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Orchitis (or-KIE-tis) is an inflammation of one or both testicles. It is usually caused by a bacterial infection or by the mumps virus. Bacterial orchitis can be caused by sexually transmitted infections (STIs), particularly gonorrhea or chlamydia. Bacterial orchitis often results from epididymitis, an inflammation of the coiled tube (epididymis) at the back of the testicle that stores and carries sperm. In that case, it's called epididymo-orchitis.
Orchitis is a complication that occurs in up to 20% of postpubertal males, but sterility rarely occurs. The onset of orchitis may occur prior to or in the absence of parotitis. Females may experience oophoritis and/or mastitis with mumps infection.