The long-standing model of pigment cell origins is implicitly based upon a progressive fate restriction model of neural crest development and postulates the existence of a partially restricted progenitor common to all pigment cell types (i.e., a chromatoblast) [38] .
Sodium is the fourth most abundant element on earth, comprising about 2.6% of the earth's crust; it is the most abundant of the alkali group of metals. It is now obtained commercially by the electrolysis of absolutely dry fused sodium chloride.
Sodium, like every reactive element, is never found free in nature. Sodium is a soft, bright, silvery metal which floats on water, decomposing it with the evolution of hydrogen and the formation of the hydroxide. It may or may not ignite spontaneously on water, depending on the amount of oxide and metal exposed to the water.