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Salmeterol is a long-acting beta2-adrenoceptor agonist (LABA), used in moderate to severe persistent asthma following previous treatment with a short-acting beta2-adrenoceptor agonist (SABA) such as salbutamol (albuterol).he primary noticeable difference of salmeterol from salbutamol, and other short-acting beta2-adrenoceptor agonists (SABAs), is its duration of action. Salmeterol lasts approximately 12 hours in comparison with the salbutamol, which last about 4â6 hours.
Long-Acting Asthma Inhalers â Bronchodilator Drugs. These are less common and come in a different colour, as they're usually green inhalers. They also belong to the class of bronchodilators and they are effective for up to 12 hours.Salmeterol is one of the most common long-acting bronchodilators, along with Formoterol.lue Inhalers â Bronchodilator Drugs. This is the most common group of inhalers (also called reliever inhalers) which contain bronchodilator drugs (usually salbutamol). Bronchodilator simply means that the drug allows the airways in your lungs to dilate and let more air in.