<unk>  is a major risk factor for most common neurodegenerative diseases, including mild cognitive impairment, dementias including Alzheimer's disease, cerebrovascular disease, Parkinson's disease, and Lou Gehrig's disease. While much research has focused on diseases of<unk> , there are few informative studies on the molecular biology of the<unk>  (usually spelled<unk>  in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research suggests that the<unk>  process is associated with several structural, chemical, and functional changes in the<unk>  as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy<unk> .
Aging brain
Wernicke encephalopathy
Lewy body dementias
White dot syndromes
Hypertensive leukoencephalopathy
Microinfarct
Vein of Galen aneurysmal malformations
Muscle–eye–brain disease