The exact mechanism is unknown, however there appears to be a component of abnormal corneal endothelium that proliferates onto the iris forming a membrane that then obstructs the trabecular meshwork, leading to iris distortion. Nodule formation can also occur when the abnormal corneal endothelium causes contractions around the iris stroma. Herpesvirus DNA has been identified in some patients following keratoplasty, suggesting the possibility that herpes simplex virus may induce the abnormal<unk> ation in the anterior chamber angle and on the surface of the iris. Variations The Chandler variant of ICE is characterized by pathology on the inner surface of the cornea leading to abnormal<unk>  pump function. Other features include possible mild iris changes, corneal edema, and normal to slight elevations in intraocular pressure. Cogan-Reese variant is characterized by multiple pigmented iris nodules. This variant is most commonly unilateral and seen in middle-aged females.
Iridocorneal endothelial syndrome
Fuchs heterochromic iridocyclitis
Phacolytic glaucoma
Ocular ischemic syndrome
Neurotrophic keratitis
Sympathetic ophthalmia
Ghost cell glaucoma
Lattice corneal dystrophy