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OPANAÂ® ER is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use.
Oxymorphone is a prescription medication is a narcotic and meant for treating moderate to severe pain. Itâs the generic name for medications including Opana, Opana ER and Numorphan HCI. Oxymorphone is said to act similar to morphine. Opana ER is the extended release version and used to treat moderate to severe, around-the-clock pain.