Treat fractures
Pain control
Bisphosphonates (e.g. Zoledronate) are treatment of choice for patients with severe symptoms or advanced<unk>
Paget's disease of bone
Bone tumor 
Ewing sarcoma
Multiple myeloma, myelofibrosis
Osteogenesis imperfecta
Fibrous dysplasia
Myositis ossificans
Intramedullary osteosclerosis