<unk>  (trade name Chantix and Champix) is a medication used for smoking cessation.<unk>  is also used for the treatment of dry eye disease. The most common side-effects include nausea (feeling sick), insomnia (difficulty sleeping), abnormal dreams, headache and nasopharyngitis (inflammation of the nose and throat). It is a high-affinity partial agonist for the α4β2 nicotinic acetylcholine receptor subtype (nACh) that leads to the release of the neurotransmitter dopamine in the nucleus accumbens reward center of the brain when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation. In this respect it is similar to cytisine and different from the nicotinic antagonist bupropion and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. It is estimated that<unk>  successfully helps one of every eleven people who smoke remain abstinent from tobacco at six months. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
Varenicline
Seltorexant
Ambulatist
Veristrat
Vernakalant
Suvorexant
Icatibant
Daridorexant