* Gender— approximately twice as common in women than men, usually in seventh and eighth decades * Obesity * Chronic cholecystitis and cholelithiasis * Primary sclerosing cholangitis * Chronic typhoid infection of gallbladder; chronic Salmonella typhi carriers have 3 to 200 times higher risk of<unk>  than non-carriers and 1–6% lifetime risk of development of cancer * Various single nucleotide polymorphisms (SNPs) have been shown to be associated with<unk> ; however, existing genetic studies in<unk>  susceptibility have so far been insufficient to confirm any association * Gallbladder polyps * Calcified gallbladder wall (porcelain gallbladder) * Congenital abnormalities of the bile duct such as choledochal cyst
Gallbladder cancer
Human digestive system
Liver cancer
Hepatolithiasis
Pancreatic cancer
Gallbladder disease
Liver abscess
Duodenal cancer