__NOTOC__<unk> , or XPD is a protein involved in transcription-coupled nucleotide excision repair. The XPD<unk>  gene encodes for a 2.3-kb mRNA containing 22 exons and 21 introns. The XPD protein contains 760 amino acids and is a polypeptide with a size of 87kDa. Defects in this gene can result in three different disorders: the cancer-prone syndrome xeroderma pigmentosum complementation group D, photosensitive trichothiodystrophy, and Cockayne syndrome. Just like XPB, XPD is a part of human transcriptional initiation factor TFIIH and has ATP-dependent helicase activity. It belongs to the RAD3/XPD subfamily of helicases. XPD is essential for the viability of cells. Deletion of XPD in mice is lethal for developing embryos.
ERCC2
CoWIN
FCER1
WRAP53
KRAS
INK4
BRCA1
TFM-4AS-1