Bake the fish in the middle of the oven; broil it with its surface 5 inches below the broiler at the top of the oven. Bake the tilapia for about 8 to 10 minutes or broil it for about 5 to 8 minutes, just until its flesh is flaky and opaque all the way through. Fish should be cooked to an internal temperature of 145 F, as measured with an instant-read food thermometer, per the recommendation of the U.S. Department of Agriculture. If you know 12 to 48 hours ahead that you'll be cooking frozen tilapia filets, just move them from the freezer to the refrigerator to thaw.
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