Half-life: 2-3h
Metabolism: extensively in intestinal wall, moderately in liver
Excretion: Urinary
Mechanism of Action: selective α1 agonist causes vasoconstriction
α1
↑SVR
↓HR (reflex bradycardia)
Phenylephrine
Methylergonovine
Acebutolol
Oxymetazoline
Phentolamine
Tamsulosin
Isoproterenol
Methazolamide