* Fever occurs in 97% of people; malaise and endurance fatigue in 90% of people. * A new or changing heart murmur, weight loss, and coughing occurs in 35% of people. * Vascular phenomena: septic embolism (a piece of infected debris or tissue breaking off and traveling through the bloodstream to a distant site) (causing thromboembolic problems such as a stroke or gangrene of the fingers), Janeway lesions (painless hemorrhagic cutaneous lesions on the palms and soles), bleeding in the brain, conjunctival hemorrhage, splinter hemorrhages, kidney infarcts, and splenic infarcts.<unk>  can also lead to the formation of mycotic aneurysms. * Immunologic phenomena: glomerulonephritis which allows for blood and albumin to enter the urine, Osler's nodes ("ephemeral spots of a painful nodular erythema, chiefly in the skin of the hands and feet"), Roth's spots on the retina, positive serum rheumatoid factor * Other signs may include night sweats, rigors, anemia, spleen enlargement
Infective endocarditis
Libman–Sacks endocarditis
Loeffler endocarditis
Nonbacterial thrombotic endocarditis
Subacute bacterial endocarditis
Tuberculous pericarditis
Nocardiosis
Ischemic cardiomyopathy