Males and females are affected equally. Studies have shown a birth prevalence between 1 in 43,261 and 1 in 1,505,160 live births. These numbers are likely an underestimate of the true number of cases, because newborn screening for MPS-VI is not widely available. Although studies have not revealed an ethnic predisposition, certain groups with a high degree of consanguinity have a higher prevalence of MPS-VI. For example, one study of a population of Turkish immigrants in Germany revealed that this group had a rate of 1 in 43,261; this was approximately ten times higher than the rate of MPS-VI in non-Turkish Germans. In different populations worldwide, MPS-VI made up between 2 and 18.5% of all MPS disorders.
Maroteaux–Lamy syndrome
Mucopolysaccharidosis
Coffin–Siris syndrome
Griscelli syndrome type 2
Dunnigan familial partial lipodystrophy
Wilson–Mikity syndrome
Marfanoid–progeroid–lipodystrophy syndrome
Gianotti–Crosti syndrome