Stem cell Transplant Treatment for<unk>  varies widely due to the large variability in the subtypes. Due to the lack of research performed in understanding the nature of<unk>  pathogenesis, a majority of cases will often have poor outcomes for the treatment or will relapse. However, new research into new therapy methods have been made to help reduce the mortality rates and risk of relapse. Chemotherapy Chemotherapy is a drug treatment that involves the use of one or more anti-cancer drugs and is currently the most common treatment method used across all subtypes.<unk>  is typically treated using the CHOP regimen in which four anti-cancer drugs; cyclophosphamide, doxorubicin, vincristine, and prednisone are used in combination at a relatively high dosage. However, outcomes of the CHOP regimen are often poor with high relapse rates. Other less common chemotherapy regime which can also be used include; DHAP (dexamethasone, high-dose cytarabine, and cisplatin) and ICE (ifosfamide, carboplatin, etoposide), however, the outcomes of these treatments are often similar to or worse than the CHOP regimen. In order to improve these outcomes chemotherapy has often been used in conjunction with radiotherapy followed by stem cell transplants. Radiotherapy Radiotherapy is the use of radiation to eradicate cancer. As the electron beams in radiotherapy only penetrate to the level of the dermis, it is a common method of treatment for skin lymphoma which may only occur locally such as Cutaneous<unk> , however, it is not recommended for patients with systemic lymphoma conditions. Stem Cell Transplant Stem Cell Transplants are a common method of treatment which can either be used in conjunction with chemotherapy to improve remission and effectiveness or it can be used with relapsed lymphoma patients. Stem cell transplants can either be an autologous stem cell transplant (ASCT) in which the patient donates their own stem cells or an allogeneic stem cell transplant (alloHCT) in which a related or unrelated healthy donor will donate their stem cells to the patient. Stem cells are collected from the bone marrow and are a type of cell capable of self-renewal and can differentiate into all types of cells, this can be utilised for patients with<unk>  and has seen effective results in treating some subtypes, especially Angioimmunoblastic<unk> . Allogenic stem cell transplants are mainly used when the patient lacks adequate healthy stem cells for an autologous stem cell transplant or has relapsed after prior autologous stem cell transplant treatments. However, allogenic transplants pose a risk as it may be toxic to the patient. Proposed solution include improved donor selection and the use of a conditioning regime in which a high dose of a myeloablative treatment is given alongside stem cell transplants to reduce the immune response. Monoclonal Antibodies Monoclonal Antibodies (mAb) utilizes antibodies to target tumours, it induces apoptosis of the tumour through the obstruction of survival pathways. Monoclonal antibodies can be used as a single treatment agent, however, are more effective when used concurrently with chemotherapy to improve survival and remission. Most commonly used monoclonal antibody used to treat<unk>  include; alemtuzumab and denileukin difititox. Nucleoside analogs Nucleoside analogs are a type of antiviral cytotoxic drug used to treat various cancer related diseases. It possesses highly immunosuppressive abilities and acts by inhibiting viral replication and prevent the spread of the cancerous growth. Nucleoside analogs are one of the most active class of drug used to treat<unk> . Other Other non-tradition or new treatment options include: targeted therapy, protease inhibitors, signalling inhibitors, and HDAC inhibitors.
T-cell lymphoma
B-cell lymphoma
Aggressive lymphoma
Mixed-cell lymphoma
Large-cell lymphoma
Hodgkin lymphoma
Non-Hodgkin lymphoma
Thymic carcinoma