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Amlodipine is a drug that is used for angina, arrhythmias, chest  pain, and hypertension. It can stay in your system for between 7  and 10 days.   Yes, there's no problem in taking those 2 drugs together. However, Nyquil might contains phenylephrine or pseudoephedrin and this drug might increase blood pressure (froâ¦m 5-10 mmhg).
Amlodipine is widely distributed, with a volume of distribution of 16 to 21 L/kg, and is highly protein bound (approximately 93%). It is extensively metabolized by the liver to inactive metabolites.Elimination is bi-phasic, with a terminal half-life of 30 to 50 hours in adults.mlodipine is widely distributed, with a volume of distribution of 16 to 21 L/kg, and is highly protein bound (approximately 93%). It is extensively metabolized by the liver to inactive metabolites.