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A high white blood cell count may be caused by a wide range of conditions, which include normal physiological responses to stress, allergic reactions, infection and serious conditions such as cancer. Treatment usually depends on the cause or disease.
The list of other possible causes for a drop in a personâs white blood cell count is long. Autoimmune disorders, congenital disorders that affect the way bone marrow works, disorders of the spleen, certain infectious diseases, cancer and parasitic diseases, among others, can all lead to low white blood cell counts.