Necrosis of the nose, the lips, and the fingers and residual bruising over both forearms in a person recovering from<unk>  that disseminated to the blood and the lungs. At one time, the person's entire body was bruised. After being transmitted via the bite of an infected flea, the Y. pestis bacteria become localized in an inflamed lymph node, where they begin to colonize and reproduce. Infected lymph nodes develop hemorrhages, which result in the death of tissue.Y. pestis bacilli can resist phagocytosis and even reproduce inside phagocytes and kill them. As the disease progresses, the lymph nodes can hemorrhage and become swollen and necrotic.<unk>  can progress to lethal septicemic<unk>  in some cases. The<unk>  is also known to spread to the lungs and become the disease known as the pneumonic<unk> . Symptoms appear 2–7 days after getting bitten and they include: * Chills * General ill feeling (malaise) * High fever > * Muscle cramps * Seizures * Smooth, painful lymph gland swelling called a bubo, commonly found in the groin, but may occur in the armpits or neck, most often near the site of the initial infection (bite or scratch) * Pain may occur in the area before the swelling appears * Gangrene of the extremities such as toes, fingers, lips, and tip of the nose. The best-known symptom of<unk>  is one or more infected, enlarged, and painful lymph nodes, known as buboes. Buboes associated with the<unk>  are commonly found in the armpits, upper femoral, groin, and neck region. Symptoms include heavy breathing, continuous vomiting of blood (hematemesis), aching limbs, coughing, and extreme pain caused by the decay or decomposition of the skin while the person is still alive. Additional symptoms include extreme fatigue, gastrointestinal problems, spleen inflammation, lenticulae (black dots scattered throughout the body), delirium, coma, organ failure, and death. Organ failure is a result of the bacteria infecting organs through the bloodstream. Other forms of the disease include septicemic<unk>  and pneumonic<unk>  in which the bacterium reproduces in the person's blood and lungs respectively.
Bubonic plague
Hittite plague
Sylvatic plague
Urban plague
Malaria
Scrub typhus
Pneumonic plague
Flying squirrel typhus