The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
Prior to the 18th century, most of Georgia was home to Native Americans known as the Creek Indians. The name Creek came from the shortening of Ocheese Creek Indians-a name given by the English to the native people along the Ocheese Creek (or the Ocmulgee River). The Creek Indian Lodge in the Children's Garden is an example of a wattle and daub house.