Studies have shown its uses to be oral contraception, lessening premenstrual dysphoric disorder (PMDD), and treatment of moderate acne in women over 14 years of age who choose an oral contraceptive for contraception. Five clinical trials were carried out for these labeled uses, “including a one-year contraceptive efficacy study, two 3-cycle studies in women with premenstrual dysphoric disorder (PMDD), and two 6-cycle studies in women with moderate acne.” The drug combination will also increase folate levels due to its extra ingredient,<unk>  calcium. This is equivalent to folic<unk>  0.4 mg and will help prevent neural tube defects in case of accidental pregnancy while taking, or shortly after stopping the drug. Dosage and use Each box, as supplied by the manufacturer, contains three blister packs of 28 tablets packaged in individual boxes. Each blister pack of 28 tablets contains 24 pink active pills containing<unk>  3 mg, ethinylestradiol 20 mcg, and levomefolate calcium 0.451 mg and four light orange inactive pills containing of levomefolate calcium 0.451 mg. One tablet is taken by mouth at the same time every day. The failure rate may increase when pills are missed or taken incorrectly. Single missed pills should be taken as soon as remembered. It is important to know that when experiencing stomach upset in the form of diarrhea or vomiting (within 3–4 hours of taking), backup contraception methods should be utilized to account for possible absorption failure.
Drospirenone/ethinylestradiol/levomefolic acid
Ethinylestradiol/drospirenone
Estradiol enantate/algestone acetophenide
Ethinylestradiol/norethisterone
Ethinylestradiol sulfonate/norethisterone acetate
Ethinylestradiol/cyproterone acetate
Conjugated estrogens/norgestrel
Ethinylestradiol/megestrol acetate