Common signs of<unk>  are trigonocephaly as well as head and neck symptoms. The head and neck symptoms come in the form of craniosynostosis affecting the metopic suture (the dense connective tissue structure that divides the two halves of the skull in children which usually fuse together by the age of six). Symptoms of<unk>  other than developmental delay and short stature include * Intellectual disability. * Low-set ears/posteriorly rotated ears * Intellectual deficit as well as learning disability * Intrauterine growth retardation (poor growth of a baby while it is in the mother's womb) * Posterior fontanel * Premature synostosis of the lambdoid suture (the fusion of the bones to the joint is premature) * Narrow forehead * Trigonocephaly (a frontal bone anomaly that is characterized by a premature fusion of the bones which gives the forehead a triangular shape) * Hypotelorism or hypertelorism (reduced or increased width between the eyes) * Craniosynostosis (when one or more seam-like junctions between two bones fuses by turning into bone. This changes the growth pattern of the skull) * Low birth weight and height The affected patients sometimes show a highly arched palate, clinodactyly (a defect in which toes or fingers are positioned abnormally) and ventricular septal defect (a heart defect that allows blood to pass directly from left to the right ventricle which is caused by an opening in the septum). Overall,<unk>  impairs growth, motor function, and mental state. Growth and development The growth retardation dates from the intrauterine period (development in the uterus.) The long-term developmental growth and outcome is not known, but the early childhood development is known, which is said to be moderately delayed. Craniosynostosis is usually rare among the X-Linked Intellectual Disability Syndromes, but when it is present, it affects the metopic structure (forehead).
Say–Meyer syndrome
Madras motor neuron disease
Nicolau–Balus syndrome
Dejerine–Sottas disease
Parkes Weber syndrome
Spinal muscular atrophy
Urban–Rogers–Meyer syndrome
Babinski–Nageotte syndrome