In E. coli the main enzyme is DNA polymerase III and the enzyme that replaces the RNA primer with DNA is DNA polymerase I. When the RNA primer has been replaced with DNA, there is a gap between the two Okazaki fragments and this is sealed by DNA ligase.
Little Richard's Tutti Frutti (1955) was included in the National Recording Registry of the Library of Congress in 2010, which stated that his unique vocalizing over the irresistible beat announced a new era in music..
Elvis Presley recorded the song and it was included in his first RCA album Elvis Presley March 23, 1956. Elvis' cut of Tutti Frutti was also released as an EP and as a single (RCA 47-6636) where it was listed by Billboard magazine as in the Top 20 in sales.