The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated.
It is the interaction of two or more substances, resulting in chemical changes in them. Chemical reactions take place when some kind of energy is supplied to them. The supplied energy may be in the form of heat, light or mechanical shaking for proper contact between the reactant molecules or electricity.
Thermogenesis actually requires a great deal of energy, which is why cold blooded animals require far less energy to live. To keep temperatures stable, the body can generate heat in two ways. The first method is shivering, in which the body creates friction which generates warmth.