Biologics indicated for psoriasis work inside the body to target an overactive immune system, a possible cause of plaque psoriasis. When you talk to your dermatologist about plaque psoriasis treatment options, here are some things to think about: Once every 12 weeks (after 2 starter doses at weeks 0 and 4)
SKIP-BO(IPA: /skÉªpË-boÊ/) is a popular card game. In 1967, Ms. Hazel Bowman of Brownfield, Texas began producing a boxed edition of the game under the name Skip-bo. International Games, Inc. purchased the game in 1980. The company was subsequently bought by Mattel. It is a commercial version of the card-game Spite and Malice.
You get one point for each of your team's stones that is closer to the button than your opponent's. There are 10 ends in each game of curling. The team with the most total points wins. Easy, right? Hardly. Despite its simple appearance, curling is a game of complex strategy and strict team member roles. The captain of a curling team is called the skip. The skip usually throws last, because the final stones of each end are the most decisive when it comes to points. Before the skip throws, he or she stands behind the house and directs the other team members' throws, whether to attempt a draw â landing the stone inside the house â or a hit, knocking an opponent's stone out of play.