<unk>  is caused by a mutation on chromosome 11 in the 11p13 region. Specifically, several genes in this area are deleted, including the PAX6 ocular development gene and the Wilms' tumour gene (WT1). Abnormalities in WT1 may also cause genitourinary anomalies. Mutations in the PAX6 gene have recently been shown to not only cause ocular abnormalities, but also problems in the brain and pancreas. The gene for brain-derived neurotrophic factor (BDNF), located on 11p14.1, has been proposed as a candidate gene for the obesity and excessive eating in a subset of<unk>  patients. This strengthens the case for a role for BDNF in energy balance.
WAGR syndrome
Fryns-Aftimos syndrome
CAMFAK syndrome
Harris platelet syndrome
3C syndrome
HUPRA syndrome
Ehlers–Danlos syndromes
Helsmoortel-Van der Aa syndrome