<unk>  is relatively safe in acute overdose. Symptoms following an acute overdose of<unk>  may include drowsiness, confusion, maculopapular or erythematous rash, nausea, vomiting, dizziness, and diarrhea. In rare cases, hyponatremia, hyperkalemia, or hepatic coma may occur in individuals with severe liver disease. However, these adverse reactions are unlikely in the event of an acute overdose. Hyperkalemia can occur following an overdose of<unk> , and this is especially so in people with decreased kidney function.<unk>  has been studied at extremely high oral doses of up to 2,400 mg per day in clinical trials. Its oral median lethal dose (LD50) is more than 1,000 mg/kg in mice, rats, and rabbits. There is no<unk> ecific antidote for overdose of<unk> . Treatment may consist of induction of vomiting or stomach evacuation by gastric lavage. The treatment of<unk>  overdose is supportive, with the purpose of maintaining hydration, electrolyte balance, and vital functions.<unk>  should be discontinued in people with impaired kidney function or hyperkalemia.
Spironolactone
Chlorothiazide
Cyclothiazide
Amiloride
Hydrochlorothiazide
Furosemide
Torasemide
Bumetanide