This was the beginning of modern confirmation that we are not alone in the universe. The story involves the recovery of bodies, secrecy, and death threats. Dozens of witnesses have sworn and testified to what they saw.
Numerous experimental observations suggest that local factors play a major role in the pathophysiology of restenosis. Angioplasty is invariably associated with arterial injury that provides a potent stimulus for both platelet adhesion and platelet aggregation.umerous experimental observations suggest that local factors play a major role in the pathophysiology of restenosis. Angioplasty is invariably associated with arterial injury that provides a potent stimulus for both platelet adhesion and platelet aggregation.
Immaturity of the blood-brain barrier probably plays a role in kernicterus. Infusion of bilirubin in experimental animals, after opening of the barrier by injecting hypertonic solutions, causes bilirubin staining. Bilirubin encephalopathy affects parts of the brain that are also involved in perinatal HIE. According to one school of thought, kernicterus is simply due to leakage of bilirubin in areas where the blood-brain barrier has been damaged by HIE. Babies with bilirubin encephalopathy are lethargic, hypotonic or hypertonic, and have a high pitched cry, opisthotonus, seizures, and may die if bilirubin is not lowered.