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For example, a human cell has 46 chromosomes. In the karyotype, 23 pairs of chromosomes will be shown (23 x 2 = 46). A karyotype can show different types of mutations, depending on which chromosome it affects.For example, Down Syndrome is a trisomy in chromosome 21, so there will be THREE instead of two chromosome 21s. You can research more mutations shown by chromosomes in a karyotype.or example, a human cell has 46 chromosomes. In the karyotype, 23 pairs of chromosomes will be shown (23 x 2 = 46). A karyotype can show different types of mutations, depending on which chromosome it affects.
Point Mutations. Point mutations are the most common type of gene mutation. Also called a base-pair substitution, this type of mutation changes a single nucleotide base pair. Silent Mutation: Although a change in the DNA sequence occurs, this type of mutation does not change the protein that is to be produced. This is because multiple genetic codons can encode for the same amino acid. Amino acids are coded for by three nucleotide sets called codons.