<unk> , sold under the brandname CroFab, is a snake antivenin, indicated for minimal or moderate North American Crotalid (Rattlesnake, Copperhead and Cottonmouth/Water moccasin) snake envenomation. CroFab is composed of several monovalent Fragment antigen-binding proteins <unk>  derived from the blood of sheep<unk> zed with one of four snake venom: Crotalus atrox (western diamondback rattlesnake), Crotalus adamanteus (Eastern diamondback rattlesnake), Crotalus scutulatus (Mojave rattlesnake), or Agkistrodon piscivorus (Cottonmouth or Water Moccasin). Each monospecific antivenin is purified from sheep serum, digested with the enzyme papain, and purified further resulting in specific<unk>  fragments. The resulting four different<unk>  preparations are mixed to formulate the final product.
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