Pre-gestational<unk>  can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1<unk>  mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2<unk>  mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production. Upon becoming pregnant, the placenta produces human placental lactogen (HPL), a hormone with counter-regulatory actions leading to increased blood glucose levels. In combination with pre-existing<unk> , these maternal physiological changes can lead to dangerously high blood glucose levels. This is significant because the consequences of poor glycemic control are more severe during pregnancy compared to non-pregnant states.
Diabetes and pregnancy
Smoking and pregnancy
Alcohol and pregnancy
Lupus and pregnancy
Domestic violence and pregnancy
HIV and pregnancy
Pregnancy vegetarianism
Drugs in pregnancy