Pregnancy Rating: C
Lactation risk: Infant risk is minimal
Renal dosing:
Adjust dose/frequency based on serum drug levels if CrCl <79mL/min
CrCl <10: 15-25mg/kg q48h OR 3 times per week
CrCl 10-15: 10-25mg/kg q24-36h
Hemodialysis: 15-25mg/kg 3 times per week after HD
Hepatic dosing:
Adjust dose/frequency based on serum drug levels if CrCl <79mL/min
CrCl <10: 15-25mg/kg q48h OR 3 times per week
CrCl 10-15: 10-25mg/kg q24-36h
Hemodialysis: 15-25mg/kg 3 times per week after HD
Ethambutol
Isoniazid
Pyrazinamide
Rifamycins
Rifampin
Amikacin
Streptomycin
Moxifloxacin