<unk> , sold under the brand name Januvia among others, is an anti-diabetic medication used to treat type 2 diabetes. In the United Kingdom it is listed as less preferred than metformin or a sulfonylurea. It is taken by mouth. It is also available in the fixed-dose combination medication<unk> /metformin (Janumet, Janumet XR). Common side effects include headaches, swelling of the legs, and upper respiratory tract infections. Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint pain. Whether use in pregnancy or breastfeeding is safe is unclear. It is in the dipeptidyl peptidase-4 (DPP-4) inhibitor class and works by increasing the production of insulin and decreasing the production of glucagon by the pancreas.<unk>  was developed by Merck & Co. and approved for medical use in the United States in 2006. In 2019, it was the 88th most commonly prescribed medication in the United States, with more than 8million prescriptions.
Sitagliptin
Linagliptin
Vildagliptin
Saxagliptin
Liraglutide
Exenatide
Pioglitazone
Canagliflozin