Today's true sports drinks are still the classic Gatorade -- packed with the electrolytes potassium, magnesium, calcium, and sodium to provide energy during intense workouts -- as well as competitors such as Cytomax, Allsport, and Accelerade.
Certain medications can also cause Charley horse as a result of their side effects. Drugs such as statins or medicines prescribed for lowering cholesterol, blood pressure, diuretics, asthma medicines like terbutaline and salbutamol, morphine and lithium can trigger muscle spasms.
1 In most of the cases, Charlie horses are the late responses of overstraining a muscle during exercise, or otherwise. 2  Charley horse might be the result of an electrolyte or mineral imbalance in the body.  In some of the cases, Charlie horses have been found to be a signal of the onset of a vascular disease.