<unk>  is distinctive, if the health care provider is familiar with it. The diagnosis is then made by the typical acute onset in the weeks following a sore throat or other minor infection, plus evidence of inflammation (raised CRP and/or ESR) and evidence of recent streptococcal infection. To confirm recent streptococcal infection: * Throat culture * Anti-DNAse B titre (peaks at 8–12 weeks after infection) * Anti-streptolysin O titre (peaks at 3–5 weeks) None of these tests are 100% reliable, particularly when the infection was some months previously. Further testing is directed more towards alternative diagnoses and other manifestations of rheumatic fever: * Echocardiography * EEG * Lumbar puncture * Magnetic resonance imaging or computed tomography<unk> an of the brain (alterations in caudate nucleus and putaminal enlargement have been described in some patients)
Sydenham's chorea
Huntington's disease
Benign hereditary chorea
Parkinson-plus syndrome
Wernicke–Korsakoff syndrome
Huntington's disease-like syndrome
X-linked dystonia parkinsonism
Stratton Parker syndrome