<unk>  (LPF-NT) is an extremely rare soft tissue<unk>  first described by Agaram et al in 2016. As of mid-2021, at least 39 cases of LPF-NT have been reported in the literature. LPF-NT<unk> s have several features that resemble<unk>  (LPF)<unk> s, malignant peripheral nerve sheath<unk> s, spindle cell sarcomas, low-grade<unk><unk> s, peripheral nerve sheath<unk> s, and other less clearly defined<unk> s; Prior to the Agaram at al report, LPF-NTs were<unk> ly diagnosed as variants or atypical forms of these<unk> s. The analyses of Agaram at al and subsequent studies uncovered critical differences between LPF-NT and the other<unk>  forms which suggest that it is a distinct<unk>  entity differing not only from<unk>  but also the other<unk>  forms. LPF-NTs are locally invasive, are commonly treated by surgical excision, and have a relatively high rate of local recurrence if their surgical excisions are incomplete. They are generally considered to be benign, non-metastasizing (i.e. not spreading to other parts of the body)<unk> s. However, one case of LFT-NT reported by Agaram et al was associated with metastasis, apparently as a result of the<unk> 's cells transformation into a malignant sarcoma. Further studies are needed to determine the frequency of such cases and the overall metastatic potential of LPF-NT. LPF-NTs were given the<unk><unk> " terminology because in at least some cases: 1) their<unk>  cells express S100 and CD34 but not SOX10 proteins, a pattern that is often found in<unk>  and neuroectodermal<unk>  cells; and 2) their histopathology consists of<unk>  cell infiltrations into adipose tissues in a pattern that is very similar to that found in some low grade malignant peripheral nerve sheath<unk> s.
Lipofibromatosis-like neural tumor
Neural fibrolipoma
Eccrine angiomatous hamartoma
Embryonal tumour with multilayered rosettes
Folliculosebaceous cystic hamartoma
Intranodal palisaded myofibroblastoma
Perivascular epithelioid cell tumour
Aggressive angiomyxoma