Holden /hold-en/ [2 sylls.] as a boys' name is pronounced HOHL-den. It is of Old English origin, and the meaning of Holden is deep valley. The hero of JD Salinger's novel The Catcher in the Rye is named Holden Caulfield.ariations. Holden is an uncommon given name for males but a very popular last name for both adults and children (#940 out of 150436, Top 1%).
Delta-9-tetrahydrocannabinol (Î´9-THC, THC) and delta-8-tetrahydrocannabinol (Î´8-THC), mimic the actions of anandamide and 2-arachidonoylglycerol, neurotransmitters produced naturally in the body. These cannabinoids produce the effects associated with cannabis by binding to the CB1 cannabinoid receptors in the brain.
Studies in mice and rats have shown that cannabinoids may inhibit tumor growth by causing cell death, blocking cell growth, and blocking the development of blood vessels needed by tumors to grow. Laboratory and animal studies have shown that cannabinoids may be able to kill cancer cells while protecting normal cells. A study in mice showed that cannabinoids may protect against inflammation of the colon and may have potential in reducing the risk of colon cancer, and possibly in its treatment. A laboratory study of delta-9-THC in hepatocellular carcinoma (liver cancer) cells showed that it damaged or killed the cancer cells. The same study of delta-9-THC in mouse models of liver cancer showed that it had antitumor effects.