Thyroid hormone synthesis, this image traces<unk>  from production within the rough endoplasmic reticulum until proteolytic release of the thyroid hormones.<unk>  <unk>  acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Newly synthesized thyroid hormones (T3 and T4) are attached to<unk>  and comprise the colloid within the follicle. When stimulated by thyroid stimulating hormone (TSH), the colloid is endocytosed from the follicular lumen into the surrounding thyroid follicular epithelial cells. The colloid is subsequently cleaved by proteases to release<unk>  from its T3 and T4 attachments. The active forms of thyroid hormone: T3 and T4, are then released into circulation where they are either unbound or attached to plasma proteins, and<unk>  is recycled back into the follicular lumen where it can continue to serve as a substrate for thyroid hormone synthesis.
Thyroglobulin
Gamma globulin
Parathyroid hormone
Hepcidin
Haptocorrin
Modulin
Ovoferrin
Orexin