Genetic variation comes from several sources. Genetic variation comes from two main sources: mutation and recombination. â¢ Mutation A mutation is a random change in the DNA of a gene. This change can form a new allele. Mutations in reproductive cells can be passed on to offspring. This increases the genetic variation in the gene pool.
The medial collateral ligament (MCL) is a broad, thick band that runs down the inner part of the knee, from the femur (thighbone) to about four to six inches from the top of the tibia (shinbone).The MCL's primary function is to prevent the leg from over-extending inward, but it also is part of the mechanism that stabilizes the knee and allows it to ...
LCL Reconstruction. In patients who have a complete lateral, or fibular collateral ligament (LCL), tear and noticeable side-to-side instability with activities, a lateral collateral ligament surgery is recommended. The term fibular collateral ligament (FCL) is more anatomically correct, but is more commonly referred to as lateral collateral ligament (LCL). LCL surgery is very effective in restoring side-to-side stability to the knee and preventing varus gapping.