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OPANAÂ® ER is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use.
Opana (Oxymorphone) also comes in an extended release formula (Opana ER) for patients in need of pain relief around the clock. Opana is classified as a schedule II analgesic opioid drug because the potential for abuse is high and can lead to severe psychological and physical dependence if abused.