synthetic - involving or of the nature of synthesis (combining separate elements to form a coherent whole) as opposed to analysis; limnology is essentially a synthetic science composed of elements...that extend well beyond the limits of biology- P.S.Welch.
L-theanine is most effective in the range of 50-200 mg, with the effect being felt within 30 minutes and lasting for 8-10 hours. Individuals with high stress levels may increase their dosage of L-theanine to at least 100 mg, with no more than 600 mg being taken in a six hour period. FDA recommends a maximum dose of 1200 mg daily, although the reason for this limit is not clear, due to its demonstrated safety. There are no known adverse reactions to L-theanine and no drug interactions have been reported. L-theanine is not affected by food and may be taken anytime, as needed.
For example, in a double-masked field study (Rapoport. JL, et.al.; 1992), a mean fluoxetine dose range of 0.55 to 1.36 mg/kg of body. weight/day administered over five weeks produced a 39% (p<0.05) reduction in mean. licking behavior from baseline observations in fourteen dogs diagnosed with acral. lick dermatitis (ALD).