A heterogeneous clinical syndrome characterized by a constellation of signs and symptoms associated with impaired occupational or social functioning involving a range of cognitive, behavioral, and emotional dysfunctions
Suicide risk is higher in:
Males < 30 years of age
Earlier in course of<unk> 
Higher IQ, higher achiever as teen or young adult
More insight and higher executive functioning
Presence of depression, hopelessness, anxiety, insomnia, etc
Substance abuse, alcohol
Family history of suicide
Prior attempt
Be wary of diagnostic overshadowing (e.g. erroneously attributing symptoms to psychiatric disorder when etiology is in fact organic)
Patients with<unk>  have significantly higher rates of stroke, CAD, DM, cancer, HIV, HCV
All cause mortality rate is 200-250% higher for patients with<unk>  than general population
Males < 30 years of age
Earlier in course of<unk> 
Higher IQ, higher achiever as teen or young adult
More insight and higher executive functioning
Presence of depression, hopelessness, anxiety, insomnia, etc
Substance abuse, alcohol
Family history of suicide
Prior attempt
Patients with<unk>  have significantly higher rates of stroke, CAD, DM, cancer, HIV, HCV
All cause mortality rate is 200-250% higher for patients with<unk>  than general population
Schizophrenia
Acute psychosis
Schizophreniform disorder
Schizoaffective disorder
Bipolar disorder
Delusional disorder
Schizotypal personality disorder
Schizoid personality disorder