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The dose (volume of injection in mL) per month = patient weight (kg) x 15 mg per kg Ã· 100 mg per mL of Synagis. Injection volumes over 1 mL should be. given as a divided dose. â¢ Synagis is supplied as a single-dose vial and does not contain preservatives.
A weight-based nomogram has been used to determine adequate dosing, using heparin at 80 mg/kg for the bolus and 18 mg/kg/hr for the infusion. A short course of heparin is followed by a longer course of oral anticoagulant, warfarin sodium.