Dipeptidyl Peptidase-4<unk>  (gliptans) are a class of oral hypoglycemics that block<unk> -4. This leads to an increase in the activity of incretins, which inhibit glucagon release, which in turn increase insulin secretion and slow gastric emptying, ultimately decreasing blood glucose levels. These drugs are commonly used in the treatment of type 2 diabetes.
Generally used as second or third line treatment for type 2 diabetes mellitus. They may be used as monotherapy or combined therapy.
DPP-4 inhibitors
GLP-1 agonists
Proton-pump inhibitor
ACE inhibitor
SGLT-2 Inhibitor
Angiotensin II receptor antagonists
Calcium channel blockers
Aminoglycosides