1 Preheat the oven to 300 degrees F (150 degrees C).  Warm the au jus sauce in a saucepan over medium heat. Add the roast beef and let it warm up at the same time. While the meat is soaking, place the rolls on a baking sheet with the cut side down. Brush the tops lightly with water and sprinkle with salt and caraway seeds.
PK/PD models. PK/PD modeling (pharmacokinetic/pharmacodynamic modeling) (alternatively abbreviated as PKPD or PK-PD modeling) is a technique that combines the two classical pharmacologic disciplines of pharmacokinetics and pharmacodynamics.
PK is a comedy of ideas about a stranger in the city, who asks questions that no one has asked before. They are innocent, child-like questions, but they bring about catastrophic answers. People who are set in their ways for generations, are forced to reappraise their world when they see it from PK's innocent eyes.