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From there, blood makes its way to the Vena cava, the largest vein in the body to return to the heart. Portal hypertension describes elevated pressure within the portal system, including the portal vein and the tributary veins that drain into it.
Portal hypertension is a serious increase in blood pressure in the portal vein system in the liver. Portal hypertension can be a complication of cirrhosis of the liver or alcoholic hepatitis. If the vessels in the liver are blocked by disease, it is hard for the blood to flow, causing high pressure in the portal system.