therefore. sentence connector. 1. thus; hence: used to mark an inference on the speaker's part: those people have their umbrellas up: therefore, it must be raining. 2. consequently; as a result: they heard the warning on the radio and therefore took another route.
Statins come in tablet or capsule form. They are taken once or twice a day, depending on the particular product. Short-acting statins must be taken in the evening (near bedtime), while long-acting statins can be taken at any time of the day. Either way, make sure to take your dose at the same time each day. Some statins can be taken with or without food; others must be taken with food.
This is because the hepatic synthetic activity is maximum at night. Hence statins have maximum efficiency in decreasing cholesterol when given at night. This is especially important in statins with short half life such as simvastatin. Newer statins like atorvastatin have a longer half life. Other drugs which block the hepatic synthetic function (eg: warfarin which blocks hepatic synthesis of clotting factors) are also best given at night time.