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This small nucleus contains almost half of all the brain neurons that use norepinephrine as a neurotransmitter. The locus coeruleus also projects its axons to those parts of the brain that may be associated with panic disorders (the amygdala, hippocampus, septum, cortex, brainstem, reticular formation, etc). Stimulating an animal's locus coeruleus, like stimulating its amygdala, produces anxiety behaviours.
Some examples of hormones affecting the brain include: 1  Adrenaline/Epinephrine Adrenaline is one of the most common causes of anxiety symptoms. 2  Your body releases it when your fight or flight system is active, and it causes the increase in heart rate, muscle tension, and more.