Disease involves multiple systems and thus management depends on presentating chief complaint.
Identify and treat hypocalcemia as these patients are at risk for seizures
Vitamin D supplementation may also be needed
Psychiatric Disorders (60%)
Thrombocytopenia (30%)
Hypothyroidism (20%)
Cholelithiasis (20%)
Vitamin D supplementation may also be needed
DiGeorge syndrome
Marfan syndrome
Kounis syndrome
Down syndrome
Ehlers-Danlos syndrome
Brash syndrome
Retinoic acid syndrome
Lown-Ganong-Levine syndrome