Eustachian Tube Growth and Development: Anatomy/Function. Protocol Description. This study measures Eustachian tube function and facial growth over time in three groups of children: one with recurrent ear infections, one with chronic middle ear fluid, and one with little past history of otitis media.
Causes of Kartagener syndrome. Kartagener syndrome is caused by a mutation in the DNAI1 gene, which makes a cellular protein required for normal functioning cilia (cilia line the respiratory tract) and sperm motility.
Example of Substitution Mutation: Sickle Cell Anaemia is caused by substitution mutation, where in codon (GAG mutates to --> GTG) and leads to (Glu --> Val) change. Insertions are mutations in which extra base pairs are inserted into a new place in the DNA.