Blood tests are needed to differentiate FX deficiency from other bleeding disorders. Typical are normal thrombin time, prolonged prothrombin time (PT) and prolonged partial thromboplastin time(PTT). FX antigen and its coagulant activity can be used to classify the severity of the condition: # Type I has low levels of FX antigen and activity. # Type II has low coagulant activity but normal or borderline FX antigen levels. The FX (F10) gene is found on chromosome 13q34. Heterogeneous mutations have been described in FX deficient patients.
Factor X deficiency
Factor I deficiency
Factor VII deficiency
Factor XIII deficiency
Factor XII deficiency
Protein S deficiency
Protein C deficiency
COAT platelet defect