Intestinal disturbances are common, including loss of appetite, nausea, vomiting, and constipation. In rare cases, it has been associated with colonic necrosis. Changes in electrolyte blood levels such as hypomagnesemia, hypocalcemia, and hypokalemia may occur.<unk> s should not be used in people with obstructive bowel disease and in newborns with reduced gut motility. Intestinal injury A total of 58 cases of intestinal injury including necrosis of the colon have been reported with<unk>  as of 2013. Well more cases have been reported when used in combination with sorbitol and other cases have occurred when used alone. Interactions<unk> s can bind to various drugs within the digestive tract and thus lower their absorption and effectiveness. Common examples include lithium, thyroxine, and digitalis. In September 2017, the FDA recommended separating the dosing of<unk>  from any other oral medications by at least three hours to avoid any potential interactions.
Polystyrene sulfonate
Polymethylsiloxane polyhydrate
Alpha-Zearalenol
Oxycyte
Methyl cellulose
Dextran
Macrogol
Modified citrus pectin