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A high number of large platelets (high MPV) in a person with a low platelet count suggests the bone marrow is producing platelets and releasing them into circulation rapidly. Conversely, the MPV may be low in people with low platelet counts due to a disorder affecting production by the bone marrow.
I have answered this question in a previous question. Low platelets have numerous causes and having low platelets may be a manifestation of a deeper medical problem ( autoimmune problems, haematologic malignancies, Lymphomas, anemia, deficiencies). So you can there are a very large number of causes for low platelets. This is just to give you a general idea and a framework to have a better and more elaborate discussion with your doctor. You will need to be examined by your doctor.