Chest pain and shortness of breath if blood clots form in the blood vessels in your lungs and heart. Pain, redness, warmth, and swelling in the lower leg if blood clots form in the deep veins of your leg. Headaches, speech changes, paralysis (an inability to move), dizziness, and trouble speaking and understanding if blood clots form in the blood vessels in your brain. These signs and symptoms may indicate a stroke.
From Wikipedia, the free encyclopedia. A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism 's genes is made inoperative (knocked out of the organism). knockout mouse (left) that is a model of obesity, compared with a normal mouse. A conditional knockout allows gene deletion in a tissue or time specific manner. This is done by introducing short sequences called loxP sites around the gene.
Problem 9. You are making a knockout of the huntingtin gene in mice and decide to use a mutation in the FGF5 gene to track the contribution of ES cells to the germline. Mice homozygous wildtype (FF) or heterozygous for the FGF5 gene (Ff) have normal fur, but mice homozygous for the FGF5 mutation are very furry (ff).n an ES cell homozygous for the Amendment21 gene, you knock out a single allele of Amendment21 and introduce the resulting cells into a host blastocyst that is homozygous for the Ammendment18 allele. The blastocyst is a transgenic that causes all of its cells to express the red fluorescent protein, RFP.