There is a deficiency of malate in patients because<unk>  enzyme cannot convert<unk>  into it, therefore treatment is with oral malic acid which allows the Krebs cycle to continue, and eventually make ATP.
Fumarase deficiency
Enolase deficiency
Dihydropyrimidine dehydrogenase deficiency
Glutaminase deficiency
Phosphofructokinase deficiency
Hexokinase deficiency
Aldolase A deficiency
Transaldolase deficiency