<unk> , also known as plasminogen deficiency type 1, is a genetic disorder characterized by a lack of the protein plasminogen, which is responsible for the ability of the body to break down fibrin clots. Plasminogen deficiency leads to an accumulation of fibrin, causing the development of growths (lesions) that can impair normal tissue and organ function and may lead to blindness when these lesions affect the eyes. It is caused by mutations in the PLG gene.
Hypoplasminogenemia
Hemosiderinuria
Aceruloplasminemia
Pentosuria
Pipecolic acidemia
Histidinemia
Galactosemia
Hyperphenylalaninemia