The diagnosis is based on a clinical presentation, molecular analysis, electropherogram and radiograph. This disease is diagnosed within the first few years of life. Identification of the main characteristics is the key factor in diagnosis. Molecular analysis is used to examine the DNA of the affected person and their parents. For this, a blood sample is needed and the DNA will be extracted with an automatic DNA extractor. The results will show the mutated chromosome and identify if this chromosome was passed on from a parent. A radiograph will show abnormal growth plates and misshapen bones in the limbs. This can confirm the abnormal development and premature fusion of the regions where the diaphyses, of certain long bones, meet their epiphyses. Electropherogram is used to identify genotyping. These results can be used to compare to a normal sequence and relatives sequences. This is a radiograph of the left hand that shows the different types of joints. This scan can show the growth plate and the shape of each bone. It is important to have a detailed patient history, including the parents or other relatives. Typically, the parent that carries the chromosome for AMD, seems to be shorter than average. Monitoring the weight and height of the person affected with AMD is important. Based on the person's age, they should be meeting a certain percentile to identify any issues that may be causing a stunt in growth. There are five types of AMD: # Osebold-Remondini # Maroteaux # Grebe dysplasia # Du Pan syndrome #<unk>  with genital anomalies Osebold-Remondini causes shortness of limbs and hypoplasia of the second phalanges with fusion to the remaining phalanges, carpal and tarsal coalitions. Maroteaux type causes severe dwarfism with a height below 120 cm. This type also causes shortening of the middle and distal segments of the limbs. Grebe dysplasia causes extreme abnormalities of the limb joints and limbs. In this type of AMD, the hands and feet are affected the most. This type primarily affects the joints in the hands and feet causing a lack of articulation. Grebe dysplasia does not have any major effects on the stature. Du Pan syndrome causes underdevelopment of the tissues in the fibulae, feet and hands.<unk>  with genital anomalies causes shortness of limbs and stature with congenital malformations of the female genital tract and male reproductive system. All five types of AMD are caused by a gene mutation or receiving it from their parents. The differences between the types are the different genes that are affected. The mutated gene for each type is listed in the pathophysiology section.
Acromesomelic dysplasia
Campomelic dysplasia
Hereditary coproporphyria
Langer mesomelic dysplasia
Rhizomelic chondrodysplasia punctata
Mondini dysplasia
Brill–Zinsser disease
Degos disease