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Pathophysiology. The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen.
Colonic volvulus is a condition whereby the twisting of a movable segment of the bowel around its mesenteric axis results in a partial or complete colonic obstruction, possible injury to the bowel, and potential tissue death due to a lack of oxygen-rich blood from the compromised state of the blood supply.olonic volvulus is also known as twisted colon, bowel torsion, torsion of the ascending colon, closed-loop obstruction of the ascending colon and cecum, axial torsion, cecal bascule, cecal volvulus, sigmoid volvulus, or transverse volvulus. There are generally three types of colonic volvulus, or twisted colon.