A typical CPAP machine houses the air pump in a case lined with sound-absorbing material for quieter operation. A hose carries the<unk> zed air to a face mask or nasal pillow. The Sullivan V Plus, a typical mid-1990s CPAP (the mask is more modern). A typical full face CPAP mask. CPAP therapy breaks the cycle of OSA The main indications for<unk>  are congestive heart failure and chronic obstructive pulmonary disease. There is some evidence of benefit for those with hypoxia and community acquired pneumonia.<unk>  ventilation is often used for patients who have acute type 1 or 2 respiratory failure. Usually<unk>  ventilation will be reserved for the subset of patients for whom oxygen delivered via a face mask is deemed insufficient or deleterious to health (see retention). Usually, patients on<unk>  ventilation will be closely monitored in an intensive care unit, high-dependency unit, coronary care unit or specialist respiratory unit. The most common conditions for which<unk>  ventilation is used in hospital are congestive cardiac failure and acute exacerbation of obstructive airway disease, most notably exacerbations of COPD and asthma. It is not used in cases where the airway may be compromised, or consciousness is impaired. CPAP is also used to assist premature babies with breathing in the NICU setting. The mask required to deliver CPAP must have an effective seal, and be held on very securely. The "nasal pillow" mask maintains its seal by being inserted slightly into the nostrils and being held in place by various straps around the head. Some full-face masks "float" on the face like a hover-craft, with thin, soft, flexible "curtains" ensuring less skin abrasion, and the possibility of coughing and yawning. Some people may find wearing a CPAP mask uncomfortable or constricting: eyeglass wearers and bearded men may prefer the nasal-pillow type of mask. Breathing out against the positive<unk>  resistance (the expiratory<unk>  component, or EPAP) may also feel unpleasant to some patients. These factors lead to inability to continue treatment due to patient intolerance in about 20% of cases where it is initiated. Some machines have<unk>  relief technologies that makes sleep therapy more comfortable by reducing<unk>  at the beginning of exhalation and returning to therapeutic<unk>  just before inhalation. The level of<unk>  relief is varied based on the patient's expiratory flow, making breathing out against the<unk>  less difficult. Those who suffer an anxiety disorder or claustrophobia are less likely to tolerate<unk>  treatment. Sometimes medication will be given to assist with the anxiety caused by<unk>  ventilation. Unlike<unk>  used at home to splint the tongue and pharynx,<unk>  is used in hospital to improve the ability of the lungs to exchange oxygen and carbon dioxide, and to decrease the work of breathing (the energy expended moving air into and out of the alveoli). This is because: * During inspiration, the inspiratory<unk> , or<unk> , forces air into the lungs—thus less work is required from the respiratory muscles. * The bronchioles and alveoli are prevented from collapsing at the end of expiration. If these small airways and alveoli are allowed to collapse, significant<unk> s are required to re-expand them. This can be explained using the Young–Laplace equation (which also explains why the hardest part of blowing up a balloon is the first breath). * Entire regions of the lung that would otherwise be collapsed are forced and held open. This process is called recruitment. Usually these collapsed regions of lung will have some blood flow (although reduced). Because these areas of lung are not being ventilated, the blood passing through these areas is not able to efficiently exchange oxygen and carbon dioxide. This is called ventilation–perfusion (or V/Q) mismatch. The recruitment reduces ventilation–perfusion mismatch. *Common non-Continuous<unk>  device.The amount of air remaining in the lungs at the end of a breath is greater (this is called the functional residual capacity). The chest and lungs are therefore more expanded. From this more expanded resting position, less work is required to inspire. This is due to the non-linear compliance–volume curve of the lung.
Positive airway pressure
Continuous positive airway pressure
Mechanical ventilation
Negative pressure ventilator
High-frequency ventilation
Non-invasive ventilation
Artificial ventilation
Airway clearance therapy