<unk>  in a patient with cold agglutinin disease. In hematology,<unk>  or autoagglutination is a phenomenon in which<unk>  blood<unk> s clump together, forming aggregates. It is caused by the surface of the<unk> <unk> s being coated with antibodies. This often occurs in cold agglutinin disease, a type of autoimmune hemolytic anemia in which people produce antibodies (termed cold agglutinins) that bind to their<unk>  blood<unk> s at cold temperatures and destroy them. People may develop cold agglutinins from lymphoproliferative disorders, from infection with Mycoplasma pneumoniae or Epstein-Barr virus, or idiopathically (without any apparent cause).<unk>  can also occur in paroxysmal nocturnal hemoglobinuria and warm autoimmune hemolytic anemia. In cases of<unk> , the direct antiglobulin test can be used to demonstrate the presence of antibodies bound to the<unk> <unk> s. __TOC__
Red cell agglutination
Cytotoxicity
Thrombocythemia
Leukostasis
Erythrocyte fragility
Myocytolysis
Thrombocytopenia
Leukocytosis