John Cairns, writing in Scientific American, commented: “These may seem like relatively minor hazards for a patient who has an advanced and rapidly growing cancer, but they would be serious considerations for a woman who has a small [1 / 3 inch] [1 cm] and apparently localized cancer of the breast.
एस्ट्रोजन के स्तर अण्डाशयों के शल्यक उच्छेदन के द्वारा या फिर दवाइयों के द्वारा कम किए जाते हैं ।