For example, Microsoft Office is a COTS product that is a packaged software solution for businesses. COTS products are designed to be implemented easily into existing systems without the need for customization.
Acral Lentiginous Melanoma Treatment. Acral lentiginous melanoma is a form of skin cancer that occurs on areas of the body where hair does not grow. It is most often seen on the palms of the hands, the soles of the feet, or in the mucus in a personâs mouth.
The changes, bearing the hallmark of UVA damage, were found in the deep basal keratinocyte cell layer. Treatment with hyaluronic acid elicited a cutaneous reepithelization, laminin being present in basal keratinocyte cytoplasm and discontinuous in the basement membrane (Fig. Importantly, smaller atypical melanocytes of lentigo maligna may be partially obscured by surrounding enlarged pigmented basal keratinocytes.