A host response may result in sepsis
Typically present with fever, chills and hypotension.
The presence of chills is also independently associated with blood stream infections
Alternatively bacteria may spread hematomagously to distant sites in body:
Endocarditis
Meningitis
Osteomyelitis
Bacteremia
Fever and rash
Neutropenic fever
Burns
Anemia
Pancytopenia
Coagulopathy 
Leukopenia