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â¢ Mitochondrial DNA is found inside the mitochondria while nuclear DNA is found inside the nucleus of a cell. â¢ One cell contains approximately 99.75% of nuclear DNA and 0.25% of mitochondrial DNA.â¢ The mutation rate of mitochondrial DNA is nearly twenty times faster than that of nuclear DNA.he uniqueness of mitochondrial DNA is that it is maternally inherited as a linked set of genes, passed on to progeny in the cytoplasm of the egg cell; thus no recombination between maternal and paternal genomes occurs.
DNA has thymine as one of the two pyrimidines while mRNA has uracil as its pyrimidines base. DNA is present in the nucleus while mRNA diffuses into the cytoplasm after synthesis. DNA is double-stranded while mRNA is single-stranded. mRNA is short-lived while DNA has a long lifespan.oth of these have structural and functional differences between them. DNA. DNA or deoxyribonucleic acid is the basic genetic material of major life forms except the plant viruses, bacteriophage, and a few other viruses in which either the DNA is absent or any variation of the double-stranded DNA is present.