Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
The default is for things to shrink when they freeze. This is because, normally, if you make something hotter, it vibrates more. When it vibrates more, it tends to take up more space, so it tends to expand. Ice is very unusual that, as it gets colder, although the particles are vibrating less, it expands. The reason for that is due to the strange shape of water.