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While spaying is traditionally recommended for kitties between 4 and 6 months of age, spaying as young as 8 weeks old is considered safe, according to Cat Channel. Many animal shelters actually spay kitties prior to adopting them out at this age.
Best Answer: A good rule of thumb is to have your kittens spayed and neutered at six months. (The five pound weight requirement correlates.) There is a link between neutering a male before the age of six months to an increase in the likelihood that he will develop kidney/urinary tract disease.