The diagnosis of<unk>  is usually based on its presentation in newborn or young infants and biopsy or fine needle aspirate analyses of the tumors' pathology. These analyses should show the presence of spindle-shaped cells bearing eosinophilic paranuclear inclusions consisting of actin and vimentin filaments, which, if necessary, can be confirmed by immunofluorescence staining of the filiments. Inclusions may not be evident in older lesions stained with hematoxylin and eosin but may be apparent when stained with other reagents such as the Masson's trichrome stain, phosphotungstic acid-haematoxylin stain, elastic Van Gieson's stain, or Lendrum's phloxine-tartrazine stain. Demonstration of these filaments is not necessary for a diagnosis of IMF if the clinical picture and other histological findings are consistent with the disorder. Findings of one or a few usually small lesions centered in the dermis of a digit consisting of spindle-shaped cells and expressing α-smooth muscle actin, desmin, and calponin proteins would support the diagnosis of<unk> . Infantile myofibromatosis (IMF) is, like<unk> , a disease in which benign tumors develop primarily in the fingers and toes of newborns and infants and consists of spindle-shaped cells in a collagen fibrous background.<unk>  was once regarded as a sub-type of infantile myofibromatosis. However, IMF tumors can be far more aggressinve than<unk>  lesions and consist of cells that do not have paranuclear inclusions. The World Health Organization (2020) classification includes IPF but not IMF as a tumor in the in the category of benign fibroblastic and myofibroblastic tumors.
Infantile digital fibromatosis
Plantar fibromatosis
Juvenile plantar dermatosis
Superficial acral fibromyxoma
Aggressive infantile fibromatosis
Juvenile hyaline fibromatosis
Subungual exostosis
Diffuse infantile fibromatosis