<unk>  <unk> , also known as black typhus or Ordog<unk> , is a hemorrhagic<unk>  and zoonotic infectious disease originating in<unk> after infection by Machupo mammarenavirus.<unk>  was first identified in 1963 as an ambisense RNA virus of the Arenaviridae family, by a research group led by Karl Johnson. The mortality rate is estimated at 5 to 30 percent. Due to its pathogenicity, Machupo virus requires Biosafety Level Four conditions, the highest level. During the period between February and March 2007, some 20 suspected<unk>  cases (3 fatal) were reported to the Servicio Departamental de Salud (SEDES) in Beni Department,<unk>  In February 2008, at least 200 suspected new cases (12 fatal) were reported to SEDES. In November 2011, a second case was confirmed near the departmental capital of Trinidad, and a serosurvey was conducted to determine the extent of Machupo virus infections in the Department. A SEDES expert involved in the survey expressed his concerns about the expansion of the virus to other provinces outside the endemic regions of Mamoré and Iténez provinces.
Bolivian hemorrhagic fever
Omsk hemorrhagic fever
Argentine hemorrhagic fever
Crimean–Congo hemorrhagic fever
Venezuelan hemorrhagic fever
Viral hemorrhagic fever
Dengue fever
West Nile fever