Where chronic<unk>  proctopathy or RAVE is suspected, a thorough evaluation of symptoms is essential. Evaluation should include an assessment of risk factors for alternate causes of<unk> , such as C. difficile colitis, NSAID use, and travel history. Symptoms such as diarrhea and painful defecation need to be systematically investigated and the underlying causes each carefully treated. Testing for parasitic infections (amebiasis, giardiasis) and sexually transmitted infections (Neisseria gonorrhoeae and herpes simplex virus) should be considered. The location of<unk>  treatment is important, as<unk>  directed at regions of the body other than the pelvis (eg brain, chest, etc) should not prompt consideration of<unk>  proctopathy. Endoscopy is the mainstay of diagnosis for<unk>  damage to the rectum, with either colonoscopy or flexible sigmoidoscopy. RAVE is usually recognized by the macroscopic appearances on endoscopy characterized by vascular ectasias. Mucosal biopsy may aid in ruling out alternate causes of<unk> , but is not routinely necessary and may increase the risk of fistulae development. Telangiectasias are characteristic and prone to bleeding. Additional endoscopic findings may include pallor (pale appearance), edema, and friability of the mucosa. Classification<unk>  can occur a few weeks after treatment, or after several months or years: * Acute<unk>  — symptoms occur in the first 3 months after therapy. These symptoms include diarrhea and the urgent need to defecate. *<unk>  associated vascular ectasias (RAVE) and Chronic<unk>  proctopathy — previously known as "chronic<unk> " occur 3-6 months after the initial exposure. RAVE is characterized by rectal bleeding, chronic blood loss and anemia. Chronic<unk>  proctopathy is characterized by urgency, change in caliber and consistency and increased mucus. Severe cases may present with fistulas and strictures which are rare.
Radiation proctitis
Rectitis
Chronic bacterial prostatitis
Granulomatous prostatitis
Acute prostatitis
Cervicitis
Prostatitis
Pelvic inflammatory disease