<unk> is a vasoconstrictor used to increase blood pressure in adults with septic or other distributive shock.<unk> is a naturally occurring hormone secreted as part of the renin-angiotensin system that results in powerful systemic vasoconstriction. The vasopressor effects of<unk>  have been studied since it was first isolated in the late 1930s. Vasopressors are defined as agents that combat vasodilatory shock by inducing peripheral vasoconstriction. Commonly used vasopressors include catecholamine (e.g., dopamine, norepinephrine, epinephrine) and non-catecholamine (e.g., vasopressin). but these agents are not always effective in reversing vasodilatory shock, and their use can be associated with significant side effects including limb ischemia and cardiac arrhythmia.<unk> is as a treatment option that can increase blood pressure and allow catecholamine dose reductions.<unk> must be administered as an intravenous infusion diluted in 0.9% sodium chloride prior to use. The recommended starting dosage of<unk> is 20 nanograms (ng)/kg/min via continuous intravenous infusion. Administration through a central venous line is recommended. Monitor blood pressure response and titrate<unk> every 5 minutes by increments of up to 15 ng/kg/min as needed to achieve or maintain target blood pressure.
Angiotensin II 
Endothelin
Prorenin
Adrenomedullin
Prostacyclin
Vasopressin 
Vasopressin
Endrin