The protein is a determinant for the Indian blood group system. *<unk> , along with CD25, is used to track early T cell development in the thymus. *<unk>  expression is an indicative marker for effector-memory T-cells. Memory cell proliferation (activation) can also be assayed in vitro with CFSE chemical tagging. In addition, variations in<unk>  are reported as cell surface markers for some breast and prostate cancer stem cells. In breast cancer research<unk> +/CD24- expression is commonly used as a marker for breast CSCs and is used to sort breast cancer cells into a population enriched in cells with stem-like characteristics and has been seen as an indicator of increased survival time in epithelial ovarian cancer patients. Endometrial cells in women with endometriosis demonstrate increased expression of splice variants of<unk> , and increased adherence to peritoneal cells.<unk>  variant isoforms are also relevant to the progression of head and neck squamous cell carcinoma. Monoclonal antibodies against<unk>  variants include bivatuzumab for v6.
CD44
CD74
CD22
CD23
CD80
CDV3 
CD137
CD86