IgE-mediated eosinophil production is induced by compounds released by basophils and mast cells, including<unk> hemotactic factor of anaphylaxis, leukotriene B4 and serotonin mediated release of eosinophil granules occur, complement complex (C5-C6-C7), interleukin 5, and histamine (though this has a narrow range of concentration). Harm resulting from untreated<unk>  potentially varies with cause. During an allergic reaction, the release of histamine from mast cells causes vasodilation which allows eosinophils to migrate from the blood and localize in affected tissues. Accumulation of eosinophils in tissues can be significantly damaging. Eosinophils, like other granulocytes, contain granules (or sacs) filled with digestive enzymes and cytotoxic proteins which under normal conditions are used to destroy parasites but in<unk>  these agents can damage healthy tissues. In addition to these agents, the granules in eosinophils also contain inflammatory molecules and cytokines which can recruit more eosinophils and other inflammatory cells to the area and hence amplify and perpetuate the damage. This process is generally accepted to be the major inflammatory process in the pathophysiology of atopic or allergic asthma.
medical diagnosis of Eosinophilic granulomatosis with polyangiitis
symptom of Eosinophilic granulomatosis with polyangiitis
medical cause of Bronchiolitis obliterans
complications of Melioidosis
complications of Behçet's disease
complications of Rheumatic fever
complications of Idiopathic pulmonary fibrosis
medical cause of Rheumatic fever