<unk>  is contraindicated in patients who have active pathological bleeding, since<unk>  can increase bleeding risk and can also cause serious and potentially life-threatening bleeds.<unk>  is also contraindicated in patients who have a history of serious hypersensitivity reaction to<unk>  (e.g. anaphylaxis or anaphylactic shock). The use of<unk>  should also be avoided in patients with mechanical prosthetic heart valves due to the increased risk of thromboembolic events (e.g. valve thrombosis, stroke, and myocardial infarction) and major bleeding associated with<unk>  in this population.
Dabigatran
Apixaban
Enoxaparin sodium
Rivaroxaban
Palladin
Ticlopidine
Ticagrelor
Eptifibatide