Drugs versus Biologics. 1  A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.enerics Drugs versus Follow-On Biologics. 1  To be approved as a generic, a drug must have the same active ingredient, strength, dosage form, and route of administration as the reference drug, and it must also be bioequivalent..
Viruses (e.g., adenovirus, astrovirus, rotavirus, Norwalk virus) are the most common cause of diarrhea in the United States. The most common ones in children are rotavirus and in adults are norovirus. Escherichia coli, Clostridium difficile, and Campylobacter, Salmonella, and Shigella spp. are common bacterial causes.
Bacterial infections cause the more serious cases of diarrhea. Typically, infection with bacteria occurs after eating contaminated food or drinks (food poisoning). Bacterial infections also cause severe symptoms, often with vomiting, fever, and severe abdominal cramps or abdominal pain. Bowel movements occur frequently and may be watery and individuals may experience explosive diarrhea which is a very forceful, almost violent, expulsion of loose, watery stool along with gas.