There are several notable drug interactions with<unk>  Certain selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, paroxetine, and sertraline may increase the GABAA receptor-related central depressant effects of<unk> by enhancing its conversion into 5α-dihydroprogesterone and allopregnanolone via activation of 3α-HSD.<unk> potentiates the sedative effects of benzodiazepines and alcohol. Notably, there is a case report of<unk> abuse alone with very high doses. 5α-Reductase inhibitors such as finasteride and dutasteride inhibit the conversion of<unk> into the inhibitory neurosteroid allopregnanolone, and for this reason, may have the potential to reduce the sedative and related effects of<unk> <unk> is a weak but significant agonist of the pregnane X receptor (PXR), and has been found to induce several hepatic cytochrome P450 enzymes, such as CYP3A4, especially when concentrations are high, such as with pregnancy range levels. As such,<unk> may have the potential to accelerate the metabolism of various medications.
Progesterone 
Estrogen 
Estrogen
Androgen
Estradiol 
Estradiol
Methyltestosterone
Progestogen