Clinical diagnosis, no gold standard
Most frequently cited diagnostic criteria
Need 1 major, 4 minor
Petechial rash
Respiratory symptoms with CXR changes
CNS signs unrelated to another condition
Tachycardia
Pyrexia
Retinal changes <unk>  or petechiae)
Renal abnormalities (oliguria, anuria or lipiduria)
Thrombocytopenia
Acute anemia
Elevated ESR<unk>  globules in sputum
CXR/CT scan chest
Bilateral patchy infiltrates
MRI brain: star-field pattern of diffuse, punctate, hyperintense lesions on DWI
Bronchoalveolar lavage
30% of alveolar cells staining for<unk>  strongly asso w diagnosis
Bilateral patchy infiltrates
30% of alveolar cells staining for<unk>  strongly asso w diagnosis
Fat embolism syndrome
Pulmonary embolism
Immersion pulmonary edema
ARDS
Acute chest syndrome
Pulmonary edema
Aspiration pneumonia and pneumonitis
Diffuse alveolar hemorrhage