In DIC, the processes of coagulation and fibrinolysis are dysregulated, and the result is widespread clotting with resultant bleeding. Regardless of the triggering event of DIC, once initiated, the pathophysiology of DIC is similar in all conditions. One critical mediator of DIC is the release of a transmembrane glycoprotein called tissue factor (TF).
Rigid polyurethane and polyisocyanurate foams will, when ignited, burn rapidly and produce intense heat, dense smoke and gases which are irritating, flammable and/or toxic. As with other organic materials the most significant gas is usually carbon monoxide. Thermal decomposition products from polyurethane foam, consist mainly of carbon monoxide, benzene, toluene, oxides of nitrogen, hydrogen cyanide, acetaldehyde, acetone, propene, carbon dioxide, alkenes and water vapor.
POLYFOAM, Polysocyanurate foam is manufactured in similar way to standard Polyurethane. POLYFOAM PIR has all the characteristics and advantages of rigid Polyurethane foam but offers greatly increased resistance to burning and spread of flame and is able to withstand temperatures up to 140Â°C. Fire performance-POLYFOAM PUR/PIR is usually used at lower thicknesses than other insulants, so that their heat or fuel contribution to a fire is low compared to other thicker insulating materials. 2  Enhanced compressive and tensile strength at cryogenic temperatures make it resistant cracking.