Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body.
A familial generation is a group of living beings constituting a single step in the line of descent from an ancestor. In developed nations the average familial generation length is in the high 20s and has even reached 30 years in some nations.
Generation X's children will be or have been born in the 1990s and the following few decades, including Generation Y and the following generation. Assuming generations have a 22-year average length, this means Generation X's children will be born from 1982 to 2025.