Withdrawal symptoms due to reduced GABA and increased NMDA receptors
Benzos useful due to cross tolerance at ethanol GABA receptor and longer half-life
Symptom-triggered therapy
As effective as fixed dose therapy, but with more rapid detox
Don’t use phenytoin or fosphenytoin to treat seizures caused by drug toxicity or drug withdrawal.
As effective as fixed dose therapy, but with more rapid detox
Alcohol withdrawal
Ethanol toxicity
Benzodiazepine withdrawal
Alcohol use disorder
Opioid withdrawal
Cocaine withdrawal
Alcohol withdrawal seizures
Barbiturate withdrawal