Infection If a<unk>  becomes more painful this is a good indication that it is infected. A lack of pain however does not mean that it is not infected. Other methods of determination are less effective. Classification The vast majority of<unk> s can be classified into three categories: venous ulcers, diabetic, and pressure ulcers. A small number of<unk> s that do not fall into these categories may be due to causes such as radiation poisoning or ischemia. Venous and arterial ulcers Venous ulcers, which usually occur in the legs, account for about 70% to 90% of<unk> s and mostly affect the elderly. They are thought to be due to venous hypertension caused by improper function of valves that exist in the veins to prevent blood from flowing backward. Ischemia results from the dysfunction and, combined with reperfusion injury, causes the tissue damage that leads to the<unk> s. Diabetic ulcers Another major cause of<unk> s, diabetes, is increasing in prevalence. Diabetics have a 15% higher risk for amputation than the general population due to chronic ulcers. Diabetes causes neuropathy, which inhibits nociception and the perception of pain. Thus patients may not initially notice small<unk> s to legs and feet, and may therefore fail to prevent infection or repeated injury. Further, diabetes causes immune compromise and damage to small blood vessels, preventing adequate oxygenation of tissue, which can cause<unk> s. Pressure also plays a role in the formation of diabetic ulcers. Pressure ulcers Another leading type of<unk> s is pressure ulcers, which usually occur in people with conditions such as paralysis that inhibit movement of body parts that are commonly subjected to pressure such as the heels, shoulder blades, and sacrum. Pressure ulcers are caused by ischemia that occurs when pressure on the tissue is greater than the pressure in capillaries, and thus restricts blood flow into the area. Muscle tissue, which needs more oxygen and nutrients than skin does, shows the worst effects from prolonged pressure. As in other chronic ulcers, reperfusion injury damages tissue.
Chronic wound
Burn scar contracture
Wound contracture
Implant failure
Cancer cluster
Postoperative wounds
Stab wound
Chronic limb threatening ischemia