<unk>  is an overgrowth disorder caused by a rare genetic mosaicism. A genetic mutation during embryonic development gives rise to overgrowth in a subset of the individual's cells In 2011 researchers determined the cause of<unk> . In 26 of 29 patients who met strict clinical criteria for the disorder, Lindhurst et al. identified an activating mutation in AKT1 kinase in a mosaic state gene. Previous research had suggested the condition linked to PTEN on chromosome 10, while other research pointed to chromosome 16. Prior to the findings regarding AKT1 in 2011, other researchers expressed doubt regarding the involvement of PTEN or GPC3, which codes for glypican 3 and may play a role in regulating cell division and growth regulation.
Proteus syndrome
Gulf War syndrome
Toxic shock syndrome
Majeed syndrome
Proteus-like syndrome
Enterotoxemia
Crush syndrome
Multiple organ dysfunction syndrome