Similar to the comparison of POU2F1 to POU5F1 oligonucleotide binding enrichment observed in the pool, we observed an overrepresentation of TRANSFAC centroids in the regionthatrepresentsPOU2F1-specificsequences (Fig.4B, grayareas).
The strongest associations with POU5F1 and POU2F1 binding are found in the numerous highly similar (i.e., overlapping) POU factor binding motifs in the database.