Allergy to class/drug
Bleeding diathesis
Active internal bleeding
Current intracranial hemorrhage, subarachnoid hemorrhage
Intracranial neoplasm, arteriovenous malformation, aneurysm, or other conditions that may increase the risk of intracranial bleeding
Recent (<3 mo) intracranial or intraspinal surgery
Recent (<3 mo) serious head trauma
Recent (<3 mo) stroke (for patients being treated for MI or PE)
Severe uncontrolled hypertension
Alteplase
Tenecteplase
Argatroban
Prasugrel
Reteplase
Rivaroxaban
Ticagrelor
Ticlopidine