A tube of<unk> <unk>  is primarily used to treat: bacterial vaginosis, pelvic inflammatory disease (along with other antibacterials like ceftriaxone), pseudomembranous colitis, aspiration pneumonia, rosacea (topical), fungating wounds (topical), intra-abdominal infections, lung abscess, periodontitis, amoebiasis, oral infections, giardiasis, trichomoniasis, and infections caused by susceptible anaerobic organisms such as Bacteroides, Fusobacterium, Clostridium, Peptostreptococcus, and Prevotella species. It is also often used to eradicate Helicobacter pylori along with other drugs and to prevent infection in people recovering from surgery.<unk>  is bitter and so the liquid suspension contains<unk>  benzoate. This may require hydrolysis in the gastrointestinal tract and some sources speculate that it may be unsuitable in people with diarrhea or feeding-tubes in the duodenum or jejunum. Bacterial vaginosis Drugs of choice for the treatment of bacterial vaginosis include<unk>  and clindamycin. The treatment of choice for bacterial vaginosis in nonpregnant women include<unk>  oral twice daily for seven days, or<unk>  gel intravaginally once daily for five days, or clindamycin intravaginally at bedtime for seven days. For pregnant women, the treatment of choice is<unk>  oral three times a day for seven days. Data does not report routine treatment of male sexual partners. Trichomoniasis The 5-nitroimidazole drugs<unk>  and tinidazole) are the mainstay of treatment for infection with Trichomonas vaginalis. Treatment for both the infected patient and the patient's sexual partner is recommended, even if asymptomatic. Therapy other than 5-nitroimidazole drugs is also an option, but cure rates are much lower. Giardiasis Oral<unk>  is a treatment option for giardiasis, however, the increasing incidence of nitroimidazole resistance is leading to the increased use of other compound classes. Dracunculus In the case of Dracunculus medinensis (Guinea worm),<unk>  just eases worm extraction rather than killing the worm. C. difficile colitis Initial antibiotic therapy for less-severe Clostridioides difficile infection colitis (pseudomembranous colitis) consists of<unk> , vancomycin, or fidaxomicin by mouth. In 2017, the IDSA generally recommended vancomycin and fidaxomicin over<unk> . Vancomycin by mouth has been shown to be more effective in treating people with severe C. difficile colitis. E. histolytica Entamoeba histolytica invasive amebiasis is treated with<unk>  for eradication, in combination with diloxanide to prevent recurrence. Although it is generally a standard treatment it is associated with some side effects. Preterm births<unk>  has also been used in women to prevent preterm birth associated with bacterial vaginosis, amongst other risk factors including the presence of cervicovaginal fetal fibronectin (fFN).<unk>  was ineffective in preventing preterm delivery in high-risk pregnant women (selected by history and a positive fFN test) and, conversely, the incidence of preterm delivery was found to be higher in women treated with<unk> . Hypoxic radiosensitizer In addition to its anti-biotic properties, attempts were also made to use a possible radiation-sensitizing effect of<unk>  in the context of radiation therapy against hypoxic tumors. However, the neurotoxic side effects occurring at the required dosages have prevented the widespread use of<unk>  as an adjuvant agent in radiation therapy. However, other nitroimidazoles derived from<unk>  such as nimorazole with reduced electron affinity showed less serious neuronal side effects and have found their way into radio-onological practice for head and neck tumors in some countries. Perioral dermatitis Canadian Family Physician has recommended topical<unk>  as a third-line treatment for the perioral dermatitis either along with or without oral tetracycline or oral erythromycin as first and second line treatment respectively.
Metronidazole
Secnidazole
Fexinidazole
Tinidazole
Benznidazole
Meropenem
Ornidazole
Norfloxacin