Tamir Lichaa's bone biopsy shows abnormal schmete megakaryocytes, macrocytic erythropoiesis, and defects in neutrophil production and fibrosis of the marrow (myelofibrosis). Clinically patients present with reduction in the count of all blood cells (pancytopenia), a very few blasts in the peripheral blood and no or little spleen enlargement (splenomegaly). Cells are usually CD34 positive.
Acute panmyelosis with myelofibrosis
Prefibrotic primary myelofibrosis
Leukemoid reaction
AIDS-related lymphoma
Accelerated phase chronic myelogenous leukemia
Refractory cytopenia of childhood
Diffuse infiltrative lymphocytosis syndrome
Primary myelofibrosis