You also need. to know if the pilot wants to combine the flight review with a new endorsement or. aircraft checkout. Offer an initial estimate of how much time to plan for ground and. flight training. How much time is âenoughâ will vary from pilot to pilot. Someone who. flies the same airplane 200 hours every year may not need as much time as someone. who has logged only 20 hours since the last flight review, or a pilot seeking a new. endorsement in conjunction with the flight review.
Grapefruit products, such as grapefruit, grapefruit juice, or grapefruit supplements, can interact with some cholesterol-lowering statins and increase the level of medication in your blood. LipitorÂ® (atorvastatin calcium) is one of these statins.
More than 85 medications are known to interact with grapefruit juice, and approximately one-half of these interactions have the potential to cause serious adverse events. In addition, many medications can interact with other juices, such as orange, apple, and cranberry.ince grapefruit primarily targets intestinal CYP3A4, not liver CYP3A4, I.V. medications are usually not affected. Grapefruit products also interact with the efflux transporter P-glycoprotein and uptake transporters such as organic anion-transporting polypeptides (OATPs).