The diet has been described by nutritionists as unhealthy and unbalanced. A 2011 review concluded that a "long-term effect of<unk> s is neither consistent nor conclusive." A 2014 review noted that<unk> s from animal sources should be handled with caution.<unk> s can increase levels of ketones in the blood (ketosis) which may lead to<unk>  levels of uric acid, a risk factor for gout and kidney stones.<unk>  protein intake on the order of 200 g per day, coupled with inadequate intake of other calorie sources (fat or carbohydrates), can cause a form of metabolic disturbance and death commonly known as protein poisoning. Even when consuming other calorie sources, consuming more than 285 g of protein per day (for an 80 kg person) may be unsafe. A 2017 review indicated that a<unk>  may contribute to life-long risk of kidney damage, including chronic kidney disease. Although this was disputed in a different review, a year later.<unk> s may increase the risk of coronary artery disease, cancer and osteoporosis. Vitamin B deficiencies can develop if the diet is followed chronically, and negative effects associated with the diet may include bad breath, constipation, fatigue, and nausea. A 2020 review found that a<unk>  does not significantly improve blood pressure and glycemic control in people with diabetes.
High-protein diet
Low-protein diet
Low-carbohydrate diet
Very-low-calorie diet
Elemental diet
Fad diet
Plant-based diet
Low-fat diet