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The four most common teratogens are  tobacco, alcohol, medications and illegal drugs. Teratogens are substances that could harm a developing fetus by affecting growth and causing birth defects or death.
Sacrococcygeal teratomas are the most common type of germ cell tumors (both benign and malignant) diagnosed in neonates, infants, and children younger than 4 years. SCTs occur more often in girls than in boys; ratios of 3:1 to 4:1 have been reported.