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The mucosa-associated lymphoid tissue (MALT) (also called mucosa-associated lymphatic tissue) is a diffuse system of small concentrations of lymphoid tissue found in various sites of the body, such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin. D-MALT (diffuse mucosa-associated lymphatic tissue); MALT that is not organized as a separately macroscopically anatomically identifiable mass, tissue or organ (such as the aforementioned O-MALT) is diffuse MALT.
Mucosal-associated Lymphoid Tissue (MALT) refers to the unencapsulated lymphoid tissue distributed in association with mucosal tissues, primarily within their lamina propria. Histology The key feature of MALT is its presence in the mucosal lamina propria and its unencapsulated nature. MALT can appear as aggregations of immune cells roughly similar in architecture to a section of a lymph node and may contain lymphoid follicles with germinal centers. Unlike lymph nodes, MALT aggregations are not penetrated by lymphatic vessels and are exposed to antigens directly from the mucosa they surround. In addition, MALT refers to the diffusely distributed immune cells, usually lymphocytes, found throughout the lamina propria of mucosa. Function Given the enormous microbial burden present at mucosal surfaces, MALT provides the immune system easy histological access to the organisms.