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(3) renal â glutamine break down in proximal tubule (combines with H+ -> NH4+ and eliminated) CAUSES OF HYPERAMMONAEMIA. Overproduction of ammonia. Protein/ amino acid load. gastrointestinal hemorrhage. gastric bypass. multiple myeloma. allogeneic stem cell transplantation.
Ammonia poisoning is a very real threat to your fish, especially when the tank is new and is still cycling or if the tank has been stressed and the biological filter has been upset or removed. Ammonia stress is caused by two occurrences in the aquarium chemistry. First is the build up of toxic ammonia and nitrite in the water. This directly affects the fish and can have a number of harmful side effects - from increased disease susceptibility to organ failure. The second component of ammonia stress is the displacement of oxygen in the water by the ammonia.