In enzymes, some of these amino acids form a site in the structure that catalyzes the enzymatic reaction. This site, called the active site of the enzyme, has amino acids that bind specifically to the substrate molecule, also called a ligand (Fig. 2). In a similar manner, certain sites in cell receptor proteins bind to specific ligand molecules that the receptor recognizes.
When did France's second empire end? The Second Empire ended with the swift and catastrophic defeat of  France in the Franco-Prussian war of 1870. The war was engineered  by Bismarck with the idea that Germany â¦would be united.This  included the capture by the Prussians of the Napoleon III. Then the  proclamation at Versailles of the German Empire, the loss to France  of Alsace and Lorraine, and the proclamation of the Third Republic.
It was part of the general settlement made by the Congress of Vienna and can only be understood in relation to that conference. The participants were the same at both conferences, but the Second Peace of Paris was made after the settlement at Vienna. The Second Peace of Paris was also linked to negotiations leading to the Quadruple Alliance, and both agreements were signed on the same day.