<unk>  <unk>  is an anomaly of the human immune system characterized by mildly elevated levels of white blood<unk> s (called leukocytosis), chronic, stable absolute<unk>  B-cell lymphocytosis, elevated<unk>  IgM and binucleated<unk> s. Although cases of non-smoking women or men have been reported, patients are predominantly young smoking women.
Persistent polyclonal B-cell lymphocytosis
Chronic active EBV infection
Monoclonal B-cell lymphocytosis
Persistent generalized lymphadenopathy
Lymphoid neoplasms with plasmablastic differentiation
Thymoma-associated multiorgan autoimmunity
Progressive transformation of germinal centres
Immunodeficiency with hyperimmunoglobulin M