All: Adjust repeat doses based on serum levels
<1.2kg
15mg/kg IV q24h
First Dose: 15mg/kg IV x 1
1.2-2kg
10-15mg/kg IV q12-18h
First Dose: 10-15mg/kg IV x 1
>2.1kg
10-15mg/kg IV q8-12h
First Dose: 10-15mg/kg IV x 1
15mg/kg IV q24h
First Dose: 15mg/kg IV x 1
10-15mg/kg IV q12-18h
First Dose: 10-15mg/kg IV x 1
10-15mg/kg IV q8-12h
First Dose: 10-15mg/kg IV x 1
<1.2kg
15mg/kg IV q24h
First Dose: 15mg/kg IV x 1
1.2-2kg
10-15mg/kg IV q8-12h
First Dose: 10-15mg/kg IV x 1
>2.1kg
15-20mg/kg IV q8
First Dose: 15-20mg/kg IV x 1
15mg/kg IV q24h
First Dose: 15mg/kg IV x 1
10-15mg/kg IV q8-12h
First Dose: 10-15mg/kg IV x 1
15-20mg/kg IV q8
First Dose: 15-20mg/kg IV x 1
10-15mg/kg IV q6-8h
First Dose: 10-15mg/kg IV x 1
Max: 1 gram per dose
1000mg IV q12h
First Dose: 1000mg IV x 1
Alt: 10-15mg/kg IV q12
Info: Repeat dosing may require up to 1200-1500mg IV q12h or 10mg/kg IV q8
40mg/kg/day PO divided q6-8h x 7-10 days
First Dose: 10-13mg/kg x 1
Max 500mg/dose, 2000mg/day
For severe infection or recurrence
May use in combination with metronidazole PO
40mg/kg/day PO divided q6-8h x 7-10 days
First Dose: 10-13mg/kg x 1
Max 500mg/dose, 2000mg/day
40mg/kg/day PO divided q6-8h x 10-14 days
First Dose: 10-13mg/kg x 1
Info: Switch to appropriate oral regiment when possible
Vancomycin
Meropenem
Ertapenem
Teicoplanin
Aztreonam
Fosfomycin
Linezolid
Ceftazidime