22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
In a Nutshell. âSummertime,â the first song in George Gershwinâs folk opera Porgy and Bess, is a simple lullaby. The songâs history, on the other hand, has been anything but simple. Porgy and Bess has had an even more complicated history. Written in 1935, it has been labeled a classic by some and a racist minstrel show by others.