<unk>  is characterized by profound hearing loss from birth, white hair and pale skin (hair color may darken over time to blond or red). The hearing loss is caused by abnormalities of the inner ear (sensorineural hearing loss) and is present from birth. Individuals with<unk>  often have skin and hair color that is lighter than those of other family members.<unk>  also affects the eyes. The iris in affected individuals is blue, and specialized cells in the eye called retinal pigment epithelial cells lack their normal pigment. The changes to these cells are generally detectable only by an eye examination; it is unclear whether the changes affect vision.
Tietz syndrome
Laurence–Moon syndrome
Landau–Kleffner syndrome
Kapur–Toriello syndrome
Smith–Magenis syndrome
Langer–Giedion syndrome
Aagenaes syndrome
Pelger–Huët anomaly