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A molecule is the smallest particle in a chemical element or compound that has the chemical properties of that element or compound. Molecules are made up of atom s that are held together by chemical bonds.or example, O 2 is the oxygen molecule most commonly found in the earth's atmosphere; it has two atoms of oxygen. However, under certain circumstances, oxygen atoms bond into triplets (O 3), forming a molecule known as ozone.
Full Definition of MOLECULE. 1. : the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms. 2.: a tiny bit: particle.See molecule defined for English-language learners.See molecule defined for kids. ADVERTISEMENT. the smallest possible amount of a particular substance that has all the characteristics of that substance. : a very small amount of something.