<unk>  <unk>  is a type of muscular dystrophy, a group of genetic disorders that cause progressive muscle loss and weakness. In<unk> , muscles are often unable to relax after contraction. Other manifestations may include cataracts, intellectual disability and heart conduction problems. In men, there may be early balding and an inability to have children. While<unk>  can occur at any age, onset is typically in the 20s and 30s.<unk>  is caused by a genetic mutation in one of two genes. Mutation of the<unk> PK gene causes<unk>  type 1 <unk> 1). Mutation of CNBP gene causes type 2 <unk> 2).<unk>  is typically inherited from a person's parents, following an autosomal dominant inheritance pattern, and it generally worsens with each generation. A type of<unk> 1 may be apparent at birth.<unk> 2 is generally milder. Diagnosis is confirmed by genetic testing. There is no cure. Treatments may include braces or wheelchairs, pacemakers and non-invasive positive pressure ventilation. The medications mexiletine or carbamazepine can help relax muscles. Pain, if it occurs, may be treated with tricyclic antidepressants and nonsteroidal anti-inflammatory drugs (NSAIDs).<unk>  affects more than 1 in 8,000 people worldwide. It is the most common form of muscular dystrophy that begins in adulthood. It was first described in 1909, with the underlying cause of type 1 determined in 1992.
Myotonic dystrophy
Prader–Willi syndrome
Becker muscular dystrophy
Myotonia congenita
Muscular dystrophy
Ullrich congenital muscular dystrophy
Madras motor neuron disease
Infantile neuroaxonal dystrophy