Symptoms and symptom onset vary; some individuals are diagnosed in childhood, others in adulthood, some report minor problems, whilst others experience severe discomfort and disability. In many cases, symptoms are mild enough to go unnoticed. The time period between episodes is known to vary between individuals.<unk>  has not been found to alter the lifespan, although in some cases a decline in quality of life is noticed. Some sufferers (10–15%) report various pains growing in severity with progression of the disease. The nerves most commonly affected are the peroneal nerve at the fibular head (leg and feet), the ulnar nerve at the elbow (arm) and the median nerve at the wrist (palm, thumbs and fingers), but any peripheral nerve can be affected. Among the signs/symptoms are the following (different symptoms are caused by different nerves, such as the foot drop caused by the peroneal nerve):
Hereditary neuropathy with liability to pressure palsy
Hereditary neuralgic amyotrophy
Hereditary sensory and autonomic neuropathy
Hereditary motor and sensory neuropathy
Lethal arthrogryposis with anterior horn cell disease
Distal hereditary motor neuropathy type V
Chronic inflammatory demyelinating polyneuropathy
Hereditary sensory and autonomic neuropathy type I