Dantrolene sodium, the only available medical treatment for<unk>  The current treatment of choice is the intravenous administration of dantrolene, the only known antidote, discontinuation of triggering agents, and supportive therapy directed at correcting hyperthermia, acidosis, and organ dysfunction. Treatment must be instituted rapidly on clinical suspicion of the onset of<unk> . Dantrolene Dantrolene is a muscle relaxant that appears to work directly on the ryanodine receptor to prevent the release of calcium. After the widespread introduction of treatment with dantrolene, the mortality of<unk>  fell from 80% in the 1960s to less than 5%. Dantrolene remains the only drug known to be effective in the treatment of<unk> . The recommended dose of dantrolene is 2.5 mg/kg, repeated as necessary. It is recommended that each hospital keeps a minimum stock of 36 dantrolene vials (720 mg), sufficient for four doses in a 70-kg person. Training This is a mixed modality medical simulation of the treatment of<unk>  by anesthesia residents. The residents are managing care, mixing dantrolene and utilizing a cognitive aid at the bedside. Fast recognition and treatment of<unk>  utilizes skills and procedures that are utilized with a low-frequency and high-risk. Conducting<unk>  crisis training for perioperative teams can identify system failures as well as improve response to these events. Simulation techniques to include the use of cognitive aids have also been shown to improve communication in clinical treatment of<unk> .
Malignant hyperthermia
Sepsis
Hypothermia
Serotonin syndrome
Hyperthermia
Neuroleptic malignant syndrome
Nitrogen narcosis
Anaphylaxis