Points to consider prior to initiating RETROVIR in pregnant women for the prevention of maternal-fetal HIV-1 transmission include: â¢ In most cases, RETROVIR for prevention of maternal-fetal HIV-1 transmission should be given in combination with other antiretroviral drugs. â¢ Prevention of HIV-1 transmission in women who have received RETROVIR for a prolonged period before pregnancy has not been evaluated.
Vancomycin is an antibiotic drug used to treat serious, life-threatening infections by gram-positive bacteria that are resistant to less-toxic agents. The reference range for vancomycin trough levels is 10-20 Âµg/mL (15-20 Âµg/mL for complicated infections). The reference range for vancomycin peak levels is 25-50 Âµg/mL. Next. Vancomycin trough concentrations below 10 Âµg/mL are associated with inadequate therapy and an increased risk of developing bacterial resistance. Vancomycin trough concentrations above the therapeutic range may increase the risk of nephrotoxicity.
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