renin-angiotensin-aldosterone system the regulation of sodium balance, fluid volume, and blood pressure by secretion of renin in response to reduced perfusion of the kidney.
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Causes of Crepitus or Joint Popping. Often, crepitus is harmless. It happens when air seeps into the soft tissues around the joint (such as the kneecap). When you bend the joint, the air bubbles burst, and you hear a cracking sound. While most crepitus is harmless, some forms of crepitus signal a problem.