Signs of<unk>  may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). Symptoms of the condition in women may consist of menstrual irregularities, amenorrhea, abnormal vaginal bleeding, and enlargement of the uterus and breasts. It may also present as isosexual precocity in children and as hypogonadism, gynecomastia, feminization, impotence, and loss of libido in males. If left untreated,<unk>  may increase the risk of estrogen-sensitive cancers such as breast cancer later in life.
Hyperestrogenism
Hypoestrogenism
Side effects of bicalutamide
Hyperandrogenism
Androgen deficiency
Progestin-induced virilization
Side effects of cyproterone acetate
Antiestrogen withdrawal response