DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE IS NOT RECOMMENDED FOR CHILDREN UNDER 2 YEARS OF AGE. OVERDOSAGE MAY RESULT IN SEVERE RESPIRATORY DEPRESSION AND COMA, POSSIBLY LEADING TO PERMANENT BRAIN DAMAGE OR DEATH (See OVERDOSAGE).
Get moving. Often numbness in the feet or toes occurs when you have been sitting or standing in one place for a long time. The best way to get rid of this kind of numbness is to stimulate circulation in the foot by moving around. Try going for a short walk, or even just moving your foot around while you sit.
Direct compression of the nerves of the foot by too-tight or poorly fitting footwear is the most common cause of paresthesia, or numbness, of the toes, according to MediceneNet. Compression of blood vessels also might cause pain or tingling in the toe. A radiculopathy, or pinched nerve in the spine, can cause numbness of the foot by irritating the nerves in the lower back. Peripheral vascular disease also might cause numbness in the extremities, including the toes, according to MedicineNet.