Half-life: Immediate release 2-4hrs; Avinza 24hrs; Kadian 11-13hrs
Metabolism: Hepatic
Excretion: Urine and feces
Mechanism of Action:
Binds to opioid receptors in CNS
Inhibits ascending pain pathways
Alters perception and response to pain
Produces CNS depression
Binds to opioid receptors in CNS
Inhibits ascending pain pathways
Alters perception and response to pain
Produces CNS depression
Morphine
Codeine
Methadone
Meperidine
Butorphanol
Fentanyl
Benzocaine
Oxycodone