ANC = (total WBC) x (%segs + %bands)
Nadir usually occurs 5-10d after chemo
Duration of<unk>  depends on type of cancer treatment
Solid tumor treatments: <5d
Hematologic malignancies: 14d or longer
(Leukemia or lymphoma) + chemo most commonly associated with<unk> 
Solid tumor treatments: <5d
Hematologic malignancies: 14d or longer
ANC <500 OR <1000 with predicted nadir of <500 in 48h AND
Fever ≥ 38.3˚C (100.9˚F) once OR sustained temperature ≥38 (100.4) for >1hr
Oral temperature (do not obtain rectal temp; risk of inducing bacteremia)
Oral temperature (do not obtain rectal temp; risk of inducing bacteremia)
Definitive cause only found in 30%
Endogenous flora 80%
E. Coli, Enterobacter, anaerobes
Skin
Staph, strep
Respiratory tract
Step pneumonia, klebsiella, corynebacterium, pseudomonas
Other
C. diff, mycobacterium, candida, Aspergillus
E. Coli, Enterobacter, anaerobes
Staph, strep
Step pneumonia, klebsiella, corynebacterium, pseudomonas
C. diff, mycobacterium, candida, Aspergillus<unk>  Enterocolitis (Typhlitis)
Mucormycosis
Hepatosplenic Candidiasis
Occurs after<unk>  resolves and ANC has come up allowing abscess formation
Treat with amphotericin B
Occurs after<unk>  resolves and ANC has come up allowing abscess formation
Treat with amphotericin B
Neutropenic fever
Transfusion reaction
Acute fever
Medication allergies and toxicities
Fever and rash
Tumor-related fever
Erythematous rash
Malignant airway obstruction