ABC’s and Resuscitation if necessary
Management guided by association with Epiglottitis or Streptococcal Pharyngitis
General Treatment
Airway protection with fiberoptic intubation or tracheostomy
Dexamethasone 0.15mg/kg
Nebulized epinephrine
Antibiotic treatment
Pediatric:
(Cefotaxime 50mg/kg IV q8h and Ceftriaxone 50mg/kg IV q24hr) plus Vancomycin 15mg/kg IV q12h
Adult:
(Cefotaxime 2gm IV q4-8h or Ceftriaxone 2gm IV q24h) plus Vancomycin
Airway protection with fiberoptic intubation or tracheostomy
Dexamethasone 0.15mg/kg
Nebulized epinephrine
Pediatric:
(Cefotaxime 50mg/kg IV q8h and Ceftriaxone 50mg/kg IV q24hr) plus Vancomycin 15mg/kg IV q12h
Adult:
(Cefotaxime 2gm IV q4-8h or Ceftriaxone 2gm IV q24h) plus Vancomycin
(Cefotaxime 50mg/kg IV q8h and Ceftriaxone 50mg/kg IV q24hr) plus Vancomycin 15mg/kg IV q12h
(Cefotaxime 2gm IV q4-8h or Ceftriaxone 2gm IV q24h) plus Vancomycin
Pediatrics
Penicillin V 250mg PO BID x 10 days
Amoxicillin 50mg/kg PO once daily x 10 days
Adults
Penicillin V 500mg PO BID x 10 days
If compliance is unlikely
Benzathine Penicillin 25,000Units/kg IM (to a maximum of 1.2 million units) x 1 dose
If allergic to PCN
Clindamycin 300mg PO q8h x 10days
Penicillin V 250mg PO BID x 10 days
Amoxicillin 50mg/kg PO once daily x 10 days
Penicillin V 500mg PO BID x 10 days
If compliance is unlikely
Benzathine Penicillin 25,000Units/kg IM (to a maximum of 1.2 million units) x 1 dose
If allergic to PCN
Clindamycin 300mg PO q8h x 10days
Benzathine Penicillin 25,000Units/kg IM (to a maximum of 1.2 million units) x 1 dose
Clindamycin 300mg PO q8h x 10days
Topical nystatin
Acetaminophen
Local anesthetic lozenges
Treatment determined by severity of illness
Epinephrine 0.3mg 1:1,000 IM
Diphenhydramine 50mg IV
Ranitidine 150mg
Methylprednisolone 125mg IV
Epinephrine 0.3mg 1:1,000 IM
Diphenhydramine 50mg IV
Ranitidine 150mg
Methylprednisolone 125mg IV
Cover for allergic reaction with medications above
If true angioedema, will not resolve symptoms
Stop ACE inhibitor
See angioedema management
If true angioedema, will not resolve symptoms
Antihistamines IV
Hydrocortisone or dexamethasone IV
Uvulitis
Appendicitis 
Infectious
Appendicitis
Group A Streptococcus
Cervicitis
H. Influenza
Orchitis