A<unk>  is a<unk>  that does not heal in an orderly set of stages and in a predictable amount of time the way most<unk> s do;<unk> s that do not heal within three months are often considered chronic.<unk> s seem to be detained in one or more of the phases of<unk>  healing. For example,<unk> s often remain in the inflammatory stage for too long. To overcome that stage and jump-start the healing process a number of factors need to be addressed such as bacterial burden, necrotic tissue, and moisture balance of the whole<unk> . In acute<unk> s, there is a precise balance between production and degradation of molecules such as collagen; in<unk> s this balance is lost and degradation plays too large a role.<unk> s may never heal or may take years to do so. These<unk> s cause patients severe emotional and physical stress and create a significant financial burden on patients and the whole healthcare system. Acute and<unk> s are at opposite ends of a spectrum of<unk> -healing types that progress toward being healed at different rates.
Chronic wound
Burn scar contracture
Wound contracture
Implant failure
Cancer cluster
Postoperative wounds
Stab wound
Chronic limb threatening ischemia