In larger case series, the mortality was 1.6% overall. In the group of patients who were unwell enough to require surgery, the mortality was 1.9%, with no deaths in those who could be treated conservatively. After an episode of<unk> , 80% of people develop hypopituitarism and require some form of hormone replacement therapy. The most common problem is growth hormone deficiency, which is often left untreated but may cause decreased muscle mass and strength, obesity and fatigue. 60–80% require hydrocortisone replacement (either permanently or when unwell), 50–60% need thyroid hormone replacement, and 60–80% of men require testosterone supplements. Finally, 10–25% develop diabetes insipidus, the inability to retain fluid in the kidneys due to a lack of the<unk>  antidiuretic hormone. This may be treated with the drug desmopressin, which can be applied as a nose spray or taken by mouth.
Pituitary apoplexy
Empty sella syndrome
Neuroleptic malignant syndrome
Oculogyric crisis
Watershed stroke
Exploding head syndrome
Oculocerebrorenal syndrome
Transient ischemic attack