<unk>  is a hypothesis that attempts to explain the phenomenon in which psychosis (e.g. having hallucinations, which can mean hearing or seeing things that other people do not see or hear) occurs despite treatment with escalating doses of antipsychotics.<unk><unk>  may be caused by the<unk>  receptor D2 antagonizing effect of antipsychotics, causing a compensatory increase in D2 receptors within the brain that sensitizes neurons to endogenous release of the neurotransmitter<unk> . Because psychosis is thought to be mediated—at least in part—by the activity of<unk>  at D2 receptors, the activity of<unk>  in the presence of<unk>  may paradoxically give rise to worsening psychotic symptoms despite antipsychotic treatment at a given dose. This phenomenon may co-occur with tardive dyskinesia, a rare movement disorder that may also be due to<unk><unk> .
Dopamine supersensitivity psychosis
Substance-induced psychosis
Unitary psychosis
Pseudoneurotic schizophrenia
Stimulant psychosis
Myxedema psychosis
Tardive psychosis
Disorganized schizophrenia