Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
1) Gout. Gout is a common cause of big toe joint pain. The classic symptoms are sudden, intense pain, inflammation, redness, heat and tenderness. Gout most commonly affects the big toe, known as podagra, but can affect any of the other toes.