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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
Zoloft, an oral antidepressant pill made of compressed crystalline powder, is usually prescribed to first-time users in a 50-milligram-per-day dose for depression and PMDD and 25 milligrams per day for other disorders. Dosages can be increased with time and medical supervision up to 200 milligrams per day. It's also available in liquid form [source: RX List]. Within just a few hours of taking an SSRI for the first time, the levels of serotonin in the brain and bloodstream increase. Yet, we don't feel immediate results.