<unk>  has possible associations with numerous neonatal conditions. Intrapartum (during labor)<unk>  may be associated with neonatal pneumonia, meningitis, sepsis, and death. Long-term infant complications like bronchopulmonary dysplasia, cerebral palsy, and Wilson-Mikity syndrome have been associated to the bacterial infection. Furthermore, histological<unk>  may increase the likelihood of newborn necrotizing enterocolitis, where one or more sections of the bowel die. This occurs when the fetal gut barrier becomes compromised and is more susceptible to conditions like infection and sepsis. In addition,<unk>  can act as a risk factor for premature birth and periventricular leukomalacia. Complications For mother and fetus,<unk>  may lead to short-term and long-term issues when microbes move to different areas or trigger inflammatory responses due to infection. Maternal complications * Higher risk for C-section * Postpartum hemorrhage * Endometritis * Bacteremia (often due to Group B streptococcus and Escherichia coli) * Pelvic abscess Mothers with<unk>  who undergo a C-section may be more likely to develop pelvic abscesses, septic pelvic thrombophlebitis, and infections at the surgical site. Fetal complications * Fetal death * Neonatal sepsis Neonatal complications * Perinatal death * Asphyxia * Early onset neonatal sepsis * Septic shock * Neonatal pneumonia *Infant respiratory distress In the long-term, infants may be more likely to experience cerebral palsy or neurodevelopmental disabilities. Disability development is related to the activation of the fetal inflammatory response syndrome (FIRS) when the fetus is exposed to infected amniotic fluid or other foreign entities. This systemic response results in neutrophil and cytokine release that can impair the fetal brain and other vital organs. Compared to infants with clinical<unk> , it appears cerebral palsy may occur at a higher rate for those with histologic<unk> . However, more research needs to be done to examine this association. There is also concern about the impact of FIRS on infant immunity as this is a critical time for growth and development. For instance, it may be linked to chronic inflammatory disorders, such as asthma.
Chorioamnionitis
Placental abruption
Septic abortion
Toxic abortion
Obstructed labour
Prelabor rupture of membranes
Postpartum infections
Chondritis