In the United States, about 600,0001 people have PKD, and cystic disease is the fourth leading cause of kidney failure. Autosomal dominant PKD is the most common inherited form. Symptoms usually develop between the ages of 30 and 40, but they can begin earlier, even in childhood.
In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types.
Differentiation is an operation that allows us to find a function that outputs the rate of change of one variable with respect to another variable.Informally, we may suppose that we're tracking the position of a car on a two-lane road with no passing lanes.hat is, the slope of the tangent to the graph of is. Of course, can, and generally will, depend on, so we should really think of it as a function of. We call this process (of computing) differentiation. Differentiation results in another function whose value for any value is the slope of the original function at.