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sepsis. the presence in the blood or other tissues of pathogenic microorganisms or their toxins; the condition associated with such presence. See also toxemia, bacteremia.. Sepsis is a very serious medical condition. It is characterized by an inflammatory state of the entire body, caused by an infection. The infection may be viral, bacterial or another, and sometimes is caused by specific bacterial toxins, in the blood or tissues. 1  Facebook.
Topic Overview. Sepsis is an extreme immune system response to an infection that has spread throughout the blood and tissues. Severe sepsis, also called septic shock, often causes extremely low blood pressure, which limits blood flow to the body and can result in organ failure and death.