Traditional cutoff value = 500
Age-adjusted (for patients 50 years or older) = age x 10<unk>  less than OR equal to age x 10 makes VTE unlikely
Maintains high sensitivity while increasing specificity
YEARS and PEGeD adjust cut off base on clinical probability still being studied.<unk>  less than OR equal to age x 10 makes VTE unlikely
Maintains high sensitivity while increasing specificity
D-dimer
Factors that can cause false-negative D-dimer
Cardiac enzymes
Symptoms of PE > 3 days
Troponin
Small PE
Brain natriuretic peptide
Use of qualitative latex fixation test