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A high number of large platelets (high MPV) in a person with a low platelet count suggests the bone marrow is producing platelets and releasing them into circulation rapidly. Conversely, the MPV may be low in people with low platelet counts due to a disorder affecting production by the bone marrow.
Having a Low MPV indicates that the platelet count in your blood is lower than normal and that you are in danger of suffering more blood loss in case you get injured. Besides this, a low MPV is also considered a symptom of many other diseases and disorders.t is a reading which represents the size of the platelets in a blood sample and is determined by a machine. CBC or Complete Blood Profile is the test in which the calculation of this reading is usually included.