The side effects of<unk>  have been said to be similar to those of other tertiary amine TCAs, with a preponderance of anticholinergic and sedative effects. However,<unk>  has also been said to be associated with a different side effect profile compared to other TCAs and in general with fewer side effects, chiefly due to its lack of norepinephrine reuptake inhibition and relatively lower anticholinergic effects (although it is still a potent anticholinergic). Somnolence is the most common side effect of the drug. Dry mouth is the most common anticholinergic side effect, but others like constipation, urinary retention, and blurred vision are also present. It is described as being associated with minimal or no orthostatic hypotension, at least in comparison to clomipramine, in spite of its potent and comparable activity as an alpha-1 blocker. However, it has also been said to have a rate of orthostatic hypotension similar to that of other TCAs.<unk>  is said to be less epileptogenic than other TCAs, although seizures have still been reported in association with it. It is also less cardiotoxic than other TCAs and cardiotoxicity is said to be minimal, with a "very favorable profile". List of side effects Common adverse effects include: * Sedation — especially common with<unk>  compared to the other TCAs * Anticholinergic effects including: :- dry mouth :- blurred vision :- mydriasis :- decreased lacrimation :- constipation :- urinary hesitancy or retention :- reduced GI motility :- tachycardia (high heart rate) :- anticholinergic delirium (particularly in the elderly and in Parkinson's disease) * Weight gain * Orthostatic hypotension * Sexual dysfunction including impotence, loss of libido and other sexual adverse effects * Tremor * Dizziness * Sweating * Anxiety * Insomnia * Agitation * Rash Adverse effects with an unknown incidence includes: * Confusion * Nausea * Vomiting * Extrapyramidal side effects (e.g. parkinsonism, dystonia, etc.) * Tinnitus * Paraesthesia * ECG changes * Increased liver function tests Rare adverse effects include: * Seizures * Syndrome of inappropriate secretion of antidiuretic hormone * Blood dyscrasias including: * Agranulocytosis * Thrombocytopenia * Eosinophilia * Leukopenia * Myocardial infarction * Heart block * QTc interval prolongation * Sudden cardiac death * Depression worsening * Suicidal ideation
Trimipramine
Carpipramine
Clomipramine
Desipramine
Imipramine
Sertraline
Citalopram
Chlorpromazine