<unk>  <unk>  ) is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus. With this method, the acrosome reaction is skipped. There are several differences between classic IVF and<unk> . However, the steps to be followed before and after insemination are the same. In terms of insemination,<unk>  needs only one sperm cell per oocyte, while IVF needs 50,000–100,000. This is because the acrosome reaction has to take place and thousands of sperm cells have to be involved in IVF. Once fertilized, the egg is transformed into a proembryo and it has to be transferred to the uterus to continue its development. The first human pregnancy generated by<unk>  was carried out in 1991 by Gianpiero Palermo and his team.
Intracytoplasmic sperm injection
Intracytoplasmic morphologically selected sperm injection
Testicular sperm extraction
Sacrohysteropexy
In vitro fertilisation
Spermatocelectomy
Sperm donation
Assisted reproductive technology