<unk>  (GDT) was introduced by Emanuel P. Rivers in The New England Journal of Medicine in 2001 and is a technique used in critical care medicine involving intensive monitoring and aggressive management of perioperative hemodynamics in patients with a high risk of morbidity and mortality. In cardiac surgery,<unk> -directed therapy has proved effective when commenced after surgery. The combination of GDT and Point-of-Care Testing has demonstrated a marked decrease in mortality for patients undergoing congenital heart surgery. Furthermore, a reduction in morbidity and mortality has been associated with GDT techniques when used in conjunction with an electronic medical record.<unk>  is a more specific form of therapy used for the treatment of severe sepsis and septic shock. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with an increased oxygen demand before surgery. Three trials published in 2014/2015 have shown that<unk>  should be abandoned.
Early goal-directed therapy
Minimized extracorporeal circulation
Maximum medical improvement
Palliative sedation
Early appropriate care
Directed therapy
Antimicrobial stewardship
Target controlled infusion