Current studies show no negative side effects of<unk>  due to off target effects in either humans or dogs.<unk>  does not appear to show any inhibitory effect on thrombin-stimulated PGI2 biosynthesis in human endothelial cells, the 5-lipoxygenase in human neutrophils, or the cyclo-oxygenase in a variety of test systems. “Studies failed to detect major off-target effects in preclinical testing in dogs or in Phase 1 clinical trials using healthy adult human subjects.” A possible adverse effect of<unk>  would be thromboxane synthase deficiency due to either too high of a dosage or due to too long administration. Thromboxane synthase deficiency is characterized by mucocutaneous, gastrointestinal, or surgical bleeding. However, this effect has not been studied yet, due to a lack of research in high dosage or long term administration of<unk> .
Furegrelate
Lemborexant
Fosaprepitant
Tezacaftor
Eteplirsen
Protokylol
Prasugrel
Bocasan