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The aging process is associated with changes in the composition and function of the immune system and these changes may occur at an accelerated rate in men as compared to women. Moreover, after the age of menopause, the incidence of chronic inflammatory disease in women approaches or exceeds that observed in males.he mechanisms responsible for sex-specific differences in the immune response are complex and likely involve effects of the sex hormones on the immune system, genetic factors, and gender-specific behaviors and exposures.
Vasculitis (CNS) Vasculitis of the central nervous system (CNS) is an autoimmune disorder in which the body mistakes its own blood vessels that supply the brain and spinal cord as a foreign substance and launches antibodies to attack them. It is not known what causes this faulty immune response. Inflammation of the blood vessels prevents blood from flowing to parts of the brain and spinal cord, which can result in damage to the CNS, including: decreased function due to decreased blood flow (ischemia),