Medical Definition of IMMUNOASSAY. : a technique or test (as the enzyme-linked immunosorbent assay) used to detect the presence or quantity of a substance (as a protein) based on its capacity to act as an antigen or antibody.â immunoassay transitive verb. â imÂ·muÂ·noÂ·asÂ·sayÂ·able \-a-ËsÄ-É-bÉl\ adjective.efinition of IMMUNOASSAY. : a technique or test used to detect the presence or quantity of a substance (as a protein) based on its capacity to act as an antigen. â imÂ·muÂ·noÂ·asÂ·sayÂ·able \-a-ËsÄ-É-bÉl\ adjective. ADVERTISEMENT. noun imÂ·muÂ·noÂ·asÂ·say \Ëim-yÉ-nÅ-Ëas-ËÄ, im-Ëyue-ËyÃ¼-, -nÅ-a\. ËsÄ
Signs and symptoms of Parkinson's disease. Signs and symptoms of Parkinson's disease are varied. Parkinson's disease affects movement, producing motor symptoms. Non-motor symptoms, which include dysautonomia, cognitive and neurobehavioral problems, and sensory and sleep difficulties, are also common. When other diseases mimic Parkinson's disease they are categorized as Parkinsonism.
The symptoms of Parkinson's disease result from the loss of pigmented dopamine-secreting (dopaminergic) cells in the pars compacta region of the substantia nigra These neurons project to the striatum and their loss leads to alterations in the activity of the neural circuits within the basal ganglia that regulate movement, an inhibition of the direct pathway and excitation of the indirect pathway.