The reason that anti-GFAP autoantibodies appear is currently unknown. There is the possibility that<unk>  is not pathogenic, but just an unspecific biomarker of several heterogeneous CNS inflammations. According to this hypothesis,<unk>  antibody itself does not induce pathological changes; it is only a biomarker for the process of immune inflammation
Autoimmune GFAP astrocytopathy
Anti-NMDA receptor encephalitis
Pantothenate kinase-associated neurodegeneration
Anti-Hu associated encephalitis
Anti-neurofascin demyelinating diseases
Glial tumor
Anti-VGKC-complex encephalitis
Hereditary CNS demyelinating disease