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Although it is no bigger than a pea, the pituitary gland, located at the base of the brain just beneath the hypothalamus, is considered the most important part of the endocrine system. It's often called the master gland because it makes hormones that control several other endocrine glands.
The hypothalamus is an important part of your neuroendocrine system. It controls the interaction between your endocrine or hormone producing system and certain parts of your nervous system. Your hypothalamus is responsible for producing the hormone that triggers the start of your menstrual cycle.