Prolonged QT, torsades, ventricular tachycardia, cardiac arrest
Note: effect on QT interval is dose-dependent
In 2001, FDA gave black box warning for risk of torsades de pointes, however there was little evidence to support this
Large cohort of patients in ED showed safety of its administration
Neuroleptic malignant syndrome
Anaphylaxis
Note: effect on QT interval is dose-dependent
In 2001, FDA gave black box warning for risk of torsades de pointes, however there was little evidence to support this
Large cohort of patients in ED showed safety of its administration
Somnolence, dysphoria, anxiety
Akathisia
Hypotension
Tachycardia
Droperidol
Tianeptine
Dantrolene
Benztropine
Homatropine
Pralidoxime
Cyclobenzaprine
Nadalol