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Manganese is a part of many enzyme systems, including the enzymes involved in blood sugar control, energy metabolism, and thyroid hormone function. Manganese also participates in the antioxidant enzyme, superoxide dismutase, or SOD.
In biology, manganese(II) ions function as cofactors for a large variety of enzymes with many functions. Manganese enzymes are particularly essential in detoxification of superoxide free radicals in organisms that must deal with elemental oxygen.t is not found as a free element in nature; it is often found in combination with iron, and in many minerals. Manganese is a metal with important industrial metal alloy uses, particularly in stainless steels.