Hepatitis C virus <unk>  refer to the genetic variations that occurs in the hepatitis C virus. Hepatitis C is a contagious disease that primarily affects the liver, causing severe damage as the disease progresses. It is caused by the Hepatitis C virus, a small, enveloped RNA virus. The transmission of hepatitis C is through the contact with the blood of the infected person, for example by sharing the needles or by using non-sterile medical equipment.<unk>  is transmitted globally because of the high infection rate and is also associated with a high mortality rate. The World Health Organization indicates the 3.3% of the world population is infected by the<unk>  virus. Statistical records show that there are about 13 million<unk>  affected persons in Сhina, 3.5 million affected persons in the United States, and about 10 million people are affected by<unk>  in Pakistan. In all cases, the viral<unk> of the<unk>  stays the same, occasionally mutations do occur making the treatment more complex by targeting the changes in the<unk>  Hepatitis C virus<unk> is considered more common than the Hepatitis B virus infection contributing to more than a million cases annually and is considered one of the major reason for liver transplantation in United States. Some of the<unk>  may develop in people without symptoms leading to dangerous conditions like liver cirrhosis causing a permanent damage to liver and the unnoticed<unk>  conditions will affect brain, joints, blood vessels, bones, and kidneys. The complexity of the<unk>  made the treatment specific for the associated<unk>  The treatment for the<unk> also depends on the presence or absence of cirrhosis. There are six major<unk>  of hepatitis C virus which includes many subtypes. The<unk> can affect treatment of<unk>  infections. Recent studies show that<unk>  consist of 8<unk>  and 67 subtypes. All the<unk>  and subtypes affect the liver to the same extent of damage irrespective of the<unk> Among the common six<unk> ,<unk> 1 is the most prevalent form in the United States of America, covering around 70-90% of total infections. It is usually difficult to treat the people with<unk> 1.<unk> 2 and<unk> 3 are less common contributing to around 10-20%.<unk>  4 and 5 affect a large proportion of the population in undeveloped countries.<unk> 4 is the most common type of infections in Middle East and Africa, around 80% of total infections. About 15% of the people affected by<unk>  will get cured without medications, in which immune system plays a vital role in defeating the virus. Until recently, there were no specific vaccines available for treating hepatitis C virus<unk> .
HCV genotypes
HBsAg
Viral load
Child–Pugh score
Epidemiology of Hepatitis D
Hh blood group
Ferriman–Gallwey score
NS1 antigen test