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The next layer after the mucosa is called the submucosa. This layer is a thick layer of loose connective tissue. Although this layer does not have any sub-layers, it does have blood vessels, vessels belonging to the lymphatic system, and nerves, some of which control digestion.In some places, such as the small intestine, the submucosa also contains cells that secrete mucus onto the surface of the tract.After the submucosa is a layer called the muscularis externa. Except for the upper portion of the esophagus, this layer consists of smooth muscle.n some places, such as the small intestine, the submucosa also contains cells that secrete mucus onto the surface of the tract. After the submucosa is a layer called the muscularis externa. Except for the upper portion of the esophagus, this layer consists of smooth muscle.
Surrounding the mucosa is the submucosa layer of the stomach. The submucosa is made up of various connective tissues, blood vessels, and nerves. Connective tissues support the tissues of the mucosa and connect it to the muscularis layer. The blood supply of the submucosa provides nutrients to the wall of the stomach. Nervous tissue in the submucosa monitors the contents of the stomach and controls smooth muscle contraction and secretion of digestive substances. Muscularis. The muscularis layer of the stomach surrounds the submucosa and makes up a large amount of the stomachâs mass. The muscularis is made of 3 layers of smooth muscle tissue arranged with its fibers running in 3 different directions. These layers of smooth muscle allow the stomach to contract to mix and propel food through the digestive tract. Serosa