Traditional<unk>  adenoma seen under microscopy with H&E stain, showing<unk>  crypts SPS may occur with one of two phenotypes: distal or proximal. The distal phenotype may demonstrate numerous small polyps in the distal colon (sigmoid) and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). Individuals meeting only criterion 3 from 2010 criteria, or only criterion 2 from the 2019 classification, have a distal phenotype have a lower risk of CRC compared with the proximal phenotype.
Serrated polyposis syndrome
Familial adenomatous polyposis
Juvenile polyposis syndrome
MUTYH-associated polyposis
Hereditary nonpolyposis colorectal cancer
Attenuated familial adenomatous polyposis
Peutz–Jeghers syndrome
Ogden syndrome