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DNA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule. Thus, it is a POLAR molecule which allows it to interact in an aqueous environment.NA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule.
Best Answer: Histones carry a positive charge. This is because they need to interact with DNA, which is negatively charged. According to the link below: Acetylation is an important element in this histone-modification language. The histone tails contain many lysine amino acids, which interact favorably with the many negative charges on the DNA backbone.