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Best Answer: That DNA is antiparallel means that the two strands of DNA have opposite chemical polarity, or, stated another way, their sugar-phosphate backbones run in opposite directions.
3' end. DNA is made of antiparallel strands, meaning that while one strand runs from 3' to 5', its complementary strand (the other half of the double helix, in other words) runs from 5' to 3'. The two strands are parallel, but running in opposite directions.