<unk>  is a disorder featuring lack in either the quantity or the function of<unk> –an iron-containing protein expressed primarily in neutrophil granules. There are two types of<unk> : primary/inherited and secondary/acquired. Lack of functional<unk>  leads to less efficient killing of intracellular pathogens, particularly Candida albicans, as well as less efficient production and release of neutrophil extracellular traps (NETs) from the neutrophils to trap and kill extracellular pathogens. Despite these characteristics, more than 95% of individuals with<unk>  experience no symptoms in their lifetime. For those who do experience symptoms, the most common symptom is frequent infections by Candida albicans. Individuals with<unk>  also experience higher rates of chronic inflammatory conditions.<unk>  is diagnosed using flow cytometry or cytochemical stains. There is no treatment for<unk>  itself. Rather, in the rare cases that individuals experience symptoms, these infections should be treated. This image demonstrates the role of<unk>  in both the tissue where infection occurs and in the lymph nodes. In<unk> ,<unk>  is absent, and these functions occur less efficiently or not at all.
Myeloperoxidase deficiency
MBL deficiency
Leukocyte adhesion deficiency
Adenosine deaminase deficiency
Adenosine deaminase 2 deficiency
Leukocyte adhesion molecule deficiency
Neutrophil-specific granule deficiency
Primary immunodeficiency