Signs and symptoms may include weight loss, fever, malaise, cough, skin and mucosal lesions, diarrhea, and peripheral neuropathy. Cardiac symptoms are also possible. In cases associated with PDGFRB and FGFR1 mutations, splenomegaly is common. Lymphadenopathy is also common with FGFR1 mutations. Infiltration of eosinophils causes organ damage.
Chronic eosinophilic leukemia
Acute eosinophilic leukemia
Tropical eosinophilia
Thymoma with immunodeficiency
Diffuse infiltrative lymphocytosis syndrome
Hemophagocytic lymphohistiocytosis
Mast cell leukemia
Hereditary pyropoikilocytosis