GI predominant symptoms:
Activated charcoal 0.5-1gm/kg
Do not give antidiarrheal meds
CNS predominant symptoms:
Place in dark, quiet room
Benzos may be given to patients who are agitated
Consider pyridoxine for refractory seizures, especially if suspecting gyromitra
Muscarinic predominant symptoms:
Consider atropine for severe symptoms; 0.5-1mg IV for adults; 0.01mg/kg IV for peds
Activated charcoal 0.5-1gm/kg
Do not give antidiarrheal meds
Place in dark, quiet room
Benzos may be given to patients who are agitated
Consider pyridoxine for refractory seizures, especially if suspecting gyromitra
Consider atropine for severe symptoms; 0.5-1mg IV for adults; 0.01mg/kg IV for peds
Consider Amatoxin-specific treatments:
Activated charcoal
N-Acetylcysteine (NAC): 150 mg/kg over one hour, 50 mg/kg over 4 hours, 100 mg/kg over 16 hours
Call poison control, consider:
Penicillin G
Silibinin dihemisuccinate
Cimetidine
Vitamin C
Penicillin G
Silibinin dihemisuccinate
Cimetidine
Vitamin C
Mushroom toxicity
Carbamate toxicity
Kratom toxicity
Mushroom toxicity, especially:
Hydrazine toxicity
Amanita muscaria
Chloroform toxicity
Inocybe