<unk>  is an extremely rare overgrowth syndrome with complex vascular anomalies.<unk>  affects people with various symptoms, ranging from mild fatty soft-tissue tumors to vascular malformations encompassing the spine or internal organs.<unk>  is closely linked to other overgrowth disorders like proteus syndrome, Klippel–Trénaunay syndrome, Sturge–Weber syndrome, and hemihypertrophy, to name a few. It can also cause fat to move to the back, and many cases undescended testicles.<unk> ' is an acronym for: * C is for congenital. * L is for lipomatous, which means pertaining to or resembling a benign tumor made up of mature fat cells. Most<unk>  patients present with a soft fatty mass at birth, often visible on one or both sides of the back, legs and/or abdomen. * O is for overgrowth, because there is an abnormal increase in the size of the body or a body part that is often noted at birth. Patients with<unk>  may have affected areas of their bodies that grow faster than in other people. Overgrowth of extremities (usually arms or legs) is seen, with large wide hands or feet, large fingers or toes, wide space between fingers, and asymmetry of body parts. * V is for vascular malformations, which are blood vessel abnormalies. Patients with<unk>  have different venous, capillary, and lymphatic channels - typically capillary, venous and lymphatic malformations are known as "slow flow" lesions. Some patients with<unk>  have combined lesions (which are fast flow) and some have aggressive vascular malformation known as arteriovenous malformations (AVM). The effect of a vascular malformation varies per patient based on the type, size, and location of the malformation, and symptoms can vary. * E is for Epidermal naevi, which are sharply-circumscribed chronic lesions of the skin, and benign. These are often flesh-colored, raised or warty. * S is for Spinal/Skeletal Anomalies or scoliosis. Some patients with<unk>  have tethered spinal cord, vascular malformations in or around their spines, and other spinal differences. High-flow aggressive spinal lesions (like AVM) can cause serious neurological deficits/paralysis. The syndrome was first recognised by Saap and colleagues who recognised the spectrum of symptoms from a set of seven patients. In this initial description the syndrome is named<unk> . It is believed that the first description of a case of<unk>  was written by Hermann Friedberg, a German physician, in 1867. __TOC__
CLOVES syndrome
RAPADILINO syndrome
Fryns-Aftimos syndrome
RIDDLE syndrome
CAMFAK syndrome
Crigler–Najjar syndrome
GRACILE syndrome
Helsmoortel-Van der Aa syndrome