anything done or to be done; anything requiring action or effort; business; concern: an affair of great importance. 2. affairs, matters of commercial or public interest or concern; the transactions of public or private business or finance:
Hyperlactatemia is defined as a persistent, mild to moderate (2-4 mmol/L) increase in blood lactate concentration without metabolic acidosis, whereas lactic acidosis is characterized by persistently increased blood lactate levels (usually >5 mmol/L) in association with metabolic acidosis.
Interpretation Provides information to assist in interpretation of the test results. Marked elevations in lactate dehydrogenase (LD) activity can be observed in megaloblastic anemia, untreated pernicious anemia, Hodgkin's disease, abdominal and lung cancers, severe shock, and hypoxia.