The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
Born about 1596, she was named. Amonute. She was also given a personal secret. name, Matoaka, which she never told anyone until. years later when she went to live with the English. Pocahontas, a nickname meaning âplayful one,â was. given to her by her father. Pocahontas enjoyed playing and turning cartwheels. Powhatan had numerous wives from different villages, and Pocahontas had a large. number of half-brothers and half-sisters. As a young child, Pocahontas lived in her motherâs village. She wore deerskin clothing. and slept in a yehakin, a Powhatan house made of bent saplings and covered with reeds. or bark. The house was high with a rounded ceiling. There was a central fire, which was. kept burning all the time.