Drug reactions have been reported to cause 80–95% of<unk>  cases. The drugs most often implicated in<unk>  are: * antibiotics * sulfonamides (sulfamethoxazole, sulfadiazine, sulfapyridine) * beta-lactams (cephalosporins, penicillins, carbapenems) * nonsteroidal anti-inflammatory drugs * allopurinol * antimetabolites (methotrexate) * antiretroviral drugs (nevirapine) * corticosteroids * anxiolytics (chlormezanone) * anticonvulsants (phenobarbital, phenytoin, carbamazepine, lamotrigine, and valproic acid).<unk>  has also been reported to result from infection with Mycoplasma pneumoniae or dengue virus. Contrast agents used in imaging studies as well as transplantation of bone marrow or organs have also been linked to<unk>  development. HIV HIV-positive individuals have 1000 times the risk of developing SJS/TEN compared to the general population. The reason for this increased risk is not clear. Genetics Certain genetic factors are associated with increased risk of<unk> . For example, certain HLA-types such as, HLA-B*1502, HLA-A*3101, HLA-B*5801, and HLA‐B*57:01 have been seen to be linked with<unk>  development when exposed to specific drugs.
Toxic epidermal necrolysis
Staphylococcal scalded skin syndrome
Poikiloderma vasculare atrophicans
Chickenpox
Streptococcal intertrigo
Skin condition
Cutaneous lupus mucinosis
Staphylococcal infection