In addition to the purchase price of a property in France, and the various expenses, commissions, and taxes that that purchase entails, there is a further series of outlays that will arise out of your purchase.
When an enzyme binds its substrate, it forms an enzyme-substrate complex. This complex lowers the activation energy of the reaction and promotes its rapid progression by providing certain ions or chemical groups that actually form covalent bonds with molecules as a necessary step of the reaction process.
Induced-fit model: as the substrate enters the active site, the protein (enzyme) changes shape to better fit the substrate. Enzyme-substrate complex: created when the substrate attaches to the enzymes. active site. see book pg 52 fig 3. Enzyme activity and the environment.