Locally produced<unk>  in the vessel wall contributes to the development and progression of atherosclerosis.<unk>  has been described to play a role in renal pathology including acute kidney injury and chronic kidney failure. The chronic activation of monocytes can lead to multiple metabolic, hematologic and immunologic abnormalities in patients with chronic kidney failure. In the context of acute kidney injury,<unk>  has been implicated in promoting repair following injury, but also been described in an opposing role, driving proliferation of a pro-inflammatory<unk>  phenotype.
Macrophage colony-stimulating factor
Macrophage-activating factor
Leukemia inhibitory factor
Hemopoietic growth factor
Thymic stromal lymphopoietin
Interleukin
Major basic protein
Tumor necrosis factor