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In its early stages, some of the symptoms of ALS can be similar to those of MS. These include: Stiff, weak muscles; Twitching or spasms; Fatigue; Trouble walking; If youâre having these symptoms, donât try to guess what's going on. See a doctor and get a diagnosis. As ALS attacks the nerves that deal with movement, your symptoms will get worse.
MOTOR NEURON DISEASES. Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative disorder of upper and lower motor neurons. Lower motor neuron loss causes muscle weakness, atrophy, and fasciculations; upper motor neuron involvement causes spasticity, clonus, hyperactive tendon reflexes, and Babinski signs.Dementia appears at the onset or develops later in a significant proportion of ALS patients.ower motor neuron loss causes muscle weakness, atrophy, and fasciculations; upper motor neuron involvement causes spasticity, clonus, hyperactive tendon reflexes, and Babinski signs. Dementia appears at the onset or develops later in a significant proportion of ALS patients.