<unk>  (DCMO) is a subset of capillary malformations (CM) associated with hypertrophy, i.e. increased size of body structures. CM can be considered an umbrella term for various vascular anomalies caused by increased diameter or number of capillary blood vessels. It is commonly referred to as “port-wine stain”, and is thought to affect approximately 0.5% of the population. Typically capillaries in the papillary dermis are involved, and this gives rise to pink or violaceous colored lesions. Majority of DCMO lesions are diffuse, reticulated pale-colored stains. DCMO is a unique entity from previously described vascular syndromes including: Klippel-Trenaunay Syndrome, macrocephaly-capillary malformation syndrome , cutis marmorata telangiectatica congenita, CLOVES syndrome and Proteus Syndrome. Careful evaluation must be made to rule out these vascular-complex syndromes from the differential diagnosis, as DCMO is considered a more common and benign condition.
Diffuse capillary malformation with overgrowth
Hyperkeratotic cutaneous capillary-venous malformation
Benign neonatal hemangiomatosis
Arteriovenous malformation
Diffuse neonatal hemangiomatosis
Cavernous venous malformation
Fibrillary astrocytoma
Infantile hemangiopericytoma