Ayahuasca being prepared in the Napo region of Ecuador A spoonful of promethazine/codeine cough syrup showing the characteristic purple color that gave rise to the name purple drank.|alt=Close-up photo of a metal spoon filled with a viscous, clear purple fluid<unk>  or poly drug use or refers to the use of combined psychoactive substances.<unk>  may be used for entheogenic, recreational, or off-label indications, with both legal and illegal substances. In many cases one drug is used as a base or primary drug, with additional drugs to leaven or compensate for the side effects, or tolerance, of the primary drug and make the experience more enjoyable with drug synergy effects, or to supplement for primary drug when supply is low.
Polysubstance use
Alcohol abuse
Alcohol dependence
Substance abuse
Substance Abuse
Alcohol intoxication
Recreational drug use
Video game addiction