<unk>  occurs in all age groups but more often afflicts 20-40 year old individuals. Males and females are equally afflicted.<unk>  tumors, which may be tender or painful, typically present as rapidly growing solitary lesions that reach a final size (usually of 2-3 cm.) within a few weeks. They are located in the upper limbs (39–54% of cases), trunk (15–20% of cases), lower limbs (16–18% of cases), and head or neck area (20% of cases). (Involvement of the head or neck area is more commonly observed in children.) Rare cases off<unk>  have occurred in the: 1) joints of the knee (18 cases), shoulder (3 cases), hand (3 cases), elbow (2 cases), hip (1 case), ankle (1 case), and temporomandibular joint (1 case); or 2) peripheral nerves of the arm (i.e. ulnar nerve, 2 cases) or median nerve, 1 case), hip/lower limb (i.e. sciatic nerve, 1 case), and lumbar spine/pelvis/thigh (i.e. the obturator nerve, 1 case). Individual cases of<unk>  have been reported to occur in the lower female genital tract, bladder, prostate, tongue, and parotid gland. In some cases,<unk>  tumors have regressed after incisional biopsy, i.e. a biopsy that takes a small part of the diseased tissue. The cranial<unk>  variant of<unk>  occurs in the soft and hard cranial tissues of the outer layers of the skull. Patients with this variant are more commonly males than females and almost exclusively between 3 weeks and 6 years of age. They typically present with a tumor in areas of the head that lay directly over the temporal or parietal bones. Individual cases have been reported to occur in the lower jaw, frontonasal region, anterior nasal spine (i.e. nasal process of the maxilla), and the orbit (i.e. eye socket)-maxilla area. Characteristically, the tumor is rapidly enlarging, non-painful, rarely regressing without treatment, and potentially expanding into the skull's interior. In a review of 50 cases, the intravascular<unk>  variant of<unk>  occurred in individuals aged 6 months to 66 years (median age 27 years) with male and females being equally afflicted (52%:48%). Individuals with this variant commonly presented with a blood vessel-localized tumor of the head and neck area (34% of cases), lower extremity (32% of cases), upper extremity (20% of cases), or trunk (14% of cases). The tumor originates in the small blood vessels of the oral mucosa, eyes, lips, cheeks, tongues, and subcutaneous tissue of the extremities (78% of all cases). About 18% of cases involve major veins i.e. 5 cases involved the common femoral veins and one case each involved the femoral vein, common iliac vein, inferior vena cava, and subclavian vein. Cases involving the ascending aorta have also been reported. The presenting symptoms of these tumors were strictly dependent on their locations and impacts on the involved vasculature. Most cases involving superficial sites presented with a small (mean diameter of 1.5 cm), painless, slowly growing mass. However, tumors growing in deep tissues went unnoticed until they became large (e.g. 15 cm.) enough to obstruct blood flow: two cases involving the ascending aorta presented with the signs and symptoms of acute aortic dissection (e.g. severe pain, congestive heart failure, cardiac arrest, fainting , stroke, ischemic peripheral neuropathy, and/or paraplegia) while 9 cases involving large veins presented with acute swelling, pain, and tissue/organ dysfunctions in the areas drained by the involved veins.
Nodular fasciitis
Silicone granuloma
Pyogenic granuloma
Diffuse infantile fibromatosis
Acral necrosis
Aggressive fibromatosis
Juvenile hyaline fibromatosis
Villonodular synovitis