MALIGNANCY. Low back pain at night that is not relieved by lying down may be caused by a tumor in the cauda equina (the roots of the spinal nerves controlling sensation in and movement of the legs), or a cancer that has spread to the spine from the prostate, breasts, or lungs. The pain is caused by irritation of a nerve root. 2  Sciatica is an example of radicular pain. 3  Referred. 4  The pain is perceived in the lower back but is caused by inflammation elsewhereâoften in the kidneys or lower abdomen.
While most moles donât turn into melanoma, researchers are unsure why some do. Like basal and squamous cell skin cancer, melanoma can be caused by UV rays. However, some melanomas can appear in body parts not exposed to sunlight. Both types of skin cancer occur when your skin cellsâ DNA has errors (or mutations). According to the Mayo Clinic, these errors cause skin cells to grow uncontrollably and form a mass of cancer cells.
Although, the word âcancerâ elicits a great deal of fear and anxiety, all forms of cancer are different. The three main types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Nonmelanoma skin cancer (basal cell carcinoma or squamous cell carcinoma) are the most common. These lesions are often red, scaly or waxy-looking and can be painful, bleed and increase in size.