The diagnosis is based on the patient's sexual history and on physical examination revealing a painless, "beefy-red ulcer" with a characteristic rolled edge of granulation tissue. In contrast to syphilitic ulcers,<unk> lymphadenopathy is generally mild or absent. Tissue biopsy and Wright-Giemsa stain are used to aid in the diagnosis. The presence of Donovan bodies in the tissue sample confirms donovanosis. Donovan bodies are rod-shaped, oval organisms that can be seen in the cytoplasm of mononuclear phagocytes or histiocytes in tissue samples from patients with<unk> . They appear deep purple when stained with Wright's stain. These intracellular inclusions are the encapsulated Gram-negative rods of the causative organisms. They were discovered by Charles Donovan. Classification The first known name for this condition was "serpiginous ulcer", which dates to 1882. The proper clinical designation for donovanosis is<unk> ". A<unk>  is a nodular type of inflammatory reaction, and<unk>  refers to the<unk> region, which is commonly involved in this infection. The disease is commonly known as donovanosis, after the Donovan bodies seen on microscopy, which are a diagnostic sign. The causative organism, Klebsiella<unk> tis, was called Calymmatobacterium<unk> tis, and some sources still use this classification, from the Greek kalymma (a hood or veil), referring to the lesions that contain the bacteria. Prior to this, it was called Donovania<unk> tis, named after the Donovan bodies. The specific name<unk> tis refers to the<unk> tous lesions. The organism was recently reclassified under the genus Klebsiella, a drastic taxonomic change since it involved changing the organism's phylum. However, polymerase chain reaction techniques using a colorimetric detection system showed a 99% similarity with other species in the genus Klebsiella. The clinical appearances of this lesion orally are classified into three types: Ulcerative, exuberant, cicatricial.
Granuloma inguinale
Lichen myxedematosus
Trichostasis spinulosa
Epidermolysis bullosa
Pseudofolliculitis barbae
Tinea imbricata
Hydroa vacciniforme
Cold abscess