Organomegaly involves the enlargement of body organs. Many different factors may cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement â called cardiomegaly, hepatomegaly, and splenomegaly, respectively â represent three examples of abnormal organ enlargement.
Thumb pain can result from damage or injury to any of the structures in your thumb, including bones, joints, tendons, nerves, muscles, blood vessels, connective tissue, skin or fingernails. The symptoms may be constant or they may vary, and they may improve or worsen with movement.
The pain and swelling in the hand joints and wrists caused by arthritis also can be responsible. For example, pain at the base of the thumb is commonly caused by osteoarthritis. Tendonitis â an inflammation of the tendons that connect muscles to bones â can cause pain, swelling, and impaired use of the hand or wrist.he pain and swelling in the hand joints and wrists caused by arthritis also can be responsible. For example, pain at the base of the thumb is commonly caused by osteoarthritis. Tendonitis â an inflammation of the tendons that connect muscles to bones â can cause pain, swelling, and impaired use of the hand or wrist.