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an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
In immunology, an antigen (Ag) is any structural substance that serves as a target for the receptors of an adaptive immune response, TCR or BCR or its secreted form antibody.ifferent antibodies have the potential to discriminate among specific epitopes present on the antigen surface. Hapten is a small molecule that changes the structure of an antigenic epitope. In order to induce an immune response, it has to be attached to a large carrier molecule such as a protein.