Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body.
A familial generation is a group of living beings constituting a single step in the line of descent from an ancestor. In developed nations the average familial generation length is in the high 20s and has even reached 30 years in some nations.
The number of years in a generation will vary from generation to generation, with my own family, from my grand-children back to my 8Xgrandfather it is between 19 and 22 years per generation...with one exception of 45 years !