Approximately 1 out of every 33 babies in the United States is born with a birth defect. Birth defects can be minor or severe. They may affect appearance, organ function, and physical and mental development. Most birth defects are present within the first three months of pregnancy, when the organs are still forming. Some birth defects are harmless. Others require long-term medical treatment. Severe birth defects are the leading cause of infant death in the United States, accounting for 20 percent of deaths.
NSAIDs comprise a large class of drugs with many different options. In addition to aspirin, there are currently several types of both non-prescription (over-the-counter) NSAIDs and prescription brands of NSAIDs. The three types of NSAIDs most commonly used to treat many types of back pain and neck pain include: 1  Ibuprofen (e.g. brand names Advil, Motrin, Nuprin). 2  Naproxen (e.g. brand names Aleve, Naprosyn). 3  COX-2 inhibitors (e.g. brand name Celebrex).
Nonsteroidal anti-inflammatory drugs (NSAIDs) are most commonly used for relief of mild to moderately severe pain. Although the pain-relieving effects tend to be patient-specific, ibuprofen is usually used for initial therapy. All NSAIDs now have the black box warning for increased cardiovascular risk, even with short-term use, with naproxen having the least risk. Topical diclofenac has been used and may be the only topical NSAID manufactured in the United States,although a compounding pharmacy can compound any NSAID into a topical form.