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What Is Hyzaar? HyzaarÂ® (losartan potassium-hydrochlorothiazide) is a prescription medicine that has been licensed to treat high blood pressure (hypertension) in adults. However, it is not a cure for high blood pressure. Hyzaar has not been approved for use in children.
The water pill/Cozaar combo is called Hyzaar. It is essentially the same as Hyzaar which contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Losartan is also in a group of drugs called angiotensin II receptor antagonists.