<unk>  is lab abnormality of WBC >50-100K
Blood viscosity increases<unk>  is symptomatic<unk> ; it is a medical emergency
Most commonly seen with AML or CML in blast crisis
High blast cell count > WBC plugs in microvasculature
Brain and lung are most commonly affected
20-40% of patients with<unk>  die within 1st week of presentation
Most commonly seen with AML or CML in blast crisis
High blast cell count > WBC plugs in microvasculature
Brain and lung are most commonly affected
Brain and lung are most commonly affected
Leukostasis and hyperleukocytosis
Malignant airway obstruction
Fever and rash
Bone metastases and pathologic fractures
Deterioration after intubation
Malignant spinal cord compression
Dark raised skin lesions
Malignant Pericardial Effusion and Tamponade