Most commonly caused by tibia fracture (anterior<unk> 
Consider whenever pain or paresthesia occurs in an extremity after:
fracture (most common risk factor) - can occur with open fracture
crush injury
immobilization
snake bites
burns
prolonged tourniquet application
fluid extravasation into a limb
soft tissue infection
extreme exertion
fracture (most common risk factor) - can occur with open fracture
crush injury
immobilization
snake bites
burns
prolonged tourniquet application
fluid extravasation into a limb
soft tissue infection
extreme exertion
Immediate threat is viability of nerve and muscle; later threat is infection, gangrene, rhabdomyolysis, renal failure
Tissue perfusion is difference between diastolic BP and<unk>  pressure
As<unk>  pressure increases, tissue perfusion decreases
As<unk>  pressure increases, tissue perfusion decreases
Orthopedic
Tibial fracture
Forearm fracture
Vascular
Ischemic-reperfusion injury
Hemorrhage
Can be spontaneous in anticoagulated patients
Iatrogenic
Vascular puncture in anticoagulated patients
IV/intra-arterial drug injection
Constrictive casts
Soft tissue injury
Prolonged limb compression
Crush injury
Burn
Snake bite
Expanding hematoma
Tibial fracture
Forearm fracture
Ischemic-reperfusion injury
Hemorrhage
Can be spontaneous in anticoagulated patients
Can be spontaneous in anticoagulated patients
Vascular puncture in anticoagulated patients
IV/intra-arterial drug injection
Constrictive casts
Prolonged limb compression
Crush injury
Burn
Snake bite
Expanding hematoma
Compartment syndrome
Crush syndrome
Contusion
Cytokine release syndrome
NSAID toxicity
Degloving injury
Pancoast syndrome
Morel-Lavallée lesion