Induction = 0.5-1 mg/kg IV over 10s, followed by 0.5 mg/kg every 2-3 minutes as needed
Small incremental doses (10-30 mg) can slowly be administered to effect conscious sedation
Maintenance dose for sedation between 0.1-0.2 mg/kg/min or 25-50 mg IV PRN in healthy patients < 55 years of age
Antiemetic dosing, 10-20 mg IV or 10 μg/kg/min infusion
Fentanyl or morphine<unk>  does not<unk> vide analgesia)
NS for transient hypotension
Lidocaine flush (to reduce injection pain)
5-50 mcg/kg/min IV, increase 5 mcg/kg/min q10min
Avoid<unk> longed use, especially of high doses, to avoid<unk>  infusion syndrome (PRIS)
PRIS usually associated with >65 mcg/kg/min for >24hrs, and critically ill patients with increased endogenous glucocorticoids and catecholamines
PRIS: Heart failure, Rhabdomyolysis, metabolic acidosis, renal failure<unk>  drip of these high dosages can be seen in post-intubation status epilepticus (drip 2-10mg/kg/hr)
PRIS: Heart failure, Rhabdomyolysis, metabolic acidosis, renal failure
Propofol
Ketofol
Etomidate
Ketamine
Fentanyl
Thiopental
Remi-fentanil
Midazolam