Rapid reversal of warfarin anticoagulation (in setting of bleeding or need for invasive procedure)
Bleeding and multiple coagulation defects (e.g. DIC with significant PT/PTT elevation)
Correction of coagulation defects for which no specific factor is available
Transfusion of more than one blood volume with evidence of active bleeding + coagulopathy
Fresh frozen plasma
Packed red blood cells
Protamine sulfate
Whole blood
Vitamin K
Desmopressin
Prothrombin complex concentrates
Antivenin