<unk>  <unk>  is a rare disease in which amoebae of the genus<unk>  invade the clear portion of the front (cornea) of the eye. It affects roughly 100 people in the United States each year.<unk>  are protozoa found nearly ubiquitously in soil and water and can cause infections of the skin, eyes, and central nervous system. Infection of the cornea by<unk>  is difficult to treat with conventional medications, and<unk>  may cause permanent visual impairment or blindness, due to damage to the cornea or through damage to other structures important to vision. Recently,<unk>  has been recognized as an orphan disease and a funded project, orphan diseases<unk>  (ODAK), has tested the effects of a diverse range drugs and biocides on<unk> .
Acanthamoeba keratitis
Herpes simplex keratitis
Fungal keratitis
Nummular keratitis
Neurotrophic keratitis
Diffuse lamellar keratitis
Peripheral ulcerative keratitis
Interstitial keratitis