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Symptoms of Bernard-Soulier Syndrome. The list of signs and symptoms mentioned in various sources for Bernard-Soulier Syndrome includes the 12 symptoms listed below: Excessive bleeding following injury. Frequent nosebleeds. Heavy menstrual flow. Easy bruising. Slow-healing bruises. Skin hemorrhage. Sbucutaneous bleeding.
The symptoms of Krabbe disease usually begin before the age of 1 year (the infantile form). Initial signs and symptoms typically include irritability, muscle weakness, feeding difficulties, episodes of fever without any sign of infection, stiff posture, and slowed mental and physical development.rabbe disease is part of a group of disorders known as leukodystrophies, which result from the loss of myelin (demyelination). This disorder is also characterized by the abnormal presence of globoid cells, which are globe-shaped cells that usually have more than one nucleus.