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Best Answer: That DNA is antiparallel means that the two strands of DNA have opposite chemical polarity, or, stated another way, their sugar-phosphate backbones run in opposite directions.
Answers. Relevance. Rating Newest Oldest. Best Answer: The two strands are antiparallel because of the complementarity of the nucleobases that comprise them: DNA is comprised of four nucleobases or bases: cytosine, guanine, adenine, and thymine. The thing is, they pair up with each other in only one way: C-G and A-T, and vice verse.