<unk>  (RD) is caused either by the loss of the gene ZMPSTE24, which encodes a protein responsible for the cleavage of farnesylated prelamin A into mature non-farnesylated lamin, or by a mutation in the LMNA gene. This results in the accumulation of farnesyl-prelamin A at the nuclear membrane. Mechanistically,<unk>  is somewhat similar to Hutchinson–Gilford progeria syndrome (HGPS), a disease where the last step in lamin processing is hindered by a mutation that causes the loss of the ZMPSTE24 cleavage site in the lamin A gene.
Restrictive dermopathy
Diabetic dermopathy
Poikiloderma vasculare atrophicans
Febrile neutrophilic dermatosis
Cutaneous lupus mucinosis
Drug eruption
Paraneoplastic acrokeratosis
Eosinophilic dermatosis