Prevention of<unk>  for those who are taking NSAIDs (with low cardiovascular risk) can be achieved by adding a proton pump inhibitor (PPI), an H2 antagonist, or misoprostol. NSAIDs of the COX-2 inhibitors type may reduce the rate of<unk> s when compared to non-selective NSAIDs. PPI is the most popular agent in<unk><unk>  prevention. However, there is no evidence that H2 antagonists can prevent stomach bleeding for those taking NSAIDs. Although misoprostol is effective in preventing<unk><unk> , its properties of promoting abortion and causing gastrointestinal distress limit its use. For those with high cardiovascular risk, naproxen with PPI can be a useful choice. Otherwise, low-dose aspirin, celecoxib, and PPI can also be used.
Peptic ulcer disease
Gallstone
Stress ulcer
Coronary artery disease
Acid peptic diseases
Stomach cancer
Gastric varices
Gastritis