Grasshopper ketone; (?)-Grasshopper ketone; CHEMBL456946; CHEMBL2392400; (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-9-apo-beta-caroten-9-one; 4-[(2R)-2alpha,4beta-Dihydroxy-2,6,6-trimethylcyclohexylidene]-3-butene-2-one More... Molecular Formula: C 13 H 20 O 3: Molecular Weight: 224.3 g/mol: InChI Key: QMXLZUOHZGYGDY-JBGXHEPSSA-N
Repatha (evolocumab) is a monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9) indicated for the treatment of patients with heterozygous familial hypercholesterolemia (HeFH), homozygous familial hypercholesterolemia (HoFH), or patients with atherosclerotic heart disease who require additional lowering of ...
(evolocumab) for Subcutaneous Injection. Evolocumab is a human monoclonal immunoglobulin G2 (IgG2) directed against human proprotein convertase subtilisin kexin 9 (PCSK9). Evolocumab has an approximate molecular weight (MW) of 144 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. REPATHA is a sterile, preservative-free, clear to opalescent, colorless to pale yellow solution for subcutaneous administration. Each 1 mL single-use prefilled syringe and single-use prefilled SureClickÂ® autoinjector contains 140 mg evolocumab, acetate (1.2 mg), polysorbate 80 (0.1 mg), proline (25 mg) in Water for Injection, USP.