Presentation often subtle
Neonatal jaundice
High index of suspicion for jaundice that persists beyond 1st week of life or includes conjugated hyperbilirubinemia
Hepatomegaly
Acholic stools
Dark urine
Late findings: failure to thrive, ascites, splenomegaly
High index of suspicion for jaundice that persists beyond 1st week of life or includes conjugated hyperbilirubinemia
Biliary atresia
More common causes are listed first, followed by less common causes
Neonatal jaundice
Breast milk jaundice
Breast feeding jaundice
Due to substances in milk that inhibits glucuronyl transferase. It may start as early as 3rd day and reaches peak by 3rd week of life. It is unlikely to cause kernicterus
Duodenal atresia
Patient does not receive adequate oral intake which then causes reduced bowel movement/bilirubin excretion. Best diagnosed by looking for signs of dehydration and comparing weight to birth weight.