Main cause of mortality in fire-related death
Associated with closed-space fires, especially when patient has decreased mental status (e.g. substance use, head injury)
Thermal injury:
Due to inhaling superheated gases in an enclosed space
Direct thermal trauma and associated edema usually limited to upper airway, but lower respiratory tract may be injured if steam inhaled
Chemical injury:
Direct toxicity to airways and lung parenchyma from noxious chemicals combusted
Due to inhaling superheated gases in an enclosed space
Direct thermal trauma and associated edema usually limited to upper airway, but lower respiratory tract may be injured if steam inhaled
Direct toxicity to airways and lung parenchyma from noxious chemicals combusted
Smoke inhalation injury
Smoke inhalation injury 
Inhalation injury
Chemical injury
Carbon monoxide toxicity
Acrolein
Thoracic trauma
Hydrochloric acid