The development of birth defects associated with maternal hyperglycemia is multi-factorial. Environmental factors and genetic predisposition (paternal, maternal and offspring genome) are important in<unk> . The diets of<unk>  mothers impacts the rate at which malformations form in their offspring. Furthermore, there is evidence that resistance to certain malformations caused by diabetes is genetic. Epigenetics and its relationship with various environmental factors such as metabolism and diet play a significant role in teratogenesis. Hyperglycemia and associated teratogenic mediators influence DNA methylation, non-coding RNA expression, histone modifications and other epigenetic regulation mechanisms. Research is focused on exploring the impact of<unk>  on methylation signatures, which could potentially serve as a diagnostic biomarker for the condition.
Diabetic embryopathy
Uremic fetor
Fetus in fetu
Toxic abortion
Fetal hydantoin syndrome
Abortion in Brunei
Fetal warfarin syndrome
Heterotopic pregnancy