The<unk>  of Triticeae<unk> s is important in several inflammatory diseases. It can be subdivided into innate responses (direct stimulation of immune system), class II mediated presentation (HLA DQ), class I mediated stimulation of killer cells, and antibody recognition. The responses to<unk>  proteins and polypeptide regions differs according to the type of<unk>  sensitivity. The response is also dependent on the genetic makeup of the human leukocyte antigen genes. In<unk>  sensitive enteropathy, there are 4 types of recognition, innate immunity (a form of cellular immunity priming), HLA-DQ, and antibody recognition of gliadin and transglutaminase. With idiopathic<unk>  sensitivity only antibody recognition to gliadin has been resolved. In wheat allergy, the response pathways are mediated through IgE against other wheat proteins and other forms of gliadin. Illustration of 2 alpha gliadins showing 2 proteolytically resistant sites, Top shows 6 T-cells sites in 33mer, and bottom shows innate immune peptide and two CXCR3 binding sites
Gluten immunochemistry
Alcian blue stain
Auramine phenol stain
Periodic acid–Schiff stain
Reticulin stain
Luxol fast blue stain
Jones' stain
Immunofluorescence