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Side Effects of L-arginine Hydrochloride For most people, taking L-arginine hydrochloride is thought to be relatively safe. Possible side effects of using L-arginine HCL capsules or powder include bloating, diarrhea, abdominal pain, gout, abnormalities in blood circulation, low blood pressure, inflammation of the lungs and airways, allergies and worsening of asthma symptoms. High-doses of L-arginine may be potentially fatal in children.
Other Side Effects. L-arginine supplementation can lead to several potentially serious side effects in addition to an allergic reaction. In some users, arginine supplementation may cause stomach discomfort, including nausea, stomach cramps, or increased bowel movements. Arginine may also worsen the symptoms of asthma and lower blood pressure.