CBC
ECG
CXR
ESR, CRP
REQUIRE: 2 major or 1 major and 2 minor criteria and evidence of previous GAS pharyngitis
Major diagnostic criteria (CASES)
Carditis (new or changing murmur, cardiomegaly, CHF, pericarditis)
Arthritis, migratory polyarthritis (typically affects knees, ankles, elbows, wrists)
Sydenham's Chorea (abrupt, purposeless movements)
Erythema marginatum (non-pruritic, trunk/extremities, with facial sparing)
Subcutaneous nodules (painless, firm, usually over bones/tendons)
Minor diagnostic criteria<unk> 
Arthralgia
History of previous attack of<unk><unk> 
Prolonged PR interval
Elevated ESR, CRP
Evidence of preceding streptococcal infection
Increased ASO or other strep ab
Positive throat culture for Group A strep
Positive rapid GAS
Recent scarlet<unk> 
Carditis (new or changing murmur, cardiomegaly, CHF, pericarditis)
Arthritis, migratory polyarthritis (typically affects knees, ankles, elbows, wrists)
Sydenham's Chorea (abrupt, purposeless movements)
Erythema marginatum (non-pruritic, trunk/extremities, with facial sparing)
Subcutaneous nodules (painless, firm, usually over bones/tendons)<unk> 
Arthralgia
History of previous attack of<unk><unk> 
Prolonged PR interval
Elevated ESR, CRP
Increased ASO or other strep ab
Positive throat culture for Group A strep
Positive rapid GAS
Recent scarlet<unk>
Acute rheumatic fever
Scarlet fever
Kawasaki disease
Kawasaki Disease
Mitral regurgitation
Viral or other forms of cardiomyopathy
Lyme disease
Leukemia