<unk>  of all infectious<unk> s, worldwide in 2004, measured in disability-adjusted life years<unk>  of non-communicable<unk> s, worldwide in 2004, measured in disability-adjusted life years<unk>  is the impact of a health problem as measured by financial cost, mortality, morbidity, or other indicators. It is often quantified in terms of quality-adjusted life years (QALYs) or disability-adjusted life years (DALYs). Both of these metrics quantify the number of years lost due to disability (YLDs), sometimes also known as years lost due to<unk>  or years lived with disability/disease. One DALY can be thought of as one year of healthy life lost, and the overall<unk>  can be thought of as a measure of the gap between current health status and the ideal health status (where the individual lives to old age free from<unk>  and disability). According to an article published in The Lancet in June 2015, low back pain and major depressive disorder were among the top ten causes of YLDs and were the cause of more health loss than diabetes, chronic obstructive pulmonary<unk> , and asthma combined. The study based on data from 188 countries, considered to be the largest and most detailed analysis to quantify levels, patterns, and trends in ill health and disability, concluded that "the proportion of disability-adjusted life years due to YLDs increased globally from 21.1% in 1990 to 31.2% in 2013." The environmental<unk>  of<unk>  is defined as the number of DALYs that can be attributed to environmental factors. Similarly, the work-related<unk>  of<unk>  is defined as the number of deaths and DALYs that can be attributed to occupational risk factors to human health. These measures allow for comparison of<unk> s, and have also been used to forecast the possible impacts of health interventions. By 2014 DALYs per head were "40% higher in low-income and middle-income regions." The World Health Organization (WHO) has provided a set of detailed guidelines for measuring<unk>  at the local or national level. In 2004, the health issue leading to the highest YLD for both men and women was unipolar depression; in 2010, it was lower back pain. According to an article in The Lancet published in November 2014, disorders in those aged 60 years and older represent "23% of the total global<unk>  of<unk> " and leading contributors to<unk>  in this group in 2014 were "cardiovascular<unk> s (30.3%), malignant neoplasms (15.1%), chronic respiratory<unk> s (9.5%), musculoskeletal<unk> s (7.5%), and neurological and mental disorders (6.6%)."
Disease burden
Cancer survival rates
Quality of life
Quality of life 
Mortality rate
Nutritional value
Risk of mortality
Case fatality rate