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â¢ Mitochondrial DNA is found inside the mitochondria while nuclear DNA is found inside the nucleus of a cell. â¢ One cell contains approximately 99.75% of nuclear DNA and 0.25% of mitochondrial DNA.â¢ The mutation rate of mitochondrial DNA is nearly twenty times faster than that of nuclear DNA.he uniqueness of mitochondrial DNA is that it is maternally inherited as a linked set of genes, passed on to progeny in the cytoplasm of the egg cell; thus no recombination between maternal and paternal genomes occurs.
Confidence votes 68. Nuclear DNA, which is found in the nucleus, is inherited from both parents. On the other hand, mtDNA is found in the mitochondria and, in most multicellular organisms, is inherited from the maternal lineage.Nuclear DNA is arranged in linearly organized chromosomes while mtDNA is organized as a circular chromosome.onfidence votes 68. Nuclear DNA, which is found in the nucleus, is inherited from both parents. On the other hand, mtDNA is found in the mitochondria and, in most multicellular organisms, is inherited from the maternal lineage.