Four cardinal symptoms have sometimes been used as diagnostic criteria: * painful, fatty lipomas (benign fatty tumors) across anatomy * obesity, frequently in menopausal age * weakness and fatigue * emotional instability, depression, epilepsy, confusion and dementia. Other potential signs of the disease include: However, as it is unclear which symptoms are cardinal and which symptoms are minor signs in<unk> , it is unclear which should be used as diagnostic criteria. Researchers have proposed a 'minimal definition' based on symptoms most often part of<unk> : 1) Generalized overweight or obesity. 2) Chronic pain in the adipose tissue. The associated symptoms in<unk>  include obesity, fatty deposits, easy bruisability, sleep disturbances, impaired memory, depression, difficulty concentrating, anxiety, rapid heartbeat, shortness of breath, diabetes, bloating, constipation, fatigue, weakness, and joint and muscle aches. Regarding the associated symptoms in<unk> , only case reports have been published. No study involving medical examinations has been performed in a large group of patients.
Dercum's disease
Freiberg disease
Butcher's wart
Martorell's ulcer
Marjolin's ulcer
Coats' disease
Swaim's Panacea
Dieulafoy's lesion