Neonates with<unk> s, especially those with SP-B disorder, only have lung transplantation as one possible choice of treatment. Children with lung transplant due to<unk>  perform on similar level to those with transplant for due to other reasons. Some less severe cases of ABCA3 dysfunctions manifest in late childhood or adult hood are due to missense mutations that result in semi-sufficient levels of active<unk> , while SP-C clinical presentation varies greatly depending on level of penetration of the mutated alleles.
Surfactant metabolism dysfunction
Congenital pulmonary airway malformation
Hypoplastic right heart syndrome
Humoral immune deficiency
Vocal cord dysfunction
Anomalous pulmonary venous connection
Hypoplastic left heart syndrome
Upper airway resistance syndrome