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Long-term treatment with ibuprofen at a dose of 1200 mg/day does not increase the risk of renal impairment in elderly people (Griffin et al, 2000). Ibuprofen is associated with a low risk of renal toxicity in overdose (Jenkinson et al, 1988; Volans and Fitzpatrick, 1999).
Ibuprofen is an NSAID (non-steroidal anti-inflammatory drug) that is commonly used for the relief of symptoms of arthritis, fever, primary dysmenorrhea (menstrual pains), and as an analgesic (a medication given to reduce pain without resulting in loss of consciousness).