<unk>  patients may not always experience the all signs and symptoms below. Patients with other medical conditions that are not leukemia may also experience similar symptoms. * Recurrent infections due to lack of normal white blood cells (neutrophils) * Unusual and/or common bleeding and bruising * Extreme tiredness and swellings in the neck (lymph nodes) or the middle of the chest, causing possible facial swelling * Unexplained fevers, chills, and/or night sweats * Unexplained weight loss and/or loss of appetite * Swollen lymph nodes * Unexplained skin itch Clinical manifestations Originating from epigenetic and genetic alterations in immature thymocytes,<unk>  is a highly aggressive and heterogenous disease. Patients often present extensive bone marrow involvement, mediastinal mass, adenopathy, CNS involvement, and splenomegaly. Symptoms can be presented<unk> ly or develop progressively over time. The most common clinical feature amongst patients is the proliferation of malignant clones, hence suppressing normal hematopoiesis, resulting in deficiency of functioning peripheral blood cells (particularly thrombocytes) deficiency.
T-Cell Acute Lymphoblastic Leukemia
T-lymphoblastic leukemia/lymphoma
Adult T-cell leukemia/lymphoma
Atypical chronic myeloid leukemia
T-cell acute lymphoblastic leukemia
Aggressive NK-cell leukemia
T-cell prolymphocytic leukemia
B-cell prolymphocytic leukemia