<unk>  is diagnosed by a kidney biopsy which reveals two key findings: a) histological evidence of Congo red staining material deposited in the interstitial, mesangial, glomerular, and/or vascular areas of the kidney and b) the identification of these deposits as containing mainly<unk>  as identified by proteomics methodologies. Kidney biopsy shows the presence of<unk> -based amyloid predominantly in the renal cortex interstitium, glomeruli, and arterioles.<unk>  can be distinguished from AL amyloidosis, the most common form of amyloidosis (~85% of total cases), by testing their blood for the presence of high levels of a clonal immunoglobulin light chain. If the patient tests negative for this light chain, positive Congo Red staining of the kidney biopsy strongly suggests<unk> .
LECT2 amyloidosis
AA amyloidosis
AL amyloidosis
Secondary systemic amyloidosis
Anti-AQP4 disease
Sarcoglycanopathy
Hyaluronidase deficiency
Monoclonal gammopathy