Interpretation of antibody panel to detect patient antibodies towards the most relevant human blood group systems. The<unk>  (Co) is present on the membranes of red blood cells and in the tubules of the kidney and helps determine a person's blood type. The Co antigen is found on a protein called aquaporin-1 which is responsible for water homeostasis and urine concentration. The Co antigen is important in transfusion medicine. 99.8% of people possess the Co(a) allele. Individuals with Co(b) allele or who are missing the<unk>  antigen are at risk for a transfusion reaction such as hemolytic anemia or alloimmunization. Antibodies against the<unk>  antigen may also cause hemolytic disease of the newborn, in which a pregnant woman's body creates antibodies against the blood of her fetus, leading to destruction of the fetal blood cells.
Colton antigen system
Lutheran antigen system
Lewis antigen system
Kell antigen system
MNS antigen system
Kidd antigen system
Lan blood group system
Augustine blood group system