Mechanism of action The exact mechanism of action for<unk>  is unknown; however, results from animal studies suggest that it acts by blocking seizure propagation and elevating seizure thresholds.<unk>  is thought to modulate both synaptic and extrasynaptic GABAA receptors to normalize over-excited neurons.<unk> 's activation of the extrasynaptic receptor is an additional mechanism that provides stabilizing effects that potentially differentiates it from other drugs that increase GABA signaling.<unk>  binds to allosteric sites of the GABAA receptor to modulate and open the chloride ion channel, resulting in a hyperpolarization of the neuron. This causes an inhibitory effect on neurotransmission, reducing the chance of a successful action potential (depolarization) from occurring.
Ganaxolone
Oxendolone
Stenbolone
Trenbolone
Ciclesonide
Budesonide
Oxymetholone
Mometasone