The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
Born: c. 1595 Virginia Died: 1617 Gravesend, Kent, England. Native American princess. Pocahontas was the daughter of a Native American chief in Virginia at the time when the British came to settle in the area. Her marriage to an English settler brought eight years of peace between the Indians and the British.ocahontas's real name was Matoaka. As a child, she was also called Pocahontas, meaning playful one, and the name stuck. Her father was Powhatan (c. 1550â1618), the chief of a group of tribes that bore his name and spoke the Native American Algonquian language.