<unk>  may result in failure of treatment due to the increased elimination of drugs. This can be prevented by increasing the dosage of the medication, or by increasing the frequency the medication is administered to account for increased elimination. ARC influences the recommended dosages for antibiotics including aminoglycosides, beta-lactams, fluoroquinolones, and vancomycin in critical care. In any case, the occurrence of ARC is managed through pharmacokinetic monitoring and adjusting medication dosages, frequencies, or timing to ensure adequate response. The occurrence of ARC can also impact medications that are unrelated to an acute illness, such as levetiracetam for seizures. People taking a stable dose of levetiracetam at home may require an increased dose when critically ill in a hospital to maintain efficacy.
Augmented renal clearance
Enhanced permeability and retention effect
Bioconcentration
Electrolyte exclusion effect
Natriuresis
Renal compensation
Prostatic congestion
Adrenal fatigue