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Prevalance of Scleroderma: Estimates for the number of people in the United States with systemic sclerosis range from 40,000 to 165,000. By contrast, a survey that included all scleroderma-related disorders, including Raynaud's phenomenon, suggested a number between 250,000 and 992,500.bout prevalence and incidence statistics: The term 'prevalence' of Scleroderma usually refers to the estimated population of people who are managing Scleroderma at any given time.
Overview of Scleroderma. Scleroderma, also called systemic sclerosis (SSc), is a chronic autoimmune disease that can affect a number of body systems (i.e., a multisystemic disorder).he disease is more common in adults between the ages of 30 and 50, and is 3 to 5 times more common in women than men. Scleroderma also may affect children and the elderly. The diffuse (widespread) form of the disease occurs more often in African American women than in Caucasian women.