This<unk>  may be suspected on clinical grounds. The diagnosis is established by sequencing the CREBBP gene. Differential diagnosis * Rubinstein-Taybi<unk>
Menke-Hennekam syndrome
Fryns-Aftimos syndrome
Grisel's syndrome
Teunissen–Cremers syndrome
Fitzsimmons–Guilbert syndrome
Nicolaides–Baraitser syndrome
Franceschetti–Klein syndrome
Townes–Brocks syndrome