<unk> s can be indicated for the prophylaxis and treatment of infections caused by bacteria susceptible to this particular form of antibiotic. First-generation<unk> s are active predominantly against Gram-positive bacteria, such as Staphylococcus and Streptococcus. They are therefore used mostly for skin and soft tissue infections and the prevention of hospital-acquired surgical infections. Successive generations of<unk> s have increased activity against Gram-negative bacteria, albeit often with reduced activity against Gram-positive organisms. The antibiotic may be used for patients who are allergic to penicillin due to the different β-lactam antibiotic structure. The drug is able to be excreted in the urine.
Cephalosporin
Sulfonamide 
Extended-spectrum penicillin
Quinolone antibiotic
Tetracycline
Minocycline
Anthopleurin
Penicillin