Results in a smallpox-like disease in humans.
The incubation period (interval from infection to onset of symptoms) of<unk>  can range from 5 to 21 days.
Typically presents clinically with fever, rash and swollen lymph nodes.
Mostly transmitted to people from wild animals such as rodents and primates, but human-to-human transmission also occurs
Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding
Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy.
Lymphadenopathy is a distinctive feature of<unk>  compared to other diseases that may initially appear similar (chickenpox, measles, smallpox).
Skin eruption usually begins within 1-3 days of appearance of fever.
The rash tends to be more concentrated on the face and extremities rather than on the trunk.
It affects the face (in 95% of cases), and palms of the hands and soles of the feet (in 75% of cases).
Also affected are oral mucous membranes (in 70% of cases), genitalia (30%), and conjunctivae (20%), as well as the cornea.
The rash evolves sequentially from macules to papules, vesicles, pustules, and finally, crusting, which dry up and fall off.
The number of the lesions varies from a few to several thousand.
In severe cases, lesions can coalesce until large sections of skin slough off.
Lymphadenopathy is a distinctive feature of<unk>  compared to other diseases that may initially appear similar (chickenpox, measles, smallpox).
The rash tends to be more concentrated on the face and extremities rather than on the trunk.
It affects the face (in 95% of cases), and palms of the hands and soles of the feet (in 75% of cases).
Also affected are oral mucous membranes (in 70% of cases), genitalia (30%), and conjunctivae (20%), as well as the cornea.
The rash evolves sequentially from macules to papules, vesicles, pustules, and finally, crusting, which dry up and fall off.
The number of the lesions varies from a few to several thousand.
In severe cases, lesions can coalesce until large sections of skin slough off.
In severe cases, lesions can coalesce until large sections of skin slough off.
Monkeypox
Smallpox
Ecstasy 
Chickenpox
Ethacrynic acid
Measles
Agent orange
Multiple Endocrine Neoplasia 