The first red flag that indicates M2<unk>  is the skewed ratio of white blood cells to red blood cells. Leukemia is initially diagnosed by a peripheral blood smear, a procedure used to check for cell count and cell shapes. Then a bone marrow aspiration and biopsy would be conducted to collect and view the bone, bone marrow, and blood under a microscope. Cytogenetic assays, such as fluorescence in situ hybridization (FISH) would help evaluate the structure and function of the cell's chromosomes. The criteria for an acute myeloid leukemia case to fall under the M2 subtype is the following: 20%+ nonerythroid cells in peripheral blood or bone marrow are myeloblasts; monocytic precursors are < 20% in bone marrow and granulocytes are 10%+ of cells (Mihova, 2013).
Acute myeloblastic leukemia with maturation
Acute myeloblastic leukemia without maturation
B-cell prolymphocytic leukemia
Minimally differentiated acute myeloblastic leukemia
Acute megakaryoblastic leukemia
Precursor B-cell lymphoblastic leukemia
Prolymphocytic leukemia
T-cell prolymphocytic leukemia