<unk>  (BMDM) refers to<unk>  cells that are generated in a research laboratory from mammalian<unk><unk>  cells. BMDMs can differentiate into mature<unk> s in the presence of growth factors and other signaling molecules. Undifferentiated<unk><unk>  cells are cultured in the presence of<unk>  colony-stimulating factor (M-CSF; CSF-1). M-CSF is a cytokine and growth factor that is responsible for the proliferation and commitment of myeloid progenitors into monocytes (which then mature into<unk> s).<unk> s have a wide variety of functions in the body including phagocytosis of foreign invaders and other cellular debris, releasing cytokines to trigger immune responses, and antigen presentation. BMDMs provide a large homogenous population of<unk> s that play an increasingly important role in making<unk> -related research possible and financially feasible. __TOC__
Bone marrow-derived macrophage
Megakaryocyte–erythroid progenitor cell
Passenger leukocyte
Dendritic cell
Reactive lymphocyte
Monocyte
Respirocyte
Nonspecific immune cell