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From there, blood makes its way to the Vena cava, the largest vein in the body to return to the heart. Portal hypertension describes elevated pressure within the portal system, including the portal vein and the tributary veins that drain into it.
Portal hypertension. When cirrhosis has led to severe scarring of the liver, blood is prevented from flowing through the organ easily. This causes pressure to build up in the vein that supplies the liver with blood. This is called the portal vein and the increased pressure is referred to as portal hypertension.