Surgical decompression
Antibiotics
Vancomycin + metronidazole + (cefotaxime or ceftriaxone or ceftazidime)
Ceftazidime is preferred if pseudomonas is considered likely
Can substitute nafcillin or oxacillin for Vancomycin if not MRSA
Treat for 6-8 weeks
If likely nasopharyngeal source (sinusitis, mastoiditis), may consider regiment covering strep, Haemophilus influenzae, and aerobes
Vancomycin + metronidazole + (cefotaxime or ceftriaxone or ceftazidime)
Ceftazidime is preferred if pseudomonas is considered likely
Can substitute nafcillin or oxacillin for Vancomycin if not MRSA
Treat for 6-8 weeks
If likely nasopharyngeal source (sinusitis, mastoiditis), may consider regiment covering strep, Haemophilus influenzae, and aerobes
Ceftazidime is preferred if pseudomonas is considered likely
Can substitute nafcillin or oxacillin for Vancomycin if not MRSA
Epidural abscess 
Intracranial hemorrhage
Subdural empyema
Intra-axial
Discitis
Hemorrhagic stroke 
Vertebral osteomyelitis
Traumatic intracerebral hemorrhage