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Generic Name: glipizide (GLIP i zide) Brand Names: GlipiZIDE XL, Glucotrol, Glucotrol XL. Do not use this medication if you are allergic to glipizide, or if you are in a state of diabetic ketoacidosis. Call your doctor for treatment with insulin.
1 Glipizide is part of a class of diabetes medications called sulfonylureas. A sulfonylurea, such as glipizide, helps the pancreas make more insulin. It also helps the cells respond to insulin better. This helps to lower blood sugar and keep it under better control.  Metformin works in several ways.