<unk>  is a centrally acting muscle relaxant.<unk>  is a 5-HT2 receptor antagonist; it relieves muscle spasm through action on the central nervous system at the brain stem, rather than targeting the peripheral nervous system or muscles themselves. Pharmacodynamics<unk>  (and metabolite) Site CBP NCBP Action Ref 5-HT1A 5.3 3.2 Agonist 5-HT2A 5.2 13 Antagonist 5-HT2B 100 ??? Antagonist 5-HT2C 5.2 43 Antagonist α1A 5.6 34 ND α2A 4.3 6.4 Antagonist α2B 21 150 ND α2C 21 48 ND H1 1.3 5.6 ND M1 7.9 30 ND Values are Ki (nM), unless otherwise noted. The smaller the value, the more strongly the drug binds to the site. Pharmacokinetics<unk>  has an oral bioavailability of about 55% and approximately 93% is bound to proteins in plasma. The half-life of the drug is 18 hours and it has a plasma clearance of 0.7 litres per minute.
Cyclobenzaprine
Bethanechol
Dihydroergotamine
Glycopyrronium bromide
Avacopan
Terbutaline
Clofoctol
Pilocarpine