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1 When blood clots occur in a vein, symptoms may include. 2  pain, 3  swelling, 4  warmth, and. 5  redness. 6  If a forms in a vein in a leg or arm breaks; breaks off and travels to the lung a pulmonary embolus can occur. 7  Symptoms of pulmonary embolism are chest pain and shortness of breath.
Seek emergency medical care if you have leg swelling and any of the following signs or symptoms, which may indicate a blood clot in your lungs or a serious heart condition: 1  Chest pain. 2  Difficulty breathing. 3  Shortness of breath with exertion or lying flat in bed.  Fainting or 1  dizziness. Coughing blood.