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A high number of large platelets (high MPV) in a person with a low platelet count suggests the bone marrow is producing platelets and releasing them into circulation rapidly. Conversely, the MPV may be low in people with low platelet counts due to a disorder affecting production by the bone marrow.
Top 10 Causes Of Low Platelets In Adults And Babies 1. Immune â Mediated Thrombocytopenic Purpura. One of the major of low platelets is the immune â mediated thrombocytopenic purpura sometimes known as ITP. This is a condition which is marked by the antibodies development against platelets. The attack of antibodies to the normal cells can be what causes the low platelets count levels in the patients who suffer from ITP. Then, it will lead to immune â mediated thrombocytopenia. Furthermore, there are two forms of ITP: chronic and acute.