Everson and Cole offered as explanation for<unk>  regression from cancer:In many of the collected cases ... it must be acknowledged that the factors or mechanisms responsible for<unk>  regression are obscure or unknown in the light of present knowledge. However, in some of the cases, available knowledge permits one to infer that hormonal influences probably were important. ... In other cases, the protocols strongly suggest that an immune mechanism was responsible. Challis and Stam, even more at a loss, concluded in 1989, "In summary, we are left to conclude that, although a great number of interesting and unusual cases continue to be published annually, there is still little conclusive data that explains the occurrence of<unk>  regression." Apoptosis (programmed cell death) and angiogenesis (growth of new blood vessels) are sometimes discussed as possible causes of<unk>  regression. But both mechanisms need appropriate biochemical triggers and cannot initiate on their own. Indeed, in many cancer cells apoptosis is defective, and angiogenesis is activated, both of these effects being caused by mutations in cancer cells; cancer exists because both mechanisms are malfunctioning. There are several case reports of<unk>  regressions from cancer occurring after a fever brought on by infection, suggesting a possible causal connection. If this coincidence in time would be a causal connection, it should as well precipitate as prophylactic effect, i.e. feverish infections should lower the risk to develop cancer later. This could be confirmed by collecting epidemiological studies.
Spontaneous remission
Progressive disease
Biphasic disease
Resistant cancer
Recrudescence
Infodemic
Precancerous condition
Acute toxicity