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1 When blood clots occur in a vein, symptoms may include. 2  pain, 3  swelling, 4  warmth, and. 5  redness. 6  If a forms in a vein in a leg or arm breaks; breaks off and travels to the lung a pulmonary embolus can occur. 7  Symptoms of pulmonary embolism are chest pain and shortness of breath.
Sometimes the first and only sign of a blood clot in one leg is the swelling. Other signs might include a lack of feeling in the leg, or pain in the affected area, or even a tingling, numbing sensation. The leg might also feel hotter or colder than the other leg does.