Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
The Fund seeks to track the performance of a benchmark index that measures the investment return of mid-capitalization stocks. The Fund employs a passive management approach designed to track the performance of the CRSP US Mid Cap Index, a broadly diversified index of stocks of medium-size U.S. companies.