Dissection of a cadaver, 15th-century painting The<unk>  extends from the earliest examinations of sacrificial victims to the sophisticated analyses of the body performed by modern<unk> sts and scientists. Written descriptions of human organs and parts can be traced back thousands of years to ancient Egyptian papyri, where attention to the body was necessitated by their highly elaborate burial practices. Theoretical considerations of the structure and function of the human body did not develop until far later, in Ancient Greece. Ancient Greek philosophers, like Alcmaeon and Empedocles, and ancient Greek doctors, like Hipprocrates and his school, paid attention to the causes of life, disease, and different functions of the body. Aristotle advocated dissection of animals as part of his program for understanding the causes of biological forms. During the Hellenistic Age, dissection and vivesection of human beings took place for the first time in the work of Herophilos and Erasistratus.<unk> cal knowledge in antiquity would reach its apex in the person of Galen, who made important discoveries through his medical practice and his dissections of monkeys, oxen, and other animals. The development of the study of<unk>  gradually built upon concepts that were present in Galen's work, which was a part of the traditional medical curriculum in the Middle Ages. The Renaissance brought a reconsideration of classical medical texts, and<unk> cal dissections became once again fashionable for the first time since Galen. Important<unk> cal work was carried out by Mondino de Luzzi, Berengario da Carpi, and Jacques Dubois, culminating in Andreas Vesalius's seminal work De Humani Corporis Fabrica (1543). An understanding of the structures and functions of organs in the body has been an integral part of medical practice and a source for scientific investigations ever since.
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