This book is actually three books published as one volume for what may be the first time. This is the story of the Spanish princess Katherine of Aragon and it's beautiful, tragic and stirring. Katherine was the daughter of Queen Isabella of Spain.
As a result, a form of vitamin K deficiency, called hemorrhagic disease of the newborn, may develop. This disease involves spontaneous bleeding beneath the skin or elsewhere in the infant's body, and occurs in about 1% of all infants.
Inherited combined deficiency of the vitamin K-dependent clotting factors (VKCFD) is a very rare inherited bleeding disorder that is caused by a problem with clotting factors II, VII, IX, and X.KCFD can also be acquired later in life as a result of disorders of the bowel, liver disease, dietary vitamin K deficiency, or certain medications such as the blood-thinning drug Coumadin Â® . Acquired VKCFD is more common than the inherited form.