The parts of the<unk>  are the midbrain, the pons, and the medulla oblongata, and sometimes the diencephalon. Midbrain Diagram showing the position of the colliculi. Superior shown in green and inferior in orange. View of midbrain showing covering tectum and tegmental floor The midbrain is further subdivided into three parts: tectum, tegmentum, and the ventral tegmental area. The tectum forms the ceiling. The tectum comprises the paired structure of the superior and inferior colliculi and is the dorsal covering of the cerebral aqueduct. The inferior colliculus is the principal midbrain nucleus of the auditory pathway and receives input from several peripheral<unk>  nuclei, as well as inputs from the auditory cortex. Its inferior brachium (arm-like process) reaches to the medial geniculate nucleus of the diencephalon. The superior colliculus is positioned above the inferior colliculus, and marks the rostral midbrain. It is involved in the special sense of vision and sends its superior brachium to the lateral geniculate body of the diencephalon. The tegmentum which forms the floor of the midbrain, is ventral to the cerebral aqueduct. Several nuclei, tracts, and the reticular formation are contained here. The ventral tegmental area (VTA) is composed of paired cerebral peduncles. These transmit axons of upper motor neurons. Midbrain nuclei The midbrain consists of: *Periaqueductal gray: The area of gray matter around the cerebral aqueduct, which contains various neurons involved in the pain desensitization pathway. Neurons synapse here and, when stimulated, cause activation of neurons in the nucleus raphe magnus, which then project down into the posterior grey column of the spinal cord and prevent pain sensation transmission. *Oculomotor nerve nucleus: This is the third cranial nerve nucleus. *Trochlear nerve nucleus: This is the fourth cranial nerve. *Red nucleus: This is a motor nucleus that sends a descending tract to the lower motor neurons. *Substantia nigra pars compacta: This is a concentration of neurons in the ventral portion of the midbrain that uses dopamine as its neurotransmitter and is involved in both motor function and emotion. Its dysfunction is implicated in Parkinson's disease. *Reticular formation: This is a large area in the midbrain that is involved in various important functions of the midbrain. In particular, it contains lower motor neurons, is involved in the pain desensitization pathway, is involved in the arousal and consciousness systems, and contains the locus coeruleus, which is involved in intensive alertness modulation and in autonomic reflexes. *Central tegmental tract: Directly anterior to the floor of the fourth ventricle, this is a pathway by which many tracts project up to the cortex and down to the spinal cord. *Ventral tegmental area: A dopaminergic nucleus, known as group A10 cells is located close to the midline on the floor of the midbrain. *Rostromedial tegmental nucleus: A GABAergic nucleus located adjacent to the ventral tegmental area. Midbrain - superior colliculus.Cross-section of the midbrain at the level of the superior colliculus Midbrain - inferior colliculus.Cross-section of the midbrain at the level of the inferior colliculus Pons The pons lies between the medulla oblongata and the midbrain. The pons is separated from the midbrain by the superior pontine sulcus, and from the medulla by the inferior pontine sulcus. It contains tracts that carry signals from the cerebrum to the medulla and to the cerebellum and also tracts that carry sensory signals to the thalamus. The pons is connected to the cerebellum by the cerebellar peduncles. The pons houses the respiratory pneumotaxic center and apneustic center that make up the pontine respiratory group in the respiratory center. The pons co-ordinates activities of the cerebellar hemispheres. The pons and medulla oblongata are parts of the hindbrain that form much of the<unk> . Pons - Middle.Cross-section of the middle pons (at the level of cranial nerve V) Pons - Inferior.Cross-section of the inferior pons (at the level of the facial genu) Medulla oblongata The medulla oblongata, often just referred to as the medulla, is the lower half of the<unk>  continuous with the spinal cord. Its upper part is continuous with the pons. The medulla contains the cardiac, dorsal and ventral respiratory groups, and vasomotor centres, dealing with heart rate, breathing and blood pressure. Another important medullary structure is the area postrema whose functions include the control of vomiting. Medulla - Rostral level cross section.Cross-section of the rostral (superior) medulla Medulla - Middle level cross section.Cross-section of the middle medulla Medulla - Inferior level cross section.Cross-section of the inferior medulla Appearance ;From the front The appearance of a cadaveric<unk>  from the front, with major parts labelled In the medial part of the medulla is the anterior median fissure. Moving laterally on each side are the medullary pyramids. The pyramids contain the fibers of the corticospinal tract (also called the pyramidal tract), or the upper motor neuronal axons as they head inferiorly to synapse on lower motor neuronal cell bodies within the anterior grey column of the spinal cord. The anterolateral sulcus is lateral to the pyramids. Emerging from the anterolateral sulci are the CN XII (hypoglossal nerve) rootlets. Lateral to these rootlets and the anterolateral sulci are the olives. The olives are swellings in the medulla containing underlying inferior nucleary nuclei (containing various nuclei and afferent fibers). Lateral (and dorsal) to the olives are the rootlets for CN IX (glossopharyngeal), CN X (vagus) and CN XI (accessory nerve). The pyramids end at the pontine medulla junction, noted most obviously by the large basal pons. From this junction, CN VI (abducens nerve), CN VII (facial nerve) and CN VIII (vestibulocochlear nerve) emerge. At the level of the midpons, CN V (the trigeminal nerve) emerges. Cranial nerve III (the oculomotor nerve) emerges ventrally from the midbrain, while the CN IV (the trochlear nerve) emerges out from the dorsal aspect of the midbrain. Between the two pyramids can be seen a decussation of fibers which marks the transition from the medulla to the spinal cord. The medulla is above the decussation and the spinal cord below. ;From behind The appearance of a cadaveric<unk>  from behind, with major parts labelled The most medial part of the medulla is the posterior median sulcus. Moving laterally on each side is the gracile fasciculus, and lateral to that is the cuneate fasciculus. Superior to each of these, and directly inferior to the obex, are the gracile and cuneate tubercles, respectively. Underlying these are their respective nuclei. The obex marks the end of the fourth ventricle and the beginning of the central canal. The posterior intermediate sulcus separates the gracile fasciculus from the cuneate fasciculus. Lateral to the cuneate fasciculus is the lateral funiculus. Superior to the obex is the floor of the fourth ventricle. In the floor of the fourth ventricle, various nuclei can be visualized by the small bumps that they make in the overlying tissue. In the midline and directly superior to the obex is the vagal trigone and superior to that it the hypoglossal trigone. Underlying each of these are motor nuclei for the respective cranial nerves. Superior to these trigones are fibers running laterally in both directions. These fibers are known collectively as the striae medullares. Continuing in a rostral direction, the large bumps are called the facial colliculi. Each facial colliculus, contrary to their names, do not contain the facial nerve nuclei. Instead, they have facial nerve axons traversing superficial to underlying abducens (CN VI) nuclei. Lateral to all these bumps previously discussed is an indented line, or sulcus that runs rostrally, and is known as the sulcus limitans. This separates the medial motor neurons from the lateral sensory neurons. Lateral to the sulcus limitans is the area of the vestibular system, which is involved in special sensation. Moving rostrally, the inferior, middle, and superior cerebellar peduncles are found connecting the midbrain to the cerebellum. Directly rostral to the superior cerebellar peduncle, there is the superior medullary velum and then the two trochlear nerves. This marks the end of the pons as the inferior colliculus is directly rostral and marks the caudal midbrain. Middle cerebellar peduncle is located inferior and lateral to the superior cerebellar peduncle, connecting pons to the cerebellum. Likewise, inferior cerebellar peduncle is found connecting the medulla oblongata to the cerebellum. Blood supply vertebral arteries, shown here. The main supply of blood to the<unk>  is provided by the basilar arteries and the vertebral arteries. Development The human<unk>  emerges from two of the three primary brain vesicles formed of the neural tube. The mesencephalon is the second of the three primary vesicles, and does not further differentiate into a secondary brain vesicle. This will become the midbrain. The third primary vesicle, the rhombencephalon (hindbrain) will further differentiate into two secondary vesicles, the metencephalon and the myelencephalon. The metencephalon will become the cerebellum and the pons. The more caudal myelencephalon will become the medulla.
Brainstem
Spinal cord
Forebrain
Retina
Hindbrain
Barrel cortex
Sensory cortex
Midbrain reticular formation