Surfactant is a complex substance containing phospholipids and a number of apoproteins. This essential fluid is produced by the Type II alveolar cells, and lines the alveoli and smallest bronchioles. Surfactant reduces surface tension throughout the lung, thereby contributing to its general compliance. It is also important because it stabilizes the alveoli.
Stagnant anoxia occurs when there is interference with the blood flow, although the blood and its oxygen-carrying abilities are normal. A common cause of general stagnant anoxia is heart disease or interference with the return of blood flow through the veins.
Anemia and blood loss are the most common causes of this type of hypoxia. Other possible causes include exposure to carbon monoxide, nitrites, and sulfa drugs, which form compounds with and reduce the amount of hemoglobin available to combine with oxygen.