Miosis
Nausea/vomiting
Respiratory depression
Mental status depression
QT prolongation (methadone)
Seizure (tramadol)
Acute lung injury
Bowel obstruction, rupture (body packers)
Noncardiogenic pulmonary edema (1-2% of heroin overdoses)
Within 2-4 hrs of overdose
Increased RR, cough, pink frothy sputum, CXR with bilateral infiltrates
Resolves in 24-48 hrs with respiratory supportive care
Within 2-4 hrs of overdose
Increased RR, cough, pink frothy sputum, CXR with bilateral infiltrates
Resolves in 24-48 hrs with respiratory supportive care
Opioid toxicity
Clonidine toxicity
Benzodiazepine toxicity
Organophosphate toxicity
Opioid withdrawal
CO poisoning
Marijuana toxicity
Hypoglycemia