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Causes of Hemorrhage. Causes of Hemorrhage. Hemorrhage has many causes, including a bleeding disorder (e.g. hemophilia), a low platelet count, anticoagulant medications, a broken or ruptured blood vessel and severe trauma.
In elderly individuals, amyloid protein deposits along the blood vessels can cause the vessel wall to weaken leading to a hemorrhagic stroke. Cocaine or drug abuse can weaken blood vessels and lead to bleeding in the brain. Some prescription drugs can also increase the risk of brain hemorrhage.