1 Address risk factors that can lead to coronary heart disease and other heart problems. 2  These risk factors include high blood pressure, high blood cholesterol, overweight or obesity, diabetes, smoking, lack of physical activity, and depression and other emotional health concerns. 3  Adopt healthy lifestyle changes.
Primary sclerosing cholangitis is often diagnosed before symptoms appear when a routine blood test or an X-ray taken for an unrelated condition shows liver abnormalities. Early symptoms often include: 1  Fatigue. 2  Itching.
Cholangitis symptoms can be very serious. Most patients with cholangitis symptoms are very sick. Cholangitis symptoms develop when there is an infection and obstruction in the common bile duct and the biliary tract. In patients with cholangitis symptoms, bile can not flow down into duodenum from the liver and back flow of bile into the liver and ultimately into blood occurs.