The reason for the presence of anti-AQP4 autoantibodies is currently unknown. Some researchers have pointed out that it could be paraneoplastic. It seems also clear that lupus can produce NMO-IgG autoantibodies sometimes, leading to some cases of lupus-derived NMO.
Anti-AQP4 disease
Adult polyglucosan body disease
Akureyri disease
Anti-NMDA receptor encephalitis
MGUS polyneuropathy
Familial amyloid neuropathy
Anti-VGKC-complex encephalitis
Light chain deposition disease