Synthesis<unk> is chiral at its phosphorus atom. The individual enantiomers are identified as SP-(−)-VX, and RP-(+)-VX (where the "P" subscript highlights that the chirality is at phosphorus).<unk> is produced via the transester process, which gives a racemic mixture of the two enantiomers. This entails a series of steps whereby phosphorus trichloride is methylated to produce methyl phosphonous dichloride. The resulting material is reacted with ethanol to form a diester. This is then transesterified with N,N-diisopropylaminoethanol to produce the mixed phosphonite. Finally, this immediate precursor is reacted with sulfur to form<unk> . center<unk> can also be delivered in binary chemical weapons which mix in-flight to form the agent prior to release. Binary<unk> is referred to as<unk> 2, and is created by mixing O-(2-diisopropylaminoethyl) O′-ethyl methylphosphonite (Agent QL) with elemental sulfur (Agent NE) as is done in the Bigeye aerial chemical bomb. It may also be produced by mixing with sulfur compounds, as with the liquid dimethyl polysulfide mixture (Agent NM) in the canceled XM736 8-inch projectile program. Solvolysis Like other organophosphorus nerve agents,<unk> may be destroyed by reaction with strong nucleophiles. The reaction of<unk> with concentrated aqueous sodium hydroxide results in two competing solvolysis reactions: cleavage of either the P–O or P–S esters. Although the P–S cleavage is the dominant pathway, the product of P–O bond cleavage is the toxic phosphonic thioester EA-2192 and both reactions are slow. In contrast, reaction with the hydroperoxide anion (hydroperoxidolysis) leads to exclusive cleavage of the P–S bond and a more rapid overall reaction. P–S cleavage (non-toxic products) P-O cleavage (EA-2192 product is still toxic)
VX 
VG 
SmeT
Bra
VistA
Sim4
MVA-B
ReNu