<unk>  (AFST), also termed angiofibroma, not otherwise specified, is a recently recognized and rare disorder that was classified in the category of benign fibroblastic and myofibroblastic tumors by the World Health Organization in 2020. An AFST tumor is a neoplasm (i.e. growth of<unk>  that is not coordinated with the normal surrounding<unk>  and persists in growing even if the original trigger for growth is removed) that was first described by A. Mariño-Enríquez and C.D. Fletcher in 2012. AFST tumors typically occur in a leg but can occur in other locations; they develop in older children and adults including elderly individuals. AFSTs are slow-growing, often painless tumors composed primarily of spindle-shaped cells and a prominent vascular network. The spindle-shaped cells are benign tumor cells that in almost all cases have chromosome abnormalities that are thought to contribute to their abnormal development and/or growth. AFST tumors are commonly treated by surgical excision although in uncommon cases they recur at the site of their removal and require further surgical treatment. They do not metastasize to distant<unk> s and overall have a good prognosis.
Angiofibroma of soft tissue
Cellular angiofibroma
Juvenile hyaline fibromatosis
Lymphangioma
Lymphohemangioma
Peripheral ossifying fibroma
Cavernous hemangioma
Aponeurotic fibroma