As of 2018, there is no cure for<unk> , and treatment is restricted to manage symptoms and associated problems. Thus, sodium bicarbonate is recommended to treat metabolic acidosis, and antioxidants, among them vitamins E and C, can reduce oxidative damage.
Glutathione synthetase deficiency
Mitochondrial complex II deficiency
N-Acetylglutamate synthase deficiency
Holocarboxylase synthetase deficiency
Mitochondrial trifunctional protein deficiency
Purine nucleoside phosphorylase deficiency
Glutaminase deficiency
Carbamoyl phosphate synthetase I deficiency