In addition, we detected strong synergism and complete neutralization of the primary isolate, HIV89.6, in human peripheral blood mono- nuclear cells (PBMC) with the triple combination F105 , 2F5, and 2G12 (3).
Although IgG1b12 alone did not neutralize SHIV89.6P or SHIV-KB9, a fourth-passage molec- ular clone of SHIV89.6P (18 , 21 , 27), the triple combination 2G12, IgG1b12, and 2F5 showed the strongest synergism.