<unk>  accumulates mainly in the heart, where it causes stiffness and often thickening of its walls, leading consequently to shortness of breath and intolerance to exercise, called diastolic dysfunction. Excessively slow heart rate can also occur, such as in sick sinus syndrome, with ensuing fatigue and dizziness.<unk> -type<unk>  deposition is also a common cause of carpal tunnel syndrome in elderly men, which may cause pain, tingling and loss of sensation in the hands. Some patients may develop carpal tunnel syndrome as an initial symptom of<unk> . There appears to be an increase in the risk for developing hematuria or blood in the urine due to urological lesions.
Wild-type transthyretin amyloid
Alpha-synuclein
Amyloid beta
Immunoreactive trypsinogen
Anti-gliadin antibodies
Keratic precipitate
Kamino bodies
Anchoring fibrils