Infections
Many patients already on maintenance azithromycin or tobramycin
Antibiotics for acute pneumonia must be broad and include pseudomonal coverage
e.g. Cefepime, Imipenem, OR Piperacillin/Tazobactam + IV fluoroquinolone, +/- vancomycin for MRSA
Other respiratory adjuncts
Albuterol or other short-acting Beta-2 agonist
Dornase alfa (inhaled recombinant deoxyribonuclease I, hydrolizes DNA in sputum to decrease viscosity)
Nebulized hypertonic saline (reduce sputum viscosity)
Inhaled nitric oxide
Chest physical therapy
See treatment for pancreatitis
Rehydrate if volume depleted, replete electrolytes
Note potential for hypoalbuminemia when giving extensively protein-bound drugs
Many patients already on maintenance azithromycin or tobramycin
Antibiotics for acute pneumonia must be broad and include pseudomonal coverage
e.g. Cefepime, Imipenem, OR Piperacillin/Tazobactam + IV fluoroquinolone, +/- vancomycin for MRSA
e.g. Cefepime, Imipenem, OR Piperacillin/Tazobactam + IV fluoroquinolone, +/- vancomycin for MRSA
Albuterol or other short-acting Beta-2 agonist
Dornase alfa (inhaled recombinant deoxyribonuclease I, hydrolizes DNA in sputum to decrease viscosity)
Nebulized hypertonic saline (reduce sputum viscosity)
Inhaled nitric oxide
Chest physical therapy
Cystic fibrosis
Cerebral palsy
Bronchopulmonary dysplasia
Brash syndrome
Tracheomalacia
Scleroderma
Down syndrome
Idiopathic pulmonary fibrosis