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Thick blood is caused by a variety of conditions, such as heavy proteins in the blood, too much blood in circulation or a blood clot system imbalance, according to Southeastern Medical Oncology Center. Diseases such as cancer and lupus can also lead to thick blood. Continue Reading.
Hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy (HCM) is an inherited disease of your heart muscle, where the muscle wall of your heart becomes thickened. HCM is a genetic condition caused by a change or mutation in one or more genes and is passed on through families.f you have HCM, the muscular wall of your heart-the myocardium-becomes thickened, making the heart muscle stiff. This thickening makes it harder for your heart to pump blood out of your heart and around your body. How thick your muscle is, and how much of your muscle is affected, varies from one person to another.