Though the children affected with CLSD will have problems throughout life, the treatment for this disease thus far is symptomatic. However, prognosis is good; at the time of the most recently published articles, identified children were still alive at over 4 years of age. Mutant proteins still maintain some residual activity, allowing for the release of some collagen, but still form an extremely distended endoplasmic reticulum.
Cranio-lenticulo-sutural dysplasia
Dandy–Walker malformation
Regional odontodysplasia
Congenital fourth nerve palsy
Choroid plexus tumor
Craniodiaphyseal dysplasia
Nasal glial heterotopia
Ischiopatellar dysplasia