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Print This Page. Inflammation of an outgrowth to the tarsal navicular bone is called Kohler disease. This condition occurs most commonly in children two to nine years of age. Children with Kohler disease present with unilateral foot pain and tenderness to light pressure/touch over the tarsal navicular bone. For more information or to schedule an appointment, call 314.454.5437 or 800.678.5437 or email us.
Koplik spots (small bluish yellow spots) occur in the mouth on buccal mucosa. The maculopapular rash appears first on the head, and then progressively spreads over the chest, trunk, and then limbs, eventually covering the entire body. Infection of the measles virus occurs through the respiratory tract. The receptor for the measles virus is the human complement regulatory cofactor protein CD46.