<unk> , sold under the brand names ReVia and Vivitrol among others, is a medication primarily used to manage alcohol or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found to be effective in the treatment of other addictions and may be used for them off-label. An opioid-dependent person should not receive<unk>  before detoxification. It is taken by mouth or by injection into a muscle. Effects begin within 30 minutes. A decreased desire for opioids may take a few weeks to occur. Side effects may include trouble sleeping, anxiety, nausea, and headaches. In those still on opioids, opioid withdrawal may occur. Use is not recommended in people with liver failure. It is unclear if use is safe during pregnancy.<unk>  is an opioid antagonist and works by blocking the effects of opioids, both those from inside and outside the body.<unk>  was first made in 1965 and was approved for medical use in the United States in 1984.<unk> , as<unk> /bupropion (brand name Contrave), is also used to treat obesity.
Naltrexone
Normethadone
Isomethadone
Methadone
Buprenorphine
Guanfacine
Nabilone
Atomoxetine