Profound sedation, respiratory depression, coma, and death may result from the concomitant use of Buprenex with benzodiazepines or other CNS depressants (e.g., non-benzodiazepine sedatives/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, other opioids, alcohol).
The MOU is developed through a process of negotiation and mutual assent, finalized through acceptance of the MOU instrument, and approved by the appropriate agency representatives who signify such approval by signing the MOU.
A mol is an expression of the molair weight of a molecule, derived from the weight of a hydrogen molecule, which is 1 mol. Hydrogen has a relative atomic mass of 1 g/ mol and oxygen has a relative atomic mass of 16 g/ mol. Water consists of one oxygen atom and two hydrogen atoms. This means that the mass of a water molecule is 1g + 1g + 16g = 18 g/ mol.