Predominantly found in the<unk> , bile ducts, kidney, and bones
Because of its abundant production in biliary duct tissue, elevation reflects a problem with biliary stasis or obstruction
Elevation may also occur in patients with increased bone turnover (e.g. 2/2 puberty, osteoporosis, hyperparathyroidism, Paget's disease, etc.)
Elevation may also occur in patients with increased bone turnover (e.g. 2/2 puberty, osteoporosis, hyperparathyroidism, Paget's disease, etc.)
Liver function tests
Cardiac enzymes
HIV testing 
Cardiac ultrasound
ECG 
Urine toxicology screen
Microbiology 
Biliary ultrasound