Trenton, South Carolina. Trenton is a town in Edgefield County, South Carolina, United States. The population was 196 at the 2010 census,[3] down from 226 in 2000.
The severity of the Herx reaction is often an indicator of just how much toxicity there was in the body to begin with and is an indicator of the effectiveness of the treatment. It is actually a sign that the body is restoring itself to good health. There is differing data on the timing of a Herxheimer reaction. Some data indicates that it usually occurs between four and 24 hours from the onset of treatment. Others note that between Day 3 and Day 5 of a treatment program is often when the reaction is most noticeable.
The onset of analgesia after parenteral administration is about 5â10 minutes and after rectal administration, 15â30 minutes. The duration of analgesia is 3â4 hours for immediate-release tablets and 12 hours for extended-release tablets. It is also a minor metabolite of oxycodone, which is formed by CYP2D6 -mediated O-demethylation.