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Although it is no bigger than a pea, the pituitary gland, located at the base of the brain just beneath the hypothalamus, is considered the most important part of the endocrine system. It's often called the master gland because it makes hormones that control several other endocrine glands.
The major glands of the endocrine system are the hypothalamus, pituitary, thyroid, parathyroids, adrenals, pineal body the reproductive organs and the pancreus. The Hypothalamus. The hypothalamus is located in the lower central part of the brain. This part of the brain is important in regulations of satiety, metabolism and body temp.