<unk>  <unk>  automates the dosing of intravenous drugs during surgery. After the anesthetist sets the desired parameters in a computer and presses the start button, the system controls the<unk>  pump, while being monitored by the anesthetist.<unk>  is as safe and effective as manually<unk><unk> .<unk>  can be sub-classified according to the<unk> . The suffix 'e' as in<unk> e indicates that the<unk>  is the effect site, in most cases, the central nervous system or brain. Alternatively, the suffix 'p' denotes plasma, indicating that the device implementing the<unk>  model is to<unk>  the blood plasma. There are important differences in relation to the time taken for effect site equilibration. Studies have demonstrated the clinical safety of the effect-site<unk>  model. Popular<unk>  models exist for Propofol and the synthetic opioid Remifentanil. The models are based on pharmacokinetic studies and use software embedded in the<unk>  device. For propofol the Marsh and Schnider models are available and the Minto model is commonly used for remifentanil. In 2017, a project to emulate the<unk>  models in the python language was published on GitHub.
Target controlled infusion
Insulin shock therapy
Pulsatile insulin
Neurally adjusted ventilatory assist
Glucagon rescue
Intra-aortic balloon pump
Cardiopulmonary bypass
Intraoperative blood salvage