Estrogens are produced by functioning tumours, and the clinical presentation depends on the patient's age and sex. * Female * If the patient is postmenopausal, she usually presents with abnormal uterine bleeding, and in some cases hemoperitoneum. * If the patient is of reproductive age, she would present with menometrorrhagia. However, in some cases she may stop ovulating altogether. * If the patient has not undergone puberty, early onset of puberty may be seen. * these tumors tend to have late recurrencies ( even after 30 years )
Granulosa cell tumour
Sertoli cell tumour
Leydig cell tumour
Gonadoblastoma
Metanephric adenoma
Germ cell tumor
Sertoli–Leydig cell tumour
Ovarian germ cell tumors