Acromegaly (hypersomatotropism) is an endocrine disorder characterized by progestin-induced hypersecretion of growth hormone (GH) by mammary hyperplasia, with resultant overgrowth of the soft tissue, bone, and viscera. In humans and cats, acromegaly is commonly caused by pituitary adenomas producing GH. Rare cases of pituitary adenomas resulting in acromegaly have been reported in dogs, but acromegaly is usually caused by GH production at hyperplastic mammary glands or mammary adenocarcinoma.
These pro-early neuter studies were not carried out long enough to evaluate the risk of cancer. In my experience, dogs neutered under 6 months develop less obesity and donât establish some of the âmaleâ behaviors that neutering is meant to treat. They are also less likely to jump a fence, fight, or get hit by a car.
1 Once male pups are eight weeks old, it's likely that their testicles have fully descended, which is a necessary condition for performing the surgery. 2  According to the ASPCA, spaying and neutering can occur as early as eight weeks.eutering dogs at an early age can actually keep some dogs from developing negative behavior patterns. Issues may include: 1  Aggressive behavior in some male dogs once they become sexually mature.