Diagnosing<unk>  requires extensive patient history alongside a physical and neurological examination. KRS can be suspected in individuals with juvenile-onset Parkinsonism in their first 10–20 years of age. In patients with KRS, MRI imaging can show cerebral atrophy and an accumulation of iron in the basal ganglia. This accumulation of iron is referred to as NBIA, or neurodegeneration with brain iron accumulation, and it is a symptom unique to a complex group of inherited neurodegenerative diseases such as KRS, characterized by this accumulation of iron in the basal ganglia. Additionally, genetic screening through sequence analysis can allow definitive diagnoses of the disease by identifying mutations in the ATP13A2 gene, a gene closely associated with<unk> .
Kufor–Rakeb syndrome
Kufs disease
Zunich–Kaye syndrome
Irlen syndrome
Simpson–Golabi–Behmel syndrome
Naxos syndrome
Cornelia de Lange syndrome
Letterer–Siwe disease