Profound sedation, respiratory depression, coma, and death may result from the concomitant use of Buprenex with benzodiazepines or other CNS depressants (e.g., non-benzodiazepine sedatives/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, other opioids, alcohol).
The MOU is developed through a process of negotiation and mutual assent, finalized through acceptance of the MOU instrument, and approved by the appropriate agency representatives who signify such approval by signing the MOU.
MOA stands for Minute Of Angle. A full circle is divided into 360 degrees and each degree is divided into 60 minutes. Thus, there are 21,600 minutes in a full circle (360 x 60 = 21,600). A minute is a small angle, but it's exactly what's needed for gun sights. A rule of thumb is that changing a sight's elevation setting by 1 minute of angle changes the bullet's impact point by 1 inch at 100 yards.