The approximate relative levels of the preventable causes of<unk>  in the United States, taken from the article<unk>  prevention. The most significant risk factor is age. According to<unk>  researcher Robert A. Weinberg, "If we lived long enough, sooner or later we all would get<unk> ." Essentially all of the increase in<unk>  rates between prehistoric times and people who died in England between 1901 and 1905 is due to increased lifespans. Although the age-related increase in<unk>  risk is well-documented, the age-related patterns of<unk>  are complex. Some types of<unk> , like testicular<unk> , have early-life incidence peaks, for reasons unknown. Besides, the rate of age-related increase in<unk>  incidence varies between<unk>  types with, for instance, prostate<unk>  incidence accelerating much faster than brain<unk> . It has been proposed that the age distribution of<unk>  incidence can be viewed as the distribution of probability to accumulate the required number of driver events by the given age. Over a third of<unk>  deaths worldwide (and about 75-80% of<unk> s in the United States) are due to potentially modifiable risk factors. The leading modifiable risk factors worldwide are: * tobacco smoking, which is strongly associated with lung<unk> , mouth, and throat<unk> ; * drinking alcohol, which is associated with a small increase in oral, esophageal, breast, liver and other<unk> s; * a diet low in fruit and vegetables, * physical inactivity, which is associated with increased risk of colon, breast, and possibly other<unk> s * obesity, which is associated with colon, breast, endometrial, and possibly other<unk> s * sexual transmission of human papillomavirus, which causes cervical<unk>  and some forms of anal<unk> , vaginal<unk> , vulvar<unk> , penile<unk> , rectal<unk> , and oropharyngeal<unk> . Men with<unk>  are twice as likely as women to have a modifiable risk factor for their disease. Other lifestyle and environmental factors known to affect<unk>  risk (either beneficially or detrimentally) include the use of exogenous hormones (e.g., hormone replacement therapy causes breast<unk> , exposure to ionizing radiation and ultraviolet radiation, and certain occupational and chemical exposures. Every year, at least 200,000 people die worldwide from<unk>  related to their workplace. Millions of workers run the risk of developing<unk> s such as pleural and peritoneal mesothelioma from inhaling asbestos fibers, or leukemia from exposure to benzene at their workplaces. Currently, most<unk>  deaths caused by occupational risk factors occur in the developed world. It is estimated that approximately 20,000<unk>  deaths and 40,000 new cases of<unk>  each year in the U.S. are attributable to occupation.
Epidemiology of cancer
Epidemiology of diabetes
Epidemiology of breast cancer
Epidemiology of metabolic syndrome
Epidemiology of HIV/AIDS
Epidemiology of domestic violence
Psychiatric epidemiology
Comparison of birth control methods