<unk>  (brand names Imiprex, Elepsin), or imipramine N-oxide, is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1960s for the treatment of depression.<unk>  is both an analogue and a metabolite of imipramine, and has similar effects. However, in clinical trials,<unk>  was found to have a faster onset of action, slightly higher efficacy, and fewer and less marked side effects, including diminished orthostatic hypotension and anticholinergic effects like dry mouth, sweating, dizziness, and fatigue.<unk> 's pharmacology has not been well elucidated, but based on its very close relationship with imipramine, it likely acts as a serotonin and norepinephrine reuptake inhibitor and serotonin, adrenenaline, histamine, and muscarinic acetylcholine receptor antagonist, though with weaker antiadrenergic and anticholinergic actions.<unk>  has been said to be a prodrug of imipramine.
Imipraminoxide
Toremifene
Tasimelteon
Pulmocide
Co-dydramol
Plerixafor
Deflazacort
Mitapivat