Although there is no definitive reporting on its incidence,<unk>  shows prevalence in children and young adults than in patients thirty years of age or older. Epidemiological data suggests that cold climate, outdoor occupation, and low body mass index are significant risk factors for developing<unk> . As expected,<unk>  would be more prevalent in women than in men due to differences in BMI. However, the incidence rate of<unk>  often decreases with increasing age, regardless of regional climate. It completely resolves in many women after menopause implying significant hormonal influences. Around 50% of patients with POTS experience<unk>  of their legs while standing still.
Acrocyanosis
Nail clubbing
Cyanosis
Maculopathy
Rhagades
Retinopathy
Hyperthecosis
Pathergy