Normal location of the appendix relative to other organs of the digestive system (anterior view). Cecum and appendix are visible at bottom left. Appendicitis Deep tenderness at<unk> , known as<unk> 's sign, is a sign of acute appendicitis. The clinical sign of referred pain in the epigastrium when pressure is applied is also known as Aaron's sign. Specific localization of tenderness to<unk>  indicates that inflammation is no longer limited to the lumen of the bowel (which localizes pain poorly), and is irritating the lining of the peritoneum at the place where the peritoneum comes into contact with the appendix. Tenderness at<unk>  suggests the evolution of acute appendicitis to a later stage, and thus, the increased likelihood of rupture. Other abdominal processes can also sometimes cause tenderness at<unk> . Thus, this sign is highly useful but neither necessary nor sufficient to make a diagnosis of acute appendicitis. The anatomical position of the appendix is highly variable (for example in retrocaecal appendix, an appendix behind the caecum), which also limits the use of this sign, as many cases of appendicitis do not cause<unk>  tenderness at<unk> . For most open appendectomies (as opposed to laparoscopic appendectomies), the incision is made at<unk> . Pseudoaneurysm A pseudoaneurysm in the aorta may be treated surgically, with an incision made between<unk>  and the lower intercostal spaces. Peritoneal dialysis<unk>  may be a useful site for insertion of a peritoneal dialysis catheter.
McBurney's point
Dandy's point
Kocher's point
Keen's point
Pimenta's point
Hampton's line
Schwalbe's line
Beau's lines