<unk>  has two mechanism of action depending on what conformation (isomer) is at in the system in which it will work. Isomer A functions as a protein synthesis inhibitor. It binds to the<unk> all 16S rRNA of the 30S subunit of the bacterial ribosome irreversibly, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This leads to codon misreading, eventual inhibition of protein synthesis and ultimately death of microbial cells through mechanisms that are still not understood. Speculation on this mechanism indicates that the binding of the molecule to the 30S subunit interferes with 30S subunit association with the mRNA<unk> and. This results in an unstable ribosomal-mRNA complex, leading to a frameshift mutation and premature stopping of protein synthesis; leading to cell death. As human and bacterial both have ribosomes,<unk>  has significant side effects in human cells. At low concentrations, however,<unk>  only inhibits growth of the bacteria by inducing prokaryotic ribosomes to misread mRNA.<unk>  isomer B is a peptidoglycan synthesis inhibitor much like lysozyme. It binds to the glycosidic linkages and breaks them through a SN2 mechanism. This leads to bacterial cell walls' integrity being compromised, ultimately resulting in death of microbial cells.<unk>  is an antibiotic that inhibits both Gram-positive and Gram-negative bacteria, and is therefore a useful broad-spectrum antibiotic.
Streptomycin
Amikacin
Doxycycline
Secnidazole
Safinamide
Pyrazinamide
Anisomycin
Tetracycline