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The painful, burning sensation is caused by rising stomach acid. It moves from your stomach, where the lining is resistant to its corrosive effects, up into your esophagus, the lining of which is not similarly protected. It can climb all the way from the bottom of the esophagus all the way up into the throat.
Burning Sensation in Chest: Other Causes to Watch Out. Except heartburn and heart attack, here are other possible causes of that burning feeling in chest: 1. Esophagitis. This inflammation can destroy the tissues of the tube that carries foods from the mouth to the stomach (esophagus).