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Best Answer: That DNA is antiparallel means that the two strands of DNA have opposite chemical polarity, or, stated another way, their sugar-phosphate backbones run in opposite directions.
Each strand of DNA has a beginning and an end, called 5â (five prime) and 3â (three prime) respectively. The two strands run in the opposite direction (antiparallel) to each other so that one runs 5â to 3â and one runs 3â to 5â, they are called the sense strand and the antisense strand, respectively.