0 to 18 years of age, 1255 children, some randomized twice during study period giving 1361 encounters for the primary analysis
Diagnosis of DKA (glucose >300, pH <7.25, bicarb <15)
Underlying disorders that affect cognition, alcohol/narcotic use, head trauma, DKA having already received substantial treatment, pregnant, or factors that treating physician wanted specific<unk>  and electrolyte replacement. GCS 11 or lower excluded after year 2 of study (thought that<unk>  regiment shouldn’t be determined on randomization)
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis
Austere peritoneal dialysis
High dose insulin therapy
Hemodialysis/Hemoperfusion
Iridodialysis
Transjugular intrahepatic portosystemic shunt
Reduced-osmolarity oral rehydration solution
Theraputic peritoneal lavage