CBC
DIC labs
DIC occurs in up to 40% of patients
FDP, d-dimer, fibrinogen, coags
Tumor Lysis Syndrome labs
TLS occurs in up to 10% of patients
Chemistry
Uric acid
Calcium
Phosphate
DIC occurs in up to 40% of patients
FDP, d-dimer, fibrinogen, coags
TLS occurs in up to 10% of patients
Chemistry
Uric acid
Calcium
Phosphate
High degree of suspicion needed to make the diagnosis
WBC count usually >100K; can have symptoms with WBC as low as 50K
CXR
Interstial or alveolar infiltrates
Interstial or alveolar infiltrates
Leukostasis and hyperleukocytosis
Malignant airway obstruction
Fever and rash
Bone metastases and pathologic fractures
Deterioration after intubation
Malignant spinal cord compression
Dark raised skin lesions
Malignant Pericardial Effusion and Tamponade