<unk> s arise when precursor cells (blast cells) of the myeloid lineages in the bone marrow develop somatic mutations which cause them to grow abnormally. There is a similar category of disease for the lymphoid lineage, the lymphoproliferative disorders acute lymphoblastic leukemia, lymphomas, chronic lymphocytic leukemia and multiple myeloma. Genetics is believed to play a central role in the development of<unk> s, specially in developing thromboembolic and bleeding complications.
Myeloproliferative neoplasm
Lymphoproliferative disorders
Immunoproliferative disorder
Autoimmune neutropenia
Leukemoid reaction
Myelodysplastic syndrome
B-cell leukemia
B-cell lymphoma