<unk>  is breast hypertrophy before puberty. This form of hypertrophy is an increase in breast tissue.<unk>  occurs in pre-pubescent females, under the age of 8, having a peak occurrence in the first two years of life. The breast development is usually bi-lateral: both breasts show development. In some cases development may be unilateral: one breast develops. Patterns of<unk>  There are four patterns of<unk>  development. Most patients have hypertrophy followed by complete loss of the excess breast tissue (51% of cases) or loss of most excess tissue, but some remains until puberty (36% of cases). Less commonly patients have ongoing patterns of<unk> : 9.7% suffer from a cyclic pattern where the size of the breast tissue varies over time, and 3.2% experience continual increase in tissue size. Associated Symptoms The main symptom of<unk>  is enlarged breast tissue in infants. estrogen's role in<unk> , also leads to increased bone age and growth in some cases. In<unk>  these secondary symptoms are minimal: bone age only varies from actual age by a few months and growth velocity only slightly varies from the norm. Diagnostic tests will distinguish these<unk>  secondary symptoms from the more severe bone aging and growth occurring in early CPP.
Premature thelarche
Panner disease
Prepubertal hypertrichosis
Microorchidism
Uncombable hair syndrome
Tricho–dento–osseous syndrome
Sexual maturation disorder
Adiposogenital dystrophy