The symptoms and signs of<unk>  were first described in 1827 by the English physician Richard<unk> , after whom the<unk>  was named. In his Reports of Medical Cases, he described 25 cases of dropsy (edema) which he attributed to kidney<unk> . Symptoms and signs included: inflammation of serous membranes, hemorrhages, apoplexy, convulsions, blindness and coma. Many of these cases were found to have albumin in their urine (detected by the spoon and candle-heat coagulation), and showed striking morbid changes of the kidneys at autopsy. The triad of dropsy, albumin in the urine and kidney<unk>  came to be regarded as characteristic of<unk> . Subsequent work by<unk>  and others indicated an association with cardiac hypertrophy, which<unk>  attributed to stimulation of the heart. Subsequent work by Frederick Akbar Mahomed showed that a rise in blood pressure could precede the appearance of albumin in the urine, and the rise in blood pressure and increased resistance to flow was believed to explain the cardiac hypertrophy. It is now known that<unk>  is caused by a wide and diverse range of kidney<unk> s; thus, the term<unk>  is retained strictly for historical application. The<unk>  was diagnosed frequently in diabetic patients; at least some of these cases would probably correspond to a modern diagnosis of diabetic nephropathy.
Bright's disease
Darier's disease
Tornwaldt's disease
Dent's disease
Lev's disease
Borna disease
Minor's disease
Blount's disease