Common symptoms The incubation period, the time between the start of infection and when symptoms begin to show, is about 7–25 days, averaging 16–18 days. 20–40% of infections are asymptomatic or are restricted to mild respiratory symptoms, sometimes with a fever. Over the course of the disease, three distinct phases are recognized: prodromal, early acute, and established acute. The prodromal phase typically has non-specific, mild symptoms such as a low-grade fever, headache, malaise, muscle pain, loss of appetite, and sore throat. In the early acute phase, as the mumps virus spreads throughout the body, systemic symptoms emerge. Most commonly, parotitis occurs during this time period. During the established acute phase, orchitis, meningitis, and encephalitis may occur, and these conditions are responsible for the bulk of mumps morbidity. The parotid glands are salivary glands situated on the sides of the mouth in front of the ears. Inflammation of them, called parotitis, is the most common mumps symptom and occurs in about 90% of symptomatic<unk> s and 60–70% of total infections. During mumps parotitis, usually both the left and right parotid glands experience painful swelling, with unilateral swelling in a small percentage of<unk> s. Parotitis occurs 2–3 weeks after exposure to the virus, within two days of developing symptoms, and usually lasts 2–3 days, but it may last as long as a week or longer. In 90% of parotitis<unk> s, swelling on one side is delayed rather than both sides swelling in unison. The parotid duct, which is the opening that provides saliva from the parotid glands to the mouth, may become red, swollen, and filled with fluid. Parotitis is usually preceded by local tenderness and occasionally earache. Other salivary glands, namely the submandibular, and sublingual glands, may also swell. Inflammation of these glands is rarely the only symptom. Complications Outside of the salivary glands, inflammation of the testes, called orchitis, is the most common symptom infection. Pain, swelling, and warmness of a testis appear usually 1–2 weeks after the onset of parotitis but can occur up to six weeks later. During mumps orchitis, the scrotum is tender and inflamed. It occurs in 10–40% of pubertal and post-pubertal males who contract mumps. Usually, mumps orchitis affects only one testis but in 10–30% of<unk> s both are affected. Mumps orchitis is accompanied by inflammation of the epididymis, called epididymitis, about 85% of the time, typically occurring before orchitis. The onsent of mumps orchitis is associated with a high-grade fever, vomiting, headache, and malaise. In prepubertal males, orchitis is rare as symptoms are usually restricted to parotitis. A variety of other inflammatory conditions may also occur as a result of mumps virus infection, including: * Mastitis, inflammation of the breasts, in up to about 30% of post-pubertal women * Oophoritis, inflammation of an ovary, in 5–10% of post-pubertal women, which usually presents as pelvic pain * Aseptic meningitis, inflammation of the meninges, in 5–10% of<unk> s and 4–6% of those with parotitis, typically occurring 4–10 days after the onset of symptoms. Mumps meningitis can also occur up to one week before parotitis as well as in the absence of parotitis. It is commonly accompanied by fever, headache, vomiting, and neck stiffness. *<unk> , inflammation of the pancreas, in about 4% of<unk> s, which<unk> s severe pain and tenderness in the upper abdomen below the ribs * Encephalitis, inflammation of the brain, in less than 0.5% of<unk> s. People who experience mumps encephalitis typically experience a fever, altered consciousness, seizures, and weakness. Like meningitis, mumps encephalitis can occur in the absence of parotitis. * Meningoencephalitis, inflammation of the brain and its surrounding membranes. Mumps meningoencephalitis is commonly accompanied by fever 97% of the time, vomiting 94% of the time, and headache 88.8% of the time. * Nephritis, inflammation of the kidneys, which is rare because kidney involvement in mumps is usually benign but leads to presence of the virus in urine * Inflammation of the joints (arthritis), which may affect at least five joints (polyarthritis), multiple nerves in the peripheral nervous system (polyneuritis), pneumonia, gallblader without gallstones (acalculous cholecystitis), cornea and uveal tract (keratouveitis), thyroids (thyroiditis), liver (hepatitis), retina (retinitis), and corneal endothelium (corneal endothelitis), all of which are rare * Recurrent sialadenitis, inflammation of the salivary glands, which is frequent A relatively common complication is deafness, which occurs in about 4% of<unk> s. Mumps deafness is often accompanied by vestibular symptoms such as vertigo and repetitive, uncontrolled eye movements. Based on electrocardiographic abnormalities in the infected, MuV also likely infects cardiac tissue, but this is usually asymptomatic. Rarely, myocarditis and pericarditis can occur. Fluid buildup in the brain, called hydrocephalus, has also been observed. In the first trimester of pregnancy, mumps may increase the risk of miscarriage. Otherwise, mumps is not associated with birth defects. Other rare complications of infection include: paralysis, seizures, cranial nerve palsies, cerebellar ataxia, transverse myelitis, ascending polyradiculitis, a polio-like disease, arthropathy, autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, Guillain–Barré syndrome, post-infectious encephalitis encephalomyelitis, and hemophagocytic syndrome. At least one complication occurs in combination with the standard mumps symptoms in up to 42% of<unk> s. Mumps has also been connected to the onset of type 1 diabetes, and, relatedly, the mumps virus is able to infect and replicate in insulin-producing beta cells. Among children, seizures occur in about 20–30% of<unk> s involving the central nervous system.
medical cause of Pancreatitis
symptom of Gallbladder cancer
symptom of Pancreatic cancer
symptom of Primary biliary cholangitis
symptom of Liver cancer
symptoms of Primary biliary cholangitis
complications of Gallstone
medical cause of Ascites