<unk>  (KRS) is an autosomal recessive disorder of juvenile onset also known as Parkinson disease-9 (PARK9). It is named after<unk><unk>  in Irbid, Jordan.<unk>  was first identified in this region in Jordan with a Jordanian couple's 5 children who had rigidity, mask-like face, and bradykinesia. The disease was first described in 1994 by Najim Al-Din et al. The OMIM number is 606693. Less than 50 individuals have been reported to have KRS. Typically, rapid onset of symptoms occurs between the ages of 12 and 16. It is important to conduct genetic testing to screen family members, so the disease can be detected early and symptoms can be managed. ATP13A2 gene mutations are associated with<unk> . The ATP13A2 mutation was first identified in 2010. This syndrome is identified to have a compound heterozygous or homozygous mutation in the ATP13A2 gene. This mutation is located on chromosome 1 and codes for a lysosomal type 5 ATPase. Patients have been identified to have iron in their basal ganglia.
Kufor–Rakeb syndrome
Kufs disease
Zunich–Kaye syndrome
Irlen syndrome
Simpson–Golabi–Behmel syndrome
Naxos syndrome
Cornelia de Lange syndrome
Letterer–Siwe disease