DEB is caused by genetic defects (or mutations) within the human COL7A1 gene encoding the protein<unk> VII collagen (collagen VII). DEB-causing mutations can be either dominant or recessive. Most families with family members with this condition have distinct mutations. Collagen VII is a very large molecule (300 kDa) that dimerizes to form a semicircular looping structure: the anchoring fibril. Anchoring fibrils are thought to form a structural link between the epidermal basement membrane and the fibrillar collagens in the upper dermis.
types of Epidermolysis bullosa
complications of Epidermolysis bullosa
symptom of Epidermolysis bullosa
medical cause of Roseola
medical cause of Onychomycosis
medical cause of Angular cheilitis
complications of Rosacea
complications of Toxic epidermal necrolysis