<unk>  <unk>  is a severe bone disease (osteonecrosis) that affects the<unk> s (the maxilla and the mandible). Various forms of<unk>  have been described since 1861, and a number of causes have been suggested in the literature.<unk>  associated with bisphosphonate therapy, which is required by some cancer treatment regimens, has been identified and defined as a pathological entity (bisphosphonate-associated<unk>  since 2003. The possible risk from lower oral doses of bisphosphonates, taken by patients to prevent or treat osteoporosis, remains uncertain. Treatment options have been explored; however, severe cases of<unk>  still require surgical removal of the affected bone. A thorough history and assessment of pre-existing systemic problems and possible sites of dental infection are required to help prevent the condition, especially if bisphosphonate therapy is considered.
Osteonecrosis of the jaw
Osteomyelitis of the jaws
Alveolar osteitis
Acroosteolysis
Osteomyelitis
Osteoradionecrosis
Medication-related osteonecrosis of the jaw
Osteolysis