Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
6 Common Causes of Swollen Legs Due to Inflammation Gout: a form of inflammatory arthritis that develops in some people who have high levels of uric acid in the blood. The build up of uric acid could result in sudden, severe attacks of pain, redness and tenderness in joints especially near the base of the big toe.