Figure 3: Vasodilation produced by the direct effects of caffeine on the VSMC. Caffeine inhibits the voltage-dependent Ca2+ channels and the entrance of calcium to the cytoplasm. In addition, it inhibits the IP3 receptor and increases the ânon-contractile Ca2+.
Instructions. 1. Fill the bottom of the pan with a layer of water. 2. Add the vinegar. 3. Bring the pan to the boil. It should be looking a bit cleaner already. 4. Remove the pan from the heat and add the baking soda. Expect fizz! 5.Empty the pan and scour as normal; if necessary add an extra bit of dry baking soda.6. If there are any super stubborn marks that don't come off with scouring, make a paste of baking soda and a couple of drops of water.. Remove the pan from the heat and add the baking soda. Expect fizz! 5. Empty the pan and scour as normal; if necessary add an extra bit of dry baking soda. 6. If there are any super stubborn marks that don't come off with scouring, make a paste of baking soda and a couple of drops of water.
2. Dip a cotton ball in rubbing alcohol or acetone, such as fingernail polish remover. Scrub the stain with the cotton ball, moistening it with more alcohol or acetone as necessary. Alcohol and acetone may remove the stain completely, or they may lighten the mark considerably.nce a stray mark makes its way onto an appliance, it becomes a challenge to remove the mark without damaging the finish. Appliances, whether it's a refrigerator, stove or toaster, are made of different materials that don't withstand the same cleaning methods.