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If you have severe pulmonary hypertension, your doctor may prescribe medications called calcium channel blockers. These medicines lower blood pressure in the lungs and the rest of the body. If calcium channel blockers arenât enough, your doctor may refer you to a specialized treatment center.
The World Health Organization classifies human. pulmonary hypertension into five groups based on the. inciting cause (see box on page 7). Pulmonary hypertension causes pressure overload. on the right heart and can result in right ventricular. enlargement (concentric hypertrophy or thickening). This is called cor pulmonale. Acute cor pulmonale, most often caused by massive thromboembolic dis-. ease, results in right ventricular dilation, tricuspid.