<unk>  is generally well tolerated with low discontinuation rates among the HIV and chronic hepatitis B population. There are no contraindications for use of this drug. The most commonly reported side effects due to use of<unk>  were dizziness, nausea, and diarrhea. Other adverse effects include depression, sleep disturbances, headache, itching, rash, and fever. The US boxed warning cautions potential onset of lactic acidosis or liver damage due to use of<unk> . Long term use of<unk>  is associated with nephrotoxicity and bone loss. Presentation of nephrotoxicity can appear as Fanconi syndrome, acute kidney injury, or decline of glomerular filtration rate (GFR). Discontinuation of<unk>  can potentially lead to reversal of renal impairment. Nephrotoxicity may be due to proximal tubules accumulation of<unk>  leading to elevated serum concentrations.
Tenofovir disoproxil
Tenofovir alafenamide
Rilpivirine
Brincidofovir
Daclatasvir
Cidofovir
Telbivudine
Sorivudine