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1. karyotype-the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes). physical composition, composition, make-up, makeup, constitution-the way in which someone or something is composed. Translations.
The term karyotype refers to the basic map, or picture, of the number,type, and structure of the chromosomes of a cell. The karyotype is created through a process in which a cell s mitotic division is halted or trapped during metaphase and held suspended by chemicals.