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The extra red blood cells make your blood thicker than normal. As a result, blood clots can form more easily. These clots can block blood flow through your arteries and veins, which can cause a heart attack or stroke. Thicker blood also doesn't flow as quickly to your body as normal blood.
Abnormal thickening of the uterine wall occurs when estrogen and progesterone hormonal levels are imbalanced: excess estrogen with low or no levels of progesterone. The imbalance can result from overproduction of estrogen, estrogen replacement therapy, ovarian tumors, tamoxifen use, obesity combined with diabetes, and menopause, notes Patient.co.uk.