1 For example, if you sell a product for $25, and it costs $20 to make, the gross profit margin is 20% ($5 divided by $25). 2  Net Profit Margin: This is often the equation used to determine an entire organizationâs profit margin.
Avascular necrosis (AVN), also called osteonecrosis, aseptic necrosis, or ischemic bone necrosis, is a condition that occurs when there is loss of blood to the bone. Because bone is living tissue that requires blood, an interruption to the blood supply causes bone to die. If not stopped, this process eventually causes the bone to collapse.
Avascular necrosis (AVN) is a disease that may affect several different bones as a result of temporary or. permanent loss of the blood supply to these bones. The femoral head is most commonly affected by this. disease. Usually, the patients are in their third, fourth or fifth decade of life at the time of diagnose. Initially, patients are asymptomatic, but, in time, AVN leads to joint destruction, requiring surgical. treatment and, in latter stages, total hip replacement.