Neurotoxin found in several marine animals (pufferfish, certain angelfish, blue-ringed octopus)
Heat-stable toxin not destroyed by washing, freezing or cooking
Blocks neuronal action potential by blocking voltage-gated sodium channels
Consumption of improperly prepared pufferfish responsible for vast majority of human toxicity (e.g. fugu restaurants)
Heat-stable toxin not destroyed by washing, freezing or cooking<unk>  binds to and blocks fast-gated sodium channels, blocking conduction of nerve signals.
Tetrodotoxin
Toxins
Trospium
Ciguatera
Cisatricurium
Scombroid
Strychnine
Tetrodotoxin 