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1 People often experience an upset stomach, diarrhea (possibly bloody), abdominal pain and painful swallowing when using aspartame as a sweetener.  Skin and Allergies. Hives and intense itching, lip or mouth swelling and worsening of asthma all can occur due to aspartame.
Aspartame is linked to diabetes, auto-immune disorders, depression (which can cause you to eat more â once again), birth defects, and several forms of cancer. âErythritolâ found in Vitamin Water Zero is a sugar alcohol the body does not easily digest and is linked to diarrhea, headache and other intestinal disorders.