Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calcium channels (VDCCs) located in the central nervous system (CNS).
Hexane /ËhÉkseÉªn/ is an alkane of six carbon atoms, with the chemical formula C 6 H 14. typical laboratory use of hexanes is to extract oil and grease contaminants from water and soil for analysis. Since hexane cannot be easily deprotonated, it is used in the laboratory for reactions that involve very strong bases, such as the preparation of organolithiums.
Hexane is a neurotoxicant and is often used as a narcotic as well. Nearly all those affected by hexane are workers (#ATSDR ToxFAQs). Acute exposure to hexane leads to numbness in the extremities, dizziness, confusion, nausea, headache, and irritation of the eyes, nose, throat, and skin (#OSHA and #ATSDR ToxFAQs).