Fluorosis :See main article Dental fluorosis. The use of<unk>  toothpaste (with concentrations of 1000 ppm and above) and<unk>  supplements in children below the age of six years, and especially within the first three years of life, is associated with a greater risk of dental fluorosis. However, the use of<unk>  supplements during the last six months of pregnancy has no significant impact on the incidence of fluorosis in children. It has also been estimated that optimal water<unk> tion for the prevention of dental caries increases the prevalence of dental fluorosis by 4 to 5%. The observed effects are mild to moderate, usually of minimal aesthetic concern. Other risks Reports have claimed that water<unk> tion can be linked to the development of osteoporosis and various cancers; however, a recent systematic review has found no evidence to support these claims.
Fluoride therapy
Targeted therapy
Monoclonal antibody therapy
Stereotactic radiation therapy
Carboxytherapy
Radionuclide therapy
Chemoradiotherapy
Radiation therapy