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Other diseases which cause dry mouth, not only during the night but during the day as well â these are viral and bacterial infections and Sjogrenâs syndrome, all of which have an influence on the flow of saliva. If an individual is undergoing radiation therapy or hemodialysis, these also cause severe dry mouth.
Dry Mouth Causes. There are many causes of dry mouth, such as not drinking enough liquid during the day, smoking, and sleeping with your mouth open, among others. Dry mouth can also be caused by certain types of medication, such ADHD medicine, anti-histamines, antidepressants, sleep medications, and narcotics.