Changes with Age. In most cases, a person's normal respiratory rate will change with age; younger adults, children, and babies will typically have faster respiratory rates, because as people age, their breathing usually slows down.
Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.
Modic changes were first described and separated into 3 different types of changes by Dr. Michael Modic in 1988. Normal bone consists of an internal scaffolding of bone, called trabeculae. In the hollows between the trabeculae is red bone marrow, which produces blood cells.