22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
Bibbidi-Bobbidi-Boo (also called The Magic Song) is a novelty song, written in 1949 by Al Hoffman, Mack David, and Jerry Livingston. It was introduced in the 1950 film Cinderella, performed by actress Verna Felton. Ilene Woods and The Woodsmen with Harold Mooney and His Orchestra recorded it in Hollywood on October 26, 1949.