<unk>  When mast cells undergo degranulation, the substances that are released can cause a number of symptoms that can vary over time and can range in intensity from mild to severe. Because mast cells play a role in allergic reactions, the symptoms of<unk>  often are similar to the symptoms of an allergic reaction. They may include, but are not limited to * Fatigue * Skin lesions (urticaria pigmentosa), itching, and dermatographic urticaria (skin writing) * "Darier's Sign", a reaction to stroking or scratching of urticaria lesions. * Abdominal discomfort * Nausea and vomiting * Diarrhea * Olfactive intolerance * Ear/nose/throat inflammation * Anaphylaxis (shock from allergic or immune causes) * Episodes of very low blood pressure (including shock) and faintness * Bone or muscle pain * Decreased bone density or increased bone density (osteoporosis or osteosclerosis) * Headache * Depression * Ocular discomfort * Increased stomach acid production causing peptic ulcers (increased stimulation of enterochromaffin cell and direct histamine stimulation on parietal cell) * Malabsorption (due to inactivation of pancreatic enzymes by increased acid) * Hepatosplenomegaly There are few qualitative studies about the effects of<unk>  on daily life. However, a Danish study from 2018 describes the multidimensional impact of the disease on everyday life.
Mastocytosis
Monocytosis
Plasmacytosis
Lymphocytosis
Neutropenia
Macrocytosis
Neuroacanthocytosis
Neutrophilia