<unk>  occurs when thermoregulation is overwhelmed by a combination of excessive metabolic production of<unk>  (exertion), excessive<unk>  in the physical environment, and insufficient or impaired<unk>  loss, resulting in an abnormally high body temperature. Substances that inhibit cooling and cause dehydration such as alcohol, stimulants, medications, and age-related physiological changes predispose to so-called "classic" or non-exertional<unk>  (NEHS), most often in elderly and infirm individuals in summer situations with insufficient ventilation. Exertional<unk>  Exertional<unk>  (EHS) can happen in young people without health problems or medications most often in athletes, outdoor laborers, or military personnel engaged in strenuous hot-weather activity or in first responders wearing heavy personal protective equipment. In environments that are not only hot but also humid, it is important to recognize that humidity reduces the degree to which the body can cool itself by perspiration and evaporation. For humans and other warm-blooded animals, excessive body temperature can disrupt enzymes regulating biochemical reactions that are essential for cellular respiration and the functioning of major organs. Cars When the outside temperature is , the temperature inside a car parked in direct sunlight can quickly exceed . Young children or elderly adults left alone in a vehicle are at particular risk of succumbing to<unk> .<unk>  in children and in the elderly can occur within minutes, even if a car window is opened slightly." As these groups of individuals may not be able to open car doors or to express discomfort verbally (or audibly, inside a closed car), their plight may not be immediately noticed by others in the vicinity. In 2018, 51 children in the United States died in hot cars, more than the previous high of 49 in 2010. Dogs are even more susceptible than humans to<unk>  in cars, as they cannot produce whole-body sweat to cool themselves. Leaving the dog at home with plenty of water on hot days is recommended instead, or, if a dog must be brought along, it can be tied up in the shade outside the destination and provided with a full water bowl.
Heat stroke
Neuroleptic malignant syndrome
Shark attack
Serotonin syndrome  Serotonin syndrome  1
Dry Drowning
Lightning strike
Spinal shock
Drowning