Like many small molecule tyrosine kinase inhibitors,<unk>  is regarded as well tolerated. The most common side effects reported are diarrhea, fatigue, nausea and rashes. Of note,<unk>  related rash is associated with improved outcome. In clinical studies elevated liver enzymes have been reported. QT prolongation has been observed with the use of<unk>  ditosylate but there are no reports of torsades de pointes. Caution is advised in patients with hypokalaemia, hypomagnesaemia, congenital long QT syndrome, or with coadministration of medicines known to cause QT prolongation. In combination with capecitabine, reversible decreased left ventricular function are common (2%).
Lapatinib
Neratinib
Tucatinib
Dasatinib
Fostamatinib
Ponatinib
Pemigatinib
Capmatinib