Along with the decidualization mediated by MPA and/or dibutyryl cAMP, the cell growth was significantly inhibited, observed as a reduction in the number of EdU-labeled S-phase cells (Figure 5, CTRL).
il-1β treatment counteracted cell growth arrest even in the presence of mpa and/or dibutyryl camp (figure 5, il-1β), indicating the inhibition of the decidualization capacity of kc02-44d cells.