Serious complications are uncommon, occurring in less than 5% of cases: * CNS complications include meningitis, encephalitis, hemiplegia, Guillain–Barré syndrome, and transverse myelitis. Prior<unk>  has been linked to the development of multiple sclerosis. * Hematologic: Hemolytic anemia (direct Coombs test is positive) and various cytopenias, and bleeding (caused by thrombocytopenia) can occur. * Mild jaundice * Hepatitis with the Epstein–Barr virus is rare. * Upper airway obstruction from tonsillar hypertrophy is rare. * Fulminant disease course of<unk> munocompromised people are rare. * Splenic rupture is rare. * Myocarditis and pericarditis are rare. * Postural orthostatic tachycardia syndrome * Chronic fatigue syndrome * Cancers associated with the Epstein-Barr virus include: Burkitt's lymphoma, Hodgkin's lymphoma and lymphomas in general as well as nasopharyngeal and gastric carcinoma. * Hemophagocytic lymphohistiocytosis Once the acute symptoms of an initial infection disappear, they often do not return. But once infected, the person carries the virus for the rest of their life. The virus typically lives dormant in B lymphocytes. Independent<unk>  of<unk>  may be contracted multiple times, regardless of whether the person is already carrying the virus dormant. Periodically, the virus can reactivate, during which time the person is again<unk> , but usually without any symptoms of illness. Usually, a person with<unk>  has few, if any, further symptoms or problems from the latent B lymphocyte infection. However, in susceptible hosts under the appropriate environmental stressors, the virus can reactivate and cause vague physical symptoms (or may be subclinical), and during this phase, the virus can spread to others.
Infectious mononucleosis
Chronic lymphocytic leukemia
Adult-onset Still's disease
Streptococcal pharyngitis
Post-Ebola virus syndrome
Acute lymphoblastic leukemia
Typhoid fever
Peritonsillar abscess