Pregnancy Rating: X
Lactation risk: Avoid Use
Adult:
CrCl >15: No adjustment
CrCl <15: Not defined
Pediatric:
Safety/efficacy not established in pediatric patients
CrCl >15: No adjustment
CrCl <15: Not defined
Safety/efficacy not established in pediatric patients
Adult:
Child-Pugh Class A or B: No adjustment
Child-Pugh Class C: Not definied
Pediatric:
Safety/efficacy not established in pediatric patients
Child-Pugh Class A or B: No adjustment
Child-Pugh Class C: Not definied
Safety/efficacy not established in pediatric patients
Riociguat
Bosentan
Metaproterenol
Nitroglycerin
Sildenafil
Sotalol
Lofexidine
Ibutilide