Frontotemporal lobar degeneration (FTLD) is a pathological process that occurs in frontotemporal dementia. It is characterized by atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes. Common proteinopathies that are found in FTLD include the accumulation of tau proteins and TAR DNA-binding protein 43 (TDP-43). Mutations in the C9orf72 gene have been established as a major genetic contribution of FTLD, although defects in the granulin (GRN) and microtubule-associated proteins (MAPs) are also associated with it.
causes of Frontotemporal dementia
medical cause of Frontotemporal dementia
complications of Frontotemporal lobar degeneration
causes of Gerstmann syndrome
medical cause of Metachromatic leukodystrophy
symptom of Pantothenate kinase-associated neurodegeneration
symptom of Transmissible spongiform encephalopathy
risks of Alzheimer's disease