<unk>  blood<unk>  cell transplantation (PBSCT), also called<unk> <unk>  cell support", is a method of replacing blood-forming<unk>  cells.<unk>  cells can be destroyed through cancer treatments such as chemotherapy or radiation, as well as any blood-related diseases, such as leukemia, lymphoma, neuroblastoma and multiple myeloma. PBSCT is now a much more common procedure than its bone marrow harvest equivalent due to the ease and less invasive nature of the procedure. Studies suggest that PBSCT has a better outcome in terms of the number of hematopoietic<unk>  cell (CD34+ cells) yield. Immature hematopoietic<unk>  cells in the circulating blood that are similar to those in the bone marrow are collected by apheresis from a donor (PBSC collection). The product is then administered intravenously to the patient after treatment. The administered hematopoietic<unk>  cells then migrate to the recipient's bone marrow, through a process known as<unk>  cell homing, where the transplanted cells override the previous bone marrow. This allows the bone marrow to recover, proliferate and continue producing healthy blood cells. The transplantation may be autologous (an individual's own blood cells), allogeneic (blood cells donated by someone else with matching HLA), or syngeneic (blood cells donated by an identical twin). The apheresis procedure typically lasts for 4–6 hours, depending on the blood volume of the donor.
Peripheral stem cell transplantation
Thymus transplantation
Syngeneic stem cell transplantation
Stem-cell therapy
Hematopoietic stem cell transplantation
Autologous stem-cell transplantation
Spleen transplantation
Autologous immune enhancement therapy