Depends on agent
See antidotes
"Coma cocktail" when suspecting toxic ingestion (mnemonic = "DONT")
Dextrose (50mg IV)
Oxygen
Naloxone (0.2-0.4mg IV/IM, repeat dose 1-2mg)
Empiric opioid ingestion treatment
Thiamine (50-100mg)
Treat or avoid Wernicke encephalopathy
Though some suggest giving thiamine prior to dextrose, do NOT let this delay treatment of hypoglycemia!
Case reports of dextrose precipitating Wernicke's involved thiamine-deficient patients receiving prolonged course of IV glucose, NOT with single bolus
Empiric opioid ingestion treatment
Treat or avoid Wernicke encephalopathy
Though some suggest giving thiamine prior to dextrose, do NOT let this delay treatment of hypoglycemia!
Case reports of dextrose precipitating Wernicke's involved thiamine-deficient patients receiving prolonged course of IV glucose, NOT with single bolus
Toxicology 
Altered Metabolism
Dermatologic nomenclature
Aspirin 
Aria Health 
Withdrawal states 
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Thyroid hormones