It used to be thought that cases of<unk>  progressed through grades 1-3 toward cancer in a linear fashion. However most<unk>  spontaneously regress. Left untreated, about 70% of<unk>  1 will regress within one year; 90% will regress within two years. About 50% of<unk>  2 cases will regress within 2 years without treatment. Progression to cervical carcinoma in situ (CIS) occurs in approximately 11% of<unk>  1 and 22% of<unk>  2 cases. Progression to invasive cancer occurs in approximately 1% of<unk>  1, 5% of<unk>  2, and at least 12% of<unk>  3 cases. Progression to cancer typically takes 15 years with a range of 3 to 40 years. Also, evidence suggests that cancer can occur without first detectably progressing through<unk>  grades and that a high-grade intraepithelial<unk>  can occur without first existing as a lower grade. Research suggests that treatment does not affect the chances of getting pregnant but it is associated with an increased risk of miscarriage in the second trimester.
Cervical intraepithelial neoplasia
Cervical polyp
Vaginal intraepithelial neoplasia
Endometrial intraepithelial neoplasia
Cervical cancer
Vaginal adenosis
Endometrial polyp
Vaginal cancer