Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
Symptoms of gout often affect the big toe, in which case it may be referred to as podagra. The inflammation is a result of excess uric acid building up in the toe joint. Inflammation that is caused by gout is often seen in people who are overweight, diabetic, have kidney disease, or that are taking certain medications.