The caloric intake of children with SRS must be carefully controlled in order to provide the best opportunity for growth. If the child is unable to tolerate oral feeding, then enteral feeding may be used, such as the percutaneous endoscopic gastrostomy. In children with limb-length differences or scoliosis, physiotherapy can alleviate the problems caused by these symptoms. In more severe cases, surgery to lengthen limbs may be required. To prevent aggravating posture difficulties children with leg length differences may require a raise in their shoe. Growth hormone therapy is often prescribed as part of the treatment of SRS. The hormones are given by injection typically daily from the age of 2 years old through teenage years. It may be effective even when the patient does not have a growth hormone deficiency. Growth hormone therapy has been shown to increase the rate of growth in patients and consequently prompts 'catch up' growth. This may enable the child to begin their education at a normal height, improving their self-esteem and interaction with other children. Several studies have shown that growth hormone therapy significantly improves childhood growth and final adult height. There are some theories suggesting that the therapy also assists with muscular development and managing hypoglycemia.
Silver–Russell syndrome
Miller–Dieker syndrome
Meckel–Gruber syndrome
Laurence–Moon syndrome
Intestinal metabolic bromhidrosis syndrome
Miller syndrome
Nathalie syndrome
Halperin-Birk syndrome