The<unk>  <unk>  is the lowest<unk>  of an antibacterial agent required to kill a particular bacterium. It can be determined from broth dilution minimum inhibitory<unk>  (MIC) tests by subculturing to agar plates that do not contain the test agent. The<unk>  is identified by determining the lowest<unk>  of antibacterial agent that reduces the viability of the initial bacterial inoculum by ≥99.9%. The<unk>  is complementary to the MIC; whereas the MIC test demonstrates the lowest level of antimicrobial agent that inhibits growth, the<unk>  demonstrates the lowest level of antimicrobial agent that results in microbial death. This means that even if a particular MIC shows inhibition, plating the bacteria onto agar might still result in organism proliferation because the antimicrobial did not cause death. Antibacterial agents are usually regarded as<unk>  if the<unk>  is no more than four times the MIC. Because the<unk>  test uses colony-forming units as a proxy measure of bacterial viability, it can be confounded by antibacterial agents which cause aggregation of bacterial cells. Examples of antibacterial agents which do this include flavonoids and peptides.
Minimum bactericidal concentration
Fractional kill
Trough level
Minimal infective dose
Median lethal dose
Toxic equivalency factor
Strain pattern
Minimum alveolar concentration