Acute polyneuropathy due to immune-mediated peripheral nerve myelin sheath destruction
Although there is often a motor component, patients can also present with sensory deficits.
Associated with viral or febrile illness, Campylobacter infection, or vaccination
Symptoms at worst 2-4wk after onset, then plateau for 2-4wk, then remit from wks-months
Associated with Campylobacter jejuni, cytomegalovirus, Epstein-Barr virus, and Mycoplasma pneumoniae
Guillain-Barre syndrome
Neuromuscular weakness
Lambert-Eaton myasthenic syndrome
Upper motor neuron:
Amyotrophic lateral sclerosis
CVA
Polymyositis
Hemorrhagic stroke