Many affected individuals have yellowing of the skin and eyes (jaundice) and an enlarged liver and spleen (hepatosplenomegaly). This condition also causes the body to absorb too much iron, which builds up and can damage tissues and organs. In particular, iron overload can lead to an abnormal heart rhythm (arrhythmia), congestive heart failure, diabetes, and chronic liver disease (cirrhosis). Rarely, people with<unk> ype I are born with skeletal abnormalities, most often involving the fingers and/or toes.
Congenital dyserythropoietic anemia type I
Diamond–Blackfan anemia
Congenital hypoplastic anemia
Paroxysmal nocturnal hemoglobinuria
Hereditary spherocytosis
Beta thalassemia
Twin anemia-polycythemia sequence
Hereditary elliptocytosis