In E. coli the main enzyme is DNA polymerase III and the enzyme that replaces the RNA primer with DNA is DNA polymerase I. When the RNA primer has been replaced with DNA, there is a gap between the two Okazaki fragments and this is sealed by DNA ligase.
Little Richard's Tutti Frutti (1955) was included in the National Recording Registry of the Library of Congress in 2010, which stated that his unique vocalizing over the irresistible beat announced a new era in music..
Like Long Tall Sally, this song was covered by Elvis. Little Richard once said, Elvis may be the King of Rock and Roll, but I am the Queen.. (thanks, Brett-Edmonton, Canada). Little Richard did not invent the name Tutti Frutti; it was a popular flavor of ice cream. The phrase is Italian for All Fruits, and the ice cream had little bits of candied fruit mixed in.