Pregnancy: C (risk cannot be excluded)
Lactation: probably safe
Renal Dosing
Adult
GFR 20-50: give q24h
GFR < 20: give usual dose x1, then decrease dose 50% q24h
HD: give 100-200mg after dialysis
Pediatric
specific adjustment not defined though adjustment may be required
Hepatic Dosing
Adult
cirrhosis: max 400mg/24h
Pediatric
specific adjustment not defined though adjustment may be required
Adult
GFR 20-50: give q24h
GFR < 20: give usual dose x1, then decrease dose 50% q24h
HD: give 100-200mg after dialysis
Pediatric
specific adjustment not defined though adjustment may be required
GFR 20-50: give q24h
GFR < 20: give usual dose x1, then decrease dose 50% q24h
HD: give 100-200mg after dialysis
specific adjustment not defined though adjustment may be required
Adult
cirrhosis: max 400mg/24h
Pediatric
specific adjustment not defined though adjustment may be required
cirrhosis: max 400mg/24h
specific adjustment not defined though adjustment may be required
Ofloxacin
Gatifloxacin
Ciprofloxacin
Fosfomycin
Meropenem
Gemifloxacin
Linezolid
Moxifloxacin