Organomegaly involves the enlargement of body organs. Many different factors may cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement â called cardiomegaly, hepatomegaly, and splenomegaly, respectively â represent three examples of abnormal organ enlargement.
Thumb pain can result from damage or injury to any of the structures in your thumb, including bones, joints, tendons, nerves, muscles, blood vessels, connective tissue, skin or fingernails. The symptoms may be constant or they may vary, and they may improve or worsen with movement.
Not all pain in the wrist or hand is caused by carpal tunnel syndrome. There are many other conditions with similar symptoms, such as: 1  An injury to the muscles, ligaments, tendons, or bones. 2  Nerve problems in the fingers, elbow, or neck.  Arthritis in the thumb joint or wrist.