The degeneration of white matter, which shows the degeneration of myelin, can be seen in a basic MRI and used to diagnose<unk> es of all types. T-1 and T-2 weighted FLAIR images are the most useful. FLAIR stands for fluid-attenuated inversion recovery. Electrophysiological and other kinds of laboratory testing can also be done. In particular, nerve conduction velocity is looked at to distinguish between<unk>  and other demyelinating diseases, as well as to distinguish between individual<unk> es. For example, individuals with X-ALD have normal conduction velocities, while those with Krabbe disease or metachromatic<unk>  have abnormalities in their conduction velocities. Next generation multigene sequencing panels for undifferentiated<unk>  can now be offered for rapid molecular diagnosis after appropriate genetic counselling. Types Specific types of<unk> es include the following with their respective ICD-10 codes when available: * (E71.3) Adrenomyeloneuropathy * (E75.2) Alexander disease * (E75.5) Cerebrotendineous xanthomatosis * Hereditary CNS demyelinating disease * (E75.2) Krabbe disease * (E75.2) Metachromatic<unk>  * (E75.2) Pelizaeus–Merzbacher disease * (E75.2) Canavan disease * (E75.2) Hypomyelinating<unk>  type 7 (4H syndrome) * (G93.49) Leukoencephalopathy with vanishing white matter * (E71.3) Adrenoleukodystrophy * (G60.1) Refsum disease
Leukodystrophy
Dysthanasia
Huntington's disease-like syndrome
Metachromatic leukodystrophy
Post-encephalitic parkinsonism
Benign hereditary chorea
Acorea, microphthalmia and cataract syndrome
Non-progressive congenital ataxia