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1 In large skillet, cook hamburger until brown. Mix spaghetti sauce into skillet. Reduce heat and simmer. 2  Meanwhile, bring a large pot of lightly salted water to a boil. Mix in pasta and cook for 8 to 10 minutes or until al dente; drain.  Mix together spaghetti and meat mixture, pour into 9x13 pan.
Add your sauce and cook on low for 8hrs. or high for 4 hrs. Brown them first on the stove, then leave them in the crockpot with a sauce for 3-4 hours. Depending on the kind of meat you use, and the extenders and binders, you could end up with spaghetti sauce instead of meatballs in sauce if you cook them too long.