<unk>  or MV-NIS is an attenuated oncolytic Edmonston (Ed) strain of<unk>  virus. MV-NIS will attach and fuse to host tumor cell membranes. After fusion, MV-NIS has been observed to kill the tumor cells. Due to the unique properties of<unk>  uptake in these cells,<unk>  123 (I-123) may be used to image MV-NIS-infected tumor cells. Non-invasive imaging provides confirmation of targeted infection and allows for monitoring and visualization of treatment progression. The<unk>  CD46 antigen is known to be the functional cellular receptor for<unk>  virus. This type 1 integral membrane glycoprotein is a normal part of<unk>  tissue but may be overexpressed on some cancer cell types. MV-NIS is the first targeted engineered virus therapy to have shown remission in published cancer clinical trials.
Measles virus encoding the human thyroidal sodium iodide symporter
Xenotropic murine leukemia virus–related virus
Yaba monkey tumor virus
Kaposi's sarcoma-associated herpesvirus
Acanthocystis turfacea chlorella virus 1
Dobrava-Belgrade orthohantavirus
Simian foamy virus
SARS-CoV-2 Epsilon variant