The absolute bioavailability of<unk>  is low. It is reported to achieve therapeutic plasma concentrations between 49 and 183 nM. The drug is approximately 73% protein-bound across a plasma range of 7 to 226 ng/mL (28–892 nM). The metabolism of<unk>  is hepatic, by N-demethylation and via other routes. Its terminal half-life is 3 to 8 hours, while that of its active metabolite, desmethylnefopam, is 10 to 15 hours. It is eliminated mostly in urine, and to a lesser extent in feces.
Nefopam
Setiptiline
Lofexidine
Ivabradine
Fenoldopam
Verapamil
Alvimopan
Iofetamine 