Fungal culture (Blood, sputum, bone marrow, liver or skin) : Broad based buds
Antigen test (Serum or urine)
Histopathology
Serologic testing
HIV testing
CXR: Alveolar infiltrates +/- cavitation, mass lesions, miliary or reticulo- or fibronodular pattern, pleural effusions, upper lobe infiltrate, perihilar lymph nodes
Chest CT: Nodules, consolidation +/- cavitation, tree-in-bud opacities, pleural effusion, lack hilar adenopathy
Xray of bone: Well-circumscribed osteolytic lesion
Xray vertebrae: Lytic lesion in anterior vertebral body and destruction of disc space
Bronchoscopy
Xray vertebrae: Lytic lesion in anterior vertebral body and destruction of disc space
Blastomycosis
Pneumonia
Sporotrichosis
Malignancy
Mucormycosis
Tuberculosis
Coccidioidomycosis
Histoplasmosis