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In its early stages, some of the symptoms of ALS can be similar to those of MS. These include: Stiff, weak muscles; Twitching or spasms; Fatigue; Trouble walking; If youâre having these symptoms, donât try to guess what's going on. See a doctor and get a diagnosis. As ALS attacks the nerves that deal with movement, your symptoms will get worse.
4 stages of ALS disease. When the upper motor neurons face a serious problem such as degeneration, this causes spastic, also known as muscle contraction or tightening. Whereas, the effects on the lower motor neurons cause loss in the ability to move, muscle shrinkage, twitching, and weakness in the muscles as well.