The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
Tribal Origin: Shoshonean Tribe. Native Name: Ute, means 'people on the bank'. Ute Tribes: Capote, Cumumba, Kapote, Moache, Moanumts, Pah Vant, Parianuche, San Pitch, Sheberetch, Taviwach, Timanogots, Tumpanawach, Uinta, Uncompahgre, White River, Weeminuche and Yamperika.ribal Origin: Shoshonean Tribe. Native Name: Ute, means 'people on the bank'. Ute Tribes: Capote, Cumumba, Kapote, Moache, Moanumts, Pah Vant, Parianuche, San Pitch, Sheberetch, Taviwach, Timanogots, Tumpanawach, Uinta, Uncompahgre, White River, Weeminuche and Yamperika.