Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
If the forward current through the diode is near the maximum the diode is designed for, it typically has an RF resistance of only 0.1 ohm, and thus acts as a closed switch. Thus, for RF, the PIN diode acts as a closed switch if it is forward biased with the near maximum DC bias current.