TBS patients may have the following symptoms: * Abnormalities of the external ears (unusually large or small, unusually shaped, sometimes with sensorineural hearing loss or deafness due to lesions or dysfunctions of part of the internal ear or its nerve tracts and centers or conductive hearing loss from the external or middle ear), dysplastic ears, lop ear (over-folded ear helix), preauricular tags or pits (a rudimentary tag of ear tissue typically located just in front of the ear). * Anorectal malformations, including imperforate anus/absence of an anal opening, rectovaginal fistula, anal stenosis, unusually placed anus. * Kidney abnormalities, sometimes leading to impaired kidney function or kidney failure, including hypoplastic kidneys (underdeveloped), multicystic kidneys, dysplastic kidneys. * Heart abnormalities, including tetralogy of fallot and defects of the ventricular septum. * Hand and foot abnormalities, such as hypoplastic thumbs, fingerlike thumbs, syndactyly (webbed fingers/toes), fusion of the wrist bones, overlapping foot and/or toe bones. Learning difficulties have been reported in some children with TBS. For others, intelligence is within the normal range. These abnormalities, which are present prenatally, can range from minor to severe, and as with similar disorders, most individuals with this condition have some, but not all, of these traits.
Townes–Brocks syndrome
Fryns-Aftimos syndrome
Witteveen–Kolk syndrome
Lujan–Fryns syndrome
Teunissen–Cremers syndrome
Morgagni Stewart Morel syndrome
Yunis–Varon syndrome
Grisel's syndrome