Neurotoxic<unk> caused by botulinum toxin: a 14-year-old botulism patient with bilateral total ophthalmoplegia with<unk> (left image) and dilated, fixed pupils (right image). The teenager was fully conscious Phineas Gage displayed<unk> after a large iron rod entered his left cheek, passed behind his left eye, and exited at the top of his head<unk> occurs due to dysfunction of the muscles that raise the eyelid or their nerve supply (oculomotor nerve for levator palpebrae superioris and sympathetic nerves for superior tarsal muscle). It can affect one eye or both eyes and is more common in the elderly, as muscles in the eyelids may begin to deteriorate. One can, however, be born with<unk>  This is due to improper development of the infant's levator muscle while still in the mother's womb. Congenital<unk> is hereditary in three main forms. Causes of congenital<unk> remain unknown.<unk> may be caused by damage to the muscle which raises the eyelid, damage to the superior cervical sympathetic ganglion or damage to the nerve (3rd cranial nerve (oculomotor nerve)) which controls this muscle. Such damage could be a sign or symptom of an underlying disease such as diabetes mellitus, a brain tumor, a pancoast tumor (apex of lung) and diseases which may cause weakness in muscles or nerve damage, such as myasthenia gravis or oculopharyngeal muscular dystrophy. Exposure to the toxins in some snake venoms, such as that of the black mamba, may also cause this effect.<unk> can be caused by the aponeurosis of the levator muscle, nerve abnormalities, trauma, inflammation or lesions of the lid or orbit. Dysfunctions of the levators may occur as a result of autoimmune antibodies attacking and eliminating the neurotransmitter.<unk> may be due to a myogenic, neurogenic, aponeurotic, mechanical or traumatic cause, and it usually occurs isolated, but may be associated with various other conditions, like immunological, degenerative, or hereditary disorders, tumors or infections. Acquired<unk> is most commonly caused by aponeurotic<unk>  This can occur as a result of senescence, dehiscence or disinsertion of the levator aponeurosis. Moreover, chronic inflammation or intraocular surgery can lead to the same effect. Also, wearing contact lenses for long periods of time is thought to have a certain impact on the development of this condition. Congenital neurogenic<unk> is believed to be caused by Horner's syndrome. In this case, a mild<unk> may be associated with ipsilateral<unk>  iris and areola hypopigmentation and anhidrosis due to paresis of the superior tarsal muscle. Acquired Horner syndrome may result after trauma, neoplastic insult, or even vascular disease.<unk> due to trauma can ensue after an eyelid laceration with transection of the upper eyelid elevators or disruption of the neural input. Other causes of<unk> include eyelid neoplasms, neurofibromas or the cicatrization after inflammation or surgery. Mild<unk> may occur with aging. A drooping eyelid can be one of the first signals of a third nerve palsy due to a cerebral aneurysm, that otherwise is asymptomatic and referred to as an oculomotor nerve palsy. Drugs Use of high doses of opioid drugs such as morphine, oxycodone, heroin, or hydrocodone can cause<unk>  Pregabalin, an anticonvulsant drug, has also been known to cause mild<unk>
Ptosis 
Photophobia
Mydriasis
Cynanthropy
Pityriasis
Facial toning
Athetosis
Iontophoresis