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Amlodipine is a drug that is used for angina, arrhythmias, chest  pain, and hypertension. It can stay in your system for between 7  and 10 days.   Yes, there's no problem in taking those 2 drugs together. However, Nyquil might contains phenylephrine or pseudoephedrin and this drug might increase blood pressure (froâ¦m 5-10 mmhg).
The terminal plasma elimination half- life is about 35-50 hours and is consistent with once daily dosing. Amlodipine is extensively metabolised by the liver to inactive metabolites with 10% of the parent compound and 60% of metabolites excreted in the urine.