<unk>  is an extremely rare disorder that affects females. The exact cause is still unknown due to very limited presented cases worldwide. However, what is known is that it is caused by mutations in the<unk>  gene.<unk>  is a secreted protein that is encoded by the<unk>  gene which is found on chromosome 1. The main function of this gene is to promote female sex development and repress male sex development. The<unk>  gene provides instructions for producing a specific protein that is responsible for the formation of the female reproductive system, the kidneys, and several hormone producing glands. The<unk>  protein is important in regulating the formation of the Mullerian ducts, also known as the paramesonephric duct, which are the structures in the embryo that eventually will develop into the uterus, fallopian tubes, cervix, and the upper part of the vagina. Consequently, this protein is essential in development of the ovaries and development of oocytes, or female egg cells. As said, this disorder can be caused by a mutation in the gene due to a random spontaneous event, or it can be inherited as an autosomal dominant trait. Dominant genetic disorders occur when only a single copy of an abnormal gene is necessary to portray its phenotypic qualities. Based on the laws of normal genetics, the abnormal gene can be inherited from either parent and the risk of passing the gene from affected parent to future offspring is 50% regardless of the sex of the offspring given its dominant properties. However, in this case it is not possible to inherit the gene from a mother because they are infertile therefore meaning that they cannot have children. It is still unknown if this mutation can be inherited from the father or if it is caused by new mutations in the gene.
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