<unk> cells are a model cell line used in biomedical research. They were isolated from the histiocytic lymphoma of a 37-year-old male patient and are used to study the behaviour and differentiation of monocytes.<unk> cells mature and differentiate in response to a number of soluble stimuli, adopting the morphology and characteristics of mature macrophages.<unk> cells are of the myeloid lineage and so secrete a large number of cytokines and chemokines either constitutively (e.g. IL-1 and GM-CSF) or in response to soluble stimuli. TNFα and recombinant GM-CSF independently promote IL-10 production in<unk> cells. The HLA alleles present in<unk> cells are HLA-A*03:01, A*31:01, B*18:01, B*51:01, Cw*01:02 and Cw*07:02.
U937 
Muse cell
G cell
Basophil
Lymphoblast
Prolymphocyte
HT1080
Mast cell