Autoimmune diseases usually do not usually have a simple, single cause. There are usually two major factors that are involved in causing them: genetics and environment. Genetics - Even with a genetic connection to autoimmune disease, there is no guarantee that you will develop an autoimmune disease. Something must turn on your immune system to trigger an autoimmune response. Environment - Environmental factors make up more than half the risk of developing an autoimmune disease.
A: Advil (ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). Advil can be used for pain and inflammation. Motrin (ibuprofen) is the same medication as Advil; they are both ibuprofen. They are just made by different companies.
Hence during any infection it is common for the lymph nodes to increase in size and also become a bit tender (pain on application of pressure). You can take anti inflammatory medications like Advil or motrin for a few days, which will reduce the inflammation and the pain.