48% infection
15% malignancy
9% hemorrhage
12% glucocorticoid or granulocyte colony stimulating therapy
48% infection (7% C. difficile)
28% tissue ischemia
7% obstetric process (vaginal or cesarean delivery)
5% malignancy
Consecutive patients presenting to the emergency department
Compared to age-matched controls with moderate leukocytosis (12-24k)
Patients with<unk>  were more likely to have an infection, be hospitalized and die.
Leukemoid Reaction
Infection
Chronic myeloid leukemia
Any severe infection
Acute myeloid leukemia
Particularly c. diff, TB, shigella
Acute lymphocytic leukemia
Drugs/tox