<unk>  is an oral NS3 serine protease inhibitor of hepatitis C virus. It inhibits viral replication in infected host cells. The mechanism of inhibition involves reversible covalent binding of<unk>  with NS3 protease active site via the ketoamide functional group.<unk>  does not bind to human proteases, with the exception of cathepsin B (69% inhibition). Overexpression of cathepsin B is associated with the development of malignancies.
Narlaprevir
Simeprevir
Glecaprevir
Telaprevir
Saquinavir
Grazoprevir
Fostemsavir
Abacavir