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(3) renal â glutamine break down in proximal tubule (combines with H+ -> NH4+ and eliminated) CAUSES OF HYPERAMMONAEMIA. Overproduction of ammonia. Protein/ amino acid load. gastrointestinal hemorrhage. gastric bypass. multiple myeloma. allogeneic stem cell transplantation.
High ammonia levels can occur for a variety of reasons. Causes for elevated ammonia in your blood include liver disease, liver failure, hepatitis, liver cirrhosis, Reyeâs syndrome in children, intestinal bleeding, cardiovascular conditions, kidney complications and a rare, inherited disorder of the urea cycle called Citrullinemia.