<unk> s can have a wide variety of effects depending upon their selectivity for<unk> s. Selective serotonin releasing<unk> s such as fenfluramine and related compounds are described as dysphoric and lethargic in lower doses, and in higher doses some hallucinogenic effects have been reported. Less selective serotonergic<unk> s that stimulate an efflux in dopamine, such as MDMA are described as more pleasant, increasing energy, sociability and elevating mood. Dopamine releasing<unk> s, usually selective for both norepinephrine and dopamine have psychostimulant effect, causing an increase in energy, and elevated mood. Other variables can significantly affect the subjective effects, such as infusion rate(increasing positive effects of cocaine), and expectancy. Selectively noradrenergic drugs are minimally psychoactive, but as demonstrated by ephedrine may be distinguished from placebo, and trends towards liking. They may also be ergogenic, in contrast to reboxetine which is solely a reuptake inhibitor.
Monoamine releasing agent
Dopamine releasing agent
Serotonin releasing agent
Monoamine-depleting agent
Serotonin–norepinephrine releasing agent
Chaotropic agent
Norepinephrine releasing agent
Norepinephrine–dopamine releasing agent