Both fomepizole and<unk>  have greater affinity for ADH than<unk> . Providing IV alcohol is not commonly used but a possible treatment option
Dosing: 15mg/kg IV over 30min; follow by 10mg/kg q12hr until level <20 or acidosis resolves
Indications:<unk>  level >20mg/dL (=6.24 mmmol/L)
Suspected significant<unk>  ingestion with ETOH level <100mg/dL
Coma or altered mental status in patient with unclear history and osm gap >10
Coma or altered mental status in patient with unclear history and unexplained met acidosis and ETOH level <100<unk>  level >20mg/dL (=6.24 mmmol/L)
Suspected significant<unk>  ingestion with ETOH level <100mg/dL
Coma or altered mental status in patient with unclear history and osm gap >10
Coma or altered mental status in patient with unclear history and unexplained met acidosis and ETOH level <100
Dosing
IV: load 800mg/kg; then give 100mg/kg/hr
Oral: 3-4 1-oz "shots" of 80-proof liquor); then give 1-2 "shots" per hour
BAL of 100-150 completely saturates alcohol dehydrogenase
Disadvantages: makes patients inebriated thus requiring close monitoring for CNS and respiratory depression, individual metabolic variations make dosing complicated, frequent serum level monitoring and dosage adjustments are required, administration of the 10% IV<unk>  solution requires central venous access
IV: load 800mg/kg; then give 100mg/kg/hr
Oral: 3-4 1-oz "shots" of 80-proof liquor); then give 1-2 "shots" per hour
Profound acidemia is corrected with sodium bicarbonate
Bicarbonate 1-2mEq/kg IV bolus to attain pH = 7.45-7.50
Follow by infusion of 150mEq/L in D5 at 1.5-2x maintenance fluid rate
Monitor for worsening hypocalcemia
Indications:
May facilitate breakdown of formic acid into carbon dioxide and water
Methanol toxicity
Absinthe
Isopropyl alcohol toxicity
Barbiturates
Ethanol toxicity
Benzodiazepines
Ethylene glycol toxicity
Flunitrazepam 