Eustachian Tube Growth and Development: Anatomy/Function. Protocol Description. This study measures Eustachian tube function and facial growth over time in three groups of children: one with recurrent ear infections, one with chronic middle ear fluid, and one with little past history of otitis media.
Causes of Kartagener syndrome. Kartagener syndrome is caused by a mutation in the DNAI1 gene, which makes a cellular protein required for normal functioning cilia (cilia line the respiratory tract) and sperm motility.
A third NRTI class resistance signature is the T215Y mutation, plus a single change at codon 67, plus a double insertion between codons 68 and 69. People with this pattern have shown phenotypic resistance to AZT, 3TC, ddI, and d4T despite the absence of other mutations usually associated with these agents.