<unk> es (plantar in right foot and medial in left foot) A<unk>  is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required,<unk> es are most often found on the feet and hands, but they may occur anywhere on the skin. Some degree of<unk> , such as on the bottom of the foot, is normal.<unk> es are generally not harmful and help prevent blisters, as well as offering protection. However, excessive formation may sometimes lead to other problems, such as a skin ulceration or infection, or cause the sufferer to try to offload the affected painful area, which can place excessive stress on the asymptomatic side. Rubbing that is too frequent or forceful will cause blisters, as opposed to<unk> es, to form.
Callus
Plantar wart
Serous gland
Wart
Ovary
Pus
Dermatome
Dermatome 