The Influenza virus has both hemagglutinin and neuraminidase spikes that are being used as antigen binding sites in the search for a<unk>  vaccine. A<unk>  is a<unk>  vaccine that is effective against all influenza strains regardless of the virus sub type, antigenic drift or antigenic shift. Hence it should not require modification from year to year. As of 2021 no<unk>  had been approved for general use, several were in development, and one was in clinical trial.
Universal flu vaccine
Rabies vaccine
Hantavirus vaccine
Dengue vaccine
Measles vaccine
Yellow fever vaccine
Ebola vaccine
Malaria vaccine