The influx and outflux of ions (through ion channels during neurotransmission) will make the inside of the target neuron more positive (hence, de-polarized). When this depolarization reaches a point of no return called a threshold, a large electrical signal is generated. This is the action potential.
Pico Rivera, California. Pico Rivera is a city located in southeastern Los Angeles County, California, United States. The city is situated approximately 11 miles (18 km) southeast of downtown Los Angeles, on the eastern edge of the Los Angeles basin, and on the southern edge of the area known as the San Gabriel Valley.
As the population grew, so did residents' collective sense of civic duty and desire to blend the two separate towns. On January 7, 1958, the majority of voters in Pico and Rivera voted to incorporate as one municipality and with the decision becoming official that January 29, Pico Rivera became Los Angeles County's 61st city.