<unk> is a rare, incurable, and fatal neurodegenerative disorder that was formerly common among the Fore people of Papua New Guinea.<unk> is a form of transmissible spongiform encephalopathy (TSE) caused by the transmission of abnormally folded proteins (prions), which leads to symptoms such as tremors and loss of coordination from neurodegeneration. The term<unk> derives from the Fore word kuria or guria ("to shake"), due to the body tremors that are a classic symptom of the disease.<unk> itself means "trembling". It is also known as the "laughing sickness" due to the pathologic bursts of laughter which are a symptom of the disease. It is now widely accepted that<unk> was transmitted among members of the Fore tribe of Papua New Guinea via funerary cannibalism. Deceased family members were traditionally cooked and eaten, which was thought to help free the spirit of the dead. Women and children usually consumed the brain, the organ in which infectious prions were most concentrated, thus allowing for transmission of<unk>  The disease was therefore more prevalent among women and children. The epidemic likely started when a villager developed sporadic Creutzfeldt–Jakob disease and died. When villagers ate the brain, they contracted the disease, and it was then spread to other villagers who ate their infected brains. While the Fore people stopped consuming human meat in the early 1960s, when it was first speculated to be transmitted via endocannibalism, the disease lingered due to<unk> s long incubation period of anywhere from 10 to over 50 years. The epidemic finally declined sharply after half a century, from 200 deaths per year in 1957 to no deaths from at least 2010 onwards, with sources disagreeing on whether the last known<unk> victim died in 2005 or 2009.
Kuru 
Samu
Onyalai
Uinyeo
Higi
Hives
Kava
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