The pathogenesis of HIE in the newborn period involves the same key players that are also present in adults, namely energy crisis from hypoxia-ischemia, lactic acidosis, excitotoxicity, and free radicals, but there are some important modifiers, which account for different patterns of pathology in newborn babies.
Chordates (phylum Chordata) are a group of animals that includes all the vertebrates (subphylum Vertebrata), as well as two subphylum of invertebrates, the Urochordata (tunicates) and the Cephalochordata (lancelets).lso, the relationships of some chordate groups are not very well understood. 1  Phylum Chordata. 2  Subphylum Urochordata (Tunicates). 3  Subphylum Cephalochordata (Lancelets). 4  Class Myxini or Hyperotreti (hagfish). 5  Subphylum Vertebrata (Vertebrates-animals with backbones). 6  Class Conodonta (Conodonts).
All chordates have the following features at some point in their life (in the case of humans and many other vertebrates, these features may only be present in the embryo): pharyngeal slits - a series of openings that connect the inside of the throat to the outside of the neck. These are often, but not always, used as gills. dorsal nerve cord - a bundle of nerve fibers which runs down the back. It connects the brain with the lateral muscles and other organs.