Occurs when a sulfer atom binds to porphyrin ring of hemoglobin, resulting in permanent oxidation of iron to the ferric state, incapable of oxygen transport
Most often associated with phenazopyridine, dapsone, metoclopramide, sumatriptan
Also associated with industrial chemicals, including trinitrotoluene, hydroxyl amine sulfate, dimethyl sulfoxide, Hydrogen Sulfide
Sulfhemoglobinemia
Methemoglobinemia
Dyshemoglobinemia
Chlorate toxicity
Cyanide toxicity
Carbon monoxide toxicity
Salicylate toxicity
Oxygen toxicity