A regulatory framework Although common in other process manufacturing industries (e.g., food and chemicals), continuous processing is at a nascent stage in the pharmaceutical industry, where batch manufacturing is the prevailing mode.
When the motor neurons in the brainstem are affected (bulbar ALS), the muscles used in speech and swallowing are impaired. ALS only affects muscles that are moved voluntarily (such as those in the mouth or arm) and does not impact those muscles involved in involuntary movements, such as digestion.
ALS, sometimes called Lou Gehrig's disease, is a progressive brain disease that attacks the nerve cells that control muscles (motor neurons). It results in the gradual degeneration and death of motor neurons that are located in the brain, brainstem, and spinal cord.