The course of HPS has been mild in rare instances of the disorder, however, the general prognosis is still considered to be poor.The disease can cause dysfunctions of the lungs, intestine, kidneys, and heart. The major complication of most forms of the disorder is pulmonary fibrosis, which typically exhibits in patients ages 40–50 years. This is a fatal complication seen in many forms of HPS, and is the usual cause of death from the disorder. HPS patients who develop pulmonary fibrosis typically have type 1 or type 4.
Hermansky–Pudlak syndrome
Keppen–Lubinsky syndrome
Sakati–Nyhan–Tisdale syndrome
Fox–Fordyce disease
Conradi–Hünermann syndrome
Kandinsky–Clérambault syndrome
Hallermann–Streiff syndrome
Shprintzen–Goldberg syndrome