The Mediterranean Sea is a large sea that is located between Europe, northern Africa and southwestern Asia. Its total area is 970,000 square miles (2,500,000 sq km) and its greatest depth is located off the coast of Greece at around 16,800 feet (5,121 m) deep.
3. Inflammation of the nodes: buboes; Lymph nodes can become cancerous tissues and metastesize. Other Lymphoid Organs. Spleen: Filters and purifies lymph nodes. (macrophages and lymphocytes in spleen fights bacteria, toxins and viruses, removes cellular debris). Distributes and recycles aged RBC);.
Macrophages can express paracrine functions within organs that are specific to the function of that organ. In the testis for example, macrophages have been shown to be able to interact with Leydig cells by secreting 25-hydroxycholesterol, an oxysterol that can be converted to testosterone by neighbouring Leydig cells.acrophages are highly specialized in removal of dying or dead cells and cellular debris. This role is important in chronic inflammation, as the early stages of inflammation are dominated by neutrophil granulocytes, which are ingested by macrophages if they come of age (see CD31 for a description of this process).