Freebase (0.00 / 0 votes) Rate this definition: Chelo. Jose Oscar Mejias Hernandez, better known as Chelo, is a hip-hop and pop singer based in Miami Beach, Florida recently signed with Sony BMG as a solo artist. His debut album is called 360Â°, and fuses pop, urban and Latin music. The album is recorded in Spanglish. He is of Puerto Rican descent.
C-reactive protein (CRP) is a protein produced by the liver and found in the blood. C-reactive protein is not normally found in the blood of healthy people. It appears after an injury, infection, or inflammation and disappears when the injury heals or the infection or inflammation goes away.
C-reactive protein is an annular, pentameric protein found in blood plasma, whose levels rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells in order to activate the complement system via C1q. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes). It is a member of the pentraxin family of proteins. It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.