3 prior trials published in 2013 (IMS III, Synthesis EXP,<unk>  RESCUE) showed no benefit of mechanical thrombectomy over tPA alone in AIS
Improved functional outcomes at 90 days using MT +/- tPA in select patients with acute ischemic stroke
No difference in mortality
Proved safety with similar rates of symptomatic ICH
Completion of this trial lead to interim analysis of similar trials and consequent closure (ESCAPE, EXTEND-1A, SWIFT PRIME, REVASCAT)
MR CLEAN
PALS 
Ultrasound: Pelvic
Hemocue
NEXUS cervical spine rule
Ultrasound: Tendons
ADDIE system
AVPU scale