Although all early reported cases occurred in the Philippines,<unk>  has been diagnosed in Japan, US, Canada, and Germany in people of Filipino descent. The prevalence in the Philippines has been estimated at 1/322,000 and as high as 1/4,000 in the province of Capiz's male population. As an<unk><unk>  recessive disease, the majority of those affected are males with females generally being asymptomatic carriers. In the largest described series, the mean age of onset was 39.7 years, the mean duration of illness was 16 years, and the mean age of death was 55.6 years.
X-linked dystonia parkinsonism
Huntington's disease-like syndrome
Madras motor neuron disease
Fragile X-associated tremor/ataxia syndrome
Parkinson-plus syndrome
Benign hereditary chorea
Stratton Parker syndrome
Babinski–Nageotte syndrome