<unk>  acts on benzodiazepine allosteric sites that are part of the GABAA receptor/ion-channel complex and this results in an increased binding of the inhibitory neurotransmitter GABA to the GABAA receptor thereby producing inhibitory effects on the central nervous system and body similar to the effects of other benzodiazepines.<unk>  is anticonvulsant. There is preferential storage of<unk>  in some organs including the heart of the neonate. Absorption by any administered route and the risk of accumulation is significantly increased in the neonate. The withdrawal of<unk>  during pregnancy and breast feeding is recommended, as<unk>  rapidly crosses the placenta and also is excreted in breast milk.<unk>  also decreases prolactin release in rats. Benzodiazepines act via micromolar benzodiazepine binding sites as Ca2+ channel blockers and significantly inhibit depolarization-sensitive Calcium uptake in animal nerve terminal preparations.<unk>  inhibits acetylcholine release in mouse hippocampal synaptosomes in vivo. This has been found by measuring sodium-dependent high affinity choline uptake in vitro after pretreatment of the mice in vivo with<unk> . This may play a role in<unk> 's anticonvulsant properties.
Chlordiazepoxide
Clorazepate
Amobarbital
Phenobarbital
Heptobarbital
Ethyl loflazepate
Tianeptine
Methylphenobarbital