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In addition, the neurotransmitter can bind to any one of the nearby smooth muscle cells, a flexibility not found in the NMJ. The chemicals that influence smooth muscle cells: As you'll recall, there is only one neurotransmitter released at the neuromuscular junction-acetylcholine.
The interaction between actin and myosin filaments in the A-band of the sarcomere is responsible for the muscle contraction (sliding filament model).uring stimulation of the muscle cell, the motor neuron releases the neurotransmitter acetylcholine which travels across the neuromuscular junction (the synapse between the terminal bouton of the neuron and the muscle cell). Acetylcholine binds to a post-synaptic nicotinic acetylcholine receptor.