While<unk>  hypertrophy occurs naturally as a reaction to aerobic exercise and strength training, it is most frequently referred to as a pathological reaction to cardiovascular disease, or high blood pressure. It is one aspect of<unk>  remodeling. While<unk>  itself is not a disease, it is usually a marker for disease involving the heart. Disease processes that can cause<unk>  include any disease that increases the afterload that the heart has to contract against, and some primary diseases of the muscle of the heart. Causes of increased afterload that can cause<unk>  include aortic stenosis, aortic insufficiency and hypertension. Primary disease of the muscle of the heart that cause<unk>  are known as hypertrophic cardiomyopathies, which can lead into heart failure. Long-standing mitral insufficiency also leads to<unk>  as a compensatory mechanism. Associated genes include OGN, osteoglycin.
Left ventricular hypertrophy
Athletic heart syndrome
Right ventricular hypertrophy
Aortic unfolding
Ventricular hypertrophy
Atrial enlargement
Left atrial enlargement
Right atrial enlargement