Certain mutations in the MYLK gene are associated with thoracic aortic aneurysms or thoracic aortic dissections. This disease is caused by mutations affecting the gene MYLK. A disease characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. It is primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Telokin
Equilin
Reelin
Clathrin
Progerin
Retapamulin
Eribulin
Collectin