<unk>  is characterized by the complete absence of all four limbs. The<unk>  causes severe malformations of various parts of the body, including the face and head, heart, nervous system, skeleton, and genitalia. In many cases, the lungs are underdeveloped, which makes breathing difficult or impossible. Because children with<unk>  have such serious medical problems, most are stillborn or die shortly after birth.
Tetra-amelia syndrome
Fox–Fordyce disease
Pott disease
Kyrle disease
Sabinas brittle hair syndrome
Salla disease
Carey Fineman Ziter syndrome
Degos disease