Adverse effects observed with<unk>  are class effects of endothelin receptor antagonists, and include : * liver enzyme abnormalities (increased ALT and AST) * headache * edema * constipation * nasal congestion * upper respiratory tract infection * dizziness * insomnia * flushing Because<unk>  inhibits metabolism of warfarin, a decreased dose of warfarin is needed when co-administered with<unk> . This is because warfarin acts to prevent blood from clotting, and if it remains unmetabolized, it can continue to thin the blood.
Sitaxentan
Bosentan
Macitentan
Ambrisentan
Darusentan
Vericiguat
Tafamidis
Riociguat