20-30 mg/kg PO QD
Start: 20 mg/kg PO QD
Max: 40 mg/kg/day
Adjust dose by 5-10 mg/kg/day q3-6mo based on serum ferritin
Decrease dose 10 mg/kg/day if Cr >33% above baseline x2 weeks
Hold: Ferritin <500 mcg/L
Start: 20 mg/kg PO QD
Max: 40 mg/kg/day
Adjust dose by 5-10 mg/kg/day q3-6mo based on serum ferritin
Decrease dose 10 mg/kg/day if Cr >33% above baseline x2 weeks
Hold: Ferritin <500 mcg/L
10-20 mg/kg PO QD
Start: 10 mg/kg PO QD
Max: 20 mg/kg/day
Decrease dose 50% if Cr >33% above baseline x2 weeks
Interrupt treatment if already at 5 mg/kg/day
Hold: Ferritin <300 mcg/L or liver iron <3 mg Fe/g
Start: 10 mg/kg PO QD
Max: 20 mg/kg/day
Decrease dose 50% if Cr >33% above baseline x2 weeks
Interrupt treatment if already at 5 mg/kg/day
Hold: Ferritin <300 mcg/L or liver iron <3 mg Fe/g
Interrupt treatment if already at 5 mg/kg/day
Deferasirox
Succimer
Deferoxamine
Colestipol
Ulipristal
EDTA
Dimercaprol
Senna