+ Herpes shedding<unk> V-2 genital 15–25% of days<unk> V-1 oral 6–33% of days<unk> V-1 genital 5% of days<unk> V-2 oral 1% of days Herpes is contracted through direct contact with an active lesion or body fluid of an infected person. Herpes transmission occurs between discordant partners; a person with a history of infection <unk> V seropositive) can pass the virus to an<unk> V seronegative person.<unk>  virus 2 is typically contracted through direct skin-to-skin contact with an infected individual, but can also be contracted by exposure to infected saliva, semen, vaginal fluid, or the fluid from herpetic blisters. To infect a new individual,<unk> V travels through tiny breaks in the skin or mucous membranes in the mouth or genital areas. Even microscopic abrasions on mucous membranes are sufficient to allow viral entry.<unk> V asymptomatic shedding occurs at some time in most individuals infected with herpes. It can occur more than a week before or after a symptomatic recurrence in 50% of cases. Virus enters into susceptible cells by entry receptors such as nectin-1, HVEM and 3-O sulfated heparan sulfate. Infected people who show no visible symptoms may still shed and transmit viruses through their skin; asymptomatic shedding may represent the most common form of<unk> V-2 transmission. Asymptomatic shedding is more frequent within the first 12 months of acquiring<unk> V. Concurrent infection with HIV increases the frequency and duration of asymptomatic shedding. Some individuals may have much lower patterns of shedding, but evidence supporting this is not fully verified; no significant differences are seen in the frequency of asymptomatic shedding when comparing persons with one to 12 annual recurrences to those with no recurrences. Antibodies that develop following an initial infection with a type of<unk> V prevents reinfection with the same virus type—a person with a history of orofacial infection caused by<unk> V-1 cannot contract herpes whitlow or a genital infection caused by<unk> V-1. In a monogamous couple, a seronegative female runs a greater than 30% per year risk of contracting an<unk> V infection from a seropositive male partner. If an oral<unk> V-1 infection is contracted first, seroconversion will have occurred after 6 weeks to provide protective antibodies against a future genital<unk> V-1 infection.<unk>  is a double-stranded DNA virus.
Herpes simplex
Shingles
Lentigo simplex
Molluscum contagiosum
Herpes labialis
Herpes gladiatorum
Smallpox
Cowpox