Grasshopper ketone; (?)-Grasshopper ketone; CHEMBL456946; CHEMBL2392400; (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-9-apo-beta-caroten-9-one; 4-[(2R)-2alpha,4beta-Dihydroxy-2,6,6-trimethylcyclohexylidene]-3-butene-2-one More... Molecular Formula: C 13 H 20 O 3: Molecular Weight: 224.3 g/mol: InChI Key: QMXLZUOHZGYGDY-JBGXHEPSSA-N
Repatha (evolocumab) is a monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9) indicated for the treatment of patients with heterozygous familial hypercholesterolemia (HeFH), homozygous familial hypercholesterolemia (HoFH), or patients with atherosclerotic heart disease who require additional lowering of ...
Background/Purpose: Biologics including rituximab, abatacept and belimumab increase the risk of infection in patients. Denosumab, a RANK-ligand inhibitor used in the treatment of osteoporosis may theoretically make patients more susceptible to infections.