Both Panadeine and Sudafed contain paracetamol, so if you took a full dose of each together you would be exceeding the recommended paracetamol dose. I suppose if you really wa â¦ nted the effects of both pills you could take a half dose (one tablet) of each.3 people found this useful.t won't harm you as long as you keep to the dosages recommended for each. For chronic users, however, this combo made lead to some insomnia. Warning: I was takin â¦ g 10mg oxycodone every 3-4 hours when I took one Sudafed.
What causes scleroderma is still a mystery; sufferers of scleroderma will experience a buildup of collagen in the skin and other organs and this is what leads to the symptoms of the disease.
Signs and Symptoms. Scleroderma can affect everyone differently. The following are some of the general symptoms associated with the condition. Skin changes, including: 1  Hardening of your skin, particularly on your hands, arms and face, and occasionally on your trunk and legs. 2  Loss of hair over the affected area.3  Change in skin color.cleroderma can affect everyone differently. The following are some of the general symptoms associated with the condition. Skin changes, including: 1  Hardening of your skin, particularly on your hands, arms and face, and occasionally on your trunk and legs. 2  Loss of hair over the affected area. 3  Change in skin color.