Clinical features can range from mild local irritation to organ dysfunction
GI
Anorexia
Nausea/vomiting
Leading to profound volume depletion
Abdominal pain
Diarrhea
Hemorrhagic gastritis
Pancreatitis
Can react with water in salvia, producing sufficient hydrochloric acid to cause GI burns
CV
Decreases myocardial contraction
Decreased systolic pressure through decreased coronary vasomotor tone
Bradycardia
EKG changes
More common in pentavalent preparations
Prolonged QT
Inversion or flattening of T waves
Torsades de pointes
Pulmonary
Local irritation
Laryngitis and Tracheitis<unk>  pneumoconiosis
Chronic exposure
Cough, wheezing, and exertional dyspnea
CXR showing diffuse, dense, punctate non-confluent opacities in the middle and lower lobes
Renal
Proteinuria
Increased BUN
ATN
Renal failure
Hepatic
Elevated aminotransferase
Hepatic necrosis
Hematologic
Thrombocytopenia
Leukopenia
Severe anemia seen in HIV patients being treated for leishmaniasis
Dermatologic<unk>  Spots
Papules and pustules around sweat glands
Can resemble varicella
Eczema
Lichenification
Musculoskeletal
Myalgias
Arthralgias
Reproductive
Increased risk of spontaneous abortion and premature labor
Ocular
Local irritation
Conjunctivitis
Photophobia
Corneal burn
Anorexia
Nausea/vomiting
Leading to profound volume depletion
Abdominal pain
Diarrhea
Hemorrhagic gastritis
Pancreatitis
Can react with water in salvia, producing sufficient hydrochloric acid to cause GI burns
Leading to profound volume depletion
Decreases myocardial contraction
Decreased systolic pressure through decreased coronary vasomotor tone
Bradycardia
EKG changes
More common in pentavalent preparations
Prolonged QT
Inversion or flattening of T waves
Torsades de pointes
More common in pentavalent preparations
Prolonged QT
Inversion or flattening of T waves
Torsades de pointes
Local irritation
Laryngitis and Tracheitis<unk>  pneumoconiosis
Chronic exposure
Cough, wheezing, and exertional dyspnea
CXR showing diffuse, dense, punctate non-confluent opacities in the middle and lower lobes
Laryngitis and Tracheitis
Chronic exposure
Cough, wheezing, and exertional dyspnea
CXR showing diffuse, dense, punctate non-confluent opacities in the middle and lower lobes
Proteinuria
Increased BUN
ATN
Renal failure
Elevated aminotransferase
Hepatic necrosis
Thrombocytopenia
Leukopenia
Severe anemia seen in HIV patients being treated for leishmaniasis<unk>  Spots
Papules and pustules around sweat glands
Can resemble varicella
Eczema
Lichenification
Papules and pustules around sweat glands
Can resemble varicella
Myalgias
Arthralgias
Increased risk of spontaneous abortion and premature labor
Local irritation
Conjunctivitis
Photophobia
Corneal burn
Antimony toxicity
Aluminum toxicity
Thallium toxicity
Organophosphate toxicity
Arsenic toxicity
Xylazine toxicity
Barium toxicity
Chromium toxicity