Compared to other tricyclic antidepressants it produces significantly fewer cardiovascular, anticholinergic (like dry mouth or constipation), sedative and appetite-stimulating effects. A recent review found that it was amongst the antidepressants most prone to causing hepatotoxicity (liver damage), although the evidence to support this concern was of limited quality. Unlike other tricyclic antidepressants,<unk>  does not affect heart function. μ-Opioid receptor agonists can sometimes induce euphoria, as does<unk> , occasionally, at high doses, well above the normal therapeutic range.<unk>  can also cause severe withdrawal symptoms after prolonged use at high doses which should prompt extreme caution. By frequency Sources: ;Common (>1% frequency) * Headache (up to 18%) * Dizziness (up to 10%) * Insomnia/nightmares (up to 20%) * Drowsiness (up to 10%) * Dry mouth (up to 20%) * Constipation (up to 15%) * Nausea * Abdominal pain * Weight gain (~3%) * Agitation * Anxiety/irritability ;Uncommon (0.1-1% frequency) * Bitter taste * Flatulence * Gastralgia * Blurred vision * Muscle aches * Premature ventricular contractions * Micturition disturbances * Palpitations * Orthostatic hypotension * Hot flushes * Tremor ;Rare (<0.1% frequency) * Hepatitis * Hypomania * Euphoria * ECG changes * Pruritus/allergic-type skin reactions * Protracted muscle aches * General fatigue
Tianeptine
Droperidol
Galantamine
Rivastigmine
Cupiennin
Gliquidone
Tripelennamine
Bromperidol decanoate