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In some cases, a tissue type test may be done to see whether a person has a chance for developing certain diseases that cause the body to attack its own cells, such as autoimmune diseases. A special pattern of antigens (called tissue type) is present on each person's cells and tissues.
Two main antigen groups are used for a tissue type test. Class I has three classes of antigens (HLA-A, HLA-B, HLA-C) that are found on some kinds of blood cells. Class II has one class of antigens (HLA-D) that are found only on certain cells in the body.There are many different types of antigens in each category. tissue type test is done to: 1  See if the antigen pattern for donated tissue or organs (including a blood platelet transfusion or bone marrow transplant) is a match. 2  See how likely two people are related. 3  Find people who may have a high chance of certain autoimmune diseases.