Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
Clearly, the molecular disorder in a gas will be greater than that in a liquid, so there must be an entropy increase upon vapourisation. Likewise, when a liquid freezes the mobile molecules of the liquid phase are forced to assume fixed positions in the solid phase. This will normally reduce the molecular disorder of the system, so there will usually be an entropy decrease that accompanies freezing.