<unk>  appears to be an<unk> -HIV innate immune<unk>  because it can be observed in vitro with<unk> +<unk> s from unexposed and uninfected healthy individuals. The presence of a<unk>  (CNAR) was first reported in 1986 by researchers in the laboratory of Dr. Jay Levy at the University of California San Francisco (UCSF). It was recognized that<unk> +<unk> s from HIV-infected individuals can suppress HIV replication without directly killing the infected<unk> s. CNAR appears to be mediated by a<unk> +<unk> <unk> -HIV factor (CAF) that has not yet been identified. Other soluble factors can act against HIV including the β-chemokines.
CD8+ cell noncytotoxic anti-HIV response
Innate resistance to HIV
Structure and genome of HIV
Discovery and development of non-nucleoside reverse-transcriptase inhibitors
Viral strategies for immune response evasion
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors
Zinc finger nuclease treatment of HIV
HIV disease progression rates