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Best Answer: That DNA is antiparallel means that the two strands of DNA have opposite chemical polarity, or, stated another way, their sugar-phosphate backbones run in opposite directions.
At the other end there is a 3â-OH group which is where a free hydroxyl group is attached to a deoxyribose sugar. The DNA chains are so arranged that you can never have two 5â (five prime) or 3â (three prime) at one end. This arrangement is called antiparallel, the strands run in opposite directions to each other. In the case of circular DNA strands, which are mostly found in bacteria or viruses â though the structure is circular, there occurs some kind of polarity in the individual strand.