The PE derivation and validation study for usage of the<unk>  formula concluded that when combining the d-dimer adjustment with clinical probability, less patients required CTA for exclusion and offered no clinical increase in the rate of missed Pulmonary embolism
Similarly, using the<unk>  in combination with clinical probability can reduce the need for further testing in DVT evaluations with no substantial risk to patient safety
Age adjusted D-dimer
Modified Wells Score
Thromboelastography 
Bubble study
Cardiac enzymes
Brain natriuretic peptide
Aortic ultrasound
Ankle-brachial index