There are two primary types of<unk> : squamous-cell carcinoma and adenocarcinoma. * Squamous-cell carcinoma of the vagina arises from the squamous cells (epithelium) that line the vagina. This is the most common type of<unk> . It is found most often in women aged 60 or older. * Vaginal adenocarcinoma arises from the glandular (secretory) cells in the lining of the vagina. Adenocarcinoma is more likely to spread to the lungs and lymph nodes. * Clear cell adenocarcinoma occurs in a small percentage of women (termed "DES-Daughters") born between 1938 and 1973 (later outside the United States) that were exposed to the drug diethylstilbestrol (DES) in utero. DES was prescribed to 5 to 10 million mothers period to prevent possible miscarriages and premature births. Typically, women develop DES-related adenocarcinoma before age 30, but increasing evidence suggests possible effects or cancers (including other forms of vaginal glandular tumors) at a later age. DES-exposure in women is also linked to various infertility and pregnancy complications. Daughters exposed to DES in utero may also have an increased risk of moderate/severe cervical squamous cell dysplasia and an increased risk of breast cancer. Approximately one in 1,000 (0.1%) DES daughters will be diagnosed with clear cell adenocarcinoma. The risk is virtually non-existent among premenopausal women not exposed to DES. * Vaginal germ cell tumors (primarily teratoma and endodermal sinus tumor) are rare. They are found most often in infants and children. * Sarcoma botryoides, a rhabdomyosarcoma also is found most often in infants and children. * Vaginal melanoma, a melanoma that appears in the vagina. File:Diagram showing stage 1<unk>  CRUK 194.Stage 1<unk>  File:Diagram showing stage 2<unk>  CRUK 210.Stage 2<unk>  File:Diagram showing stage 3<unk>  CRUK 223.Stage 3<unk>  File:Diagram showing stage 4A<unk>  CRUK 237.Stage 4A<unk>  File:Diagram showing stage 4B<unk>  CRUK 240.Stage 4B<unk>
Vaginal cancer
Uterine prolapse
Cervical cancer
Uterine cancer
Pyometra
Vaginal melanoma
Endometrial cancer
Vaginal disease