Acute renal failure occurs in 55–70% of people with STEC-HUS, although up to 70–85% recover renal function. Patients with aHUS generally have poor outcomes, with up to 50% progressing to ESRD or irreversible brain damage; as many as 25% die during the acute phase. However, with aggressive treatment, more than 90% of patients survive the acute phase of HUS, and only about 9% may develop ESRD. Roughly one-third of persons with HUS have abnormal kidney function many years later, and a few require long-term dialysis. Another 8% of persons with HUS have other lifelong complications, such as high blood pressure, seizures, blindness, paralysis, and the effects of having part of their colon removed. The overall mortality rate from HUS is 5–15%. Children and the elderly have a worse prognosis.
Hemolytic–uremic syndrome
Disseminated intravascular coagulation
Atypical hemolytic uremic syndrome
Thrombotic thrombocytopenic purpura
Hantavirus hemorrhagic fever with renal syndrome
Artificial heart valve
SAHA syndrome
Severe fever with thrombocytopenia syndrome