Because of differing factor half-lives, can cause transient (24-36 hour) prothrombosis at start of therapy
Bridge with heparin for 1-2 days until INR is in desired range
Bridge with heparin for 1-2 days until INR is in desired range
Warfarin
Clopidogrel
Ticlopidine
Apixaban
Enoxaparin
Ticagrelor
Rivaroxaban
Eptifibatide