In 2016, you paid $600 interest on a car loan. During 2016, you used the car 60% for business and 40% for personal purposes. You are claiming actual expenses on the car. You can only deduct $360 (60% Ã $600) for 2016 on Schedule C or C-EZ. The remaining interest of $240 is a nondeductible personal expense.
A nonsense mutation is a point mutation that introduces a premature stop codon into the part of the gene that encodes a protein. A stop codon is like a period at the end of a sentence: it instructs the ribosome to stop making the protein.
Thus, nonsense mutations occur when a premature nonsense or stop codon is introduced in the DNA sequence. When the mutated sequence is translated into a protein, the resulting protein is incomplete and shorter than normal. Consequently, most nonsense mutations result in nonfunctional proteins.