Genetic changes are related to the following<unk>  of<unk> . The system for classifying<unk> es is changing as researchers learn more about the genetic causes of these disorders. The clinical features of the<unk><unk>  and<unk> <unk> es vary among the disorders, but there is considerable overlap. Common signs and symptoms include problems with bone development that can result in short stature, enlarged joints, spinal curvature, and arthritis at a young age. For some people, bone changes can be seen only on X-ray images. Problems with vision and hearing, as well as a cleft palate with a small lower jaw, are common. Some individuals with these disorders have distinctive facial features such as protruding eyes and a flat nasal bridge.
Collagenopathy, types II and XI
Collagen disease
Acrokeratoelastoidosis of Costa
Fibromuscular dysplasia
Actinic elastosis
Mixed connective tissue disease
Adult polyglucosan body disease
Fibrin ring granuloma