Stage I
Rash on palms of hands and feet
Persistent, heavy vomiting
Altered mental status, confusion, generalized lethargy
High fever
Stage II
Stupor
Hyperventilation
Fatty liver (found by biopsy)
Stage III
Possible coma
Possible cerebral edema
Rarely, respiratory arrest
Stage IV
Deepening coma
Dilated pupils with minimal response to light
Minimal hepatic dysfunction
Stage V
Deep coma
Seizures
Multisystem organ failure
Flaccidity
Hyperammonemia (above 300mg/dL of blood)
Death
Rash on palms of hands and feet
Persistent, heavy vomiting
Altered mental status, confusion, generalized lethargy
High fever
Stupor
Hyperventilation
Fatty liver (found by biopsy)
Possible coma
Possible cerebral edema
Rarely, respiratory arrest
Deepening coma
Dilated pupils with minimal response to light
Minimal hepatic dysfunction
Deep coma
Seizures
Multisystem organ failure
Flaccidity
Hyperammonemia (above 300mg/dL of blood)
Reye syndrome
Shaken baby syndrome
Wellens' syndrome
Head trauma
Kounis syndrome
Viral encephalitis
Irukandji syndrome
Meningitis