<unk>  (also known as MYH-associated polyposis) is an autosomal recessive polyposis syndrome. The disorder is caused by mutations in both alleles (genetic copies) of the DNA repair gene,<unk> . The<unk>  gene encodes a base excision repair protein, which corrects oxidative damage to DNA. Affected individuals have an increased risk of colorectal cancer, precancerous colon polyps (adenomas) and an increased risk of several additional cancers. About 1–2 percent of the population possess a mutated copy of the<unk>  gene, and less than 1 percent of people have the<unk>  syndrome. The presence of 10 or more colon adenomas should prompt consideration of<unk> , familial adenomatous polyposis and similar syndromes.
MUTYH-associated polyposis
Familial adenomatous polyposis
Serrated polyposis syndrome
Juvenile polyposis syndrome
Peutz–Jeghers syndrome
Hereditary nonpolyposis colorectal cancer
Attenuated familial adenomatous polyposis
Nijmegen breakage syndrome