Small volume of amniotic fluid is extracted via amniocentesis with a syringe. DNA analysis is generally used to determine if parents are carriers of the mutant gene. Prenatal diagnosis through either DNA analysis or determination of NAA in amniotic fluid (which would be increased in an affected pregnancy) can also be used when DNA analysis cannot be performed on parents. It has been observed that there is an abnormally high carrier rate in the Ashkenazi Jewish population. The risk of their offspring having<unk>  degeneration is one in four if both parents are carriers of the mutant gene.
Spongy degeneration of the central nervous system
Lesional demyelinations of the central nervous system
Inflammatory demyelinating diseases of the central nervous system
Visual pathway lesions
Neurogenic inflammation
Central nervous system fatigue
Effects of early-life exposures to anesthesia on the brain
Neurodegeneration with brain iron accumulation