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From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. The part of an antibody that binds to the epitope is called a paratope.
Antibodies recognize specific antigens by identifying certain areas on the surface of the antigen known as antigenic determinants. Once the specific antigenic determinant is recognized, the antibody will bind to the determinant.The antigen is tagged as an intruder and labeled for destruction by other immune cells.ntibodies protect against substances prior to cell infection. Antibodies are produced by a type of white blood cell called a B cell (B lymphocyte). B cells develop from stem cells in bone marrow.