ABPA
Eosinophilia
Skin test + for A. Fumigatus
Serum IgE > 1000 IU/dL or > x 2-fold rise from baseline
Aspergillus precipitins +
Aspergillus radioallergosorbent assay test + and sputum culture
CXR: Fleeting pulmonary infiltrates, mucoid impaction, central bronchiectasis
CT chest: Bronchiectasis, lobulated masses that are mucus-filled dilate bronchi
Aspergilloma
Precipitin Ab test +
CXR/CT: Mass in preexisting cavity, often in upper lobe (crescent of air outlining solid mass)
Invasive<unk>  and CNPA
Visualization of fungi (Silver stain)
Positive culture from sputum, needle biopsy, or BAL
Galactomannan level
CXR: Nodules, cavitary lesions, alveolar infiltrates
CT chest: Halo sign, screscent of air surrounding nodules, wedge-shaped or pleural-based infiltrates, cavitation, pulmonary infarction
Eosinophilia
Skin test + for A. Fumigatus
Serum IgE > 1000 IU/dL or > x 2-fold rise from baseline
Aspergillus precipitins +
Aspergillus radioallergosorbent assay test + and sputum culture
CXR: Fleeting pulmonary infiltrates, mucoid impaction, central bronchiectasis
CT chest: Bronchiectasis, lobulated masses that are mucus-filled dilate bronchi
Precipitin Ab test +
CXR/CT: Mass in preexisting cavity, often in upper lobe (crescent of air outlining solid mass)
Visualization of fungi (Silver stain)
Positive culture from sputum, needle biopsy, or BAL
Galactomannan level
CXR: Nodules, cavitary lesions, alveolar infiltrates
CT chest: Halo sign, screscent of air surrounding nodules, wedge-shaped or pleural-based infiltrates, cavitation, pulmonary infarction
Diagnosis: Clinical deterioration; IgE> 1000IU/mL or > 2-4x baseline; + serology; new infiltrate
Treatment: New radiologic finding and symptoms and change in baseline IgE >500 IU/mL
Aspergillosis
Asthma
Histoplasmosis
Bronchiectasis
Tuberculosis
Eosinophilia
Coccidioidomycosis
ARDS