1 For example, if you sell a product for $25, and it costs $20 to make, the gross profit margin is 20% ($5 divided by $25). 2  Net Profit Margin: This is often the equation used to determine an entire organizationâs profit margin.
Avascular necrosis (AVN), also called osteonecrosis, aseptic necrosis, or ischemic bone necrosis, is a condition that occurs when there is loss of blood to the bone. Because bone is living tissue that requires blood, an interruption to the blood supply causes bone to die. If not stopped, this process eventually causes the bone to collapse.
What is avascular necrosis? Avascular necrosis (AVN) is a condition that occurs when bone tissue dies because of too little blood supply. With avascular necrosis, the bone eventually collapses after tiny breaks (or microfractures) occur. Commonly, the condition affects the thigh bone (femur) in the hip area, but it can affect other bones in the body, including the jaw, hand/wrist, elbow, shoulder, knee, and foot locations.