<unk>  has been used in many Asian and European countries for treatment of cerebrovascular disorders such as stroke and dementia for over three decades.<unk>  is not approved for any therapeutic use in the United States. The FDA has tentatively ruled that<unk> , due to its synthetic nature and proposed therapeutic uses, is ineligible to be marketed as dietary supplement under the Federal Food, Drug, and Cosmetic Act. Despite this,<unk>  remains widely available in dietary supplements often marketed as nootropics.<unk>  is legally sold in Canada. Refer to the Health Canada website, for more details.<unk>  does not fully support a benefit in either dementia or stroke. As of 2003, three controlled clinical trials had tested "older adults with memory problems".<unk>  is licensed by Health Canada to be sold, as a supplement, for the following recommended uses: "to help improve cognitive function in those with age related cognitive decline," and "to improve memory and cognition," (in addition to other purposes/uses when taken in adjunction to other chemicals and/or herbs).
Vinpocetine
Reboxetine
Carpipramine
Pirlindole
Paroxetine
Nabilone
Trimipramine
Lorpiprazole