Screening for hypothyroidism is performed in the newborn period in many countries, generally using TSH. This has led to the early identification of many<unk> s and thus the prevention of developmental delay. It is the most widely used newborn screening test worldwide. While TSH-based screening will identify the most common<unk> s, the addition of T4 testing is required to pick up the rarer central<unk> s of neonatal hypothyroidism. If T4 determination is included in the screening done at birth, this will identify<unk> s of congenital hypothyroidism of central origin in 1:16,000 to 1:160,000 children. Considering that these children usually have other pituitary hormone deficiencies, early identification of these<unk> s may prevent complications. In adults, widespread screening of the general population is a matter of debate. Some organizations (such as the United States Preventive Services Task Force) state that evidence is insufficient to support routine screening, while others (such as the American Thyroid Association) recommend either intermittent testing above a certain age in all sexes or only in women. Targeted screening may be appropriate in a number of situations where hypothyroidism is common: other autoimmune diseases, a strong family history of thyroid disease, those who have received radioiodine or other radiation therapy to the neck, those who have previously undergone thyroid surgery, those with an abnormal thyroid examination, those with psychiatric disorders, people taking amiodarone or lithium, and those with a number of health conditions (such as certain heart and skin conditions). Yearly thyroid function tests are recommended in people with Down syndrome, as they are at higher risk of thyroid disease. Guidelines for England and Wales from the National Institute for Health and Care Excellence (NICE) recommend testing for thyroid disease in people with type 1 diabetes and new-onset atrial fibrillation, and suggests testing in those with depression or unexplained anxiety (all ages), in children with abnormal growth, or unexplained change in behaviour or school performance. On diagnosis of autoimmune thyroid disease, NICE also recommends screening for celiac disease.
medical cause of Neonatal jaundice
complications of Hemolytic disease of the newborn
symptom of Neonatal jaundice
symptom of Dubin–Johnson syndrome
medical cause of Rhabdomyolysis
complications of Hepatitis
medical cause of Stillbirth
complications of Rubella