Differentiation is an operation that allows us to find a function that outputs the rate of change of one variable with respect to another variable. Informally, we may suppose that we're tracking the position of a car on a two-lane road with no passing lanes.
Overactive bladder is typically treated with a class of drugs called anticholinergics. Examples include DetrolÂ®, DitropanÂ®, VesicareÂ®, and EnablexÂ®. Mirabegron is a new drug approved for overactive bladder that has a different mechanism of action than the anticholinergics. MECHANISM: Mirabegron (MyrbetriqÂ®) stimulates Beta-3 adrenergic receptors. Stimulation of Beta-3 adrenergic receptors in the bladder muscle causes it to relax.
As previously mentioned, first-generation antihistamines are more easily identified as anticholinergic offenders, but other agents with anticholinergic properties such as digoxin, warfarin, prednisone, and codeine are unlikely to set off alarms among prescribers, or perhaps even among pharmacists.ne unique and rather unanticipated aspect of the study is the link between mortality and anticholinergic burden. As with cognitive impairment, the association between the use of anticholinergic medication and death at 2 years was an observed dose-response effect involving the ACB score.