<unk> -like<unk> s (retinoic acid-inducible gene-I-like<unk> s,<unk> s) are a type of intracellular pattern recognition<unk>  involved in the recognition of viruses by the innate immune system.<unk> -I (retinoic-acid inducible gene or DDX58) is the best characterized<unk>  within the<unk>  <unk>  family. Together with MDA5 (melanoma differentiation-associated 5) and LGP2 (laboratory of genetics and physiology 2), this family of cytoplasmic pattern recognition<unk> s (PRRs) are sentinels for intracellular viral RNA that is a product of viral infection. The<unk><unk> s provide frontline defence against viral infections in most tissues.
RIG-I-like receptor
Fc receptor-like molecule
Fc receptor
Type I cytokine receptor
Type II cytokine receptor
IL-2 receptor
Xenobiotic-sensing receptor
Toll-like receptor 7