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The four most common teratogens are  tobacco, alcohol, medications and illegal drugs. Teratogens are substances that could harm a developing fetus by affecting growth and causing birth defects or death.
1 Medulloblastoma is the most common malignant brain tumor of childhood, and it accounts for about 20 percent of all childhood brain tumors.2  Between 250 and 500 children are found to have medulloblastoma each year in the United States. Medulloblastoma is the most common malignant brain tumor of childhood, and it accounts for about 20 percent of all childhood brain tumors.