Bulging Disc Definition. Herniated Disc Video. A bulging disc is a condition in which the nucleus (inner portion) of a spinal disc remains contained within the annulus fibrosus (outer portion), unlike a herniated disc in which the nucleus leaks out of the disc.erniated Disc Video. A bulging disc is a condition in which the nucleus (inner portion) of a spinal disc remains contained within the annulus fibrosus (outer portion), unlike a herniated disc in which the nucleus leaks out of the disc.
The term broad-spectrum antibiotic refers to an antibiotic that acts against a wide range of disease-causing bacteria. A broad-spectrum antibiotic acts against both Gram-positive and Gram-negative bacteria, in contrast to a narrow-spectrum antibiotic, which is effective against specific families of bacteria. An example of a commonly used broad-spectrum antibiotic is ampicillin.
Toxicity increased by NSAIDs, salicylates, phenytoin, sulfonylureas, sulfonamides, probenecid, folic acid antagonists. May be potentiated by penicillins (monitor), tetracyclines, chloramphenicol, non-absorbable broad spectrum antibiotics. May be antagonized by folic acid. May potentiate theophylline, mercaptopurine.