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Side Effects of L-arginine Hydrochloride For most people, taking L-arginine hydrochloride is thought to be relatively safe. Possible side effects of using L-arginine HCL capsules or powder include bloating, diarrhea, abdominal pain, gout, abnormalities in blood circulation, low blood pressure, inflammation of the lungs and airways, allergies and worsening of asthma symptoms. High-doses of L-arginine may be potentially fatal in children.
Higher doses obviously come with more risk for side effects, plus some research shows that more is not always better when it comes to L-arginineâs functions within blood vessel walls. Interactions and Side Effects: Although L-arginine is generally safe considering itâs a natural amino acid, there are some potential side effects to keep in mind. If you have a history of heart disease, low blood pressure, diabetes, kidney problems or an active virus (like herpes or shingles), itâs not recommended to supplement with L-arginine until you speak with a doctor first.