The diagnosis is based on age less than forty, amenorrhea for four months or more, and two elevated serum follicle-stimulating hormone (FSH) measurements at one-month intervals. The anterior pituitary secretes FSH and LH at high levels to try to increase the low estrogen levels that are due to the dysfunction of the ovaries. Typical FSH in<unk>  patients is over 40 mlU/ml (post-menopausal range).
Primary ovarian insufficiency
Functional hypothalamic amenorrhea
Gonadotropin-resistant ovary syndrome
Androgen insufficiency syndrome
Hypergonadotropic hypergonadism
Polycystic ovary syndrome
Anovulation
Lactational amenorrhea