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Meatloaf is done when a meat thermometer inserted in its center reads 160 degrees Fahrenheit. Ground beef used for food items like hamburgers or meatloaf should be at this temperature after it is cooked.
Directions. 1  Heat oven to 350ÂºF. Melt butter in a small skillet over medium-high heat. 2  Add ground turkey, breadcrumbs, egg, ketchup, Worcestershire sauce, pepper and salt, if desired to turkey mixture; mix well. 3  Bake 1 hour or until the internal temperature of meatloaf is well-done, 165ÂºF as measured by a meat thermometer.