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Nephrotic syndrome is characterized by large proteinuria (>3.5 g per 1.73 m2 body surface area per day, or > 40 mg per square meter body surface area per hour in children), hypoalbuminemia (< 2,5 g/dl), hyperlipidaemia, and edema (which is generalized and also known as anasarca or dropsy) that begins in the face.
1 All CRF patients with the exception of those with medullary cystic kidney disease have fixed proteinuria (>200 mg/24 hours).  The syndrome may also come to attention because of an elevated BUN or serum creatinine concentration in laboratory testing done for a variety of reasons.