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This small nucleus contains almost half of all the brain neurons that use norepinephrine as a neurotransmitter. The locus coeruleus also projects its axons to those parts of the brain that may be associated with panic disorders (the amygdala, hippocampus, septum, cortex, brainstem, reticular formation, etc). Stimulating an animal's locus coeruleus, like stimulating its amygdala, produces anxiety behaviours.
Stress, anxiety, and fear may produce responses from the amygdala. The amygdala and hippocampus are two parts of the brain responsible for the processing of memories. Patients with Alzheimer's disease often have damage in the hippocampus.The hippocampus and amygdala are both located under the hypothalamus.he amygdala and hippocampus rely on each other to form their individual functions. Responses to stimuli are regulated by the amygdala and those responses are then used by the hippocampus in the formation of both short-term and long-term memories.