Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
Think of a diode as a one-way street for electricity. When the diode is in forward bias, the diode allows traffic, or current, to flow from the anode, towards the cathode leg. In a reverse bias current is blocked so there is no flow of electricity through the circuit.hen the voltage across the diode is positive, a lot of current can flow once the voltage becomes large enough. When the voltage across the diode is negative, virtually no current flows. 1  N-type: With N-type doping, phosphorus or arsenic is added, in parts per billion, to the silicon in small quantities.