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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
A rash can also develop after use of some HIV medications. The three main classes of anti-HIV drugs used in the disease's treatment can also cause skin rashes. NNRTIs such as nevirapine (Viramune) are the most common cause of medication skin rashes. Whether caused by an HIV medication or by the disease itself, an HIV rash typically occurs on the chest, back, arms, legs, and face (although it can show up on any part of your body). The rash is usually not found on the mucous membranes (mouth, nostrils, eyes, genitals), palms of the hands, or in between the fingers.