<unk> es are conditions which cause impairment of<unk> <unk> ty, which can lead to<unk><unk> . It can be mediated by insufficient number or function of B cells, the plasma cells they differentiate into, or the antibody secreted by the plasma cells. The most common such<unk><unk>  is inherited selective IgA<unk> , occurring between 1 in 100 and 1 in 1000 persons, depending on population. They are associated with increased vulnerability to infection, but can be difficult to detect (or asymptomatic) in the absence of infection.
Humoral immune deficiency
T cell deficiency
IgG deficiency
Inborn errors of immunity
Neutrophil-specific granule deficiency
Inherited disorders of trafficking
Surfactant metabolism dysfunction
Mendelian susceptibility to mycobacterial disease