<unk>  may occur as an asymptomatic infection, an acute infection (i.e., duration shorter than 2 weeks), as recurrent acute infections in which symptoms reappear following a brief period of recovery for up to 30 days, and as a chronic infection (i.e., duration longer than 2 weeks) in which symptoms are severe and persistent. It may be fatal in individuals with a severely compromised immune system. Symptoms usually appear 5–10 days after infection (range: 2–28 days) and normally last for up to 2 weeks in immunocompetent individuals; symptoms are usually more severe and persist longer in immunocompromised individuals. Following the resolution of diarrhea, symptoms can reoccur after several days or weeks due to reinfection. The likelihood of is high in immunocompromised adults, and low in those with normal immune systems. In immunocompetent individuals,<unk>  is primarily localized to the distal small intestine and sometimes the respiratory tract as well. In immunocompromised persons,<unk>  may disseminate to other organs, including the hepatobiliary system, pancreas, upper gastrointestinal tract, and urinary bladder; pancreatic and biliary infection can involve acalculous cholecystitis, sclerosing cholangitis, papillary stenosis, or pancreatitis. Intestinal<unk>  Common signs and symptoms of intestinal<unk>  include: * Moderate to severe watery diarrhea, sometimes contains mucus and rarely contains blood or leukocytes * In very severe cases, diarrhea may be profuse and cholera-like with malabsorption and hypovolemia * Low-grade fever * Crampy abdominal pain * Dehydration * Weight loss * Fatigue * Nausea and vomiting – suggests upper GI tract involvement and may lead to respiratory<unk>  * Epigastric or right upper quadrant tenderness Less common or rare signs and symptoms include: * Reactive arthritis (may affect the hands, knees, ankles, and feet) * Jaundice – suggests hepatobiliary involvement * Ascites – suggests pancreatic involvement Respiratory<unk>  Symptoms of upper respiratory<unk>  include: * Inflammation of the nasal mucosa, sinuses, larynx, or trachea * Nasal discharge * Voice change (e.g., hoarseness) Symptoms of lower respiratory<unk>  include: * Cough * Shortness of breath * Fever * Hypoxemia
Cryptosporidiosis
Rhinosporidiosis
Cyclosporiasis
Porcine intestinal spirochaetosis
Isosporiasis
Rotaviral gastroenteritis
Bartonellosis
Travelers' diarrhea