Indications: end-stage<unk>  failure refractory to standard medical/surgical treatment<unk> ed<unk>  is denervated
Resting rate between 90-100 bpm
Response to exertion/stress is blunted by lack of central mediated tachycardia, though can still respond to circulating catecholamines
Upregulation of catecholamine receptors
Atropine is ineffective (no Vagal nerve tone)
Resting rate between 90-100 bpm
Response to exertion/stress is blunted by lack of central mediated tachycardia, though can still respond to circulating catecholamines
Upregulation of catecholamine receptors
Atropine is ineffective (no Vagal nerve tone)
Balance between immune suppression, rejection and susceptibility to infection
Typical regimen includes: calcineurin inhibitor + antimetabolite + steroid
Calcineurin inhibitor
Cyclosporine
Tacrolimus
Steroids
Prednisone/Prednisolone
+/- Antimetabolite
Azathioprine
Mycophenolate mofetil (MMF)
Calcineurin inhibitor
Cyclosporine
Tacrolimus
Steroids
Prednisone/Prednisolone
+/- Antimetabolite
Azathioprine
Mycophenolate mofetil (MMF)
Cyclosporine
Tacrolimus
Prednisone/Prednisolone
Azathioprine
Mycophenolate mofetil (MMF)
Heart transplant complications
Lung transplant complications
Aortic endograft complications
Left ventricular assist device complications
Kidney transplant complications
Liver transplant complications
Pancreas transplant complications
Implantable Cardioverter-Defibrillator complication