22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
Happy Birthday Darlin'. Happy Birthday Darlin' is a song written by Chuck Howard, and recorded by American country music artist Conway Twitty. It was released in October 1979 as the third and final single from his album Cross Winds. Happy Birthday Darlin' was Conway Twitty's 23rd number one on the country chart as solo artist.