Often defined as creatinine rise of more than 0.5mg/dL or ≥25% above baseline
Vasoconstriction leading to ischemia in the deeper portion of the outer medulla
Toxic to kidney tubular cells, inducing vacuolization, change in mitochondrial function, and apoptosis
Less likely to occur with low and iso-osmolar contrast agents<unk>  not likely to occur in patients with a Cr<1.5 or a GFR >60ml/min
Administration should follow your local hospital protocols
Less likely to occur in iso-osmolar contrast agents (iodixanol/Visipaque) and contrary to traditional teaching, maybe not even an occurrence in patients with creatinine greater than 2.0mg/dL. 
Renal disease
Recent contrast study within 72 hrs
Hypotension
Dehydration
DM
Multiple myeloma
Age > 70
Hypertension
Hyperuricemia
Diuretics
Contrast-induced nephropathy
Poor renal perfusion
IgA nephropathy
Nephrotoxic medications
Emphysematous pyelonephritis
Contrast induced allergic reaction
Post-streptococcal glomerular nephritis
Ureteral stent complications