Both Panadeine and Sudafed contain paracetamol, so if you took a full dose of each together you would be exceeding the recommended paracetamol dose. I suppose if you really wa â¦ nted the effects of both pills you could take a half dose (one tablet) of each.3 people found this useful.t won't harm you as long as you keep to the dosages recommended for each. For chronic users, however, this combo made lead to some insomnia. Warning: I was takin â¦ g 10mg oxycodone every 3-4 hours when I took one Sudafed.
What causes scleroderma is still a mystery; sufferers of scleroderma will experience a buildup of collagen in the skin and other organs and this is what leads to the symptoms of the disease.
Besides thickening and hardening of the skin, scleroderma can cause skin to lose elasticity and become shiny as it stretches across bones. Other symptoms include: 1  Numbness, pain or color changes in fingers, toes, cheeks, nose and ears, often brought on by cold or emotional distress.rint. Scleroderma means hard skin, although it affects the joints, blood vessels and organs. Also known as systemic sclerosis, scleroderma always affects the skin, causing hard, oval-shaped patches or streaks of thickened skin on the arms, legs and forehead.