For diagnostic purposes, magnetic resonance imaging (MRI) and (18Ffluorodeoxyglucose) positron emission tomography (FDG-PET) are applied. They measure either atrophy or reductions in glucose utilization. The three clinical subtypes of frontotemporal lobar degeneration, frontotemporal dementia, semantic dementia and progressive nonfluent aphasia, are characterized by impairments in specific neural networks. The first subtype with behavioral deficits, frontotemporal dementia, mainly affects a frontomedian network discussed in the context of social cognition. Semantic dementia is mainly related to the inferior temporal poles and amygdalae; brain regions that have been discussed in the context of conceptual knowledge, semantic information processing, and social cognition, whereas progressive nonfluent aphasia affects the whole left frontotemporal network for phonological and syntactical processing.
medical cause of Frontotemporal dementia
medical cause of Dementia
medical cause of Parkinsonism
complications of Frontotemporal lobar degeneration
symptom of Alzheimer's disease
symptom of Pantothenate kinase-associated neurodegeneration
medical cause of Metachromatic leukodystrophy
symptom of Bannayan–Riley–Ruvalcaba syndrome