Ykt6, the soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor protein (SNARE), increases forward transport by increasing the likelihood of membrane vesicles from the ER tethering to Golgi target membranes [62].
The ubiquitin protease Ubp3, together with its cofactor Bre5, function to deubiquitinate the COPII coat protein Sec23p, and likewise promote vesicle exit from the ER [63].