<unk>  is a difficult term because it can be used to denote either a disease or finding (i.e., an observable sign in a person). When referring to a finding,<unk>  refers to permanent (or degenerative) brain injury, or a reversible one. It can be due to direct injury to the brain, or illness remote from the brain. The individual findings that cause a clinician to refer to a person as having<unk>  include intellectual disability, irritability, agitation, delirium, confusion, somnolence, stupor, coma and psychosis. As such, describing a person as having a clinical picture of<unk>  is not a very specific description. When referring to a disease,<unk>  refers to a wide variety of brain disorders with very different etiologies, prognoses and implications. For example, prion diseases, all of which cause transmissible spongiform<unk> es, are invariably fatal, but other<unk> es are reversible and can have a number of causes including nutritional deficiencies and toxins.
Encephalopathy
Myelopathy
Myopathy
Organomegaly
Neurotoxicity
Cerebral atrophy
Tooth loss
Osteopenia