History of<unk> Weight loss >10kg in 6mo
Age >50 or <18
No improvement despite therapy
Pain for >4-6wks
Night pain
Pain worse at rest
Vertebral tenderness
Multiple nerve roots affected
Persistent fever
History of IVDA
Recent infection
Immunocompromised state
HIV
Systemic corticosteroids
Transplant
DM
HIV
Systemic corticosteroids
Transplant
DM
Incontinence or retention
Saddle anesthesia
Decreased anal sphincter tone
Bilateral lower extremity weakness or numbness
Neurologic deficit
Muscle Weakness
Radiation of pain
Footdrop
Prolonged use of corticosteroids
History of osteoporosis
Age>70
Mild trauma in age >50yr
Significant trauma in any age
Bony tenderness
Risk factors for PVD
Pulsating mass
Pain at rest or at night
Age >60yrs
Back pain 
Lower back pain
Pelvic pain
Hip pain 
Hip pain
Abdominal pain 
Abdominal pain
Chest pain 