Trailhead North provides dedicated desks, conference rooms and integrated space for entrepreneurs. Located in the 8th Street Marketplace in the heart of BoDo and Boise's tech corridor.
1. In some cases, the cofactor completes the active site of the enzyme or modifies it in such a manner that substrate binding can ensue. 2. The cofactor acts as a donor of electrons or atoms to the substrate and following the reaction is returned to its former state.
Figure 1-1: A flow chart of the two types of cofactors. Apoenzyme-An enzyme that requires a cofactor but does not have one bound. An apoenzyme is an inactive enzyme, activation of the enzyme occurs upon binding of an organic or inorganic cofactor. Holoenzyme-An apoenzyme together with its cofactor. A holoenzyme is complete and catalytically active. Most cofactors are not covalently bound but instead are tightly bound. However, organic prosthetic groups such as an iron ion or a vitamin can be covalently bound.