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Prevalance of Scleroderma: Estimates for the number of people in the United States with systemic sclerosis range from 40,000 to 165,000. By contrast, a survey that included all scleroderma-related disorders, including Raynaud's phenomenon, suggested a number between 250,000 and 992,500.bout prevalence and incidence statistics: The term 'prevalence' of Scleroderma usually refers to the estimated population of people who are managing Scleroderma at any given time.
The two main types of scleroderma are: 1  Localized scleroderma, which usually affects only the skin, although it can spread to the muscles, joints and bones. 2  Systemic scleroderma, which is the most serious form of the disease, affects the skin, muscles, joints, blood vessels, lungs, kidneys, heart and other organs. Symptoms include discolored patches on the skin (a condition called morphea); or streaks or bands of thick, hard skin on the arms and legs (called linear scleroderma). 2  When linear scleroderma occurs on the face and forehead, it is called en coup de sabre.