The main sign of the disease is life-threatening, recurrent bacterial or fungal soft tissue infections. These infections are often apparent at birth and may spread throughout the body. Omphalitis (infection of the umbilical cord stump) is common shortly after birth. Other signs include delayed separation of the umbilical cord, periodontal disease, elevated neutrophils, and impaired wound healing, but not increased vulnerability to viral infections or cancer. Such patients have fever as the manifestation of infection, inflammatory responses are indolent.
Leukocyte adhesion deficiency-1
MBL deficiency
Rh deficiency syndrome
X linked thrombocytopenia
Severe combined immunodeficiency
Myeloperoxidase deficiency
SAPHO syndrome
Common variable immunodeficiency