Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
Knee Sprain. One of the most common causes of knee swelling is a ligament sprain, or excessive straining of the knee. During this time, the knee ligament could be torn or stretched, resulting in pain, swelling, bruising, and limited ability to move the knee.