Due to an insufficient capacity of subcutaneous adipose tissue to store fat, fat is deposited in non-adipose tissue <unk> toxicity), leading to insulin resistance. Patients display hypertriglyceridemia, severe fatty liver disease and little or no adipose tissue. Average patient lifespan is approximately 30 years before death, with liver failure being the usual cause of death. In contrast to the high levels seen in non-alcoholic fatty liver disease associated with obesity, leptin levels are very low in<unk> .
Lipodystrophy
Lymphedema
Osteodystrophy
Scarring hair loss
Acanthosis nigricans
Presbyphagia
Pseudodysphagia
Trichomegaly