Effective disease-modifying treatments have not yet been found for any of the<unk>  disorders. Current treatment is supportive and focused on improving symptoms: Dystonia is common and can be managed with oral medications, and sometimes with deep-brain electrical stimulation. Later in many of the diseases, slowing and stopping of movement (known as parkinsonism) can become common. Removal of<unk> , using medications known as<unk> -chelators, has been tested in clinical trial but was not definitively shown to be effective.
Neurodegeneration with brain iron accumulation
Leukoencephalopathy with vanishing white matter
Leukoencephalopathy with neuroaxonal spheroids
Megalencephalic leukoencephalopathy with subcortical cysts
Variably protease-sensitive prionopathy
Chronic traumatic encephalopathy in sports
Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
Limbic-predominant age-related TDP-43 encephalopathy