Introduction. On July 21, 1861, Union and Confederate armies clashed near Manassas Junction, Virginia, in the first major land battle of the American Civil War.mpact of Bull Run (Manassas). Despite their victory, Confederate troops were far too disorganized to press their advantage and pursue the retreating Yankees, who reached Washington by July 22.
Symptoms of Lyme Disease. Lyme disease occurs in three stages: early localized, early disseminated, and late disseminated. The symptoms you experience will depend on which stage the disease is in. Symptoms of Lyme disease start one to two weeks after the tick bite. One of the earliest signs is a âbullâs-eyeâ rash. This is a sign that bacteria are multiplying in the bloodstream. The rash occurs at the site of the tick bite as a central red spot surrounded by a clear spot with an area of redness at the edge.
The first symptom of Lyme disease in most people is an expanding red skin rash (called erythema migrans or an EM rash). In about a third of people, the rash looks like a bull's-eye, with a pale center area surrounded by a bright red rim. The rash is often accompanied by flu-like symptoms, including: 1  Fatigue (the most common symptom). 2  Headache and stiff neck. 3  Fever (which may be high in children, but this is rare). 4  Muscle and joint pain.