Vaccination with vaccinia virus was accompanied with a spectrum of adverse events. Some of them lethal. Generally accepted number of deaths after vaccination with live vaccine is one per one million vaccinations. But during the eradication campaign, more than one vaccination strain was used and these strains differed significantly in causing adverse events. The incidence of PVE was between 44.9 cases per one million vaccinations with Bern strain used in western Europe to 2.9 cases per one million vaccinations with NYCBH strain used in the US. Number of deaths directly connected to PVE also differed from strain to strain. With 11 deaths per one million vaccinations with the Bern strain to 1.2 deaths per one million vaccinations with the NYCBH strain. PVE incidence also depended on the age of the vaccinated person. That is why in the US children up to one year of age and in Europe children up to three years of age were excluded from vaccination.
Postvaccinal encephalitis
Eastern equine encephalitis
Tick-borne encephalitis
Japanese encephalitis
Brain fever
Herpesviral encephalitis
Cryptic rabies
Herpesviral meningitis