Prognosis refers to how well a patient is expected to respond to treatment based on their individual characteristics at time of diagnosis. In<unk> , three characteristic areas have been identified as significant in the prognosis of patients: Characteristic Values indicating a more favorable prognosis Sex Male Age at diagnosis < 2 years old Other existing conditions Diagnosis of Noonan syndrome Without treatment, the survival 5 years? of children with<unk>  is approximately 5%. Only Hematopoietic Stem Cell Transplantation (HSCT), commonly referred to as a bone marrow or (umbilical) cord blood transplant, has been shown to be successful in curing a child of<unk> . With HSCT, recent research studies have found the survival rate to be approximately 50%. Relapse is a significant risk after HSCT for children with<unk> . It is the greatest cause of death in<unk>  children who have had stem cell transplants. Relapse rate has been recorded as high as 50%. Many children have been brought into remission after a second stem cell transplant. After bone marrow transplant, the relapse rate for children with<unk>  may be as high as 50%. Relapse often occurs within a few months after transplant and the risk of relapse drops considerably at the one-year point after transplant. A significant number of<unk>  patients do achieve complete remission and long-term cure after a second bone marrow transplant, so this additional therapy should always be considered for children who relapse.
Juvenile myelomonocytic leukemia
T-lymphoblastic leukemia/lymphoma
Acute megakaryoblastic leukemia
Acute myeloblastic leukemia with maturation
Hypodiploid acute lymphoblastic leukemia
B-cell prolymphocytic leukemia
T-cell prolymphocytic leukemia
Precursor B-cell lymphoblastic leukemia