<unk>  can be diagnosed via flow cytometry and cytochemical stains. Various devices can divide up leukocyte (white blood cell) populations based on their size and peroxidase activity. Specific stains bind to<unk> , and individuals who display large, granulated cells without this stain through flow cytometry typically have<unk> . In this way, it’s apparent when neutrophils are present in an individual but peroxidase activity is absent. Note,<unk>  can cause false positives in the diagnosis of chronic granulomatous disease, a condition which includes dysfunctional NADPH oxidase. Both disorders interfere with neutrophils’ abilities to kill pathogens through reaction with oxidative species. However, chronic granulomatous disease leads to inadequate H2O2 production, while<unk>  is characterized by a lack of<unk>  to interact with present H2O2. Testing with NADPH oxidase-specific assays can lead to positive results for chronic granulomatous disease and negative results for<unk> .
Myeloperoxidase deficiency
MBL deficiency
Leukocyte adhesion deficiency
Adenosine deaminase deficiency
Adenosine deaminase 2 deficiency
Leukocyte adhesion molecule deficiency
Neutrophil-specific granule deficiency
Primary immunodeficiency