<unk> , or<unk> -Van Bogaert-Bertrand disease, is a rare and fatal autosomal recessive degenerative disorder that causes progressive damage to nerve cells and loss of white matter in the brain. It is one of the most common degenerative cerebral diseases of infancy. It is caused by a deficiency of the enzyme aminoacylase 2, and is one of a group of genetic diseases referred to as leukodystrophies. It is characterized by degeneration of myelin in the phospholipid layer insulating the axon of a neuron and is associated with a gene located on human chromosome 17.
Canavan disease
Menkes disease
Akureyri disease
CADASIL
White dot syndromes
Keshan disease
Farber disease
Familial British dementia