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This history of the Byzantine Empire covers the history of the eastern Mediterranean empire from late antiquity until the Fall of Constantinople in 1453 AD. Several events from the 4th to 6th centuries mark the transitional period during which the Roman Empire's east and west divided.
Making the world better, one answer at a time. There were many causes of the decline of the Byzantine Empire. The division and separation of its religion, Orthodox Christianity, with the Catholic Papacy of the west would prove lethal on the long run. The loss of the theme system which provided the empire with immediate military protection in case of invasions.