The incidence of<unk>  is estimated to occur in 1 in 40,000 to 1 in 160,000 individuals worldwide. There is a much higher incidence in certain genetically isolated populations, such as 1 in 75 in Habbanites (a small group of Jews who immigrated to Israel from southern Arabia), 1 in 2,500 in the western portion of the Navajo Nation, and 1 in 8,000 among Arab groups in Israel. As an autosomal recessive disease, 1 in 40,000 equates to a 1 in 100 carrier frequency in the general population. There are an estimated 3,600<unk>  births per year, with 1,900 alive in the US, 3,100 in Europe, and 49,000 alive worldwide with<unk> .<unk>  is considered a rare disease in the US and other countries.
Metachromatic leukodystrophy
Multiple system atrophy
Leukodystrophy
Benign hereditary chorea
Stratton Parker syndrome
Spinocerebellar ataxia type 6
Infantile neuroaxonal dystrophy
Progressive supranuclear palsy