PEN tumours are always painless, solid masses felt on the skin that, due to their slow-growing nature, typically take many years to grow to a size where they are noticeable. There are never any symptoms associated with systemic disease.
Palisaded encapsulated neuroma
Basal-cell carcinoma
Solitary cutaneous leiomyoma
Melanocytic nevus
Bizarre parosteal osteochondromatous proliferation
Skin appendage
Malignant chondroid syringoma
Neurofibroma