Like many chemotherapy drugs,<unk>  may have numerous serious side effects, because it interferes with normal cell growth as well as cancer cell growth. Among the most serious possible side effects are birth defects to children conceived or carried during treatment; sterility, possibly permanent; or immune suppression (reduced ability to fight infection or disease).<unk>  is considered to be highly emetogenic, and most patients will be pre-medicated with dexamethasone and antiemetic drugs like 5-HT3 antagonist (e.g., ondansetron) and/or NK1 receptor antagonist (e.g., aprepitant). Other significant side effects include headache, fatigue and occasionally diarrhea. The Swedish National Board of Health and Welfare has sent out a black box warning and suggests avoiding<unk>  due to liver problems.
Dacarbazine
Hydroxycarbamide
Ifosfamide
Busulfan
Procarbazine
Etoposide
Melphalan
Vincristine