IEIs were historically considered very rare, affecting only 1 in 10,000 – 50,000 births. As more IEIs are described and clinical phenotypes are defined more precisely, their true prevalence may be more common. More recent estimates place prevalence at 1 in 1,000 – 10,000 births.
Inborn errors of immunity
Combined immunodeficiencies
Primary immunodeficiency
MOG antibody disease
Transient hypogammaglobulinemia of infancy
Selective immunoglobulin A deficiency
Neonatal adrenoleukodystrophy
Inborn errors of metabolism