Typically, diagnosis involves several preliminary tests of immune function, including basic evaluation of the humoral immune system and the cell-mediated immune system. A WBC differential will reveal extremely elevated levels of neutrophils (on the order of 6-10x normal) because they are unable to leave the blood vessels. In the case of<unk> -I, specific diagnosis is done by flow cytometry. This technique will reveal absent or reduced CD18 expression in the leukocyte membrane. Recently, prenatal diagnosis systems has been established, allowing an early detection of the disease.<unk> -II diagnosis includes the study of different glycosylated forms of the transferrin protein. In<unk> -III, as platelet function is also affected, this could be used to differentiate it from the other types.
Leukocyte adhesion deficiency
Leukocyte adhesion molecule deficiency
Myeloperoxidase deficiency
Primary immunodeficiency
Neutrophil-specific granule deficiency
MBL deficiency
Combined immunodeficiencies
IgG deficiency