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OPANAÂ® ER is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use.
Opana (oxymorphone) is an opioid pain medication. An opioid is sometimes called a narcotic. Opana is used to treat moderate to severe pain. The extended-release form of this medicine is for around-the-clock treatment of severe pain. Opana ER is not for use on an as-needed basis for pain. Opana may also be used for purposes not listed in this medication guide.