The<unk> s block the transmission of electrical activity in invertebrate nerve and muscle cells mostly by enhancing the effects of glutamate at the glutamate-gated chloride channel that is specific to protostome invertebrates, with minor effects on gamma-aminobutyric acid receptors. This causes an influx of chloride ions into the cells, leading to hyperpolarisation and subsequent paralysis of invertebrate neuromuscular systems; comparable doses are not toxic for mammals because they do not possess protostome-specific glutamate-gated chloride channels.
Avermectin
Ivermectin
Praziquantel
Albendazole
Mebendazole
Artemether
Flubendazole
Pyrantel