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Hypertension has various risk factors. The main and most common is because of the lifestyle. There could be too much fat in the body clogging the blood veins. There could also â¦ be defects in the heart or perhaps as a complication of other disease like Diabetes.
The mechanism of hypertension related to rHuEPO remains uncertain. An increase in systemic vascular resistance occurs in all patients, whether or not BP increases. This is due largely to increased blood viscosity and reversal of hypoxic vasodilatation, but other factors may also contribute. A lack of adequate reduction in cardiac output distinguishes patients in whom BP increases, and this in turn may be due to abnormal cardiovascular autoregulation in these patients.