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7 Hpw long would it take for (1) 81mg of aspirin to be completely out of your system...On for about 1 year. Dr. Venkata Chilakapati Dr. Chilakapati. Aspirin: For small dose of Aspirin elimination half life is 2 to 4.5 hours. So within 24 hours it will be completely eliminated from the body.
Your Privacy Rights | About Us. Fifty-one volunteers took aspirin for 14 days and then stopped. Blood samples revealed that their platelets began clotting normally after 4 days. Previously, advice on stopping ranged from 3 days to 2 weeks, says study author Ronan A. Cahill, MD. Doctors recommend resuming aspirin a day or two after surgery.