Changes with Age. In most cases, a person's normal respiratory rate will change with age; younger adults, children, and babies will typically have faster respiratory rates, because as people age, their breathing usually slows down.
Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.
This transformational change in Microsoft from a company that put resources toward mp3 players to a company that focuses on software development and operating systems was a seismic shift in their business modus operandi.