The mandatory criteria for diagnosis of<unk>  include: * Low numbers of<unk> + cells, on two or more measurements over at least six weeks: *<unk>  cell count less than 300 cells per microliter, or * Less than 20% of T lymphocytes are<unk> + * Laboratory evidence of lack of HIV infection * Absence of any alternative explanation for the<unk><unk>  A one-time finding of low<unk> + cells is usually associated with a recent infection and resolves on its own. Alternative explanations for the low<unk>  counts include conditions such as blood cancers (aleukemia), treatment with chemotherapy, immunosuppressive medications, or other medications that suppress or kill T cells, infections, and problems with blood production. All criteria must be fulfilled for a diagnosis of<unk> . In addition, if these findings are present but combined with other significant findings, such as anemia or thrombocytopenia, then other diagnoses must be considered.
Idiopathic CD4+ lymphocytopenia
Persistent polyclonal B-cell lymphocytosis
Monoclonal B-cell lymphocytosis
X-linked lymphoproliferative disease
Thymic hypoplasia
Dermatopathic lymphadenopathy
Adult-onset immunodeficiency syndrome
CD25 deficiency