In the European Union, the drug is contraindicated during pregnancy because mice and monkeys receiving very high doses of<unk>  have been observed to suffer miscarriages and other pregnancy problems. In the U.S., it may be used for pregnant women "if the potential benefit justifies the potential risk to the fetus".
Apremilast
Roxadustat
Roflumilast
Azelastine
Lifitegrast
Ciclopirox
Montelukast
Budesonide