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White blood cells known as lymphocytes arise from by mitosis of stem cells in the bone marrow. Some lymphocytes migrate to the thymus and become T cells that circulate in the blood and are associated with the lymph nodes and spleen.
Lymphopoiesis (lÄ­m'fÅ-poi-Ä'sÄ­s) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC).It is more formally known as lymphoid hematopoiesis. cells are formed in bone marrow then migrate to the cortex of the thymus to undergo maturation in an antigen-free environment for about one week where a mere 2-4% of the T cells succeed. The remaining 96-98% of T cells die by apoptosis and are phagocytosed by macrophages in the thymus.