Glucose
Chemistry
ECG
Troponin
Total CK
LFT
Coags
Consider CT/LP if concern for ICH
Consider lactate/CTA if concern for bowel ischemia
Generally clinical and historical diagnosis
See Toxidromes
Urine toxicology screen is rarely helpful
Can be potentially positive up to 72hr post-ingestion
Often negative in acute ingestion
ECG
May show QRS, QT prolongation
See Toxidromes
Can be potentially positive up to 72hr post-ingestion
Often negative in acute ingestion
May show QRS, QT prolongation
Unreliable in very acute intoxication
Qualitative urine detection of<unk>  metabolite benzoylecgonine at cut-off of 300 ng/ml
On average, shows up in urine 24-48 hrs after use
Up to 22 days in chronic users
On average, shows up in urine 24-48 hrs after use
Up to 22 days in chronic users
Cocaine toxicity
Cocaine
Carbamate toxicity
Amphetamines
Tianeptine toxicity
Synthetic cathinones 
Phencyclidine toxicity
Ketamine