The evolution of<unk>  is highly unpredictable and is characterized by modulation of its severity and variable rate of progression across individuals. While instances of total recovery are observed, the condition is often persistent and lesions can reappear even after treatment. Factors that might affect the clinical course of the condition include: the HPV genotype, the age at onset, the elapsed time between the diagnosis and first treatment in addition to previous medical procedures. Other factors, albeit controversial, such as smoking or the presence of gastroesophageal reflux disease might also play a role in the progression of the disease. The papillomas can travel past the larynx and infect extralaryngeal sites. In more aggressive cases, infection of the lungs can occur with progressive airway obstruction. Although rare (less than 1% of people with<unk> , transformation from a benign form to a malignant form is also observed. Death can result from these complications (morbidity rate is around 1–2%).
Laryngeal papillomatosis
Laryngeal cyst
Otic polyp
Oral mucocele
Nasopharyngeal cyst
Epiglottitis
Vulvitis
Tuberculous gumma