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p53, also known as TP53 or tumor protein (EC :2.7.1.37) is a gene that codes for a protein that regulates the cell cycle and hence functions as a tumor suppression.It is very important for cells in multicellular organisms to suppress cancer.53 has been described as the guardian of the genome, referring to its role in conserving stability by preventing genome mutation (Strachan and Read, 1999). The name is due to its molecular mass: it is in the 53 kilodalton fraction of cell proteins.
Top of page. p53 is a gene which codes for a protein found in the nucleus of every cell in the human body and many other species. The p53 protein's main role is to prevent cancer cells evolving.p53 both stops damaged cells dividing and may encourage such cells to suicide. If your p53 is damaged, it may be repaired.he p53 gene, which is found in the nucleus of every cell in the human body, is known as the guardian of the genome. The genome is the technical name of genetic information: DNA. Every day, DNA in many of our cells copies itself, and every day a few errors are made in this process.