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nodule - (mineralogy) a small rounded lump of mineral substance (usually harder than the surrounding rock or sediment) mineralogy - the branch of geology that studies minerals: their structure and properties and the ways of distinguishing them.
nodule. noun. 1  A small knotlike protuberance. 2  Medicine A small, abnormal but usually benign mass of tissue, as on the thyroid gland, in the lung, or under the skin. 3  Botany A small knoblike outgrowth, especially one on the roots of a leguminous plant that contains bacteria that fix nitrogen.