The cause of<unk>  is stilll unclear, and there are several proposed mechanisms. A developmental field defect that occurs during blastogenesis is the current explanation of pathogenesis. The spleen derives from mesenchymal tissue and an inappropriate fusion can happen between the gonadal ridge during gut rotation, which occurs between weeks 5 and 8 of fetal life.<unk>  may result from an unknown teratogenic insult. The timing of this insult may correlate to the severity of associated defects. There is also postulation that fusion may occur due to adhesion after an inflammatory response or a lack of apoptosis between the structures. Siblings documented to have<unk>  and an accessory spleen provides additional evidence of a possible genetic component. Associated Conditions Additional congenital abnormalities are most often found associated with the continuous type of<unk> . These abnormalities include micrognathia, macroglossia, anal atresia, and pulmonary hypoplasia. The most commonly associated malformation is cryptorchidism. When limb abnormalities occur,<unk>  with Limb Defects is made as a separate diagnosis.<unk>  with Limb Defects is also of unknown cause but some literature suggests that that the condition may be related to Hanhart syndrome and facial femoral syndrome.<unk>  has also been identified in infants with Möbius syndrome and Poland syndrome.
Splenogonadal fusion
Regional odontodysplasia
Gonadal dysgenesis
Thyroid dysgenesis
Bone malrotation
Tooth fusion
Supernumerary kidney
XY gonadal dysgenesis