Both blood and the urine can be tested for the light chains, which may form amyloid deposits, causing disease. However, the diagnosis requires a sample of an affected organ. Other diagnosis can be tissue biopsy. Tissue biopsy tests a tissue sample to look for amyloid deposits. The tissue is stained with red dye, and under a microscopic examination, amyloid proteins can be detected if the tissue turns an apple-green color.
AL amyloidosis
Giant cell arteritis
AA amyloidosis
Secondary systemic amyloidosis
Monoclonal gammopathy of undetermined significance
Familial renal amyloidosis
POEMS syndrome
Monoclonal gammopathy of renal significance