Nonsurgical management
Necrotic tissue should be gently removed
Wide surgical debridement results in enlargement of ulcer
Medical management
Small ulcers
Topical steroids and/or steroid injections, silvadene compression dressings
Dapsone or minocycline PO
Severe ulcers
Corticosteroids
Immunologic treatment/biologics
IVIG, plasmapheresis
Necrotic tissue should be gently removed
Wide surgical debridement results in enlargement of ulcer
Small ulcers
Topical steroids and/or steroid injections, silvadene compression dressings
Dapsone or minocycline PO
Severe ulcers
Corticosteroids
Immunologic treatment/biologics
IVIG, plasmapheresis
Topical steroids and/or steroid injections, silvadene compression dressings
Dapsone or minocycline PO
Corticosteroids
Immunologic treatment/biologics
IVIG, plasmapheresis
Pyoderma gangrenosum
Systemic diseases
Erythema infectiosum
Neutrophilic dermatoses 
Cutaneous larva migrans
Calciphylaxis - very important to differentiate due to treatment
Purpura fulminans
Arterial/venous insufficiency