<unk> , also known as<unk><unk>  syndrome or tibioperoneal diaphyseal toxopachyosteosis, is a rare disorder characterized by bowing of the lower legs and an abnormal thickening of thinner bone in the leg. The main sign is anterior bowing and posterior cortical thickening of the diaphyses of both the tibiae and fibulae. It is thought to be inherited in an autosomal dominant fashion and is most often bilateral and symmetric in nature. Associated features include dwarfism and mild intellectual disability as well as a process known as tibialization of the fibulae, which involves thickening and enlargement of these bones to an extent resembling the tibiae. The combination of the presence of tibialization of the fibulae, which is highly specific for the disorder, and the absence of laboratory abnormalities, ruling out alternative diagnoses including rickets, essentially confirms the diagnosis.
Weismann-Netter–Stuhl syndrome
Li–Fraumeni syndrome
Wiedemann–Rautenstrauch syndrome
Daentl Townsend Siegel syndrome
Beckwith–Wiedemann syndrome
Prader–Willi syndrome
Simpson–Golabi–Behmel syndrome
Dennie–Marfan syndrome