<unk>  is defined as hypersensitivity to emotional distress in the context of opioid abuse.<unk>  and Opioid-induced hyperalgesia can be seen with long-term use of illicit street opioids e.g. heroin, and prescription opioids e.g. hydrocodone and oxycodone during withdrawal.
Hyperkatifeia
Dyscalculia
Pattern hair loss
Prognathism
Macroglossia
Corectopia
Prepubertal hypertrichosis
Spermatorrhea