<unk>  is used to manage anti-diuretic hormone deficiency.<unk>  is used to treat diabetes insipidus related to low levels of antidiuretic hormone. It is available as Pressyn.<unk>  has off-label uses and is used in the treatment of<unk> odilatory shock, gastrointestinal bleeding, ventricular tachycardia and ventricular fibrillation.<unk>  agonists are used therapeutically in various conditions, and its long-acting synthetic analogue desmopressin is used in conditions featuring low<unk>  secretion, as well as for control of bleeding (in some forms of von Willebrand disease and in mild haemophilia A) and in extreme cases of bedwetting by children. Terlipressin and related analogues are used as<unk> oconstrictors in certain conditions. Use of<unk>  analogues for esophageal varices commenced in 1970.<unk>  infusions are also used as second line therapy for septic shock patients not responding to fluid resuscitation or infusions of catecholamines (e.g., dopamine or norepinephrine) to increase the blood pressure while sparing the use of catecholamines. These argipressins have much shorter elimination half-life (around 20 minutes) comparing to synthetic non-arginine<unk> es with much longer elimination half-life of many hours. Further, argipressins act on<unk> ,<unk> b, and V2 receptors which consequently lead to higher eGFR and lower<unk> cular resistance in the lungs. A number of injectable arginine<unk> s are currently in clinical use in the United States and in Europe. Pharmacokinetics<unk>  is administered through an intravenous device, intramuscular injection or a subcutaneous injection. The duration of action depends on the mode of administration and ranges from thirty minutes to two hours. It has a half life of ten to twenty minutes. It is widely distributed throughout the body and remains in the extracellular fluid. It is degraded by the liver and excreted through the kidneys. Arginin<unk> s for use in septic shock are intended for intravenous use only. Side effects The most common side effects during treatment with<unk>  are dizziness, angina, chest pain, abdominal cramps, heartburn, nausea, vomiting, trembling, fever, water intoxication, pounding sensation in the head, diarrhoea, sweating, paleness, and flatulence. The most severe adverse reactions are myocardial infarction and hypersensitivity. Contraindications The use of lysine<unk>  is contraindicated in the presence of hypersensitivity to beef or pork proteins, increased BUN and chronic kidney failure. It is recommended that it be cautiously used in instances of perioperative polyuria, sensitivity to the drug, asthma, seizures, heart failure, a comatose state, migraine headaches, and cardiovascular disease. Interactions *alcohol - may lower the antidiuretic effect *carbamazepine, chloropropamide, clofibrate, tricyclic antidepressants and fludrocortisone may raise the diuretic effect *lithium, demeclocycline, heparin or norepinephrine may lower the antidiuretic effect *vasopressor effect may be higher with the concurrent use of ganglionic blocking medications
Vasopressin
Pentostatin
Prorenin
Incretin
Bryostatin
Orexin
Angiotensin II 
Endrin