<unk>  causes lactic acidosis and hyperammonaemia. Lactic acidosis may then lead to liver failure, hepatomegaly, reduced ketone body synthesis, and demyelination of neurons.
Pyruvate carboxylase deficiency
Pyruvate kinase deficiency
Glutaminase deficiency
3-Methylcrotonyl-CoA carboxylase deficiency
Malonyl-CoA decarboxylase deficiency
Multiple carboxylase deficiency
Enolase deficiency
Hexokinase deficiency