Biologics indicated for psoriasis work inside the body to target an overactive immune system, a possible cause of plaque psoriasis. When you talk to your dermatologist about plaque psoriasis treatment options, here are some things to think about: Once every 12 weeks (after 2 starter doses at weeks 0 and 4)
SKIP-BO(IPA: /skÉªpË-boÊ/) is a popular card game. In 1967, Ms. Hazel Bowman of Brownfield, Texas began producing a boxed edition of the game under the name Skip-bo. International Games, Inc. purchased the game in 1980. The company was subsequently bought by Mattel. It is a commercial version of the card-game Spite and Malice.
To play, you'll need a deck of Skip-Bo cards and at least two players, although you can play with up to six. The deck consists of 162 cards: 12 sets of 12 numbered cards and 18 Skip-Bo wild cards. The game is a variation on traditional card game Spite and Malice, which has similar rules but uses an ordinary playing card deck.