Pharmacodynamics Like other azapirones,<unk>  acts as a selective partial agonist of the 5-HT1A receptor. Unlike its relative buspirone, however,<unk>  has greater efficacy in activating the 5-HT1A and has negligible affinity for the D2 receptor (30- to 50-fold lower in comparison to buspirone). However, similarly to buspirone,<unk>  metabolizes into 1-(2-pyrimidinyl)piperazine, which is known to act as a potent antagonist of the α2-adrenergic receptor.
Gepirone
Cabergoline
Fabomotizole
Lumasiran
Tesamorelin
Protollin
Givosiran
Avacopan