Half-life: 12h
Metabolism: Liver extensively; CYP450: 1A1 (primary), 2C8, 2J2, 3A4/5 substrate
Excretion: Urine 40% (6% unchanged); Feces 53% (15% unchanged)
Riociguat
Bosentan
Metaproterenol
Nitroglycerin
Sildenafil
Sotalol
Lofexidine
Ibutilide