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Freebase(0.00 / 0 votes)Rate this definition: Imidacloprid is a systemic insecticide which acts as an insect neurotoxin and belongs to a class of chemicals called the neonicotinoids which act on the central nervous system of insects with much lower toxicity to mammals.
Imidacloprid, the medication which you find in the brand name Advantage is safe for puppies older than 7 weeks. Imidacloprid and Permethrin is available as K9 Advantage. It is a spot-on treatment you apply every month. Imidacloprid will kill fleas, but not ticks.