we have utilized the laci-gfp: laco system to visualize the effects of fm7 on meiotic pairing, synapsis, and double-strand break formation in drosophila oocytes.
The analysis of meiotic pairing and synapsis for three lacO reporter couplets in FM7/X heterozygotes revealed they are paired and synapsed during zygotene/pachytene in 70% -80% of oocytes.