<unk>  <unk> yl-tertiary-butylamine), with several brand names including Ionamin and Sentis, is a medication used together with diet and exercise to treat obesity. It is taken by mouth for up to a few weeks at a time, after which the beneficial effects no longer occur. It is also available as the combination<unk> /topiramate. Common side effects include a fast heart beat, high blood pressure, trouble sleeping, dizziness, and restlessness. Serious side effects may include abuse but do not include pulmonary hypertension, valvular heart disease as the latter were caused by the fenfluramine component of the fen-phen drug combination. Use is not recommended during pregnancy or breastfeeding, or with SSRIs or MAO inhibitors. It works mainly as an appetite suppressant, likely as a result of being a CNS stimulant. Chemically,<unk>  is a substituted amphetamine.<unk>  was approved for medical use in the United States in 1959. It is available as a generic medication. In 2019, it was the 158th most commonly prescribed medication in the United States, with more than 3million prescriptions.<unk>  was withdrawn from the market in the United Kingdom in 2000, while the combination medication fen-phen, of which it was a part, was withdrawn from the market in 1997 due to side effects of fenfluramine which caused increased levels of circulating of serotonin which stimulated serotonin receptors on heart valves and thus causing valve insufficiency and leading to primary pulmonary hypertension (PPH). According to the NIH (National Institutes of Health) there is no evidence that<unk>  causes PPH.
Phentermine
Mephentermine
Cabergoline
Fluvoxamine
Finerenone
Acebutolol
Fabomotizole
Tadalafil