DHPA, also known as 16α,17α-dihydroxyprogesterone<unk> , as well as 16α,17α-dihydroxypregn-4-ene-3,20-dione cyclic acetal with acetophenone or as (R)-16α,17-(1-phenylethylidene)dioxypregn-4-ene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. It is specifically a derivative of 17α-hydroxyprogesterone with an additional hydroxyl group at the C17α position, or of algestone (16α,17α-dihydroxyprogesterone), and with the two hydroxyl groups cyclized into an<unk>  moiety (a cyclic acetal with acetophenone). Analogues of DHPA include other 17α-hydroxyprogesterone derivatives such as algestone acetonide (dihydroxyprogesterone acetonide), chlormadinone acetate, cyproterone acetate, gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate, and segesterone acetate. Synthesis Chemical syntheses of DHPA have been published.
Algestone acetophenide
Algestone acetonide
Promegestone
Androstanolone propionate
Methandriol propionate
High-dose estrogen
Ethinylestradiol sulfonate
Nomegestrol acetate