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No one really knows what causes asthma. What we do know is that asthma is a chronic inflammatory disease of the airways. The causes of asthma symptoms can vary from person to person. Still, one thing is consistent with asthma: when airways come into contact with an asthma trigger, the airways become inflamed, narrow, and fill with mucus.
During an asthma attack, breathing is restricted by three physical changes that occur in the lungs, usually as a reaction to an allergen (a substance that can cause an allergic reaction). The most critical factor is the inflammation (swelling) of the lining of the air passages in the lungs.