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Basal cell carcinoma. This is not only the most common type of skin cancer, but the most common type of cancer in humans. About 8 out of 10 skin cancers are basal cell carcinomas (also called basal cell cancers).When seen under a microscope, the cells in these cancers look like cells in the lowest layer of the epidermis, called the basal cell layer. These cancers usually develop on sun-exposed areas, especially the head and neck.bout 8 out of 10 skin cancers are basal cell carcinomas (also called basal cell cancers). When seen under a microscope, the cells in these cancers look like cells in the lowest layer of the epidermis, called the basal cell layer. These cancers usually develop on sun-exposed areas, especially the head and neck.
Practice Essentials. Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, after basal cell carcinomas. Although cSCC is not often fatal, many of these lesions occur in the head and neck region, where surgery for advanced-stage disease can be disfiguring.y convention, the term head-and-neck squamous cell carcinoma typically refers to SCC of the mucosal linings of the head and neck rather than to cSCC. Although conjunctival SCC also involves mucosa rather than skin, it is briefly considered in the Clinical Presentation and Treatment sections.