Social Security Timeline. 1  1935 The 37-page Social Security Act signed August 14 by President Franklin D. Roosevelt. 2  1937 First Social Security Cards issued by post offices, over 20 million issued in first year. 3  1937 Ernest Ackerman receives first lump-sum payout (of 17 cents) in January.
The proportion of subjects who permanently discontinued treatment due to adverse events was 0%, less than 1%, and 1% for subjects receiving Harvoni for 8, 12, and 24 weeks, respectively. The most common adverse reactions (at least 10%) were fatigue and headache in subjects treated with 8, 12, or 24 weeks of Harvoni.
In a separate study of 647 patients with GT1 Hep C, with no prior Hep C treatment and without cirrhosis, 96% (208 out of 216) of those who received HARVONI once daily for 12 weeks were cured. These studies did not include patients with advanced cirrhosis (decompensated) or those who have had a liver transplant.