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The imaging drum is charged with a high negative voltage (between -500 and -1,000 VDC ) with a primary charge roller. In older laser printers, a corona wire applied the high negative voltage instead of a primary charge roller.
In immunohistochemistry tests, cells from the blood or bone marrow samples are also treated with special antibodies. But instead of using a laser and computer, the sample is treated so that certain types of cells change color when seen under a microscope. lumbar puncture is not often used to test for AML, unless the patient is having symptoms that could be caused by leukemia cells spreading into the brain and spinal cord. For this test, the patient may lie on his side or sit up. The doctor first numbs an area of skin on the lower part of the back over the spine.