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Medical Definition of degenerative. : of, relating to, involving, or tending to cause degeneration degenerative conditions of the nervous systemâMorris Fishbein degenerative changes a degenerative muscle disorder.
(of a human or system) Having lost good or desirable qualities. (of an encoding or function) Having multiple domain elements correspond to one element of the range. The genetic code is degenerate because a single amino acid can be coded by one of several codons. (mathematics) A degenerate case is a limiting case in which a class of object changes its nature so as to belong to another, usually simpler, class. (physics) Having the same quantum energy level.