Abbreviation: TCA
Used in depression and neuropathic pain
Serious<unk>  is almost always seen within 6hr of ingestion
Coingestants that impair metabolism through cytochrome P450 often increase severity of<unk> 
Cocaine can produce the same sodium blockade effect and exacerbate as TCA overdose
Cocaine can produce the same sodium blockade effect and exacerbate as TCA overdose
<1mg/kg: Nontoxic
>10mg/kg: Life-threatening
>1gm: Commonly fatal
Tricyclic antidepressant toxicity
Medications[1]
Antipsychotic toxicity
Atropine
Clonidine toxicity
Lomotil toxicity
Benzodiazepine toxicity
Antihistamines