Fatigue may be related to: 1  Use of alcohol or drugs. 2  Excess physical activity. 3  Jet lag.  Lack of physical 1  activity. Lack of sleep.  Medications, such as antihistamines, cough 1  medicines. Unhealthy eating habits.
Difference between a Regulation, Directive and Decision. Regulations have binding legal force throughout every Member State and enter into force on a set date in all the Member States.
Definition of directive. : something that serves to direct, guide, and usually impel toward an action or goal; especially, government : an authoritative order or instrument issued by a high-level body or official a presidential directive.