It was at one-time, but is no longer distributed by the Center for Disease Control on a compassionate use basis as an investigational drug for the treatment of metronidazole-resistant amoebiasis. Amoebic infections Some examples of the use of<unk>  in the treatment of amoebic infections include: # In 1993, the successful treatment of cutaneous amebiasis in a 7-year-old girl with<unk>  and metronidazole in Mexico. # A double-blind study of oral<unk>  in the treatment of amoebiasis performed at St. Mary's Hospital, Catholic Medical College, Seoul, Republic of Korea in 1973-1974 showed<unk>  treatment was effective. A total of 60 patients were treated, 20 with<unk> , 20 with Tiberal, and 20 with metronidazole. One-fourth of the patients treated with<unk>  reported adverse reactions, compared to 20% with other drugs, but no patient discontinued therapy due to the reaction. In all three cases, the drug therapy resulted in clearance of the infection, defined as negative results through an O&P exam, in all but 1-2 patients. # A 1979 study of 27 patients treated with<unk>  and various other drugs suggested all drug combinations were successful at treating amoebic liver abscesses. # A 1986 in vitro study compared the effects of<unk> , metronidazole, ornidazole, and secnidazole on Entamoeba histolytica. Metronidazole was found to be most effective, and the other three drugs were of similar effectiveness. In other diseases A 2020 in-vitro study found<unk>  to be effective in malaria. A 1980 report described the use of<unk>  in treatment of herpes zoster, a condition which can produce painful neurological symptoms. The study involved 40 patients, all of whom were over 60, and compared<unk>  treatment to another drug. The study reported patients treated with<unk>  experienced relief of neuralgia with no changes in cardiovascular functions.<unk>  has been investigated as a treatment for Leishmania infection.
Dehydroemetine
Reboxetine
Vinpocetine
Dexmethylphenidate
Sertindole
Methylphenidate
Chloracyzine
Medifoxamine