Early signs of melanoma are changes to the shape or color of existing moles or, in the case of nodular melanoma, the appearance of a new lump anywhere on the skin. At later stages, the mole may itch, ulcerate, or bleed. Early signs of melanoma are summarized by the mnemonic "ABCDEF": *Asymmetry *Borders (irregular with edges and corners) *Colour (variegated) *Diameter (greater than , about the size of a pencil eraser) *Evolving over time This classification does not apply to nodular melanoma, which has its own classifications: *Elevated above the skin surface *Firm to the touch *Growing Metastatic melanoma may cause nonspecific paraneoplastic symptoms, including loss of appetite, nausea, vomiting, and fatigue. Metastasis (spread) of early melanoma is possible, but relatively rare; less than a fifth of melanomas diagnosed early become metastatic. Brain metastases are particularly common in patients with metastatic melanoma. It can also spread to the liver, bones, abdomen, or distant lymph nodes.
types of Anal cancer
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types of Skin cancer
medical cause of Stomach cancer
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symptom of Appendix cancer
medical cause of Mucosal melanoma