Patients with severe forms of MJD have a life expectancy of approximately 35 years. Those with mild forms have a normal life expectancy. The cause of death of those who die early is often aspiration pneumonia.<ref name="Machado-Joseph Disease
Machado–Joseph disease
Darier's disease
Caroli disease
Borna disease
Lev's disease
Tornwaldt's disease
Marchiafava–Bignami disease
Bright's disease