First, try applying lateral pressure to the skin and see if it sloughs (Nikolsky’s sign)
Then, to further narrow the differential, consider wither or not the patient is febrile or toxic in appearance
Patients with an<unk>  plus fever are also at high risk for having a deadly diagnosis
Patients with an<unk>  plus fever are also at high risk for having a deadly diagnosis
Erythematous rash
Positive Nikolsky’s sign
Vesiculobullous rashes
Febrile
Dark raised skin lesions
Staphylococcal scalded skin syndrome 
Fever and rash
Toxic epidermal necrolysis/SJS 