The term<unk>  is from Greek words meaning "large cell". A<unk>  class of<unk>  is an<unk>  (defined as blood with an insufficient concentration of hemoglobin) in which the red blood cells (erythrocytes) are larger than their normal volume. The normal erythrocyte volume in humans is about 80 to 100 femtoliters (fL= 10−15 L). In metric terms the size is given in equivalent cubic micrometers (1 μm3 = 1 fL). The condition of having erythrocytes which (on average) are too large, is called macrocytosis. In contrast, in<unk> , the erythrocytes are smaller than normal. In a<unk> , the larger red cells are always associated with insufficient numbers of cells and often also insufficient hemoglobin content per cell. Both of these factors work to the opposite effect of larger cell size, to finally result in a total blood hemoglobin concentration that is less than normal (i.e.,<unk> .<unk>  is not a disease in the sense of having a single pathology but, rather, is a condition. As such, it is the class name for a set of pathologies that all produce somewhat the same red blood cell abnormality. Different pathologies result in<unk> -type<unk> s. Some of these pathologies produce slightly different sets of appearances in blood cells that are detectable from red and white cell morphology, and others are only detectable with chemical testing.
Macrocytic anemia
Lycopenemia
Plasmacytosis
Reticulocytosis
Neutrophilia
Microcytic anemia
Microhematuria
Hepatosplenomegaly