Breathing a Vein, a caricature of bloodletting by venesection by James Gillray, 1804<unk> , also referred to as<unk>  depletion theory, was a therapeutic method advocating for rigorous treatment of bloodletting, purging, and sweating to shock the body back to health after an illness caused by a humoral imbalance. Rising to the front of orthodox medical practice in the "Age of<unk> " (1780–1850), it fell out of favor in the mid-19th century as gentler treatments were shown to be more effective and the idea of palliative treatment began to develop.
Heroic medicine
Psychoactive drug
Addiction medicine
Alcohol 
Antimanic drugs
Topological drugs
Psychedelic drug
Antiprion drug