Plaque of<unk>  Plaque of<unk>  on foot treated with imiquimod at Penn Medicine in Philadelphia, and then radiation at Lehigh Valley Hospital. The symptoms of<unk>  are categorized into three clinical stages: the patch stage, the plaque stage, and the tumour stage. The patch stage is defined by flat, reddish patches of varying sizes that may have a wrinkled appearance. They can also look yellowish in people with darker skin. The plaque stage follows the patch stage of<unk> . It is characterized by the presence of raised lesions that appear reddish-brown; in darker skin tones, plaques may have a greyish or silver appearance. Both patch and plaque stages are considered early-stage<unk> . The tumour stage typically shows large irregular lumps. Tumours can develop form plaques or normal skin in any region of the body, including the face and head regions. The symptoms displayed are progressive, with early stages consisting of lesions presented as scaly patches. Lesions often initially develop on the trunk of the body in places that are rarely exposed to the sun, such as the buttocks. These lesions can start as insignificant patches and may remain undiagnosed for up to a decade. Hypopigmentation (when the skin is lighter than normal) of lesions are less common but can be found in children, adolescents and/or dark-skinned individuals. The advanced stage of<unk>  is characterized by generalized erythroderma (red rash covering most of the body) with severe pruritus (itching) and scaling. Itching (Pruritus) is the most commonly reported symptom of people experiencing<unk>  with up to 88% of people reporting varying intensities of pruritus that typically worsens as the disease progresses. Those that experience intense pruritus commonly indicate that it negatively affects their quality of life emotionally, functionally and physically.<unk>  <unk>  and sezary syndrome (SS) are related conditions with the same type of cancer t-lymphocytes that initially grow in different body compartments. SS cells are mainly found in the blood, whereas<unk>  typically involves the skin. In advanced stages of<unk> , the cancer cells move from the skin into the blood stream and other organs, and is referred to as "leukemic<unk> ", :Sézary syndrome preceded by<unk> ", or "secondary<unk> ".
Mycosis fungoides
Sycosis vulgaris
Keratoderma climactericum
Tinea versicolor
Lymphomatoid papulosis
Actinic granuloma
Diabetic dermadrome
Granuloma faciale