Though it is more likely to cause infection,<unk>  trauma is similar to closed<unk>  injury such as cerebral contusion or intracranial hemorrhage. As in closed<unk>  injury, intracranial pressure is likely to increase due to swelling or bleeding, potentially crushing delicate brain tissue. Most deaths from<unk>  trauma are caused by damage to blood vessels, which can lead to intracranial hematomas and ischemia, which can in turn lead to a biochemical cascade called the ischemic cascade. The injury in<unk>  brain trauma is mostly focal (that is, it affects a specific area of tissue). Studies with PET scanning and transcranial Doppler imaging have shown that changes in cerebral blood flow, such as hypoperfusion and vasospasm, can follow<unk> . These changes can last for two weeks. An ischemic cascade similar to the course of cellular and metabolic events that follow other<unk>  injuries may follow<unk> es. Sometimes in<unk>  injuries, the brain releases thromboplastin, which can lead to problems with blood clotting. While blunt trauma to the<unk>  does not present a risk of shock due to hemorrhage,<unk> <unk>  trauma does.
Penetrating head injury
Closed-head injury
Traumatic brain injury
Acquired brain injury
Cerebral contusion
Traumatic asphyxia
Polytrauma
Pediatric concussion