1 The first bomb dropped on Hiroshima was made from uranium. 2  The bomb dropped on Nagasaki was made from plutonium, which was even more powerful than uranium. 3  It is thought that at least 135,000 people died from the Hiroshima explosion and another 70,000 in Nagasaki.
Pharmacokinetic parameters of paclitaxel following 3- and 24-hour infusions of TAXOL at dose levels of 135 and 175 mg/m2 were determined in a Phase 3 randomized study in ovarian cancer patients and are summarized in the following table.
An infusion rate of 17mL/min allows an entire unit of blood to be transfused in 30 minutes. The usual recommended time period ranges between 1.5 and 2 hours per unit. The maximum time period allowed for infusion of a single unit of blood is 4 hours. In emergency situations, the infusion rate is not as well established.