Reductions in morbidity and mortality are due to the use of antiviral treatments such as vidarabine and acyclovir. However, morbidity and mortality still remain high due to diagnosis of DIS and CNS<unk>  coming too late for effective antiviral administration; early diagnosis is difficult in the 20–40% of infected neonates that have no visible lesions. A recent large-scale retrospective study found disseminated NHSV patients least likely to get timely treatment, contributing to the high morbidity/mortality in that group. Harrison's Principles of Internal Medicine recommends that pregnant women with active genital<unk>  lesions at the time of labor be delivered by caesarean section. Women whose<unk>  is not active can be managed with acyclovir. The current practice is to deliver women with primary or first episode non-primary infection via caesarean section, and those with recurrent infection vaginally (even in the presence of lesions) because of the low risk (1–3%) of vertical transmission associated with recurrent<unk> .
Neonatal herpes simplex
Neonatal tetanus
Congenital syphilis
Neonatal lupus erythematosus
Neonatal conjunctivitis
Congenital cutaneous candidiasis
Mumps
Neonatal meningitis