The prefrontal cortex<unk>  is a state of decreased cerebral blood flow (CBF) in the prefrontal cortex of the brain.<unk>  is symptomatic of several neurological medical conditions, such as schizophrenia, attention deficit hyperactivity disorder (ADHD), bipolar disorder, and major depressive disorder. This condition was initially described by Ingvar and Franzén in 1974, through the use of xenon blood flow technique with 32 detectors to image the brains of patients with schizophrenia. This finding was confirmed in subsequent studies using the improved spatial resolution of positron emission tomography with the fluorodeoxyglucose (18F-FDG) tracer. Subsequent neuroimaging work has shown that the decreases in prefrontal CBF are localized to the medial, lateral, and orbital portions of the prefrontal cortex.<unk>  is thought to contribute to the negative symptoms of schizophrenia.
Hypofrontality
Neurodiversity
Hysteresivity
Codependency
Asociality
Social degeneration
Genetic exceptionalism
Oncogene addiction