Resection of the tumor is the ideal treatment and results in correction of hypophosphatemia (and low calcitriol levels) within hours of resection. Resolution of skeletal abnormalities may take many months. If the tumor cannot be located, begin treatment with calcitriol (1-3 µg/day) and phosphate supplementation (1-4 g/day in divided doses). Tumors that express somatostatin receptors may respond to treatment with octreotide. If hypophosphatemia persists despite calcitriol and phosphate supplementation, administration of cinacalcet has been shown to be useful.
Oncogenic osteomalacia
Metabolic bone disease
Endocrine bone disease
Vitamin D toxicity
Secondary hyperparathyroidism
Steroid-induced osteoporosis
Tertiary hyperparathyroidism
Normophosphatemic familial tumoral calcinosis