The first symptoms include muscle cramps and muscle twitches affecting the upper and lower limbs. They appear usually after age of 40. The disease is slowly progressive with adult onset and results in weakness and mild muscle atrophy. The disease does not affect life expectancy. However, it is difficult to differentiate the disease from a more fatal amyotrophic lateral sclerosis in diagnosis. Ultimately, SMAJ can lead to reduced ability in motor function for skills such as walking. SMAJ may also reduce one’s nerve function and ability to sense vibrations.
Jokela type spinal muscular atrophy
Fukuyama congenital muscular dystrophy
Madras motor neuron disease
X-linked spinal muscular atrophy type 2
Distal spinal muscular atrophy type 2
Distal spinal muscular atrophy type 1
Ullrich congenital muscular dystrophy
Becker muscular dystrophy