Intracranial aneurysms may result from diseases acquired during life, or from genetic conditions. Hypertension, smoking, alcoholism, and obesity are associated with the development of brain aneurysms. Cocaine use has also been associated with the development of intracranial aneurysms. Other acquired associations with intracranial aneurysms include head trauma and infections. Genetic associations Coarctation of the aorta is also a known risk factor, as is arteriovenous malformation. Genetic conditions associated with connective tissue disease may also be associated with the development of aneurysms. This includes: * autosomal dominant polycystic kidney disease, * neurofibromatosis type I, * Marfan syndrome, * multiple endocrine neoplasia type I, * pseudoxanthoma elasticum, * hereditary<unk> c telangiectasia and * Ehlers-Danlos syndrome types II and IV. Specific genes have also had reported association with the development of intracranial aneurysms, including perlecan, elastin, collagen type 1 A2, endothelial nitric oxide synthase, endothelin receptor A and cyclin dependent kinase inhibitor. Recently, several genetic loci have been identified as relevant to the development of intracranial aneurysms. These include 1p34–36, 2p14–15, 7q11, 11q25, and 19q13.1–13.3.
medical cause of Subarachnoid hemorrhage
medical cause of Stroke
medical cause of Intracerebral hemorrhage
medical cause of Intracranial aneurysm
symptom of Intracranial aneurysm
symptom of Meningioma
medical cause of Vertebral artery dissection
symptom of Idiopathic intracranial hypertension