The recipient STZ-treated mice remained euglycemic throughout the observation period and histological anal- ysis of islets 4 months after transplantation showed no apparent aberrations in their insulin expression.
Lentiviral vectors, or other vectors such as recombinant adeno-associatedvirus, thatarecapableofintegratinginto the genome, may be well suited to delivering reporter genes that would allow the long-term imaging of grafts.