right Side effects are similar to those of morphine, but<unk> , due to its action at the kappa opioid receptor is more likely to invoke psychotomimetic effects. High dose may cause high blood pressure or high heart rate. It may also increase cardiac work after myocardial infarction when given intravenously and hence this use should be avoided where possible. Respiratory depression is a common side effect, but is subject to a ceiling effect, such that at a certain dose the degree of respiratory depression will no longer increase with dose increases. Likewise rarely it has been associated with agranulocytosis, erythema multiforme and toxic epidermal necrolysis. Tissue damage at injection sites Severe injection site necrosis and sepsis has occurred (sometimes requiring amputation of limb) with multiple injection of<unk>  lactate. In addition, animal studies have demonstrated that<unk>  is tolerated less well subcutaneously than intramuscularly.
Pentazocine
Eptazocine
Esketamine
Trimetazidine
Bremazocine
Etomidate
Flumazenil
Ketamine