A regulatory framework Although common in other process manufacturing industries (e.g., food and chemicals), continuous processing is at a nascent stage in the pharmaceutical industry, where batch manufacturing is the prevailing mode.
When the motor neurons in the brainstem are affected (bulbar ALS), the muscles used in speech and swallowing are impaired. ALS only affects muscles that are moved voluntarily (such as those in the mouth or arm) and does not impact those muscles involved in involuntary movements, such as digestion.
Amyotrophic lateral sclerosis (ALS) ALS affects both your upper and lower motor neurons. With ALS, you gradually lose control over the muscles that help you walk, talk, chew, swallow, talk, and breathe. Over time, they weaken and waste away. You may also have stiffness and twitches in your muscles.