As part of its ongoing process to make AP course and exam materials more effective for teachers and their students, the College Board released to educators a redesigned AP U.S. Government and Politics Curriculum Framework (.pdf/3.1MB). The redesigned course and exam will launch in the 2018-19 school year.
Ideally, best times of day to supplement with creatine would be around 30 minutes to 1 hour before your training session and immediately post-workout alongside your protein shake.
The first are the changes in intracellular water retention. Creatine requires additional water in order to restore in your muscle tissue. After your muscle become completely saturated with creatine and this usually happens about 3 weeks after supplementing with 5 grams daily.