<unk>  <unk> ,also known as Zinsser-Engman-Cole syndrome, is a rare progressive<unk> l disorder with a highly variable phenotype. The entity was classically defined by the triad of abnormal skin pigmentation, nail dystrophy, and leukoplakia of the oral mucosa, but these components do not always occur.<unk>  is characterized by short telomeres. Some of the manifestations resemble premature ageing (similar to progeria). The disease initially mainly affects the skin, but a major consequence is progressive bone marrow failure which occurs in over 80%, causing early mortality.
Dyskeratosis congenita
Chyloderma
Bromoderma
Keratoderma
Photodermatosis
Chondrodysplasia punctata
X-linked ichthyosis
Iododerma