Tailor antibiotics by regional antibiogram
Coverage primarily for Strep
MRSA coverage only necessary if<unk>  associated with: purulence, penetrating trauma, known MRSA colonization, IV drug use, or SIRS
5 day treatment duration, unless symptoms do not improve within that timeframe
Cephalexin 500mg PO q6hrs OR
Add TMP/SMX DS 1 tab PO BID if MRSA is suspected
Most cases of non-purulent<unk>  are caused by Strep. In these cases, the addition of TMP/SMX has been demonstrated to offer no clinical benefit over cephalexin alone.
Clindamycin 450mg PO TID covers both Strep and Staph
Tetracyclines (like Doxycycline) should be avoided in non-purulent<unk>  due to high rates of Strep resistance
Cephalexin 500mg PO q6hrs OR
Add TMP/SMX DS 1 tab PO BID if MRSA is suspected
Most cases of non-purulent<unk>  are caused by Strep. In these cases, the addition of TMP/SMX has been demonstrated to offer no clinical benefit over cephalexin alone.
Clindamycin 450mg PO TID covers both Strep and Staph
Tetracyclines (like Doxycycline) should be avoided in non-purulent<unk>  due to high rates of Strep resistance
Add TMP/SMX DS 1 tab PO BID if MRSA is suspected
Most cases of non-purulent<unk>  are caused by Strep. In these cases, the addition of TMP/SMX has been demonstrated to offer no clinical benefit over cephalexin alone.
Vancomycin 20mg/kg IV q12hrs OR
Clindamycin 600mg IV q8hrs OR
Linezolid 600mg IV q12hrs OR
Daptomycin 4mg/kg IV once daily
coverage extended for Vibrio vulnificus
Doxycycline 100mg PO/IV q12hrs daily + Cefepime 1g IV q12hrs x 10 days
Ciprofloxacin 400mg IV q12hrs x 10 days
Ciprofloxacin 750mg PO q12hrs x 10 days
coverage extended for Aeromonas sp
Ciprofloxacin 400mg IV q12hrs  x 10 days
Ciprofloxacin 500mg PO q12hrs x 10 days
TMP/SMX 2 DS tablets (5mg/kg) PO q12hrs x 10 days
Ceftriaxone 1g (50mg/kg) IV q24hrs
Facial cellulitis
Infectious
Blepharitis
Cellulitis
Periorbital cellulitis
Impetigo
Orbital cellulitis
Erysipelas