Figure comparing the effects of exposure to genotoxic agents (aneugens and<unk> s) on DNA. Aneugens induce mis-segregation of chromosomes into daughter cells while<unk> s break the DNA and chromosome. A<unk>  is a mutagenic agent that disturbs normal DNA related processes or directly causes DNA strand breakages, thus causing the deletion, insertion, or rearrangement of entire chromosome sections. These processes are a form of mutagenesis which if left unrepaired, or improperly repaired, can lead to cancer. Known<unk> s include acridine yellow, benzene, ethylene oxide, arsenic, phosphine, mimosine, actinomycin D, camptothecin, methotrexate, methyl acrylate, resorcinol and 5-fluorodeoxyuridine. Additionally, 1,2-dimethylhydrazine is a known colon carcinogen and shows signs of possessing<unk> ic activity. There are many<unk> s not listed here and research is ongoing to discover new<unk> s. Some known<unk> s only exhibit<unk> ic activity in certain cell types, such as caffeine which exhibits<unk> ic activity in plant cells. Researchers are interested in<unk> s for researching cancer, as well as for other human health concerns such as the inheritability of<unk>  effected paternal germ cells that lead to fetus developmental defects.
Clastogen
Immunoevasin
Endrin
Tetanospasmin
Anordrin
Dieldrin
Prohormone
Serpin