<unk>  <unk>  is a genetic disorder characterized by deformities of the ears, eyes, cheekbones, and chin. The degree to which a person is affected, however, may vary from mild to severe. Complications may include breathing problems, problems seeing, cleft palate, and hearing loss. Those affected generally have normal intelligence.<unk>  is usually autosomal dominant. More than half the time it occurs as a result of a new mutation rather than being inherited from a person's parents. The involved genes may include<unk> , POLR1C, or POLR1D. Diagnosis is generally suspected based on symptoms and X-rays, and potentially confirmation by genetic testing.<unk>  is not curable. Symptoms may be managed with reconstructive surgery, hearing aids, speech therapy, and other assistive devices. Life expectancy is generally normal.<unk>  occurs in about one in 50,000 people. The syndrome is named after Edward<unk><unk> , an English surgeon and ophthalmologist, who described its essential traits in 1900.
Treacher Collins syndrome
Miller syndrome
ATR-16 syndrome
Hemifacial microsomia
ATR-X syndrome
Nager acrofacial dysostosis
LIG4 syndrome
Otocephaly