Early detection of<unk>  is usually via MRI. The iron deposition that is characteristic of<unk>  shows up as a hypointense band in affected tissues, with a characteristic rim of intensity appearing on the cerebellum; a hyperintense rim is rarely seen. Taking samples of cerebrospinal fluid may also reveal<unk>  through xanthochromia, elevated presence of red blood cells, high iron and ferritin concentrations, and elevated levels of the proteins Tau, amyloid beta (Aβ42), neurofilament light chain (NFL), and glial fibrillary acidic protein (GFAP), but the CSF is sometimes normal. Detection is complicated by the fact that<unk>  is a rare disease and is not well described in neurological texts, so it may go unnoticed until noticeable symptoms appear.
Superficial siderosis
Geographic atrophy
Neurofibrillary tangle
Polymicrogyria
Posterior cortical atrophy
Amyloid plaques
Hippocampal sclerosis
Hemosiderin hyperpigmentation