<unk> , sold under the brand name Selanz SR among others, is a medication which reduces stomach acid. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. Effectiveness is similar to other proton pump inhibitors (PPIs). It is taken by mouth. Onset is over a few hours and effects last up to a couple of days. Common side effects include constipation, abdominal pain, and nausea. Serious side effects may include osteoporosis, low blood magnesium, Clostridium difficile infection, and pneumonia. Use in pregnancy and breastfeeding is of unclear safety. It works by blocking H+/K+-ATPase in the parietal cells of the stomach.<unk>  was patented in 1984 and came into medical use in 1992. It is available as a generic medication. In 2017, it was the 188th most commonly prescribed medication in the United States, with more than three million prescriptions.
Lansoprazole
Dexlansoprazole
Rabeprazole
Omeprazole
Tenatoprazole
Esomeprazole
Pantoprazole
Cimetidine