Micrograph of a<unk>  with the characteristic changes (parakeratosis, koilocytes, papillomatosis). H&E stain. The diagnosis of<unk> s is most often made visually, but may require confirmation by biopsy in some cases. Smaller<unk> s may occasionally be confused with molluscum contagiosum.<unk> s, histopathologically, characteristically rise above the skin surface due to enlargement of the dermal papillae, have parakeratosis and the characteristic nuclear changes typical of HPV infections (nuclear enlargement with perinuclear clearing). DNA tests are available for diagnosis of high-risk HPV infections. Because<unk> s are caused by low-risk HPV types, DNA tests cannot be used for diagnosis of<unk> s or other low-risk HPV infections. Some practitioners use an acetic acid solution to identify smaller<unk> s ("subclinical lesions"), but this practice is controversial. Because a diagnosis made with acetic acid will not meaningfully affect the course of the disease, and cannot be verified by a more specific test, a 2007 UK guideline advises against its use.
Genital wart
Skin tag
Genu recurvatum
Condylomata lata
Trichostasis spinulosa
Molluscum contagiosum
Bifid penis
Squamous cell carcinoma