Dizziness and somnolence are the most frequent side effects. Fatigue, ataxia, peripheral edema (swelling of extremities), and nystagmus are also common.<unk>  is associated with a weight gain of 2.2 kg after 1.5 months of use. Case studies indicate that it may cause anorgasmia and erectile dysfunction, as well as myoclonus that disappear after discontinuing<unk>  or replacing it with other medication. DRESS, anaphylaxis, respiratory depression, and increased suicide behavior are the rare but serious side effects. Suicide The<unk>  label contains a warning of an increased risk of suicidal thoughts and behaviors. According to an insurance claims database study,<unk>  use is associated with about 40% increased risk of suicide, suicide attempt and violent death as compared with a reference anticonvulsant drug topiramate. The risk is increased for both bipolar disorder and epilepsy patients. Another study has shown an approximately doubled rate of suicide attempts and self-harm in patients with bipolar disorder who are taking<unk>  versus those taking lithium. Respiratory depression Serious breathing suppression, potentially fatal, may occur when<unk>  is taken together with opioids, benzodiazepines, or other depressants, or by people with underlying lung problems such as COPD.<unk>  and opioids are commonly prescribed or abused together, and research indicates that the breathing suppression they cause is additive. For example,<unk>  use before joint replacement or laparoscopic surgery increased the risk of respiratory depression by 30-60%. Withdrawal and dependence Withdrawal symptoms typically occur 1–2 days after abruptly stopping<unk> . Agitation, confusion and disorientation are the most frequently reported, followed by gastrointestinal complaints and sweating, and more rare tremor, tachycardia, hypertension and insomnia. In some cases, users experience withdrawal seizures. All these symptoms subside when<unk>  is re-instated. On its own,<unk>  appears to not have a substantial addictive power. In human and animal experiments, it shows limited to no rewarding effects. The vast majority of people abusing<unk>  are current or former abusers of opioids or sedatives. In these persons,<unk>  can boost the opioid "high" as well as decrease commonly experienced opioid-withdrawal symptoms such as anxiety.
Gabapentin
Pregabalin
Ibuprofen
Imagabalin
Naproxen
Meclofenamic acid
Oxcarbazepine
Paracetamol