Highly aggressive malignant bone or soft tissue tumor arising from cells of the neuroectoderm
One-fourth of patients will have metastasis at the time of presentation
It is assumed that almost all patients have subclinical metastasis
Presence and location of metastasis is the major prognostic factor for survival
Metastasis is most frequently seen in bone (spine most common) and lungs
Around 70 to 80 percent survival in those with non-metastatic disease
More common in males
It is assumed that almost all patients have subclinical metastasis
Ewing sarcoma
Multiple myeloma
Osteosarcoma
Chondrosarcoma
Paget disease
Myositis ossificans
Kaposi's sarcoma
Adamantinoma