Organic acids are ubiquitous throughout the field of chemistry. Whether used as a solvent, a substrate, a strong acid, or in a catalytic amount as a Bronsted acid source, organic acids are as commonplace as glassware for the researcher.
In the equation, p 2 represents the frequency of the homozygous genotype AA, q 2 represents the frequency of the homozygous genotype aa, and 2pq represents the frequency of the heterozygous genotype Aa. In addition, the sum of the allele frequencies for all the alleles at the locus must be 1, so p + q = 1.
If, , and are the frequencies of the three genotypes at a locus with two alleles, then the frequency p of the A-allele and the frequency q of the B-allele in the population are obtained by counting alleles.he frequency (p) of an allele A is the fraction of the number of copies (i) of the A allele and the population or sample size (N), so.