The combination drug, formerly known as LCZ696, is the first approved agent in the angiotensin receptor-neprilysin inhibitor (ARNI) class and exerts its effect within and beyond the renin-angiotensin system.
Hatred (or hate) is a deep and emotional extreme dislike. It can be directed against individuals, groups, entities, objects, behaviors, or ideas. Hatred is often associated with feelings of anger, disgust and a disposition towards hostility.
Another relative, albeit a distant one, is the English word spurn, meaning to reject. Lest you wish to exasperate your readers, you should take care not to confuse exasperate with the similar-sounding exacerbate, another Latin-derived verb that means to make worse, as in Their refusal to ask for help only exacerbated the problem.