Diagnosis of inherited<unk> , relies heavily on a patient's medical history, family history of bleeding issues, and lab exams performed by a hematologist. A physical examination by a general physician should also be performed in order to determine whether the condition is congenital or acquired, as well as ruling out other possible conditions with similar symptoms. For acquired forms, information must be taken regarding current diseases and medications taken by the patient, if applicable. Lab tests that are performed to determine diagnosis: # Factor assays: To observe the performance of specific factors (II) to identify missing/poorly performing factors. These lab tests are typically performed first in order to determine the status of the factor. # Prothrombin blood test: Determines if patient has deficient or low levels of Factor II. # Vitamin K1 test: Performed to evaluate bleeding of unknown causes, nosebleeds, and identified bruising. To accomplish this, a band is wrapped around the patient's arm, 4 inches above the superficial vein site in the elbow pit. The vein is penetrated with the needle and amount of blood required for testing is obtained. Decreased vitamin K levels are suggestive of<unk> . However, this exam is rarely used as a prothrombin blood test is performed beforehand.
Hypoprothrombinemia
Hypodysfibrinogenemia
Dysfibrinogenemia
Hyperprothrombinemia
Hyperhomocysteinemia
Cryofibrinogenemia
Factor VII deficiency
Factor XIII deficiency