Used in  β-blocker and calcium channel blocker toxicity
Response is delayed for 30 to 60 minutes
Recommend simultaneous implementation of other<unk> es to support the patient's pulse and blood pressure
High dose insulin therapy
Opioid free regimens
Metformin
GLP-1 agonists
Glyburide
DPP-4 inhibitors
Pioglitazone
Urinary alkalinization