<unk>  is an infectious disease caused by the<unk>  virus (CPXV). The virus, part of the genus Orthopoxvirus, is closely related to the vaccinia virus. The virus is zoonotic, meaning that it is transferable between species, such as from cat to human. The transferral of the disease was first observed in dairymaids who touched the udders of infected cows and consequently developed the signature pustules on their hands.<unk>  is more commonly found in animals other than bovines, such as rodents.<unk>  is similar to, but much milder than, the highly contagious and often deadly smallpox disease. Its close resemblance to the mild form of smallpox and the observation that dairy farmers were immune to smallpox inspired the modern smallpox vaccine, created and administered by English physician Edward Jenner. The word "vaccination", coined by Jenner in 1796, is derived from the Latin adjective vaccinus, meaning "of or from the cow". Once vaccinated, a patient develops antibodies that make them immune to<unk> , but they also develop immunity to the smallpox virus, or Variola virus. The<unk>  vaccinations and later incarnations proved so successful that in 1980, the World Health Organization announced that smallpox was the first disease to be eradicated by vaccination efforts worldwide. Other orthopox viruses remain prevalent in certain communities and continue to infect humans, such as the<unk>  virus in Europe, vaccinia in Brazil, and monkeypox virus in Central and West Africa.
Cowpox
Sealpox
Smallpox
Chickenpox
Farmyard pox
Mumps
Rickettsialpox
Progressive vaccinia