<unk>  <unk>  or<unk><unk>  abnormal pain sensitivity, also called paradoxical<unk> , is generalized pain caused by the long-term use of<unk> s such as morphine, oxycodone, and methadone.<unk>  is not necessarily confined to the original affected site. This means that if the person was originally taking<unk> s due to lower back pain, when<unk>  appears, the person may experience pain in the entire body, instead of just in the lower back. Over time, individuals taking<unk> s can also develop an increasing sensitivity to noxious stimuli, even evolving a painful response to previously non-noxious stimuli (allodynia). This means that if the person originally felt pain from twisting or from sitting too long, the person might now additionally experience pain from a light touch or from raindrops falling on the skin.<unk>  differs from drug tolerance, although it can be difficult to tell the two conditions apart.<unk>  can often be treated by gradually tapering the<unk>  dose and replacing<unk> -based pain care with other pain management medications and techniques or by<unk>  rotation.
Opioid-induced hyperalgesia
Nociplastic pain
Hypoalgesic effect of swearing
Central pain syndrome
Psychogenic pain
Neurogenic inflammation
Neuraxial blockade
Neuropathic pain