Most of the symptoms of<unk>  result from an impaired regulation of the blood supply. How these symptoms affect the patient depends on to which organs or body parts blood supply is inhibited. Typical symptoms of<unk>  are cold hands or feet, low blood pressure, occasional white and red patches on the face or neck, and migraine-like pain or a feeling of pressure behind the upper eyelid. In addition, there are symptoms not directly resulting from dysregulations of the blood supply, such as a prolonged time needed to fall asleep, a reduced feeling of thirst, and high sensitivity not only to cold but also to odors, vibrations, psychological stress, or certain medications (e.g., calcium antagonists, beta blockers). Pain and muscle spasms are common. In many people with glaucoma, the cause of the disease is perfusion issues of the optic nerve and retina, while intraocular pressure is normal. Many patients with normal tension glaucoma have a basic constitution, which corresponds to the<unk> . Some of its features were formerly summarized under the term "primary vascular dysregulation<unk> ". Signs of<unk>  include: * cold hands or feet, or both * arterial hypotension * lower body mass index * decreased feeling of thirst * prolongation of time to fall asleep * increased sensitivity to pain and odors * sensitivity to certain drugs * migraine * tinnitus * reversible patchy white or red discoloration of the skin * excessive response to mental or physical stimuli such as stress or cold The disease is more prevalent in the following groups: * in women compared to men * in people with lower blood pressure * in Asians compared with Caucasians * in academics compared with blue collar-workers People with<unk>  sleep poorly and have a decreased sensation of thirst.
Flammer syndrome
Fryns-Aftimos syndrome
Bogart–Bacall syndrome
Teunissen–Cremers syndrome
Char syndrome
Helsmoortel-Van der Aa syndrome
Jeavons syndrome
Keutel syndrome