<unk>  is a common condition, defined by a difference of 0.4 mm or more between the sizes of the pupils of the eyes.<unk>  has various causes: * Physiological<unk> : About 20% of population has a slight difference in pupil size which is known as physiological<unk> . In this condition, the difference between pupils is usually less than 1 mm. * Horner's syndrome * Mechanical<unk> : Occasionally previous trauma, eye surgery, or inflammation (uveitis, angle closure glaucoma) can lead to adhesions between the iris and the lens. * Adie tonic pupil: Tonic pupil is usually an isolated benign entity, presenting in young women. It may be associated with loss of deep tendon reflex (Adie's syndrome). Tonic pupil is characterized by delayed dilation of iris especially after near stimulus, segmental iris constriction, and sensitivity of pupil to a weak solution of pilocarpine. * Oculomotor nerve palsy: Ischemia, intracranial aneurysm, demyelinating diseases (e.g., multiple sclerosis), head trauma, and brain tumors are the most common causes of oculomotor nerve palsy in adults. In ischemic lesions of the oculomotor nerve, pupillary function is usually spared whereas in compressive lesions the pupil is involved. * Pharmacological agents with anticholinergic or sympathomimetic properties will cause<unk> , particularly if instilled in one eye. Some examples of pharmacological agents which may affect the pupils include pilocarpine, cocaine, tropicamide, MDMA, dextromethorphan, and ergolines. Alkaloids present in plants of the genera Brugmansia and Datura, such as scopolamine, may also induce<unk> . *Migraines
Anisocoria
Sclerocornea
Megalocornea
Leukocoria
Periorbital hyperpigmentation
Mechanical anisocoria
Papilledema
Macropsia