Complex partial seizures: 30-60mg/kg/day PO (divided bid-tid)
Start: 10-15mg/kg/day PO divided QD-tid
Increase by 5-10mg/kg/day q7 days
Max: 60mg/kg/day
Decrease start dose and titrate slowly in elderly patients
Adjust dose based on treatment response and serum levels
Divide doses >250mg/day
Do not cut/crush/chew with outpen caps
Taper dose gradually to discontinue
Total daily IV dose should equal total oral daily dose
Administer IV dose as a 60-minute infusion (≤20mg/minute)
Start: 10-15mg/kg/day PO divided QD-tid
Increase by 5-10mg/kg/day q7 days
Max: 60mg/kg/day
Decrease start dose and titrate slowly in elderly patients
Adjust dose based on treatment response and serum levels
Divide doses >250mg/day
Do not cut/crush/chew with outpen caps
Taper dose gradually to discontinue
Total daily IV dose should equal total oral daily dose
Administer IV dose as a 60-minute infusion (≤20mg/minute)
Absence seizures, simple and complex:  30-60mg/kg/day PO (divided bid-tid)
Start: 15mg/kg/day PO divided QD-tid, increase by 5-10mg/kg/day every 7 days
Max: 60mg/kg/day
Start: 15mg/kg/day PO divided QD-tid, increase by 5-10mg/kg/day every 7 days
Max: 60mg/kg/day
Bipolar disorder, acute mania: 250-500mg PO tid
Start: 250mg PO tid, may increase dose rapidly to lowest effective dose
Max: 60mg/kg/day
Decrease start dose and titrate slowly in elderly patients
Start: 250mg PO tid, may increase dose rapidly to lowest effective dose
Max: 60mg/kg/day
Decrease start dose and titrate slowly in elderly patients
Migraine headache prophylaxis: 250-500mg PO bid
Start: 250mg PO bid
Start: 250mg PO bid
Status epilepticus (off-label use): IV loading dose: 20 to 40mg/kg
Administer at rate of 3 to 6mg/kg/min
May give an additional dose of 20mg/kg 10 minutes after the loading infusion
Administer at rate of 3 to 6mg/kg/min
May give an additional dose of 20mg/kg 10 minutes after the loading infusion
Valproic acid
Lamotrigine
Ethosuximide
Phenytoin
Valproate
Topiramate
Levetiracetam
Carbamazepine