The cause of platyspondyly in<unk>  can be attributed in part to odd malformations and structural flaws found in the vertebral bodies of the spinal column in affected infants.<unk>  alters the normal function of chondrocytes, fibroblasts, metaphyseal cells and others associated with cartilage, bone and connective tissues. Overwhelming disorganization of cellular processes involved in the formation of cartilage and bone (ossification), in combination with fibroblastic degeneration of these cells, developmental errors and systemic skeletal malformations describes the severity of this lethal osteochondrodysplasia.
Fibrochondrogenesis
Endochondral ossification
Achondrogenesis
Intramembranous ossification
Heterotopic ossification
Bone resorption
Fibrocartilage callus
Bone remodeling