In desensitization<unk>  the aim is to induce or restore tolerance to the<unk>  by reducing its tendency to induce IgE production. People are desensitized through the administration of escalating doses of<unk>  that gradually decreases the IgE-dominated response. The objective of<unk>  is to direct the immune response away from humoral immunity and toward cellular immunity, thereby encouraging the body to produce fewer IgE antibodies and more CD4+ T regulatory cells that secrete IL-10 and TGF-β, which skews the response away from IgE production. Oral<unk>  also creates an increase in<unk> -specific IgG4 antibodies and a decrease in<unk> -specific IgE antibodies, as well as diminished mast cells and basophils, two cell types that are large contributors to allergic reaction.
Allergen immunotherapy
Ozone therapy
Maggot therapy
Asthma spacer
Helminthic therapy
T-cell vaccination
Antigen-presenting cell vaccine
Aerosol-generating procedure