Fatigue may be related to: 1  Use of alcohol or drugs. 2  Excess physical activity. 3  Jet lag.  Lack of physical 1  activity. Lack of sleep.  Medications, such as antihistamines, cough 1  medicines. Unhealthy eating habits.
Difference between a Regulation, Directive and Decision. Regulations have binding legal force throughout every Member State and enter into force on a set date in all the Member States.
Directive (European Union) A directive is a legal act of the European Union, which requires member states to achieve a particular result without dictating the means of achieving that result. It can be distinguished from regulations which are self-executing and do not require any implementing measures.