First-line therapy Over-the-counter salicylic acid Second-line therapy Prescribed 60% salicylic acid, intralesional immunotherapy Third-line therapy Fluorouracil cream, cryotherapy, laser therapy Fourth-line therapy Bleomycin injection, surgical excision Cryotherapy being applied to a<unk>  with a cotton swab A number of treatments have been found to be effective. A 2012 review of different treatments for skin<unk> s in otherwise healthy people concluded modest benefit from salicylic acid, and cryotherapy appears similar to salicylic acid. Medications Salicylic acid, the treatment of<unk> s by keratolysis, involves the peeling away of dead surface skin cells with keratolytic chemicals such as salicylic acid or trichloroacetic acid. These are available in over-the-counter products, or in higher concentrations, may need to be prescribed by a physician. A 12-week daily treatment with salicylic acid has been shown to lead to a complete clearance of<unk> s in 10–15% of the cases. Formic acid, topical, is a common treatment for<unk> s, which works by being applied over a period of time, causing the body to reject the<unk> . Fluorouracil cream, a chemotherapy agent sometimes used to treat skin cancer, can be used on particularly resistant<unk> s, by blocking viral DNA and RNA production and repair. Bleomycin, a more potent chemotherapy drug, can be injected into deep<unk> s, destroying the viral DNA or RNA. Bleomycin is notably not US FDA approved for this purpose. Possible side effects include necrosis of the digits, nail loss, and Raynaud syndrome. The usual treatment is one or two injections. Immunotherapy, as intralesional injection of antigens (mumps, candida or trichophytin antigens USP), is a<unk>  treatment that may trigger a host immune response to the<unk>  virus, resulting in<unk>  resolution. It is now recommended as a second-line therapy. Surgery A 7 mm<unk>  surgically removed from the sole of a person's foot after other treatments failed Liquid nitrogen and similar cryosurgery methods are common surgical treatments, which act by freezing the external cell structure of the<unk> s, destroying the live tissue. Electrodesiccation and surgical excision may produce scarring. Laser surgery is generally a last resort treatment, as it is expensive and painful, but may be necessary for large, hard-to-cure<unk> s. Cauterization may be effective as a prolonged treatment. As a short-term treatment, cauterization of the base with anesthetic can be effective, but this method risks scarring or keloids. Subsequent surgical removal, if necessary, also risks keloids and/or recurrence in the operative scar.
Plantar wart
Callus
Veinoplus
Molluscum contagiosum
Broken toe
Squamous cell carcinoma
Freckle
Broken finger