Severe respiratory depression
Coma
Exacerbation of dehydration and electrolyte imbalances due to intestinal fluid retention secondary to inhibition of peristalsis
Bacterial overgrowth, release of bacterial endotoxins, sepsis
Toxic megacolon
Anticholinergic toxicity (hyperthermia, tachycardia, urinary retention, flushing, dry skin/mucous membranes), particularly in pediatric patients with Down's syndrome
Pancreatitis
Nausea/vomiting, abdominal discomfort
Blurred vision
Sedation
Dry skin or mouth
Diphenoxylate/atropine
Dicyclomine
Atropine
Doxylamine
Dimenhydrinate
Cefpodoxime
Homatropine
Physostigmine