The substance is metabolized by the liver enzyme CYP3A4. Consequently, CYP3A4 inducers such as rifampicin or carbamazepine could reduce the effectiveness of<unk> , while CYP3A4 inhibitors such as ketoconazole increase the amount of<unk>  in the body more than 20-fold. Grapefruit juice also increases<unk>  concentrations by inhibiting CYP3A4.
Nisoldipine
Captopril
Nebivolol
Isradipine
Isoprenaline
Azilsartan
Olmesartan
Eplerenone