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BUT Wellbutrin is also known to increase anxiety in certain patients. It's not an SSRI medication like most anti-depressants prescribed today (SSRIs are serotonin related) such as Paxil, Prozac, Zoloft and other popular SSRIs. Wellbutrin deals with dopamine receptors in our brain.
Actually, Wellbutrin is a stimulating anti-depressant, and although it certainly can make some people tired, it is more common that it will do the opposite. Anxiety and insomnia are very common. I take my first Wellbutrin SR dose in the morning with the Prozac and Focalin. It does not cause me any issues. I don't know about taking Requip with Wellbutrin......Wellbutrin is such a touchy drug.... I'd check with your doc about the side effects....