<unk>  (asymptomatic)
Hydroxyurea may be all that is required<unk> 
IV hydration
Prevent dehydration which can worsen condition
Chemotherapy
Only treatment proven to improve survival
Hydroxyurea + leukapheresis
Can be use for cytoreduction if chemo will be delayed
Allopurinol may help prevent Tumor lysis syndrome
Consider rasburicase
Broad spectrum antibiotics
The leading cause of death in blast crisis is infection (patients are functionally neutropenic)
Hydroxyurea may be all that is required
IV hydration
Prevent dehydration which can worsen condition
Chemotherapy
Only treatment proven to improve survival
Hydroxyurea + leukapheresis
Can be use for cytoreduction if chemo will be delayed
Prevent dehydration which can worsen condition
Only treatment proven to improve survival
Can be use for cytoreduction if chemo will be delayed
The leading cause of death in blast crisis is infection (patients are functionally neutropenic)
Leukostasis and hyperleukocytosis
Malignant airway obstruction
Fever and rash
Bone metastases and pathologic fractures
Deterioration after intubation
Malignant spinal cord compression
Dark raised skin lesions
Malignant Pericardial Effusion and Tamponade