Many urban legends are framed as complete stories with plot and characters. The compelling appeal of a typical urban legend is its elements of mystery, horror, fear or humor.Often they serve as cautionary tales.ecause people frequently allege that such tales happened to a  friend of a friend  (FOAF), the phrase has become a commonly used term when recounting this type of story. Sometimes urban legends are repeated in news stories, or distributed by e-mail or social media.
We have mast cells in the stomach wall. Somastatain-which is produced from d cells in the stomach wall is a known mast cell activator. We also know stress-in particular substance p and CRH also cause mast cells to spill contents. Histamine which we know is a chemical constantly released.
Most tissue histamine is found in granules in mast cells or basophils and its release is immunologic in function. Mast cells are especially numerous at sites of potential injury such as the nose, mouth, and feet, internal body surfaces and blood vessels.Basophils represent only 1% of circulating leukocytes.istamine. Histamines use in the body is not soley involved in allergic inflammatory response. The hormone/chemical transmitter histamine is a biogenic monoamine similar to serotonin, epinephrine and norepinephrine. Chemically histamine is 2-(4-imidazolyl)ethylamine and has the formula C5H9N3.