It is usually seen when a physician performs ophthalmoscopy, during which a<unk>  will appear bright, refractile, and yellow. It is caused by an embolus lodged within the retinal vessel that originated from an atheromatous<unk>  in a more proximal (upstream) vessel, usually the internal carotid artery. It is often an indication of a previous ischemic episode in the eye and is a sign of severe atherosclerosis.
Hollenhorst plaque
Janeway lesion
Cameron lesions
Charlotte's Web 
Hill–Sachs lesion
Forchheimer spots
Lichtenberg figure
Elschnig spots