<unk>  is an antiarrhythmic agent commonly used to treat supraventricular and ventricular arrhythmias
Iodine-containing compound with large volume of distribution
Tends to accumulate in several organs, including lungs
Can occur with any dose, though incidence has decreased with use of lower doses
Long half life of<unk> --> effects can persist long after discontinuation<unk>  and metabolites damage lungs:
Directly by cytotoxic effect, production of toxic O2 radicals
Indirectly via immunological reaction
Directly by cytotoxic effect, production of toxic O2 radicals
Indirectly via immunological reaction
Amiodarone pulmonary toxicity
Pneumonia
Digoxin toxicity
CHF
Theophylline toxicity
Pulmonary fibrosis
Cocaine-associated chest pain
Interstitial lung disease