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Lipase is a digestive enzyme produced by the following organs: pancreas (pancreatic lipase), liver (hepatic lipase), and stomach (stomach/gastric lipase). Enzymes are responsible for the metabolism of carbohydrates, proteins, and fats.
What is well known at a lower level is pancreatic lipase which is secreted into the small intestine (duodenum). It originates in the pancreas but works in the small intestine. lipase is produced in the pancreas and is secreted by the small intestine. In the Small Intestine, Carbohydrase, Protease and Lipase is found, but Lipid is formed into fatty acids and glycerol by the way. So main answer from me: Small Intestine. lipase as well as many proeteases, carbohydrases, and nucleases are primarily produced in the pancrease and secreted into the small intestines.