<unk>  is a synonym for the dimeric form of the pyruvate kinase isoenzyme type<unk>  <unk> M2), a key enzyme within tumor metabolism.<unk>  can be elevated in many tumor types, rather than being an organ-specific tumor marker such as PSA. Increased stool (fecal) levels are being investigated as a method of screening for colorectal tumors, and EDTA plasma levels are undergoing testing for possible application in the follow-up of various cancers. Sandwich ELISAs based on two monoclonal antibodies which specifically recognize<unk>  (the dimeric form of<unk> -PK) are available for the quantification of<unk>  in stool and EDTA-plasma samples respectively. As a biomarker, the amount of<unk>  in stool and EDTA-plasma reflects the specific metabolic status of the tumors.
Tumor M2-PK
Cysteine-rich secretory protein
Tumor-associated glycoprotein 72
Apollophanes of Seleucia
Platelet membrane glycoprotein
Prohormone
Immunoevasin
Heart-type fatty acid binding protein