At first, you may barely notice the symptoms of hypothyroidism, such as fatigue and weight gain, or you may simply attribute them to getting older. But as your metabolism continues to slow, you may develop more-obvious signs and symptoms. Hypothyroidism signs and symptom may include: Fatigue.
Studies have estimated that, in the United States, antibiotic resistance adds $20 billion in excess direct health care costs, with additional costs to society for lost productivity as high as $35 billion a year. The use of antibiotics is the single most important factor leading to antibiotic resistance.
Antibiotic resistance is found all over the world and has become a very serious problem in the treatment of disease. The 1995 US Office of Technology Assessment report attributed a cost of $1.3 billion (1992 dollars) per year for antibiotic-resistant infections due to six species of bacteria in US hospitals.