Confidence votes 1.2K. An Anglo-Saxon is a member of one of the Germanic peoples, the Angles, the Saxons, and the Jutes, who settled in Britain in the fifth and sixth centuries.OR it could be a person of English or Anglo-Saxon ancestry.Answer.nglo-Saxon is a collective term for all the Germanic peoples groups who came to inhabit the former Roman Province of Britannia after the legions withdrew from 410 A.D. of English decent.
The Endoplasmic Reticulum essentially aids in cellular homeostasis by providing the main transport mechanism for proteins within the cell.
Thus, forced interaction of cell surface proteins with Derlin-1 is sufficient to induce their degradation via ERAD. Taken together, these results suggest that the main role of US11 is to recruit MHC-I molecules to Derlin-1, which then mediates the dislocation of MHC-I molecules into the cytosol for degradation.