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The next layer after the mucosa is called the submucosa. This layer is a thick layer of loose connective tissue. Although this layer does not have any sub-layers, it does have blood vessels, vessels belonging to the lymphatic system, and nerves, some of which control digestion.In some places, such as the small intestine, the submucosa also contains cells that secrete mucus onto the surface of the tract.After the submucosa is a layer called the muscularis externa. Except for the upper portion of the esophagus, this layer consists of smooth muscle.n some places, such as the small intestine, the submucosa also contains cells that secrete mucus onto the surface of the tract. After the submucosa is a layer called the muscularis externa. Except for the upper portion of the esophagus, this layer consists of smooth muscle.
The mucosa, or mucous membrane layer, is the innermost tunic of the wall. It lines the lumen of the digestive tract. The mucosa consists of epithelium, an underlying loose connective tissue layer called lamina propria, and a thin layer of smooth muscle called the muscularis mucosa.In certain regions, the mucosa develops folds that increase the surface area. Certain cells in the mucosa secrete mucus, digestive enzymes, and hormones.Ducts from other glands pass through the mucosa to the lumen. In the mouth and anus, where thickness for protection against abrasion is needed, the epithelium is stratified squamous tissue.ertain cells in the mucosa secrete mucus, digestive enzymes, and hormones. Ducts from other glands pass through the mucosa to the lumen. In the mouth and anus, where thickness for protection against abrasion is needed, the epithelium is stratified squamous tissue.