<unk>  <unk>  is a severe abnormality of brain development characterized by both microcephaly and hydranencephaly. Signs and symptoms may include severe microcephaly, scalp rugae (a series of ridges), and profound intellectual disability. Familial occurrence of the condition is very rare but it has been reported in a few families. It has been suggested that some cases<unk>  are inherited in an autosomal recessive manner via a loss-of-function mutation of the gene NDE1.
Microhydranencephaly
Hemihydranencephaly
Hydranencephaly
Schizencephaly
Microlissencephaly
Megalencephaly
Lissencephaly
Holoprosencephaly