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â¢ Mitochondrial DNA is found inside the mitochondria while nuclear DNA is found inside the nucleus of a cell. â¢ One cell contains approximately 99.75% of nuclear DNA and 0.25% of mitochondrial DNA.â¢ The mutation rate of mitochondrial DNA is nearly twenty times faster than that of nuclear DNA.he uniqueness of mitochondrial DNA is that it is maternally inherited as a linked set of genes, passed on to progeny in the cytoplasm of the egg cell; thus no recombination between maternal and paternal genomes occurs.
The nucleus contains the chromosomes of the cell. The main genome of the organism is found in the nucleus. In humans, the nucleus holds 46 chromosomes, which contains about 25,000 genes. However, mitochondria have DNA of their own.The human mitochondrion has DNA in the form of plasmids, which are circular pieces of DNA. Mitochondrial genes encode for 13 proteins and 24 RNA molecules that are only found in the mitochondrion.he nucleus contains the chromosomes of the cell. The main genome of the organism is found in the nucleus. In humans, the nucleus holds 46 chromosomes, which contains about 25,000 genes. However, mitochondria have DNA of their own.