right<unk> s <unk> s), formally<unk> <unk>  receptor type 1 (AT1) antagonists, also known as<unk>  receptor<unk> s,<unk> <unk>  receptor antagonists, or AT1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the<unk> <unk>  receptor type 1 (AT1) and thereby block the arteriolar contraction and sodium retention effects of renin–angiotensin system. Their main uses are in the treatment of hypertension (high blood pressure), diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure. They selectively block the activation of the AT1 receptor, preventing the binding of<unk> <unk>  compared to ACE inhibitors.<unk> s and the similar-attributed ACE inhibitors are both indicated as the first-line antihypertensives in patients developing hypertension along with left-sided heart failure. However,<unk> s appear to produce less adverse effects compared to ACE inhibitors.
Angiotensin II receptor blocker
Calcium channel blocker
ACE inhibitor
Adrenergic blocking agent
SGLT2 inhibitor
Mercurial diuretic
Lipid-lowering agent
Adenosine receptor antagonist