<unk>  <unk>  or<unk> ase-producing<unk>  (CPE) are Gram-negative bacteria that are resistant to the<unk>  class of antibiotics, considered the drugs of last resort for such infections. They are resistant because they produce an enzyme called a<unk> ase that disables the drug molecule. The resistance can vary from moderate to severe.<unk>  are common commensals and infectious agents. Experts fear<unk>  as the new "superbug". The bacteria can kill up to half of patients who get bloodstream infections. Tom Frieden, former head of the Centers for Disease Control and Prevention has referred to<unk>  as "nightmare bacteria". Examples of enzymes found in certain types of<unk>  are KPC (Klebsiella pneumoniae<unk> ase) and NDM (New Delhi Metallo-beta-lactamase). KPC and NDM are enzymes that break down<unk> s and make them ineffective. Both of these enzymes, as well as the enzyme VIM (Verona Integron-Mediated Metallo-β-lactamase) have also been reported in Pseudomonas.
Carbapenem-resistant enterobacteriaceae
Vancomycin-resistant Enterococcus
Shigatoxigenic and verotoxigenic Escherichia coli
Vancomycin-resistant Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus
Rapid growing mycobacterium
Isolated levocardia
Enteroinvasive Escherichia coli