Gross appearance of a<unk>  (left of image) and a slice of a normal kidney (right of image). Note the<unk> unded contour, the mahogany colour and the central scar. In gross appearance, the tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter). The main differential diagnosis of<unk>  is chromophobe renal cell carcinoma oncocytic variant, which like the<unk>  has eosinophilic cytoplasm, but has perinuclear clearing and, typically, some degree of nuclear atypia. Immunohistochemical profile *Cytokeratin AE1/AE3 + *Vimentin - *EMA + *CD10+/- *CK7 +/- parcellaire *CK20 - *CK19 - *AMACR (Racemase) - *S100 + *c-kit (CD117) + *Cadherin-E + *TFE3 - *CAM5.2 +
Renal oncocytoma
Renal medullary fibroma
Renal medullary carcinoma
Renal anaplastic sarcoma
Papillary renal cell carcinoma
Renal cell carcinoma
Renal cyst
Clear cell papillary renal cell carcinoma