No cure for<unk>  is known, nor is there a standard course of treatment. Treatment is symptomatic and supportive. Physical therapy may help improve motor skills, and educational programs may help improve communication skills. Seizures are treated with antiepileptic drugs and gastrostomy is used to help maintain adequate food intake and hydration when swallowing difficulties exist. Also, an experimental treatment uses lithium citrate. When a person has<unk> , his or her levels of N-acetyl aspartate are chronically elevated. The lithium citrate has proven in a rat genetic model of<unk>  to be able to significantly decrease levels of N-acetyl aspartate. When tested on a human, the subject's condition reversed during a 2-week wash-out period after withdrawal of lithium. The investigation revealed both decreased N-acetyl aspartate levels in regions of the brain tested and magnetic resonance spectroscopic values that are more characteristic of normal development and myelination. This evidence suggests that a larger controlled trial of lithium may be warranted as supportive therapy for children with<unk> . Experimental gene therapy trial results, published in 2002, used a healthy gene to take over for the defective one that causes<unk> . In human trials, the results of which were published in 2012, this method appeared to improve the life of the patient without long-term adverse effects during a 5-year follow-up.
Canavan disease
Menkes disease
Akureyri disease
CADASIL
White dot syndromes
Keshan disease
Farber disease
Familial British dementia