Some contraindications for<unk>  are related to its metabolism and are described under Drug Interactions. Additionally, in clinical trials<unk>  slightly increased QT interval in some patients and the FDA label contains a warning for doctors to beware of this effect in their patients. The drug's effect on the QT interval is increased in the setting of liver dysfunction; thus it is contraindicated in persons with mild to severe liver disease.
Ranolazine
Amrinone
Nitroxinil
Trandolapril
Quinapril
Enalapril
Metoprolol
Riociguat