<unk>  lesions are most commonly rapidly growing, soft tissue masses that may be ulcerating, bleeding, and/or painful. In a recent (2020) review of published cases, individuals presenting with PBD were typically middle-aged or elderly (range 1–88 years; median age 58 tears) males (~73% of cases). Only a few cases have been reported in pediatric cases. The PDL lesions occurred most commonly in lymph nodes (~23% of cases), the gastrointestinal tract (~18%), bone marrow (16%), and oral cavity (12%). Less frequently involved tissues include the skin, genitourinary tract, paranasal sinuses, lung, and bones. While cases of<unk>  may present as a primary oral, or, very rarely a skin or lymph node disease, most individuals present with a widespread stage III or IV disease which in ~40% of cases, is accompanied by systemic B-symptoms such as fever, night sweats, and recent weight loss. Some 48%-63% of<unk>  cases occur in individuals with HIV/AIDS; ~80% of these HIV/AIDS-afflicted individuals have EBV+ disease whereas only ~50% of<unk>  individuals that do not have HIV/AIDS are EBV-positive. Individuals who develop<unk>  following organ transplantation are EBV-positive in >85% of cases. Most post-transplant and HIV/AIDS patients have an extremely aggressive disease. However, patients whose major contributing factor to<unk> -development is EBV-positivity often present with, and continue to have, a significantly less aggressive disease than other patients with<unk> . It is similarly clear that, on average, elderly patients (>68 years) likewise present with, and continue to have, a significantly less aggressive disease.
Plasmablastic lymphoma
Diffuse large B-cell lymphoma
Mixed-cell lymphoma
Marginal zone B-cell lymphoma
Aggressive lymphoma
Gray zone lymphoma
Follicular lymphoma
Anaplastic large-cell lymphoma