Half-life: 1.5-5hours (increased if there is hepatic dysfunction)<unk>  autoinduces its own metabolism so half-life is decreased with subsequent dosing.
Metabolism: Hepatic
Excretion: Bile; Urine <30%
Mechanism of Action: inhibits bacterial RNA synthesis<unk>  autoinduces its own metabolism so half-life is decreased with subsequent dosing.
Rifampin
Pyrazinamide
Ethambutol
Rifamycins
Amikacin
Isoniazid
Telavancin
Fidaxomicin