Buboes in a male These are only local and no systemic manifestations are present. The ulcer characteristically: * Ranges in size dramatically from 3 to 50 mm (1/8 inch to two inches) across * Is painful * Has sharply defined, undermined borders * Has irregular or ragged borders, described as saucer-shaped. * Has a base that is covered with a gray or yellowish-gray material * Has a base that bleeds easily if traumatized or scraped * painful swollen lymph nodes occurs in 30 to 60% of patients. * dysuria (pain with urination) and dyspareunia (pain with intercourse) in females About half of infected men have only a single ulcer. Women frequently have four or more ulcers, with fewer symptoms. The ulcers are typically confined to the genital region most of the time. The initial ulcer may be mistaken as a "hard" chancre, the typical sore of primary syphilis, as opposed to the "soft chancre" of<unk> . Approximately one-third of the infected individuals will develop enlargements of the inguinal lymph nodes, the nodes located in the fold between the leg and the lower abdomen. Half of those who develop swelling of the inguinal lymph nodes will progress to a point where the nodes rupture through the skin, producing draining abscesses. The swollen lymph nodes and abscesses are often referred to as buboes. Complications * Extensive lymph node inflammation may develop. * Large inguinal abscesses may develop and rupture to form draining sinus or giant ulcer. * Superinfection by Fusarium and Bacteroides. These later require debridement and may result in disfiguring scars. * Phimosis can develop in long-standing lesion by scarring and thickening of foreskin, which may subsequently require circumcision. Sites For<unk>  Lesions Males * Internal and external surface of prepuce. * Coronal sulcus * Frenulum * Shaft of penis * Prepucial orifice * Urethral meatus * Glans penis * Perineum area Females * Labia majora is most common site. "Kissing ulcers" may develop. These are ulcers that occur on opposing surfaces of the labia. * Labia minora * Fourchette * Vestibule * Clitoris * Perineal area * Inner thighs
Chancroid
Genital herpes
Tinea manuum
Demodicosis
Tinea faciei
Lentigo simplex
Tinea capitis
Melanosis coli