In 2009,<unk> <unk>  G was used in scientific experiments to treat spinal injuries in laboratory rats. It acts by reducing the body's natural swelling response, which can cause neurons in the area to die of metabolic stress. Testing on the rats proved effective. In comparison to the rats that had not received the dye, the rats that were treated with the dye performed better on motion tests. It is unknown whether this treatment can be used effectively in humans. The animal experiments administered the dye within 15 minutes of injury, but to be effective in a real-life setting, where it may take time for a patient to reach the emergency room, the treatment needs to be effective even when administered up to two hours after injury. The only reported side effect was that the rats temporarily turned<unk> . Under the trade names ILM<unk>  and<unk>  Peel,<unk> <unk>  G is used as a stain to assist surgeons in retinal surgery. In December 2019,<unk> <unk>  G (under the trade name TissueBlue, DORC International, Netherlands) was approved for use in humans in the United States.
Coomassie brilliant blue
Azo dye
Lactophenol cotton blue
Metacresol purple
Hemichrome
Prussian blue 
Cresyl violet
Infracyanine green