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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Rash on arms and legs of children can be seen due to various factors like: 1  Chicken pox caused by a virus leading to very itchy blisters. 2  Measles, which is a respiratory infection.  3 Scarlet fever caused by streptococcal infection and requires antibiotics.  Hand, foot and mouth disease, which causes red lesions.