<unk>  () (brand names Actriol, Arcagynil, Klimadoral), or<unk>  (), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is a minor and weak endogenous estrogen, and the 16β-epimer of estriol (which is 16α-hydroxy-17β-estradiol).<unk>  is (or has previously been) used clinically in the treatment of acne. In addition to its estrogenic actions,<unk>  has been found to possess significant anti-inflammatory properties without glycogenic activity or immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like hydrocortisone (a glucocorticoid). Relative affinities (%) of<unk>  and related steroids Compound Estradiol 2.6 7.9 100 0.6 0.13 8.7 <0.1 Alfatradiol <1 <1 15 <1 <1 ? ? Estriol <1 <1 15 <1 <1 ? ? 16β-Epiestriol <1 <1 20 <1 <1 ? ? 17α-Epiestriol <1 <1 31 <1 <1 ? ? Values are percentages (%). Reference ligands (100%) were progesterone for the , testosterone for the , for the , for the , aldosterone for the , for , and cortisol for .
Epiestriol
Bolesatine
Vilanterol
Penmesterol
Esthiomene
Lifitegrast
Maralixibat chloride
Plerixafor