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The four most common teratogens are  tobacco, alcohol, medications and illegal drugs. Teratogens are substances that could harm a developing fetus by affecting growth and causing birth defects or death.
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, with over 40,000 new cases per year in the US. Of all primary HNSCCs, oropharyngeal carcinomas are the third most common, with the tonsil being the most common site of malignancy within the oropharynx. Historically, the standard treatment of tonsil cancer has consisted of surgery with or without adjuvant radiotherapy.