Arises from primitive ganglion cells of sympathetic nervous system
Synthesize and secrete catecholamines
Most common neoplasm in 1st yr of life
May arise anywhere along sympathetic nervous system
Adrenal gland (40%)
Abdomen (25%)
Chest (15%)
Mets are most common in lymph nodes, bone marrow, cortical bone, dura, orbits, liver, and skin
Adrenal gland (40%)
Abdomen (25%)
Chest (15%)
Neuroblastoma 
Wilms' tumor
Hepatoblastoma
Giant cell tumor
Lymphoma
Pheochromocytoma
Other adrenal gland tumor
Vestibular schwannoma