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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
Prescriptions for Zoloft. Physicians usually start their patients on a relatively low sertraline dosage, typically 25 to 50 mg daily. They might eventually increase this dosage up to 200 mg, but low starting dosages are the norm.