As of 2010, even with the best care, children with infantile<unk>  usually die by the age of 4. Children with the juvenile form are likely to die between the ages 5–15, while the lifespans of those with the adult form will probably not be affected.
Tay–Sachs disease
Sandhoff disease
Fox–Fordyce disease
Leigh syndrome
Bietti's crystalline dystrophy
Neuronal ceroid lipofuscinosis
Akureyri disease
Dejerine–Sottas disease