<unk>  <unk>  or<unk>  Toxic<unk>  (MTF) is a low-molecular-weight peptide released from the pancreas into the blood in mammals during various shock states.<unk>  is a significant mediator of shock pathophysiology, reducing<unk>  contractility, constricting splanchnic arteries and impairing phagocytosis by the reticuloendothelial system. Survival can be improved by preventing its release or blocking its activity, for example using glucocorticoids, prostaglandins, aprotinin, captopril, imidazole or lidocaine.
Myocardial depressant factor
Norepinephrine releasing agent
Electrolyte exclusion effect
Endogenous agonist
Serotonin releasing agent
Chaotropic agent
Natural neuroactive substance
Serotonin–norepinephrine releasing agent