Trulicity 1.5 mg solution for injection. Each pre-filled syringe contains 1.5 mg of dulaglutide* in 0.5 ml solution. *Produced in CHO cells by recombinant DNA technology. For the full list of excipients, see section 6.1.
Frostbite is the medical condition in which localized damage is caused to skin and other tissues due to freezing. Frostbite is most likely to happen in body parts farthest from the heart and those with large exposed areas.The initial stages of frostbite are sometimes called frostnip.he several classifications for tissue damage caused by extreme cold include: 1  Frostnip is a superficial cooling of tissues without cellular destruction. 2  Chilblains are superficial ulcers of the skin that occur when a predisposed individual is repeatedly exposed to cold.
Especially severe frostbite can cause death of the injured tissues and gangrene. Mild frostbite usually appears as a shallow, blanched wheal on the nose, ears, fingers, or toes. After rewarming, the area is slightly reddened for several hours and then resumes a normal appearance. If the frostbite is more severe, deeper tissues are affected and the area appears waxy and feels doughlike to the touch.