T2-weighted MRI images of a 25 year-old male with<unk>  revealing dysmyelination in the deep periventricular white matter and reduced brain volume in the frontal lobe. * Dry and scaly skin similar to all other ichtyosiforms (types of ichthyosis). * Neurological problems – this can often cause mild paralysis in the legs * Mild to moderate intellectual disability. * Often associated ocular features, which include pigmentary changes in the retina. The usual presentation of crystalline maculopathy is from the age of 1-2 years onwards.
Sjögren–Larsson syndrome
Marinesco–Sjögren syndrome
Sjögren syndrome
Neuro-Behçet's disease
Anti-IgLON5 disease
Auto-brewery syndrome
CREST syndrome
Sever's disease