The symptoms of this condition are hyperkeratosis, skin ulcer, dyspareunia, endocardium abnormality, vision problems, hepatitis, seizures, hematuria and meningitis. Associated Diseases or Conditions There are a number of disorders associated with<unk>  including endocrine dysfunctions, vitiligo, malabsorption syndromes, neoplasms and others. In most patients,<unk>  is correlated to abnormalities in cell mediated immunity (T-lymphocyte mediated response). The T-lymphocytes fail to produce the necessary cytokines that are required for immunity against Candida. Current effective treatments include antifungal drugs and, for long term remissions, restoration of cellular immunity.<unk>  autoimmune endocrinopathies are sometimes linked to<unk> , but rarely cause systemic disease or septicemia Patients with autosomal-dominant<unk><unk>  may be at risk for epidermoid esophageal cancer due to the nitrosamine compounds produced by<unk>  candida infection.
Chronic mucocutaneous candidiasis
Oral manifestations of systemic disease
Persistent edema of rosacea
Localized lichen myxedematosus
Disseminate and recurrent infundibulofolliculitis
Oral florid papillomatosis
Recurrent toxin-mediated perineal erythema
Chronic undermining burrowing ulcer