Disclaimers: This article explains what an FHA underwriter looks for during the loan review process. This is a general overview of events and does not include every possible underwriting scenario. Every mortgage situation is different because every borrower is different.
DIRECT GENETIC TESTING. Huntingtonâs disease has become a model for genetic testing in other adult-onset inherited disorders because the illness is relatively common, and there is widespread experience with it. Genetic testing programs began in 1986 with linkage testing and evolved to direct gene testing shortly after the gene was cloned in 1993.
Huntington disease is a disorder in which nerve cells in certain parts of the brain waste away, or degenerate. The disease is passed down through families. Huntington disease is caused by a genetic defect on chromosome 4. The defect causes a part of DNA to occur many more times than it is supposed to. This defect is called a CAG repeat. Normally, this section of DNA is repeated 10 to 28 times. But in persons with Huntington disease, it is repeated 36 to 120 times.