1 Globally, an estimated 350 million people of all ages suffer from depression. 2  Depression is the leading cause of disability worldwide, and is a major contributor to the overall global burden of disease. 3  More women are affected by depression than men.  At its worst, depression can lead to suicide.
Low-temperature cooking. Low-temperature cooking is a cooking technique using temperatures of 45 to 85 Â°C (113 to 185 Â°F) for a prolonged time to cook food.
In most cases, the meat will be fork tender. However, use a meat thermometer to determine the meat's doneness, which should register 145 degrees Fahrenheit for medium rare and 160 degrees for medium. Remove the roast from the slow cooker and allow the meat to rest 10 minutes before serving.Learn more about Meat.