Treatment varies depending on the severity of disease. For mild disease, supportive care may be sufficient, including loperamide and a low residue or bland diet. For more severe disease, the immune<unk><unk>  should be discontinued. Corticosteroid therapy is used to decrease inflammation, at a dose of roughly prednisone 1–2 mg per kg of body weight per day. In cases that do not respond to corticosteroid therapy, infliximab may be used. For cases that fail to respond to infliximab, or where infliximab is contraindicated, vedolizumab may be used. Overall, response rates from treatment are 59% for corticosteroids, 81% for infliximab, and 85% for vedolizumab. Surgery with resection of the colon (colectomy) is necessary in some instances, particularly if severe complications occur, such as perforation or toxic megacolon. Fecal calprotectin, a stool test and marker of inflammation, may be used to follow improvement in colitis.
Checkpoint inhibitor induced colitis
Radiation enteropathy
Radiation colitis
Alkylating antineoplastic agent
Lymphocytic colitis
Microscopic colitis
Immunosuppressive drug
NSAID hypersensitivity reactions