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In addition, the neurotransmitter can bind to any one of the nearby smooth muscle cells, a flexibility not found in the NMJ. The chemicals that influence smooth muscle cells: As you'll recall, there is only one neurotransmitter released at the neuromuscular junction-acetylcholine.
Unlike skeletal muscle, there is no specialized connection between the nerve fiber and the smooth muscle cell. The nerve fibers essentially passes close to the smooth muscle cells and releases the neurotransmitter (which is not restricted to acetylcholine-see below) from swellings in the fiber, called varicosities.n addition, the neurotransmitter can bind to any one of the nearby smooth muscle cells, a flexibility not found in the NMJ. The chemicals that influence smooth muscle cells: As you'll recall, there is only one neurotransmitter released at the neuromuscular junction-acetylcholine.