Absolute risk of nosocomial<unk> in conservatively vs liberally transfused patients: 12% vs 17%
Bacterial contamination of products, especially platelets
1 of 2000-3000 platelet transfusions results in bacterial<unk> Gram-positive bacteria (e.g. staph due to contamination with skin puncture during collection
Gram-negative bacteria (e.g. e. coli) due to asymptomatic bacteremia in donor
Anaplasmosis, brucellosis, ehrlichiosis have all been documented
Parasitic<unk>  rare but reported. Those reporting recent travel to malaria-endemic regions are barred from donation
Babesiosis, Chagas, Leishmaniasis, Malaria
Viral<unk> 
Risk of<unk> from single transfusion in the US:
HIV<unk>  1 in 2 million
HBV: 1 in 300,000
HCV: 1 in 1.5 million
West nile virus: 1 in 350,000
Prion disease
1 of 2000-3000 platelet transfusions results in bacterial<unk> Gram-positive bacteria (e.g. staph due to contamination with skin puncture during collection
Gram-negative bacteria (e.g. e. coli) due to asymptomatic bacteremia in donor
Anaplasmosis, brucellosis, ehrlichiosis have all been documented
Babesiosis, Chagas, Leishmaniasis, Malaria
Risk of<unk> from single transfusion in the US:
HIV<unk>  1 in 2 million
HBV: 1 in 300,000
HCV: 1 in 1.5 million
West nile virus: 1 in 350,000
Transfusion infections
Transplant complications
Transfusion-associated circulatory overload
Acute transfusion reaction
Stem cell transplant complications
Allergic transfusion reaction
Tumor lysis syndrome
Hyperviscosity syndrome