It is often a sign of myocardial ischemia, of which coronary insufficiency is a major cause. Other ischemic heart diseases causing<unk>  include: * Subendocardial ischemia or even infarction. Subendocardial means non full thickness ischemia. In contrast,<unk>  elevation is transmural (or full thickness) ischemia * Non Q-wave myocardial infarction * Reciprocal changes in acute Q-wave myocardial infarction (e.g.,<unk>  in leads I & aVL with acute inferior myocardial infarction) *<unk>  segment depression and T-wave changes may be seen in patients with unstable angina Depressed but upsloping<unk>  segment generally rules out ischemia as a cause. Also, it can be a normal variant or artifacts, such as: * Pseudo-ST-depression, which is a wandering baseline due to poor skin contact of the electrode * Physiologic J-junctional depression with sinus tachycardia * Hyperventilation<unk> ress ECG Other, non-ischemic, causes include: * Side effect of digoxin * Hypokalemia * Right or left ventricular hypertrophy * Intraventricular conduction abnormalities (e.g., right or left bundle branch block, WPW, etc.) * Hypothermia * Tachycardia * Reciprocal<unk>  elevation * Mitral valve prolapse * Central nervous system disease, such as<unk> roke Mnemonic A mnemonic can be used for some causes of<unk> , namely DEPRESSED<unk> : D - Drooping valve (mitral valve prolapse) E - Enlargement of the left ventricle P - Potassium loss R - Reciprocal<unk>  (e.g. inferior wall MI) E - Encephalon hemorrhage S - Subendocardial infarct S - Subendocardial ischemia E - Embolism (pulmonary) D - Dilated cardiomyopathy S - Shock T - Toxicity (digitalis/quinidine)
ST depression
DSM-IV codes
B symptoms
Ghon focus
Modic changes
Depressive
Double depression
Affective spectrum