Can transplant single<unk> , bilateral<unk> s, or heart-lungs
Indications: cystic fibrosis, COPD, idiopathic pulmonary fibrosis > alpha-1 antitrypsin deficiency, primary pulmonary hypertension, bronchiectasis, sarcoidosis, COVID-19<unk>  is denervated
regulation of breathing is not lost, as it is through chest wall efferents
cough response lost below anastomosis
should have normal ABG (unless patient reliant on hypoxic respiratory drive), exercise response, and bronchomotor tone
regulation of breathing is not lost, as it is through chest wall efferents
cough response lost below anastomosis
should have normal ABG (unless patient reliant on hypoxic respiratory drive), exercise response, and bronchomotor tone
Balance between immune suppression, rejection and susceptibility to infection
Typical regimen includes: calcineurin inhibitor + antimetabolite + steroid
Calcineurin inhibitor
Cyclosporine
Tacrolimus
Steroids
Prednisone/Prednisolone
+/- Antimetabolite
Azathioprine
Mycophenolate mofetil (MMF)
Calcineurin inhibitor
Cyclosporine
Tacrolimus
Steroids
Prednisone/Prednisolone
+/- Antimetabolite
Azathioprine
Mycophenolate mofetil (MMF)
Cyclosporine
Tacrolimus
Prednisone/Prednisolone
Azathioprine
Mycophenolate mofetil (MMF)
Lung transplant complications
Bronchitis, Pneumonia 
Heart transplant complications
usually bacterial early in course
Kidney transplant complications
MRSA and pseudomonas common
Tracheostomy complications
Fungi, protozoa, CMV more common >6 weeks post-op