PaO2 - wean O2 for a goal PaO2 >60 mmHg
FiO2 - wean to < 50% if possible while maintaining adequate PaO2
PEEP - refer to ARDSnet protocol to avoid barotrauma
Adjusting mechanical ventilation settings
Weaning mechanical ventilation
Initial mechanical ventilation settings 
Initial mechanical ventilation settings
Lung recruitment maneuver
Airway pressure release ventilation
Pulmonary antibiotics
IV fluid resuscitation