Supportive care and patient reassurance
Sedation as needed with benzos
In severe cases, physostigmine 0.5–2.0 mg IV at a rate of no more than 1mg/min (adult dosing)
A second dose may be administered if necessary
Children should receive 0.02 mg/kg intravenously and the rate should not exceed 0.5 mg/min
Note that pyridostigmine does not cross the blood brain barrier, and is a poor agent for agitation, CNS features
A second dose may be administered if necessary
Children should receive 0.02 mg/kg intravenously and the rate should not exceed 0.5 mg/min
Note that pyridostigmine does not cross the blood brain barrier, and is a poor agent for agitation, CNS features
Jimson weed
Sympathomimetic toxicity
Tapeworm
Red, dry skin and absent bowel sounds favors anticholinergic toxicity
Amanita mushrooms
Encephalitis
Inocybe
Head trauma