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The next layer after the mucosa is called the submucosa. This layer is a thick layer of loose connective tissue. Although this layer does not have any sub-layers, it does have blood vessels, vessels belonging to the lymphatic system, and nerves, some of which control digestion.In some places, such as the small intestine, the submucosa also contains cells that secrete mucus onto the surface of the tract.After the submucosa is a layer called the muscularis externa. Except for the upper portion of the esophagus, this layer consists of smooth muscle.n some places, such as the small intestine, the submucosa also contains cells that secrete mucus onto the surface of the tract. After the submucosa is a layer called the muscularis externa. Except for the upper portion of the esophagus, this layer consists of smooth muscle.
Most of the tissue in the digestive tract itself has four layers. These layers are called the mucosa, the submucosa, muscularis externa, and the serosa. The layer in the innermost part of the digestive tract is called the mucosa.his mucus lubricates the digestive tract. The lamina propia is a sub-layer that is made of loose connective tissue. The muscularis mucosae is a sub-layer of smooth muscle. The next layer after the mucosa is called the submucosa. This layer is a thick layer of loose connective tissue.