It produces long-lasting effects, generally up to 16 hours in duration if taken orally and up to 12 hours if smoked or insufflated. Large doses have been reported anecdotally to last up to 36 hours. The effects are stimulant in nature, producing euphoria, increased attention, and increased cognition. Anecdotally, it has been reported to produce effects similar to nootropics. However, there is no research to support the claim that it is different or more effective than other psychostimulants in this respect. Moreover,<unk>  does not have the established safety profile of widely used clinical psychostimulants such as methylphenidate and dextroamphetamine. Time (h) Concentration of<unk>  in urine (µg/ml) 0-6<unk> 5 6-24 1.0 24-36 0.1 36-48 not detected There has been one reported death due to<unk>  and diazepam. Concentrations of<unk>  were: in blood 21.3 mg/L; in urine 12.3 mg/L. Diazepam concentration in blood was 0.8 mg/L. One experiment on rats has studied excretion of<unk>  in urine: "The concentration of trans-4-methylaminorex in rat urine following four injections of the trans-4S,5S isomer 5 mg/kg i.p each, at intervals of 12 h in 2 days, as measured quantitatively by GC/MS". Another study focused on pharmacokinetics and tissue distribution of the stereoisomers of<unk>  in rats. "Pulmonary hypertension has been associated with ingestion of the appetite suppressant aminorex. A similar compound,<unk> , was discovered on the property of three individuals with diagnoses of pulmonary hypertension."
4-Methylaminorex
Methylenedioxypyrovalerone
D-DOPA
3-Chloropropanoic acid
Beta-Hydroxy beta-methylbutyric acid
3-Indolepropionic acid
L-DOPA
Vanillylmandelic acid