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DNA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule. Thus, it is a POLAR molecule which allows it to interact in an aqueous environment.NA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule.
Answers. Best Answer: DNA and RNA are both quite soluble in water. The cytosol of the cell is primarily composed of water, so if DNA and RNA weren't water soluble, they wouldn't happily stay put.In both DNA and RNA, the phosphate groups in the sugar-phosphate backbone of the nucleic acid strands have partial negative charges at cellular pH.This means that they attract polar water molecules and can thus be dissolved in solution.he-OH group of the alcohol is able to get in and bind to all the polar and charged portions of the DNA. Once this happens, the rest of the exposed portions of the alcohol molecules are nonpolar, so they don't mix with the water and the DNA bound by alcohol becomes visible.