<unk>  exists on a continuum of different attack frequencies and associated levels of disability." For those with occasional, episodic<unk> , a "proper combination of drugs for prevention and treatment of<unk>  attacks" can limit the disease's impact on patients' personal and professional lives. But fewer than half of people with<unk>  seek medical care and more than half go undiagnosed and undertreated. "Responsive prevention and treatment of<unk>  is incredibly important" because evidence shows "an increased sensitivity after each successive attack, eventually leading to chronic daily<unk>  in some individuals." Repeated<unk>  results in "reorganization of brain circuitry," causing "profound functional as well as structural changes in the brain." "One of the most important problems in clinical<unk>  is the progression from an intermittent, self-limited inconvenience to a life-changing disorder of chronic pain, sensory amplification, and autonomic and affective disruption. This progression, sometimes termed chronification in the<unk>  literature, is common, affecting 3% of<unk> urs in a given year, such that 8% of<unk> urs have chronic<unk>  in any given year." Brain imagery reveals that the electrophysiological changes seen during an attack become permanent in people with chronic<unk> ; "thus, from an electrophysiological point of view, chronic<unk>  indeed resembles a never-ending<unk>  attack." Severe<unk>  ranks in the highest category of disability, according to the World Health Organization, which uses objective metrics to determine disability burden for the authoritative annual Global Burden of Disease report. The report classifies severe<unk>  alongside severe depression, active psychosis, quadriplegia, and terminal-stage cancer.<unk>  with aura appears to be a risk factor for ischemic stroke doubling the risk. Being a young adult, being female, using hormonal birth control, and smoking further increases this risk. There also appears to be an association with cervical artery dissection.<unk>  without aura does not appear to be a factor. The relationship with heart problems is inconclusive with a single study supporting an association.<unk>  does not appear to increase the risk of death from stroke or heart disease. Preventative therapy of<unk> s in those with<unk>  with aura may prevent associated strokes. People with<unk> , particularly women, may develop higher than average numbers of white matter brain lesions of unclear significance.
Migraine
Cluster headache
Lupus headache
Subarachnoid hemorrhage
Tension headache
Sinusitis
External compression headache
Brain tumor