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Certain heart diseases. Heart diseases, including aortic valve disease, left heart failure, mitral valve disease, and congenital heart disease, can also cause pulmonary hypertension. Thromboembolic disease. A blood clot in a large pulmonary artery can result in the development of pulmonary hypertension.
There are many different treatments for pulmonary vascular disease. Pulmonary vascular disease is treated according to its cause. Pulmonary embolism: Blood clots to the lungs are treated with blood thinners (anticoagulation). The most often used medicines are heparin, enoxaparin (Lovenox) and warfarin (Coumadin).