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The channel has a large diameter of 0.8x1.1nm, and is non-selective for small ions. However, it has an upper exclusion size limit corresponding to molecular weights of about 600 Dalton of permeants. Because most metabolites have molecular weights lower than 600 Da and have been shown to pass through porin channels, porins are called general diffusion pores.
The main channel, which is 40 feet (12 m) deep and varies in width from 600 to 1,900 feet (180 to 580 m) (although the river broadens to 2,000 feet (610 m) in some of its lower reaches), enters the Columbia about 101 miles (163 km) from the larger river's mouth on the Pacific Ocean.