Pharmacodynamics<unk>  is a corticosteroid, acting specifically as both a glucocorticoid and as a mineralocorticoid. That is, it is an agonist of the glucocorticoid and mineralocorticoid receptors.<unk>  has low potency relative to synthetic corticosteroids. Compared to<unk> , prednisolone is about 4 times as potent and dexamethasone about 40 times as potent in terms of anti-inflammatory effect. Prednisolone can also be used as cortisol replacement, and at replacement dose levels (rather than anti-inflammatory levels), prednisolone is about eight times more potent than cortisol. Pharmacokinetics Most cortisol in the blood (all but about 4%) is bound to proteins, including corticosteroid binding globulin (CBG) and serum albumin. Free cortisol passes easily through cellular membranes, explaining its 100% bioavailability after oral administration. Inside cells it interacts with corticosteroid receptors.
Hydrocortisone
Methandriol
Cortisone
Cortisone acetate
Calcipotriol
Dexamethasone
Testosterone propionate
Fludrocortisone