<unk> /CNO is a diagnosis of exclusion. This means that other diseases must be ruled out before the diagnosis can be made. Generally, many tests are required, such as blood tests, x-rays, bone scans, MRI and often a bone biopsy. Classification Due to its inflammatory nature, its<unk>  flares, and its lack of any known pathogen,<unk>  has been reclassified as an autoinflammatory disease. This particular classification encompasses both hereditary types (familial Mediterranean fever, mevalonate kinase deficiency, TNF receptor associated periodic syndrome, cryopyrin-associated periodic syndrome, Blau syndrome, pyogenic sterile arthritis, pyoderma gangrenosum and acne syndrome,<unk>  and multifactorial disorders (Crohn's and Behçet's diseases).<unk>  is no longer considered an autoimmune but rather an inherited, autoinflammatory disease.
Chronic recurrent multifocal osteomyelitis
Neuralgia-inducing cavitational osteonecrosis
Chronic undermining burrowing ulcer
Shoulder injury related to vaccine administration
Skin manifestations of sarcoidosis
Chronic limb threatening ischemia
Intervertebral disc damage and spaceflight
Localized disease