Common adverse drug reactions associated with systemic<unk>  therapyfound in over 1% of peopleinclude: diarrhea, pseudomembranous colitis, nausea, vomiting, abdominal pain or cramps and/or rash. High doses (both intravenous and oral) may cause a metallic taste. Common adverse drug reactions associated with topical formulationsfound in over 10% of peopleinclude: dryness, burning, itching, scaliness, or peeling of skin (lotion, solution); erythema (foam, lotion, solution); oiliness (gel, lotion). Additional side effects include contact dermatitis. Common side effectsfound in over 10% of peoplein vaginal applications include fungal infection. Rarely in less than 0.1% of people<unk>  therapy has been associated with anaphylaxis, blood dyscrasias, polyarthritis, jaundice, raised liver enzyme levels, renal dysfunction, cardiac arrest, and/or hepatotoxicity. Clostridioides difficile Pseudomembranous colitis is a potentially lethal condition commonly associated with<unk> , but which also occurs with other antibiotics. Overgrowth of Clostridioides difficile, which is inherently resistant to<unk> , results in the production of a toxin that causes a range of adverse effects, from diarrhea to colitis and toxic megacolon. Pregnancy and breastfeeding Use of<unk>  during pregnancy is generally considered safe.<unk>  is classified as compatible with breastfeeding by the American Academy of Pediatrics, however, the WHO categorizes it as "avoid if possible". It is classified as L2 probably compatible with breastfeeding according to Medications and Mothers' Milk. A 2009 review found it was likely safe in breastfeeding mothers, but did find one complication (hematochezia) in a breastfed infant which might be attributable to<unk> . LactMed lists potentially negative gastrointestinal effects in babies whose mothers take it while breastfeeding but did not see that as justification to stop breastfeeding.
Clindamycin
Meropenem
Resistin
Rifamycin
Aztreonam
Cefepime
Levofloxacin
Spiramycin