<unk>  is a coronavirus associated with Severe acute respiratory syndrome coronavirus (SARS-CoV) infected with masked palm<unk> , which infected humans and caused SARS events from 2002 to 2003. The severe acute respiratory syndrome coronavirus (SARS-CoV) is highly similar, with a genome sequence similarity of about 99.8%. Because several patients infected at the early stage of the epidemic had contact with fruit-eating Japanese Raccoon Dog (also called tanuki) in the market, fruit-eating Tanuki may be a direct source of human SARS coronavirus. At the end of 2003, four more people in Guangzhou, China were infected with the disease. Sequence analysis found that the similarity with the Tanuki virus reached 99.9%, and the SARS coronavirus was also caused by cases of Tanuki transmission. A follow-up study of masked palm<unk>  has not been found in a few cases, indicating that fruit tanuki may not be the natural host of SARS coronavirus, but only an intermediate host of the virus from a natural reservoir (bat) to humans. Although the tanuki SARS coronavirus is highly similar to that of human SARS coronavirus, there are a few points in the receptor binding domain (RBD) of burden protein, and the ORF8, which encoded auxiliary protein, has a long 29nt sequence than the human virus. When the virus is infected human by a species barrier, These areas change, which may be related to adapting the new environment.
Civet SARS-CoV
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SARS-CoV-2 Iota variant