In the US, Hemapure requires individual<unk> IRB and institutional FDA approval and is experimental.
May be able to use this on a US<unk> by requesting "Expanded Access/Compassionate Care" protocol from FDA (see:  https://www.fda.gov/NewsEvents/PublicHealthFocus/ExpandedAccessCompassionateUse/)
Hemopure is approved in South Africa and Russia and is a purifiec acellular bovine hemoglobin in lactated ringer's solution
Dosing: 1 unit (225 mL) administered IV over 4 hours if bleeding
If<unk> develops hypertension slow infusion rate
If<unk> develops hypertension slow infusion rate
Severe anemia in Jehovah's Witness patients
Asplenic patient
Multisystem inflammatory syndrome in children
Bacteremia vs contaminated blood cultures
Healthcare occupational exposure to blood or other body fluids
Seizures in patients with HIV-AIDS
The obese patient
Urethritis in men