Can consider discharge 1-2hr after naloxone administration if all are true:
Ambulatory without assistance
O2 sat >92% (room air)
RR >10bpm
HR >50
Normal temp
GCS 15
Ambulatory without assistance
O2 sat >92% (room air)
RR >10bpm
HR >50
Normal temp
GCS 15
Consider discharge after 4-6hr observation
Methadone toxicity: observe for 12-24hr (longer half-life)
Many states (31) offer protection again criminal liability for prescribing and distributing naloxone to laypeople
A new California law requires providers to offer Naloxone autoinjector prescriptions to certain patients at risk for overdose
Example Prescription
Naloxone 4mg/0.1mL prefilled syringe and intranasal atomizer device
Deliver 1 spray to nostril upon signs of<unk>  overdose. May repeat X 1. Call 911.
Naloxone 4mg/0.1mL prefilled syringe and intranasal atomizer device
Deliver 1 spray to nostril upon signs of<unk>  overdose. May repeat X 1. Call 911.
Indications
Discharged from the ED after<unk>  intoxication or poisoning
Receiving high doses of<unk> s or undergoing chronic pain management
Receiving rotating<unk>  medication regimens
Having a legitimate need for analgesia combined with a history of substance abuse
Using extended/long-acting<unk>  preparations
Completing mandatory<unk>  detoxification or abstinence programs
Recent release from incarceration and past abuser of<unk> s
Opioid toxicity
Clonidine toxicity
Benzodiazepine toxicity
Organophosphate toxicity
Opioid withdrawal
CO poisoning
Marijuana toxicity
Hypoglycemia