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The mean terminal plasma elimination half-lives of racemic tramadol and racemic M1 are 6.3Â±1.4 and 7.4Â±1.4 hours, respectively. The plasma elimination half-life of racemic tramadol increased from approximately six hours to seven hours upon multiple dosing.
1. Ultra short acting benzos â The half-life of ultra short acting benzodiazepines is less than 5 hours. These drugs are essentially non-accumulating. 2. Short acting and intermediate benzos â This class of benzodiazepines have half-life values from 5-24 hours and can be dosed more frequently.. Ultra short acting benzos â The half-life of ultra short acting benzodiazepines is less than 5 hours. These drugs are essentially non-accumulating. 2. Short acting and intermediate benzos â This class of benzodiazepines have half-life values from 5-24 hours and can be dosed more frequently.