The<unk>  is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it is<unk> ocated in the right upper quadrant of the abdomen, below the diaphragm. Its other roles in metabolism include the regulation of glycogen storage, decomposition of red blood cells, and the production of hormones. The<unk>  is an accessory digestive organ that produces bile, an alkaline fluid containing cholesterol and bile acids, which helps the breakdown of fat. The gallbladder, a small pouch that sits just under the<unk> , stores bile produced by the<unk>  which is afterwards moved to the small intestine to complete digestion. The<unk> 's highly specialized tissue, consisting of mostly hepatocytes, regulates a wide variety of high-volume biochemical reactions, including the synthesis and breakdown of small and complex molecules, many of which are necessary for normal vital functions. Estimates regarding the organ's total number of functions vary, but textbooks generally cite it being around 500. It is not known how to compensate for the absence of<unk>  function in the<unk> ong term, although<unk>  dialysis techniques can be used in the short term. Artificial<unk> s have not been developed to promote<unk> ong-term replacement in the absence of the<unk> . ,<unk>  transplantation is the only option for complete<unk>  failure.
Liver
Kidney
Lung
Heart
Brain
Central nervous system
Breast
Peripheral nervous system