Anaphylaxis(0.2% of patients), anaphylactoid reaction
Circulatory collapse, capillary leak, bradyarrhythmia, hypotension
Pulmonary edema
Flushing
Dyspnea
Nausea/vomiting
Protamine sulfate
Vitamin K
Fresh frozen plasma
Prothrombin complex concentrates
Tranexamic acid
Packed red blood cells
Desmopressin
EDTA