A<unk> <unk> (NTT) is a blood<unk> for diagnosis of infection with<unk> .<unk><unk>  are an indirect method in that they detect biomarkers that are released during cellular damage that occurs from the<unk>  spirochete. In contrast, treponemal<unk>  look for antibodies that are a direct result of the infection thus, anti-treponeme IgG, IgM and to a lesser degree IgA.<unk><unk>  are screening<unk> , very rapid and relatively simple, but need to be confirmed by treponemal<unk> . Centers for Disease Control and Prevention (CDC)-approved standard<unk>  include the VDRL<unk> (a slide<unk> , the rapid plasma reagin (RPR)<unk> (a card<unk> , the unheated serum reagin (USR)<unk>  and the toluidine red unheated serum<unk> (TRUST). These have mostly replaced the first<unk> <unk>  the Wassermann<unk>  __TOC__
Nontreponemal tests for syphilis
Treponema pallidum particle agglutination assay
Fluorescent treponemal antibody absorption test
Dermatoscopy
Skin biopsy
Viral load monitoring for HIV
Venereal Disease Research Laboratory test
Malaria culture