Of the<unk>  that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly adsorbed onto the bone surface. Once<unk> s are in bone, they have a very long elimination half-life that can exceed ten years.
Bisphosphonate
Phosphate binder
Pamidronic acid
Etidronic acid
Sulfonylurea
Allopurinol
Risedronic acid
Alendronic acid