The bacterium has an incubation period of 6 to 12 days, after which the affected individual experiences symptoms of conjunctivitis, or irritation similar to "pink eye". Blinding endemic<unk>  results from multiple episodes of reinfection that maintains the intense inflammation in the conjunctiva. Without reinfection, the inflammation gradually subsides. The conjunctival inflammation is called "active<unk> " and usually is seen in children, especially preschool children. It is characterized by white lumps in the undersurface of the upper eyelid (conjunctival follicles or lymphoid germinal centres) and by nonspecific inflammation and thickening often associated with papillae. Follicles may also appear at the junction of the cornea and the sclera (limbal follicles). Active<unk>  often can be irritating and have a watery discharge. Bacterial secondary infection may occur and cause a purulent discharge. The later structural changes of<unk>  are referred to as "cicatricial<unk> ". These include scarring in the eyelid (tarsal conjunctiva) that leads to distortion of the eyelid with buckling of the lid (tarsus) so the lashes rub on the eye (trichiasis). These lashes can lead to corneal opacities and scarring and then to blindness. Linear scars present in the sulcus subtarsalis are called Arlt's lines (named after Carl Ferdinand von Arlt). In addition, blood vessels and scar tissue can invade the upper cornea (pannus). Resolved limbal follicles may leave small gaps in the pannus (Herbert's pits). Most commonly, children with active<unk>  do not present with any symptoms, as the low-grade irritation and ocular discharge is just accepted as normal, but further symptoms may include: * Eye discharge * Swollen eyelids * Trichiasis (misdirected eyelashes) * Swelling of lymph nodes in front of the ears * Sensitivity to bright lights * Increased heart rate * Further ear, nose, and throat complications. The major complication or the most important one is corneal ulcer occurring due to rubbing by concentrations, or trichiasis with superimposed bacterial infection.
Trachoma
Nasal polyp
Orbital emphysema
Isthmicoma
Nasal vestibulitis
Acalvaria
Blepharitis
Tympanosclerosis