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While spaying is traditionally recommended for kitties between 4 and 6 months of age, spaying as young as 8 weeks old is considered safe, according to Cat Channel. Many animal shelters actually spay kitties prior to adopting them out at this age.
Best Answer: For female, sexual maturity can be as soon as 4 months old. For male, the normal age is between 5-6 months of age. Therefore, it will be very important to neuter your kittens before that. Early spay and neuter can be performed at the age of 8 weeks old or when they weigh at least 2 lbs. There are no side effects with early spay and neuter and does not cause any development of behavioral problems later on. Cats are opportunist breeder. They can mate with any other cats, mother son, father daughter, brother and sisters.