<unk><unk>  of the CNS is pan-ethnic, due to its prevalence among Ashkenazi Jews. There are two common mutations found among them: missense mutation (Glu285AIa) and nonsense mutation (Tyr231X). In the missense mutation, there is a substitution of glutamic acid to alanine. As for the nonsense mutation, the tyrosine codon is replaced by a termination codon. Genetic screening reveals that around 1 in 40 healthy Jews are carriers and the incidence of this disease in this population is as high as 1 in 6000.
Spongy degeneration of the central nervous system
Lesional demyelinations of the central nervous system
Inflammatory demyelinating diseases of the central nervous system
Visual pathway lesions
Neurogenic inflammation
Central nervous system fatigue
Effects of early-life exposures to anesthesia on the brain
Neurodegeneration with brain iron accumulation