Locations farthest away from Rome. 1  Chatham Islands, Chatham Islands, New Zealand, 11,960 mi. 2  Greymouth, New Zealand, 11,351 mi. 3  Rarotonga, Cook Islands, 10,938 mi.  Nukualofa, Tonga, 10,932 1  mi. Pangai, Tonga, 10,857  mi.
Side effects of DHEA have been acne, facial hair on women, cardiac irregularities, feeling of chest tightness, irritability, anxiety, headaches, and sleeplessness. In addition to these, DHEA can cause elevated liver enzymes which increases the ratio of total cholesterol to HDL cholesterol.
In an individual with compromised liver function, even small amounts of oils containing 1,8 cineole taken orally can cause dangerously elevated liver enzymes in a matter of a few days. There is also the matter of drug interactions. All essential oils have some sort of effect upon P450 liver detoxification enzymes. Some inhibit or accelerate phase 1 enzymes, some inhibit or accelerate phase 2 enzymes, and still some interact with both phase 1 and 2 enzymes. This does not pose a problem with the majority of essential oils when inhalation therapy or topical application is used, but does create problems with oral ingestion.