<unk>  <unk>  is a machine-calculated measurement of the average size of<unk> s found in blood and is typically included in blood tests as part of the CBC. Since the average<unk>  size is larger when the body is producing increased numbers of<unk> s, the<unk>  test results can be used to make inferences about<unk>  production in bone marrow or<unk>  destruction problems.<unk>  may be higher when there is destruction of<unk> s. This may be seen in immune thrombocytopenic purpura (ITP), myeloproliferative diseases and Bernard–Soulier syndrome. It may also be related to pre-eclampsia and recovery from transient hypoplasia. Abnormally low<unk>  values may correlate with thrombocytopenia when it is due to impaired production of megakaryocytes in the bone marrow, such as in aplastic anemia. A low<unk>  may indicate inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. A high<unk>  is also a bad prognostic marker in patients with sepsis or septic shock. In addition, low<unk>  may correlate with abnormally small<unk>  size, sometimes a symptom of a spectrum referred to as Wiskott–Aldrich syndrome (WAS), caused by a genetic mutation of the WAS gene. Sample for<unk>  testing is obtained in a Lavender-Top EDTA tube. A typical range of<unk><unk> s is 9.4–12.3 fL (femtolitre), equivalent to spheres 2.65 to 2.9 µm in diameter.
Mean platelet volume
Mean corpuscular hemoglobin
Transferrin saturation
Mean corpuscular hemoglobin concentration
Activated clotting time
Partial thromboplastin time
Red blood cell distribution width
Thrombin time