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Limb-girdle muscular dystrophy is a term for a group of diseases that cause weakness and wasting of the muscles in the arms and legs. The muscles most affected are those closest to the body (proximal muscles), specifically the muscles of the shoulders, upper arms, pelvic area, and thighs.
Neuromuscular disorder is a broad term that encompasses many different syndromes and diseases that either directly or indirectly impairs the function of the skeletal muscles, the muscles that move the limbs and trunk.he term Limb Girdle Muscular Dystrophy (LGMD) represents a family of genetic muscle disorders that produce weakness and muscle wasting restricted to the limbs. The pattern of weakness tends to be more proximal than distal.