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Causes of sepsis. Sepsis can be triggered by an infection in any part of the body. The most common sites of infection leading to sepsis are the lungs, urinary tract, tummy (abdomen) and pelvis. Sepsis may develop when you're already in hospital. For example, you're more likely to develop sepsis if:
Sepsis is a severe illness caused by infection of the bloodstream and the bodyâs resulting inflammatory response. Bacteria in the bloodstream (bacteremia) is the most common cause of sepsis; but viruses, parasites, and fungi in the blood may also cause sepsis.Sepsis usually results from the spread of an infection from a localized site in the body such as the lungs, skin, abdomen, central nervous system, or urinary tract.acteria in the bloodstream (bacteremia) is the most common cause of sepsis; but viruses, parasites, and fungi in the blood may also cause sepsis. Sepsis usually results from the spread of an infection from a localized site in the body such as the lungs, skin, abdomen, central nervous system, or urinary tract.