<unk>  affects the body's mitochondria and can have a variety of presentations. In some cases, the brain, heart, liver, kidneys, and muscles are affected, while in other cases, only the heart and muscles are affected with adult onset. Common symptoms include the Babinski sign, muscle weakness, distal amyotrophy (muscle wasting of the limbs), developmental regression (loss of developmental milestones), and being easy to fatigue.
Mitochondrial complex II deficiency
Mitochondrial trifunctional protein deficiency
Carnitine palmitoyltransferase II deficiency
Glutathione synthetase deficiency
Carnitine-acylcarnitine translocase deficiency
Carnitine palmitoyltransferase I deficiency
N-Acetylglutamate synthase deficiency
Acyl-CoA oxidase deficiency