Disclaimers: This article explains what an FHA underwriter looks for during the loan review process. This is a general overview of events and does not include every possible underwriting scenario. Every mortgage situation is different because every borrower is different.
DIRECT GENETIC TESTING. Huntingtonâs disease has become a model for genetic testing in other adult-onset inherited disorders because the illness is relatively common, and there is widespread experience with it. Genetic testing programs began in 1986 with linkage testing and evolved to direct gene testing shortly after the gene was cloned in 1993.
Huntingtonâs disease is caused by a mutation in the gene for a protein called huntingtin. The defect causes the cytosine, adenine, and guanine (CAG) building blocks of DNA to repeat many more times than is normal. Each child of a parent with HD has a 50-50 chance of inheriting the HD gene.