Grapefruit and grapefruit juice should be avoided as they may increase the concentration of the drug in the blood.<unk>  is a substrate of CYP3A4 and multidrug resistance-associated protein 2; drugs that inhibit these enzymes will increase the half-life of<unk>  and potentially increase its adverse effects; drugs that activate them may cause<unk>  to be less effective. It inhibits P-glycoprotein, so will change the availability of other drugs that depend on this transporter.
Cabozantinib
Avapritinib
Encorafenib
Sorafenib
Entrectinib
Enasidenib
Dabrafenib
Abrocitinib