CBC and blood film: decreased platelets and schistocytes PT, aPTT, fibrinogen: normal markers of hemolysis: increased unconjugated bilirubin, increased LDH, decreased haptoglobin negative Coombs test. Creatinine, urea, to follow renal function ADAMSTS-13 gene, activity or inhibitor testing (TTP).
Thrombotic microangiopathy
Systemic vasculitis
Cryoglobulinemic vasculitis
Lupus vasculitis
Venom-induced consumption coagulopathy
Cerebral vasculitis
Primary fibrinogenolysis
Amyloid purpura