Following are the types of sales people in organizations: 1  The Diplomat As the name suggests, a diplomat is one who always tries to play a safe game. 2  The Rejection Dreader Such sales professionals fear rejections and failures at work.
A phosphodiester bond occurs when exactly two of the hydroxyl groups in phosphoric acid react with hydroxyl groups on other molecules to form two ester bonds. Phosphodiester bonds are central to all life on Earth, as they make up the backbone of the strands of nucleic acid. In DNA and RNA, the phosphodiester bond is the linkage between the 3' carbon atom of one sugar molecule and the 5' carbon atom of another, deoxyribose in DNA and ribose in RNA. Strong covalent bonds form between the phosphate group and two 5-carbon ring carbohydrates (pentoses) over two ester bonds. The phosphate groups in the phosphodiester bond are negatively charged. Because the phosphate groups have a pKa near 0, they are negatively charged at pH 7.
While each hydrogen bond is extremely weak (compared to a covalent bond for example), the millions of H-bonds together represent an extremely strong force that keeps the two DNA strands together.eoxyribonucleic acid, or DNA, is a polymer of nucleotides linked together by specific bonds known as phosphodiester bridges. The phosphate group (PO3) of one nucleotide links to the hydroxyl group (OH) of the following nucleotide. Hundreds of millions of these linkages occur within the DNA polymer.