Advantages of FWB
FWB provides the coagulation factors, buffer capacity, platelets, and oxygen carrying capacity all in one that single component therapy does not.
FWB is more concentrated than component therapy (higher hematocrit)
FWB does not contain the high volume of anticoagulant and additives as compared to component therapy
FWB is more readily available in austere locations as it can often be 'stored' in walking pre-screen donors
FWB has no loss of clotting factor or platelet activity often associated with cold storage of component<unk>  products
FWB has no "storage lesion" which causes decline in platelet function and coagulation factors, chelation of calcium by preservatives, and increased acidity common to<unk>  products which have been fractionated and kept in storage.
Disadvantages of FWB
Must be ABO-type specific as it contains both RBCs and plasma
Increased risk of<unk> -borne diseases
Increased risk of bacterial contamination due to the field conditions
Decreased exercise or operational performance in donors generally considered to be minimal
Increased risk of clerical errors (ABO typing) due to chaotic nature during which FWB may be used
FWB is not FDA-approved
FWB provides the coagulation factors, buffer capacity, platelets, and oxygen carrying capacity all in one that single component therapy does not.
FWB is more concentrated than component therapy (higher hematocrit)
FWB does not contain the high volume of anticoagulant and additives as compared to component therapy
FWB is more readily available in austere locations as it can often be 'stored' in walking pre-screen donors
FWB has no loss of clotting factor or platelet activity often associated with cold storage of component<unk>  products
FWB has no "storage lesion" which causes decline in platelet function and coagulation factors, chelation of calcium by preservatives, and increased acidity common to<unk>  products which have been fractionated and kept in storage.
Must be ABO-type specific as it contains both RBCs and plasma
Increased risk of<unk> -borne diseases
Increased risk of bacterial contamination due to the field conditions
Decreased exercise or operational performance in donors generally considered to be minimal
Increased risk of clerical errors (ABO typing) due to chaotic nature during which FWB may be used
FWB is not FDA-approved
Whole blood
Packed red blood cells
Dextrose
Fresh frozen plasma
Blood products
Methylene blue
Glucagon
N-Acetylcysteine