Therefore, whenever a ddNTP is added to a growing DNA strand, it is unable to chemically bind with the next nucleotide in the chain, and the DNA strand stops growing. Figure 3: By adding together information about all of the truncated strands, researchers can determine the nucleotide sequence of the DNA target.
Functions of the Bladder. Temporary store of urine â The bladder is a hollow organ. The walls are very distensible, with a folded internal lining (known as rugae), this allows it to hold up to 600ml. Assists in the expulsion of urine â During voiding, the musculature of the bladder contracts, and the sphincters relax.
It is composed of connective tissue with elastic fibers. The next layer is the muscularis, which is composed of smooth muscle. The smooth muscle fibers are interwoven in all directions and, collectively, these are called the detrusor muscle. Contraction of this muscle expels urine from the bladder.On the superior surface, the outer layer of the bladder wall is parietal peritoneum. In all other regions, the outer layer is fibrous connective tissue. There is a triangular area, called the trigone, formed by three openings in the floor of the urinary bladder.he inner lining of the urinary bladder is a mucous membrane of transitional epithelium that is continuous with that in the ureters. When the bladder is empty, the mucosa has numerous folds called rugae.