The Mediterranean Sea is a large sea that is located between Europe, northern Africa and southwestern Asia. Its total area is 970,000 square miles (2,500,000 sq km) and its greatest depth is located off the coast of Greece at around 16,800 feet (5,121 m) deep.
3. Inflammation of the nodes: buboes; Lymph nodes can become cancerous tissues and metastesize. Other Lymphoid Organs. Spleen: Filters and purifies lymph nodes. (macrophages and lymphocytes in spleen fights bacteria, toxins and viruses, removes cellular debris). Distributes and recycles aged RBC);.
Macrophages also stimulate Lymphocytes and other immune cells that react to pathogens as what is called an antigen-presenting cell, also known as a histiocyte. Macrophages are located throughout the bloodstream, and may be fixed or they can be freely motile and capable of amoeboid-like movement. Definition of Macrophage and Its Role in the Body The best definition of macrophage is a white blood cell operating within the body tissues. 2  In humans, macrophages measure approximately 21 micrometers in diameter.