Corticosteroids can be used to treat anemia in DBA. In a large study of 225 patients, 82% initially responded to this therapy, although many side effects were noted. Some patients remained responsive to steroids, while efficacy waned in others. Blood transfusions can also be used to treat severe anemia in DBA. Periods of remission may occur, during which transfusions and steroid treatments are not required. Bone marrow transplantation (BMT) can cure hematological aspects of DBA. This option may be considered when patients become transfusion-dependent because frequent transfusions can lead to iron overloading and organ damage. However, adverse events from BMTs may exceed those from iron overloading. A 2007 study showed the efficacy of leucine and isoleucine supplementation in one patient. Larger studies are being conducted.
Diamond–Blackfan anemia
Fanconi anemia
Beta thalassemia
Delta-beta thalassemia
Congenital dyserythropoietic anemia type I
Congenital dyserythropoietic anemia type IV
Congenital dyserythropoietic anemia type II
Congenital dyserythropoietic anemia type III