Pregnancy Rating: C
Lactation risk: Infant risk minimal
CrCl 50-80 mL/min: reduce dose by 1/3
CrCl 30-50 mL/min: reduce dose by 1/2
CrCl <30 mL/min: reduce dose by 2/3
If HD, use intrathecal with caution, likely reduce dose
No adjustment
Baclofen
Topiramate
Lamotrigine
Icatibant
Levetiracetam
Valproic acid
Ethosuximide
Valproate