On gastroscopy,<unk>  is seen as a multitude of small white raised plaques of 2 mm to 10 mm in size, which may be seen throughout the esophagus. They tend to occur on esophageal folds, and may be missed if the esophagus is not well distended with air. It may be seen on esophageal x-rays; it is not seen on standard esophograms, but can be seen with double-contrast studies. Biopsies of the lesions show hypertrophied stratified squamous mucosa with glycogen deposition in the mucosa. Clinically, mild<unk>  is a normal finding, and does not progress to esophageal cancer or to stricture. It is not related to leukoplakia, and is not dysplastic or premalignant. It was originally thought to be associated with gastroesophageal reflux disease (GERD), but the association is not entirely clear. One report also shows an association with celiac disease, but again, this has not shown been beyond that. Extensive<unk>  has been shown to be associated with Cowden's syndrome.
Glycogenic acanthosis
Hyperkeratinization
Hyperkeratosis
Parakeratosis
Glomerulation
Granular parakeratosis
Pseudopolyps
Moist desquamation