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Medical Definition of degenerative. : of, relating to, involving, or tending to cause degeneration degenerative conditions of the nervous systemâMorris Fishbein degenerative changes a degenerative muscle disorder.
Degenerative disc disease is the medical term used to describe symptoms of pain in the lower back that result from a weak disc in the spine. In addition to localized pain around the disc itself, the pain can also radiate to other parts of the body. Degenerative disc disease is caused by natural deterioration in the spine typically due to aging, or from an accident or injury. Degenerative disc disease is not really a disease; rather it is a medical condition that is presumed to get worse over time as the body ages.