In syphilis, the<unk> is caused by a reaction to spirochaete bacteria in the tissue. It appears to be the human body's way to slow down the action of this bacteria; it is a unique immune response that develops in humans after the immune system fails to kill off syphilis.
Gumma 
Venom
Luts
Azumio
DermAtlas
Aura 
Aura
Crown 