Suppresses liver glucose production
Metformin 500mg PO BID is first-line agent for type II diabetics
Do not prescribe if creatinine > 1.4 (GFR <40), CHF, hepatic insufficiency, ETOH abuse
Should be withheld for 48hr after IV contrast
Lactic acidosis (due to increased lactate production)
Seen almost exclusively in patients with renal failure
Nausea, diarrhea, crampy abdominal pain
Seen almost exclusively in patients with renal failure
Almost never causes hypoglycemia when taken alone, but can exacerbate hypoglycemia when taken in combination with hypoglycemic agents
Toxic dose unknown
Management: Supportive care
Diabetes medications
CHF medications
Diabetes mellitus 
Tono-Pen use
Hypertension 
Drugs of abuse
Intravenous drug use
Metformin