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Pesticide resistance is the ability of a pest population, such as insects, fungi, weeds or rodents, to evolve a tolerance to a pesticide that it was previously susceptible to. Retrieved from http://en.wikipedia.org/wiki/Pesticide_...
Rating Newest Oldest. Best Answer: Resistance means that the pesticide doesn't work and the long term effect is that whatever you are trying to protect from those pests will be destroyed by them because the pesticide doesn't kill them.