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L-arginine has unpredictable effects on insulin and cholesterol-lowering agents. L-arginine may increase the effects of isosorbide mononitrate and other nitric oxide donors, such as glyceryl trinitrate and sodium nitroprusside. Side Effects. L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently.
Side effects of L-arginine For certain groups of people there may be some risks involved in taking L-arginine as a supplement. L-arginine has some potential side effects to be aware of when taking it as a supplement. Some of the more common and benign side effects include: gout; bloating; abdominal pain; airway inflammation; diarrhea; low blood pressure; blood abnormalities; allergies; worsening of asthma; However, L-arginine may result in some serious complications that must be considered.