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1. karyotype-the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes). physical composition, composition, make-up, makeup, constitution-the way in which someone or something is composed. Translations.
Best Answer: A karyotype is a visual diagram of a person's chromosomes. It can be used to determine if a baby will have a genetic disorder or what specific genetic disorder a person has or will have. In pedigrees for autosomal genes, each parent has two alleles for a trait, for example, two letters in their genotype (Pp or PP or pp).