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How to Take PRISTIQ. Most people start with a once-daily 50-mg dose of PRISTIQ (taken with or without food). Your doctor may keep you on your starting dose throughout your treatment.Talk to your doctor about any health conditions you may have, as your dose might be affected.PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.our doctor may keep you on your starting dose throughout your treatment. Talk to your doctor about any health conditions you may have, as your dose might be affected. PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.
Standard Adult Pristiq Dosage. The starting dosage for Pristiq for adults is 50 mg once daily to be taken with or without food. This goes for all medical conditions that the drug is intended to treat.Sometimes, the dose may be increased up to 400mg, although there is no proof that a higher dose can bring more benefits.In fact, taking more than 50 mg per day of Pristiq may be dangerous as it has been associated with effects that are more adverse than therapeutic.ometimes, the dose may be increased up to 400mg, although there is no proof that a higher dose can bring more benefits. In fact, taking more than 50 mg per day of Pristiq may be dangerous as it has been associated with effects that are more adverse than therapeutic.