<unk>  or Glycerol kinase deficiency, is caused by a rare X-linked recessive genetic disorder caused by a mutation or a deletion in the glycerol kinase gene, located at the locus Xp21.3 of the X chromosome between base pairs 30,653,358 to 30,731,461. Glycerol kinase catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. It is more common in males because they only have one X chromosome, whereas females rarely manifest the disease because they have two X chromosomes. If<unk>  is caused by a mutation in the glycerol kinase gene then it generally causes an isolated glycerol kinase deficiency, resulting in the inability to synthesize triglycerides and glycerophospholipids. If<unk>  results from a deletion of the glycerol kinase gene then it often is part of a contiguous gene deletion syndrome with associated Duchenne muscular dystrophy and adrenal hypoplasia congenita.
Hyperglycerolemia
Hyperprolinemia
Oxyhyperglycemia
Cholemia
Renal glycosuria
Cystinuria
Lipiduria
Hyperglycemia