Sudden decrease in perfusion that may result in irreversible limb loss
Amputation occurs in 10%-15% of patients during hospitalization
Etiology may be thrombotic (80%) or embolic (20%)
Thrombosis occurs in vessels with existing atherosclerosis
Generally have formed collateral circulation
Embolism occurs in vessels usually free of atherosclerosis
Generally do not have existing collateral circulation
Results in higher level of limb<unk>  than thrombosis
Amputation occurs in 10%-15% of patients during hospitalization
Thrombosis occurs in vessels with existing atherosclerosis
Generally have formed collateral circulation
Embolism occurs in vessels usually free of atherosclerosis
Generally do not have existing collateral circulation
Results in higher level of limb<unk>  than thrombosis
Generally have formed collateral circulation
Generally do not have existing collateral circulation
Results in higher level of limb<unk>  than thrombosis
Acute arterial ischemia
Peripheral artery disease
Venous gangrene
Vascular injury
Wet gangrene
Missile embolus
Atheroembolism 
Dry gangrene