These drug interactions with<unk>  are considered major and may need therapy modifications: *Bile acid sequestrants (e.g. cholestyramine, colestipol, etc.): If taken together, bile acid resins may bind to<unk> , resulting in a decrease in<unk>  absorption. To maximize absorption, patients need to separate administration by at least 1 h before or 4 h to 6 h after taking the bile acid sequestrant. *Immunosuppressants (e.g. ciclosporin or tacrolimus): An increased risk of renal dysfunction exists with concomitant use of immunosuppressants and<unk> . Approach with caution when coadministering additional medications that decrease renal function. *Vitamin K antagonists (e.g. warfarin): As previously mentioned,<unk>  interacts with coumadin anticoagulants to increase the risk of bleeding. Dosage adjustment of vitamin K antagonist may be necessary. *Statins: Combination of statins and<unk>  may increase the risk of rhabdomyolysis or myopathy.
Fenofibrate
Clofibrate
Ezetimibe
Lovastatin
Atorvastatin
Simvastatin
Gemfibrozil
Fluvastatin