Collagen is an important protein that can be found throughout your body. In fact, it is found in all the connective tissues in your body ranging from your skin and bones, all the way down to your organs and blood vessels. Collagen functions several different ways in your body.
Upper gastrointestinal bleeding. Upper gastrointestinal bleeding (sometimes upper GI, UGI bleed, Upper gastrointestinal hemorrhage, gastrorrhagia) is gastrointestinal bleeding in the upper gastrointestinal tract, commonly defined as bleeding arising from the esophagus, stomach, or duodenum. Blood may be observed in vomit (hematemesis) or in altered form in the stool (melena).
It is estimated that UGIB accounts for 100â200 per 100,000 cases versus 20â27 per 100,000 cases for LGIB. Approximately 85% of lower gastrointestinal bleeding involves the colon, 10% are from bleeds that are actually upper gastrointestinal bleeds, and 3â5% involve the small intestines.