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Levothyroxine is the generic name for the synthetic form of thyroxine, a thyroid hormone replacement drug. This drug contains the synthetic form of one thyroid hormone, T4. Levothyroxine is the most commonly prescribed thyroid hormone replacement drug. Brand names in the U.S: Synthroid, Levothroid, Levoxyl, Unithroid.
Natural desiccated thyroid â sometimes abbreviated NDT â is a drug prepared from dried porcine (pig) thyroid glands. Natural desiccated thyroid was the only thyroid drug available in the early 1900s, under the brand name Armour Thyroid, until levothyroxine was introduced in the 1950s. Natural thyroid fell out of favor as the synthetic product was touted as more modern and stable.