<unk>  reduces the toxicity of urotoxic compounds that may form after chemotherapy administration.<unk>  is a water-soluble compound with antioxidant properties, and is given concomitantly with the chemotherapeutic agents cyclophosphamide and ifosfamide.<unk>  concentrates in the bladder where acrolein accumulates after administration of chemotherapy and through a Michael addition, forms a conjugate with acrolein and other urotoxic metabolites. This conjugation reaction inactivates the urotoxic compounds to harmless metabolites. The metabolites are then excreted in the urine.
Mesna
Frax
Welt 
Bibic
Favus
Tar 
Erdosteine
Lisp