Training presents a prime opportunity to expand the knowledge base of all employees, but many employers find the development opportunities expensive. Employees also miss out on work time while attending training sessions, which may delay the completion of projects.
Cystic fibrosis is an autosomal recessive disease caused by defects in the CFTR gene, which encodes for a protein that functions as a chloride channel, and also regulates the flow of other ions across the apical surface of epithelial cells.
Nearly two thousand cystic fibrosis-causing mutations have been described. The most common mutation, Î´F508 results from a deletion (Î´) of three nucleotides which results in a loss of the amino acid phenylalanine (F) at the 508th position on the protein.