Diagnosis of an IgE-mediated<unk>  is based on the person's history of allergic reactions, skin prick test (SPT), patch test and measurement of<unk>  protein specific serum immunoglobulin E (IgE or sIgE). A negative IgE test does not rule out non-IgE mediated allergy, which is also described as cell-mediated allergy. SPT and sIgE have sensitivities of 55% and 83%, respectively, and specificities of 68% and 38%. These numbers mean that either test may miss diagnosing an existing<unk> , that both could be positive for other food allergens, and that the tests have wide variability leading to a false-positive outcome of 30%. Confirmation is by double-blind, placebo-controlled food challenges, conducted by an allergy specialist. A diagnostic laboratory test is not available for non-IgE-mediated allergies, reflecting the obscure pathophysiology of these conditions. Instead, a person's history of symptoms is studied, and if the symptoms cease with the removal of<unk> , the diagnosis is made.
Soy allergy
Milk allergy
Peanut allergy
Corn allergy
Egg allergy
Poultry allergy
Fruit allergy
Sesame allergy