On average, the life expectancy of peritoneal mesothelioma patients is 12 months. However, multiple studies have shown that patients who have cytoreduction with HIPEC experience significantly longer survival times. Many patients now survive up to 5 years and some even live beyond 7 years.
It was written by co-creator Mark Gatiss, who also portrays Mycroft Holmes, Sherlock's brother in the series, and was directed by Paul McGuigan. The episode is a contemporary adaptation of The Hound of the Baskervilles, one of Sir Arthur Conan Doyle 's most famous works.
1 In the Billy Wilder-directed film The Private Life of Sherlock Holmes (1970), which starred Robert Stephens as Sherlock, Mycroft was played by Christopher Lee (who also played Sherlock Holmes in other productions before and since).