The cause of FIRES is not known. There are some common clinical symptoms, such as onset after a nonspecific<unk>  illness, gastrointestinal illness, or upper respiratory<unk> . This prior illness is often cleared 1–14 days prior to the patient's first seizures. There are theories of an immunological source, a genetic predisposition, and an inflammation-mediated process, but the definite cause is unknown. It is more common in boys more than girls.
Febrile infection-related epilepsy syndrome
Sudden unexpected death in epilepsy
Neuroleptic malignant syndrome
Viral encephalitis
Musicogenic epilepsy
Post-traumatic epilepsy
Autoimmune encephalitis
Idiopathic childhood occipital epilepsy of Gastaut