Multiplex RNA visualization in cells using ViewRNA<unk>  Assays A metaphase cell positive for the bcr/abl rearrangement (associated with chronic myelogenous leukemia) using<unk> . The chromosomes can be seen in blue. The chromosome that is labeled with green and red spots (upper left) is the one where the rearrangement is present.<unk>  <unk>  is a molecular cytogenetic technique that uses fluorescent probes that bind to only particular parts of a nucleic acid sequence with a high degree of sequence complementarity. It was developed by biomedical researchers in the early 1980s to detect and localize the presence or absence of specific DNA sequences on chromosomes.<unk>  microscopy can be used to find out where the fluorescent probe is bound to the chromosomes.<unk>  is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification.<unk>  can also be used to detect and localize specific RNA targets (mRNA, lncRNA and miRNA) in cells, circulating tumor cells, and tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues.
Fluorescence in situ hybridization
DNA profiling
Immunohistochemistry
Immunostaining
Chromatin immunoprecipitation
Methylation specific oligonucleotide microarray
Polymerase chain reaction
Immunolabeling