Fatigue may be related to: 1  Use of alcohol or drugs. 2  Excess physical activity. 3  Jet lag.  Lack of physical 1  activity. Lack of sleep.  Medications, such as antihistamines, cough 1  medicines. Unhealthy eating habits.
Difference between a Regulation, Directive and Decision. Regulations have binding legal force throughout every Member State and enter into force on a set date in all the Member States.
A regulation, unlike a decision, applies to more than an identifiable or defined limited number of persons. It is binding in its entirety, unlike a directive, which simply sets out the aim to be achieved.