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DRUG DESCRIPTION. WELLBUTRIN XLÂ® (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.
Wellbutrin Withdrawal Stopping Wellbutrin Â® (bupropion hydrochloride) abruptly can lead to withdrawal symptoms. Although the manufacturer does not warn about the possibility of withdrawal from Wellbutrin, it is possible that withdrawal symptoms may occur.