<unk>  is an inhibitor of the human cytochrome P450 system, particularly the isozyme CYP2C19 (CYP3A4 and CYP2C9 to lesser extent) In theory, therefore,<unk>  decreases the metabolism and increases the concentration of any drug metabolised by these enzymes. In addition, its potential effect on QT interval increases the risk of cardiac arrhythmia if used concurrently with other drugs that prolong the QT interval. Berberine has been shown to exert synergistic effects with<unk>  even in drug-resistant Candida albicans infections.<unk>  may increase the serum concentration of Erythromycin (Risk X: avoid combination).
Fluconazole
Itraconazole
Miconazole
Terbinafine
Posaconazole
Micafungin
Sertaconazole
Fosravuconazole