CBC
Anemia
Thrombocytopenia
Peripheral smear checking for schistocytes, burr cells, helmet cells, spherocytes and segmented red blood cells
LDH (elevated)
Haptoglobin (decreased)
Reticulocyte count (appropriate)
PT/PTT/INR (normal; differentiates from DIC)
Stool tests
Shiga toxin, E. coli O157:H7 test
Urinalysis
Hematuria, casts
LFTs
Increased bilirubin
Chemistry
Creatinine elevation, uremia, hyperkalemia (renal failure)
Anemia
Thrombocytopenia
Peripheral smear checking for schistocytes, burr cells, helmet cells, spherocytes and segmented red blood cells
Shiga toxin, E. coli O157:H7 test
Hematuria, casts
Increased bilirubin
Creatinine elevation, uremia, hyperkalemia (renal failure)
Hemolytic uremic syndrome
Gastroenteritis
Sickle cell crisis
Appendicitis
Hepatorenal syndrome
Colitis
Uremic bleeding syndrome
Intussusception