Due to<unk>  taking 18–24 months after initial exposure to onset, most cases of<unk>  occur in adult animals; the youngest animal to exhibit clinical symptoms of the<unk>  was 15 months. The<unk>  is progressive and always fatal. The first signs are difficulties in movement. The most obvious and consistent clinical sign of<unk>  is weight loss over time. Behavioral changes also occur in the majority of cases, including decreased interactions with other animals, listlessness, lowering of the head, tremors, repetitive walking in set patterns, and nervousness. Excessive salivation and grinding of the teeth also are observed. Most deer show increased drinking and urination; the increased drinking and salivation may contribute to the spread of the<unk> . Loss of fear of humans and appearance of confusion are also common. The APHIS summarized it as:
Chronic wasting disease
Chronic critical illness
Protein–energy malnutrition
Infection-induced anorexia
Renal osteodystrophy
Protein poisoning
Water intoxication
Nutritional challenges of HIV/AIDS