Prevention is key with ventilator lung protective settings
Management is the same as ARDS:
Continue mechanical ventilation
Apply lung protective settings (see Lung<unk>  Strategy section of Ventilation (Settings))
Treat underlying causes
Supportive care
Continue mechanical ventilation
Apply lung protective settings (see Lung<unk>  Strategy section of Ventilation (Settings))
Treat underlying causes
Supportive care
Maintain Plateau pressure ≤ 30 cm H20
Use tidal volume 6ml/kg of PBW (see EBQ:ARDSnet Trial)
Protective lung ventilation
Neuromuscular blockers may help.
High PEEP of 5 cm H20
Consider prone positioning
Limit FiO2 and maintain higher PEEP.
Accept SaO2 at "shoulder" of oxyhaemoglobin dissociation curve (SaO2 88-94%).
^Fully supported mode (rather than partially supported) on either volume (better studied) or pressure control (both acceptable).
Ventilator associated lung injury
ARDS
Ventilator associated pneumonia
Cardiogenic Pulmonary Edema
Iatrogenic pneumothorax
Acute exacerbation of idiopathic pulmonary fibrosis
Lung transplant complications
Pneumonia