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Causes of sepsis. Sepsis can be triggered by an infection in any part of the body. The most common sites of infection leading to sepsis are the lungs, urinary tract, tummy (abdomen) and pelvis. Sepsis may develop when you're already in hospital. For example, you're more likely to develop sepsis if:
Any type of infection that is anywhere in your body can cause sepsis, including infections of the skin, lungs (such as pneumonia), urinary tract, abdomen (such as appendicitis), or other part of the body. An infection occurs when germs enter a personâs body and multiply, causing illness, and organ and tissue damage.ee Also â Sepsis Fact Sheets. Sepsis is the bodyâs overwhelming and life-threatening response to an infection which can lead to tissue damage, organ failure, and death.