Children with<unk>  tend to look similar and have distinctive physical and craniofacial characteristics, which may include several, but not all of the following features: * Macrocephaly * Large bifrontal diameter * Flattened occiput * Long philtrum * Retrognathia * Round face in infancy * Prominent chin crease * Large ears * Strabismus * Hypertelorism * Epicanthal folds * Downslanting palpebral fissures Other features may include loose skin, thin deep-set nails, thin hair, short ribs, limited elbow and knee extension, camptodactyly, and a coarse, low-pitched voice. Delayed development of motor skills such as sitting, standing, and walking are commonly exhibited in early childhood. Patients with<unk>  typically have mild intellectual disability with poor coordination and balance. They also have some neurological abnormalities such as speech delay, epilepsy, intellectual disability, hypotonia or hypertonia, and behavioral problems.
Weaver syndrome
Seaver Cassidy syndrome
Temple–Baraitser syndrome
Nance–Horan syndrome
Parinaud's syndrome
Adams–Nance syndrome
Frey's syndrome
Cohen syndrome