ANTIDEPRESSANTS. The distinction between depression with psychotic features and psychotic symptoms of dementia may be problematic, especially in patients with a history of depression or prominent negative symptoms.
Repetitive-motion injuries can cause pain in the wrist and hand. Carpal tunnel syndrome is an impingement on the median nerve in the area of the wrist that can cause numbness, tingling, and eventually pain or cramping in the hand. Trauma or injuries such as strains and sprains can also cause wrist pain. De Quervain's disease is an inflammation of the tendons that begins in the thumb and extends to the wrist; this condition is another potential cause of wrist pain. Tumors of the bones or other structures in the hand are a very rare cause of wrist pain. REFERENCE:
De Quervain's may cause pain when you twist your wrist. You might also have pain if you grab something between your thumb and fingers. Many people hear a funny sound like a squeak, crackle, snap, or creak when they move the wrist or thumb. The bottom of the thumb or the side of the wrist might also be sore or swollen. This can make it hard to move your thumb or wrist. The back of the thumb and index finger may also feel numb. Sometimes de Quervain's can cause a small bump on the thumb side of the wrist. If you don't get treatment, the pain can spread up your forearm or down into your thumb.