Mild and transient elevations in<unk> ctate have limited impact on mortality, whereas sustained and severe<unk> ctate elevations are associated with a high mortality. The mortality of<unk>  in people taking metformin was previously reported to be 50%, but in more recent reports this was closer to 25%.
Lactic acidosis
Metabolic acidosis
Acidosis
Metabolic alkalosis
Azotemia
Hyperammonemia
Alkalosis
Hypercapnia