Diagram of autosomal dominant inheritance pattern The three types of<unk>  are caused by different mutations on chromosomes.<unk> 1 is caused by a mutation on the<unk> 1 gene on the arm of chromosome 17.<unk> 2 is caused by a mutation on the<unk> 2 tumor suppressor gene on chromosome 22. Schwannomatosis is caused by various mutations on chromosome 22.<unk>  is an autosomal dominant disorder, which means only one copy of the affected gene is needed for the disorder to develop. If one parent has<unk> , his or her children have a 50% chance of developing the condition as well. The severity of the parent's condition does not affect the child; the affected child may have mild<unk> 1 even though it was inherited from a parent with a severe form of the disorder. The types of<unk>  are: *<unk>  type I, in which the nerve tissue grows tumors (neurofibromas) that may be benign, but may cause serious damage by compressing nerves and other tissues. *<unk>  type II, in which bilateral acoustic neuromas (tumors of the vestibulocochlear nerve or cranial nerve 8 (CN VIII) also known as schwannoma) develop, often leading to hearing loss. * Schwannomatosis, in which painful schwannomas develop on spinal and peripheral nerves.
Neurofibromatosis
Tuberous sclerosis
Fox–Fordyce disease
Ollier disease
Irlen syndrome
Progeria
Fabry disease
Degos disease