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an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shape protein produced by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses.The antibody recognizes a unique molecule of the harmful agent, called an antigen, via the variable region.he ability of an antibody to communicate with the other components of the immune system is mediated via its Fc region (located at the base of the Y), which contains a conserved glycosylation site involved in these interactions.