Therapy involves both preventive measures and treatment of specific bleeding episodes. * Dental hygiene lessens gingival bleeding * Avoidance of antiplatelet agents such as aspirin and other anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, and anticoagulants * Iron or folate supplementation may be necessary if excessive or prolonged bleeding has caused anemia * Hepatitis B vaccine * Antifibrinolytic drugs such as tranexamic acid or ε-aminocaproic acid (Amicar) * Desmopressin (DDAVP) does not normalize the bleeding time in<unk>  but anecdotally improves hemostasis * Hormonal contraceptives to control excessive menstrual bleeding * Topical agents such as gelfoam, fibrin sealants, polyethylene glycol polymers, custom dental splints * Platelet transfusions (only if bleeding is severe; risk of platelet alloimmunization) * Recombinant factor VIIa, AryoSeven or NovoSeven FDA approved this drug for the treatment of the disease in July 2014. * Hematopoietic stem cell transplantation (HSCT) for severe recurrent hemorrhages
Glanzmann's thrombasthenia
Harris platelet syndrome
Quebec platelet disorder
Gray platelet syndrome
Sticky platelet syndrome
Bernard–Soulier syndrome
Von Willebrand disease
Acquired haemophilia