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If you are on a standard 2,000-calorie diet, this means that you should be eating no more than 500 calories from sugar, or 125 grams. Like all carbohydrates, sugar contains 4 calories per gram. The USDA recommendations are lower than the IOM's.
As a general guideline, women may need to reduce their daily intake of sugar to 17 grams a day while men may need to do the same and bring down their sugar consumption to 25 grams per day. If the diet needs to be customized, their doctor can help specify a target for their daily sugar intake.