Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body.
A familial generation is a group of living beings constituting a single step in the line of descent from an ancestor. In developed nations the average familial generation length is in the high 20s and has even reached 30 years in some nations.
In population biology and demography, the generation time is the average time between two consecutive generations in the lineages of a population. In human populations, the generation time typically ranges from 22 to 32 years.