<unk>  <unk>  is a rare<unk>  which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug<unk> . It can lead to cardiac failure, rhabdomyolysis, metabolic acidosis, and kidney failure, and is often fatal. High blood potassium, high blood triglycerides, and liver enlargement, proposed to be caused by either "a direct mitochondrial respiratory chain inhibition or impaired mitochondrial fatty acid metabolism" are also key features. It is associated with high doses and long-term use of<unk>  (> 4 mg/kg/h for more than 24 hours). It occurs more commonly in children, and critically ill patients receiving catecholamines and glucocorticoids are at high risk. Treatment is supportive. Early recognition of the<unk>  and discontinuation of the<unk><unk>  reduces morbidity and mortality.
Propofol infusion syndrome
Neurogenic shock
Induced coma
Spinal shock
Obstructive shock
Cryptic shock
Cardiogenic shock
Septic shock