<unk>  is contraindicated in people with narcolepsy as it may worsen their symptoms. This is its only absolute contraindication.<unk>  has not been studied in people with severe hepatic impairment and is not recommended in these individuals due to the likelihood of increased<unk>  exposure. On the other hand,<unk>  may be used in people with mild-to-moderate hepatic impairment as well as renal impairment of any severity and no dose adjustment is necessary in these situations. Concomitant use of<unk>  with strong CYP3A4 inhibitors is not recommended due to potential for increased<unk>  exposure while concomitant use of<unk>  with strong CYP3A4 inducers may result in loss of<unk>  exposure and effectiveness.<unk>  should be used carefully in people with a history of drug misuse or alcoholism due to its drug-liking effects and possible misuse potential at doses higher than those approved for therapeutic use. Similarly,<unk>  should be used carefully in people with a history of depression or suicidality as it may rarely increase suicidal ideation. The medication is indicated for use in adults and the elderly but has not been studied in children and adolescents and hence is not recommended for these individuals.<unk>  has shown teratogenic effects in animals such as decreased body weight at doses much higher than the equivalents of those approved for therapeutic use in humans. Teratogenic effects with therapeutic doses of<unk>  in humans have not been established due to lack of research and available data.<unk>  is pregnancy category C in the United States. It is unknown whether<unk>  is present in the breast milk, whether it affects lactation in breastfeeding women, or whether it affects breastfed infants. However,<unk>  has been found to be present in mammary milk in rats and this is likely to be the case in humans as well.<unk>  should be used in pregnant and breastfeeding women only if the potential benefit justifies the potential for harm to the baby.
Suvorexant
Icatibant
Veristrat
Seltorexant
Daridorexant
Rimegepant
Atogepant
Ubrogepant