<unk>  is an autosomal recessive metabolic disorder in which biotin is not released from proteins in the diet during digestion or from normal protein turnover in the cell. This situation results in biotin<unk> . Biotin is an important water-soluble nutrient that aids in the metabolism of fats, carbohydrates, and proteins. Biotin<unk>  can result in behavioral disorders, lack of coordination, learning disabilities and seizures. Biotin supplementation can alleviate and sometimes totally stop such symptoms.
Biotinidase deficiency
D-bifunctional protein deficiency
Glutaminase deficiency
Aromatic L-amino acid decarboxylase deficiency
Ornithine aminotransferase deficiency
Enolase deficiency
Arginine:glycine amidinotransferase deficiency
Holocarboxylase synthetase deficiency