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Inhibitors are a serious medical problem that can occur when a person with hemophilia has an immune response to treatment with clotting factor concentrates. The immune system defends the body from harmful germs and viruses.
A class of chemicals that interrupt the proper binding of substrates to enzymes are known as inhibitors. They either slow down the process, or they can stop it altogether. Inhibitors in the enzymeâs environment can change its shape so that a substrate no longer fits to it, a process called noncompetitive inhibition.