Normal lung parenchyma is interspersed with areas of decrease compliance
Unlike ARDS, in which lung injury more uniform
Mechanical ventilation strategies learned from ARDS not completely transferrable
Median survival time 3 yrs after diagnosis
Prevalence about 10-20 cases per 100,000 people
AE-IPF = Acute Exacerbation of<unk> 
Acute exacerbations carry mortality up to 80%
60% die from<unk> , others die from:
VTE
Cardiovascular (ACS, CHF)
Infection
Unlike ARDS, in which lung injury more uniform
Mechanical ventilation strategies learned from ARDS not completely transferrable
VTE
Cardiovascular (ACS, CHF)
Infection
Idiopathic pulmonary fibrosis
Interstitial pneumonias 
Bronchiectasis
Lung malignancy
Sarcoidosis
Aspiration pneumonia or pneumonitis
CMV pneumonia
Bacterial, viral, or fungal pneumonia