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This medication also is frequently used to administer general anesthesia for surgery. Propofol requires different patient monitoring during the procedure and, depending upon circumstances, may require anesthesia personnel, and so involve additional patient cost. Most of the time, the medicine is given through a vein.
Moderate sedation with medications like fentanyl and versed is universally used for colonoscopies. At my endoscopy center in Fullerton, we perform about 12,000 procedures a year, and 95% of them are done under moderate sedation. Patient satisfaction is high, and there have been no complaints of pain during these procedures.