<unk>  can be successfully controlled with early diagnosis and aggressive treatment including albumin infusions, nephrectomy, and medications. Affected children have rapid decline in kidney function resulting in end-stage renal disease within the first years of life, and require treatment with dialysis and kidney transplantation. Most children live fairly normal life post-transplant but will spend significant time hospitalised pre-transplant and have numerous surgeries to facilitate treatment. Kidney transplantation outcomes for children with<unk>  are similar to those of other patient groups.<unk><unk>  typically does not reoccur following kidney transplantation, however recurrences have been seen in children with NPHS1 mutations who develop anti-nephrin antibodies. Due to the protein (albumin) losses many patients have reduced muscle tone and may experience delays in certain physical milestones such as sitting, crawling and walking. Similarly many patients experience growth delays due to protein loss. Delays vary from mild to significant but most patients experience growth spurts once they receive their transplanted kidney. Physical therapy may be useful for the child to strengthen muscle tone. Children who have a history of stroke from thrombotic complications can have neurologic delays. Undiagnosed cases are often fatal in the first year due to blood clots, infections or other complications.
Congenital nephrotic syndrome
Cystic kidney disease
Medullary cystic kidney disease
Glomerulocystic kidney disease
Juvenile nephronophthisis
Malarial nephropathy
Polycystic kidney disease
Transplant glomerulopathy