Side effects of DHPA are similar to those of other progestins. Side effects of the combination of DHPA and estradiol enantate have reportedly included dysmenorrhea, breast tenderness, headache, edema, bloating, changes in libido, depression, anxiety, and injection site pain. The half-dose formulation of DHPA and estradiol enantate retains contraceptive effects but causes severe disruption of menstrual bleeding patterns. Likewise, the formulation of DHPA in combination with estradiol benzoate butyrate has been associated with poor control of menstrual bleeding.
Algestone acetophenide
Algestone acetonide
Promegestone
Androstanolone propionate
Methandriol propionate
High-dose estrogen
Ethinylestradiol sulfonate
Nomegestrol acetate