<unk>  is defined in the DSM IV as depression that shares many of the<unk>  symptoms of major depressive disorder or dysthymia but is characterized by improved mood in response to positive events. In contrast to those with<unk> , people with melancholic depression generally do not experience an improved mood in response to normally pleasurable events.<unk>  also often features significant weight gain or an increased appetite, hypersomnia, a heavy sensation in the limbs, and interpersonal rejection sensitivity that results in significant social or occupational impairment. Despite its name,<unk> " depression does not mean it is uncommon or unusual. The reason for its name is twofold: it was identified with its "unique" symptoms subsequent to the identification of melancholic depression and its responses to the two different classes of antidepressants that were available at the time were different from melancholic depression (i.e., MAOIs had clinically significant benefits for<unk> , while tricyclics did not).<unk>  is four times more common in females than in males. Individuals with features of<unk>  tend to report an earlier age of onset (e.g. while in high school) of their depressive episodes. These episodes tend to be more chronic than those of major depressive disorder and only have partial remission between episodes. Younger individuals may be more likely to have<unk>  features, whereas older individuals may more often have episodes with melancholic features.<unk>  has high comorbidity with anxiety disorders, carries more risk of suicidal behavior, and has distinct personality psychopathology and biological traits.<unk>  is more common in individuals with bipolar I, bipolar II, cyclothymia or seasonal affective disorder. Depressive episodes in bipolar disorder tend to have<unk>  features, as does depression with seasonal patterns.
Atypical depression
Melancholic depression
Outline of bipolar disorder
Anxiety disorder
Transference neurosis
Late life depression
Retarded depression
Treatment-resistant depression