Paracrine signaling produces molecules of a local regulator. Synaptic signaling produces neurotransmitters. Paracrine signaling affects all cells in the vicinity of the transmitting cell. Synaptic signaling affect a single target cell.
Sterling Jewelers, Inc. is an American specialty jewelry company headquartered in Akron, Ohio. The company was founded in 1910 by Henry Shaw (the father of Jerry Shaw, the chairman emeritus of Sterling today), from LeRoy's Jewelers in Lorain, Ohio.
Approximately 78% of company sales are derived from the 12 different store brands operating in the U.S. They include Kay Jewelers, Jared-The Galleria of Jewelry, J.B. Robinson, Marks & Morgan, and Belden Jewelers, among others (all of which operate as Sterling divisions).