<unk>  can cause side effects, including oily spotting, fecal incontinence, flatus with discharge and abdominal cramping. Additionally, a raise in blood pressure, dry mouth, constipation, headache, and insomnia have been reported. Malabsorption of fat soluble vitamins may develop as a result of the impaired absorption of fat, which is required for the transportation of these vitamins across the intestine to reach the blood. Since<unk>  are not absorbed in the intestine, and consequently not circulating in the blood, information about alternative side effects such as the modulation of the gastrointestinal tract is unobtainable. Generally, side effects can be controlled by reducing the consumption of dietary fats. Overall, orlistat has been considered to be safer than other anti-obesity drugs.
Lipase inhibitors
COX-2 inhibitor
Steroid ester
Bile acid sequestrant
Quinolone antibiotic
Protease inhibitor 
Antiplatelet drug
Prostaglandin inhibitors