Spreads from source lymph node to adjacent nodes
About half of cases related to Epstein-Barr virus
HIV is also a risk factor
More common in males
Bimodal distribution: young adulthood and older aged
Most common malignancy in ages 15-19 years
Survival >90% in low-risk patients
HIV is also a risk factor
Hodgkin's lymphoma
Kaposi's sarcoma
Non-Hodgkin's lymphoma
Chronic lymphocytic leukemia
Mononucleosis
Tuberculous lymphadenitis
Toxoplasmosis
Multiple myeloma