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Overview. Plague is an infectious disease caused by bacteria called Yersinia pestis. These bacteria are found mainly in rodents, particularly rats, and in the fleas that feed on them. Other animals and humans usually contract the bacteria from rodent or flea bites. Historically, plague destroyed entire civilizations.
By Jerrod R Anderson. Disease etiology. Plague is an infectious disease of animals and humans caused by a bacterium named Yersinia pestis. (1) There are three different types of plague, Bubonic, the most commonly plague found in humans, Septicemic and Pneumonic.(2). Disease transmission. The disease is transmitted via animals or insect vectors and are injected into humans or animals via a flea bite, or a bite from infected animals or rodents.his particular plague differed from the first two in the fact that it was not only bubonic plague, but it was also pneumonic plague as well. The third pandemic lasted for over a century when it hit Hawaii in 1959. This pandemic is what eventually led to the modern treatment methods of plague.