Concomitant use of<unk>  and moderate or potent CYP1A2 inhibitors (such as zileuton, certain antiarrhythmics (amiodarone, mexiletine, propafenone, verapamil), cimetidine, famotidine, aciclovir, ticlopidine and oral contraceptives) is contraindicated. Concomitant use of<unk>  with fluvoxamine, a potent CYP1A2 inhibitor in humans, resulted in a 33-fold increase in the<unk>  AUC (plasma drug concentration-time curve). For this reason both fluvoxamine and<unk>  should not be taken at the same time. Fluoroquinolone antibiotics such as moxifloxacin, levofloxacin, and ciprofloxacin should also be avoided due to an increased serum concentration of<unk>  when administered concomitantly.<unk>  has the potential to interact with other central nervous system depressants. Alcohol should be avoided, particularly as it can upset the stomach. The CNS-depressant effects of<unk>  and alcohol are additive. Caution with the following interactions: * antibiotics such as enoxacin, gatifloxacin, levofloxacin, lomefloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, or norfloxacin; * blood pressure medications such as clonidine, guanabenz, guanfacine (Tenex), or methyldopa; * heart rhythm medications such as amiodarone (Cordarone, Pacerone), mexiletine (Mexitil), propafenone (Rhythmol), and verapamil (Calan, Covera, Isoptin).
Tizanidine
Ibogaine
Aceclidine
Noribogaine
Esketamine
Nefopam
Lofexidine
Propofol