<unk>  belongs to the Sp/KLF family of<unk>  factors. The protein is 785 amino acids long, with a molecular weight of 81 kDa. The<unk>  contains two glutamine-rich activation domains at its N-terminus that are believed to be necessary for promoter trans-activation.<unk>  most notably contains three zinc finger protein motifs at its C-terminus, by which it binds directly to DNA and allows for interaction of the protein with other<unk> al regulators. Its zinc fingers are of the Cys2/His2 type and bind the consensus sequence 5'-(G/T)GGGCGG(G/A)(G/A)(C/T)-3' (GC box element). Some 12,000 SP-1 binding sites are found in the human genome.
Sp1 transcription factor
STAT protein
Winged-helix transcription factors
Origin recognition complex
Mir-590 microRNA precursor family
Core binding factor
Mir-618 microRNA precursor family
Mir-3180 microRNA precursor family