Many over-the-counter and prescription-only medications contain<unk> . Because of its wide availability paired with comparably high toxicity, (compared to ibuprofen and aspirin) there is a much higher potential for overdose.<unk>  toxicity is one of the most common causes of poisoning worldwide. In the United States, the United Kingdom, Australia, and New Zealand,<unk>  is the most common cause of drug overdoses. Additionally, in both the United States and the United Kingdom it is the most common cause of acute liver failure. In England and Wales an estimated 41,200 cases of<unk>  occurred in 1989 to 1990, with a mortality of 0.40%. It is estimated that 150 to 200 deaths and 15 to 20 liver transplants occur as a result of poisoning each year in England and Wales.<unk>  overdose results in more calls to poison control centers in the US than overdose of any other pharmacological substance, accounting for more than 100,000 calls, as well as 56,000 emergency room visits, 2,600 hospitalizations, and 458 deaths due to acute liver failure per year. A study of cases of acute liver failure between November 2000 and October 2004 by the Centers for Disease Control and Prevention in the USA found that<unk>  was the cause of 41% of all cases in adults, and 25% of cases in children.
Paracetamol poisoning
Alcoholism
Carbamate poisoning
Viral hepatitis
Salicylate poisoning
Gastroenteritis
Cyanide poisoning
Secondary poisoning