Density-Dependent Colour Scanning Electron Micrograph SEM (DDC-SEM) of<unk>  calcification, showing in orange calcium phosphate spherical particles (denser material) and, in green, the extracellular matrix (less dense material) Population-based studies show that atherosclerosis, the major precursor of<unk> , begins in childhood. The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study demonstrated that intimal lesions appear in all the aortas and more than half of the right coronary arteries of youths aged 7–9 years. Obesity and diabetes mellitus are linked to<unk> , as are a history of chronic kidney disease and hypercholesterolaemia. In fact,<unk>  is the most life-threatening of the diabetic complications and diabetics are two- to four-fold more likely to die of<unk> -related causes than nondiabetics.
Cardiovascular disease
Panic disorder
Cancer
Anxiety disorder
Disease
Panic attack
Gastrointestinal disease
Cerebrovascular disease