<unk>  is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Symptoms include skin rashes, severe arthritis, and chronic meningitis leading to neurologic damage. It is one of the cryopyrin-associated periodic syndromes.<unk>  can result from a mutation in the CIAS1 gene (also known as NLRP3 gene), which helps control inflammation. Mutations in this gene also cause familial cold urticaria and Muckle–Wells syndrome.<unk>  has been successfully treated with the drug anakinra. This syndrome is also known as the Prieur–Griscelli syndrome as it was first described by these authors in 1981.
Neonatal-onset multisystem inflammatory disease
Neonatal toxic shock-like exanthematous disease
Neonatal meningitis
Neonatal sepsis
Shaken baby syndrome
Neonatal hepatitis
Neonatal hypocalcemia
Neonatal diabetes