First we must appreciate that genes do not act in isolation. The genome in which a genotype is found can affect the expression of that genotype, and the environment can affect the phenotype.Not all pairs of alleles will have the same phenotype: dominance when AA = Aa in phenotype, A is dominant, a is recessive.irst we must appreciate that genes do not act in isolation. The genome in which a genotype is found can affect the expression of that genotype, and the environment can affect the phenotype.
Mannitol may also be used for purposes not listed in this medication guide. You should not receive mannitol if you have severe kidney disease, lung swelling or congestion, severe dehydration, bleeding in your brain not caused by surgery, or if your kidneys have already shut down and you are unable to urinate.o make sure mannitol is safe for you, tell your doctor if you have: 1  a history of kidney disease; 2  heart disease; or. 3  an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
Patients who are allergic to sulfa and require a diuretic (âwaterâ) pill have several options. In general, the sulfa contained in antibiotic drugs has a slightly different chemical structure than the sulfa compounds found in diuretics. As a result, people who are allergic to sulfa antibiotics may be able to take a sulfa-containing diuretic without experiencing a reaction. For patients who are allergic to sulfa-containing diuretics, doctors sometimes prescribe triamterene, spironolactone, amiloride, or ethacrynic acid.