The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration.
However, there has been research in this area. In germany, frankincense (boswellia serrata) is aparently considered a standard treatment for cancer in brain because it is one of the few substances believed to cross the BBB. Wormwood (Artemisia absinthium) is another possibility.owever, there has been research in this area. In germany, frankincense (boswellia serrata) is aparently considered a standard treatment for cancer in brain because it is one of the few substances believed to cross the BBB. Wormwood (Artemisia absinthium) is another possibility.
Immaturity of the blood-brain barrier probably plays a role in kernicterus. Infusion of bilirubin in experimental animals, after opening of the barrier by injecting hypertonic solutions, causes bilirubin staining. Bilirubin encephalopathy affects parts of the brain that are also involved in perinatal HIE. According to one school of thought, kernicterus is simply due to leakage of bilirubin in areas where the blood-brain barrier has been damaged by HIE. Babies with bilirubin encephalopathy are lethargic, hypotonic or hypertonic, and have a high pitched cry, opisthotonus, seizures, and may die if bilirubin is not lowered.