It may cause serious health problems when overdosed. Signs and symptoms of adverse effects may include any or several of the following: convulsions, respiratory depression (slow or stopped breathing), dilated eye pupils, nystagmus (rapid side-to-side eye movements), erythema (flushed skin), gastrointestinal constipation, nausea, vomiting, paralytic ileus, tachycardia (rapid pulse), drowsiness and hallucinations. Symptoms of toxicity may take up to 12 hours to appear. Treatment of overdose must be initiated immediately after diagnosis and may include the following: ingestion of activated charcoal, laxative and a counteracting medication (narcotic antagonist).
Atropine/diphenoxylate
Desloratadine/pseudoephedrine
Pseudoephedrine/loratadine
Cinnarizine/dimenhydrinate
Sodium nitrite/sodium thiosulfate
Oxycodone/naloxone
Octatropine methylbromide
Fentanyl/fluanisone