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Seroquel is the brand name of the generic drug quetiapine, used to treat schizophrenia and bipolar disorder (formerly known as manic-depression). Seroquel changes the levels of neurotransmitters (naturally occurring brain substances) including serotonin and dopamine.
Seroquel belongs to a class of medications called atypical antipsychotics. The Food and Drug Administration (FDA) approved quetiapine in 1997 under the brand name Seroquel for drug manufacturer AstraZeneca. Two years earlier, AstraZeneca agreed to pay $520 million to settle federal investigations into the drugmaker's marketing practices for Seroquel.