In simple linear regression a single independent variable is used to predict the value of a dependent variable. In multiple linear regression two or more independent variables are used to predict the value of a dependent variable. The difference between the two is the number of independent variables.
Watching for Systemic Symptoms. 1  1. Watch from swollen glands. Serious cases of cellulitis will spread beyond the initially infected region to become systemic and impact the rest of the body. 2  2. Notice if you experience fever and/or chills.
Cellulitis can occur by this route anywhere there is a break in the skin. It can also be caused by medical conditions that decrease circulation, and most often occurs in the lower legs, which is the area of the body most affected by poor circulation.