<unk> -type<unk><unk>  lipodystrophy, also known as FPLD Type II and abbreviated as (FPLD2), is a rare monogenic form of insulin resistance characterized by loss of subcutaneous fat from the extremities, trunk, and gluteal region. FPLD recapitulates the main metabolic attributes of the insulin resistance syndrome, including central obesity, hyperinsulinemia, glucose intolerance and diabetes usually type 2, dyslipidemia, hypertension, and early endpoints of atherosclerosis. It can also result in hepatic steatosis. FPLD results from mutations in LMNA gene, which is the gene that encodes nuclear lamins A and C. The condition is named after Scottish doctor Matthew<unk> , who pioneered early study into the disorder.
Dunnigan familial partial lipodystrophy
Coffin–Siris syndrome
Maroteaux–Lamy syndrome
Sabinas brittle hair syndrome
Sugarman syndrome
Marfanoid–progeroid–lipodystrophy syndrome
Clouston's hidrotic ectodermal dysplasia
Laurence–Moon syndrome