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Refrigerator Method. (Recommended). Frozen beef should not be defrosted at room temperature. Harmful bacteria may grow rapidly under such conditions. The best method for thawing beef (or any other type of meat) is to place it in the refrigerator where it will defrost slowly and safely.round Beef. (one pound bulk). Defrost in the refrigerator for: 24 hours. Additional Thawing and Defrosting Tips. 1  Beef that is not fully defrosted should not be cooked because the exterior of the beef may become overdone before the interior has had a chance to cook to the proper temperature.
1 Ground beef that has been defrosted in the fridge can be kept for an additional 1 to 2 days in the refrigerator before cooking; ground beef that was thawed in the microwave or in cold water should be cooked immediately. How long does raw ground beef last at room temperature? 2  Bacteria grow rapidly at temperatures between 40 Â°F and 140 Â°F; ground beef should be discarded if left for more than 2 hours at room temperature.