Worms<unk>  was originally used as an anthelmintic to treat worm infestations in both humans and animals.<unk>  works as a nicotinic acetylcholine receptor agonist that causes continued stimulation of the parasitic worm muscles, leading to paralysis. In countries that still permit the use of<unk> , the recommended dose for anthelmintic therapy is a single dose, with a repeated dose 7 days later if needed for a severe hookworm infection. Most current commercial preparations are intended for veterinary use as a dewormer in cattle, pigs, and sheep. However,<unk>  has also recently gained prominence among aquarists as an effective treatment for Camallanus roundworm infestations in freshwater tropical fish. Cancer After being pulled from the market in the U.S. and Canada in 1999 and 2003, respectively,<unk>  has been tested in combination with fluorouracil to treat colon cancer. Evidence from clinical trials support its addition to fluorouracil therapy to benefit patients with colon cancer. In some of the leukemic cell line studies, both<unk>  and tetramisole showed similar effect. Other<unk>  has been used to treat a variety of dermatologic conditions, including skin infections, leprosy, warts, lichen planus, and aphthous ulcers. An interesting side effect these reviewers reported in passing was "neurologic excitement". Later papers, from the Janssen group and others, indicate<unk>  and its enantiomer, dexamisole, have some mood-elevating or antidepressant properties, although this was never a marketed use of the drug.
Levamisole
Dimetacrine
Avermectin
Pyrantel
Ivermectin
Silver sulfadiazine
Piretanide
Salicylic acid