Fulminant infection from meningococcal bacteria in the bloodstream is a medical emergency and requires emergent treatment with vasopressors, fluid resuscitation, and appropriate antibiotics. Benzylpenicillin was once the drug of choice with chloramphenicol as a good alternative in allergic patients. Ceftriaxone is an antibiotic commonly employed today. Hydrocortisone can sometimes reverse the adrenal insufficiency. Amputations, reconstructive surgery, and tissue grafting are sometimes needed as a result of tissue necrosis (typically of the extremities) caused by the infection.
Waterhouse–Friderichsen syndrome
Woodhouse–Sakati syndrome
Michels Caskey syndrome
Johanson–Blizzard syndrome
Hashimoto's encephalopathy
Wellens' syndrome
Hemolytic–uremic syndrome
Primrose syndrome