Main goal is to find the underlying cause
Point of care glucose
CBC
Chemistry
LFTs
UA
CXR
Utox
ECG
Head CT
CAM score
Blood and urine cultures
Ammonia level
Tylenol/Aspirin level
LP
Serum Osm
Coags
Cortisol
ABG/VBG
CO level
Delirium
Hypoxic encephalopathy
Excited delirium
Acute toxic-metabolic encephalopathy 
Acute psychosis
Hypoglycemia
Depression
Hyperosmolar state 