+<unk>  Site Ki (nM) 29 33 531 5-HT2A 1,685 5-HT2B 330 5-HT2C 56 The mechanism of action of<unk>  and its analgesic effects are not well understood, although inhibition of the reuptake of serotonin, norepinephrine, and to a lesser extent dopamine (that is, acting as an ) is thought to be involved. It also reduces glutamate signaling via modulating sodium and calcium channels.
Nefopam
Setiptiline
Lofexidine
Ivabradine
Fenoldopam
Verapamil
Alvimopan
Iofetamine 