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This condition can be caused by certain medications and by infections. In some cases, it is caused by a cancer or precancerous condition. Myelofibrosis, bone marrow scarring that can result from various hematologic cancers, typically leads to low blood counts. Pancytopenia can also be caused by aplastic anemia, a bone marrow failure disorder that affects blood cell production.
by Anne Harding. NEW YORK -- Physicians treating myelofibrosis patients with ruxolitinib (Jakafi) must pay careful attention to dosing during the first 3 months, given the risk of anemia and thrombocytopenia, according to leading experts on the medication speaking at a recent symposium here.