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The average lead time for invitations is six to eight weeks before the wedding; however, destination-wedding invites should be sent anywhere from two to three months ahead of time. If you sent a save-the-date, an invitation is expected to follow.
Traditionally, invitations go out six to eight weeks before the wedding -- that gives guests plenty of time to clear their schedules and make travel arrangements if they don't live in town. If it's a destination wedding, give guests more time and send them out three months ahead of time.