The medical uses of<unk>  are the same as those of estradiol and other estrogens. Examples of indications for the drug include hormone therapy and hormonal contraception. In regard to the latter,<unk>  has been used in combination with medroxyprogesterone acetate as a combined injectable contraceptive. Along with estradiol valerate, estradiol undecylate, and estradiol benzoate,<unk>  is used as a form of high-dose estrogen therapy in feminizing hormone therapy for transgender women. The medication has been used to induce puberty in girls with delayed puberty due to hypogonadism.<unk>  is usually used at a dosage of 1 to 5 mg by intramuscular injection every 3 to 4 weeks in the treatment of menopausal symptoms such as hot flashes and vaginal atrophy, at a dosage of 1.5 to 2 mg by intramuscular injection once a month in the treatment of female hypoestrogenism due to hypogonadism, and at a dosage of 2 to 10 mg by intramuscular injection once every 1 or 2 weeks for hormone therapy in transgender women. The doses used to induce puberty in girls are 0.2 to 2.5 mg per month, gradually increased over a period of 4 years. Available forms<unk>  is and has been available as an oil solution for intramuscular injection provided in vials and ampoules at concentrations of 1, 3, and 5 mg/mL (and containing 5, 10, 15, 25, or 50 mg<unk>  total). The 1 and 3 mg/mL concentrations (containing 5 and 15 mg<unk>  total) have been discontinued in the United States, but the 5 mg/mL concentration (containing 25 mg<unk>  total) remains available. Aside from<unk> , the only other injectable estrogen formulations that remain available in the United States are estradiol valerate (10 mg/mL, 20 mg/mL, and 40 mg/mL in oil) and conjugated estrogens (25 mg/vial in solution). In addition to single-drug formulations,<unk>  has been marketed in combination with medroxyprogesterone acetate as a microcrystalline aqueous suspension (brand name Lunelle) and in combination with testosterone<unk>  as an oil solution (brand name Depo-Testadiol). 5-mL vials of Depo-Estradiol (5 mg/mL<unk>  in cottonseed oil solution for use by intramuscular injection) in the United States.
Estradiol cypionate
Estradiol dienantate
Estradiol undecylate
Estradiol enantate
Estradiol furoate
Estradiol dipropionate
Estradiol benzoate
Estradiol valerate