Cervical vertebrae DIRA displays a constellation of serious symptoms which include respiratory distress, as well as the following:
Deficiency of the interleukin-1–receptor antagonist
Leukocyte adhesion molecule deficiency
Terminal complement pathway deficiency
Neutrophil-specific granule deficiency
Acquired C1 esterase inhibitor deficiency
Mendelian susceptibility to mycobacterial disease
CD25 deficiency
Immunodeficiency with hyperimmunoglobulin M