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Medical Definition of degenerative. : of, relating to, involving, or tending to cause degeneration degenerative conditions of the nervous systemâMorris Fishbein degenerative changes a degenerative muscle disorder.
What is Degenerative Myelopathy? Canine Degenerative Myelopathy (DM) is a progressive disease of the spinal cord and ultimately the brain stem and cranial nerves which, at itâs end stages, results in complete paralysis and death. The closest human equivalent may be Amyotrophic Lateral Sclerosis, or ALS, also known as Lou Gehrigâs disease.