<unk>  (Lasix) for injection<unk>  is primarily used for the treatment of edema, but also in some cases of hypertension (where there is also kidney or heart impairment). It is often viewed as a first-line agent in most people with edema caused by congestive heart failure because of its anti-vasoconstrictor and diuretic effects. Compared with<unk> , however, torasemide has demonstrated to show improvements to heart failure symptoms, possibly lowers the rates of rehospitalisation associated with heart failure and has no difference in risk of death. Torsemide may also be safer than<unk> .<unk>  is also used for liver cirrhosis, kidney impairment, nephrotic syndrome, in adjunct therapy for swelling of the brain or lungs where rapid diuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration. Kidney disease In chronic kidney diseases with hypoalbuminemia, it is used along with albumin to increase diuresis. It is also used along with albumin in nephrotic syndrome to reduce edema. Other information * It is mainly excreted by tubular secretion in the kidney. In kidney impairment, clearance is reduced, increasing the risk of adverse effects. Lower initial doses are recommended in older patients (to minimize side-effects) and high doses may be needed in kidney failure. It can also cause kidney damage; this is mainly by loss of excessive fluid (i.e. dehydration), and is usually reversible. *<unk>  acts within 1 hour of oral administration (after IV injection, the peak effect is within 30 minutes). Diuresis is usually complete within 6–8 hours of oral administration, but there is significant variation between individuals.
Furosemide
Amiloride
Bumetanide
Chlorothiazide
Cyclothiazide
Spironolactone
Torasemide
Tolvaptan