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Salmeterol is a long-acting beta2-adrenoceptor agonist (LABA), used in moderate to severe persistent asthma following previous treatment with a short-acting beta2-adrenoceptor agonist (SABA) such as salbutamol (albuterol).he primary noticeable difference of salmeterol from salbutamol, and other short-acting beta2-adrenoceptor agonists (SABAs), is its duration of action. Salmeterol lasts approximately 12 hours in comparison with the salbutamol, which last about 4â6 hours.
Inhaler, AccuhalerÂ®, and EvohalerÂ®. Salmeterol is called a bronchodilator because it widens (dilates) your airways. It works by opening up the air passages in your lungs so that air can flow into your lungs more freely. This helps to ease symptoms such as coughing, wheezing and feeling breathless.