These include: * Delayed motor development * Hypotonia * Progressive neurodegeneration * Seizures
3-Hydroxyisobutyryl-CoA deacylase deficiency
Malonyl-CoA decarboxylase deficiency
3-Methylcrotonyl-CoA carboxylase deficiency
2-Methylbutyryl-CoA dehydrogenase deficiency
Pyruvate kinase deficiency
3-Hydroxy-3-methylglutaryl-CoA lyase deficiency
2,4 Dienoyl-CoA reductase deficiency
Succinyl-CoA:3-oxoacid CoA transferase deficiency