Routine antenatal antibody screening blood tests (indirect Coombs test) do not screen for ABO HDN. If IgG anti-A or IgG anti-B antibodies are found in the pregnant woman's blood, they are not reported with the test results, because they do not correlate well with ABO HDN. Diagnosis is usually made by investigation of a<unk>  baby who has developed jaundice during the first week of life. Testing * Coombs - after birth baby will have a direct coombs test run to confirm antibodies attached to the infant's red blood cells. This test is run from cord blood. In some cases, the direct coombs will be negative but severe, even fatal HDN can occur. An indirect coombs needs to be run in cases of anti-C, anti-c, and anti-M. Anti-M also recommends antigen testing to rule out the presence of HDN. * Hgb - the infant's hemoglobin should be tested from cord blood. * Reticulocyte count - Reticulocytes are elevated when the infant is producing more blood to combat anemia. A rise in the retic count can mean that an infant may not need additional transfusions. Low retic is observed in infants treated with IUT and in those with HDN from anti-Kell * Neutrophils - as Neutropenia is one of the complications of HDN, the neutrophil count should be checked. * Thrombocytes - as thrombocytopenia is one of the complications of HDN, the thrombocyte count should be checked. * Bilirubin should be tested from cord blood. * Ferritin - because most infants affected by HDN have iron overload, a ferritin must be run before giving the infant any additional iron. *<unk>  Screening Tests - Transfusion with donor blood during pregnancy or shortly after birth can affect the results of the<unk>  Screening Tests. It is recommended to wait and retest 10–12 months after last transfusion. In some cases, DNA testing from saliva can be used to rule out certain conditions.
Hemolytic disease of the newborn 
Neonatal meningitis
Neonatal hepatitis
Michelin tire baby syndrome
Neonatal diabetes
Shaken baby syndrome
Twin-to-twin transfusion syndrome
Neonatal toxic shock-like exanthematous disease