The most commonly reported medication-related adverse reactions in people taking<unk>  without an estrogen in clinical trials of indications have included menstrual irregularities, headaches, migraines, nausea, breast tenderness, bloating, and weight gain. The use of progestins, in particular medroxyprogesterone acetate, in treating postmenopausal symptoms have been associated with increased risk of blood clots and breast cancer in a study carried out by the Women's Health Initiative. While the study did not involve<unk> , it is possible, but not certain, that it too increases these risks.<unk>  has been prescribed and used in over 10 million pregnancies worldwide. There have been no harmful effects exhibited due to the use of<unk>  while pregnant.<unk>  is safe to use during pregnancy only when prescribed and indicated by a medical practitioner. Studies have not shown any incidence of decreased fertility due to<unk>  at therapeutic dose. The Ames test found no evidence of any potential mutagenic or toxicity properties.
Dydrogesterone
Haloprogesterone
Hydroxyprogesterone acetate
Gestodene
Vinyltestosterone
Retroprogesterone
Ethinylestradiol
Algestone