The presentation is dependent upon the underlying cause. The course can be rapid or chronic. * Fatigue * Anorexia * Abdominal pain * Weight loss * Pruritus * Hyperlipidemia * Malabsorption * Fat-soluble vitamin deficiencies * Elevated alkaline phosphatase * Elevated gamma-glutamyltransferase * Elevated conjugated bilirubin
Vanishing bile duct syndrome
Biliary atresia
Congenital hepatic fibrosis
Progressive familial intrahepatic cholestasis
Neonatal cholestasis
Toriello–Carey syndrome
Rubinstein–Taybi syndrome
Adams–Oliver syndrome