In the majority of immunocompetent individuals,<unk>  resolves without any treatment. Antifungal medications are used to treat severe cases of acute<unk>  and all cases of chronic and disseminated disease. Typical treatment of severe disease first involves treatment with amphotericin B, followed by oral itraconazole. Liposomal preparations of amphotericin B are more effective than deoxycholate preparations. The liposomal preparation is preferred in patients who might be at risk of nephrotoxicity, although all preparations of amphotericin B have risk of nephrotoxicity. Individuals taking amphotericin B are monitored for renal function. Liposomal amphotericin B is better at treating people with progressive disseminated<unk>  and underlying HIV when compared to deoxycholate amphotericin B. Meanwhile, fluconazole performs poorly when compared to other azoles. Treatment with itraconazole must continue for at least a year in severe cases, while in acute pulmonary<unk> , 6 to 12 weeks treatment is sufficient. Alternatives to itraconazole are posaconazole, voriconazole, and fluconazole. Individuals taking itraconazole are monitored for hepatic function.
Histoplasmosis
Tuberculosis
Toxoplasmosis
Talaromycosis
African histoplasmosis
Emmonsiosis
Lobomycosis
Zygomycosis