The major dose-limiting side effect of<unk>  is nephrotoxicity (i.e., kidney damage). Other common side effects (occurring in >1% of people treated with the drug) include: * Nausea * Vomiting * Neutropenia * Hair loss * Weakness * Headache * Chills * Decreased intraocular pressure * Uveitis * Iritis Whereas uncommon side effects include: anaemia and elevated liver enzymes and rare side effects include: tachycardia and Fanconi syndrome. Probenecid (a uricosuric drug) and intravenous saline should always be administered with each<unk>  infusion to prevent this nephrotoxicity. Contraindications Hypersensitivity to<unk>  or probenecid (as probenecid needs to be given concurrently to avoid nephrotoxicity). Interactions It is known to interact with nephrotoxic agents (e.g. amphotericin B, foscarnet, IV aminoglycosides, IV pentamide, vancomycin, tacrolimus, non-steroid anti-inflammatory drugs, etc.) to increase their nephrotoxic potential. As it must be given concurrently with probenecid it is advised that drugs that are known to interact with probenecid (e.g. drugs that probenecid interferes with the renal tubular secretion of, such as paracetamol, aciclovir, aminosalicylic acid, etc.) are also withheld.
Cidofovir
Brincidofovir
Telbivudine
Sorivudine
Lamivudine
Daclatasvir
Valaciclovir
Letermovir