Risk factors that can promote the development of TACO include conditions that predispose individuals to excess fluid in the<unk>  system (liver failure causing low levels of protein in the blood (hypoalbuminemia), heart failure, renal insufficiency, or nephrotic syndrome), conditions that place increased stress on the respiratory system (lung disease), and conditions necessitating large volume transfusions (severe anemia). Age has also been found to be a risk factor where individuals less than 3 years old and over 60 years old are at increased risk. In addition, the risk of TACO increases as the number of units of blood products transfused increases. Table 1 shows the volume transfused with each blood product. Multiple blood products and blood products with larger volumes increase the risk for TACO. +Table 1 - List of Blood Products and Transfusion Volume Blood Product Volume (mL) Whole blood 520 mL Red Blood Cells 340 mL Concentrated platelets 50 mL Platelets 300 mL Cryoprecipitate 225 mL Fresh frozen plasma 15 mL
Transfusion associated circulatory overload
Transfusion-related acute lung injury
Transfusion-related immunomodulation
Tumor lysis syndrome
Transfusion transmitted infection
Delayed hemolytic transfusion reaction
Acute hemolytic transfusion reaction
Culture-bound syndrome