<unk> is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene<unk> and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more formally known as serine/threonine-protein kinase B-Raf. The<unk> protein is involved in sending signals inside cells which are involved in directing cell growth. In 2002, it was shown to be mutated in some human cancers. Certain other inherited<unk> mutations cause birth defects. Drugs that treat cancers driven by<unk> mutations have been developed. Two of these drugs, vemurafenib and dabrafenib are approved by FDA for treatment of late-stage melanoma. Vemurafenib was the first approved drug to come out of fragment-based drug discovery.
BRAF 
KRAS
ABL 
TFM-4AS-1
Kras
P73
HERG
CoWIN