Autonomic dysfunction
Bulbar dysfunction
Initial vital capacity <20 mL/kg
Initial negative inspiratory force <–30 cm of water
Decrease of >30% of vital capacity or negative inspiratory force
Inability to ambulate
Treatment with plasmapheresis
Anticipated clinical course requiring mechanical ventilation
Guillain-Barre syndrome
Neuromuscular weakness
Lambert-Eaton myasthenic syndrome
Upper motor neuron:
Amyotrophic lateral sclerosis
CVA
Polymyositis
Hemorrhagic stroke