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Side Effects of L-arginine Hydrochloride For most people, taking L-arginine hydrochloride is thought to be relatively safe. Possible side effects of using L-arginine HCL capsules or powder include bloating, diarrhea, abdominal pain, gout, abnormalities in blood circulation, low blood pressure, inflammation of the lungs and airways, allergies and worsening of asthma symptoms. High-doses of L-arginine may be potentially fatal in children.
One of the most severe potential side effects of L-arginine is anaphylaxis [source: Mayo Clinic]. That's a very severe allergic reaction that can result in shock and potentially even death. In an anaphylactic reaction, you may experience sudden chills, sweating, tremors, hives, vomiting, and diarrhea, shortness of breath and light-headedness or fainting -- all at once.