PO
20-30mg/kg/day PO divided q12h
First Dose: 10-15mg/kg PO x 1
Max: 750mg/dose PO
IV
15-30mg/kg/day IV divided q8-12h
First Dose: 5-15mg/kg IV x 1
Max: 400mg/dose IV
20-30mg/kg/day PO divided q12h
First Dose: 10-15mg/kg PO x 1
Max: 750mg/dose PO
15-30mg/kg/day IV divided q8-12h
First Dose: 5-15mg/kg IV x 1
Max: 400mg/dose IV
Max (All): 400mg/dose IV or 500mg/dose PO
Inhalational, GI, Oropharyngeal
20-30mg/kg/day IV/PO divided q12h x 60 days
First Dose: 10-15mg/kg IV x 1 (give with 1-2 additional antibiotics)
Cutaneous
20-30mg/kg/day IV/PO divided q12h x 7-10 days
First Dose: 10-15mg/kg IV/PO x 1
Info: Give x 60 days if bioterrorism suspected
Post-Exposure Prophylaxis
20-30mg/kg/day PO divided q12h x 60 days (or exposure excluded)
First Dose: 10-15mg/kg PO x 1
20-30mg/kg/day IV/PO divided q12h x 60 days
First Dose: 10-15mg/kg IV x 1 (give with 1-2 additional antibiotics)
20-30mg/kg/day IV/PO divided q12h x 7-10 days
First Dose: 10-15mg/kg IV/PO x 1
Info: Give x 60 days if bioterrorism suspected
20-30mg/kg/day PO divided q12h x 60 days (or exposure excluded)
First Dose: 10-15mg/kg PO x 1
Not first line given adverse effects
IV
6-10mg/kg IV q8h
First Dose:
Max: 400mg/dose IV
PO
10-20mg/kg PO q12h
First Dose:
Max: 750mg/dose PO
6-10mg/kg IV q8h
First Dose:
Max: 400mg/dose IV
10-20mg/kg PO q12h
First Dose:
Max: 750mg/dose PO
Ciprofloxacin
Gatifloxacin
Meropenem
Ofloxacin
Metronidazole
Fosfomycin
Vancomycin
Ertapenem