Mechanism of action<unk>  binds to and potentiates antithrombin (a circulating anticoagulant) to form a complex that irreversibly inactivates clotting factor Xa. It has less activity against factor IIa (thrombin) compared to unfractionated heparin (UFH) due to its low molecular weight. Pharmacokinetics Absorption: Bioavailability (subcutaneous injection) ~ 100% Distribution: Volume of distribution (anti-Factor Xa activity) = 4.3 liters Metabolism:<unk>  is metabolized in the liver into low molecular weight species by either or both desulfation and depolymerization. Elimination: A single dose of a subcutaneous injection of<unk>  has an elimination half-life of 4.5 hours. Approximately 10–40% of the active and inactive fragments from a single dose are excreted by the kidneys. Dose adjustments based on kidney function are necessary in persons with reduced kidney function. Drug class<unk>  belongs to the class of drugs known as low molecular weight heparins. Other drugs in this class include dalteparin, fondaparinux and tinzaparin.
Enoxaparin sodium
Apixaban
Palladin
Dabigatran
Cilostazol
Ticlopidine
Rivaroxaban
Pitavastatin