<unk>  is a type II topoisomerase inhibitor; it disrupts DNA synthesis and DNA repair in both healthy cells and cancer cells by intercalation between DNA bases. It is also classified as an antibiotic. Human topoisomerase II beta in complex with DNA and<unk> . PDB entry . Detail showing<unk>  (spheres) intercalated with DNA.
Mitoxantrone
Vincristine
Ifosfamide
Clofarabine
Doxorubicin
Fludarabine
Nelarabine
Carmustine