Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes and extra fluid from the blood to form urine. Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. 2  Autosomal dominant PKD is the most common inherited form while autosomal recessive PKD is a rare.
Alabama's Mountain Region contains the state's largest lake: Lake Guntersville. Cradled in the Appalachian foothills of northern Alabama, Lake Guntersville is located between Bridgeport and Guntersville, stretching out over 75 miles into Tennessee (near Chattanooga) and occupying 69,000 acres.
1 Oconee River - 221 miles (356 km). 2  The Flint River is the longest river entirely within Georgia. 3  It has its source in Atlanta, and it is one of the sources of the Appalachicola River in Florida. Oswegatchie River - 137 miles (220 km). 2  Black River â 125 miles (201 km). 3  The Hudson River is the longest river that is entirely within New York, though it also forms part of the state's boundary with the State of New Jersey.