Serious toxicity
Conduction delays, SVT, V-tach, hypotension
Respiratory depression
Seizures
Pulmonary Edema
ECG
Sinus Tachycardia (most frequent dysrhythmia)
PR, QRS, QT Prolongation
Abnormal QRS morphology (deep slurred S wave in I and AVL)
Threshold of QRS>100 for seizures
Threshold of QRS>160 for ventricular dysrhythmias
RBBB
Right axis deviation (of terminal 40ms)
Terminal R wave in aVR, S wave in I/aVL
R/S > 0.7
Otherwise, more simply put, tall R wave in aVR
Brugada pattern (15%)
Conduction delays, SVT, V-tach, hypotension
Respiratory depression
Seizures
Pulmonary Edema
Sinus Tachycardia (most frequent dysrhythmia)
PR, QRS, QT Prolongation
Abnormal QRS morphology (deep slurred S wave in I and AVL)
Threshold of QRS>100 for seizures
Threshold of QRS>160 for ventricular dysrhythmias
RBBB
Right axis deviation (of terminal 40ms)
Terminal R wave in aVR, S wave in I/aVL
R/S > 0.7
Otherwise, more simply put, tall R wave in aVR
Brugada pattern (15%)
Abnormal QRS morphology (deep slurred S wave in I and AVL)
Threshold of QRS>100 for seizures
Threshold of QRS>160 for ventricular dysrhythmias
Terminal R wave in aVR, S wave in I/aVL
R/S > 0.7
Otherwise, more simply put, tall R wave in aVR
An urine positive test result suggests only use of a TCA or another drug that cross-reacts with the screen (antimuscarinic, antipsychotic, carbamazepine, etc.)
Quantitative serum level does not correlate with severity of illness
Tricyclic antidepressant toxicity
Medications[1]
Antipsychotic toxicity
Atropine
Clonidine toxicity
Lomotil toxicity
Benzodiazepine toxicity
Antihistamines