<unk>  <unk>  is a set of symptoms that can occur following a reduction in<unk>  use after a period of excessive use. Symptoms typically include anxiety, shakiness, sweating, vomiting, fast heart rate, and a mild fever. More severe symptoms may include seizures, hallucinations, and delirium tremens (DTs). Symptoms typically begin around six hours following the last drink, are worst at 24 to 72 hours, and improve by seven days.<unk>  withdrawal may occur in those who are<unk>  dependent. This may occur following a planned or unplanned decrease in<unk>  intake. The underlying mechanism involves a decreased responsiveness of GABA receptors in the brain. The withdrawal process is typically followed using the Clinical Institute Withdrawal Assessment for<unk>  scale (CIWA-Ar). The typical treatment of<unk>  withdrawal is with benzodiazepines such as chlordiazepoxide or diazepam. Often the amounts given are based on a person's symptoms. Thiamine is recommended routinely. Electrolyte problems and low blood sugar should also be treated. Early treatment improves outcomes. In the Western world about 15% of people have problems with<unk>  use disorder at some point in time. About half of people with<unk>  use disorder will develop withdrawal symptoms upon reducing their use, with four percent developing severe symptoms. Among those with severe symptoms up to 15% die. Symptoms of<unk>  withdrawal have been described at least as early as 400 BC by Hippocrates. It is not believed to have become a widespread problem until the 1700s.
Alcohol withdrawal syndrome
Epilepsy
Benzodiazepine withdrawal syndrome
Drug withdrawal
Post-acute-withdrawal syndrome
Nicotine withdrawal
Opioid withdrawal
Cocaine intoxication