Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body.
A familial generation is a group of living beings constituting a single step in the line of descent from an ancestor. In developed nations the average familial generation length is in the high 20s and has even reached 30 years in some nations.
To summarize: A generation in the bible is primarily the age of a man when his first male child is born; but secondarily, the age of a man at his death. The bible then rounds the exact span of years in a generation to be 40 and 100 years as the primary usage, but on occasion, 70 years. And 70 is the average of 40 and 100, which allow the three timeframes to work in numeric harmony to produce the numeric symmetry found throughout the bible.