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From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. The part of an antibody that binds to the epitope is called a paratope.
In immunology, an antigen (Ag) is any structural substance that serves as a target for the receptors of an adaptive immune response, TCR or BCR or its secreted form antibody.ifferent antibodies have the potential to discriminate among specific epitopes present on the antigen surface. Hapten is a small molecule that changes the structure of an antigenic epitope. In order to induce an immune response, it has to be attached to a large carrier molecule such as a protein.