<unk> /atropine, also known as co-phenotrope, is a combination of the medications<unk>  and atropine, used to treat diarrhea. It should not be used in those in whom Clostridioides difficile infection is a concern. It is taken by mouth. Onset is typically within an hour. Side effects may include abdominal pain, angioedema, glaucoma, heart problems, feeling tired, dry mouth, and trouble seeing. It is unclear if use in pregnancy is safe and use when breastfeeding may result in side effects in the baby. It works by decreasing contractions of the bowel. The combination was approved for medical use in the United States in 1960. It is available as a generic medication and over the counter. In 2019, it was the 339th most commonly prescribed medication in the United States, with more than 900thousand prescriptions. It is sold under the brand name Lomotil among others. The medication is in Schedule V in the United States.
Atropine/diphenoxylate
Desloratadine/pseudoephedrine
Pseudoephedrine/loratadine
Cinnarizine/dimenhydrinate
Sodium nitrite/sodium thiosulfate
Oxycodone/naloxone
Octatropine methylbromide
Fentanyl/fluanisone