Eustachian Tube Growth and Development: Anatomy/Function. Protocol Description. This study measures Eustachian tube function and facial growth over time in three groups of children: one with recurrent ear infections, one with chronic middle ear fluid, and one with little past history of otitis media.
Causes of Kartagener syndrome. Kartagener syndrome is caused by a mutation in the DNAI1 gene, which makes a cellular protein required for normal functioning cilia (cilia line the respiratory tract) and sperm motility.
BirtâHoggâDube syndrome is an autosomal dominant condition of lung cysts, benign skin tumours and renal cell carcinoma. Cysts can rupture to cause pneumothorax. Causative mutations are found in the Folliculin gene. Some Folliculin gene mutations appear to cause only the cystic lung disease without other features of BirtâHoggâDube syndrome, as in the case illustrated. Note the irregular thinâwalled cysts (arrow heads).