The combination of<unk>  with dairy, antacids, calcium supplements, iron products, laxatives containing magnesium, or bile acid sequestrants is not inherently dangerous, but any of these foods and supplements may decrease<unk> 's effectiveness. Breakfast was observed to reduce<unk>  absorption significantly. Absorption of tetracycline occurs in the stomach and the upper small intestine. Absorption of tetracyclines has been reported to be impaired by milk products, aluminum hydroxide gels, sodium bicarbonate, calcium and magnesium salts, laxatives containing magnesium and iron preparations. The mechanisms responsible for decreased absorption appear to be chelation and an increase in gastric pH. ... In view of these results, it is advisable to instruct the patients to take<unk>  on an empty stomach. Previously,<unk>  was believed to impair the effectiveness of many types of hormonal contraception due to CYP450 induction. Research has shown no significant loss of effectiveness in oral contraceptives while using most tetracycline antibiotics (including<unk> , although many physicians still recommend the use of barrier contraception for people taking the drug to prevent unwanted pregnancy.
Doxycycline
Oxytetracycline
Amikacin
Streptomycin
Eravacycline
Minocycline
Secnidazole
Sarecycline