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Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.his role of NK cells is critical to immune success particularly because T cells are unable to recognize pathogens in the absence of surface antigens. Tumor cell detection results in activation of NK cells and consequent cytokine production and release.
NK cells are cytotoxic cells of the innate immune system. NK cells are armed with lytic granules that release proteins such as perforin and granzyme to kill virally infected or tumorigenic target cells. Similar to mast cells and eosinophils, cytokine release in NK cells is mediated independently of lytic granules.ytokines released from innate immune cells play key roles in the regulation of the immune response. These intercellular messengers are the source of soluble regulatory signals that initiate and constrain inflammatory responses to pathogens and injury.