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This condition can be caused by certain medications and by infections. In some cases, it is caused by a cancer or precancerous condition. Myelofibrosis, bone marrow scarring that can result from various hematologic cancers, typically leads to low blood counts. Pancytopenia can also be caused by aplastic anemia, a bone marrow failure disorder that affects blood cell production.
I am a MGUS patient that has recently been entered in the Natural History Study at NIH. I had all the work up and still have several questions. After reading a lot of info on this site, I seem more confused then ever about all my symptoms. I seem to have just as much or even more symptoms then most of the myeloma patients here. Which is why I want to ask more questions about my tests. I have always had elevated WBC without infections. Elevated alkaline phosphate with bone pain in upper arms, upper legs and back. Numbness, vibrations in leg. Low grade fevers and some night sweats.