<unk>  is mainly used as a diuretic.<unk>  has been found to be effective in the treatment of hirsutism in women. Heart failure Two studies of<unk>  in people with heart failure have shown a mortality benefit compared to placebo. In the evaluation which studied people with chronic heart failure (CHF), people that were treated with<unk>  displayed a lower number of deaths compared to the placebo group, indicating a death and morbidity benefit of the medication. One study compared 166 treated with<unk>  to 336 given conventional therapy lasting 10 years. Differences in systolic and diastolic blood pressure was observed between both patient groups where, patients treated with<unk> , showed a lower blood pressure compared to conventional therapy. Uric acid was lower in the group treated with<unk> ; however, no differences were seen in potassium, sodium, and brain natriuretic peptide (BNP) levels. Left ventricular mass was also lower in the group treated with<unk>  and a greater progression of NYHA class was observed in the control group compared to patients treated with<unk> . Another study concluded that treatment with<unk>  in patients with chronic heart failure improves diastolic function and further decreased BNP levels.
Canrenone
Eplerenone
Spirorenone
Finerenone
7α-Thiospironolactone
Cyclothiazide
Spironolactone
Olmesartan