As the<unk>  are rare conditions, with a wide range of potential symptoms and complications in their clinical expression, diagnosis can be complex. Most research and literature only assess isolated cases for commonalities. Diagnosis may be made upon emergency presentation. According to a study of 15 cases of<unk>  the diagnosis was mostly clinical; The most common clinical expression was the nevus anemicus, or paler patches of skin, which was present in 50% of cases and Café-au-lait spots and depigmentation were also found to be common distinguishing characteristics in diagnosis. A clinical trial found that an estimated 50% of patients with<unk>  have systemic symptoms and that neurological conditions developed in the first few months of life, if at all. The varied abnormalities present in different patients caused by the<unk>  are difficult to determine, in different syndromes. The most common ocular abnormality has been proven to be ocular melanosis, a congenital eye disease. New clinical findings continue to emerge surrounding potential abnormalities as a result of these conditions.
Phakomatosis
Lipodermatosclerosis
Porokeratosis
Hypodermyasis
Universal angiomatosis
Verruciform xanthoma
Boomerang dysplasia
Granulomatous slack skin