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1 People often experience an upset stomach, diarrhea (possibly bloody), abdominal pain and painful swallowing when using aspartame as a sweetener.  Skin and Allergies. Hives and intense itching, lip or mouth swelling and worsening of asthma all can occur due to aspartame.
Before you resort to taking medications or having surgery, try giving up the aspartame for a week or so. Use Stevia, or even real sugar and see what happens. Aspartame irritates the bladder, causing it to spasm and making you feel like you have to urinate. The spasms also make you urinate more frequently. As little as one diet soda or packet of aspartame can cause issues in some people. My mom has had an escalating problem for years.