With venom capable of killing a full gown elephant, the King Cobra is the most poisonous snake known to the world. The King cobraâs venom also contains a unique protein called ohanin. Ohanin is being used today in the form of a painkiller that is 20 times more potent than morphine.
Eluxadoline is a Î¼- and Îº-opioid receptor agonist and Î´-opioid receptor antagonist that acts locally in the enteric nervous system, possibly decreasing adverse effects on the central nervous system.ollowing a 100 mg dose of eluxadoline, the Cmax was about 2 to 4 ng/ml and AUC was 12-22 ng.h/ml. Eluxadoline has linear pharmacokinetics with no accumulation upon repeated twice daily dosing. Its plasma protein binding was 81% and its half life was 3.7 to 6 hours and it was excreted mainly in feces.
Amitriptyline is the generic name for the drug amitriptyline hydrochloride. First developed as Elavil by the American pharmaceutical giant Merck & Co., Inc., this prescription medication is used to treat depression, eating disorders, post-herpetic neuralgia, and migraine headaches.mitriptyline belongs to the tricyclic antidepressant (TCA) drug class, which behaves similar to more recently developed serotonin-norepinephrine reuptake inhibitors (SNRIs). Both classes prevent receptors in the human brain from absorbing serotonin that has already been released.