Back pain (90% of patients)
Progressive and worse when supine
Motor weakness (proximal legs)
Sensory changes and bladder or bowel dysfunction (late findings)
Progressive and worse when supine
Malignant spinal cord compression
Malignant airway obstruction
Spinal cord compression 
Bone metastases and pathologic fractures
Epidural compression syndromes
Spinal stenosis
Malignant Pericardial Effusion and Tamponade
Vertebral osteomyelitis