showing, using, or characterized by caution: a cautious man; To be cautious is often to show wisdom. Origin of cautious. 1630-1640.
A sedentary lifestyle increases the risk of developing diabetes, hypertension, colon cancer, depression and anxiety, obesity, and weak muscles and bones. According to the CDC, nationally in 2000, 78% of the population was at risk for health problems related to lack of exercise, which is regular and sustained physical activity.
I'm agree with how everyone has responded so far. These consequences are often due to the cumulative effects of leading a sedentary lifestyle finally taking their toll. Michael's link lists some of the major ones (i.e. obesity, back problems, etc.). Simple in form, yet it alludes to such a complex dilemma.