Differential diagnosis<unk> -Ab-negative NMO presents problems for diagnosis. The behavior of the oligoclonal bands respect MS can help to establish a more accurate diagnosis. Oligoclonal bands in NMO are rare and they tend to disappear after the attacks, while in MS they are nearly always present and persistent. It is important to notice for differential diagnosis that, though uncommon, it is possible to have longitudinal lesions in MS. Other problem for diagnosis is that<unk> ab in MOGab levels can be too low to be detected. Some additional biomarkers have been proposed.
Anti-AQP4 disease
Adult polyglucosan body disease
Akureyri disease
Anti-NMDA receptor encephalitis
MGUS polyneuropathy
Familial amyloid neuropathy
Anti-VGKC-complex encephalitis
Light chain deposition disease