The most frequently encountered adverse events related to<unk>  therapy are lead fracture or lead dislodgement. Other reported complications include: * Infection and bleeding at the IPG implantation site * Accumulation of fluid in the pericardium (pericardial effusion) These side effects are similar to those that occur with other electrical stimulation therapies, such as pacemakers, CRT devices or ICD devices. Furthermore, recorded complications did not differ between patients with activated or deactivated<unk>  devices. Overall,<unk>  treatment was demonstrated to have no negative impact on health markers. Precautions Metal detectors used for security screening Similarly to patients with other electrical stimulation devices, patients with a<unk>  device must follow certain precautions arising from the device implantation and its function. * Electromagnetic fields: Strong electromagnetic fields can interfere with the function of the device. Most interference will lead to inhibition of<unk>  signal delivery. Once away from the field, the device will resume its normal function in most cases. The electromagnetic fields of household appliances are usually considered harmless. * Mobile phones: Similarly to other electrical stimulation devices, such as pacemakers, aside from a recommended safety distance of 10–15 cm (4-6 inches) between the device and mobile phones, there are no restrictions on the use of mobile phones. * Security checks: Full body or hand-held metal detectors, such as those used at airport security controls, do not usually affect the function of the device. However, where such detectors are used there are often signs warning people with<unk>  pacemakers and defibrillators, and<unk>  patients are therefore advised to present their device ID. In these cases, the security check will typically continue with the use of a hand-held metal detector or by physical inspection. * Sports: All sports associated with increased stress on the arms or the chest, such as body building, martial arts or tennis, are usually not permitted. Diving is only permitted up to a depth of 5 meters due to the high pressure at greater depth. * Magnetic Resonance Imaging (MRI): Similarly to other electrical stimulation devices, such as pacemakers,<unk>  therapy is a contraindication for MRI, a medical imaging technique.
Cardiac contractility modulation
Vascular recruitment
Isolytic muscle contraction
Neural facilitation
Local blood flow regulation
Vasodilation
Vasoconstriction
Cardioprotection