Nonetheless, a few speculations for the causes have been made. During ovulation, the follicle ruptures resulting in epithelial cell damage. In order to heal the tissue and replace the damage, the cells undergoes cell division. Each time the cell divides, there is a possibility for mutations to occur and the chance of<unk> formation increases. The<unk> is caused when the germ cells in the ovaries begin divide uncontrollably and become malignant which are characterized with their less organized nuclei and unclearly defined border. Another potential etiology is the dysfunctioning of the<unk> suppressor gene, TRC8/RNF139, or even karyotypic abnormalities after close molecular examination. OGCT has its roots in embryonic development where the primordial germ cells (PGCs) are isolated in early stages and have the ability to alter the genome as well as the transcriptome. OGCTs can be attributed to the internal mechanism of PGCs and their transforming characteristics.
Ovarian germ cell tumors
Ovarian fibroma
Ovarian mucinous tumor
Ovarian serous cystadenoma
Germ cell tumor
Gonadoblastoma
Mixed Müllerian tumor
Follicular cyst of ovary