The side-effect profile is comparable to other TCAs and TeCAS and many of the following are due to anticholinergic (which are less prominent than those of most TCAs) and antihistamine effects. Most often seen are: * Dizziness * Drowsiness * Somnolence * Fatigue * Dry mouth (and complications of long-term uncontrolled dry mouth such as dental caries) * Constipation * Vertigo * Nausea (rare, incidence of ~2%) and vomiting * Increased appetite and weight gain * Orthostatic hypotension, hypertension, sinus tachycardia, heart-block, arrhythmias and other cardiac effects * Sexual dysfunction in men: impotence, priapism, delayed ejaculation, anejaculation, decreased libido * Sexual dysfunction in women: decreased libido, vaginal dryness, painful sexual intercourse, anorgasmia * Allergic skin reactions such as rash or urticaria (more often than with other antidepressants). Rarely, severe skin reactions such as erythema multiforme can occur. * Photosensitivity * Agitation, confusion * Induction of hypomania or mania in patients suffering from underlying bipolar affective disorder * Psychotic symptoms * Tremor * Extrapyramidal symptoms * Headache * Seizures (at high doses) * Rare haematological complications: leukopenia and agranulocytosis (dangerous fall in white blood cells) * Fever * Urinary retention<unk>  causes a strong initial sedation (first 2 to 3 weeks of therapy) and is therefore indicated to treat agitated patients or those with suicidal risks. It causes anticholinergic side effects (dry mouth, constipation, confusion, tachycardia) with a lower incidence than amitriptyline. Originally, the manufacturer claimed that<unk>  is better tolerated than other TCAs and TeCAs. However, seizures, leukopenia and skin reactions occur more often with<unk>  than with comparable drugs like amitriptyline.<unk>  has no known potential for abuse and psychological dependence. Withdrawal Withdrawal symptoms frequently seen when treatment with<unk>  is stopped abruptly (agitation, anxiety, insomnia, sometimes activation of mania or rebound depression) are not indicative of addiction and can be avoided by reducing the daily dose of<unk>  gradually by approximately 25% each week. If treatment has to be stopped at once due to medical reasons, the use of a benzodiazepine (e.g. lorazepam, clonazepam, or alprazolam) for a maximum of 4 weeks as needed will usually suppress withdrawal symptoms.
Maprotiline
Ibutilide
Flecainide
Procainamide
Nortilidine
Dofetilide
Tocainide
Colestilan