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Necrotizing enterocolitis (NEC) is a disease that develops when the tissue in the inner lining of the small or large intestine becomes damaged and begins to die. This causes the intestine to become inflamed.
In premature infants, the cause may be related to the immaturity of the childâs digestive system. NEC involves infection and inflammation in the childâs gut, which may stem from the growth of dangerous bacteria or the growth of bacteria in parts of the intestine where they do not usually live.