The disease has been reported to affect 3 per 1000 infants younger than 6 months in the United States. No predilection by race or sex has been established. Almost all cases occur by the age of 5 months. The familial form is inherited in an autosomal dominant fashion with variable penetrance. The familial form tends to have an earlier onset and is present at birth in 24% of cases, with an average age at onset of 6.8 weeks. The average age at onset for the sporadic form is 9–11 weeks.<unk><unk>  is a potential side effect of long-term use of prostaglandins in neonates.
Infantile cortical hyperostosis
Acrofrontofacionasal dysostosis
Melorheostosis
Acrodysostosis
Pycnodysostosis
Buccal exostosis
Spondylocostal dysostosis
Thanatophoric dysplasia