Deaths from<unk>  per million persons in 2012<unk>  is the most common autoimmune disorder of the central nervous system. As of 2010, the number of people with<unk>  was 2–2.5 million (approximately 30 per 100,000) globally, with rates varying widely in different regions. It is estimated to have resulted in 18,000 deaths that year. In Africa rates are less than 0.5 per 100,000, while they are 2.8 per 100,000 in South East Asia, 8.3 per 100,000 in the Americas, and 80 per 100,000 in Europe. Rates surpass 200 per 100,000 in certain populations of Northern European descent. The number of new cases that develop per year is about 2.5 per 100,000. Rates of<unk>  appear to be increasing; this, however, may be explained simply by better diagnosis. Studies on populational and geographical patterns have been common and have led to a number of theories about the cause.<unk>  usually appears in adults in their late twenties or early thirties but it can rarely start in childhood and after 50 years of age. The primary progressive subtype is more common in people in their fifties. Similarly to many autoimmune disorders, the disease is more common in women, and the trend may be increasing. As of 2008, globally it is about two times more common in women than in men. In children, it is even more common in females than males, while in people over fifty, it affects males and females almost equally.
Multiple sclerosis
Lhermitte's sign
Tumefactive multiple sclerosis
Essential tremor
Paraneoplastic cerebellar degeneration
Anti-Hu associated encephalitis
Malignant multiple sclerosis
Thoracic outlet syndrome