<unk> adiol plus the fatty acid valeric acid (valerate) equals<unk> adiol valerate, a C17β<unk>  of<unk> adiol and one of the most widely used<unk> s. Polyestradiol phosphate, a polymer of<unk> adiol phosphate, the C17β phosphoric acid<unk>  of<unk> adiol. It has on average of 13 repeat units.<unk> adiol<unk> s have an<unk>  moiety, usually a straight-chain fatty acid (e.g., valeric acid) or an aromatic fatty acid (e.g., benzoic acid), attached at the C3 and/or C17β positions of the<unk> oid nucleus. These alkoxy moieties are substituted in place of the hydroxyl groups present in the unesterified<unk> adiol molecule. Fatty acid<unk> s serve to increase the lipophilicity of<unk> adiol, increasing its solubility in fat. This causes them to form a depot with intramuscular or subcutaneous injection and gives them a long duration when administered by these routes. Some<unk> adiol<unk> s have other moieties instead of fatty acids as the<unk> s. Such<unk> s include sulfuric acid (as in<unk> adiol sulfate), sulfamic acid (as in<unk> adiol sulfamate), phosphoric acid (as in<unk> adiol phosphate), glucuronic acid (as in<unk> adiol glucuronide, and others (e.g.,<unk> amustine phosphate <unk> adiol 3-normustine 17β-phosphate)). These<unk> s are all hydrophilic, and have greater water solubility than<unk> adiol or fatty acid<unk> adiol<unk> s. Unlike fatty acid<unk> adiol<unk> s, water-soluble<unk> adiol<unk> s can be administered by intravenous injection. A few<unk> s are polymers. These include polyestradiol phosphate and polyestriol phosphate, which are polymers of<unk> adiol phosphate and<unk> iol phosphate monomers, respectively. The monomers are connected in both cases by phosphate groups via the C3 and C17β positions. Polyestradiol phosphate has an average polymer chain length of approximately 13 repeat units of<unk> adiol phosphate. That is, each polyestradiol phosphate molecule is a polymer consisting on average of 13<unk> adiol phosphate molecules bonded together. These polymeric<unk> s are hydrophilic and water-soluble. Upon intramuscular injection, they do not form a depot and instead are rapidly absorbed into the circulation. However, they are only slowly cleaved into monomers, and as a result, have a very long duration in the body even outlasting that of many longer-chain fatty-acid<unk> s.
Estrogen ester
Androgen ester
Progestogen ester
Estrogen conjugate
Xenoestrogen
Phytoestrogen
Tissue-selective estrogen complex
17β-Aminoestrogen