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1 A typical level of HDL-C is between 40-50 mg/dL (1.0-1.3 mmol/L) for men and between 50-59 mg/dl (1.3-1.5 mmol/L) for women and is associated with average risk of heart disease. 2  Based on many epidemiologic studies, HDL-C of 60 mg/dL (1.55 mmol/L) or higher is associated with a less than average risk of heart disease.
In the average man, HDL-cholesterol levels are usually in the range of 1.1-1.4 mmol/L; in women from 1.3-1.6 mmol/L. HDL-cholesterol levels less than 1.0 mmol/L are considered abnormally low. Increasing HDL-cholesterol levels can significantly reduce the risk of heart disease.