Congenital In fetal and neonatal life the<unk> al plates are remodeled. The malformations can be atretic or fibrocystic. Atretic causes * Intrahepatic<unk> <unk>  atresia (Alagille syndrome) (ALGS2 MIM:610205 and ALGS1 MIM:118450) * Extrahepatic<unk> <unk>  atresia Fibrocystic causes * Autosomal recessive polycystic kidney disease * Congential hepatic fibrosis * Caroli's disease * Von Meyenburg complex Chromosomal associations * Trisomy 17, 18 and 21 Genetic associations * Cystic fibrosis * Alpha 1 antitrypsin deficiency * Trihydroxycoprostanic acidemia * Byler's disease Immunologic associations<unk> <unk>  injury and loss can result from autoimmune destruction. T cells recognize biliary epithelial cell antigens causing injury and eventual atresia. Other causes * Primary biliary cirrhosis * Primary sclerosing cholangitis * Hodgkin's lymphoma * Chronic graft-versus-host disease * Drugs(chlorpromazine)/Toxins * Ischemia
Vanishing bile duct syndrome
Biliary atresia
Congenital hepatic fibrosis
Progressive familial intrahepatic cholestasis
Neonatal cholestasis
Toriello–Carey syndrome
Rubinstein–Taybi syndrome
Adams–Oliver syndrome