<unk>  <unk>  is a hypercoagulability (an increased tendency of the blood to clot) characterized by a lack of a response to<unk>  protein C (APC), which normally helps prevent blood from clotting excessively. This results in an increased risk of venous thrombosis (blood clots in veins), which resulting in medical conditions such as deep vein thrombosis (usually in the leg) and pulmonary embolism (in the lung, which can cause death). The most common cause of hereditary<unk><unk>  is factor V Leiden mutation.
Activated protein C resistance
Protein C deficiency
Factor VII deficiency
COAT platelet defect
Primary fibrinogenolysis
Factor XII deficiency
Factor XIII deficiency
Antithrombin III deficiency