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The goal of treatment for advanced Parkinsonâs disease should be on providing patients with safety, comfort, and quality of life. Levadopa (L-dopa) Levodopa, also called L-dopa, which is converted to dopamine in the brain, remains the gold standard for treating Parkinson's disease. The standard preparations (Sinemet, Atamet) combine levodopa with carbidopa, which improves the action of levodopa and reduces some of its side effects, particularly nausea.
Key Facts. 1  The central objective of using Parkinsonâs disease medication is to control or manage motor symptoms. 2  Almost all patients will need levodopa in their management. In general it is recommended that you start with a dopamine agonist if your patient is younger than 50 years; you should consider starting with carbidopa/levodopa if your patient is older than 70 years; either option is good if your patient is between 50 and 70 years old.