ITCLD-GT occurs more commonly in males of middle age (median age 48.4, range 15–77 years in one study). Individuals with the disease present with GI tract symptoms which often are serious and/or debilitating and may mimic those occurring in malignant<unk> , inflammatory, or autoimmune bowel diseases. These symptoms include chronic epigastric pain, abdominal pain, heartburn, nausea, diarrhea, vomiting, weight loss, relapsing oral ulcers, relapsing colorectal ulcers, rectal bleeding, and/or night sweats. Several patients presenting with these symptoms have been diagnosed with and unsuccessfully treated for peripheral T-cell lymphoma, an inflammatory bowel disease (either Crohn disease or ulcerative colitis), or the autoimmune GI tract<unk> , celiac disease. It has been shown or appears very likely that these patients had ITCLD-GT rather than the cited diagnoses.
Indolent T cell lymphoproliferative disorder of the gastrointestinal tract
Foreign body in alimentary tract
Effects of parasitic worms on the immune system
Small intestine neuroendocrine tumor
Autoimmune gastrointestinal dysmotility
Multifocal stenosing ulceration of the small intestine
Gastric antral vascular ectasia
Cystic lesions of the pancreas