<unk>  (AMD) is characterized by the inhibition of growth of certain long bones such as the forearms and lower legs. This disease typically becomes apparent during the first years of life. Forearms, lower legs, hands and feet do not grow proportionally with the rest of the body. Over time, individuals can have a hard time fully extending their arms, rotating the arms inwards towards the body with palms facing down and rotating the arms outward with the palms facing upward. Abnormalities of cartilage and bone development may also cause the bones within the fingers, toes, hands and feet to become sufficiently shorter and broader. During early childhood, individuals may experience progressive, abnormal curvature of the spine. Common symptoms include: * Short stature * Progressive degeneration * Stiffness * Tenderness * Osteoarthritis * Abnormal bone shape Infants with AMD typically have a normal birth weight, but can have other characteristic facial abnormalities. * Macrocephayl * Frontal bossing * Occipital prominence * Slightly flattened midface * Abnormally small, pug nose
Acromesomelic dysplasia
Campomelic dysplasia
Hereditary coproporphyria
Langer mesomelic dysplasia
Rhizomelic chondrodysplasia punctata
Mondini dysplasia
Brill–Zinsser disease
Degos disease