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No one really knows what causes asthma. What we do know is that asthma is a chronic inflammatory disease of the airways. The causes of asthma symptoms can vary from person to person. Still, one thing is consistent with asthma: when airways come into contact with an asthma trigger, the airways become inflamed, narrow, and fill with mucus.
Asthma causes the airways of the lungs to swell and narrow, leading to wheezing, shortness of breath, chest tightness, and coughing. It is distinguished by bronchial hyper-responsiveness, which is an exaggerated response of the airway characterized by swelling (edema) and infiltration of inflammatory immune cells.