Mechanism of action<unk>  has a distinct mechanism of action, disrupting multiple aspects of bacterial cell membrane function. It inserts into the cell membrane in a phosphatidylglycerol-dependent fashion, where it then aggregates. The aggregation of<unk>  alters the curvature of the membrane, which creates holes that leak ions. This causes rapid depolarization, resulting in a loss of membrane potential leading to inhibition of protein, DNA, and RNA synthesis, which results in bacterial cell death. It has been proposed that the formation of spherical micelles by<unk>  may affect the mode of action.
Daptomycin
Teicoplanin
Resistin
Colistin
Linezolid
Vancomycin
Minocycline
Sarecycline