Fatigue may be related to: 1  Use of alcohol or drugs. 2  Excess physical activity. 3  Jet lag.  Lack of physical 1  activity. Lack of sleep.  Medications, such as antihistamines, cough 1  medicines. Unhealthy eating habits.
A directive shall be binding, as to the result to be achieved, upon each Member State to which it is addressed, but shall leave to the national authorities the choice of form and methods. A decision shall be binding in its entirety upon those to whom it is addressed.
Regulation is the act of controlling, or a law, rule or order. An example of a regulation is the control over the sale of tobacco. An example of a regulation is a law that prevents alcohol from being sold in certain places.