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Medroxyprogesterone subcutaneous injection (depo-subQ Provera 104Â®) is a prescription medication approved to prevent pregnancy and to manage pain caused by endometriosis. This product contains medroxyprogesterone, a progestin hormone. It is given as a subcutaneous (below the skin) injection every three months.
The injection of a drug or the implantation of a device beneath the surface of the skin is made in the loose interstitial tissues of the upper arm, the anterior surface of the thigh, or the lower portion of the abdomen. The upper back also can be used as a site of subcutaneous administration. The site of injection is usually rotated when injections are frequently given. The maximum amount of medication that can be subcutaneously injected is about 2 ml. Needles are generally 3/8 to 1 inch in length and 24 to 27 gauge.