People who are diagnosed with sporadic<unk>  often have an increased mortality rate compared to those with MEN1, as the latter group will go to the doctor for periodic visits. People whose tumor have metastasized cannot easily be treated as the tumor is resistant to chemotherapy. The only curative therapy for<unk>  is surgery, and even this is not always successful. Heightened glucagon secretion can be treated with the administration of octreotide, a somatostatin analog, which inhibits the release of glucagon. Doxorubicin and streptozotocin have also been used successfully to selectively damage alpha cells of the pancreatic islets. These do not destroy the tumor, but help to minimize progression of symptoms.
Glucagonoma
Insulinoma
Somatostatinoma
Metastatic insulinoma
VIPoma
Idiopathic hypoglycemia
Hibernoma
Gastrinoma