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Scarred glomeruli in the kidney of a person with diabetic nephropathy. [edit on Wikidata] Diabetic nephropathy (or diabetic kidney disease) is a progressive kidney disease caused by damage to the capillaries in the kidneys' glomeruli. It is characterized by nephrotic syndrome and diffuse scarring of the glomeruli.
Diabetic nephropathy is the leading cause of kidney disease in patients starting renal replacement therapy and affects â¼40% of type 1 and type 2 diabetic patients. It increases the risk of death, mainly from cardiovascular causes, and is defined by increased urinary albumin excretion (UAE) in the absence of other renal diseases.