Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
For plenty of reactions, however, the forward reaction is so favored, and the reverse reaction is so negligible, that reactions are written simply in terms of the solid forward arrow, $A\rightarrow B$. However, we will now consider forward/reverse reaction pairs that exist in chemical equilibrium with one another. In a chemical reaction, chemical equilibrium is the state in which the forward reaction rate and the reverse reaction rate are equal. The result of this equilibrium is that the concentrations of the reactants and the products do not change.