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Lymphadenopathy is a condition where the lymph nodes, small round organs found all over the body, begin to swell, which could cause painful lump behind ear. The swelling is caused by accumulation of immune cells within the lymph node.
The bone that can be felt immediately behind the ear is called the mastoid. Acute mastoiditis is infection of this bone, caused by prior acute otitis media. The symptoms include reddened and swollen skin over the mastoid, fever, discharge from the ear and intense pain. This is a serious condition.