<unk>  administration causes a decrease in plasma concentrations showing triphasic kinetics: a mean half life (t1/2) of 2.6 min in the first phase, a mean t1/2 of 1.3 h in the second phase, and a mean t1/2 of 77.3 h in the third phase. Metabolism<unk>  is basically metabolized in the liver by cytochrome P450 (CYP)3A4/5 > CYP2C8, which result in seven plasma metabolites and excreted 20 metabolites. During 14 days after administration, 80% of<unk>  is excreted: 76% in the feces and 3.7% as a renal excretion.
Cabazitaxel
Docetaxel
Paclitaxel
Doxorubicin
Ifosfamide
Lipoplatin
Bendamustine
Normustine