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While spaying is traditionally recommended for kitties between 4 and 6 months of age, spaying as young as 8 weeks old is considered safe, according to Cat Channel. Many animal shelters actually spay kitties prior to adopting them out at this age.
Both male and female kittens can be spayed as early as 10-12 weeks of age, although this varies somewhat from vet to vet. Cats usually reach sexual maturity around six months â¦old and some even younger at four months, so it is best to spay kittens before that age.