The combination drug, formerly known as LCZ696, is the first approved agent in the angiotensin receptor-neprilysin inhibitor (ARNI) class and exerts its effect within and beyond the renin-angiotensin system.
Hatred (or hate) is a deep and emotional extreme dislike. It can be directed against individuals, groups, entities, objects, behaviors, or ideas. Hatred is often associated with feelings of anger, disgust and a disposition towards hostility.
something that is a source of irritation the constant need to cut costs was a hair shirt, but one that the theater company had to live with Synonyms aggravation, aggro [British], bother, botheration, bugbear, exasperation, frustration, annoyance, hassle, headache, inconvenience, irk, irritant, nuisance, peeve, pest, rub, ruffle, thorn, trial, ...