<unk>  is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and<unk>  may occur as an adverse reaction to treatment of other conditions. In general, deliberately induced<unk>  is performed to prevent the body from rejecting an organ transplant. Additionally, it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, or Crohn's disease. This is typically done using medications, but may involve surgery (splenectomy), plasmapheresis, or radiation. A person who is undergoing<unk> , or whose immune system is weak for some other reasons (chemotherapy or HIV), is said to be immunocompromised.
Immunosuppression
Adverse reaction to biologic agents
Immunoproliferative disorder
Radiation damage
Paraneoplastic syndrome
Ergogenic use of anabolic steroids
Myeloproliferative neoplasm
Monoclonal gammopathy