Mirrors the treatment for thyroid storm with the exception of antithyroid drugs which offer little potential benefit with the exception of propranolol
Best treated with benzodiazepines
Propranolol 1 to 2 mg IV every 10 to 15 minutes are recommended
Aspirin, should be avoided because it carries a theoretical risk of thyrotoxicity by displacing T3 and T4 from thyroxine-binding globulin.
External cooling is the best means to treat severe hyperthermia in addition consideration of intubation with sedation and continued paralysis.
Plasma exchange or plasmapheresis can be used in the most severe of poisonings<re>Van Huekelom S, et al Plasmapheresis in L-thyroxine intoxication. Vet Hum Toxicol.1979;s21:7</ref>
Levothyroxine toxicity
Sympathomimetic ingestion
Congenital adrenal hyperplasia
Atherosclerosis
Gamma hydroxybutyrate withdrawal
Aortic regurgitation
Hypothyroidism
Thyrotoxicosis