According to the PIOPED II study, these are the most common presenting signs
Dyspnea at rest or with exertion (73%)
Pleuritic chest pain (44%)
Cough (37%)
Orthopnea (28%)
Calf or thigh pain and/or swelling (44%)
Wheezing (21%)
Hemoptysis (13%)
Tachypnea (54%)
Calf or thigh swelling, erythema, edema, tenderness, palpable cord (47%)
Tachycardia (24%)
Rales (18%)
Decreased breath sounds (17%)
Accentuated pulmonic component of the second heart sound (15%)
JVD (14%)
Fever (3%)
Pulmonary embolism
Acute coronary syndromes 
Pleural effusion
STEMI
Arterial gas embolism
Non-STEMI
Pleuritis
Unstable angina