The key problem is the early fusion of the skull, which can be corrected by a series of surgical procedures, often within the first three months after birth. Later surgeries are necessary to correct respiratory and facial deformities.
Pfeiffer syndrome
Zechi-Ceide syndrome
Johanson–Blizzard syndrome
Gómez–López-Hernández syndrome
Sanjad-Sakati syndrome
Adams–Nance syndrome
Lucey–Driscoll syndrome
Twiddler's syndrome