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What is the normal respiratory frequency? Medical textbooks suggest that the normal respiratory rate for adults is only 12 breaths per minute at rest. Older textbooks often provide even smaller values (e.g., 8-10 breaths per minute). Most modern adults breathe much faster (about 15-20 breaths per minute) than their normal breathing frequency.
Normal respiration is driven mostly by the levels of carbon dioxide in the arteries, which are detected indirectly by central chemoreceptors when carbon dioxide crosses the bloodâbrain barrier, forming detectable Hydrogen ions, and directly by peripheral chemoreceptors, and very little by the oxygen levels.his increases as the PaO 2 goes to 70 torr and below, while hypoxic drive is no longer active when PaO 2 exceeds 170 torr. The hypoxic drive is so weak that unconsciousness will develop before respiratory distress is noted and is therefore a risk for pilots flying at high altitudes.