<unk>  can occur in patients through all age groups. People who smoke tobacco cigarettes and have diabetes mellitus are at a higher risk of developing<unk> . Most cases involve people with atherosclerosis problems. Symptoms of<unk>  include: * Pain * Pallor (pale appearance of the<unk>  * Paresthesias (abnormal sensations in the<unk>  * Perishingly cold * Pulselessness * Paralysis These symptoms are called "the six P's'"; they are commonly mis-attributed to compartment syndrome. One more symptom would be the development of gangrene. Immediate medical attention should be sought with any of the symptoms. In late stages, paresthesia is replaced by anesthesia (numbness) due to death of nerve cells. In some cases, gangrene can occur suddenly and spread rapidly, and should be treated within six hours of<unk> . Related conditions When a<unk>  is<unk>  in the non-acute (chronic) setting, the condition is alternatively called peripheral artery disease or critical<unk><unk> , rather than ALI. In addition to<unk><unk> , other organs can become<unk> , causing: * Renal<unk>  (nephric<unk>  * Mesenteric<unk>  * Cerebral<unk>  * Cardiac<unk>
Acute limb ischaemia
Raynaud syndrome
Superficial vein thrombosis
Popliteal artery entrapment syndrome
Diabetic sock
Diabetic foot ulcer
Diabetic foot
Chronic venous insufficiency