<unk>  (HSD), related to earlier diagnoses such as<unk>  syndrome (HMS), and joint<unk>  syndrome (JHS) is a heritable connective tissue<unk>  that affects joints and ligaments. Different forms and sub-types have been distinguished, but it does not include asymptomatic joint<unk> , sometimes known as double-jointedness. Symptoms can include the inability to walk properly or for long distances, and pain in affected areas. Some people with HSD have hypersensitive nerves and a weaker immune system. It can also cause severe fatigue and some cases cause depressive episodes. It is somewhat similar to other genetic connective tissue<unk> s such as Ehlers–Danlos syndromes. There is a strong association between HSD and neurodevelopmental<unk> s such as ADHD (Attention deficit hyperactivity<unk>  and ASD (autism<unk><unk> .
Hypermobility spectrum disorder
Arthrogryposis
Limb girdle syndrome
Hereditary neuropathy with liability to pressure palsy
Lethal arthrogryposis with anterior horn cell disease
Barth syndrome
Adrenoleukodystrophy
Hereditary spastic paraplegia