Stop or reduce offending agent
may need to discuss with psychiatrist to prescribe new medication or for recs on taper
Acute dystonia, akasthisia, parkinsonism
diphenhydramine 25-50mg PO or IV
OR benztropine 1-2mg PO or IV/IM
continue PO antihistamines for 2 days after stopping antipsychotic
+/- benzodiazepines
Tardive dyskinesia
may only be partially reversible, so minimize occurrence, stop or reduce offending agent promptly
Do NOT give anticholinergics, will exacerbate symptoms
may need to discuss with psychiatrist to prescribe new medication or for recs on taper
diphenhydramine 25-50mg PO or IV
OR benztropine 1-2mg PO or IV/IM
continue PO antihistamines for 2 days after stopping antipsychotic
+/- benzodiazepines
may only be partially reversible, so minimize occurrence, stop or reduce offending agent promptly
Do NOT give anticholinergics, will exacerbate symptoms
Extrapyramidal reaction
Chorea
Sedation 
Sydenham's chorea
Hallucinations
Neuroleptic malignant syndrome
Altered mental status 
Serotonin syndrome