The main medical use for<unk>  is for the prevention of migraine and cluster headache.<unk>  is one of a range of medications used for this purpose, other options include propranolol, topiramate, valproic acid, cyproheptadine and amitriptyline. While<unk>  is reasonably effective, its use is limited by side effects, principally drowsiness and weight gain, and it is usually not the first choice medicine for preventing migraines, instead being used as an alternative when other drugs have failed to be effective. It is not effective in relieving migraine attacks once in progress.<unk>  has also been reported as highly effective in a severe case of erythromelalgia, a rare neurovascular disease that is sometimes refractory to the other drugs named above. Other applications for which<unk>  may be used include as an antidepressant, or for the treatment of anxiety or social phobia. Animal studies also suggest that pizotyline could be used in the treatment of serotonin syndrome or MDMA overdose in a similar manner to the closely related antihistamine/antiserotonin medication cyproheptadine.
Pizotifen
Epiestriol
Plerixafor
Vilanterol
Molsidomine
Disopyramide
Bolesatine
Cromoglicic acid