Most patients do not require medical intervention. Nevertheless, the rare chances of life-threatening acute drop in hemoglobin are always there and in which are deemed to develop hypovolemic shock and cardiac failure due to severe anemia, and to be complicated by acute tubular necrosis as a result of hemoglobinuria over the aftermath. In addition to the rarely happened severe anemia and complications, prognosis of DLHA is deemed to be very good. Most patients recovered spontaneously not longer than 30 days since the disease onset. Long-term mild hemolytic anemia has been reported for several children who were in the likelihood of recurrence on exposure to any kind of cold or with illness. Case studies of those with recurrent DLHA suggest that repeated episodes of the hemolysis should not be regarded as false positive because the chances do truly exist when the patient has a D-L antibody to an antigen other than anti-P. Chronic syphilis-associated DLHA resolves when the underlying disease receives appropriate treatment.
Donath–Landsteiner hemolytic anemia
Warm antibody autoimmune hemolytic anemia
Cold autoimmune hemolytic anemia
symptom of Congenital dyserythropoietic anemia
medical cause of Hemolytic anemia
Sickle cell-beta thalassemia
Twin anemia-polycythemia sequence
Hughes–Stovin syndrome