<unk>  is generally a result of a de novo mutation in the gene PRRX1 on the long arm of chromosome 1. Autosomal trisomies, while prevalent in related conditions like cyclopia, are uncommon in<unk> . Development During early embryogenesis, many different organ systems begin development. Any disruption in these processes results in complex malformation that usually results in death. The first branchial arch will normally develop around the 23rd to 26th day of gestation, also known as Carnegie stage 10. Usually, failure of this will result in isolated agnathia, but<unk>  may occur in exceptional circumstances. After agenesis of the first branchial arch, no cure is possible.
Otocephaly
Möbius syndrome
Oxycephaly
Treacher Collins syndrome
Plagiocephaly
Goldenhar syndrome
Cebocephaly
Trigonocephaly