<unk> , sold under the trade name Coartem among others, is a combination of the two medications<unk>  and<unk> . It is used to treat malaria caused by Plasmodium falciparum that is not treatable with chloroquine. It is not typically used to prevent malaria. It is taken by mouth. Common side effects include muscle and joint pains, fever, loss of appetite, and headache. Serious side effects include prolongation of the QT interval. While not well studied, it appears to be safe for use in pregnancy. The dose does not need changing in those with mild or moderate kidney or liver problems. The combination came into medical use in 1992. They were both developed in China. It is on the World Health Organization's List of Essential Medicines. It is not available as a generic medication.
Artemether/lumefantrine
Artesunate/amodiaquine
Artesunate/mefloquine
Piperaquine/dihydroartemisinin
Artesunate/pyronaridine
Nifurtimox/eflornithine
Avermectin
Artesunate