The<unk>  are diagnostic criteria for multiple sclerosis (MS). These criteria are named after neurologist W. Ian<unk>  who directed an international panel in association with the National Multiple Sclerosis Society (NMSS) of America and recommended revised diagnostic criteria for MS in April 2001. These new criteria intended to replace the Poser criteria and the older Schumacher criteria. They have undergone revisions in 2005, 2010 and 2017. They maintain the Poser requirement to demonstrate "dissemination of lesions in space and time" (DIS and DIT) but they discourage the previously used Poser terms such as "clinically definite" and "probable MS", and propose as diagnostic either "MS", "possible MS", or "not MS". The<unk>  maintained a scheme for diagnosing MS based solely on clinical grounds but also proposed for the first time that when clinical evidence is lacking, magnetic resonance imaging (MRI) findings can serve as surrogates for dissemination in space (DIS) and/or time (DIT) to diagnose MS. The criteria try to prove the existence of demyelinating lesions, by image or by their effects, showing that they occur in different areas of the nervous system (DIS) and that they accumulate over time (DIT). The<unk>  facilitate the diagnosis of MS in patients who present with their first demyelinating attack and significantly increase the sensitivity for diagnosing MS without compromising the specificity. The<unk>  for the diagnosis of multiple sclerosis were revised first in 2005 to clarify exactly what is meant by an "attack", "dissemination" and a "positive MRI", etc. Later they were revised again in 2017.<unk>  are the standard clinical case definition for MS and the 2010 version is regarded as the gold standard test for MS diagnosis.
McDonald criteria
Poser criteria
Bradford Hill criteria
Schumacher criteria
NINCDS-ADRDA Alzheimer's Criteria
Centor criteria
Ranson criteria
Coma scale