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No one really knows what causes asthma. What we do know is that asthma is a chronic inflammatory disease of the airways. The causes of asthma symptoms can vary from person to person. Still, one thing is consistent with asthma: when airways come into contact with an asthma trigger, the airways become inflamed, narrow, and fill with mucus.
Both. and COPD, or. obstructive pulmonary disease, involve blocked airways. The difference between the two is that the blocked airways of asthma typically open up completely with medication, while the airways with COPD may be partially opened with medication.ther differences between the two include: 1  Asthma attacks come and go. 2  The COPD cough usually (but not always) results in mucus production and may or may not involve wheezing. 3  COPD flare-ups, called exacerbations, are a severe worsening of symptoms. 4  or viruses or other exposures.