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Causes of purpura rash. The direct cause of purpura is blood in the skin which has leaked from blood vessels, which is what makes the little purplish-red dots or blisters to appear. This bleeding can be the result of several different causes.AIN Health Rashes Purpura Rash. Blood blisters caused by purpura. Purpura, which is also known as skin hemorrhages and blood spots, is a rash which appears as an outbreak of red dots on the skin.
(See also Overview of Vascular Bleeding Disorders.) Senile purpura causes ecchymoses and results from increased vessel fragility due to connective tissue damage to the dermis caused by chronic sun exposure, aging, and drugs. Purpura refers to purplish cutaneous or mucosal lesions caused by hemorrhage. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. Senile purpura typically affects elderly patients as their dermal tissues atrophy and blood vessels become more fragile. Patients develop persistent dark purple ecchymoses, which are characteristically confined to the extensor surfaces of the hands and forearms.