Peripheral edema and hypoalbuminemia<unk>  is a form of protein deficiency, which can result in both osmotic imbalances and irregularities in the lymphatic system.<unk>  is most notable for peripheral edema. The presence of edema in<unk>  is correlated with very low albumin concentration (hypoalbuminemia). Edema results from a loss of fluid balance between the hydrostatic and oncotic pressures across the capillary blood vessel walls due to the lack of protein which affects the body's ability to draw fluid from the tissues into the bloodstream. Low albumin concentration influences negatively the strength of oncotic pressure. Failure leads to the fluid buildup in the abdomen, resulting in edema and belly distension. Furthermore, the release of antidiuretic hormone is stimulated by hypovolemia, also leading to the development of peripheral edema. Plasma renin is also stimulated, promoting sodium retention. It is important to distinguish the pathophysiology of marasmus and<unk>  when it comes to treating malnourished children who may have hypovolemic shock that is cause by an acute loss of salt and water. Children with severe albumin deficiency struggle physiologically to maintain their blood volume. Low glutathione levels<unk>  is also marked by low glutathione levels. Glutathione is used in many of the body processes on a molecule level. It is believed to be related to high oxidant levels commonly seen in people who suffer from starvation and rarely in chronic inflammation. Glutathione serves vital functions including management of oxidative stress which is an imbalance that plays a key role in the pathogenesis of many diseases. Cysteine is an essential amino acid that acts as the limiting amino acid for glutathione synthesis in humans. Factors that stimulate cysteine uptake by cells will increase glutathione levels and prevent glutathione deficiency in humans under various conditions including protein malnutrition. Evidence indicates that dietary amino acids balance has an important effect on protein nutrition and therefore on glutathione homeostasis. Others A proposed experimental theory suggests that alterations in the microbiome/virone contributes to edematous malnutrition, but further studies are required to understand the mechanism.
Kwashiorkor
Pellagra
Albinism
Pediatric end-stage liver disease
Philadelphia basement kidnapping
Uddanam nephropathy
Cystic kidney disease
Type 3c diabetes