Though feasible in the ED, antibiotic therapy is typically not offered
Beware of other causes of abdominal pain despite positive testing
PPI plus clarithromycin 500mg twice daily, and amoxicillin 1000mg twice daily for 10-14 days
If penicillin allergic: PPI plus clarithromycin 500mg twice daily, metronidazole 500mg twice daily for 10-14 days
Concomitant therapy adds metronidazole 500 mg BID to triple therapy for 10-14 days
May have highest eradication rates as compared to classical triple therapy or concomitant therapy
Bismuth quadruple therapy for 10 days:
Bismuth subsalicylate 300 mg QID
Lansoprazole 30 mg BID
Tetracycline 500 mg QID
Metronidazole 500 mg TID
Bismuth subsalicylate 300 mg QID
Lansoprazole 30 mg BID
Tetracycline 500 mg QID
Metronidazole 500 mg TID
Helicobacter pylori
Gastroesophageal reflux disease 
Giardia lamblia
Peptic ulcer disease with or without perforation
Campylobacter jejuni
Gastritis
Yersinia enterocolitica
Pancreatitis