Effects will typically be seen within 6 hours of ingestion with the exception of sotalol which can have a delayed and prolonged toxicity
Cardiac
Bradycardia
Most common presenting sign
Hypotension
Ventricular dysrhythmias
CNS
Mental status changes
Delirium, coma
Seizure (esp with propranolol)
Other
Hypoglycemia (interfere with gluconeogenesis and glycogenolysis; uncommon in adults)
Helps to differentiate from Calcium Channel Blocker Toxicity
Bronchospasm (uncommon)
Hypothermia
Brugada pattern of EKG with propanolol overdose
Sotalol has type III anti-arrhythmic that can lead to prolonged QT causing torsade de pointes and possibly ventricular fibrillation
Propranolol has sodium channel blockade activity leading to wide QRS
Bradycardia
Most common presenting sign
Hypotension
Ventricular dysrhythmias
Most common presenting sign
Mental status changes
Delirium, coma
Seizure (esp with propranolol)
Delirium, coma
Hypoglycemia (interfere with gluconeogenesis and glycogenolysis; uncommon in adults)
Helps to differentiate from Calcium Channel Blocker Toxicity
Bronchospasm (uncommon)
Hypothermia
Brugada pattern of EKG with propanolol overdose
Sotalol has type III anti-arrhythmic that can lead to prolonged QT causing torsade de pointes and possibly ventricular fibrillation
Propranolol has sodium channel blockade activity leading to wide QRS
Helps to differentiate from Calcium Channel Blocker Toxicity
Beta-blocker toxicity
Cardiac
Clonidine toxicity
Inferior MI 
Digoxin toxicity
Sick sinus syndrome
Calcium channel blocker toxicity
Neurocardiogenic/reflex-mediated