In E. coli the main enzyme is DNA polymerase III and the enzyme that replaces the RNA primer with DNA is DNA polymerase I. When the RNA primer has been replaced with DNA, there is a gap between the two Okazaki fragments and this is sealed by DNA ligase.
Little Richard's Tutti Frutti (1955) was included in the National Recording Registry of the Library of Congress in 2010, which stated that his unique vocalizing over the irresistible beat announced a new era in music..
Tutti Frutti by Little Richard. Little Richard wrote this song in 1955 when he was working as a dishwasher at a Greyhound bus station in his hometown of Macon, Georgia. Explaining how he came up with the song, he told Rolling Stone: I couldn't talk back to my boss man.