Hyperacute liver<unk> : encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<unk>  liver<unk> : interval of 8-28 days from jaundice to encephalopathy; this subset has a high incidence of cerebral edema and a poorer prognosis without liver transplant
Subacute liver<unk> : interval of 5-12 weeks from the onset of jaundice to the onset of encephalopathy; this subset has a lower incidence of cerebral edema, but a poor prognosis
Acetaminophen toxicity (most common cause of<unk>  liver<unk>  in the US)
Viral<unk> is<unk> is A<unk> is B<unk> is C<unk> is D<unk> is E
HSV
Epstein-Barr virus
Varicella zoster virus
Toxoplasmosis<unk>  alcoholic<unk> is
Toxins
Mushroom toxicity
Crotinarius mushrooms
Gyromitra mushrooms
Amanita mushrooms
Ischemic<unk> is<unk> is A<unk> is B<unk> is C<unk> is D<unk> is E
HSV
Epstein-Barr virus
Varicella zoster virus
Mushroom toxicity
Crotinarius mushrooms
Gyromitra mushrooms
Amanita mushrooms
Gyromitra mushrooms
Amanita mushrooms
Liver damage from drugs or toxins may be cytotoxic from the primary drug or its metabolites, or may be caused by veno-occlusive disease or hypersensitivity disease
Common Drugs and Toxins
Acetaminophen
Amiodarone
Amphotericin
Anabolic steroids
Azathioprine
Carbamazepine
Chlorpromazine
Cisplatin
Contraceptives
Cyclophosphamide
Erythromycin
Gold salts
Haloperidol
Isoniazid
Ketoconazole
Lovastatin
Methotrexate
Methoxyflurane
Methyldopa
Phenobarbital
Phenytoin
Quinidine
Salicylates
Tetracycline
Valproic acid
Verapamil
Acetaminophen
Amiodarone
Amphotericin
Anabolic steroids
Azathioprine
Carbamazepine
Chlorpromazine
Cisplatin
Contraceptives
Cyclophosphamide
Erythromycin
Gold salts
Haloperidol
Isoniazid
Ketoconazole
Lovastatin
Methotrexate
Methoxyflurane
Methyldopa
Phenobarbital
Phenytoin
Quinidine
Salicylates
Tetracycline
Valproic acid
Verapamil
Wilson's disease: unexplained elevations in LFTs, neuro-psychiatric symptoms, Kayser-Fleischer rings on eye exam
Autoimmune<unk> is: more common in women, liver disease without explanation, may have family history of other autoimmune disorders
Hemochromatosis: family history of liver disease and cardiac disease
Budd-Chiari: history of hypercoagulable disorder, abdominal pain, and ascites
Acute hepatic failure
Hypoglycemia
Acute hepatitis
Hypoxia
Adrenal crisis
Intracerebral hemorrhage or mass
Acute kidney injury
Meningitis/encephalitis