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INTRODUCTION. Functional somatic symptoms and syndromes are a major health issue. They are common, costly, persistent and may be disabling. Most of the current literature pertains to specific syndromes defined by medical subspecialties. Indeed, each medical subspecialty seems to have at least one somatic syndrome.he concept of a general functional somatic syndrome does not lead to better treatments. Antidepressant efficacy ranges widely in different functional somatic syndromes, and may be more accurately predicted by the presence of comorbid mood disorders. A recent systematic review showed that â ...
By Mayo Clinic Staff. Somatic symptom disorder involves having a significant focus on physical symptoms â such as pain or fatigue â to the point that it causes major emotional distress and problems functioning. You may or may not have another diagnosed medical condition associated with these symptoms.