Initial dose: 6 vials
Typically diluted into 250 cc or 1 L of normal saline and infused over an hour
Same dose for both adults and pediatrics (may have to adjust the dilution of CroFab for small children so that they are not volume overloaded)
May repeat dose (2 vials) at 6, 12, and 18 hours later if symptoms not controlled
Maintance therapy may be indicated after initial dosing based on local protocols even if control is achieved.
Maintance therapy may be indicated after initial dosing based on local protocols even if control is achieved.
Observe for progression of envenomation during and after antivenom infusion
Measure limb circumference at several sites above and below bite
Mark advancing border of edema q30min
Repeat labs q4hr or after each course of antivenom (whichever is more frequent)
Acute allergic reactions occur in <10% pts
If occurs stop infusion and give epinephrine/antihistamines if needed
Recurrent thrombocytopenia has been described up to 2 weeks after transfusion with<unk> AV and is likely a result of isolated renal clearance of<unk> AV and persistent presence of actual venom in serum.
Warrants close monitoring of platelets by primary physician or return visit after discharge
Serum sickness is unlikely but precautions should be given to patents upon discharge
If occurs stop infusion and give epinephrine/antihistamines if needed
Warrants close monitoring of platelets by primary physician or return visit after discharge
Pregnancy category C
Crotalidae polyvalent immune Fab 
COVID-19 Vaccine 
United States Antibiogram
Traditional chinese medicine toxicology
Atovaquone-proguanil
Pepper spray
Post exposure prophylaxis antibiotics
Loa loa