<unk>  has an anti-hyperglycaemic activity.<unk>  is a sulfonylurea and can therefore lower the blood glucose levels. Sulfonylureas can bind to receptors at β-pancreatic cells which are specific for sulfonylurea binding. When a sulfonylurea binds to its receptor, the ATP-dependent channels for K+ ions will be blocked. Therefore, the flow of K+ ions into the β-pancreatic cell will stop and the cell membrane becomes depolarized. As a result, calcium ions will flow into the cell and that will then cause the contraction of actomyosin filaments which are responsible for the exocytosis of insulin. Finally, the increased secretion of insulin can then lead to a decrease in the blood glucose level.
Glybuzole
Glysobuzole
Amivantamab
Lepra 
Memantine
Rilonacept
Nusinersen
Riluzole