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If you have severe pulmonary hypertension, your doctor may prescribe medications called calcium channel blockers. These medicines lower blood pressure in the lungs and the rest of the body. If calcium channel blockers arenât enough, your doctor may refer you to a specialized treatment center.
Polycythemia is also associated with hypertension due to increased blood viscosity and thrombosis. Severe, chronic polycythemia secondary to increased blood viscosity can raise pulmonary arterial pressure and cause increased pulmonary resistance with potential hypoxia, resulting in cor pulmonale. Thus, increased hemoglobin and hematocrit secondary to testosterone replacement can be significant and in a recent meta-analysis has been cited as the most common side effect of androgen therapy