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1 People often experience an upset stomach, diarrhea (possibly bloody), abdominal pain and painful swallowing when using aspartame as a sweetener.  Skin and Allergies. Hives and intense itching, lip or mouth swelling and worsening of asthma all can occur due to aspartame.
If you have chronic pain and are using aspartame, it may do you well to learn about this toxic substance, which causes problems ranging from fibromyalgia to epilepsy to Alzheimer's disease.