<unk>  is safer than other antiemetics used in veterinary medicine, in part because of its high specificity for its target and thus not binding to other receptors in the central nervous system. Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. Eight percent of dogs taking<unk>  at doses meant to prevent motion sickness vomited right after, likely due to the local effects<unk>  had on the gastrointestinal tract. Small amounts of food beforehand can prevent such post-administration vomiting. One of the most common side effects of subcutaneous administration is moderate to severe pain at the injection site. Although the manufacturer recommends keeping<unk>  at room temperature, many people have noted that keeping it in the fridge reduces the sting upon injection. Only unbound<unk>  causes pain – it is normally formulated with beta-cyclodextrin to increase solubility; at cooler temperatures, more of the<unk>  remains bound to the cyclodextrin, leaving less<unk>  unbound. While there is no pain related to the intravenous administration of<unk> , pushing a dose in too quickly can temporarily reduce blood pressure. Fewer than 1 in 10,000 dogs and cats experience anaphylactic reactions.
Maropitant
Lemborexant
Nefopam
Avacopan
Tofisopam
Verapamil
Fenoldopam
Alvimopan