<unk>  is also an inhibitor of the cytochrome P450 enzyme 2D6, and can lead to increased blood levels of lidocaine, beta blockers, opioids, and some antidepressants.<unk>  also inhibits the transport protein P-glycoprotein and so can cause some peripherally acting drugs such as loperamide to have central nervous system side effects, such as respiratory depression, if the two drugs are coadministered.<unk>  can cause thrombocytopenia, granulomatous hepatitis, myasthenia gravis, and torsades de pointes (dangerous heart rhythm), so is not used much today. Torsades can occur after the first dose.<unk> -induced thrombocytopenia (low platelet count) is mediated by the immune system, and may lead to thrombocytic purpura.<unk>  intoxication can lead to a collection of symptoms collectively known as cinchonism, with tinnitus (ringing in the ears) being among the most characteristic and common symptoms of this toxicity syndrome.
Quinidine
Lidocaine
Nortilidine
Colestilan
Ibutilide
Maprotiline
Etidocaine
Amiodarone