The distinctive characteristics of<unk>  include severe bone and joint problems and very severe hearing loss. This disorder affects the epiphyses, the parts of the bone where growth occurs. People with the condition are often shorter than average because the bones in their arms and legs are unusually short. Other skeletal signs include enlarged joints, short hands and fingers, and flat bones of the spine (vertebrae). People with the disorder often experience back and joint pain, limited joint movement, and arthritis that begins early in life. Severe high-tone hearing loss is common. Typical facial features include protruding eyes; a sunken nasal bridge; an upturned nose with a large, rounded tip; and a small lower jaw. Some affected infants are born with an opening in the roof of the mouth, which is called a cleft palate.
Otospondylomegaepiphyseal dysplasia
Spondylo-meta-epiphyseal dysplasia
Metaphyseal dysplasia
Craniometaphyseal dysplasia
Multiple epiphyseal dysplasia
Achondroplasia
Craniodiaphyseal dysplasia
Spondyloepimetaphyseal dysplasia