Can be produced by any serotonergic medication
1 in 6 U.S. adults take at least one psychoactive medication
Majority of cases occur within therapeutic drug dosages
Most common cause is ingestion of foods high in L-Tryptophan while taking an MAOI. Second most common is ingestion of both<unk> RI and MAOI
Most common cause of death is severe hyperthermia<unk> RIs
SNRIs
Bupropion
Buspirone
TCAs
Lithium
Mirtazapine
Trazodone
Valproic acid
MAOIs (should have washout period of 2+ weeks prior to starting a<unk> RI)
Phenelzine
Selegiline
Tranylcypromine
Phenelzine
Selegiline
Tranylcypromine
Cocaine
Ecstasy (MDMA)
Methamphetamine
LSD
Fentanyl
Meperidine (Demerol)
Methadone
Tramadol
Metoclopramide
Ondansetron
Dextromethorphan
Oral decongestants (Pseudoephedrine)
St John’s Wort, Ginseng, Nutmeg, Yohimbe
Triptans
Ergot alkaloids
Bromocriptine
Linezolid
Carbamazepine
Cyclobenzaprine
L-tryptophan, 5-hydroxytryptophan
Methylene blue
Serotonin syndrome
Chorea
Cannabinoid hyperemesis syndrome
Sydenham's chorea
Cholinergic crisis
Neuroleptic malignant syndrome
Cocaine toxicity
Anticholinergic toxicity