Pharmacodynamics Whereas 11-ketoprogesterone and 11β-hydroxyprogesterone are virtually devoid of progestogenic activity (although 11β-hydroxyprogesterone has been reported to possess about 1% of the progestogenic activity of progesterone), the progestogenic activity of BKP is restored and is in fact relatively high. In contrast, 9α-fluoro-11β-hydroxyprogesterone has much lower progestogenic activity with only about 8 times that of 11β-hydroxyprogesterone. In addition, whereas 9α-fluoro-11β-hydroxyprogesterone has pronounced mineralocorticoid effects, BKP lacks such effects. BKP has been described as a weaker progestogen. It has been used at doses of as much as 300 mg orally per day. In addition to its activity as a progestogen, BKP has glucocorticoid activity. Pharmacokinetics The pharmacokinetics of BKP have been reviewed.
Bromoketoprogesterone
Retroprogesterone
Haloprogesterone
Vinyltestosterone
Hydroxyprogesterone acetate
Estradiol enantate
Estradiol dienantate
Hydroxyprogesterone heptanoate