The U.S. and Canadian Dietary Reference Intake review for protein mentions "rabbit starvation", but concluded that there was not sufficient evidence by 2005 to establish a Tolerable upper intake level, i.e., an upper limit for how much protein can be safely consumed. According to Bilsborough and Mann (2006), protein intake is mainly restricted by the urea cycle, but deriving more than 35% of energy needs from protein leads to health problems. They suggested an upper limit of 25% or 2.5 g/kg, but stated that humans can theoretically use much larger amounts than this for energy. For arctic hunter-gatherers, the amount can seasonally increase to 45%. Protein intakes above 35% of energy needs have also been shown to decrease testosterone and increase cortisol levels. This is thought to be part of the body's attempt to upregulate the urea cycle, and increase nitrogen excretion.
Protein poisoning
Salt poisoning
Tin poisoning
Sulfuric acid poisoning
Protein toxicity
Lead poisoning
Salicylate poisoning
Scombroid food poisoning