The most common adverse effects are dizziness, drowsiness, light-headedness, and ataxia.<unk>  has abuse potential and should never be used with alcoholic beverages or any other substance that can cause drowsiness. Addictive and possibly fatal results may occur.<unk>  users should only take this drug strictly as prescribed, and should only be taken directly before the user plans on sleeping a full night. Next day drowsiness is common and may increase during the initial phase of treatment as accumulation occurs until steady-state plasma levels are attained. A 2009 meta-analysis found a 44% higher rate of mild infections, such as pharyngitis or sinusitis, in people taking hypnotic drugs compared to those taking a placebo. In September 2020, the U.S. Food and Drug Administration (FDA) required the boxed warning be updated for all benzodiazepine medicines to describe the risks of abuse, misuse, addiction, physical dependence, and withdrawal reactions consistently across all the medicines in the class. Tolerance, dependence and withdrawal A review paper found that long-term use of<unk>  is associated with drug tolerance, drug dependence, rebound insomnia and central nervous system (CNS) related adverse effects.<unk>  is best used for a short time period and at the lowest possible dose to avoid complications associated with long-term use. Non-pharmacological treatment options however, were found to have sustained improvements in sleep quality.<unk>  and other benzodiazepines such as fosazepam, and nitrazepam lost some of their effect after seven days administration in psychogeriatric patients.<unk>  shares cross tolerance with barbiturates and barbiturates can easily be substituted by<unk>  in those who are habituated to barbiturate sedative hypnotics. After discontinuation of<unk>  a rebound effect or benzodiazepine withdrawal syndrome may occur about four days after discontinuation of medication.
Flurazepam
Halazepam
Oxazepam
Diclazepam
Cinolazepam
Medazepam
Gidazepam
Quazepam