Dexamethasone in adults
Only give 15 min prior to or with first dose of antibiotics
10mg IV q6hr x4d
Overall, steroids only decreased mortality in patients with<unk>  caused by Streptococcus pneumoniae
Steroids did decrease rates of any hearing loss, severe hearing loss, and any neurological sequelae in<unk>  caused by all species
This benefit was present in high-income countries but not in low-income countries
Dexamethasone in children and infants
There has been no mortality benefit found with steroid use in children
Steroids decreased the rate of hearing loss in children with<unk>  caused by Haemophilus influenzae
Hydrocortisone for adrenal failure (Waterhouse–Friderichsen syndrome, bilateral adrenal hemorrhage causing adrenal failure, seen in meningococcemia)
Only give 15 min prior to or with first dose of antibiotics
10mg IV q6hr x4d
This benefit was present in high-income countries but not in low-income countries
There has been no mortality benefit found with steroid use in children
Steroids decreased the rate of hearing loss in children with<unk>  caused by Haemophilus influenzae
Meningitis
Migraine headache
Encephalitis
Tension headache
Meningoencephalitis
Cluster headache
Neoplastic meningitis
Meningitis/encephalitis