The mechanism of disease development is largely unknown, although tissue studies, biochemical studies, and imaging studies provide some insight. Histology Histology is the study of tissue samples using a microscope and special stains. Tissue samples of the brain can be normal. Scarring of the brain, termed gliosis, has been observed, specifically in the CA1 section of the pyramidal layer of the hippocampus. Radiology Radiology is the use of x-rays and radiowaves to create images of the body. At the beginning of the disease, computed tomography (CT) and magnetic resonance imaging (MRI) images are normal. Eventually there can be enlargement of subarachnoid and ventricular spaces of the brain (ie, the areas of the brain that contain fluid rather than brain tissue). Mesial temporal sclerosis has also been observed.
Malignant migrating partial seizures in infancy
Childhood absence epilepsy
Benign familial neonatal seizures
Benign infantile epilepsy
Benign familial infantile epilepsy
Autosomal dominant nocturnal frontal lobe epilepsy
Generalized epilepsy with febrile seizures plus
Benign neonatal seizures