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What can ibuprofen be used for? Ibuprofen is effective in the relief of inflammation and/or pain associated with headaches, backache, muscular aches, arthritic pain, rheumatic pain, neuralgia, some cold and flu symptoms, period pain, dental pain, and it reduces fever.buprofen is an NSAID (non-steroidal anti-inflammatory drug) - the term used for a whole group of medicines that have pain-relieving (analgesic), anti-inflammatory and fever-relieving (antipyretic) properties.