Removal from source
100% oxygen
Hydroxocobalamin (Cyanokit)
5 g over 15 min to start, followed by a second dose PRN
If given as early as possible, has been shown in animal models to prevent PEA
Cobinamide, a vitamin B12 analog, shows promise as first line for H2S toxicity
Can give nitrite component of cyanide antidote kit (do NOT give the thiosulfate portion):
Theoretically increasing methemoglobin formation in blood will cause conversion of<unk>  to sulfmethemoglonin (less toxic)
Amyl nitrite
Sodium nitrite (3% NaNO2) IV over 2-4 minutes; adult dose 10 mL
Obtain methemoglobin level 30 minutes after dose (desired level < 30%)
Hyperbaric oxygen therapy (though not proven to have any benefit)
5 g over 15 min to start, followed by a second dose PRN
If given as early as possible, has been shown in animal models to prevent PEA
Cobinamide, a vitamin B12 analog, shows promise as first line for H2S toxicity
Theoretically increasing methemoglobin formation in blood will cause conversion of<unk>  to sulfmethemoglonin (less toxic)
Amyl nitrite
Sodium nitrite (3% NaNO2) IV over 2-4 minutes; adult dose 10 mL
Obtain methemoglobin level 30 minutes after dose (desired level < 30%)
Hydrogen sulfide toxicity
Carbon monoxide toxicity
Lewisite toxicity
Chemical weapons
Chlorate toxicity
Cyanide toxicity
Silver toxicity
Hydrocarbon toxicity