Lesions under MRI are distinctive due to their natural<unk>  shape. Under a lumbar puncture CSF test, with Baló's<unk><unk> , as well as patients with pattern III lesions, were recently shown to be mostly negative for CSF-restricted oligoclonal bands. Also pattern III patients tend to be negative under the MRZ-reaction (measles, rubeola and zoster viruses) Paediatric cases Baló's<unk><unk>  in children has been reported to behave different from adults Lesions in autopsy and biopsy A report comparing 1H-magnetic resonance spectroscopy, magnetization transfer and diffusion tensor imaging with histopathology in a patient with Baló's<unk><unk> , found that inflammation was traced by fractional anisotropy and increased lactate. In contrast, magnetization transfer ratio and the diffusion coefficient show a loss of tissue in the rings of the lesion. Lesions under MRI The features of the MRI and the characteristics of the lesion can be correlated when a biopsy has been taken, providing a way to standardize the future MRI diagnosis Baló's<unk><unk>  lesions can be distinguished from normal lesions on MRI showing alternating hypointense and hyperintense layers Baló's<unk>  lesions can be viewed using the myelin water imaging techniques. This is a special MRI sequence that shows the myelin's percentage of water content. Pattern III lesions, including Baló lesions, have a specific initiation pattern under MRI (MRILIP) consisting in showing Gadolinium enhancement before FLAIR MRI appearance. Under 7-Tesla MRI Ball lesions show a center vein, like in MS.
Balo concentric sclerosis
Tunnel cluster
Myopic crescent
Contour threads
Neurofibrillary tangle
Storiform pattern
Polymicrogyria
Vossius ring