<unk> , also known as derivative 22 syndrome, or der(22) syndrome, is a rare disorder associated with multiple congenital anomalies, including profound intellectual disability, preauricular skin tags or pits, and conotruncal heart defects. It can occur in offspring of carriers of the constitutional chromosomal translocation t(11;22)(q23;q11), owing to a 3:1 meiotic malsegregation event resulting in partial trisomy of chromosomes 11 and 22. An unbalanced translocation between chromosomes 11 and 22 is described as<unk> . It was first described in 1980 by American medical researchers Beverly S.<unk>  and Elaine H. Zackai, and a consortium of European scientists the same year.
Emanuel syndrome
TRIANGLE disease
RIDDLE syndrome
Crigler–Najjar syndrome
CLOVES syndrome
RAPADILINO syndrome
PASLI disease
Woodhouse–Sakati syndrome