<unk>  <unk> , often shortened to<unk> ox, is a neurotoxic protein produced by the bacterium Clostridium<unk> ulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The<unk>  causes the disease<unk> ulism. The<unk>  is also used commercially for medical and cosmetic purposes. The seven main types of<unk>  are named types A to G (A, B, C1, C2, D, E, F and G). New types are occasionally found. Types A and B are capable of causing disease in humans, and are also used commercially and medically. Types C–G are less common; types E and F can cause disease in humans, while the other types cause disease in other animals.<unk>  types A and B are used in medicine to treat various muscle spasms.<unk> s are the most potent<unk> s known. Intoxication can occur naturally as a result of either wound or intestinal infection or by ingesting formed<unk>  in food. The estimated human lethal dose of type A<unk>  is 1.3–2.1 ng/kg intravenously or intramuscularly, 10–13 ng/kg when inhaled, or 1000 ng/kg when taken by mouth. Commercial forms are marketed under the brand names<unk> ox (onabotulinumtoxinA), Dysport/Azzalure (abobotulinumtoxinA), Xeomin/Bocouture (incobotulinumtoxinA), and Jeuveau (prabotulinumtoxinA).
Botulinum toxin
Bungarotoxin
Brevetoxin
Latrotoxin
Kurtoxin
Charybdotoxin
Tetrodotoxin
Α-Bungarotoxin