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Levothyroxine is the generic name for the synthetic form of thyroxine, a thyroid hormone replacement drug. This drug contains the synthetic form of one thyroid hormone, T4. Levothyroxine is the most commonly prescribed thyroid hormone replacement drug. Brand names in the U.S: Synthroid, Levothroid, Levoxyl, Unithroid.
Some medicines can affect the way your thyroid drug works, including: 1  Anti-seizure medicines like carbamazepine (Tegretol) and phenytoin sodium (Dilantin) 2  Birth control pills and estrogen. 3  Cancer drugs called tyrosine kinase inhibitors.  Medicines for depression, like sertraline 1  (Zoloft) Testosterone.