Initial screening tests for GTN include: * Internal pelvic exam: to check for lumps or anything unusual changes. *Ultrasound exam of the pelvis: Also called a sonogram, an ultrasound creates a picture of the internal organ. In a transvaginal ultrasound, an ultrasound wand is inserted into the vagina and directed at the uterus to take the pictures. * Blood chemistry studies: It can be done to check the levels of certain hormones and other substances that may be impacted by the presence of GTN. * Serum tumor marker test: For GTN, the blood is checked for the level of β-hCG, a hormone that is made by the body during pregnancy. β-hCG in the blood of a woman who is not pregnant may be a sign of GTN and also helpful tests to monitor a woman’s recovery during and after treatment. Placental side<unk>  tumor (PSTT) is differentiated by low β-hCG levels because it is a<unk> ic proliferation of intermediate<unk>  cells. * Urinalysis: A test to check the color of urine and its contents, such as sugar, protein, blood, bacteria, and the level of β-hCG. *Spinal tap: Cerebrospinal fluid is tested for high amounts of the hormone β-hCG if the GTN has spread to the brain or spinal cord. *Computed tomography (CT): A CT scan can be used to measure the tumor's size. *Chest x-ray: It may be done if the tumor has spread outside of the uterus. Tumor staging FIGO (International Federation of Gynecology and Obstetrics) 2000 Anatomical staging is commonly used to evaluate stage of GTN. Stage I - Disease confined to the uterus Stage II - GTN extends outside of the uterus, but is limited to the genital structures (adnexa, vagina, broad ligament) Stage III - GTN extends to the lungs, with or without known genital tract involvement Stage IV - All other metastatic sites
Trophoblastic neoplasm
Embryonal carcinoma
Embryoma
Germ cell tumor
Gastroblastoma
Mixed Müllerian tumor
Gestational choriocarcinoma
Embryonal rhabdomyosarcoma