SAMe (s-adenosyl-L-methionine). Several studies suggest SAMe can help reduce OA pain. In one study, SAMe relieved pain as well as NSAIDs. In another study of people with knee OA, SAMe worked as well as Celebrex in lessening pain and improving joint function, although it took longer to feel the benefits.
Heartburn is felt when stomach acid flows back up into the esophagus (food pipe or gullet), down which food moves from the mouth to the stomach. At least 15 million Americans experience heartburn - the symptom of acid reflux - every day, according to estimates from the American College of Gastroenterology.
Heartburn is a disease that occurs when gastric contents flow backward from the stomach into the esophagus. It is also termed reflux and gastroesophageal reflux disease (GERD) or pyrosis. Heartburn may or may not be associated with mucosal injury; that disease, termed esophagitis, is addressed in a separate article.