Even with treatment, CNS infection with Acanthamoeba is often fatal, and there are very few recorded survivors, almost all of whom suffered permanent neurocognitive deficits. The prognosis is largely influenced by the time of diagnosis, how virulent and sensitive the Acanthamoeba strain is, and, most crucially, the immune status of the affected person. Due to it commonly being an opportunistic infection, the prognosis is generally poor, with a mortality rate approaching 90%. Sappinia pedata can cause<unk> , however only one case of<unk>  due to S. pedata infection has ever been reported, and the patient survived without any long-term consequences.
Granulomatous amoebic encephalitis
Sappinia amoebic encephalitis
Japanese encephalitis
Eastern equine encephalitis
Rasmussen's encephalitis
Tick-borne encephalitis
Herpesviral encephalitis
La Crosse encephalitis