<unk>  describes the adverse effects of a substance that result either from a single exposure or from multiple exposures in a short period of time (usually less than 24 hours). To be described as<unk> , the adverse effects should occur within 14 days of the administration of the substance.<unk>  is distinguished from chronic toxicity, which describes the adverse health effects from repeated exposures, often at lower levels, to a substance over a longer time period (months or years). It is widely considered unethical to use humans as test subjects for<unk>  (or chronic) toxicity research. However, some information can be gained from investigating accidental human exposures (e.g., factory accidents). Otherwise, most<unk>  data comes from animal testing or, more recently, in vitro testing methods and inference from data on similar substances.
Acute toxicity
Chronic toxicity
Late effect
Progressive disease
Gateway drug effect
Toxicity
Spontaneous remission
Side Effect