<unk>  are found clinically in about 1% of the population but this increases to 3.4% in individuals with a family history of ODD. About two thirds to three quarters of clinical cases are bilateral. A necropsy study of 737 cases showed a 2.4% incidence with 2 out of 15 (13%) bilateral, perhaps indicating the insidious nature of many cases. An autosomal dominant inheritance pattern with incomplete penetrance and associated inherited dysplasia of the<unk>  disc and its blood supply is suspected. Males and females are affected at equal rates. Caucasians are the most susceptible ethnic group. Certain conditions have been associated with disc<unk>  such as retinitis pigmentosa, angioid streaks, Usher syndrome, Noonan syndrome and Alagille syndrome.<unk>  are not related to Bruch membrane<unk>  of the retina which have been associated with age-related macular degeneration.
Optic disc drusen
Macular hole
Macular hypoplasia
Optic disc pallor
Macular corneal dystrophy
Macular edema
Corneal neovascularization
Macular scarring