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OPANAÂ® ER is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use.
Oxymorphone (Opana) is an expensive drug used to treat moderate to severe pain. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic oxymorphone is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.