Depending on the virus of interest and the desired application, RVPs can be pseudotypes, containing a heterologous self-assembling core (typically of lentiviral origin), as well as native envelope proteins corresponding to the studied virus. This type of RVP facilitates exceptional reliability and reproducibility of neutralization assay results, while maintaining antigenicity and safety. Alternatively, for structurally complex viruses such dengue and Zika viruses, RVPs are engineered to be antigenically identical to wild-type virus, using all of the structural proteins of the native virus.
Reporter virus particles
Genetically modified virus
Genetically modified bacteria
Microbial cell factory
Virus counter
Virulence factor
Bacterial adhesin
Tax gene product