Both Panadeine and Sudafed contain paracetamol, so if you took a full dose of each together you would be exceeding the recommended paracetamol dose. I suppose if you really wa â¦ nted the effects of both pills you could take a half dose (one tablet) of each.3 people found this useful.t won't harm you as long as you keep to the dosages recommended for each. For chronic users, however, this combo made lead to some insomnia. Warning: I was takin â¦ g 10mg oxycodone every 3-4 hours when I took one Sudafed.
What causes scleroderma is still a mystery; sufferers of scleroderma will experience a buildup of collagen in the skin and other organs and this is what leads to the symptoms of the disease.
The signs and symptoms of systemic scleroderma usually begin with episodes of Raynaud phenomenon, which can occur weeks to years before fibrosis.In Raynaud phenomenon, the fingers and toes of affected individuals turn white or blue in response to cold temperature or other stresses.n addition, people with systemic scleroderma often have open sores (ulcers) on their fingers, painful bumps under the skin (calcinosis), or small clusters of enlarged blood vessels just under the skin (telangiectasia).