Pharmacodynamics Testosterone levels with no treatment and with various estrogens in men with prostate cancer. Determinations were made with an early radioimmunoassay (RIA). Source was Shearer et al. (1973).<unk>  is an estrogen, or an agonist of the estrogen receptors. It is inactive itself and acts as a prodrug of diethylstilbestrol. Similarly to diethylstilbestrol,<unk>  has powerful antigonadotropic effects and strongly suppresses testosterone levels in men. It decreases testosterone levels into the castrate range within 12 hours of the initiation of therapy.<unk>  may also act by other mechanisms, such as via direct cytotoxic effects in the prostate gland. Pharmacokinetics The pharmacokinetics of<unk>  have been studied.
Fosfestrol
Hexestrol
Gestodene
Benzestrol
Moxestrol
Dienestrol
Dimestrol
Goserelin