<unk> <unk> , sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the lameness, pain, and lowered range of motion caused by arthritis. It is made of repeat disaccharide units (comprising hexosamine and hexuronic acid), and is similar to<unk> s already present in the cartilage;<unk>  thus easily integrates itself there. In vitro studies have shown it to inhibit the enzymes that degrade cartilage and bone, as well as suppress inflammation and stimulate the synthesis of replacement cartilage. While it can cause an increased risk of bleeding, it is relatively safe and has a high LD50.<unk>  is one of the most widely prescribed joint treatments for horses. While it is widely used, some studies still show conflicting results in terms of efficacy, causing some to claim that<unk>  is not solely responsible for the significant mitigation of arthritis seen in success cases.
Polysulfated glycosaminoglycan
Hyaluronic acid
Pentosan polysulfate
Self-protein
Cerebroside
Tetrameric protein
Lecithin
Conjugated linoleic acid