If the drug is used off-label by crushing the tablet and dissolving it for injection, it may precipitate severe opiate withdrawal symptoms due to the much higher bioavailability of intravenous<unk>  compared to oral<unk> . In simpler terms, the normal injection dose of<unk>  is far smaller than the oral dose due to more of an intravenous dose being absorbed and active in the body.
Oxycodone/naloxone
Buprenorphine/naloxone
Fentanyl/fluanisone
Buprenorphine/naltrexone
Buprenorphine/samidorphan
Dextromethorphan/quinidine
Naloxone
Nalorphine