It is an acute syndrome requiring aggressive cytoreductive modalities including chemotherapy and/or leukapheresis to both reduce the number of circulating leukocytes and to break apart any aggregates that have already formed. Such rapid and massive lysis of tissue poses a risk of complications (tumor lysis syndrome), but it is necessary to avoid a stroke.<unk>  is different from leukemic infiltration, which is a neoplastic process where leukemic cells invade organs.
Leukostasis
Vasospasm
Leukocytosis
Thrombocytopenia
Allostasis
Cytotoxicity
Cytopenia
Lipotoxicity