Pregnancy Rating: C
Lactation: Probably safe
Renal Dosing
Adult
Severe chronic renal failure: 648mg PO x 1 then 324mg PO q12h
If on HD give after dialysis
Pediatric
Not defined
Hepatic Dosing
Adult and Pediatric
No adjustment for Child-Pugh Class A or B
Avoid in Child-Pugh Class C
Adult
Severe chronic renal failure: 648mg PO x 1 then 324mg PO q12h
If on HD give after dialysis
Pediatric
Not defined
Severe chronic renal failure: 648mg PO x 1 then 324mg PO q12h
If on HD give after dialysis
Not defined
Adult and Pediatric
No adjustment for Child-Pugh Class A or B
Avoid in Child-Pugh Class C
No adjustment for Child-Pugh Class A or B
Avoid in Child-Pugh Class C
Quinine
Pyrimethamine
Chloroquine
Mefloquine
Primaquine
Praziquantel
Albendazole
Mebendazole