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A child with Kohlerâs disease may present similarly to a child with a foot injury. An examination will reveal pain and tenderness over the dorsomedial midfoot, with or without local skin changes. Affected children typically walk with a limp or antalgic gait, with weight bearing on the lateral side of the foot.
Hepatomegaly in neonates and children. 1  Infections: TORCH* infections, hepatitis viruses and EBV and malaria. 2  Metabolic: galactosaemia, lipid storage disorders - eg, Gaucher's disease. 3  Neoplastic: leukaemia, lymphoma and hepatoblastoma. 4  Haematological: sickle cell anaemia and thalassaemia.