<unk>  is a fungal infection that presents with painless skin lesions of face and neck, fever, anaemia, large lymph glands and liver. It is caused by the fungusTalaromyces marneffei, which is found in soil and decomposing organic matter. The infection is thought to be acquired by breathing in the fungus from the environment, however, the environmental source of the organism is not known. It typically occurs in people who are already sick and unable to fight infection such as HIV/AIDS, cancer, organ transplant, long-term steroid use, old age, malnutrition or autoimmune disease. It generally does not affect healthy people and does not spread from person to person. Diagnosis is usually made by identification of the fungus from clinical specimens, either by microscopy or culture. Biopsies of skin lesions, lymph nodes, and bone marrow demonstrate the presence of organisms on histopathology. Medical imaging may reveal shadows in the lungs. The disease can look similar to tuberculosis and histoplasmosis.<unk>  may be prevented in people at high risk, using the antifungal medication itraconazole, and is treatable with amphotericin B followed by itraconazole or voriconazole. The disease is fatal in 75% of those not given treatment.<unk>  is endemic exclusively to southeast Asia (including southern China and eastern India), and particularly in young farmers. The exact number of people in the world affected is not known. Men are affected more than women. The first natural human case of<unk>  was reported in 1973 in an American minister with Hodgkin's disease who lived in Southeast Asia.
Talaromycosis
Histoplasmosis
Chromoblastomycosis
Tuberculosis
Conidiobolomycosis
Botryomycosis
Basidiobolomycosis
Phycomycosis