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In some cases, a tissue type test may be done to see whether a person has a chance for developing certain diseases that cause the body to attack its own cells, such as autoimmune diseases. A special pattern of antigens (called tissue type) is present on each person's cells and tissues.
Many scientific journals require researchers who report results based on cell line experiments to use DNA profiling to establish the identity of the used cells. The new findings show that proper identification of a cell line also requires that the DNA profile matches the tissue of origin. This is essential if one wants to claim that the cells, and thereby the research results, are true representatives of the original tumor.