There are several options for laboratory evaluation,<unk> t in endemic regions diagnosis is often made by clinical diagnosis due to limited resources
Acid fast staining – does not rule out other related infections such as mycobacterium tuberculosis, sensitivity is approximately 40%
Culture – mycobacterium ulcerans grows slowly in laboratory (positive results require 6 weeks or more), sensitivity is approximately 60%
Histology – sensitivity up to 82%
PCR – sensitivity 70-80%
Buruli ulcer
Eumycetoma
Lichen planus
Pyoderma gangrenosum
Lichen sclerosus
Venous stasis ulcer
Condyloma acuminata
Diabetic skin ulceration