When used excessively,<unk>  like any other topical anesthetic used in the eye and on mucous membranes (like for example tetracaine, proxymetacaine and proparacaine) can cause irritation, hypersensitivity, anaphylaxis, irreversible corneal damage and even complete destruction of the cornea. (Excessive use means several times a day during several days or even weeks.)
Oxybuprocaine
Proxymetacaine
Noribogaine
Ibogaine
Procaine
Tetracaine
Levobupivacaine
Trospium chloride