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This small nucleus contains almost half of all the brain neurons that use norepinephrine as a neurotransmitter. The locus coeruleus also projects its axons to those parts of the brain that may be associated with panic disorders (the amygdala, hippocampus, septum, cortex, brainstem, reticular formation, etc). Stimulating an animal's locus coeruleus, like stimulating its amygdala, produces anxiety behaviours.
Anxiety and the Brain. There are a number of factors that have been identified by specialists as being related to anxiety. The brain of an overly anxious person is already more sensitive to stress. When the body is confronted with a perceived threat in the environment, the brain prepares it to react.earning about the Brain Chemistry of Mental Health. It is important for people with anxiety disorders to understand whatâs happening to them when they experience stress. Family and friends of anxious people also need to be educated on the biology of anxiety.