Begins 6-12hr after onset of therapy or may begin before initiation of treatment or up to 48h afterward
Many appear to be improving from their<unk>  before deteriorating from<unk><unk> 
Premonitory symptoms:
Headache
Incontinence
Seizure
Acute mental status changes
Signs of herniation
Many appear to be improving from their<unk>  before deteriorating from<unk><unk> 
Headache
Incontinence
Seizure
Acute mental status changes
Signs of herniation
Cerebral edema in DKA
Physiologic stress response 
Diabetic ketoacidosis 
Diabetes mellitus 
Diabetic ketoacidosis
Nonketotic hyperglycemia
Alcoholic ketoacidosis
Hyperosmolar hyperglycemic state 