Local wound care, analgesia and tetanus prophylaxis are mainstays of treatment
Grade 1:  Cold packs and NSAIDs
Grade 2/3: IV Opioids and Benzodiazepines
Antivenin - indicated for systemic illness only
Dosage: Usual dose is one to two vials diluted in 50 to 100 mL 5% dextrose or 0.9% sodium chloride, then infused over 1 hour
Use is controversial - Morbidity (pain, cramping and autonomic disturbances) are high, but mortality is low. Antivenin is horse serum derived, and can lead to anaphylaxis and serum sickness
Consider for: Pediatric patients, pregnant women (category C), elderly
Grade 1:  Cold packs and NSAIDs
Grade 2/3: IV Opioids and Benzodiazepines
Dosage: Usual dose is one to two vials diluted in 50 to 100 mL 5% dextrose or 0.9% sodium chloride, then infused over 1 hour
Use is controversial - Morbidity (pain, cramping and autonomic disturbances) are high, but mortality is low. Antivenin is horse serum derived, and can lead to anaphylaxis and serum sickness
Consider for: Pediatric patients, pregnant women (category C), elderly
Routine antibiotic use is not indicated
IV calcium gluconate to reduce muscle spasm is an outdated therapy not favored by toxicologists
Black widow spider bite
Hymenoptera stings 
Octopus bite
Mammalian bites
Armed spider bite
Closed fist infection 
Funnel-web spider bite
Dog bite