<unk>  <unk>  is a subtype of the<unk>  soft tissue cancer family whose lineage is from mesenchymal cells and are related to skeletal muscle cells.<unk>  tumors resemble the<unk>  tissue in the lungs. Tumor location varies from patient to patient, but is commonly found in the head and neck region, male and female urogenital tracts, the torso, and extremities. Two fusion proteins can be associated with<unk> , but are not necessary, PAX3-FKHR (now known as FOXO1). and PAX7-FKHR. In children and adolescents<unk>  accounts for about 1 percent of all malignancies, has an incidence rate of 1 per million, and most cases occur sporadically with no genetic predisposition. PAX3-FOXO1 is now known to drive cancer-promoting gene expression programs through creation of distant genetic elements called super enhancers.
Alveolar rhabdomyosarcoma
Sclerosing rhabdomyosarcoma
Spindle cell rhabdomyosarcoma
Neurofibroma
Lipoblastoma
Enchondroma
Nesidioblastoma
Esthesioneuroblastoma