<unk> , sold under the brand name Zosyn among others, is a combination medication containing the antibiotic<unk>  and the β-lactamase inhibitor tazobactam. The combination has activity against many Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa. It is used to treat pelvic inflammatory disease, intra-abdominal infection, pneumonia, cellulitis, and sepsis. It is given by injection into a vein. Common adverse effects include headache, trouble sleeping, rash, nausea, constipation, and diarrhea. Serious adverse effects include Clostridium difficile infection and allergic reactions including anaphylaxis. Those who are allergic to other β-lactam are more likely to be allergic to<unk> . Use in pregnancy or breastfeeding appears to generally be safe. It usually results in bacterial death through blocking their ability to make a cell wall.<unk>  was approved for medical use in the United States in 1993. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
Piperacillin/tazobactam
Ceftazidime/avibactam
Imipenem/cilastatin
Imipenem/cilastatin/relebactam
Ampicillin/sulbactam
Ceftolozane/tazobactam
Meropenem
Resistin