<unk>  is a primary malignant lung tumor whose cells contain a characteristic abnormal configuration of DNA wherein the echinoderm microtubule-associated protein-like 4 <unk>  gene is fused to the anaplastic lymphoma kinase <unk>  gene. This abnormal gene fusion leads to the production of a protein <unk> -ALK) that appears, in many cases, to promote and maintain the malignant behavior of the<unk>  cells. The transforming<unk> -ALK fusion gene was first reported in non-small cell lung carcinoma (NSCLC) in 2007.
EML4-ALK positive lung cancer
Limited-stage small cell lung carcinoma
Salivary gland–like carcinoma of the lung
complications of Mesothelioma
Thymoma with immunodeficiency
Combined small-cell lung carcinoma
Waldenström macroglobulinemia
Atypical pulmonary carcinoid tumour