Thrombosis (e.g. extremity phlebitis or dural sinus vein thrombosis)
Heparin IV/SQ followed by warfarin +/- ASA
Goal INR
Venous 2.0-3.0
Arterial 3.0
Recurrent 3.0-4.0
Heparin IV/SQ followed by warfarin +/- ASA
Goal INR
Venous 2.0-3.0
Arterial 3.0
Recurrent 3.0-4.0
Venous 2.0-3.0
Arterial 3.0
Recurrent 3.0-4.0
Miscarriage is common
Prophylaxis for most women
Patients with pregnancy loss
Prophylactic heparin and low-dose ASA
Patients with history of thrombosis
Therapeutic heparin
Prophylactic heparin and low-dose ASA
Therapeutic heparin
Eliminate risk factors (OCPs, smoking, hypertension and HL)
Low-dose ASA
Lupus anticoagulant
Too few
Factor VIII inhibitor
Thrombocytopenia
Factor V Leiden
Nonfunctional
Antiphospholipid syndrome
Aspirin