A<unk>  is a type of enzyme inhibitor that blocks the action of one or more<unk><unk> s.<unk><unk> s are enzymes that add a phosphate (PO4) group to a<unk> , and can modulate its function. The phosphate groups are usually added to serine, threonine, or tyrosine amino acids on the<unk> : most<unk> s act on both serine and threonine, the tyrosine<unk> s act on tyrosine, and a number (dual-specificity<unk> s) act on all three. There are also<unk><unk> s that phosphorylate other amino acids, including histidine<unk> s that phosphorylate histidine residues. Phosphorylation regulates many biological processes, and<unk> s can be used to treat diseases due to hyperactive<unk><unk> s (including mutant or overexpressed<unk> s in cancer) or to modulate cell functions to overcome other disease drivers.
Protein kinase inhibitor
CDK inhibitor
Histone deacetylase inhibitor
COX-2 inhibitor
Reuptake inhibitor
Growth factor receptor inhibitor
Endopeptidase inhibitor
C-Met inhibitor