1 Address risk factors that can lead to coronary heart disease and other heart problems. 2  These risk factors include high blood pressure, high blood cholesterol, overweight or obesity, diabetes, smoking, lack of physical activity, and depression and other emotional health concerns. 3  Adopt healthy lifestyle changes.
Primary sclerosing cholangitis is often diagnosed before symptoms appear when a routine blood test or an X-ray taken for an unrelated condition shows liver abnormalities. Early symptoms often include: 1  Fatigue. 2  Itching.
Symptoms include the following: 1  Charcot's triad consists of fever, RUQ pain, and jaundice. It is reported in up to 50-70% of patients with cholangitis. 2  Fever is present in approximately 90% of cases. 3  Abdominal pain and jaundice is thought to occur in 70% and 60% of patients, respectively.