<unk> , sold under the trade name Midamor among others, is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver.<unk>  is classified as a potassium-sparing diuretic.<unk>  is often used together with another diuretic, such as a thiazide or loop diuretic. It is taken by mouth. Onset of action is about two hours and it lasts for about a day. Common side effects include high blood potassium, vomiting, loss of appetite, rash, and headache. The risk of high blood potassium is greater in those with kidney problems, diabetes, and those who are older.<unk>  blocks the epithelial sodium channel (ENaC) in the late distal tubule, connecting tubule, and collecting duct of the nephron, which both reduces absorption of sodium ion from the lumen of the nephron and reduces excretion of potassium ion into the lumen.<unk>  was developed in 1967. It is on the World Health Organization's List of Essential Medicines.
Amiloride
Bumetanide
Chlorothiazide
Furosemide
Cyclothiazide
Tolvaptan
Torasemide
Spironolactone