<unk>  also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich peptide hormone derived from adipose tissue that in humans is encoded by the RETN gene. In primates, pigs, and dogs,<unk>  is secreted by immune and epithelial cells, while, in rodents, it is secreted by adipose tissue. The length of the<unk>  pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa.<unk>  is an adipose-derived hormone (similar to a cytokine) whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM).<unk>  has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease ...<unk>  increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. As a result, the liver is less able to clear 'bad' cholesterol from the body.<unk>  accelerates the accumulation of LDL in arteries, increasing the risk of heart disease. ...<unk>  adversely impacts the effects of statins, the main cholesterol-reducing drug used in the treatment and prevention of cardiovascular disease."
Resistin
Colistin
Meropenem
Teicoplanin
Vancomycin
Ertapenem
Daptomycin
Monobactam