Affected individuals may present with hypoglycaemia during the neonatal period, or with growth retardation during childhood (those diagnosed in the neonatal period appear to be affected by a particularly severe form of the disorder).<unk>  is a common cause of congenital hypopituitarism, and causes a permanent growth hormone deficit. Some<unk> -affected individuals may also present with adrenal hypoplasia (5-29%), diabetes insipidus (5-29%), primary amenorrhea (5-29%), hypothyroidism (30-79%), failure to thrive (80-99%), septooptic dysplasia (5-29%), and Fanconi anaemia.<unk>  may be isolated, or, commonly, present with extra-pituitary malformations.<unk>  features in neonates (may) include: * hypoglycaemia (30-79%) * (prolonged) jaundice * micropenis (30-79%) * cryptorchidism (5-29%) * delayed intellectual development * death in infancy (5-29%) * congenital abnormalities<unk>  features in later childhood (may) include: * short stature (80-99%) * seizures (5-29%) * hypotension * delayed intellectual development * delayed puberty (30-79%)<unk>  is associated with a higher frequency of breech presentation, Caeserian section, and/or low Apgar score, though these are likely consequences rather than causes.
Pituitary stalk interruption syndrome
Kallmann syndrome
Persistent adrenarche syndrome
Lipoid congenital adrenal hyperplasia
Hypopituitarism
Karak syndrome
Young's syndrome
Waldmann disease