In general,<unk>  is caused by increased force applied across the<unk> , or a decrease in the resistance within the physis to shearing. Obesity is the by far the most significant risk factor. A study in Scotland looked at the weight of 600,000 infants, and followed them up to see who got<unk> . This study identified that obese children had an almost twenty times greater risk than thin children, with a 'dose-response'- so the greater the weight of the child, the greater the risk of<unk> . In 65 percent of cases of<unk> , the person is over the 95th percentile for weight. Endocrine diseases may also contribute (though are far less of a risk than obesity), such as hypothyroidism, hypopituitarism, and renal osteodystrophy. Sometimes no single cause accounts for<unk> , and several factors play a role in the development of a<unk>  i.e. both mechanical and endocrine (hormone-related) factors. Skeletal changes may also make someone at risk of<unk> , including<unk>  or acetabular retroversion, those these may simply be chronic skeletal manifestations of childhood obesity.
Slipped capital femoral epiphysis
Attenuated patella alta
Osteitis pubis
Retrocalcaneal bursitis
Luxating patella
Radial dysplasia
Multiple epiphyseal dysplasia
Calcaneal fracture