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Certain heart diseases. Heart diseases, including aortic valve disease, left heart failure, mitral valve disease, and congenital heart disease, can also cause pulmonary hypertension. Thromboembolic disease. A blood clot in a large pulmonary artery can result in the development of pulmonary hypertension.
Pulmonary Hypertension Treatment. In general, the treatment of pulmonary hypertension focuses on treating the underlying cause and managing the symptoms. Early recognition of the disease and appropriate management of the underlying condition is important in order to slow the rate of progression to an advanced stage. Despite advanced treatment options, there is no a cure for pulmonary hypertension.