A blood test can be performed to quantify total homocysteine concentration in the plasma, of which approximately 80% is generally protein-bound. Classification of<unk>  is defined with respect to serum concentration as follows: * Moderate: 15–30 nmol/mL (or μmol/L) * Intermediate: 30–100 nmol/mL * Severe: > 100 nmol/mL If total homocysteine concentration is not found to be elevated, but clinical suspicion is still high, an oral methionine loading challenge several hours prior to quantification of homocysteine concentration may be used to increased sensitivity for marginal abnormalities of homocysteine metabolism. Fasting for 10 hours is sometimes recommended prior to measurement of homocysteine levels, but this may not be necessary for diagnostic yield.
Hyperhomocysteinemia
Hypoprothrombinemia
Hyperprothrombinemia
Hypodysfibrinogenemia
Hypoplasminogenemia
Pseudothrombocytopenia
Dysfibrinogenemia
Hypolipoproteinemia