<unk>  works as an oxytocic, antihemorrhagic and uterotonic drug in the peripheral nervous system. The most common causes of postpartum hemorrhage are lack of tone in the uterus from overstretching or the use of an anesthetic.<unk>  functions as an agonist at peripheral oxytocin receptors, particularly in the myometrium, with lesser affinity for myoepithelial cells. Oxytocin receptors are G protein-coupled and their mechanism of action involves second messengers and the production of inositol phosphates.<unk>  mimics this mechanism. Binding for<unk>  and other oxytocin agonists has been shown to be nonselective at the extracellular N-terminus and loops E2 and E3. While the oxytocin receptor shows equal affinity for oxytocin and<unk> , the biological effect of<unk>  is almost 50% that of endogenous or exogenous oxytocin.<unk>  has a much longer lasting effect than oxytocin, necessitating only a single dose.<unk>  inhibits endogenous oxytocin release, interrupting the uterine feedback loop with the hypothalamus and decreasing both central and peripheral release of oxytocin. During pregnancy, the synthesis of oxytocin receptors in the uterus greatly increases, reaching a peak during labor and delivery. Consequently, the administration of<unk>  or another oxytocin analog during or immediately following birth will have increased uterotonic and contractile effect. The application of<unk>  does not affect a non-pregnant uterus with lower oxytocin receptor expression.<unk>  also functions to thicken the blood, further preventing post-partum hemorrhage.<unk>  should not be used to induce or augment labor since it could cause cardiac or respiratory distress to mother or infant.
Carbetocin
Betamethasone
Chloroxylenol
Oxytocin 
Oxytocin
Progestogen 
Progestogen
Psilocin