Points to consider prior to initiating RETROVIR in pregnant women for the prevention of maternal-fetal HIV-1 transmission include: â¢ In most cases, RETROVIR for prevention of maternal-fetal HIV-1 transmission should be given in combination with other antiretroviral drugs. â¢ Prevention of HIV-1 transmission in women who have received RETROVIR for a prolonged period before pregnancy has not been evaluated.
Vancomycin is an antibiotic drug used to treat serious, life-threatening infections by gram-positive bacteria that are resistant to less-toxic agents. The reference range for vancomycin trough levels is 10-20 Âµg/mL (15-20 Âµg/mL for complicated infections). The reference range for vancomycin peak levels is 25-50 Âµg/mL. Next. Vancomycin trough concentrations below 10 Âµg/mL are associated with inadequate therapy and an increased risk of developing bacterial resistance. Vancomycin trough concentrations above the therapeutic range may increase the risk of nephrotoxicity.
trough (plural troughs) A long, narrow container, open on top, for feeding or watering animals. One of Hank's chores was to slop the pigs' trough each morning and evening. Any similarly shaped container. (Australia, New Zealand) A rectangular container used for washing or rinsing clothes. Ernest threw his paint brushes into a kind of trough he had fashioned from sheet metal that he kept in the sink.