Half-life: 8h
Metabolism: liver, CYP450: 1A2, 2C9, 2C19 (primary), 3A4 substrate
Excretion: urine 50%, feces 46%
Mechanism of Action: irreversibly binds to P2Y12 adenosine diphosphate receptors, reducing platelet activation and aggregation
Clopidogrel
Ticlopidine
Ticagrelor
Apixaban
Rivaroxaban
Warfarin
Enoxaparin
Eptifibatide