ESIM - Evaporative System Integrity Monitor, All Acronyms, viewed April 16, 2017, <https://www.allacronyms.com/ESIM/Evaporative_System_Integrity_Monitor>.
Acetylcholine is the neurotransmitter used at the neuromuscular junction âin other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles.
Mechanism of Action. Botulinum toxin acts by binding presynaptically to high-affinity recognition sites on the cholinergic nerve terminals and decreasing the release of acetylcholine, causing a neuromuscular blocking effect. This mechanism laid the foundation for the development of the toxin as a therapeutic tool.