Chemistry and mechanism of action Contrast CT of a patient with brain metastases from breast cancer, before (left) and after (right) injection of an iodine-containing contrast agent<unk>  is an iodine-containing, water-soluble radiocontrast agent. The iodine atoms readily absorb X-rays, resulting in a higher contrast of X-ray images. It has a low osmolality of 600 mosm/kg water at , meaning that the solution has a relatively low concentration of molecules; this is usually associated with fewer adverse effects than high-osmolality contrast agents. Pharmacokinetics After injection into a vein, 14% of the circulating<unk>  is bound to blood plasma proteins, which is unusually high for a water-soluble iodinated contrast agent. The substance is distributed in the body with a half-life of 12 minutes (range 4 to 17 minutes) and eliminated in unmetabolized (unchanged) form via the kidneys with a half-life of 92 minutes (range 61 to 140 minutes). In people with kidney failure, it is eliminated via the bile duct, saliva or sweat.
Ioxaglic acid
Ellagic acid
Tienilic acid
Bempedoic acid
Alpha-Zearalenol
Ricin
Vilanterol
Echinopsidine