A regulatory framework Although common in other process manufacturing industries (e.g., food and chemicals), continuous processing is at a nascent stage in the pharmaceutical industry, where batch manufacturing is the prevailing mode.
When the motor neurons in the brainstem are affected (bulbar ALS), the muscles used in speech and swallowing are impaired. ALS only affects muscles that are moved voluntarily (such as those in the mouth or arm) and does not impact those muscles involved in involuntary movements, such as digestion.
In most cases, doctors do not know what causes ALS, but there can be an inherited form of the disease. The disease usually begins with muscle twitching and muscle weakness and progresses to the point where the individual is unable to move their arms or legs.