<unk>  is one of the most common genetic disorders caused by a single gene. The disorder is believed to be caused by mutations to the gene encoding profilaggrin (a protein which is converted to filaggrin, which plays a vital role in the structure of the skin). Around 10% of the population have some detrimental mutations to the profilaggrin gene that is also linked to atopic dermatitis (another skin disorder that is often present with<unk> . The exact mutation is only known for some cases of<unk> . It is generally considered to be an autosomal dominant condition, i.e., a single genetic mutation causes the disease and an affected person has a 50% chance of passing the condition on to their child. There is some research indicating it may be semi-dominant. This means that a single mutation would cause a mild case of<unk>  and mutations to both copies of the gene would produce a more severe case.
Ichthyosis vulgaris
Lamellar ichthyosis
Ichthyosis acquisita
Urticaria pigmentosa
Ichthyosis bullosa of Siemens
Phytophotodermatitis
Pomade acne
Alopecia mucinosa