Abdominal pain
Diarrhea
Weight loss
Perianal fissures or fistulas
Arthritis
Peripheral arthritis
Migratory monoarticular or polyarticular
Ankylosing spondylitis
Pain/stiffness of spine, hips, neck, rib cage
Sacroiliitis
Low back pain with morning stiffness
Ocular
Uveitis
Acute blurring of vision, photophobia, pain, perilimbic scleral injection
Episcleritis
Eye burning or itching with out visual changes or pain; scleral and conj hyperemia
Dermatologic
Erythema nodosum
Painful, red, raised nodules on extensor surfaces of arms/legs
Pyoderma gangrenosum
Violaceous, ulcerative lesions with necrotic center found in pretibial region or trunk
Hepatobiliary
Cholelithiasis (33%)
Fatty liver
Autoimmune hepatitis
Primary sclerosing cholangitis
Cholangiocarcinoma
Renal
Increased risk for calcium oxalate stones due to hyperoxaluria
Vascular
Thromboembolism
Peripheral arthritis
Migratory monoarticular or polyarticular
Ankylosing spondylitis
Pain/stiffness of spine, hips, neck, rib cage
Sacroiliitis
Low back pain with morning stiffness
Migratory monoarticular or polyarticular
Pain/stiffness of spine, hips, neck, rib cage
Uveitis
Acute blurring of vision, photophobia, pain, perilimbic scleral injection
Episcleritis
Eye burning or itching with out visual changes or pain; scleral and conj hyperemia
Acute blurring of vision, photophobia, pain, perilimbic scleral injection
Eye burning or itching with out visual changes or pain; scleral and conj hyperemia
Erythema nodosum
Painful, red, raised nodules on extensor surfaces of arms/legs
Pyoderma gangrenosum
Violaceous, ulcerative lesions with necrotic center found in pretibial region or trunk
Painful, red, raised nodules on extensor surfaces of arms/legs
Violaceous, ulcerative lesions with necrotic center found in pretibial region or trunk
Cholelithiasis (33%)
Fatty liver
Autoimmune hepatitis
Primary sclerosing cholangitis
Cholangiocarcinoma
Increased risk for calcium oxalate stones due to hyperoxaluria
Thromboembolism
Crohn's disease
Viral gastroenteritis
Irritable bowel syndrome
Bacterial gastroenteritis
Ulcerative colitis
Campylobacter infections
Celiac disease
Clostridium difficile colitis