Half-life: 3.5-40.6h; 23.6h (heart transplant patients), 18.8h (kidney transplant patients), 11.7h (liver transplant patients); Info: prolonged half-life in hepatic impairment
Metabolism: liver extensively; CYP450: 3A4 substrate
Excretion:feces 92.4%, urine 2.3% (<1% unchanged)
Tacrolimus
Rituximab
Cyclosporine
Interferon-α
Mycophenolate mofetil
Foscarnet
Azathioprine
Idarucizumab