<unk>  is a strategy to reduce the<unk>  of a vaccine to achieve a<unk>  policy goal that is more difficult to achieve with conventional<unk>  approaches, including deploying a vaccine faster in a pandemic, reaching more individuals in the setting of limited healthcare budgets, or minimizing side effects due to the vaccine.<unk>  exploits the nonlinear<unk> -response characteristics of a vaccine: If two persons can be vaccinated instead of one, but each one gets 2/3 of the protective efficacy, there is a net benefit at society scale for reducing the number of infections. If the healthcare budget is limited or only a limited amount of vaccine is available during the early phase of a pandemic, this can make a difference for the total number of infections.<unk>  uses a fraction of the standard<unk>  of a regular vaccine that is administered by the same, or an alternative route (often subcutaneously or intradermally).<unk>  is used or proposed in a number of relevant infectious poverty diseases including yellow fever, poliomyelitis, COVID-19.
Fractional dose vaccination
Mass vaccination
Pre-exposure prophylaxis
Active immunization
Post-exposure prophylaxis
Pulse vaccination strategy
Alternative vaccination schedule
Genetic vaccine