<unk>  also spelled<unk>  thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. For cyanide poisoning it is often used after the medication<unk>  nitrite and typically only recommended for severe cases. It is either given by injection into a vein or applied to the skin. Side effects may include vomiting, joint pain, mood changes, psychosis, and ringing in the ears. Safety, however, has not been well studied. It is unclear if use in pregnancy is safe for the baby. Use at the same time in the same intravenous line as hydroxocobalamin is not recommended. In cyanide poisoning<unk>  nitrite creates methemoglobinemia which removes cyanide from mitochondria.<unk> then binds with cyanide creating the nontoxic thiocyanate.<unk> came into medical use for cyanide poisoning in the 1930s. It is on the World Health Organization's List of Essential Medicines. The cost in the United States per dose as of 2013 is about US$20 while together with<unk>  nitrite it costs US$110.
Sodium thiosulfate 
Potassium permanganate 
Methylene blue
Sucroferric oxyhydroxide
Disufenton sodium
Sodium oxybate
Potassium fluoride
Acetylcysteine