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Lack of evidence: There is little evidence to suggest that low dose Seroquel is an effective treatment for insomnia. Despite the drugâs perception of being an effective treatment for insomnia, there is minimal evidence in support of these claims.
Quetiapine (SeroquelÂ®) is an orally administered atypical antipsychotic that is indicated for the treatment of schizophrenia and bipolar disorder, including bipolar depression. An extended-release (XR) formulation of quetiapine is also available.uetiapine (300 or 600 mg/d) was more effective than placebo for the treatment of episodes of acute depression in bipolar disorder. Lithium did not significantly differ from placebo on the main measures of efficacy. Both treatments were generally well tolerated.