Half-life: 4-8h, if GFR < 10 then 17-28h
Metabolism: liver minimally
Excretion: urine primarily (70-90% unchanged), bile/feces (4-8%)
Mechanism of Action: inhibits DNA gyrase and topoisomerase IV
Ofloxacin
Gatifloxacin
Ciprofloxacin
Fosfomycin
Meropenem
Gemifloxacin
Linezolid
Moxifloxacin