Symptoms like cataracts, deafness, or ataxia appear before age 40. Cerebellar ataxias appears around age 40. There is also paranoid psychosis and dementia. Which both occur when the patient reaches their fifties. Although paranoid psychosis which typically develops after age 50. Hearing impairments Hearing loss can appear around 40s to 50s. Hearing impairments can also appear as young as age 10 to 20. Severe hearing loss can occur around age 45. Visual symptoms Vision problems are one the earliest symptoms of<unk>  with cataracts usually appear before age 30. The development of cataracts can appear as early as age 20. The median age for visual symptoms is 27. Other symptoms Other symptoms include intention tremor, neurofibrillary tangles, spasticity, apathy, hyperorality, early dyscalculia, and stereotyped behavior. Cerebral amyloid angiopathy in this disorder is severe. CAA is present in all regions of the central nervous system.
Familial Danish dementia
Familial British dementia
CADASIL
Canavan disease
Synucleinopathy
Menkes disease
Familial amyloid polyneuropathy
Sandhoff disease