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VERY DIFFERENT: Parkinson's is disease of misfolded protein usually occurring in older males, associated with tremor, stiffness, loss of balance, etc. Multiple sclerosis is an autoimmune mediated disorder of people in their 20's and 30's, occas in childhood, and typically a pattern of ...Read more.
Many symptoms of Parkinson's disease involve motor control, the four most common categories being: Rigidity. Rigidity, or resistance to movement, affects most patients and usually begins in the legs or neck. The affected muscles will remain tense and contracted, and some patients may feel pain as well as stiffness. Attempting to move the limb of a patient in Rigidity may lead to short, jerky movements called 'cog-wheeling'.