<unk>  <unk> D), is a rare and slow-growing malignancy which occurs within the epithelium and accounts for 6.5% of all<unk> ’s<unk> . The clinical presentation of this<unk>  is similar to the characteristics of mammary<unk> ’s<unk>  (MPD). However, unlike MPD, which occurs in large lactiferous ducts and then extends into the epidermis,<unk> D originates in glandular regions rich in apocrine secretions outside the mammary glands.<unk> D incidence is increasing by 3.2% every year, affecting hormonally-targeted tissues such as the vulva and scrotum. In women, 81.3% of<unk> D cases are related to the vulva, while for men, 43.2% of the manifestations present at the scrotum. The<unk>  can be classified as being either primary or secondary depending on the presence or absence of associated malignancies.<unk> D presents with typical symptoms such as scaly, erythematous, eczematous lesions accompanied by itchiness. In addition to this, 10% of patients are often asymptomatic. As a consequence,<unk> D has high rates of misdiagnoses and delayed diagnoses. There are a variety of treatment options available, but most are unsuccessful. If caught early and treated, prognosis is generally good.
Extramammary Paget's disease
Acral lentiginous melanoma
Arsenical keratosis
Acral fibrokeratoma
Hydrocarbon keratosis
Seborrheic keratosis
Lentigo maligna melanoma
Actinic keratosis