<unk>  <unk> , or human<unk> , is a medical condition resulting from not enough growth<unk>  (GH). Generally the most noticeable symptom is that an individual attains a short height. Newborns may also present low blood sugar or a small penis size. In adults there may be decreased muscle mass, high cholesterol levels, or poor bone density.<unk>  can be present at birth or develop later in life. Causes may include genetics, trauma, infections, tumors, or radiation therapy. Genes that may be involved include GH1, GHRHR, or BTK. In a third of cases no cause is apparent. The underlying mechanism generally involves problems with the pituitary gland. Some cases are associated with a lack of other pituitary<unk> s, in which case it is known as combined pituitary<unk><unk> . Diagnosis involves blood tests to measure growth<unk>  levels. Treatment is by growth<unk>  replacement using synthetic human growth<unk> . The frequency of the condition is unclear. Most cases are initially noticed in children. The genetic forms of this disease are estimated to affect about 1 in 7,000 people. Most types occur equally in males and females though males are more often diagnosed.
Growth hormone deficiency
Prader–Willi syndrome
Isolated growth hormone deficiency
Turner syndrome
Thyroid dysgenesis
Noonan syndrome
Congenital hypothyroidism
Small for gestational age