<unk>  generally responds only to indomethacin 25–300 mg daily, which must be<unk> d long term. Unfortunately, gastrointestinal side effects are a common problem with indomethacin, which may require additional acid-suppression therapy to control. In patients who are unable to tolerate indomethacin, the use of celecoxib 400–800 mg per day (Celebrex) and rofecoxib 50 mg per day (Vioxx - no longer available) have both been shown to be effective and are likely to be associated with fewer GI side effects. There have also been reports of two patients who were successfully managed with topiramate 100–200 mg per day (Topamax) although side effects with this treatment can also prove problematic. Greater occipital nerve (GON) block comprising 40 mg Depomedrone and 10 mls of 1% Lignocaine injected into the affected nerve is effective, up to a period of approximately three months. Changing the 'cocktail' to include (for example) 10 mls of .5% Marcaine and changing to 2% Lignocaine, whilst in theory should increase the longevity, renders the injection completely ineffective. See 4.2 Posology and method of administration (flocculation). Occipital nerve stimulation may be highly effective when other treatments fail to relieve the intractable pain.
Hemicrania continua
Arachnoid cyst
Meningohydroencephalocoele
Periventricular leukomalacia
Hydrocephalus
Subdural hygroma
Intraventricular hemorrhage
Cerebrospinal fluid leak