Disclaimers: This article explains what an FHA underwriter looks for during the loan review process. This is a general overview of events and does not include every possible underwriting scenario. Every mortgage situation is different because every borrower is different.
DIRECT GENETIC TESTING. Huntingtonâs disease has become a model for genetic testing in other adult-onset inherited disorders because the illness is relatively common, and there is widespread experience with it. Genetic testing programs began in 1986 with linkage testing and evolved to direct gene testing shortly after the gene was cloned in 1993.
Humans have 46 chromosomes (23 pairs). The faulty gene that causes Huntington's disease is found on chromosome number four. The normal copy of the gene produces a protein called huntingtin, but the faulty gene contains an abnormal region of what are called CAG repeats.This area is larger than normal and produces a mutant form of huntingtin.nheriting Huntington's disease. A parent with the Huntington's disease gene has one good copy of the gene and one faulty copy. Their child will inherit one of these genes. Therefore, there's a 50:50 chance that the child will get the faulty gene and develop Huntington's disease.