Child When treated with GH, a severely deficient child will begin to grow faster within months. In the first year of treatment, the rate of<unk>  may increase from half as fast as other children are growing to twice as fast (e.g., from 1 inch a year to 4 inches, or 2.5 cm to 10).<unk>  typically slows in subsequent years, but usually remains above normal so that over several years a child who had fallen far behind in his height may grow into the normal height range. Excess adipose tissue may be reduced. Adults GH treatment can confer a number of measurable benefits to severely GH-deficient adults, such as enhanced energy and strength, and improved bone density. Muscle mass may increase at the expense of adipose tissue. Although adults with hypopituitarism have been shown to have a reduced life expectancy, and a cardiovascular mortality rate of more than double controls, treatment has not been shown to improve mortality, although blood lipid levels do improve. Similarly, although measurements of bone density improve with treatment, rates of fractures have not been shown to improve. Effects on quality of life are unproven, with a number of studies finding that adults with<unk>  had near-normal indicators of QoL at baseline (giving little scope for improvement), and many using outdated dosing strategies. However, it may be that those adults with poor QoL at the start of treatment do benefit.
Growth hormone deficiency
Prader–Willi syndrome
Isolated growth hormone deficiency
Turner syndrome
Thyroid dysgenesis
Noonan syndrome
Congenital hypothyroidism
Small for gestational age