Some conditions known to cause hypotonia include: Congenital – i.e.<unk>  a person is born with (including genetic disorders presenting within 6 months) * Genetic disorders are the most common cause * 22q13 deletion syndrome a.k.a. Phelan–McDermid syndrome * 3-Methylcrotonyl-CoA carboxylase deficiency * Achondroplasia * Aicardi syndrome * Autism spectrum disorders * Canavan<unk>  * Centronuclear myopathy (including myotubular myopathy) * Central core<unk>  * CHARGE syndrome * Cohen syndrome * Costello syndrome * Dejerine–Sottas<unk>  (HMSN<unk> <unk>  * Down syndrome a.k.a. trisomy 21 — most common * Ehlers–Danlos syndrome * Familial dysautonomia (Riley–Day syndrome) * FG syndrome * Fragile X syndrome * Griscelli syndrome<unk>  1 (Elejalde syndrome) * Holocarboxylase synthetase deficiency / Multiple carboxylase deficiency * Krabbe<unk>  * Leigh's<unk>  * Lesch–Nyhan syndrome * Marfan's syndrome * Menkes syndrome * Methylmalonic acidemia * Myotonic dystrophy * Niemann–Pick<unk>  * Nonketotic hyperglycinemia (NKH) or Glycine encephalopathy (GCE) * Noonan syndrome * Neurofibromatosis * Patau syndrome a.k.a. trisomy 13 *Pituitary dwarfism/growth hormone deficiency(in adults) * Prader–Willi syndrome * Rett syndrome * Septo-optic dysplasia (de Morsier syndrome) * Snyder–Robinson syndrome (SRS) * Spinal muscular atrophy (SMA) * Succinic semialdehyde dehydrogenase deficiency (SSADH) * Tay–Sachs<unk>  * Werdnig–Hoffmann syndrome – Spinal muscular atrophy with congenital degeneration of anterior horns of spinal cord. Autosomal recessive *Wiedemann–Steiner syndrome * Williams syndrome * Zellweger syndrome a.k.a. cerebrohepatorenal syndrome * Developmental disability * Cerebellar ataxia (congenital) * Sensory processing disorder * Developmental coordination disorder * Hypothyroidism (congenital) * Hypotonic cerebral palsy * Teratogenesis from in utero exposure to Benzodiazepines Acquired Acquired – i.e. onset occurs after birth * Genetic * Muscular dystrophy (including Myotonic dystrophy) – most common * Metachromatic leukodystrophy * Rett syndrome * Spinal muscular atrophy * Infections * Encephalitis * Guillain–Barré syndrome * Infant botulism * Meningitis * Poliomyelitis * Sepsis * Toxins * Infantile acrodynia (childhood mercury poisoning) * Autoimmunity disorders * Myasthenia gravis – most common * Abnormal vaccine reaction * Celiac<unk>  * Metabolic disorder * Hypervitaminosis * Kernicterus * Rickets * Neurological * Traumatic brain injury, such as the damage that is caused by shaken baby syndrome * Lower motor neuron lesions * Upper motor neuron lesions * Miscellaneous * Central nervous system dysfunction, including cerebellar lesions and cerebral palsy * Hypothyroidism * Sandifer syndrome * Neonatal benzodiazepine withdrawal syndrome in children born to mothers treated in late pregnancy with benzodiazepine medications
symptom of Glycogen storage disease type III
symptom of Coeliac disease
symptom of Glucose-6-phosphate dehydrogenase deficiency
symptom of Maroteaux–Lamy syndrome
symptom of Dubin–Johnson syndrome
symptom of Autoimmune hepatitis
symptom of Tropical sprue
symptoms of Rotor syndrome