Anyone taking antimalarial drugs to prevent malaria who develops a fever or flu-like symptoms while taking the medicine or within 2-3 months after traveling to an area where malaria is common should call a physician immediately.
Treatment of knee pain depends on the cause of the knee pain. If you have been working on your knees all day then potentially rest and anti-inflammatories such as ibuprofen can help. If the cause is trauma and there is possible joint damage then you should seek medical attention.
1 For acute injuries, you may have to stay off your feet as much as possible or even use crutches for a short time.  Ice. Put ice on your knee for 15 to 20 minutes a few times each day. Use ice cubes or a bag of frozen vegetables wrapped in a towel.