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1 Urethral cancer is a disease in which malignant (cancer) cells form in the tissues of the urethra, the tube that carries urine from the bladder to outside the body. It is a rare cancer that occurs more often in women than in men.  Squamous cell carcinoma is the most common type of urethral cancer.
A urethral discharge may indicate a sexually transmitted disease (STD), and the color, type and amount of discharge should be determined. Bladder cancer can cause dysuria and hematuria. Prostate cancer rarely results in dysuria or other urinary symptoms.