Cancer and Diabetes It has been reported that people with<unk>  in Ecuador are resistant to cancer and diabetes and are somewhat protected against aging. This is consistent with findings in mice with a defective growth hormone receptor gene. Among the approximately 100 individuals in this population, there were no reported cases of diabetes and one case of cancer. A 2019 study of individuals with isolated growth hormone deficiency (IGHD type 1B) in Itabaianinha County, Brazil demonstrated a phenotype consistent with<unk> . Researchers found that these humans had similarly extended healthspan, with resistance to cancer and attenuated effects of aging, but neither patients with<unk>  nor IGHD experienced an increase in their overall lifespan.
Laron syndrome
Hypopituitarism
Jervell and Lange-Nielsen syndrome
STAT5B
Aagenaes syndrome
Cowden syndrome
Dennie–Marfan syndrome
Prader–Willi syndrome