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Cramps may occur in a skeletal muscle or smooth muscle. Skeletal muscle cramps may be caused by muscle fatigue or a lack of electrolytes (e.g., low sodium, low potassium, or low magnesium, although the evidence has been mixed). Cramps of smooth muscle may be due to menstruation or gastroenteritis.
Leg cramps usually occur as a symptom or a complication to a range of causes. Following are the various disease conditions that leg cramps / spasms are associated with -. Hormonal causes: Leg cramps are fairly common during pregnancy and menopause, and are hugely due to the great alterations in the hormonal profile.holesterol reducing medications and diuretics which contribute to a loss of water and electrolytes and hormonal changes, result in severe leg cramps. Anti-hypertensive (drugs for high blood pressure), oral contraceptives and Hormone Replacement Therapy also cause leg cramps.