Metformin is the main drug used for treatment, as it is normally used for patients with hyperglycemia. Metformin reduces appetite and improves symptoms of hepatic steatosis and polycystic ovary syndrome. Leptin can also be used to reverse insulin resistance and hepatic steatosis, to cause reduced food intake, and decrease blood glucose levels. Diet<unk>  patients have to maintain a strict diet for life, as their excess appetite will cause them to overeat. Carbohydrate intake should be restricted in these patients. To avoid chylomicronemia,<unk>  patients with hypertriglyceridemia need to have a diet very low in fat.<unk>  patients also need to avoid total proteins, trans fats, and eat high amounts of soluble fiber to avoid getting high levels of cholesterol in the blood.
Congenital generalized lipodystrophy
Familial partial lipodystrophy
Hypohidrotic ectodermal dysplasia
Acquired generalized lipodystrophy
Familial multiple lipomatosis
X-linked hypertrichosis
Yemenite deaf-blind hypopigmentation syndrome
Encephalocraniocutaneous lipomatosis