<unk>  <unk>  is a glycoprotein (beta-globulin) produced by the Sertoli cells in the seminiferous tubules of the testis that binds specifically to testosterone (T), dihydrotestosterone (DHT), and 17-beta-estradiol. Because<unk>  binds to T and DHT, these hormones are made less lipophilic and become concentrated within the luminal fluid of the seminiferous tubules. The higher levels of these hormones enable spermatogenesis in the seminiferous tubules and sperm maturation in the epididymis.<unk>  has the same amino acid sequence as sex hormone-binding globulin (SHBG); the difference is the site of production and the addition of different sugar moieties.<unk>  contains 403 amino acids, resulting in a molecular weight of 44,533. Its gene is located on chromosome 17.<unk> ’s production is regulated under the influence of FSH on Sertoli cells, enhanced by insulin, retinol, and testosterone. The human<unk>  is not to be confused with a mouce secretoglobin of the same name, which is produced in the saliva.
Androgen-binding protein
Androgen prohormone
16α-Hydroxyestrone
17β-Aminoestrogen
3β-Androstanediol
3α-Androstanediol
8,9-Dehydroestrone
8,9-Dehydroestradiol