In<unk> , there is mineralization (accumulation of calcium and other minerals) and fragmentation of the elastin-containing fibers in connective tissue, but primarily in the midlaminar layer of the dermis, Bruch's membrane and the midsized arteries. Recent studies have confirmed that<unk>  is a metabolic disease, and that its features arise because metabolites of vitamin K cannot reach peripheral tissues. Low levels of PPi cause mineralization in peripheral tissues.
Pseudoxanthoma elasticum
Nodular lichen myxedematosus
Keratosis pilaris
Erythrokeratodermia variabilis
Keratosis pilaris atrophicans
Dystrophic calcinosis cutis
Granuloma annulare
Dermatosis neglecta