While ALS is the most common motor neuron disease, we also treat all other forms, including: 1  PLS (Primary Lateral Sclerosis), affecting the upper motor neurons in the brain and spinal cord. 2  PMA (Primary Muscular Atrophy), affecting the lower motor neurons from the spine to the muscle.
Deletion Mutation and DNA. A deletion mutation occurs when part of a DNA molecule is not copied during DNA replication. This uncopied part can be as small as a single nucleotide or as much as an entire chromosome.The loss of this DNA during replication can lead to a genetic disease.eletion Mutation and DNA. A deletion mutation occurs when part of a DNA molecule is not copied during DNA replication. This uncopied part can be as small as a single nucleotide or as much as an entire chromosome.
DNA sequence after insertion of a base. Now the DNA reads a slightly different sequence, and it's longer than before. On the other hand, a deletion would be just the opposite. A deletion is a point mutation in which one or more base pairs is removed from a DNA sequence. If a deletion mutation happened to our strand, then we would lose one base and the DNA strand would end up one base shorter.