Pregnancy Rating: C
Lactation risk:<unk>  enters breast milk, caution should  be used when administering in a nursing woman.
Adult:
Gout flare treatment:
Use<unk>  to treat acute route flare is contraindicated in patients with renal impairment who are receiving<unk>  for prophylaxis.
CrCl 30-80 mL/minute: dose adjustment not required, monitor closely for adverse effects.
CrCl <30 mL/minute: consider dose reduction, should not repeat dose more frequently that every 14 days.
Dialysis: A single dose of 0.6mg, should not repeat dose more frequently that every 14 days.
Gout prophylaxis:
CrCl 30-80 mL/minute: dose adjustment not required, monitor closely for adverse effects.
CrCl <30 mL/minute: nitial dose: 0.3mg daily, titrate with caution, monitor closely for adverse effects.
Dialysis: 0.3mg twice weekly, monitor closely for adverse effects.
FMF:
CrCl 30-80 mL/minute: monitor closely for adverse effects, consider dosage reduction.
CrCl <30mL/minute: Initial dose: 0.3mg daily, titrate with caution, monitor closely for adverse effects.
Dialysis: a single dose of 0.3mg, titrate with caution, monitor closely for adverse effects.
Gout flare treatment:
Use<unk>  to treat acute route flare is contraindicated in patients with renal impairment who are receiving<unk>  for prophylaxis.
CrCl 30-80 mL/minute: dose adjustment not required, monitor closely for adverse effects.
CrCl <30 mL/minute: consider dose reduction, should not repeat dose more frequently that every 14 days.
Dialysis: A single dose of 0.6mg, should not repeat dose more frequently that every 14 days.
Gout prophylaxis:
CrCl 30-80 mL/minute: dose adjustment not required, monitor closely for adverse effects.
CrCl <30 mL/minute: nitial dose: 0.3mg daily, titrate with caution, monitor closely for adverse effects.
Dialysis: 0.3mg twice weekly, monitor closely for adverse effects.
FMF:
CrCl 30-80 mL/minute: monitor closely for adverse effects, consider dosage reduction.
CrCl <30mL/minute: Initial dose: 0.3mg daily, titrate with caution, monitor closely for adverse effects.
Dialysis: a single dose of 0.3mg, titrate with caution, monitor closely for adverse effects.
Use<unk>  to treat acute route flare is contraindicated in patients with renal impairment who are receiving<unk>  for prophylaxis.
CrCl 30-80 mL/minute: dose adjustment not required, monitor closely for adverse effects.
CrCl <30 mL/minute: consider dose reduction, should not repeat dose more frequently that every 14 days.
Dialysis: A single dose of 0.6mg, should not repeat dose more frequently that every 14 days.
CrCl 30-80 mL/minute: dose adjustment not required, monitor closely for adverse effects.
CrCl <30 mL/minute: nitial dose: 0.3mg daily, titrate with caution, monitor closely for adverse effects.
Dialysis: 0.3mg twice weekly, monitor closely for adverse effects.
CrCl 30-80 mL/minute: monitor closely for adverse effects, consider dosage reduction.
CrCl <30mL/minute: Initial dose: 0.3mg daily, titrate with caution, monitor closely for adverse effects.
Dialysis: a single dose of 0.3mg, titrate with caution, monitor closely for adverse effects.
Pediatric: Not defined
Adult:
Mild to moderate impairment: use with caution, closely monitor for adverse effects.
Severe impairment: consider dosage adjustment.
Pediatric: Not defined
Mild to moderate impairment: use with caution, closely monitor for adverse effects.
Severe impairment: consider dosage adjustment.
Colchicine
Diclofenac
Ketoprofen
Allopurinol
Acetaminophen
Ibuprofen
Celecoxib
Prednisolone