Aging Age-related decline in the<unk>  tracts that make up the corpus callosum indicate the corpus callosum is involved in memory and executive function. Specifically, the posterior fibers of the corpus callosum are associated with episodic memory. Perceptual processing decline is also related to diminished integrity of occipital fibers of the corpus callosum. Evidence suggests that the genu of the corpus callosum does not contribute significantly to any one cognitive domain in the elderly. As fiber tract connectivity in the corpus callosum declines due to aging, compensatory mechanisms are found in other areas of the corpus callosum and frontal lobe. These compensatory mechanisms, increasing connectivity in other parts of the brain, may explain why elderly individuals still display executive function as a decline of connectivity is seen in regions of the corpus callosum. Older adults compared to younger adults show poorer performance in balance exercises and tests. A decline in white matter integrity of the corpus callosum in older individuals may explain declines in the ability to balance. Changes in the white matter integrity of the corpus callosum may also be related to cognitive and motor function decline as well. Decreased white matter integrity effects proper transmission and processing of sensorimotor information. White matter degeneration of the genu of the corpus callosum is also associated with gait, balance impairment, and the quality of postural control.
Commissural fiber
Geniculate fibers
Cerebrospinal fibers
Striatopallidal fibres
Projection fiber
Frontopontine fibers
Intrascleral plexus
Neurovascular bundle