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Other diseases which cause dry mouth, not only during the night but during the day as well â these are viral and bacterial infections and Sjogrenâs syndrome, all of which have an influence on the flow of saliva. If an individual is undergoing radiation therapy or hemodialysis, these also cause severe dry mouth.
There are several causes of dry mouth at night that are purely physical. Aging can slow the production of saliva, as can certain cancers. One of the first symptoms of both diabetes and Sjogren's Syndrome is dry mouth, and nerve damage can also cause this condition.