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Best Answer: That DNA is antiparallel means that the two strands of DNA have opposite chemical polarity, or, stated another way, their sugar-phosphate backbones run in opposite directions.
DNA replication. In DNA, the 5' carbon is located at the top of the leading strand, and the 3' carbon is located at the lower section of the lagging strand. The nucleic acid sequences are complementary and parallel, but they go in opposite directions, hence the antiparallel designation.