Fever
Present in 80% of cases
Heart murmur
Preexisting murmur found in 85% of cases; new murmur found in 48%
CHF
Acute or progressive (70%)
Derm
Osler nodes
Tender red/purple nodules on distal finger and toes
Splinter hemorrhages
Nail bed hemorrhages not extending the length of the nail
Janeway lesions
Non-tender, small erythematous or hemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter
CNS
65% of emboli involve the CNS
Central retinal artery occlusion
Pulmonary
Pneumonia
Empyema
Pulmonary emboli
Cardiac
MI
Myocarditis
Abdominal
Bowel, renal, splenic infarcts
Ophtho
Roth spots
White centered retinal hemorrhage
Associated with multiple systemic illnesses, most commonly bacterial<unk> 
Present in 80% of cases
Preexisting murmur found in 85% of cases; new murmur found in 48%
Acute or progressive (70%)
Osler nodes
Tender red/purple nodules on distal finger and toes
Splinter hemorrhages
Nail bed hemorrhages not extending the length of the nail
Janeway lesions
Non-tender, small erythematous or hemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter
Tender red/purple nodules on distal finger and toes
Nail bed hemorrhages not extending the length of the nail
Non-tender, small erythematous or hemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter
65% of emboli involve the CNS
Central retinal artery occlusion
Pneumonia
Empyema
Pulmonary emboli
MI
Myocarditis
Bowel, renal, splenic infarcts
Roth spots
White centered retinal hemorrhage
Associated with multiple systemic illnesses, most commonly bacterial<unk> 
White centered retinal hemorrhage
Associated with multiple systemic illnesses, most commonly bacterial<unk>
Endocarditis
Critical
Myocarditis
Sepsis
Myocarditis 
PNA with respiratory failure
Constrictive pericarditis
Peritonitis