The total lesion load for hyperintense lesions on PD-weighted and fast FLAIR images and for hypointense lesions on T1-weighted and fast FLAIR images was measured by a single trained technician who was unaware of the patients' clinical characteristics.irst, hypointense lesion volumes on fast FLAIR images were, on average, only 1% to 2% of the volumes obtained from the corresponding PD-weighted images, and this is of some concern when such an approach is used for detecting changes of MS lesion burden over time.
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