Organisms involved are polymycrobial but often include Fusobacterium necrophorum, Treponema spp, Selenomonas, and Prevotella
Amoxicillin/Clavulanate 875 mg PO two times daily AND
Metronidazole 500mg PO three times daily x 7 days  OR
Clindamycin 300mg PO three times daily OR
Doxycycline 100 mg PO BID x 10 days
If allergic to penicillin, the use Ciprofloxacin 500mg twice daily AND metronidazole 500mg PO three times daily
Metronidazole 500mg PO three times daily x 7 days  OR
For patient with AIDS or immunocompromised with risk of oral candidal infection then add:
Nystatin oral rinse four times daily x 14 days OR
Fluconazole 200mg PO daily x 14 days
Chlorhexidine 0.01% oral rinse BID
Hydrogen peroxide swishing (innexpensive home remedy)
Ibuprofen 400-600mg 3 times daily for pain
Magic Mouthwash (multiple variations) - 300cc of 1:1:1 viscous lidocaine 2%, Maalox, diphenhydramine 12.5mg/5ml elixir
Magic Mouthwash (multiple variations) - 300cc of 1:1:1 viscous lidocaine 2%, Maalox, diphenhydramine 12.5mg/5ml elixir
ENT or OMFS consult for dental debridement may be required in severe infections
Acute necrotizing ulcerative gingivitis
Dental fracture
Traumatic iritis
Dental subluxation
Herpes gingivostomatitis
Dental avulsion
Aphthous stomatitis
Bleeding dental socket