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About 8, 9, 10 weeks. After about 8, 9, 10 weeks of age, or when the puppy arrives at it's new home, the dog should be taught to go potty outside. Do not have paper or potty pads inside your home. Peeing is for outside only, or you are teaching your new pup it is okay to potty inside your home.
Preventive treatment should begin at 6 or 8 weeks of age in puppies and after tests have been conducted in older dogs to determine if your dog has already been infected. If your dog does have heartworms, your veterinarian can advise you about treatment options.