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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Digestive disorders, thyroid problems, drug reactions and certain cancers are the four main causes of rashes that spread all over the body. Digestive Disorders. There are a number of digestive system disorders that can lead to a full body rash. These include liver disease, kidney problems and Celiac disease. Both the liver and kidneys are responsible for cleaning toxic substances out of the bloodstream. If either of thes. e organs is having problems, those substances can build up and cause a rash to break out all over the body. Severe kidney problems can arise after experiencing direct damage to the kidneys, from having a condition that impairs blood flow or from blockages within the kidneysâ drainage tubes or ureters, that can prevent waste from leaving the body.