Clinical practice guidelines have recommended corticosteroids. People should be risk stratified using a MELD Score or Child-Pugh score. These scores are used to evaluate the severity of the liver disease based on several lab values. The greater the score, the more severe the disease. *Abstinence: Stopping further<unk> onsumption is the number one factor for recovery in patients with<unk> . *Nutrition Supplementation: Protein and calorie deficiencies are seen frequently in patients suffering from<unk> , and it negatively affects their outcomes. Improved nutrition has been shown to improve liver function and reduce incidences encephalopathy and infections. *Corticosteroids: These guidelines suggest that patients with a modified Maddrey's discriminant function score > 32 or hepatic encephalopathy should be considered for treatment with prednisolone 40 mg daily for four weeks followed by a taper. Models such as the Lille Model can be used to monitor for improvement or to consider alternative treatment. *Pentoxifylline: Systematic reviews comparing the treatment of pentoxifylline with corticosteroids show there is no benefit to treatment with pentoxifylline Potential for combined therapy: A large prospective study of over 1000 patients investigated whether prednisolone and pentoxifylline produced benefits when used alone or in combination. Pentoxifylline did not improve survival alone or in combination. Prednisolone gave a small reduction in mortality at 28 days but this did not reach significance, and there were no improvements in outcomes at 90 days or 1 year. *IV N-acetylcysteine: When used in conjunction with corticosteroids, improves survival at 28 days by decreasing rates of infection and hepatorenal syndrome. *Liver Transplantation: Early liver transplantation is ideal and helps to save lives. However, most transplant providers in the United States require a period of alcohol abstinence (typically 6 months) prior to transplant, but the ethics and science behind this are controversial.
Alcoholic hepatitis
Viral hepatitis
Ischemic hepatitis
Autoimmune hepatitis
Alcoholic liver disease
Fatty liver disease
Non-alcoholic fatty liver disease
Idiopathic granulomatous hepatitis