Some jurists and scholars use natural law synonymously with natural justice or natural right (Latin ius naturale), while others distinguish between natural law and natural right. Natural law theories have exercised a profound influence on the development of English common law.
Compared with triptorelin and an antiandrogen, degarelix was associated with an incremental cost of Â£59,012 per QALY gained. The probabilistic sensitivity analysis showed that at a willingness-to-pay threshold of Â£30,000 per additional QALY gained, degarelix was cost-effective in less than 10% of simulations.
The GnRH antagonist abarelix was withdrawn from the US market in 2005 and is now only marketed in Germany for use in patients with symptomatic prostate cancer. Degarelix is a GnRH antagonist that is approved for use in patients with advanced hormone-sensitive prostate cancer throughout Europe and also in the USA.