The etiology of the condition is unknown. Possible but unproven infectious causes are Klebsiella, polyomaviridae, Epstein–Barr virus, parvovirus B19, and human herpesvirus 6. Jilin University researchers suggested in 2017 that monocytes recruited to inflammatory lesions could produce macrophage colony-stimulating factor, which leads to a complex signal transduction, which leads to the histiocytosis characteristic of Destombes-Rosai–Dorfman disease.
Rosai–Dorfman disease
Mowat–Wilson syndrome
Akureyri disease
Wilson–Mikity syndrome
Wilson's disease
BENTA disease
Batten disease
Keshan disease