<unk> , also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of permanent scar tissue. Repeated injuries, chronic inflammation and repair are susceptible to<unk>  where an accidental excessive accumulation of extracellular matrix components, such as the collagen is produced by fibroblasts, leading to the formation of a permanent fibrotic scar. In response to injury, this is called scarring, and if<unk>  arises from a single cell line, this is called a fibroma. Physiologically,<unk>  acts to deposit connective tissue, which can interfere with or totally inhibit the normal architecture and function of the underlying organ or tissue.<unk>  can be used to describe the pathological state of excess deposition of fibrous tissue, as well as the process of connective tissue deposition in healing. Defined by the pathological accumulation of extracellular matrix (ECM) proteins,<unk>  results in scarring and thickening of the affected it is in essence an exaggerated wound healing response which interferes with normal organ function.
Fibrosis
Infibulation
Sclerosis 
Steatosis
Calcification
Neovascularization
Hydrodilatation
Transflammation