<unk>  is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL). It is given by injection into a vein, muscle, or under the skin. A pegylated version is also available. In food manufacturing it is used to decrease acrylamide. Common side effects when used by injection include allergic reactions, pancreatitis, blood clotting problems, high blood sugar, kidney problems, and liver dysfunction. Use in pregnancy may harm the baby. As a food it is generally recognized as safe.<unk>  works by breaking down the amino acid known as<unk> aragine without which the cancer cells cannot make protein. The most common adverse reactions of<unk>  erwinia chrysanthemi (recombinant)-rywn include abnormal liver tests, nausea, musculoskeletal pain, fatigue, infection, headache, pyrexia, drug hypersensitivity, febrile neutropenia, decreased appetite, stomatitis, bleeding, and hyperglycemia.<unk>  was approved for medical use in the United States in 1978. It is on the World Health Organization's List of Essential Medicines. It is often made from Escherichia coli (E. coli) or Erwinia chrysanthemi.
Asparaginase
Xanthine oxidase
Transaminase
Phenylalanine hydroxylase
Thymidine phosphorylase
Galactose-1-phosphate uridylyltransferase
Aldehyde dehydrogenase
Biotinidase