Clostridium tetani spores enter skin through wound, make<unk> pasmin toxin
2001-2008 in US, 233 cases, 26 deaths
Mortality as high as 45%
Incubation is 2 to 56d
Spores found in soil and human and animal feces<unk>  prone wounds include contaminated lacerations, abrasions, puncture wounds; crush, avulsion, or frostbite injuries are also vulnerable to<unk>  
Preferentially binds GABA and glycinergic neurons and blocks pre-synaptic release
Motor neurons undergo sustained excitatory discharge, producing spasms
The majority of clinical<unk>  happen in the elderly.<unk>  prone wounds include contaminated lacerations, abrasions, puncture wounds; crush, avulsion, or frostbite injuries are also vulnerable to<unk>  
Preferentially binds GABA and glycinergic neurons and blocks pre-synaptic release
Motor neurons undergo sustained excitatory discharge, producing spasms
Motor neurons undergo sustained excitatory discharge, producing spasms
Acute tetanus
Herpes zoster oticus
Akathisia
Crotaline envenomation
Conversion disorder
Herpes zoster
Drug toxicity 
Stonefish envenomation