Risk factors for an aneurysm include diabetes, obesity, hypertension, tobacco use, alcoholism, high cholesterol, copper deficiency, increasing age, and tertiary syphilis infection. Connective tissue disorders such as Loeys-Dietz syndrome, Marfan syndrome, and certain forms of Ehlers-Danlos syndrome are also associated with aneurysms. Aneurysms, dissections, and ruptures in individuals under 40 years of age are a major diagnostic criteria of the vascular form of Ehlers-Danlos syndrome (vEDS). Specific infective causes associated with aneurysm include: * Advanced syphilis infection resulting in syphilitic aortitis and an aortic aneurysm * Tuberculosis, causing Rasmussen's aneurysms * Brain infections, causing infectious intracranial aneurysms A minority of aneurysms are associated with genetic factors. Examples include: * Berry aneurysms of the anterior communicating artery of the circle of Willis, associated with autosomal dominant polycystic kidney<unk>  * Familial thoracic aortic aneurysms * Cirsoid aneurysms, secondary to congenital arteriovenous malformations
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