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Eczema is a disease in a form of dermatitis,or inflammation of the epidermis. In rare cases someone vaccinated against smallpox can develop eczema vaccinatum, which can cause organ failure. Ordinary eczema is not deadly.
Eczema herpaticum is caused by the same virus as the cold sore, herpes simplex. However, for a person with eczema the herpes virus can spread across the skin, and not be confined to the mouth and lips. In very severe and rare cases it can be fatal.