Potential side effects of<unk> s mild – usually goes away potentially serious * Diarrhea * Headache * Insomnia * Nausea * Vomiting * Abdominal pain * Lack of appetite * Yellowed skin * Dizziness * Slow heartbeat * Sudden or substantial weight loss * Weakness Some major effects of cholinesterase inhibitors: * Actions on the parasympathetic nervous system, (the parasympathetic branch of the autonomic nervous system) may cause bradycardia, hypotension, hypersecretion, bronchoconstriction, GI tract hypermotility, and decrease intraocular pressure, increase lower esophageal sphincter (LES) tone * Cholinergic crisis. * Actions on the neuromuscular junction may result in prolonged muscle contraction. *The effects of neostigmine on postoperative nausea and vomiting are controversial and there is not a clear linkage in clinical practice, however, there is good evidence to support the reduction in risk when anticholinergic agents are administered. Administration of reversible cholinoesterase inhibitors is contraindicated with those that have urinary retention due to urethral obstruction. Overdose *Hyperstimulation of nicotinic and muscarinic receptors.
Acetylcholinesterase inhibitor
Cholinesterase inhibitor
Monoamine oxidase inhibitor
GABA analogue
GABA reuptake inhibitor
Glycine reuptake inhibitor
Adenosine reuptake inhibitor
Opioid antagonist