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A decongestant (or nasal decongestant) is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract.The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed efficacy).These are alpha-agonists which on topical application as dilute solution (0.05-0.1%) produce local vasoconstriction.he active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed efficacy). These are alpha-agonists which on topical application as dilute solution (0.05-0.1%) produce local vasoconstriction.
Decongestants can temporarily relieve nasal congestion, but also slightly raise blood pressure during their usage - especially with decongestants containing the ingredient pseudoephedrine. Due to these small spikes in blood pressure, consult your physician if you have high blood pressure and wish to use decongestants. Decongestant uses. Nasal congestion has many different root causes, including colds, flu and allergies. You can take decongestants orally (by mouth) or as nasal sprays or drops.