Rosamaria Corona, MD, DSc. Dermoscopy is a noninvasive, in vivo technique primarily used for the examination of pigmented skin lesions; however, it can also assist observers in assessing many amelanotic lesions. Dermatoscopy, epiluminescence microscopy, incident light microscopy, and skin-surface microscopy are synonyms.
General Discussion. Marfan syndrome is a genetic disorder that affects connective tissue, which is the material between cells of the body that gives the tissues form and strength. Connective tissue is found all over the body and multiple organ systems may be affected in individuals with Marfan syndrome.arfan syndrome is a genetic disorder that affects connective tissue, which is the material between cells of the body that gives the tissues form and strength.
Inheritance: Autosomal dominant. Approximately 75% of Marfan mutations are inherited from an affected parent, 25% are de-novo mutations. Disease Characteristics: Marfan syndrome is a connective tissue disorder with striking pleiotropism and clinical variability. Cardiac features are dilatation of the aortic root, aneurysm of the aorta and aortic dissection. The cardiac symptoms often lead to premature death.