<unk>  (VOD) or<unk><unk><unk>  with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant and/or excessive exposure to hepatotoxic pyrrolizidine alkaloids. It is classically marked by weight gain due to fluid retention, increased liver size, and raised levels of bilirubin in the blood. The name sinusoidal obstruction syndrome (SOS) is preferred if<unk>  happens as a result of chemotherapy or bone marrow transplantation. Apart from chemotherapy,<unk>  may also occur after ingestion of certain plant alkaloids such as pyrrolizidine alkaloids (in some herbal teas), and has been described as part of a rare hereditary<unk>  called<unk>  with immunodeficiency (which results from mutations in the gene coding for a protein called SP110).
Hepatic veno-occlusive disease
Budd–Chiari syndrome
Ischemic hepatitis
Alcoholic liver disease
Autoimmune hepatitis
Alcoholic hepatitis
Congestive hepatopathy
Familial cirrhosis