The<unk>  (abbreviated to NTI-TSS, or NTI-tension<unk>  system), is a type of occlusal splint that is claimed to prevent headache and migraine by reducing sleep bruxism (night-time tooth clenching and grinding). Sleep bruxism is purported to lead to a hyperactivity of the<unk>  nerve, often triggering typical migraine events. The hyperactivity of<unk>  neurons during trigemino-nociceptive stimulation is a proposed cause of migraine and is correlated with imaging of migraine sufferers. The objective of the NTI-TSS is to relax the muscles involved in clenching and bruxing, thus supposedly diminishing the chances for migraines and<unk>  headaches to develop through the reduction in<unk>  stimulation normally caused by parafunctional activity. It is sometimes used for temporomandibular joint dysfunction (TMD). The NTI-TSS is a small transparent plastic device which is, in its most widely used form, worn over the front four teeth, of either arch, at night, and intended to prevent contact of the canines and molars. It is normally fitted by a dentist trained in the technique, and is constructed by a dental laboratory.
Nociceptive trigeminal inhibition tension suppression system
Cholinergic anti-inflammatory pathway
Parasympathetic nervous system
Neural pathway
Special somatic afferent fiber
Somatosensory system
Central pattern generator
Premovement neuronal activity