Interferon beta balances the expression of pro- and anti-inflammatory agents in the brain, and reduces the number of inflammatory cells that cross the blood brain barrier. Overall, therapy with interferon beta leads to a reduction of neuron inflammation. Moreover, it is also thought to increase the production of nerve growth factor and consequently improve neuronal survival. In vitro, interferon beta reduces production of Th17 cells which are a subset of T lymphocytes believed to have a role in the pathophysiology of MS.
Interferon beta-1a
Interferon beta-1b
Peginterferon beta-1a
Peginterferon alfa-2a
Peginterferon alfa-2b
Pegylated interferon
Ropeginterferon alfa-2b
Adalimumab