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Long-term treatment with ibuprofen at a dose of 1200 mg/day does not increase the risk of renal impairment in elderly people (Griffin et al, 2000). Ibuprofen is associated with a low risk of renal toxicity in overdose (Jenkinson et al, 1988; Volans and Fitzpatrick, 1999).
If youâre tempted to take a daily ibuprofen to extend your life because theyâre cheap and readily available â donât! Ibuprofen, while safe enough for human consumption, is not risk-free. As with most drugs it can cause side effects, including gastrointestinal bleeding.