Spherox is indicated for the repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee (International Cartilage Repair Society ICRS grade III or IV) with defect sizes up to in adults. To prepare the medicine, a small sample is taken by arthroscopy (a type of keyhole surgery) from the patient's cartilage in the knee. The cartilage cells are then grown in the laboratory to prepare a suspension of<unk> unk> . During arthroscopy, the medicine is placed into the damaged area of the patient's cartilage. The<unk> unk>  attach to the cartilage within 20 minutes. People treated with Spherox should follow a specific rehabilitation program including physiotherapy. This allows the<unk> unk>  to fill in the cartilage defect.
Spheroids of human autologous matrix-associated chondrocytes
Autologous cultured chondrocytes on porcine collagen membrane
Demineralized freeze dried bone allograft
Autologous matrix-induced chondrogenesis
Absorbable gelatin sponge
Artificial cartilage
Stem cell transplantation for articular cartilage repair
Articular cartilage stem cell paste grafting