<unk>  (DTOT) is a method of treating warts by covering them with<unk> <unk>  for prolonged periods. The manner in which<unk> <unk>  appears to work is unclear. The<unk>  might create a macerating and keratolytic environment, stimulating an immune response. The type of adhesive in the<unk> <unk>  is likely to be important as leeching of the adhesive into the skin may be causing the immune system response. Side effects can include skin irritation and peeling. There is mixed evidence that occlusive treatment with various types of<unk> <unk>  is effective. Clinical trials in 2012 concluded that no statistically significant difference between clear<unk> <unk>  and placebo could be determined within the sample. On health information websites,<unk> <unk>  is referred to as a treatment with mixed evidence of efficacy, no good evidence or described as alternative medicine. __TOC__
Duct tape occlusion therapy
Bridge therapy
Hassab's decongestion operation
Clitoral enlargement methods
Piezoelectric surgery
Natural orifice transluminal endoscopic surgery
Michelassi strictureplasty
Helmet removal 