Large single doses are generally well tolerated; a patient who took 7.5 g<unk>  (150 tablets) at once showed no relevant symptoms apart from vomiting, slightly decreased white blood cell count, and marginal changes in liver function parameters. Main symptoms of long-term overdosing are infections of unclear origin, mouth ulcers, and spontaneous bleeding, all of which are consequences of its bone-marrow suppression.
Azathioprine
Hydroxychloroquine
Etanercept
Aminophenazone
Tofacitinib
Teriflunomide
Leflunomide
Sirolimus