<unk>  is very similar to other axonal degenerative polyneuropathies and therefore can be difficult to diagnose. When<unk> s have sensorimotor polyneuropathy as well as a nutritional deficiency, a diagnosis of<unk>  is often reached. To confirm the diagnosis, a physician must rule out other causes of similar clinical syndromes. Other neuropathies can be differentiated on the basis of typical clinical or laboratory features. Differential diagnoses to<unk>  include amyotrophic lateral sclerosis, beriberi, Charcot-Marie-Tooth disease, diabetic lumbosacral plexopathy, Guillain Barre Syndrome, diabetic neuropathy, mononeuritis multiplex and post-polio syndrome. To clarify the diagnosis, medical workup most commonly involves laboratory tests, though, in some cases, imaging, nerve conduction studies, electromyography, and vibrometer testing may also be used. A number of tests may be used to rule out other causes of peripheral neuropathy. One of the first presenting symptoms of diabetes mellitus may be peripheral neuropathy, and hemoglobin A1C can be used to estimate average blood glucose levels. Elevated blood creatinine levels may indicate chronic kidney disease and may also be a cause of peripheral neuropathy. A heavy metal toxicity screen should also be used to exclude lead toxicity as a cause of neuropathy.<unk> m is normally associated with nutritional deficiencies, which may contribute to the development of<unk> . Thiamine, vitamin B-12, and folic acid are vitamins that play an essential role in the peripheral and central nervous system and should be among the first analyzed in laboratory tests. It has been difficult to assess thiamine status in individuals due to difficulties in developing a method to directly assay thiamine in the blood and urine. A liver function test may also be ordered, as<unk>  consumption may cause an increase in liver enzyme levels.
Alcoholic polyneuropathy
Tropical neuropathy
Diabetic neuropathy
Critical illness polyneuropathy
Chronic inflammatory demyelinating polyneuropathy
Paraneoplastic cerebellar degeneration
Vasculitic neuropathy
Polyneuropathy