FDA-approved only for:
Postpartum bleeding
Periprocedural hemorrhage in hemophiliacs.
More common off-label uses:
Severely bleeding trauma patient, systolic blood pressure of <90 and/or heart rate > 110 beats/min, or with expected requirement for massive transfusion
Epistaxis, especially in anticoagulated patients
Under investigation for use in intracranial hemorrhage and GI bleeding
Tranexamic acid
Unfractionated heparin
Dalteparin
Bivalirudin
Enoxaparin
Fondaparinux
Prothrombin complex concentrates
Ticlopidine