In E. coli the main enzyme is DNA polymerase III and the enzyme that replaces the RNA primer with DNA is DNA polymerase I. When the RNA primer has been replaced with DNA, there is a gap between the two Okazaki fragments and this is sealed by DNA ligase.
Little Richard's Tutti Frutti (1955) was included in the National Recording Registry of the Library of Congress in 2010, which stated that his unique vocalizing over the irresistible beat announced a new era in music..
Cite This Source. Meaning. The story of Tutti Frutti is one of the most essential stories in the history of rock and roll. The song hit the airwaves in 1955, just as the whole new-fangled idea of a type of music called rock and roll was starting to dig its heels into popular culture.