Standard classification The lysosomal storage diseases are generally classified by the nature of the primary stored material involved, and can be broadly broken into the following: (ICD-10 codes are provided where available) * (E75) Lipid storage disorders * Sphingolipidoses, including Gaucher's and Niemann–Pick diseases (E75.0-E75.1) * Gangliosidosis (including Tay–Sachs disease (E75.2) *<unk> es * (E76.0) Mucopolysaccharidoses, including Hunter syndrome and Hurler disease * (E77) Glycoprotein storage disorders * (E77.0-E77.1) Mucolipidoses Also, glycogen storage disease type II (Pompe disease) is a defect in lysosomal metabolism as well, although it is otherwise classified into E74.0 in ICD-10. Cystinosis is an lysosomal storage disease characterized by the abnormal accumulation of the amino acid cystine. By type of defect protein Alternatively to the protein targets, lysosomal storage diseases may be classified by the type of protein that is deficient and is<unk> ng buildup. Type of defect protein Disease examples Deficient protein Lysosomal enzymes primarily Tay–Sachs disease, I-cell disease, Sphingolipidoses (e.g., Krabbe disease, gangliosidosis: Gaucher, Niemann–Pick disease and glycolipids:<unk><unk> , Lysosomal acid lipase deficiency Various Posttranslational modification of enzymes Multiple sulfatase deficiency Multiple sulfatases Membrane transport proteins Mucolipidosis type II and IIIA N-acetylglucosamine-1-phosphate transferase Enzyme protecting proteins Galactosialidosis Cathepsin A Soluble nonenzymatic proteins GM2-AP deficiency, variant AB, Niemann–Pick disease, type C2 GM2-AP, NPC2 Transmembrane proteins SAP deficiency Sphingolipid activator proteins Niemann–Pick disease, type C1 NPC1 Salla disease Sialin Unless else specified in boxes, then the applicable reference is: Lysosomal storage disorders Lysosomal storage diseases include: * Sphingolipidoses * Ceramidase * Farber disease * Krabbe disease * Infantile onset * Late onset * Galactosialidosis * Gangliosides: gangliosidoses * Alpha-galactosidase * Fabry disease (alpha-galactosidase A) * Schindler disease (alpha-galactosidase B) * Beta-galactosidase / GM1 gangliosidosis * Infantile * Juvenile * Adult / chronic * GM2 gangliosidosis * AB variant * Activator deficiency * Sandhoff disease * Infantile * Juvenile * Adult onset * Tay–Sachs * Juvenile hexosaminidase A deficiency * Chronic hexosaminidase A deficiency * Glucocerebroside * Gaucher disease * Type I * Type II * Type III * Sphingomyelinase * Lysosomal acid lipase deficiency * Early onset * Late onset * Niemann–Pick disease * Type A * Type B * Sulfatidosis *<unk><unk>  * Saposin B deficiency * Multiple sulfatase deficiency Mucopolysaccharidoses * Type I * MPS I Hurler syndrome * MPS I S Scheie syndrome * MPS I H-S Hurler–Scheie syndrome * Type II (Hunter syndrome) * Type III (Sanfilippo syndrome) * MPS III A (Type A) * MPS III B (Type B) * MPS III C (Type C) * MPS III D (Type D) * Type IV (Morquio) * MPS IVA (Type A) * MPS IVB (Type B) * Type VI (Maroteaux–Lamy syndrome) * Type VII (Sly syndrome) * Type IX (hyaluronidase deficiency) Mucolipidosis * Type I (sialidosis) * Type II (I-cell disease) * Type III (pseudo-Hurler polydystrophy / phosphotransferase deficiency) * Type IV (mucolipidin 1 deficiency) Lipidoses * Niemann–Pick disease * type C * Type D * Neuronal ceroid lipofuscinoses * Type 1 Santavuori–Haltia disease / infantile NCL (CLN1 PPT1) * Type 2 Jansky–Bielschowsky disease / late infantile NCL (CLN2/LINCL TPP1) * Type 3 Batten–Spielmeyer–Vogt disease / juvenile NCL (CLN3) * Type 4 Kufs disease / adult NCL (CLN4) * Type 5 Finnish Variant / late infantile (CLN5) * Type 6 Late infantile variant (CLN6) * Type 7 CLN7 * Type 8 Northern epilepsy (CLN8) * Type 8 Turkish late infantile (CLN8) * Type 9 German/Serbian late infantile (unknown) * Type 10 Congenital cathepsin D deficiency (CTSD) * Wolman disease Oligosaccharide * Alpha-mannosidosis * Beta-mannosidosis * Aspartylglucosaminuria * Fucosidosis Lysosomal transport diseases * Cystinosis * Pycnodysostosis * Salla disease / sialic acid storage disease * Infantile free sialic acid storage disease Glycogen storage diseases * Type II Pompe disease * Type IIb Danon disease Other * Cholesteryl ester storage disease Lysosomal disease
medical cause of Metachromatic leukodystrophy
symptom of Pantothenate kinase-associated neurodegeneration
medical cause of Polyneuropathy
medical cause of Parkinsonism
symptom of Spinocerebellar ataxia type 1
complications of Friedreich's ataxia
symptom of Bannayan–Riley–Ruvalcaba syndrome
symptoms of Rabies