There is no known definitive cure for<unk> . However, several drugs have proven to be effective in their treatment. Some of medication used to treat the symptoms are: * ACTH has shown improvements in symptoms but can result in an incomplete recovery with residual deficits. * Corticosteroids (such as prednisone or methylprednisolone) used at high dosages (500 mg - 2 g per day intravenously for a course of 3 to 5 days) can accelerate regression of symptoms. Subsequent very gradual tapering with pills generally follows. Most patients require high doses for months to years before tapering. * Intravenous Immunoglobulins (IVIg) are often used with varying results. * Several other immunosuppressive drugs, such as cyclophosphamide and azathioprine, may be helpful in some cases. * Chemotherapy for neuroblastoma may be effective, although data is contradictory and unconvincing at this point in time. * Rituximab has been used with encouraging results. * Other medications are used to treat symptoms without influencing the nature of the disease (symptomatic treatment): * Trazodone can be useful against irritability and sleep problems * Additional treatment options include plasmapheresis for severe, steroid-unresponsive relapses. The National Organization for Rare Disorders (NORD) recommends FLAIR therapy consisting of a three-agent protocol involving front-loaded high-dose ACTH, IVIg, and rituximab that was developed by the National Pediatric<unk>  Center, and has the best-documented outcomes. Almost all patients (80-90%) show improvement with this treatment and the relapse rate appears to be about 20%. A more detailed summary of current treatment options can be found at Treatment Options The following medications should probably be avoided: * Midazolam - Can cause irritability. * Melatonin - Is known to stimulate the immune system. * Also, see for more details
Opsoclonus myoclonus syndrome
Benign hereditary chorea
Parkinson-plus syndrome
Progressive supranuclear palsy
Sydenham's chorea
Huntington's disease-like syndrome
Post-encephalitic parkinsonism
Paroniria