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No one really knows what causes asthma. What we do know is that asthma is a chronic inflammatory disease of the airways. The causes of asthma symptoms can vary from person to person. Still, one thing is consistent with asthma: when airways come into contact with an asthma trigger, the airways become inflamed, narrow, and fill with mucus.
This narrows the space for air to move in and out of the lungs. The muscles that wrap around your airways also can tighten, making breathing even harder. When that happens, it's called an asthma flare-up, asthma episode or asthma attack.. After an asthma flare-up, you probably will feel tired.