It is primarily used in the treatment of urinary tract infections, although it may be used against any susceptible aerobic bacterial species. It may also be used to treat and prevent Pneumocystis jirovecii pneumonia. It is generally not recommended for the treatment of anaerobic infections such as Clostridium difficile colitis (the leading cause of antibiotic-induced diarrhea).<unk>  has been used in trials to treat retinitis. Resistance to<unk>  is increasing, but it is still a first line antibiotic in many countries. Spectrum of susceptibility Cultures and susceptibility tests should be done to make sure bacteria are treated by<unk> . * Escherichia coli * Proteus mirabilis * Klebsiella pneumoniae * Enterobacter species * Coagulase-negative Staphylococcus species, including S. saprophyticus * Streptococcus pneumoniae * Haemophilus influenzae
Trimethoprim
Sulfamethoxazole
Moxifloxacin
Enrofloxacin
Phenoxymethylpenicillin
Doxycycline
Tetracycline
Minocycline