<unk>  was generally well tolerated in adult patients with partial-onset seizures. The side-effects most commonly leading to discontinuation were dizziness, ataxia, diplopia (double vision), nystagmus, nausea, vertigo and drowsiness. These adverse reactions were observed in at least 10% of patients. Less common side-effects include tremors, blurred vision, vomiting and headache. Gastrointestinal Nausea, vomiting, diarrhea. Central nervous system Dizziness was the most common treatment-related adverse event. Other CNS effects are headache, drowsiness, blurred vision, involuntary movements, memory problems, diplopia (double vision), trembling or shaking of the hands, unsteadiness, ataxia. Psychiatric Panic attacks; agitation or restlessness; irritability and aggression, anxiety, or depression; suicidality; insomnia and mania; altered mood; false and unusual sense of well-being.<unk>  appears to have a low incidence of psychiatric side effects with psychosis reported in only 0.3% of patients. Cardiovascular Postural hypotension, arrhythmias. Allergies Itching, rash, pruritus. Warnings Suicidal behavior and ideation have been observed as early as one week after starting treatment with<unk> , and is an adverse reaction from use of most AEDs. In clinical trials with a medial treatment duration of 12 weeks, the incidence of suicidal ideation was 0.43% among 27,863 patients as opposed to 0.24% among 16,029 placebo-treated patients. Suicidal behavior was observed in 1 of every 530 patients treated. In pregnancy In a study conducted to assess the teratogenic potential of AEDs in the zebrafish embryo, the teratogenicity index of<unk>  was found to be higher than that of lamotrigine, levetiracetam, and ethosuximide.<unk>  administration resulted in different malformations in the neonatal zebrafish depending on dosage.
Lacosamide
Galantamine
Tianeptine
Benzonatate
Gliquidone
Mannitol
Zonisamide
Acotiamide