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A high number of large platelets (high MPV) in a person with a low platelet count suggests the bone marrow is producing platelets and releasing them into circulation rapidly. Conversely, the MPV may be low in people with low platelet counts due to a disorder affecting production by the bone marrow.
A platelet count is used to detect the number of platelets in the blood. The test is included in a complete blood count (CBC) , a panel of tests often performed as part of a general health examination.Platelets are tiny fragments of cells that are essential for normal blood clotting.xamples of conditions causing a low platelet count include: 1  Idiopathic thrombocytopenia (ITP), also known as immune thrombocytopenic purpura, is the result of antibody production against platelets.