Treatment No cure for<unk>  is known, and management is primarily supportive.<unk>  cases are often split into two subgroups,<unk> -Richardson, the classic type, and<unk> -Parkinsonism, where a short-term response to levodopa can be obtained. Dyskinesia is an occasional but rare complication of treatment. Amantadine is also sometimes helpful. After a few years the Parkinsonian variant tends to take on Richardson features. Other variants have been described. Botox can be used to treat neck dystonia and blepharospasm, but this can aggravate dysphagia. Two studies have suggested that rivastigmine may help with cognitive aspects, but the authors of both studies have suggested a larger sampling be used. There is some evidence that the hypnotic zolpidem may improve motor function and eye movements, but only from small-scale studies. Rehabilitation Patients with<unk>  usually seek or are referred to occupational therapy, speech-language pathology for motor speech changes typically a spastic-ataxic dysarthria, and physical therapy for balance and gait problems with reports of frequent falls. Evidence-based approaches to rehabilitation in<unk>  are lacking and, currently, the majority of research on the subject consists of case reports involving only a small number of patients. Case reports of rehabilitation programs for patients with<unk>  generally include limb-coordination activities, tilt-board balancing, gait training, strength training with<unk>  resistive exercises, and isokinetic exercises and stretching of the neck muscles. While some case reports suggest that physiotherapy can offer improvements in balance and gait of patients with<unk> , the results cannot be generalized across all<unk>  patients, as each case report followed only one or two patients. The observations made from these case studies can be useful, however, in helping to guide future research concerning the effectiveness of balance and gait training programs in the management of<unk> . Individuals with<unk>  are often referred to occupational therapists to help manage their condition and to help enhance their independence. This may include being taught to use mobility aids. Due to their tendency to fall backwards, the use of a walker, particularly one that can be weighted in the front, is recommended over a cane. The use of an appropriate mobility aid helps to decrease the individual’s risk of falls and makes them safer to ambulate independently in the community. Due to their balance problems and irregular movements, individuals need to spend time learning how to safely transfer in their homes and in the community. This may include rising from and sitting in chairs safely. Due to the<unk>  nature of this disease, all individuals eventually lose their ability to walk and will need to progress to using a wheelchair. Severe dysphagia often follows, and at this point death is often a matter of months.
Progressive supranuclear palsy
Frontotemporal dementia and parkinsonism linked to chromosome 17
Multiple system atrophy
Corticobasal degeneration
Parkinson-plus syndrome
Parkinson's disease
Benign hereditary chorea
Alzheimer's disease