Anemia can result from significant<unk><unk> . When the body has sufficient<unk>  to meet its needs (functional<unk> , the remainder is stored for later use in cells, mostly in the bone marrow and liver. These stores are called ferritin complexes and are part of the human (and other animals)<unk>  metabolism systems. Men store about 3.5 g of<unk>  in their body, and women store about 2.5 g. Hepcidin is a peptide hormone produced in the liver that is responsible for regulating<unk>  levels in the body. Hepcidin decreases the amount of<unk>  available for erythropoesis (red blood cell production). Hepcidin binds to and induces the degradation of ferroportin, which is responsible for exporting<unk>  from cells and mobilizing it to the bloodstream. Conditions such as high levels of erythropoesis,<unk><unk>  and tissue hypoxia inhibit hepcidin expression. Whereas systemic infection or inflammation (especially involving the cytokine IL-6) or increased circulating<unk>  levels stimulate hepcidin expression.<unk>  is a mineral that is important in the formation of red blood cells in the body, particularly as a critical component of hemoglobin. About 70% of the<unk>  found in the body is bound to hemoglobin.<unk>  is primarily absorbed in the small intestine, in particular the duodenum and jejunum. Certain factors increase or decrease absorption of<unk> . For example, taking Vitamin C with a source of<unk>  is known to increase absorption. Some medications such as tetracyclines and antacids can decrease absorption of<unk> . After being absorbed in the small intestine,<unk>  travels through blood, bound to transferrin, and eventually ends up in the bone marrow, where it is involved in red blood cell formation. When red blood cells are degraded, the<unk>  is recycled by the body and stored. When the amount of<unk>  needed by the body exceeds the amount of<unk>  that is readily available, the body can use<unk>  stores (ferritin) for a period of time, and red blood cell formation continues normally. However, as these stores continue to be used,<unk>  is eventually depleted to the point that red blood cell formation is abnormal. Ultimately, anemia ensues, which by definition is a hemoglobin lab value below normal limits.
Iron-deficiency anemia
Lead poisoning
Iatrogenic anemia
Megaloblastic anemia
Hemoglobinemia
Nutritional anemia
Sideroblastic anemia
Myelophthisic anemia