Pharmacodynamics<unk>  selectively binds to both ERα and ERβ with high affinity. Its IC50 for ERα (1.5 nM) is similar to that of estradiol (4.8 nM) and is at least 10-fold higher than those of tamoxifen and raloxifene. Pharmacokinetics<unk>  has greatly improved oral bioavailability relative to tamoxifen and raloxifene, and this may also be involved in its greater potency.
Lasofoxifene
Bazedoxifene
Raloxifene
Ormeloxifene
Tamoxifen
Endoxifen
Anastrozole
Denosumab