<unk> , also referred to as light-chain<unk>  nephropathy, is the formation of plugs (urinary<unk> s) in the kidney tubules from free immunoglobulin light chains leading to kidney failure in the context of multiple<unk> . It is the most common cause of kidney injury in<unk> . In<unk> , filtered κ or λ light chains that bind to Tamm-Horsfall protein precipitate in the kidney's tubules. Hypercalcemia and low fluid intake contribute to the development of<unk> s.<unk>  is considered to be a medical emergency because if untreated, it leads to irreversible kidney failure. It is diagnosed by histological examination of kidney biopsy.
Myeloma cast nephropathy
Analgesic nephropathy
IgA nephropathy
Shunt nephritis
Focal proliferative nephritis
Sickle cell nephropathy
Diffuse proliferative nephritis
Membranous glomerulonephritis