<unk> , sold under the brand name Praluent, is a medication used as a second-line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment. It is a human monoclonal antibody that belongs to a novel class of anti-cholesterol drugs, known as PCSK9 inhibitors, and it was the first such agent to receive FDA approval. The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety. Common side effects include nasopharyngitis (cold), injection site reactions, and influenza. It was approved for medical use in the United States and in the European Union in 2015.
Alirocumab
Evolocumab
Olaratumab
Ustekinumab
Durvalumab
Emapalumab
Burosumab
Tralokinumab