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Neurons that produce GABA as their output are called GABAergic neurons, and have chiefly inhibitory action at receptors in the adult vertebrate.Medium Spiny Cells are a typical example of inhibitory CNS GABAergic cells.rugs that act as allosteric modulators of GABA receptors (known as GABA analogues or GABAergic drugs) or increase the available amount of GABA typically have relaxing, anti-anxiety, and anti-convulsive effects.
GABAergic control of substantia nigra dopaminergic. neurons. James M. Tepper and Christian R. Lee. Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University Avenue, Newark, NJ 07102, USA. Abstract: At least 70% of the afferents to substantia nigra dopaminergic neurons are GABAergic. The vast majority of these arise from the neostriatum, the external globus pallidus and the substantia nigra pars reticulata. Nigral dopaminergic neurons express both GABA A and GABA B receptors, and are inhibited by local application of GABA A or GABA B agonists in vivo and in vitro.