Half-life: 1.9 hours
Metabolism: liver; CYP450 (2C8, 2C9, 3A4 substrate), UGT (2B7 substrate)
Excretion: urine 65%, bile 35%
Mechanism of Action: exact MOA unknown; inhibits cyclooxyrgenase, reducing prostaglandin and thromboxane synthesis
Diclofenac
Ketoprofen
Celecoxib
Ibuprofen
Colchicine
Naproxen
Meloxicam
Acetaminophen