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The list of signs and symptoms mentioned in various sources for Hyponatremia includes the 10 symptoms listed below: 1  Low blood sodium level. 2  Nausea - severe hyponatremia. 3  Vomiting - severe hyponatremia.  Headache - severe hyponatremia.
Because the brain is very sensitive to sodium levels, low sodium causes symptoms including confusion and lethargy. The patient may feel nauseated, and experience muscle twitching, which can progress to seizures. Eventually, severe hyponatremia can lead to coma and death.