Not to be confused with Granulation tissue. Granuloma is an inflammation found in many diseases. It is a collection of immune cells known as histiocytes (macrophages). Granulomas form when the immune system attempts to wall off substances it perceives as foreign but is unable to eliminate.
Bittercube bitters are handcrafted in Milwaukee. Bitters add a unique flavor to any drink. Bitters are like the spice rack of the cocktail world, according to Ira Koplowitz, co-founder of Bittercube. When cooking with spices, drastically different flavor profiles can be achieved with varying spice blends, he said. The same can be said for bitters.. More literally speaking, bitters are a liquid extraction of seeds, herbs, bark, roots, flowers, leaves and fruit of various plants. They are highly concentrated and are used by the dash to flavor cocktails.
(plural bittersweets) 1  A vine, of the genus Celastrus, having small orange fruits that open to reveal red seeds. 2  The bittersweet nightshade, Solanum dulcamara. 3  A variety of apple with a bittersweet taste.