<unk> 1 is characterized by total lack of the movements of the fetus, and is detectable at 13th week of pregnancy. It is accompanied by oedema, small chin, small lungs, crooked joints and occasional skin webs of the neck and elbows. The fetus has characteristic pattern of malpositions recognizable even in severely macerated fetuses with club feet and hyperextension of the knees but the elbows and wrists showing flexion<unk> s. Neuropathological analysis shows lack of anterior horn motoneurons and severe atrophy of the ventral spinal cord. The skeletal muscles are severely hypoplastic.
Lethal congenital contracture syndrome
Spastic cerebral palsy
Two feet-one hand syndrome
Cernunnos deficiency
Cerebral palsy
Congenital muscular dystrophy
Norman–Roberts syndrome
Congenital distal spinal muscular atrophy