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Salmeterol is a long-acting beta2-adrenoceptor agonist (LABA), used in moderate to severe persistent asthma following previous treatment with a short-acting beta2-adrenoceptor agonist (SABA) such as salbutamol (albuterol).he primary noticeable difference of salmeterol from salbutamol, and other short-acting beta2-adrenoceptor agonists (SABAs), is its duration of action. Salmeterol lasts approximately 12 hours in comparison with the salbutamol, which last about 4â6 hours.
Fluticasone and salmeterol are the active ingredients in Advair (and other medications), but they are not a generic version of Advair. What can be confusing is that, oftentimes, the active ingredient of a drug is referred to as its generic name..urrently, the company holds the exclusive rights to make and market Advair in the United States. Because there are many different patents for Advair listed with the FDA, it is difficult (probably impossible) to accurately predict when a generic version may become available.