Global burden of<unk>  calculated as Disability-adjusted life year (DALY) lost per 100,000 people per year. It is estimated that one million severe cases of<unk>  occur annually, with 58,900 deaths. Severe cases account for 5-15% of all<unk>  cases.<unk>  is found in both urban and rural areas in tropical, subtropical, and temperate regions. The global health burden for<unk>  can be measured by disability-adjusted life year (DALY). The score is 42 per 100,000 people per year, which is more than other diseases such as rabies and filariasis. The disease is observed persistently in parts of Asia, Oceania, the Caribbean, Latin America and Africa. Antarctica is the only place not affected by<unk> . In the United States, there were 100 to 150<unk>  cases annually. In 1994,<unk>  ceased to be a notifiable disease in the United States except in 36 states/territories where it is prevalent such as Hawaii, Texas, California, and Puerto Rico. About 50% of the reported cases occurred in Puerto Rico. In January 2013,<unk>  was reinstated as a nationally notifiable disease in the United States. Research on epidemiology of<unk>  in high-risk groups and risk factors is limited in India. The global rates of<unk>  have been underestimated because most affected countries lack notification or notification is not mandatory. Distinguishing clinical signs of<unk>  from other diseases and lack of laboratory diagnostic services are other problems. The socioeconomic status of many of the world's population is closely tied to malnutrition; subsequent lack of micronutrients may lead to increased risk of infection and death due to<unk>  infection. Micronutrients such as iron, calcium, and magnesium represent important areas for future research. Working in a paddy field barefoot is a risk factor for<unk> . The number of cases of<unk>  is directly related to the amount of rainfall, making the disease seasonal in temperate climates and year-round in tropical climates. The risk of contracting<unk>  depends upon the risk of disease carriage in the community and the frequency of exposure. In rural areas, farming and animal husbandry are the major risk factors for contracting<unk> . Poor housing and inadequate sanitation also increase the risk of infection. In tropical and semi-tropical areas, the disease often becomes widespread after heavy rains or after flooding.
Leptospirosis
Rickettsiosis
Bartonellosis
Dengue fever
Typhoid fever
Malaria
Blackwater fever
Murine typhus