Using the<unk>  hydrogen peroxide as an example, no adverse effects are expected with overdose of an otic administered preparation. The average middle ear volume is 0.4 mL, which limits otic accumulation in overdose. It is unlikely that an<unk>  administered into the ear would cause systemic toxicity in an overdose situation, due to the lack of systemic absorption resulting from minimal volume flow within the inner ear. However, again using hydrogen peroxide as an example, clinically relevant overdoses of<unk> s are possible if the drugs are administered by other routes (e.g. by mouth).
Cerumenolytic
Keratolytic
Hematinic
Titratable acid
Cryosupernatant
Protelean
Toxicophore
Antimetabolite