Bone marrow: The soft blood-forming tissue that fills the cavities of bones and contains fat and immature and mature blood cells, including white blood cells, red blood cells, and platelets. Diseases or drugs that affect the bone marrow can affect the total counts of these cells.one marrow: The soft blood-forming tissue that fills the cavities of bones and contains fat and immature and mature blood cells, including white blood cells, red blood cells, and platelets. Diseases or drugs that affect the bone marrow can affect the total counts of these cells.
hooks (left) and loops (right). Velcro is a brandname and trademark owned by the Velcro Companies for hook-and-loop fasteners. Hook-and-loop fasteners have a hook side, which is a piece of fabric covered with tiny hooks, and a loop side, which is covered with even smaller and hairier loops.
Velcade (bortezomib) is an antineoplastic agent available for intravenous injection. The proteasome is an enzyme complex that exists in all cells and plays an important role in degrading proteins that control the cell cycle and cellular processes.ortezomib causes a delay in tumor growth in vivo in nonclinical tumor models, including multiple myeloma. The compound bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells. The 26S proteasome is a large protein complex that degrades ubiquitinated proteins.