Half-life:
2 minutes
Metabolism:
In tissues and hepatically
Excretion:
Urine as metabolites
Mechanism of Action:β1 stimulation with variable BP effects
2 minutes
In tissues and hepatically
Urine as metabolites
β1
β2
↑↑↑SV
↑↑HR → increases oxygen demand of heart → can worsen ischemia
↓SVR (transient, from β2 agonism)
Dobutamine
Isoproterenol
Adenosine
Norepinephrine
Epinephrine
Esmolol
Milrinone
Metaproterenol