The several types of<unk> <unk>  vulgaris,<unk>  foliaceus, intraepidermal neutrophilic IgA dermatosis, and paraneoplastic<unk>  vary in severity. Skin lesions caused by<unk>  can lead to fatal infections, so treatment is extremely important.<unk>  vulgaris (PV - ICD-10 L10.0) is the most common form of the disorder and occurs when antibodies attack desmoglein 3. Sores often originate in the mouth, making eating difficult and uncomfortable. Although PV may occur at any age, it is most common among people between 40 and 60. It is more frequent among Ashkenazi Jews. Rarely, it is associated with myasthenia gravis. Nail disease may be the only finding and has prognostic value in management. *<unk>  foliaceus (PF) is the least severe of the three varieties. Desmoglein 1, the protein that is targeted by the autoantibodies, is enriched in the upper skin layers. PF is characterized by crusty sores that often begin on the scalp, and may move to the chest, back, and face. Mouth sores do not occur. This form is also frequent among Ashkenazi Jews. It is not as painful as PV, and is often misdiagnosed as dermatitis or eczema *Intraepidermal neutrophilic IgA dermatosis is characterized histologically by intraepidermal bullae with neutrophils, some eosinophils, and acantholysis. * The least common and most severe type of<unk>  is paraneoplastic<unk>  (PNP). This disorder is a complication of cancer, usually lymphoma or Castleman's disease. It may precede the diagnosis of the tumor. Painful sores appear on the mouth, lips, and the esophagus. In this variety of<unk> , the disease process often involves the lungs, causing bronchiolitis obliterans (constrictive bronchiolitis). Though much less frequent, it is still found the most in the Ashkenazi Jewish population. Complete removal of and/or cure of the tumor may improve the skin disease, but lung damage is generally irreversible. *Endemic<unk>  foliaceus includes fogo selvagem, the new variant of endemic<unk>  foliaceus in El Bagre, Colombia, and the Tunisian endemic<unk>  in North Africa. Hailey-Hailey disease, also called familial benign<unk> , is an inherited skin disease, not an autoimmune disease, so it is not considered part of the<unk>  group of diseases.
Pemphigus
Pellagra
Pemphigoid
Pemphigoid nodularis
Giant cell lichenoid dermatitis
Paraneoplastic pemphigus
Essential dermatitis
Drug-induced urticaria