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Large red blood cells aka Macrocytosis is a common effect caused by Vitamin B12/Folate deficiency anemia.Common causes are a vegan diet, because Vitamin B12 comes from foods from animal origin.arge red blood cells aka Macrocytosis is a common effect caused by Vitamin B12/Folate deficiency anemia.
Macrocytosis is a descriptive term for red blood cell (RBC) size larger than the normal range. It may be caused by abnormalities of RBC production in the bone marrow, altered RBC membrane composition, or an increase in the percentage of reticulocytes, which are larger than mature RBCs. This topic discusses causes of macrocytosis and macrocytic anemia. Additional topics discuss the following: