A<unk>  (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with<unk> , it is common for collagen and elastin to become injured by inflammation (ICT). Many<unk> s feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity). Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. Collagen vascular diseases can be (but are not necessarily) associated with collagen and blood vessel abnormalities that are autoimmune in nature. See also vasculitis.<unk> s can have strong or weak inheritance risks, and can also be caused by environmental factors.
Connective tissue disease
Connective tissue neoplasm
Undifferentiated connective tissue disease
Neuromuscular junction disease
Collagen disease
Cartilage tumor
Neuromuscular disease
Congenital heart defect