Generalized diagram of<unk> : (A) Typically, the activated effector protein begins a signaling cascade which leads to the eventual opening of the ion channel. (B) The GTP-bound α-subunit in some cases can directly activate the ion channel. (C) In other cases, the activated βγ-complex of the G protein may interact with the ion channel.<unk> s are a family of transmembrane ion channels in neurons and atrial myocytes that are directly gated by G proteins.
G protein-gated ion channel
Cyclic nucleotide–gated ion channel
Voltage-gated ion channel
G protein-coupled receptor kinase 3
Mechanosensitive channels
Neurotransmitter transporter
Norepinephrine transporter
Glutamate transporter