True<unk>  over years and decades can be a chronic condition affecting all aspects of a person's existence.<unk>  can lead to feelings of loneliness, fear of others, or negative self-esteem. Lack of consistent human contact can also cause conflict with the (peripheral) friends. The socially isolated person may occasionally talk to or cause problems with family members. In the case of mood-related<unk> , the individual may isolate during a depressive episode only to 'surface' when their mood improves. The individual may attempt to justify their reclusive or<unk> g behavior as enjoyable or comfortable. There can be an inner realization on the part of the individual that there is something wrong with their<unk> g responses which can lead to heightened anxiety. Relationships can be a struggle, as the individual may reconnect with others during a healthier mood only to return to an isolated state during a subsequent low or depressed mood.
Social isolation
Psychological resistance
Psychological resilience
Neglect
Social degeneration
Childhood trauma
Social rejection
Social stress