<unk>  are a family of cells that are selected or engineered to accurately<unk> the genetics of a specific patient population, in vitro. They are provided with a genetically matched 'normal cell' to provide an<unk>  system to research disease biology and novel therapeutic agents. They can be used to<unk> any disease with a genetic foundation. Cancer is one such disease for which<unk>  have been widely used.
Isogenic human disease models
Animal disease model
Research into centenarians
Parkinson's disease clinical research
Alternatives to animal testing
Gain-of-function research
Human experimentation in North Korea
Rare disease assumption