Features that may result from a high level of GH or expanding tumor include: * Headaches – often severe and prolonged * Soft tissue swelling visibly resulting in enlargement of the hands, feet, nose, lips, and ears, and a general thickening of the skin * Soft tissue swelling of internal organs, notably the heart with the attendant weakening of its muscularity, and the kidneys, also the vocal cords resulting in a characteristic thick, deep voice and slowing of speech *<unk>  expansion of the skull at the fontanelle * Pronounced brow protrusion, often with ocular distension (frontal bossing) * Pronounced lower jaw protrusion (prognathism) with attendant macroglossia (enlargement of the tongue) and teeth spacing * Hypertrichosis, hyperpigmentation and hyperhidrosis may occur in these people. * Skin tags * Carpal tunnel syndrome Complications * Problems with bones and joints, including osteoarthritis, nerve compression syndrome due to bony overgrowth, and carpal tunnel syndrome * Hypertension * Diabetes mellitus * Cardiomyopathy, potentially leading to heart failure * Colorectal cancer * Sleep Apnea * Thyroid nodules and thyroid cancer * Hypogonadism * Compression of the optic chiasm by the growth of pituitary adenoma leading to visual problems
symptom of Congenital generalized lipodystrophy
symptom of Laron syndrome
symptoms of Rotor syndrome
symptom of Prader–Willi syndrome
picture of Congenital hypothyroidism
symptom of Scheuermann's disease
symptom of Maroteaux–Lamy syndrome
symptom of Rotor syndrome