<unk>  is caused by abnormal white blood cells (T-lymphocytes). These abnormal cells have a preference for localizing and proliferating uncontrolled in the outer layer of the skin (epidermis). The abnormal cells may later involve other organs such as the lymph nodes. It is hypothesized that the genetic mutations in these cancer cells lead to increased growth and escape from programmed cell death. Additionally, the disease is an unusual expression of CD4 T cells, a part of the immune system. These T cells are skin-associated, meaning they are biochemically and biologically most related to the skin, in a dynamic manner.<unk>  is the most common type of cutaneous T-cell lymphoma (CTCL), but there are many other types of CTCL that have nothing to do with<unk>  and these disorders are treated differently.
Mycosis fungoides
Sycosis vulgaris
Keratoderma climactericum
Tinea versicolor
Lymphomatoid papulosis
Actinic granuloma
Diabetic dermadrome
Granuloma faciale