<unk> s are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. This drug class was first introduced in the 1990s. While effective at treating individual headaches, they do not provide preventive treatment and are not considered a cure. They are not effective for the treatment of tension–type headache, except in persons who also experience migraines.<unk> s do not relieve other kinds of pain. The drugs of this class act as agonists for serotonin 5-HT1B and 5-HT1D receptors at blood vessels and nerve endings in the brain. The first clinically available<unk>  was sumatriptan, which has been marketed since 1991.<unk> s have largely replaced ergotamines, an older class of medications used to relieve migraine and cluster headaches.
Triptan
Sumatriptan
Frovatriptan
Rizatriptan
Eletriptan
Almotriptan
Zolmitriptan
Naratriptan