Major impairment in learning and memory plus impairment in handling complex tasks, impairment in reasoning ability, impaired spatial ability and orientation, or impaired language
Symptoms significantly interfere with work, usual social activities, relationships
Significant decline from previous level of functioning
Disturbances are insidious and progressive
Disturbances are not occurring exclusively during the course of delirium
Disturbances are not accounted for by major psychiatric diagnosis
Disturbances are not accounted for by systemic disease or another brain disease
Most common: Cholinesterase inhibitors, memantine hydrochloride, lipid lower agents, antiplatelet (except aspirin)
Others: hormone antagonists, leukotriene inhibitors, cytotoxic chemotherapy, immunomodulators
Dementia
D = drug-induced
Delirium
E = emotions 
Normal pressure hydrocephalus
M = metabolic and endocrine issues
Parkinson's disease
E = eyes and ears 