<unk>  (VAPI) also known as<unk><unk>  lung injury (VALI) or e-cigarette, or<unk> , product use<unk>  lung injury (E/VALI), is an umbrella term, used to describe lung diseases<unk>  with the use of<unk>  products that can be severe and life-threatening. Symptoms can initially mimic common<unk>  diagnoses, such as pneumonia, but sufferers typically do not respond to antibiotic therapy. Differential diagnoses have overlapping features with VAPI, including COVID-19. Sufferers usually present for care within a few days to weeks of symptom onset. Starting, in September 2019, the US Centers for Disease Control and Prevention (CDC) reported on a nation-wide outbreak of severe lung disease linked to<unk> , or the process of inhaling aerosolized substances with battery-operated electronic cigarettes (e-cigarettes), ciga-likes, or vape mods. The cases of lung injury date back to at least April 2019. , 2,758 cases of VAPI have been reported to the CDC, with 64 confirmed deaths. All CDC-reported cases of VAPI involved a history of using e-cigarette, or<unk> , products, with most samples having tested positive for tetrahydrocannabinol (THC) by the US FDA and most patients reporting a history of using a THC-containing product. CDC data show that the outbreak peaked in September 2019, and declined steadily to a low level through January 2020. In late February 2020, a CDC-authored article in the NEJM stated that the VAPI outbreak was "driven by the use of THC-containing products from informal and illicit sources." However, due to the COVID-19 pandemic, that exceeded 1 million worldwide deaths in October 2020, it is now possible that shared<unk>  devices spread COVID-19. Several organizations, including the Purdue University, and Public Health England (PHE) strongly advises against sharing vapes. The CDC has stated that the THC cutting agent vitamin E acetate is very strongly implicated in VAPI, but evidence was not sufficient to rule out a contribution from other chemicals of concern to VAPI as of January 2020.
Vaping-associated pulmonary injury
Ventilator-associated lung injury
Swimming-induced pulmonary edema
Occult pneumonia
Ventilator-associated pneumonia
Hospital-acquired pneumonia
Acute exacerbation of chronic obstructive pulmonary disease
Hantavirus pulmonary syndrome