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1 When blood clots occur in a vein, symptoms may include. 2  pain, 3  swelling, 4  warmth, and. 5  redness. 6  If a forms in a vein in a leg or arm breaks; breaks off and travels to the lung a pulmonary embolus can occur. 7  Symptoms of pulmonary embolism are chest pain and shortness of breath.
Signs and symptoms of a blood clot in the leg or deep vein thrombosis occur in the affected leg when a clot obstructs blood flow and causes inflammation. Signs and symptoms of DVT may include: Swelling; Gradual onset of pain; Redness; Warmth to the touch; Worsening leg pain when bending the foot; Leg cramps, especially at night, and often starting in the calf