Local control measures: direct pressure/surgical intervention
Resuscitate with intravenous fluid and / blood products
Oral charcoal administration if drug taken <2 hours before presentation
Hemodialysis will remove ~60% of drug taken over prior 2-3 hours
Consider Idarucizumab (Praxbind): 5 grams IV
Dabigatran reversal
Rivaroxaban reversal
Warfarin reversal
Anti-platelet agent reversal
Unfractionated heparin reversal
Apixaban
Fondaparinux
Enoxaparin