Grasshopper ketone; (?)-Grasshopper ketone; CHEMBL456946; CHEMBL2392400; (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-9-apo-beta-caroten-9-one; 4-[(2R)-2alpha,4beta-Dihydroxy-2,6,6-trimethylcyclohexylidene]-3-butene-2-one More... Molecular Formula: C 13 H 20 O 3: Molecular Weight: 224.3 g/mol: InChI Key: QMXLZUOHZGYGDY-JBGXHEPSSA-N
Repatha (evolocumab) is a monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9) indicated for the treatment of patients with heterozygous familial hypercholesterolemia (HeFH), homozygous familial hypercholesterolemia (HoFH), or patients with atherosclerotic heart disease who require additional lowering of ...
How Evolocumab Works. Evolocumab is a highly specific antibody that keeps the body's LDL receptors from breaking down. âThis keeps LDL receptors active on the liver cell surface so they can keep taking LDL [cholesterol] out of the blood,â Robinson said.