Abbreviation:<unk> 
Definition: a highly variable chronic condition that is characterized by periodic episodes of backward flow of the gastric contents into the esophagus due to improper functioning of a sphincter at the lower end of the esophagus
Usually accompanied by "heartburn" symptoms and histopathologic changes in the esophagus
Affects up to 20% of population
Assume chest pain is cardiac origin until proven otherwise
Usually accompanied by "heartburn" symptoms and histopathologic changes in the esophagus
Decreased pressure of lower esophageal sphincter
High-fat food
Nicotine
Ethanol
Caffeine
Medications (mintrates, calcium-channel blockers, anticholinergics, progesterone/estrogen)
Pregnancy
Decreased esophageal motility
Achalasia
Scleroderma
Diabetes
Prolonged gastric emptying
Anticholinergics
Outlet obstruction
Diabetic gastroparesis
High-fat food
High-fat food
Nicotine
Ethanol
Caffeine
Medications (mintrates, calcium-channel blockers, anticholinergics, progesterone/estrogen)
Pregnancy
Achalasia
Scleroderma
Diabetes
Anticholinergics
Outlet obstruction
Diabetic gastroparesis
Gastroesophageal reflux disease
Gastroesophageal reflux disease 
Esophageal candidiasis
Peptic ulcer disease with or without perforation
Achalasia
Gastritis
CMV esophagitis
Pancreatitis