<unk>  has been evaluated for potential drug interactions with the following medications and showed no significant effects: omeprazole, theophylline, dextromethorphan, and midazolam, digoxin and warfarin. There were no clinically meaningful effects when<unk>  was coadministered with any of these drugs. A drug interaction study showed that there were no clinically meaningful effects or an increase in adverse events when<unk>  and the SSRI Prozac (fluoxetine) were coadministered. When coadministered with<unk> , fluvoxamine (strong CYP1A2 inhibitor) increased AUC approximately 190-fold, and the Cmax increased approximately 70-fold, compared to<unk>  administered alone.<unk>  and fluvoxamine should not be coadministered.<unk>  should be administered with caution in patients taking other CYP1A2 inhibitors, strong CYP3A4 inhibitors such as ketoconazole, and strong CYP2C9 inhibitors such as fluconazole. Efficacy may be reduced when<unk>  is used in combination with potent CYP enzyme inducers such as rifampin, since<unk>  concentrations may be decreased.
Ramelteon
Enarodustat
Elixir
Miglustat
Snoezelen
Ecallantide
Patisiran
Zileuton