<unk> s work the same way that viral vaccines work, by training the immune system to attack cells that contain the<unk> s in the vaccine. The difference is that the<unk> s for viral vaccines are derived from viruses or cells infected with virus, while the<unk> s for<unk> s are derived from cancer cells. Since<unk><unk> s are<unk> s found in cancer cells but not normal cells, vaccinations containing<unk><unk> s should train the immune system to target cancer cells not healthy cells. Cancer-specific<unk><unk> s include peptides from proteins that are not typically found in normal cells but are activated in cancer cells or peptides containing cancer-specific mutations.<unk> -presenting cells (APCs) such as dendritic cells take up<unk> s from the vaccine, process them into epitopes, and present the epitopes to T-cells via Major Histocompatibility Complex proteins. If T-cells recognize the epitope as foreign, the adaptive immune system is activated and target cells that express the<unk> s.
Tumor antigen vaccine
Dendritic cell-based cancer vaccine
Cancer vaccine
Antigen-presenting cell vaccine
Therapeutic vaccines
T-cell vaccination
Cancer immunotherapy
Vaccine therapy