ABG
HCO3 increases 1 mEq/L for each 10mmHg increase in PaCO2 (acute)
HCO3 increases 3.5 mEq/L for each 10mmHg increase in PaCO2 (chronic)
HCO3 increases 1 mEq/L for each 10mmHg increase in PaCO2 (acute)
HCO3 increases 3.5 mEq/L for each 10mmHg increase in PaCO2 (chronic)
Hypercapnia
Depressed central respiratory drive
Metabolic alkalosis
Structural CNS disease: brainstem lesions
Hypoxemia
Drug depression of respiratory center: opioids, sedatives, anesthetics
Metabolic acidosis
Endogenous toxins: tetanus