Almost all children with<unk>  have intellectual disabilities, which range from mild to moderate depending upon the number of the deletions of genes from the chromosome. Most have delayed development, including delayed speech, motor disabilities and lack of coordination, which makes simple activities like sitting, standing and walking difficult. Most children eventually start speaking, but in cases with severe intellectual disability language use is highly restricted. They have distinctive facial features like: * Small head (microcephaly) * Pointed forehead (trigonocephaly) * Small ears which are low-set * Widely-spaced eyes (hypertelorism) * Droopy eyelids (ptosis) * Broad nasal bridge * Abnormally thin upper lips * Downturned corners of the mouth * Excess skin covering in the inner corner of eyes (epicanthal folds) Some children also suffer from behavioural problems like distractibility, hyperactivity, impaired communication and social skills, which qualifies them for a diagnosis of ASD and ADHD. Heart defects are very common in children with<unk> . 88.5% of people with the disorder have Paris-Trousseau syndrome, which is a bleeding disorder and causes a lifelong risk of abnormal bleeding and bruising due to dysfunction in the platelets. Other symptoms may include eye problems, ear and sinus infections, hearing problems, bone deformities, growth hormone deficiency, gastrointestinal problems, kidney malfunctions, etc.
Jacobsen syndrome
Senior–Løken syndrome
McGillivray syndrome
Mungan syndrome
Lelis syndrome
Sanjad-Sakati syndrome
Barakat-Perenthaler syndrome
Bart syndrome