While ALS is the most common motor neuron disease, we also treat all other forms, including: 1  PLS (Primary Lateral Sclerosis), affecting the upper motor neurons in the brain and spinal cord. 2  PMA (Primary Muscular Atrophy), affecting the lower motor neurons from the spine to the muscle.
Deletion Mutation and DNA. A deletion mutation occurs when part of a DNA molecule is not copied during DNA replication. This uncopied part can be as small as a single nucleotide or as much as an entire chromosome.The loss of this DNA during replication can lead to a genetic disease.eletion Mutation and DNA. A deletion mutation occurs when part of a DNA molecule is not copied during DNA replication. This uncopied part can be as small as a single nucleotide or as much as an entire chromosome.
Deletion on a chromosome. In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Î´) is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is lost during DNA replication.Any number of nucleotides can be deleted, from a single base to an entire piece of chromosome. ' Terminal Deletion' â a deletion that occurs towards the end of a chromosome. 2  Intercalary Deletion / Interstitial Deletion â a deletion that occurs from the interior of a chromosome. 3  Microdeletion â a relatively small amount of deletion (up to 5Mb that could include a dozen genes).