Reported cases WHO-Region 1980 1990 2000 2005 2010 2015 2018 2019 2020 African Region 1,240,993 481,204 520,102 316,219 199,174 52,758 125,426 618,595 115,369 Region of the Americas 257,790 218,579 1,754 85 247 611 16,714 21,971 1,548 Eastern Mediterranean Region 341,624 59,058 38,592 15,069 10,072 21,418 64,764 18,458 6,122 European Region 492,660 185,818 37,421 37,338 30,625 25,957 89,148 106,130 10,935 South-East Asia Region 199,535 224,925 78,558 88,973 54,228 48,888 34,741 29,389 9,389 Western Pacific Region 1,319,640 155,490 177,052 128,017 49,460 65,176 29,503 78,479 6,599 Worldwide 3,852,242 1,325,074 853,479 585,701 343,806 214,808 360,296 873,022 149,962 In 2011, the WHO estimated that there were about 158,000 deaths caused by<unk> . This is down from 630,000 deaths in 1990. In developed countries, death occurs in 1 to 2 cases out of every 1,000 (0.1% - 0.2%). Death from<unk>  was reported in approximately 0.2% of the cases in the United States from 1985 through 1992. In populations with high levels of malnutrition and a lack of adequate healthcare, mortality can be as high as 10%. Increased immunization has led to an estimated 78% drop in<unk>  deaths among UN member states. Even in countries where vaccination has been introduced, vaccination rates may remain low due to parents choosing not to have their children vaccinated. In Ireland, vaccination was introduced in 1985. There were 99,903 cases that year. Within two years, the number of cases had fallen to 201, but this fall was not sustained.<unk>  is a leading cause of vaccine-preventable childhood mortality. Worldwide, the fatality rate has been significantly reduced by a vaccination campaign led by partners in the<unk>  Initiative: the American Red Cross, the United States Centers for Disease Control and Prevention (CDC), the United Nations Foundation, UNICEF and the WHO. Globally,<unk>  fell 60% from an estimated 873,000 deaths in 1999 to 345,000 in 2005. Estimates for 2008 indicate deaths fell further to 164,000 globally, with 77% of the remaining<unk>  deaths in 2008 occurring within the Southeast Asian region. In 2006–07 there were 12,132 cases in 32 European countries: 85% occurred in five countries: Germany, Italy, Romania, Switzerland and the UK. 80% occurred in children and there were 7 deaths. Five out of six WHO regions have set goals to eliminate<unk> , and at the 63rd World Health Assembly in May 2010, delegates agreed a global target of a 95% reduction in<unk>  mortality by 2015 from the level seen in 2000, as well as to move towards eventual eradication. However, no specific global target date for eradication has yet been agreed to as of May 2010. On January 22, 2014, the World Health Organization and the Pan American Health Organization declared and certified Colombia free of the<unk>  while becoming the first Latin American country to abolish the infection within its borders. Cases reported in the first three months of 2019 were 300% higher than in the first three months of 2018, with outbreaks in every region of the world, even in countries with high overall vaccination coverage where it spread among clusters of unvaccinated people. In April 2020, the WHO indicated that many countries had started suspending their<unk>  vaccination programs due to the impact of the COVID-19 pandemic. It is projected that 117 million children will be at risk of infection.
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