MALIGNANCY. Low back pain at night that is not relieved by lying down may be caused by a tumor in the cauda equina (the roots of the spinal nerves controlling sensation in and movement of the legs), or a cancer that has spread to the spine from the prostate, breasts, or lungs. The pain is caused by irritation of a nerve root. 2  Sciatica is an example of radicular pain. 3  Referred. 4  The pain is perceived in the lower back but is caused by inflammation elsewhereâoften in the kidneys or lower abdomen.
While most moles donât turn into melanoma, researchers are unsure why some do. Like basal and squamous cell skin cancer, melanoma can be caused by UV rays. However, some melanomas can appear in body parts not exposed to sunlight. Both types of skin cancer occur when your skin cellsâ DNA has errors (or mutations). According to the Mayo Clinic, these errors cause skin cells to grow uncontrollably and form a mass of cancer cells.
Skin cancers are cancers that arise from the skin. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of skin cancers: basal-cell skin cancer, squamous-cell skin cancer and melanoma. The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer. Basal-cell cancer grows slowly and can damage the tissue around it but is unlikely to spread to distant areas or result