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Total iron binding capacity (TIBC) is a blood test to see if you have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.
A total iron-binding capacity (TIBC or transferrin) test is used to measure the amount of iron in the body. Transferrin is a glyco-protein that's found in blood plasma (the liquid part of blood). It's capable of binding iron and acts as a carrier for iron in the bloodstream. If you have an iron deficiency (a lack of iron in your blood), your iron level will be low but your TIBC will be high.