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Hand cramps are a result of hand muscles and nerve condition. A  common cause of cramping is dehydration, heat exhaustion, fatigue,  and injury or trauma of nerves. This is â¦also common in people with  diabetes and to any condition that affects the nerves outside the  brain and spinal cord. David BÃ¤ckman.
In some instances, the root cause for the cramping is nothing more than overworked hands that require some rest in order to allow the muscle tension to subside to normal levels. People who engage in repetitive hand work are more likely to experience hand cramps from time to time.