<unk>  is a<unk>  of the<unk>  the outer portion of the female genitals. It most commonly affects the labia majora. Less often, the labia minora, clitoris, or vaginal glands are affected. Symptoms include a lump, itchiness, changes in the skin, or bleeding from the<unk>  Risk factors include<unk>  intraepithelial neoplasia (VIN), HPV infection, genital warts, smoking, and many sexual partners. Most<unk> s are squamous cell<unk> s. Other types include adenocarcinoma, melanoma, sarcoma, and basal cell carcinoma. Diagnosis is suspected based on physical examination and confirmed by tissue biopsy. Routine screening is not recommended. Prevention may include HPV vaccination. Standard treatments may include surgery, radiation therapy, chemotherapy, and biologic therapy.<unk>  newly affected about 44,200 people and resulted in 15,200 deaths globally in 2018. In the United States, it newly occurred in about 6,070 people with 1,280 deaths a year. Onset is typically after the age of 45. The five-year survival rate for<unk>  is around 71% as of 2015. Outcomes, however, are affected by whether spread has occurred to lymph nodes.
Vulvar cancer
Lichen sclerosus
Genital ulcer
Hyperplasia
Amurca
Bartholin's cyst
Anal cancer
Atrophic vaginitis