<unk> , also known as Swyer syndrome, is a type of hypogonadism in a person whose karyotype is 46,XY. Though they typically have normal female external genitalia, the person has functionless gonads, fibrous tissue termed "streak gonads", and if left untreated, will not experience puberty. Such gonads are typically surgically removed (as they have a significant risk of developing cancer). The typical medical treatment is hormone replacement therapy. The syndrome was named after Gerald Swyer, an endocrinologist based in London.
XY gonadal dysgenesis
XX gonadal dysgenesis
Thyroid dysgenesis
Complete androgen insensitivity syndrome
Mild androgen insensitivity syndrome
Gonadotropin-releasing hormone insensitivity
Gonadal dysgenesis
Müllerian agenesis