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When someone gets HIV, the body's immune system makes antibodies to try to fight the infection. Most HIV tests available today test for HIV antibodies. If HIV antibodies are present, it means that a person is infected with HIV. One type of HIV test detects the virus itself. This is called an RNA test. RNA testing is more expensive and much less common than antibody tests.
A human immunodeficiency virus (HIV) test detects antibodies to HIV or the genetic material (DNA or RNA) of HIV in the blood or another type of sample. This determines whether an HIV infection is present (HIV-positive).hese tests include: 1  Enzyme-linked immunosorbent assay (ELISA) . 2  This test is usually the first one used to detect infection with HIV. 3  If antibodies to HIV are present (positive), the test is usually repeated to confirm the diagnosis. 4  If ELISA is negative, other tests are not usually needed.