<unk>  <unk>  is a genetic disorder that typically becomes apparent after 6–18 months of age in females. Symptoms include impairments in language and coordination and repetitive movements. Those affected often have slower growth, difficulty walking, and a smaller head size. Complications of<unk>  can include seizures, scoliosis, and sleeping problems. The severity of the condition is variable.<unk>  is due to a genetic mutation in the MECP2 gene, on the X chromosome. It almost always occurs as a new mutation, with less than one percent of cases being inherited from a person's parents. It occurs almost exclusively in girls; boys who have a similar mutation typically die shortly after birth. Diagnosis is based on the symptoms and can be confirmed with genetic testing. There is no known cure for<unk> . Treatment is directed at improving symptoms. Anticonvulsants may be used to help with seizures. Special education, physiotherapy, and braces may also be useful. Many of those with the condition live into middle age. The condition affects about 1 in 8,500 females. It was first described by Austrian pediatrician Andreas<unk>  in 1966. As his writings were in German, they did not become widely known in the English-speaking world. Swedish pediatrician Bengt Hagberg published an English article in 1983 and named the condition after<unk> . In 1999, Lebanese-American physician Huda Zoghbi discovered the mutation that causes the condition.
Rett syndrome
1p36 deletion syndrome
Fragile X syndrome
Angelman syndrome
Poland syndrome
Childhood disintegrative disorder
Fragile X-associated tremor/ataxia syndrome
Snyder–Robinson syndrome