Spread from the skin is unusual, and the prognosis is excellent with a 5-year survival of over 97%. The International Extranodal Lymphoma Study Group identified elevated LDH, more than two skin lesions, and nodular lesions as three prognostic factors, that are used to assess a cutaneous lymphoma international prognostic index (CLIPI), which is prognostic of disease-free status.
Primary cutaneous follicle center lymphoma
Primary cutaneous immunocytoma
Cutaneous T cell lymphoma
Primary cutaneous marginal zone lymphoma
Cutaneous B-cell lymphoma
Generalized eruptive histiocytoma
Subcutaneous T-cell lymphoma
Cutaneous lymphoma