MPO deficiency is broken down into two categories: primary/congenital and secondary/acquired. Primary MPO deficiency is an autosomal recessive genetic disorder, which is caused by mutations in the<unk>  gene on chromosome 17q23. There are several different known mutations of this gene which all lead to<unk> . Secondary MPO deficiency, on the other hand, occurs in various clinical situations as a result of hematological neoplasm, disseminated cancers, some drugs, iron deficiency, lead intoxication, thrombotic disease, renal transplantation, severe infectious disease, diabetes mellitus, neuronal lipofuscinosis, or pregnancy. Secondary MPO deficiency is typically partial, meaning only a portion of the affected individual’s neutrophils lack functional<unk> .
Myeloperoxidase deficiency
MBL deficiency
Leukocyte adhesion deficiency
Adenosine deaminase deficiency
Adenosine deaminase 2 deficiency
Leukocyte adhesion molecule deficiency
Neutrophil-specific granule deficiency
Primary immunodeficiency