<unk> , or mucopolysaccharidosis type II (MPS II), is a rare genetic disorder in which large sugar molecules called glycosaminoglycans (or GAGs or mucopolysaccharides) build up in body tissues. It is a form of lysosomal storage disease.<unk>  is caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase (I2S). The lack of this enzyme causes heparan sulfate and dermatan sulfate to accumulate in all body tissues.<unk>  is the only MPS syndrome to exhibit X-linked recessive inheritance. The symptoms of<unk>  are comparable to those of MPS I. It causes abnormalities in many organs, including the skeleton, heart, and respiratory system. In severe cases, this leads to death during the teenaged years. Unlike MPS I, corneal clouding is not associated with this disease.
Hunter syndrome
Mucopolysaccharidosis type I
Laron syndrome
Mucopolysaccharidosis
Sabinas brittle hair syndrome
Malouf syndrome
Hurler syndrome
TORCH syndrome