Changes with Age. In most cases, a person's normal respiratory rate will change with age; younger adults, children, and babies will typically have faster respiratory rates, because as people age, their breathing usually slows down.
Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.
Divestopedia explains Material Adverse Change (MAC) Material adverse change is applicable to substantial changes in business conditions or prospects of the firm being funded or acquired. Material changes may include any aspect of the firm as well as its subsidiaries, including: Liabilities and assets.