HLA(haplotypes) In terms of genetics one finds that autoimmune polyendocrine syndrome<unk> 2 has an autosomal dominant pattern of inheritance, with an incomplete penetrance. Furthermore, the human leukocyte antigen involved in this condition are HLA-DQ2(DR3 (DQB*0201)) and HLA-DQ8(DR4 (DQB1*0302)), genetically speaking, which indicates this is a multifactorial disorder, as well. Should any affected organs show chronic inflammatory infiltrate (lymphocytes), this would be an indication. Moreover, autoantibodies reacting to specific antigens is common, in the immune system of an affected individual.
types of Autoimmune polyendocrine syndrome
symptoms of Autoimmune polyendocrine syndrome type 1
symptom of Autoimmune polyendocrine syndrome type 1
medical cause of Zollinger–Ellison syndrome
complications of Hashimoto's thyroiditis
symptom of Maroteaux–Lamy syndrome
complications of Graves' disease
medical cause of Hyperthyroidism