Word Origin and History for mesopotamian. ancient name for the land that lies between the Tigris and Euphrates rivers (in modern Iraq), from Greek mesopotamia (khora), literally a country between two rivers, from fem. of mesopotamos, from mesos middle (see medial (adj.)) + potamos river (see potamo-).
Monogenic forms, caused by a single mutation in a dominantly or recessively inherited gene, are well-established, albeit relatively rare types of PD. They collectively account for about 30% of the familial and 3%â5% of the sporadic cases.
Monogenic diseases When a hereditary disease is caused by an anomaly in a single gene one speaks of a monogenic disease. When a disease it is caused by an interaction between several genes and environmental factors, one speaks of a multifactorial disease. Below monogenic diseases and their inheritance are discussed.herefore, the mode of inheritance of a monogenic disease is defined by the position of the mutated gene. On the other hand one can also derive the mode of inheritance of the disease by studying the transmission within the family. The geneticist or genetic counseler therefore makes a family pedigree.