Don’t use phenytoin or fosphenytoin to treat<unk>  caused by drug toxicity or drug<unk> .
Diazepam (Valium) 5-10 mg IV (depending on severity)
May repeat q5-10 min for severe<unk>  (may increase dose by 10 mg every 5-10 min until desired effect achieved, max dose of 200 mg)
Half-life 20-100 h (long acting)
Lorazepam (Ativan) 1-4mg IV (depending on severity)
May repeat q15-20 min for severe<unk>  (titrated to effect)
Rarely causes hepatitis, as opposed to diazepam which may cause a cholestatic hepatitis
Half-life 10-20 h (medium acting)
May repeat q5-10 min for severe<unk>  (may increase dose by 10 mg every 5-10 min until desired effect achieved, max dose of 200 mg)
Half-life 20-100 h (long acting)
May repeat q15-20 min for severe<unk>  (titrated to effect)
Rarely causes hepatitis, as opposed to diazepam which may cause a cholestatic hepatitis
Half-life 10-20 h (medium acting)
For use in cases refractory to benzodiazepine treatment
Propofol
If patient does not respond to high doses of benzodiazepines
0.3-1.25 mg/kg up to 4 mg/kg/hr (consider intubation), for up to 48 hours
Barbiturates (Phenobarbital)
Used when refractory to benzodiazepines (consider after patient has received equivalent of 200 mg diazepam)
Phenobarbital 130-260 mg IV q 15-20 minutes
Can also be used as a first line load at 10 mg/kg prior to giving benzodiazepines to decrease benzodiazepine requirements and ICU admissions 
α-2 agonists (Dexmedetomidine)
Decrease severity of symptoms, but only supplemental to GABA-ergic first-lines
Dexmedetomidine drip, start 0.2 mcg/kg/min, likely needing no more than 0.7 mcg/kg/min
Ketamine
May have some use in refractory cases
Blocks the NMDA receptor which is excited an unregulated. 
If patient does not respond to high doses of benzodiazepines
0.3-1.25 mg/kg up to 4 mg/kg/hr (consider intubation), for up to 48 hours
Used when refractory to benzodiazepines (consider after patient has received equivalent of 200 mg diazepam)
Phenobarbital 130-260 mg IV q 15-20 minutes
Can also be used as a first line load at 10 mg/kg prior to giving benzodiazepines to decrease benzodiazepine requirements and ICU admissions 
Phenobarbital 130-260 mg IV q 15-20 minutes
Can also be used as a first line load at 10 mg/kg prior to giving benzodiazepines to decrease benzodiazepine requirements and ICU admissions 
Decrease severity of symptoms, but only supplemental to GABA-ergic first-lines
Dexmedetomidine drip, start 0.2 mcg/kg/min, likely needing no more than 0.7 mcg/kg/min
May have some use in refractory cases
Blocks the NMDA receptor which is excited an unregulated. 
The propylene glycol diluent in lorazepam, phenobarbital, and diazepam, may induce a hyperosmolar anion gap metabolic acidosis if given as a drip in high doses ≥ 48hrs.  Consider alternatives such as propofol or dexmedetomidine if patients need long term sedation for delirium tremens.
Alcohol withdrawal seizures
Ethanol toxicity
Myxedema coma
Alcohol use disorder
Delirium tremens
Alcohol withdrawal
Neuroleptic malignant syndrome
Status epilepticus