Recent research suggests that<unk>  is caused by a de novo (spontaneous) genetic mutation in the ATP1A3 gene on chromosome 19 (locus 19q13.31) which encodes enzyme ATP1A3. A small number of cases seem to be caused by a mutation in the ATP1A2 gene. Where the mutation is inherited, it has the autosomal dominant pattern of inheritance. Previously<unk>  was thought to be a form of complicated migraine because of strong family histories of migraine reported in<unk>  cases.<unk>  has also been considered to be a movement disorder or a form of epilepsy. Suggested causes have included channelopathy, mitochondrial dysfunction, and cerebrovascular dysfunction. The disorder most closely related to<unk>  is familial<unk>  migraine which is caused by a mutation in a gene for calcium channel receptors. It was thus thought that<unk>  may be caused by a similar channelopathy.
Alternating hemiplegia of childhood
Chronic paroxysmal hemicrania
Acute cerebellar ataxia of childhood
Ataxic cerebral palsy
Dyskinetic cerebral palsy
Babinski–Nageotte syndrome
Non-progressive congenital ataxia
Infantile progressive bulbar palsy