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Site of RVD channels: the cytoplasmic droplets. The cytoplasmic droplet is one site of osmolytes channels involved in RVD. In the mouse, K + channels, Cl â channels and K + âCl â cotransporters, and in man K + and Cl â channels, have been located there, at the neck and along the midpiece.ite of RVD channels: the cytoplasmic droplets. The cytoplasmic droplet is one site of osmolytes channels involved in RVD. In the mouse, K + channels, Cl â channels and K + âCl â cotransporters, and in man K + and Cl â channels, have been located there, at the neck and along the midpiece.
Vaccinia virus (VV) is a member of the Poxviridae, a group of large, double-stranded DNA viruses that replicate in the cytoplasm of the host cell (20). Poxvirus infection induces extensive changes to cell metabolism and structure (8) which are collectively termed the viral cytopathic effect (CPE).n both cases, cell movement was not induced, suggesting that virus protein synthesis was needed within the infected cell. Consistent with this, infections performed in the presence of 300 Î¼g of cycloheximide per ml induced no cell movement (Fig.