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Thick blood is caused by a variety of conditions, such as heavy proteins in the blood, too much blood in circulation or a blood clot system imbalance, according to Southeastern Medical Oncology Center. Diseases such as cancer and lupus can also lead to thick blood. Continue Reading.
High levels of abnormal white blood cells can cause anemia, tiredness, weight loss, bone pain and frequent infections. Most seriously, people with thick blood -- whether from excessive blood cells or hypercoagulation -- are at high risk for clots that block or limit blood flow to vital organs.