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an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
In immunology, an antigen (Ag) is any structural substance that serves as a target for the receptors of an adaptive immune response, TCR or BCR or its secreted form antibody.n summary an antigen is a molecule that binds to Ag-specific receptors, but cannot induce an immune response in the body by itself.