In contrast to the<unk> + cell depletion caused by HIV, in general, patients with<unk>  have a good prognosis. The decline in<unk> + T-cells in patients with<unk>  is generally slower than that seen in HIV-infected patients. The major risk to people with<unk>  is unexpected infections, including cryptococcus, atypical mycobacterial and Pneumocystis jiroveci pneumonia (PCP). The condition may also resolve on its own.<unk>  sometimes precedes and may be the first signal of several blood cancers.<unk>  patients have developed primary effusion lymphoma, primary leptomeningeal lymphoma, diffuse large cell lymphoma, MALT lymphoma, and Burkitt's lymphoma, among others.<unk>  may indirectly trigger autoimmune diseases. It has been associated with several cases of autoimmune disease Sjögren syndrome. Because all of the reported autoimmune diseases and lymphomas involve B cells, one hypothesis proposes that<unk> 's narrow T cell repertoire predisposes the immune system to B cell disorders.
Idiopathic CD4+ lymphocytopenia
Persistent polyclonal B-cell lymphocytosis
Monoclonal B-cell lymphocytosis
X-linked lymphoproliferative disease
Thymic hypoplasia
Dermatopathic lymphadenopathy
Adult-onset immunodeficiency syndrome
CD25 deficiency