Acute GI hemorrhage in a patient with cirrhosis is an emergency that requires prompt attention with intravascular volume support and blood transfusions, being careful to maintain a hemoglobin of ~8 g/dL (Class I, Level B).
Short-term antibiotic prophylaxis should be instituted in any patient with cirrhosis and GI hemorrhage (Class I, Level A). Oral norfloxacin (400mg BID) or intravenous ciprofloxacin (in patients in whom oral administration is not possible) is the recommended antibiotic (Class I, Level A). In patients with advanced cirrhosis intravenous ceftriaxone (1 g/day) may be preferable particularly in centers with a high prevalence of quinolone-resistant organisms (Class I, Level B).
Pharmacological therapy (somatostatin or its analogues octreotide and vapreotide; terlipressin) should be initiated as soon as variceal hemorrhage is suspected and continued for 3–5 days after diagnosis is confirmed (Class I, Level A).
EGD, performed within 12 hours, should be used to make the diagnosis and to treat variceal hemorrhagey (Class I, Level A).
Balloon tamponade should be used as a temporizing measure (maximum 24 hours) in patients with uncontrollable<unk>  for whom a more definitive therapy (e.g., TIPS or endoscopic therapy) is planned (Class I, Level B).
Upper GI bleeding guidelines
Hinchey classification for diverticulitis
Glasgow-Blatchford Bleeding Score
ECGs by Diagnosis
PERC rule
GI antibiotics
DVT ultrasound
Prehospital protocol pediatric anaphylaxis