There have been reported cases of a child having both atypical teratoid<unk><unk> s in the brain as well as<unk><unk> s of the kidney. Weeks and associates reported on 111 renal<unk>  cases of which 13.5% also had a central nervous system<unk> y. It has been hypothesized that a germline INI mutation may predispose a child to these<unk> s. There have been some references in the literature alluding to a new diagnosis called<unk>  predisposition syndrome related to the gene hSNF5/INI1. These<unk> s have been associated with mutations in the SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) located on the long arm of chromosome 22 (22q11) and transcription activator BRG1/ATP-dependent chromatin remodeler (SMARCA4) located on the short arm of chromosome 19 (19p13.2).<unk><unk> s in kidney and brain Considerable debate has been focused on whether atypical teratoid<unk> <unk> s are the same as<unk><unk> s of the kidney (i.e., just extrarenal<unk> s). Recognition that both CNS atypical teratoid/rhabdoid<unk> s and<unk> s have deletions of the INI1 gene in chromosome 22 indicates that<unk><unk> s of the kidney and brain are identical or closely related entities, although the CNS variant tends to have its mutations on Taxon 9 and<unk> s elsewhere. This observation is not surprising because<unk><unk> s at both locations possess similar histologic, clinical, and demographic features. Moreover, 10-15% of patients with<unk> s have synchronous or metachronous brain<unk> s, many of which are second primary<unk> s. This similarity excludes composite<unk><unk> s, which occur mainly in adults.
Malignant rhabdoid tumour
Primitive neuroectodermal tumor
Atypical teratoid rhabdoid tumor
Endodermal sinus tumor
Pediatric ependymoma
Ameloblastoma
Embryonal rhabdomyosarcoma
Neurothekeoma