Educative measures can partially manage developmental delays, with success variable on the degree of severity. Management of epilepsy is difficult, and some pachygyria patients are drug resistant, including to combination therapies. Orthopedic monitoring is mandatory, since progressive join limitations could lead to loss of autonomous ambulation.
Fryns-Aftimos syndrome
Yunis–Varon syndrome
Helsmoortel-Van der Aa syndrome
CAMFAK syndrome
Townes–Brocks syndrome
Teunissen–Cremers syndrome
Pretzel syndrome
Cortes Lacassie syndrome