<unk>  is the spasmodic lowering of the upper eyelid on downward rotation of the eye, indicating exophthalmic goiter. Similar to von Graefe's sign, it is observed in people with Graves-Basedow disease, a type of hyperthyroidism. In this disease, the immune system attacks the thyroid gland and the soft tissues surrounding the eyes. As a result, the eyes are often pushed forward in the eye sockets, a condition known as exophthalmos.
Boston's sign
Battle's sign
Ballance's sign
Cullen's sign
Hoover's sign 
Rovsing's sign
Dance's sign
Gowers's sign