<unk>  arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These<unk> ous cells have the ability to invade other parts of the body. A number of types of<unk>  are known. The most common,<unk>  adenocarcinoma, accounts for about 90% of cases, and the term<unk> " is sometimes used to refer only to that type. These adenocarcinomas start within the part of the pancreas that makes digestive enzymes. Several other types of<unk> , which collectively represent the majority of the non-adenocarcinomas, can also arise from these cells. About 1–2% of cases of<unk>  are neuroendocrine tumors, which arise from the hormone-producing cells of the pancreas. These are generally less aggressive than<unk>  adenocarcinoma. Signs and symptoms of the most-common form of<unk>  may include yellow skin, abdominal or back pain, unexplained weight loss, light-colored stools, dark urine, and loss of appetite. Usually, no symptoms are seen in the disease's early stages, and symptoms that are specific enough to suggest<unk>  typically do not develop until the disease has reached an advanced stage. By the time of diagnosis,<unk>  has often spread to other parts of the body.<unk>  rarely occurs before the age of 40, and more than half of cases of<unk>  adenocarcinoma occur in those over 70. Risk factors for<unk>  include tobacco smoking, obesity, diabetes, and certain rare genetic conditions. About 25% of cases are linked to smoking, and 5–10% are linked to inherited genes.<unk>  is usually diagnosed by a combination of medical imaging techniques such as ultrasound or computed tomography, blood tests, and examination of tissue samples (biopsy). The disease is divided into stages, from early (stage I) to late (stage IV). Screening the general population has not been found to be effective. The risk of developing<unk>  is lower among nonsmokers, and people who maintain a healthy weight and limit their consumption of red or processed meat. Smokers' chances of developing the disease decrease if they stop smoking and almost return to that of the rest of the population after 20 years.<unk>  can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. Treatment options are partly based on the<unk>  stage. Surgery is the only treatment that can cure<unk>  adenocarcinoma, and may also be done to improve quality of life without the potential for cure. Pain management and medications to improve digestion are sometimes needed. Early palliative care is recommended even for those receiving treatment that aims for a cure. In 2015,<unk> s of all types resulted in 411,600 deaths globally.<unk>  is the fifth-most-common cause of death from<unk>  in the United Kingdom, and the third most-common in the United States. The disease occurs most often in the developed world, where about 70% of the new cases in 2012 originated.<unk>  adenocarcinoma typically has a very poor prognosis; after diagnosis, 25% of people survive one year and 5% live for five years. For<unk> s diagnosed early, the five-year survival rate rises to about 20%. Neuroendocrine<unk> s have better outcomes; at five years from diagnosis, 65% of those diagnosed are living, though survival considerably varies depending on the type of tumor.
Pancreatic cancer
Autoimmune pancreatitis
Liver cancer
Duodenal cancer
Gallbladder cancer
Periampullary cancer
Kang cancer
Small intestine cancer