Half-life: 4-6 day (parent drug) and 9.3 days (active metabolite)
Metabolism: Liver, CYP2C19 and CYP2D6 (primary)
Excretion: Urine 80% (11.6% unchanged), Feces 15%
Fluoxetine
Duloxetine
Bupropion
Venlafaxine
Methylphenidate
Nortriptyline
Amitriptyline
Naltrexone