Drug ratings in pregnancy: C
Lactation: Probably safe
Renal Dosing
Adult
CrCl 50-90: 15mg/kg x1, then usual dose q12-24h
CrCl 10-50: 15mg/kg x1, then usual dose q24h-96h
CrCl <10: 15mg/kg x1, then usual dose q4-7 days
Hemodialysis: Give supplement only if high-flux dialyzer used
Peritoneal dialysis: No supplement
Pediatric
CrCl 10-50: give q18-48h
CrCl <10: give q48-96h
Hemodialysis: Give supplement only if high-flux dialyzer used
Peritoneal dialysis: No supplement
Hepatic Dosing (Adult & Pediatric)
Not defined
Adult
CrCl 50-90: 15mg/kg x1, then usual dose q12-24h
CrCl 10-50: 15mg/kg x1, then usual dose q24h-96h
CrCl <10: 15mg/kg x1, then usual dose q4-7 days
Hemodialysis: Give supplement only if high-flux dialyzer used
Peritoneal dialysis: No supplement
Pediatric
CrCl 10-50: give q18-48h
CrCl <10: give q48-96h
Hemodialysis: Give supplement only if high-flux dialyzer used
Peritoneal dialysis: No supplement
CrCl 50-90: 15mg/kg x1, then usual dose q12-24h
CrCl 10-50: 15mg/kg x1, then usual dose q24h-96h
CrCl <10: 15mg/kg x1, then usual dose q4-7 days
Hemodialysis: Give supplement only if high-flux dialyzer used
Peritoneal dialysis: No supplement
CrCl 10-50: give q18-48h
CrCl <10: give q48-96h
Hemodialysis: Give supplement only if high-flux dialyzer used
Peritoneal dialysis: No supplement
Not defined
Vancomycin
Meropenem
Ertapenem
Teicoplanin
Aztreonam
Fosfomycin
Linezolid
Ceftazidime