B<unk>  Diffuse large B-cell lymphoma is the most common of the<unk> s. MeSH now classifies the phrase<unk> " under "Diffuse large B<unk>  lymphoma". Many other B-cell lymphomas feature large<unk> s: * Angiocentric lymphoma * Burkitt's lymphoma * Follicular<unk>  * Immunoblastic lymphoma * Intravascular<unk>  * Primary mediastinal B-cell lymphoma * T-cell–rich B-cell lymphoma * Primary splenic lymphoma (rare) * Primary central nervous system lymphomas, which are often diffuse large-B-cell lymphomas * Richter's transformation: Diffuse Large B-cell Variant *1) ABC subtype (common) *2) GCB subtype (rare) Activated B-Cell Diffuse Large B-Cell Lymphoma, or ABC-DLBCL, is believed to be caused by aberrant activation of a critical intracellular pathway. This intracellular signaling pathway involved in B-cell activation and proliferation stays constantly activated, driving lymphocytes to proliferate continuously. The inhibition of this pathway can be induced by a drug known as NEMO Binding Domain, or NBD, a peptide causing increased<unk>  death of malignant lymphocytes. T<unk>  Less commonly, a<unk>  may feature T<unk> s. Anaplastic<unk>  is an example of a<unk>  that involves T<unk> s. Of the large-cell T-cell lymphomas, it has the best prognosis.
Large-cell lymphoma
Mixed-cell lymphoma
Indolent lymphoma
Mature T-cell lymphoma
T-cell lymphoma
Aggressive lymphoma
B-cell lymphoma
Anaplastic large-cell lymphoma