Marrow infiltration (tumor or infection)
Viral infections (rubella, HIV)
Marrow suppression (commonly chemotherapy or radiation)
Congenital<unk> 
Fanconi anemia
Alport syndrome
Bernand Soulier
Vitamin B12 and/or folate deficiency
Fanconi anemia
Alport syndrome
Bernand Soulier
Idiopathic<unk>  purpura
Thrombotic<unk>  Purpura (TTP)
Hemolytic Uremic Syndrome (HUS)
Disseminated Intravascular Coagulation (DIC)
Viral infections (HIV, mumps, varicella, EBV)
Drugs (heparin, protamine)
Postransfusion or Posttransplantation
Autoimmune destruction (SLE or Sarcoidosis)
Mechanical destruction
Artificial valves
ECMO
HELLP syndrome
Excessive hemorrhage
Hemodialysis, extracorporeal circulation
Splenic Sequestration
Occurs in Sickle cell disease and Cirrhosis
Artificial valves
ECMO
Occurs in Sickle cell disease and Cirrhosis
sulfa antibiotics, ETOH, ASA, thiazide diuretics/furosemide
Too few<unk> 
Nonfunctional
Aspirin
Von Willebrand disease<unk> 
Aspirin
Von Willebrand disease
Acquired (Drug Related)
Warfarin (Coumadin)
Unfractionated heparin
Low molecular weight heparin (i.e. enoxaparin (Lovenox), dalteparin)
Factor Xa Inhibitors (e.g. rivaroxaban, apixaban, fondaparinux, edoxaban)
Direct thrombin inhibitors (e.g. dabigatran, argatroban, bivalirudin)
Illness induced
Vitamin K deficiency
Disseminated Intravascular Coagulation (DIC)
Liver disease induced coagulopathy
Uremic bleeding syndrome
Genetic
Hemophilia
Factor VIII inhibitor
Lupus anticoagulant
Warfarin (Coumadin)
Unfractionated heparin
Low molecular weight heparin (i.e. enoxaparin (Lovenox), dalteparin)
Factor Xa Inhibitors (e.g. rivaroxaban, apixaban, fondaparinux, edoxaban)
Direct thrombin inhibitors (e.g. dabigatran, argatroban, bivalirudin)
Vitamin K deficiency
Disseminated Intravascular Coagulation (DIC)
Liver disease induced coagulopathy
Uremic bleeding syndrome
Hemophilia
Factor VIII inhibitor
Lupus anticoagulant
Thrombocytopenia
Marrow infiltration 
Thrombocytosis
Viral infections 
Neutropenia
Marrow suppression 
Leukopenia
Congenital thrombocytopenia