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DNA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule. Thus, it is a POLAR molecule which allows it to interact in an aqueous environment.NA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule.
The strands of DNA run anti-parallel, or in opposite directions: the 5â end of one strand is paired with the 3â end of the other. This is illustrated in the figure below. This structure places the non-polar bases of DNA in the center of the double-stranded molecule, surrounded by the charged phosphate groups. This has two functional consequences. First, remember that like charges repel each other.