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How alcohol and ecstasy affect ADH. Alcohol suppresses ADH production. This causes the kidneys to produce more dilute urine. It can lead to dehydration. Ecstasy increases ADH production. This causes the kidneys to reabsorb water. It can result in the body having too much water.
When youâre thirsty or slightly dehydrated, ADH levels rise. Your kidneys reabsorb more water and put out concentrated urine. If youâve had plenty to drink, ADH levels fall and what comes out is clear and dilute. When your body doesnât make enough ADH, the condition is called central diabetes insipidus. If you make enough but your kidneys can't respond to it, you have nephrogenic diabetes insipidus. In either form, the result is the same. Your kidneys can't retain water, so even if youâre dehydrated, they'll put out a lot of pale, or diluted urine.