The different manifestations of BHD are controlled in different ways. The fibrofolliculomas can be removed surgically, through curettage, shave excision, skin resurfacing, or laser ablation; this is not a permanent solution, though, as the tumors often recur. The renal and pulmonary symptoms are managed preventatively: CT scans, ultrasounds, or MRIs of the kidneys are recommended regularly, and family members are advised not to smoke. MRIs are the preferred method for surveillance of the kidneys in people with BHD because they do not carry the same risk of radiation complications as CT scans, and are more sensitive than ultrasounds. Smokers with<unk> –Hogg–Dubé have more severe pulmonary symptoms than non-smokers. Though nephrectomy is sometimes indicated, kidney tumors in cases of BHD are often removed without taking the whole kidney, in a partial nephrectomy. Knockout mouse studies have shown that administration of rapamycin may mitigate the effects of FLCN mutations on kidneys and improve renal cancer prognoses because of folliculin's interaction with the mTOR pathway.
Birt–Hogg–Dubé syndrome
Johnson–McMillin syndrome
Fox–Fordyce disease
Cruveilhier–Baumgarten disease
Yemenite deaf-blind hypopigmentation syndrome
Beare–Stevenson cutis gyrata syndrome
Sézary disease
Ardalan–Shoja–Kiuru syndrome