Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes and extra fluid from the blood to form urine. Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. 2  Autosomal dominant PKD is the most common inherited form while autosomal recessive PKD is a rare.
Alabama's Mountain Region contains the state's largest lake: Lake Guntersville. Cradled in the Appalachian foothills of northern Alabama, Lake Guntersville is located between Bridgeport and Guntersville, stretching out over 75 miles into Tennessee (near Chattanooga) and occupying 69,000 acres.
Among Largest Man-Made Lakes, with 750 Miles of Shoreline. One of the largest man-made lakes in the country, Lake Martin covers 44,000 acres with more than 750 miles of wooded shoreline in Tallapoosa, Elmore and Coosa counties of east central Alabama. Lake Martin is known for its clear water, gorgeous landscape, along with many interesting islands and unique rock formations.