<unk> s or CNG channels are ion channels that function in response to the binding of<unk><unk> s. CNG channels are nonselective cation channels that are found in the membranes of various tissue and cell types, and are significant in sensory transduction as well as cellular development. Their function can be the result of a combination of the binding of<unk><unk> s (cGMP and cAMP) and either a depolarization or a hyperpolarization event. Initially discovered in the cells that make up the retina of the eye, CNG channels have been found in many different cell types across both the animal and the plant kingdoms. CNG channels have a very complex structure with various subunits and domains that play a critical role in their function. CNG channels are significant in the function of various sensory pathways including vision and olfaction, as well as in other key cellular functions such as hormone release and chemotaxis. CNG channels have also been found to exist in prokaryotes, including many spirochaeta, though their precise role in bacterial physiology remains unknown. An example of the role of<unk> s in sea urchin sperm chemotaxis.
Cyclic nucleotide–gated ion channel
Voltage-gated ion channel
G protein-gated ion channel
Mechanosensitive channels
Neurotransmitter transporter
Glutamate transporter
Norepinephrine transporter
Tropomyosin receptor kinase A