<unk>  (or fumaric aciduria) is an exceedingly rare autosomal recessive metabolic disorder in Krebs cycle characterized by a<unk>  of the enzyme<unk>  hydratase, which causes a buildup of fumaric acid in the urine, and a<unk>  of malate. Only 13 cases were known worldwide in 1990, after which a cluster of 20 cases was documented in an inbred community in Arizona.
Fumarase deficiency
Enolase deficiency
Dihydropyrimidine dehydrogenase deficiency
Glutaminase deficiency
Phosphofructokinase deficiency
Hexokinase deficiency
Aldolase A deficiency
Transaldolase deficiency