Any prior intracranial hemorrhage
Known structural intracranial cerebrovascular disease (e.g. AVM)
Known malignant intracranial neoplasm
Ischemic stroke within last 3 months
Suspected aortic dissection
Active bleeding or bleeding diathesis
Recent surgery encroaching on the spinal canal or brain
Recent closed-head or facial trauma with radiographic evidence of bony fracture or brain injury
Age >75 years
Current use of anticoagulation
PE in Pregnancy
Noncompressible vascular punctures
Traumatic or prolonged CPR (>10min)
Recent internal bleeding (within 2 to 4 weeks)
History of chronic, severe, and poorly controlled hypertension
Severe uncontrolled hypertension on presentation (sys BP >180 or dia BP >110)
Dementia
Remote (>3 months) ischemic stroke
Major surgery within 3 weeks
Thrombolytics for pulmonary embolism
Thrombolytics for STEMI
Thrombolytics for acute ischemic stroke
Balloon tamponade for massive GI bleeding
Resuscitative endovascular balloon occlusion of the aorta
Anti-platelet agent reversal
Cardiovascular antibiotics
Formal echocardiography