<unk>  () is a complex syndrome associated with an underlying illness causing ongoing muscle loss that is not entirely reversed with nutritional supplementation. A range of diseases can cause<unk> , most commonly cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease and AIDS. Systemic inflammation from these conditions can cause detrimental changes to metabolism and body composition. In contrast to weight loss from inadequate caloric intake,<unk>  causes mostly muscle loss instead of fat loss. Diagnosis of<unk>  can be difficult due to the lack of well-established diagnostic criteria.<unk>  can improve with treatment of the underlying illness but other treatment approaches have limited benefit.<unk>  is associated with increased mortality and poor quality of life. The term is from Greek κακός kakos, "bad", and ἕξις hexis, "condition".
Cachexia
Neurosis
Fatigue
Heat intolerance
Xerostomia
Anorexia 
Thermophobia
Sedation