The main clinical features are signature language<unk>  difficulties with speech production. There can be problems in different parts of the speech production system, hence patients can present with articulatory breakdown, phonemic breakdown (difficulties with sounds) and other problems. However, it is rare for patients to have just one of these problems and most people will present with more than one problem. Features include: * Hesitant, effortful speech * Apraxia of speech * Stutter (including return of a childhood stutter) * Anomia * Phonemic paraphasia (sound errors in speech e.g. 'gat' for 'cat') * Agrammatism (using the wrong tense or word order) As the disease develops, speech quantity decreases and many patients become mute. Cognitive domains other than language are rarely affected early on. However, as the disease progresses, other domains can be affected. Problems with writing, reading, and speech comprehension can occur, as can behavioural features similar to frontotemporal dementia.
Progressive nonfluent aphasia
Global aphasia
Anomic aphasia
Expressive aphasia
Receptive aphasia
Social-emotional agnosia
Visuospatial dysgnosia
Hemispatial neglect