Coronal Image of a<unk>  and a Normal Control<unk>  (thin-outside-fat-inside) is used to describe lean individuals with a disproportionate amount of fat (adipose tissue) stored in their abdomen. The figure to illustrate this shows two men, both 35 years old, with a BMI of 25 kg/m2. Despite their similar size, the<unk>  had 5.86 litres of internal fat, whilst the healthy control had only 1.65 litres. Subjects defined as<unk>  with body mass index (BMI) 2 have increased levels of many of the risk factors associated with the metabolic syndrome. This phenotype is a further refinement of “metabolically-obese normal-weight" (MONW). Subjects defined as<unk>  have been described as being at higher risk of developing insulin resistance and type II diabetes due to the fact that they have reduced physical activity/VO2max, reduced insulin sensitivity, higher abdominal adiposity, and a more atherogenic lipid profile. Another important characteristic observed in this cohort is elevated levels of liver fat. It is shown that overconsumption of fructose can lead to<unk>  by inducing inflammation associated cortisol release.
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