Chronic cough productive of thick, often purulent sputum
Dyspnea
Crackles/rhonchi, wheezing
+/- pleuritic chest pain
+/- hemoptysis, due to airway neovascularization, can be massive
If advanced;
Hypoxia, clubbing
Pulmonary hypertension, right-sided heart failure
Acute exacerbation results from new/worsened infection, may have fever and constitutional symptoms
Hypoxia, clubbing
Pulmonary hypertension, right-sided heart failure
Bronchiectasis
Pulmonary
Acute bronchitis
Airway obstruction
Atypical pneumonia
Anaphylaxis
Bronchiolitis 
Angioedema