Abstract. The most common cystic fibrosis transmembrane conductance regulator (CFTR) mutant in cystic fibrosis patients, Î´F508 CFTR, is retained in the endoplasmic reticulum (ER) and is consequently degraded by the ubiquitin-proteasome pathway known as ER-associated degradation (ERAD).
A gene on chromosome 7 is responsible for the normal production of a protein called cystic fibrosis transmembrane regulator (CFTR). Mutations (defects at the DNA level) in this gene lead to absent or defective CFTR production, causing CF.ystic fibrosis (CF) is a relatively common genetic disease caused by mutations in a gene located on chromosome 7. Every cell in the body (except sperm in men and egg cells, oocytes, in females) has 46 chromosomes, or 23 pairs of chromosomes, one half inherited from the mother and the other half from the father.