In E. coli the main enzyme is DNA polymerase III and the enzyme that replaces the RNA primer with DNA is DNA polymerase I. When the RNA primer has been replaced with DNA, there is a gap between the two Okazaki fragments and this is sealed by DNA ligase.
Little Richard's Tutti Frutti (1955) was included in the National Recording Registry of the Library of Congress in 2010, which stated that his unique vocalizing over the irresistible beat announced a new era in music..
Tutti Frutti (song) From Wikipedia, the free encyclopedia. For other entries on Tutti Frutti, see Tutti frutti (disambiguation). Tutti Frutti (meaning all fruit in Italian) is a song written by Little Richard along with Dorothy LaBostrie that was recorded in 1955 and became his first major hit record.