Biologically active metabolite of proBNP (released from ventricles in response to increased volume/pressure)
Utility is controversial and may not affect patient centered outcomes
May be trended to gauge treatment response in acute decompensated CHF
May have false negative with isolated diastolic dysfunction
N-terminal proBNP is a biologically inert metabolite of proBNP
American College of Cardiology, American Heart Association, Heart Failure Society of America guidelines as of May 2017<unk>  should be measured in patients presenting with dyspnea to help diagnose or exclude heart failure<unk>  or nt-pro-BNP should be measured to determine prognosis or disease severity in chronic heart failure
Baseline<unk> , cardiac troponin, or both should be measured upon hospital admission to determine prognosis in patients with acutely decompensated heart failure<unk>  should be measured in patients presenting with dyspnea to help diagnose or exclude heart failure<unk>  or nt-pro-BNP should be measured to determine prognosis or disease severity in chronic heart failure
Baseline<unk> , cardiac troponin, or both should be measured upon hospital admission to determine prognosis in patients with acutely decompensated heart failure
Brain natriuretic peptide
CHF/ACS/Cardiogenic shock
Troponin
Pulmonary embolism
Angiotensin II
Pulmonary hypertension
Cardiac enzymes
Renal failure