<unk>  is used in addition to levodopa and carbidopa for people with Parkinson's disease to treat the signs and symptoms of end-of-dose "wearing-off." "Wearing-off" is characterized by the re-appearance of both motor and non-motor symptoms of Parkinson's disease occurring towards the end of a previous levodopa and carbidopa dose. In clinical trials,<unk>  has not been shown to slow progression or reverse Parkinson's disease.<unk>  is an orally active drug that can be taken with or without food. Pregnancy and breastfeeding Pregnancy category C: risk is not ruled out. Although there have been animal studies that showed that<unk>  was excreted into maternal rat milk, there have been no studies with human breast milk. Caution is advised for mothers taking<unk>  while breastfeeding or during pregnancy. Children<unk>  safety and efficacy have not been assessed in infants or children. Liver problems Biliary excretion is the major route of excretion for<unk> . People with liver dysfunction may require additional caution and more frequent liver function monitoring while taking<unk> . Kidney problems There are no significant considerations for people with poor kidney function taking<unk> .
Entacapone
Rivastigmine
Influenzanet
Nabilone
Tasimelteon
Droxidopa
Ixabepilone
Zaleplon