<unk>  <unk>  is an historical term for a condition in which necrotic and highly destructive lesions develop progressively in the middle of the face, principally the nose and palate. Many cases presented with ulcerations in or perforations of the palate.<unk>  was thought to be a manifestation of three or four different diseases: the well-characterized disease of<unk> tosis with polyangiitis, the ill-defined disorders of polymorphic reticulosis or<unk>  malignant reticulosis, and an incompletely defined form of non-Hodgkin's lymphoma. Subsequent studies found that the cells infiltrating the<unk>  tissues in cases of<unk>  that were not clearly diagnosed as<unk> tosis with polyangiitis were: a) infected by the Epstein-Barr virus and b) consisted of malignant lymphocytes, usually NK cells or, rarely, cytotoxic T cells. The disease is therefore now regarded as a NK/T cell malignancy, is grouped with other Epstein-Barr virus-associated lymphoproliferative diseases and is classified by the World Health Organization (2017 update) as a manifestation of the well-defined disease, extranodal NK/T-cell lymphoma, nasal type (ENKTCL-NT). ENKTCL-NT is a rare type of lymphoma that commonly involves the nasal cavity, oral cavity, and/or pharynx but less commonly can also involve the eye, larynx, lung, gastrointestinal tract, skin, and various other tissues. Patients presenting with highly localized<unk>  facial disease fit the historical definition of<unk> . These cases, unlike other cases ENKTCL-NT that have more widespread disease, often show no or relatively little progression of their disease over long periods of time. Since cases of<unk>  that were manifestations of<unk> tosis with polyangiitis, a vascular inflammatory but not malignant disease, the term<unk>  is considered confusing and obsolete.
Lethal midline granuloma
Paradental cyst
Omphalolith
Sclerema neonatorum
Romanus lesion
Grisi siknis
Brodie abscess
Keratocyst