The genes mutated in AIS differ based on exposure to tobacco smoke. Non-smokers with AIS commonly have mutations in EGFR (a driver) or HER2 (an important oncogene), or a gene fusion with ALK or ROS1 as one of the elements.
Adenocarcinoma in situ of the lung
Epithelial-myoepithelial carcinoma of the lung
Salivary gland–like carcinoma of the lung
Minimally invasive adenocarcinoma of the lung
Sarcomatoid carcinoma of the lung
Mucinous cystadenocarcinoma of the lung
Adenocarcinoma of the lung
Pulmonary sclerosing pneumocytoma