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Metaphase is when the chromosomes attach to the spindle fibers by their centromeres. This can be confused with the phases:prophase where the spindle fibers form a bridge between the ends of the cell, and anaphase where the spindle fibers draw the chromosomes to the opposite ends of the cell(the cell splits up) Report.
A bit more about each of the 4 main stages of the cell cycle. Mitosis can be further divided into. Prophase - Chromosomes become visible, spindle fibers form, nuclear envelope dissolves. Metaphase - Chromosomes line up in the middle of the cell. Anaphase - Chromosome pairs seperate to different sides of the cell by the spindle fibers.