<unk>  acts by interfering with the metabolism of acetylcholine. It is a reversible inhibitor of acetylcholinesterase, the enzyme responsible for the breakdown of acetylcholine in the synaptic cleft of the neuromuscular junction. It indirectly stimulates both nicotinic and muscarinic acetylcholine receptors.<unk>  has an LD50 of 3 mg/kg in mice. Bioactivity<unk>  functions as an acetylcholinesterase inhibitor. Its mechanism is to prevent the hydrolysis of acetylcholine by acetylcholinesterase at the transmitted sites of acetylcholine. This inhibition enhances the effect of acetylcholine, making it useful for the treatment of cholinergic disorders and myasthenia gravis. More recently,<unk>  has been used to improve the memory of Alzheimer's patients due to its potent anticholinesterase activity. However, its drug form,<unk>  salicylate, has poor bioavailability.<unk>  also has a miotic function, causing pupillary constriction. It is useful in treating mydriasis.<unk>  also increases outflow of the aqueous humor in the eye, making it useful in the treatment of glaucoma.
Physostigmine
Neostigmine
Pyridostigmine
Fomepizole
Suxamethonium chloride
Atropine
Eptazocine
Isavuconazonium