Children with the<unk>  have a triad of hypoparathyroidism (with episodes of hypocalcemia, hypocalcemic tetany and hypocalcemic seizures), severe intellectual disability and dysmorphism. Typically, children with this syndrome are born low-birth-weight due to intrauterine growth retardation. At birth, there is dysmorphism, which is later typified into the features described below. The child is stunted, often with demonstrable growth hormone deficiency and has moderate to severe intellectual disability, mainly as a consequence of repeated seizures brought on by the low blood ionic calcium levels. The immuno-reactive parathormone levels are low to undetectable, with low calcium and high phosphate levels in the blood. Dysmorphism is most evident on the face, with the following features: * Long narrow face * Deep-set, small eyes * Beaked nose * Large, floppy ears * Small head (microcephaly) and * Thin lips with a long philtrum. Other features Other features include: * Stunting * Small hands and feet with long, tapering fingers and clinodactyly * Dental anomalies in the form of malalignment and malocclusion In another study of six patients, there were low levels of IGF-1 and markedly retarded bone age.
Sanjad-Sakati syndrome
Gómez–López-Hernández syndrome
Okamoto syndrome
Grisel's syndrome
Mungan syndrome
Naegeli–Franceschetti–Jadassohn syndrome
Senior–Løken syndrome
Pashayan syndrome