right<unk>  has an autosomal recessive inheritance pattern. The inheritance probabilities per birth are as follows: * If both parents are carriers: * 25% (1 in 4) children will have the disease * 50% (2 in 4) children will be carriers, but unaffected * 25% (1 in 4) children will be free of<unk>  – unaffected child that is not a carrier * If one parent is affected and one is free of<unk> : * 0% (0) children will have the disorder – only one parent is affected, other parent always gives normal gene * 100% (4 in 4) children will be carriers (but unaffected) * If one parent is a carrier and the other is free of<unk> : * 50% (2 in 4) children will be carriers (but unaffected) * 50% (2 in 4) children will be free of<unk>  – unaffected child that is not a carrier In addition to these frequencies there is a 'pseudo'-deficiency that affects 7–15% of the population. People with the pseudo deficiency do not have any<unk>  problems unless they also have affected status. With the current diagnostic tests, Pseudo-deficiency reports as low enzyme levels but sulfatide is processed normally so<unk>  symptoms do not exist. This phenomenon wreaks havoc with traditional approaches to Newborn Screening so new screening methods are being developed.
Metachromatic leukodystrophy
Multiple system atrophy
Leukodystrophy
Benign hereditary chorea
Stratton Parker syndrome
Spinocerebellar ataxia type 6
Infantile neuroaxonal dystrophy
Progressive supranuclear palsy