Acute febrile neutrophilic dermatosis
Rare skin condition
Usually affects age 30-60, but can happen in any age group
Classic<unk>  syndrome affects women > men
Unclear pathologenesis, but possibly factors include hypersensitivity reaction, cytokine dysregulation, or genetic susceptibility
Classical<unk>  syndrome, usually secondary to:
Infection: Typically 1 to 3 weeks following upper respiratory infection or gastrointestinal infection
Inflammatory bowel disease: Crohn's disease or ulcerative colitis
Pregnancy
Malignancy-associated<unk>  syndrome
Hematologic (~85%), most commonly acute myeloid leukemia
Solid tumor (~15%), most commonly carcinoma of GU organs, breasts, GI tract
Drug-induced<unk>  syndrome, most commonly granulocyte-colony stimulating factor (G-CSF)
Typically 2 weeks after drug exposure in patient without prior exposure
Fever and rash
Infection: Typically 1 to 3 weeks following upper respiratory infection or gastrointestinal infection
Inflammatory bowel disease: Crohn's disease or ulcerative colitis
Pregnancy
Hematologic (~85%), most commonly acute myeloid leukemia
Solid tumor (~15%), most commonly carcinoma of GU organs, breasts, GI tract
Typically 2 weeks after drug exposure in patient without prior exposure
Sweet's syndrome
Infectious
Staphylococcal scalded skin syndrome
Adenovirus
Rabies
Arbovirus
Drug rash
EBV