<unk>  is a rare, adult-onset and autosomal recessive genetic disorder which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of inclusion bodies, known as<unk>  bodies, within the cytoplasm of the cells in the heart, liver, muscle, and skin.<unk>  is also a neurodegenerative disease that causes impairment in the development of cerebral cortical neurons and is a glycogen metabolism disorder.<unk>  (LD) was described by the Spanish Neuropathologist Gonzalo Rodríguez<unk>  (1886-1971) in 1911, while directing the Neuropathology Section at the Government Hospital for Mental Insane (current NIH, USA) Gonzalo Rodríguez<unk>  was a disciple of Santiago Ramón y Cajal (Nobel laureate in Physiology or Medicine 1906) and one of the most brilliant exponents of the Cajal School or the Spanish Neurological School. Typically<unk>  is very rare in children, adolescents and adults worldwide. However,<unk>  has a higher incidence among children and adolescents with ancestry from regions where incestuous relationships are common, namely the Mediterranean (North Africa, Southern Europe), the Middle East, India, and Pakistan. Dogs can also have the condition. In canines,<unk>  can spontaneously occur in any breed, but the Miniature Wire Haired Dachshund, Bassett Hound, and the Beagle are predisposed to LD. Most human patients with this disease do not live past the age of twenty-five, and death within ten years of symptoms is usually inevitable. Late onset symptoms of this disease can begin at any age depending on the genes affected. At present, there is no cure for this disease but there are ways to deal with symptoms through treatments and medications.
Lafora disease
Batten disease
Farber disease
Akureyri disease
Leber congenital amaurosis
Bayoud disease
Spastic ataxia-corneal dystrophy syndrome
Degos disease