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myasthenia gravis myasthenia gravÂ·is (grÄv'Ä­s) n. A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors. Also called Goldflam disease.
The name myasthenia gravis, which is Latin and Greek in origin, literally means grave muscle weakness. With current therapies, however, most cases of myasthenia gravis are not as grave as the name implies. In fact, most individuals with myasthenia gravis have a normal life expectancy.