Also known as<unk> 
Noncardiogenic<unk>  edema due to increased microvascular pressure in the<unk>  circulation
Hypoxic<unk>  vasoconstriction leads to<unk>  hypertension
Most lethal of the altitude illnesses with mortality approaching 50% if descent is not completed in a timely manner 
Occurs in <1/10,000 skiers in Colorado; 2-3% of Mt. McKinley climbers
Typical patient is strong and fit; may not have symptoms of altered mental status before onset of<unk> 
Most commonly noticed on the second night at a new altitude
Hypoxic<unk>  vasoconstriction leads to<unk>  hypertension
Heavy exertion
Rapid ascent
Cold
Excessive salt ingestion
Use of a sleeping medication
Preexisting<unk>  hypertension
Preexisting respiratory infection (children)
Previous history of<unk> 
Multiple pathways but thought to be due to an exaggerated<unk>  artery pressure elevation in response to hypoxia  and the following hypothesis:
Breakdown of the alveolar/endothelial barrier leading to increased<unk>  vascular endothelial permeability
Normal wedge pressure, which distinguishes this pathophysiology from heart failure 
Increased intra-cranial pressure which can lead to<unk>  edema 
Breakdown of the alveolar/endothelial barrier leading to increased<unk>  vascular endothelial permeability
Normal wedge pressure, which distinguishes this pathophysiology from heart failure 
Increased intra-cranial pressure which can lead to<unk>  edema
High altitude pulmonary edema
Asthma
High altitude cerebral edema
Bronchitis
High altitude peripheral edema
CHF
Acute mountain sickness
COPD