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Researchers have determined that Werner Syndrome is caused by abnormal changes (mutations) of a gene (known as the WRN gene) located on the short arm of chromosome 8 (8p12-11.2).* More than 80 different mutations of the WRN gene have been identified in individuals with the disorder.ymptoms of the following disorders can be similar to those of Werner Syndrome. Comparisons may be useful for a differential diagnosis: Hutchinson-Gilford Progeria Syndrome is a very rare disorder of childhood characterized by premature aging, short stature, and characteristic facial features.
Autism, rheumatoid arthritis, periodontal disease, chronic fatigue syndrome, Crohn's disease and colitis stem from the inflammation triggered by a leaky gut. Malabsorption of nutrients, candida and parasitic infections along with food sensitivities and allergies are also connected with this syndrome.