LPF presents as an ill-defined, slow growing tumor mass located in or below the subcutaneous tissue (area of the skin below the dermis) of an extremity or, less commonly, the thigh, trunk, or head areas. Rare single cases of these tumors have been reported in occur in the heart and eye socket. These tumors are often painless but in some cases become painful when manipulated during examination. LPF tumors occur almost exclusively in children at birth (~18% of cases) up to age 8 years with most cases presenting before age 2 years; they are extremely rare in adults. The disorder has a 2:1 male predominance. LPD tumors are usually 5 cm. or smaller and obvious on physical examination. Uncommonly, LPF tumors present after they have invaded adjacent underlying structures such as blood vessels, nerves, and muscles although significant functional impairment of the invaded tissues is uncommon. Individuals have also presented with recurrences of these tumors at the site of surgery in up to 1/3 of all surgically treated cases.
Lipofibromatosis
Actinic elastosis
Phakomatosis
Fibromatosis
Pyogenic granuloma
Fibrin ring granuloma
Lipoblastomatosis
Universal angiomatosis