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Dark urine. Glimepiride can cause low blood sugar (hypoglycemia) in some people. This is more common in elderly people and in people with adrenal, pituitary, liver, or kidney problems, as well as during fasting before surgery and after prolonged exercise.
Kidney damage is a problem in 10-25% of people who receive aminoglycosides, and gentamicin is one of the most nephrotoxic of the class. Oftentimes acute nephrotoxicity is reversible, but it may be fatal.