<unk>  is an individual's risk of developing an<unk>  during his or her lifetime. There are a range of genetic and environmental risk factors for developing an<unk>  that vary across the population. Genetic and environmental risk factors each account for roughly half of an individual's risk for developing an<unk> ; the contribution from epigenetic (inheritable traits) risk factors to the total risk is unknown. Even in individuals with a relatively low genetic risk, exposure to sufficiently high doses of an addictive drug for a long period of time (e.g., weeks–months) can result in an<unk> . In other words, anyone can become an individual with a substance use disorder under particular circumstances. Research is working toward establishing a comprehensive picture of the neurobiology of<unk> , including all factors at work in propensity for<unk> .
Addiction vulnerability
Psychological resistance
Psychological resilience
Biopsychiatry controversy
Personality pathology
Happy life expectancy
Psychological dependence
Social degeneration