<unk>  inhibits the growth of fungi by specifically binding to ergosterol present in fungal cell membranes.<unk>  inhibits amino acid and glucose transport proteins leading to a loss of nutrient transport across the plasma membrane. While this binding is reversible, ergosterol binding acts as a universal mechanism of fungal inhibition, allowing<unk>  to act on diverse fungal pathogens from Saccharomyces yeast to Aspergillus moulds.<unk>  is unique amongst related antifungals specifically because it does not directly cause membrane permeabilization. Structurally-related antibiotics with similar binding properties are thought to produce hydrophilic channels that allow leakage of potassium and sodium ions from the cell.<unk>  has very low solubility in water; however,<unk>  is effective at very low levels. Its minimum inhibitory concentration is less than 10 ppm for most molds.
Natamycin
Capreomycin
Meropenem
Anisomycin
Erythromycin
Sideromycin
Clarithromycin
Paromomycin