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A histiocytoma is a benign skin tumor that originates in the Langerhans cells, immune cells that function to provide protective immunity to the tissues that are in contact with the outer environment -- the nose, stomach, intestines and lungs, but mainly the skin's surface. histiocytoma is a benign skin tumor that originates in the Langerhans cells, immune cells that function to provide protective immunity to the tissues that are in contact with the outer environment -- the nose, stomach, intestines and lungs, but mainly the skin's surface.
GENERAL INFORMATION. Benign Fibrous Histiocytoma is a rare tumor of mesenchymal origin. First described in 1958 by Dahlin. They are composed of two cell types, namely atypical fibroblasts and histiocytes, arranged in a storiform pattern.Lipid-filled cells may be conspicuous and occasionally are the major component.These types of benign fibrous histiocytomas are known as xanthomas or fibroxanthomas.hey are composed of two cell types, namely atypical fibroblasts and histiocytes, arranged in a storiform pattern. Lipid-filled cells may be conspicuous and occasionally are the major component. These types of benign fibrous histiocytomas are known as xanthomas or fibroxanthomas.