Oxamate alone also promoted oxidation of cytosolic NAD (P) H in oocytes incubated in complete KSOM/AA, further demonstrating a major role for LDH in supplying cytosolic NADH in the resting oocyte.
Lactate-derived pyruvate seems to be minimally metabolised by the mitochondria, as mitochondrial autofluorescence was never affected by lactate addition, even after a delay.