<unk>  (UHS) is a rare structural anomaly of the<unk>  with a variable degree of effect. It is characterized by<unk>  that is silvery, dry, frizzy, wiry, and impossible to comb. It was first reported in the early 20th century. It typically becomes apparent between the ages of 3 months and 12 years. UHS has several names, including “pili trianguli et canaliculi,” “cheveux incoiffables,” and “spun-glass<unk> .” This disorder is believed to be autosomal recessive in most instances, but there are a few documented cases where multiple family members display the trait in an autosomal dominant fashion. Based on the current scientific studies related to the disorder, the three genes that have been causally linked to UHS are PADI3, TGM3, and TCHH. These genes encode proteins important for<unk>  shaft formation. Clinical symptoms of the disorder arise between 3 months and 12 years of age. The quantity of<unk>  on the head does not change, but<unk>  starts to grow more slowly and becomes increasingly<unk> .” To be clinically apparent, 50% of all scalp<unk>  shafts must be affected by UHS. This<unk>  only affects the<unk>  shaft of the scalp and does not influence<unk>  growth in terms of quantity, textural feel, or appearance on the rest of the body.
Uncombable hair syndrome
X-linked hypertrichosis
Dual-role transvestism
Prepubertal hypertrichosis
Adiposogenital dystrophy
Paraphrenia
Latrodectism
Panner disease