Laboratory rats are used in some<unk> . Research into the mental disorder of schizophrenia, involves multiple<unk>  models as a tool, including in the preclinical stage of drug development. Several models simulate schizophrenia defects. These fit into four basic categories: pharmacological models, developmental models, lesion models, and genetic models. Historically, pharmacological, or drug-induced models were the most widely used. These involve the manipulation of various neurotransmitter systems, including dopamine, glutamate, serotonin, and GABA. Lesion models, in which an area of an<unk> 's brain is damaged, arose from theories that schizophrenia involves neurodegeneration, and that problems during neurodevelopment cause the disease. Rodent models of schizophrenia mostly display symptoms analogous to the positive symptoms of schizophrenia, with some models also having symptoms similar to the negative symptoms.<unk> s used as models for schizophrenia include rats, mice, and primates.
Animal model of schizophrenia
Disease model of addiction
Animal model of autism
Treatments for PTSD
Psychological therapies for dementia
Comparison of bipolar disorder and schizophrenia
Evolutionary models of human drug use
Life-process model of addiction