<unk>  <unk>  is a congenital disorder which presents with a rare abnormal formation of the enamel or external layer of the crown of teeth, unrelated to any systemic or generalized conditions. Enamel is composed mostly of mineral, that is formed and regulated by the proteins in it.<unk>  is due to the malfunction of the proteins in the enamel (ameloblastin, enamelin, tuftelin and amelogenin) as a result of abnormal enamel formation via<unk> . People afflicted with<unk>  may have teeth with abnormal color: yellow, brown or grey; this disorder can afflict any number of teeth of both dentitions. Enamel hypoplasia manifests in a variety of ways depending on the type of<unk>  an individual has (see below), with pitting and plane-form defects common. The teeth have a higher risk for dental cavities and are hypersensitive to temperature changes as well as rapid attrition, excessive calculus deposition, and gingival hyperplasia. The earliest known case of<unk>  is in an extinct hominid species called Paranthropus robustus, with over a third of individuals displaying this condition.
Amelogenesis imperfecta
Danon disease
Panayiotopoulos syndrome
Pedophilia
Progeria
Kufs disease
Xeroderma
Hawkinsinuria