In select patient populations, consider initiating or increasing outpatient therapy for long-term control (Level C)
First line for people without comorbidities
Hydrochlorothiazide 12.5mg, max 25mg
Need labs before starting, does not work in people with CKD
First line for people with DM and/or proteinuria
ACEi/ARB: Lisinopril either Qday or BID
Need Chem 10 before and after starting to check for hyperkalemia and creatinine
Start 10mg lisinopril QD
Anyone with CAD, CHF
Beta-Blocker (do not need labs)
Amlodipine for anyone, except for people with LE edema (do not need labs)
Start amlodipine 5mg QD
Diltiazem for proteinuria in people unable to tolerate ACEi (do not need labs)
Lasix for CHF and/or lower extremity edema secondary to proteinuria
Hydrochlorothiazide 12.5mg, max 25mg
Need labs before starting, does not work in people with CKD
Need labs before starting, does not work in people with CKD
ACEi/ARB: Lisinopril either Qday or BID
Need Chem 10 before and after starting to check for hyperkalemia and creatinine
Start 10mg lisinopril QD
Need Chem 10 before and after starting to check for hyperkalemia and creatinine
Start 10mg lisinopril QD
Beta-Blocker (do not need labs)
Start amlodipine 5mg QD
JNC 8 Recommendations
Asymptomatic hypertension
Hypertensive emergency
Hypertensive urgency
Stroke
Sympathetic crashing acute pulmonary edema
Eclampsia
Ischemic stroke
Hypertension 