Type II appears to be due to mutations in the transcription factor TWIST2 on chromosome 2. Type IV is due to mutations in the Cyp26c1 gene. Pathology Under the temporal lesions the skeletal muscle is almost in direct continuity with the epidermis.
Focal facial dermal dysplasia
Focal dermal hypoplasia
Congenital malformations of the dermatoglyphs
Inherited patterned lentiginosis
Congenital melanocytic nevus
Premature greying of hair
Subcutaneous granuloma annulare
Auricular hypertrichosis