<unk>  is the use of<unk>  for medical purposes.<unk>  supplements are recommended to prevent tooth decay in children older than six months in areas where the drinking water is low in<unk> . It is typically used as a liquid, pill, or paste by mouth. Where public water supplies are<unk> ted further<unk>  by mouth is typically not needed.<unk>  has also been used to treat a number of bone diseases. Relatively high ingestion of<unk>  by babies and children may result in white marks on the teeth known as fluorosis. Excessive ingestion by babies and children can also result in severe dental fluorosis, indicated by a brown or yellow coloring and weakness/brittleness of the teeth, or in severe cases, acute toxicity.<unk>  typically uses the sodium<unk>  form, though stannous<unk>  may also be used.<unk>  decreases breakdown of teeth by acids, promotes remineralisation, and decreases the activity of bacteria. It is believed to work primarily through direct contact with the teeth in the mouth after they have emerged from the gums.<unk>  came into use to prevent tooth decay in the 1940s.<unk>  is on the World Health Organization's List of Essential Medicines. In 2017, it was the 247th most commonly prescribed medication in the United States, with more than one million prescriptions.
Fluoride therapy
Targeted therapy
Monoclonal antibody therapy
Stereotactic radiation therapy
Carboxytherapy
Radionuclide therapy
Chemoradiotherapy
Radiation therapy