<unk>  is a rare genetic disorder of the immune system. This disorder is caused by a mutation in the gene<unk> .<unk>  stands for “lipopolysaccharide (LPS)-responsive and beige-like anchor protein”. This condition is characterized by autoimmunity, lymphoproliferation, and immune deficiency. It was first described by Gabriela Lopez-Herrera from University College London in 2012. Investigators in the laboratory of Dr. Michael Lenardo at National Institute of Allergy and Infectious Diseases, the National Institutes of Health and Dr. Michael Jordan at Cincinnati Children’s Hospital Medical Center later described this condition and therapy in 2015.
LRBA deficiency
NGLY1 deficiency
Adenosine deaminase 2 deficiency
WNT4 deficiency
Janus kinase 3 deficiency
PMM2 deficiency
Adenosine deaminase deficiency
GATA2 deficiency