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Site of RVD channels: the cytoplasmic droplets. The cytoplasmic droplet is one site of osmolytes channels involved in RVD. In the mouse, K + channels, Cl â channels and K + âCl â cotransporters, and in man K + and Cl â channels, have been located there, at the neck and along the midpiece.ite of RVD channels: the cytoplasmic droplets. The cytoplasmic droplet is one site of osmolytes channels involved in RVD. In the mouse, K + channels, Cl â channels and K + âCl â cotransporters, and in man K + and Cl â channels, have been located there, at the neck and along the midpiece.
General Discussion. Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder characterized by the gradual onset of muscle weakness, especially of the pelvic and thigh muscles. Approximately 60 percent of LEMS cases are associated with a small cell lung cancer (SCLC), and the onset of LEMS symptoms often precedes the detection of the cancer.