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What to do about a droopy brow or eyelid. The effect of the Botox will last about three to four months. That is a long time to go around looking droopy on one side, but there are some options available to improve the situation.
When the muscle can no longer contract, the wrinkles soften and relax. Typical onset of Botox is between 24 and 72 hours, although some patients may require up to 5 days to see a result. The maximal effect of Botox occurs at about 10 days after treatment.