Pregnancy Rating: American B, Australia A
Lactation: Not expected to cause any adverse effect 
Renal Dosing
Adult: No adjustment provided in manufacturer's labelling but accumulation of metabolites may be increased in renal dysfunction
Pediatric: No adjustment provided in manufacturer's labelling 
Hepatic Dosing
Adult: Reduce maintenance infusion when used IV (0.75 mg/minute). Monitor concentration.
Pediatric: Use with caution. Reduce dose. 
Adult: No adjustment provided in manufacturer's labelling but accumulation of metabolites may be increased in renal dysfunction
Pediatric: No adjustment provided in manufacturer's labelling 
Adult: Reduce maintenance infusion when used IV (0.75 mg/minute). Monitor concentration.
Pediatric: Use with caution. Reduce dose.
Lidocaine
Quinidine
Prilocaine
Flecainide
Procainamide
Lofexidine
Propafenone
Ibutilide