<unk><unk>  causes gradual enlargement of the thyroid gland, referred to as a goiter. Poor length growth is apparent as early as the first year of life. Adult stature without treatment ranges from , depending on severity, sex, and other genetic factors. Other signs include thickened skin, hair loss, enlarged tongue, and a protruding abdomen. In children, bone maturation and puberty are severely delayed. In adults, ovulation is impeded and infertility is common. Mental deterioration is common. Neurological impairment may be mild, with reduced muscle tone and coordination, or so severe that the person cannot stand or walk. Cognitive impairment may also range from mild to so severe that the person is nonverbal and dependent on others for basic care. Thought and reflexes are slower.
Congenital iodine deficiency syndrome
Congenital hypothyroidism
Congenital adrenal hyperplasia
Lipoid congenital adrenal hyperplasia
Late onset congenital adrenal hyperplasia
Kallmann syndrome
Persistent adrenarche syndrome
Hanhart syndrome