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Although it is no bigger than a pea, the pituitary gland, located at the base of the brain just beneath the hypothalamus, is considered the most important part of the endocrine system. It's often called the master gland because it makes hormones that control several other endocrine glands.
Part of the Brain: The Control and Relay Centre of the Endocrine System. (2) Pituitary. Known as the Master Gland, this part of the brain consists of three lobes called anterior, interior and posterior.