The<unk>  (ELITE) was a large randomized controlled<unk>  that assessed the timing hypothesis that menopausal hormone therapy in<unk>  but not<unk>  menopause would improve cardiovascular outcomes.
Early versus Late Intervention Trial with Estradiol
Study of Tamoxifen and Raloxifene
Age adjustment
Bioidentical hormone replacement therapy
Chronotherapy 
Comparison of bicalutamide with other antiandrogens
Transgender hormone therapy
Androgen replacement therapy