Use for temporary BP or CO boost
Post-intubation hypotension
Propofol-induced hypotension
A-fib with hypotension
Easier to convert well-perfused heart
Retrospective review of push-dose phenylephrine showed improved early hemodynamic stability but increased ICU mortality
Post-intubation hypotension
Propofol-induced hypotension
A-fib with hypotension
Easier to convert well-perfused heart
Easier to convert well-perfused heart
α1, α2, β1, β2 effects
Inopressor
Increases heart rate and inotropy and vasoconstricts
10 cc syringe with 9 cc of NS and draw up 1 mL of 1:10,000 epi (cardiac epinephrine with 10mL of 100 mcg/mL which is 1 mg of epinephrine)
Now have 10mL of 10mcg/mL (1:100,000)
Use 0.5-2mL (5-20 mcg) every 1-5min (similar to epinephrine drip)
Can give peripherally since similar concentrations are give subcutaneously with lidocaine with epinephrine (1:100,000)
Onset - 1min
Duration - 10min
Effects are usually gone within 5 minutes
Now have 10mL of 10mcg/mL (1:100,000)
Use 0.5-2mL (5-20 mcg) every 1-5min (similar to epinephrine drip)
Can give peripherally since similar concentrations are give subcutaneously with lidocaine with epinephrine (1:100,000)
Use 0.5-2mL (5-20 mcg) every 1-5min (similar to epinephrine drip)
Can give peripherally since similar concentrations are give subcutaneously with lidocaine with epinephrine (1:100,000)
Pure α (no effect on heart) potent vasoconstrictor
Useful in tachycardic patient since no effect on HR and might even decrease from reflex parasympathetic response
Increase in heart perfusion can improve cardiac output
Place 1mL of 10mg/mL vial in 100mL NS
Now have 100mcg/mL with total bag containing 10 mg of phenylephrine
Draw up 10mL from bag with syringe
Use 0.5-2mL (50-200mcg) every 1-5 minutes
Can give peripherally since drug is approved for IM or SQ use
Onset - 1min
Duration - 20min
Effects are usually gone within 5 minutes
Now have 100mcg/mL with total bag containing 10 mg of phenylephrine
Draw up 10mL from bag with syringe
Use 0.5-2mL (50-200mcg) every 1-5 minutes
Can give peripherally since drug is approved for IM or SQ use
Can give peripherally since drug is approved for IM or SQ use
Vasopressors
Thrombolytics
Antiarrhythmics
Pericardiocentesis
Stress dose steroids
Extubation
Defibrillation
Vagal maneuvers