The metabolism of NOMAC is dependent on CYP3A4, so inhibitors and inducers of this enzyme such as ketoconazole and rifampicin, respectively, as well as some anticonvulsants, may pose a clinically significant drug interaction with NOMAC. (For a list of CYP3A4 inhibitors and inducers, see here.)
Nomegestrol acetate
Algestone acetonide
Promegestone
Algestone
Gestodene
Ethinylestradiol sulfonate
Hydroxyprogesterone acetate
Algestone acetophenide