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Fluid-mosaic model. 1  Plasma membrane consists of a phospholipid bilayer studded with proteins, polysaccharides, lipids. 2  The lipid bilayer is semipermeable Regulates passage of substances into and out of the cell. H2O and some small, uncharged, molecules (O2, CO2) can pass through.
Epithelial cells of many organs and tissues that produce mucus, sweat, saliva, tears and digestive enzymes have a gene Cystic Fibrosis Trans-membrane Conductance Regulator (CFTR). The CFTR protein functions as a channel for the movement of chloride ions in and out of the cells.