Differentiation is an operation that allows us to find a function that outputs the rate of change of one variable with respect to another variable. Informally, we may suppose that we're tracking the position of a car on a two-lane road with no passing lanes.
Overactive bladder is typically treated with a class of drugs called anticholinergics. Examples include DetrolÂ®, DitropanÂ®, VesicareÂ®, and EnablexÂ®. Mirabegron is a new drug approved for overactive bladder that has a different mechanism of action than the anticholinergics. MECHANISM: Mirabegron (MyrbetriqÂ®) stimulates Beta-3 adrenergic receptors. Stimulation of Beta-3 adrenergic receptors in the bladder muscle causes it to relax.
For example, some studies failed to take into account that some anticholinergic drugs are used to treat depression and insomnia, which can be early warning signs of dementia. If you don't account for that, it looks like the medication is causing the dementia, while it's really those symptoms that are causing that anticholinergic use, Gray said. In the new study, Gray and her colleagues looked at data from the prospective Adult Changes in Thought study, which includes patients from Group Health, a health-care delivery system in Seattle.