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The initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.he initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.
According to the National Institutes of Health's Medline Plus, one symptom of liver disease is jaundice â yellowish skin and eyes. Other symptoms include abdominal pain and swelling, persistent itchy skin, dark urine, pale stools, bloody or black stools, exhaustion, bruising easily, nausea and loss of appetite.