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DNA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule. Thus, it is a POLAR molecule which allows it to interact in an aqueous environment.NA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule.
The DNA duplex has polarity. One end of each DNA strand is called 5' (prime) end because the last deoxyribose unit at this end has carbon at position 5, free.Similarly, the other end of the strand is termed 3' (prime) because the last deoxyribose unit has carbon at position 3, free.Himadrisekhar S Â· 8 years ago.f a phosphate group is attached to the 5â² end, ligation of two nucleotides can occur, via a phosphodiester bond from the 5â²-phosphate to the 3â²-hydroxyl group of another nucleotide. If it is removed no ligation can occur.