<unk> s (HBOC) are cancer<unk> s that produce higher than normal levels of breast cancer,<unk>  cancer and additional cancers in genetically related families (either one individual had both, or several individuals in the pedigree had one or the other disease). It accounts for 90% of the hereditary cancers. The hereditary factors may be proven or suspected to cause the pattern of breast and<unk>  cancer occurrences in the family. The name HBOC may be misleading because it implies that this genetic susceptibility to cancer is mainly in women. In reality, both sexes have the same rates of gene mutations and HBOC can predispose to other cancers including prostate cancer and pancreatic cancer. For this reason, the term "King<unk> " has recently come into use. The new name references Mary-Claire King who identified the genes BRCA1 and BRCA2.
Hereditary breast–ovarian cancer syndrome
Estrogen insensitivity syndrome
Aromatase excess syndrome
Hereditary leiomyomatosis and renal cell cancer syndrome
Hereditary lobular breast cancer
Multiple endocrine neoplasia
Angelman syndrome
Multiple endocrine neoplasia type 1