A fontanel may be soft and depressed as a result of dehydration. Also spelled fontanelle, fonticulus. Fontanels. fontanel Fontanelle, soft spot Anatomy A membrane-covered region on the skull of a fetus/infant, which corresponds to the convergence of suture lines, where ossification has not yet occurred fontanel
(February 2012) (Learn how and when to remove this template message) Tibial dyschondroplasia (TD) is a metabolic disease of young poultry that affects the growth of bone and cartilage. Often occurs in broilers (chickens raised for meat) and other poultry which have been bred for fast growth rates.
Pathophysiology. Achondroplasia is caused by mutations in the fibroblast growth factor receptor-3 (FGFR3) gene. Mutations within FGFR3 are the only genetic changes known to cause achondroplasia. FGFR3 has been mapped to the short arm of chromosome 4, p16.3 (4p16.3).ackground. Achondroplasia, a nonlethal form of chondrodysplasia, is the most common type of short-limb dwarfism. This skeletal dysplasia is inherited as a Mendelian autosomal dominant trait with complete penetrance.