Decontaminate if occupational exposure
Predominantly supportive/symptomatic treatment
Volume resuscitate if AKI, correct electrolyte abnormalities
Respiratory support, bronchodilators if needed for inhalational exposure
Sodium thiosulfate: for cisplatin overdose
Binds free<unk>  to form nontoxic thiosulfate-cisplatin complex, prevents renal tubule damage
Binds to free<unk>  to form a nontoxic thiosulfate-cisplatin complex, limits renal tubular damage
4g/m2 IV bolus over 15m within 1-2h of overose, then 12g/m2 infusion over 6h
Continue maintenance dosing until urinary<unk>  levels < 1mcg/mL
Binds free<unk>  to form nontoxic thiosulfate-cisplatin complex, prevents renal tubule damage
Binds to free<unk>  to form a nontoxic thiosulfate-cisplatin complex, limits renal tubular damage
4g/m2 IV bolus over 15m within 1-2h of overose, then 12g/m2 infusion over 6h
Continue maintenance dosing until urinary<unk>  levels < 1mcg/mL
Platinum toxicity
Aluminum toxicity
Depleted uranium toxicity
Antimony toxicity
Gold toxicity
Arsenic toxicity
Xylazine toxicity
Barium toxicity