Pregnancy: B
Lactation: Safe
Renal
Adult
CrCl 35-54: give q8
CrCl 11-34: give usual dose x1, then decrease dose 50% and give q12h
CrCl <10: give usual dose x1, then decrease dose 50% and give q18-24h
Hemodialysis: give 0.5-1g supplement
Peritoneal dialysis: 500mg q12h
Pediatric
CrCl 40-70: give usual dose x 1, then decrease daily dose 40% and give q12h
CrCl 20-39: give usual dose x 1, then decrease daily dose 75% and give q12h
CrCl 5-19: give usual dose x 1, the decerase daily dose 90% and give q24h
CrCl <5: not defined
Hemodialysis: give supplement
Peritoneal dialysis: no supplement
Hepatic (Adult & Pediatric)
Not defined
Adult
CrCl 35-54: give q8
CrCl 11-34: give usual dose x1, then decrease dose 50% and give q12h
CrCl <10: give usual dose x1, then decrease dose 50% and give q18-24h
Hemodialysis: give 0.5-1g supplement
Peritoneal dialysis: 500mg q12h
Pediatric
CrCl 40-70: give usual dose x 1, then decrease daily dose 40% and give q12h
CrCl 20-39: give usual dose x 1, then decrease daily dose 75% and give q12h
CrCl 5-19: give usual dose x 1, the decerase daily dose 90% and give q24h
CrCl <5: not defined
Hemodialysis: give supplement
Peritoneal dialysis: no supplement
CrCl 35-54: give q8
CrCl 11-34: give usual dose x1, then decrease dose 50% and give q12h
CrCl <10: give usual dose x1, then decrease dose 50% and give q18-24h
Hemodialysis: give 0.5-1g supplement
Peritoneal dialysis: 500mg q12h
CrCl 40-70: give usual dose x 1, then decrease daily dose 40% and give q12h
CrCl 20-39: give usual dose x 1, then decrease daily dose 75% and give q12h
CrCl 5-19: give usual dose x 1, the decerase daily dose 90% and give q24h
CrCl <5: not defined
Hemodialysis: give supplement
Peritoneal dialysis: no supplement
Not defined
Cefazolin
Oxacillin
Piperacillin
Meropenem
Cefotaxime
Cloxacillin
Ampicillin/Sulbactam
Vancomycin