225px AIDS ("acquired immune deficiency syndrome") is caused by the human immunodeficiency virus <unk> . Individuals with<unk>  have what is referred to as a "HIV infection". When infected semen, vaginal secretions, or blood come in contact with the mucous membranes or broken skin of an uninfected person,<unk>  may be transferred to the uninfected person ("horizontal transfer"), causing another infection. Additionally,<unk>  can also be passed from infected pregnant women to their uninfected baby during pregnancy and/or delivery ("vertical transmission"), or via breastfeeding. As a result of<unk>  infection, a portion of these individuals will progress and go on to develop clinically significant AIDS.<unk>  is a retrovirus, which comprise a large and diverse family of RNA viruses that make a DNA copy of their RNA genome after infection of a host cell. An essential step in the replication cycle of<unk> -1 and other retroviruses is the<unk>  of this viral DNA into the host DNA. The RNA genome of progeny virions and the template for translation of viral proteins are made when the integrated viral DNA is transcribed.
HIV integration
Fusion gene
Oncogene
Virus latency
Low copy repeats
Tissue tropism
Anticancer gene
Active chromatin sequence