<unk>  tablets<unk>  is a first-generation antihistamine used to treat a number of conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms.<unk>  also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as lidocaine. Allergies<unk>  is effective in treatment of allergies. , it was the most commonly used antihistamine for acute allergic reactions in the emergency department. By injection it is often used in addition to epinephrine for anaphylaxis, although its use for this purpose had not been properly studied. Its use is only recommended once acute symptoms have improved. A bottle of topical "Itch-Stopping Gel"<unk>  Topical formulations of<unk>  are available, including creams, lotions, gels, and sprays. These are used to relieve itching and have the advantage of causing fewer systemic effects (e.g., drowsiness) than oral forms. Movement disorders<unk>  is used to treat akathisia and Parkinson's disease–like extrapyramidal symptoms caused by antipsychotics. It is also used to treat acute dystonia including torticollis and oculogyric crisis caused by first generation antipsychotics. Sleep Because of its sedative properties,<unk>  is widely used in nonprescription sleep aids for insomnia. The drug is an ingredient in several products sold as sleep aids, either alone or in combination with other ingredients such as acetaminophen (paracetamol) in Tylenol PM or ibuprofen in Advil PM.<unk>  can cause minor psychological dependence.<unk>  has also been used as an anxiolytic.<unk>  has also been used off prescription by parents in an attempt to make their children sleep or remain sedated on long-distance flights. This has been met with criticism, both by doctors and members of the airline industry, as sedating young passengers may put them at risk if the flight encounters an emergency and they are unable to react to the situation efficiently, and the drug's side effects, especially the chance of a paradoxical reaction, may result in some individuals becoming hyperactive rather than sedated. The ethics of this use have also been challenged, with the Seattle Children's hospital arguing in a 2009 article that 'Using a medication for your convenience is never an indication for medication in a child.' The American Academy of Sleep Medicine's 2017 clinical practice guidelines recommended against the use of<unk>  in the treatment of insomnia due to poor effectiveness and low quality of evidence. Doses of<unk>  that have been used for sleep range from 12.5 to 100 mg, with a typical dose of 50 mg. Nausea<unk>  also has antiemetic properties, which make it useful in treating the nausea that occurs in vertigo and motion sickness. Special populations<unk>  is not recommended for people older than 60 or children under the age of six, unless a physician is consulted. These populations should be treated with second-generation antihistamines such as loratadine, desloratadine, fexofenadine, cetirizine, levocetirizine, and azelastine. Due to its strong anticholinergic effects,<unk>  is on the Beers list of drugs to avoid in the elderly.<unk>  is category B in the FDA Classification of Drug Safety During Pregnancy. It is also excreted in breast milk. It is expected that low doses of<unk>  taken occasionally will not cause any adverse effects on breastfed infants. Large doses or long-term use may affect the baby or reduce breast milk supply, especially when combined with sympathomimetic drugs such as pseudoephedrine or before the establishment of lactation. A single bedtime dose after the last feeding of the day may minimize any harmful effects of the medication on the baby and on the milk supply. Still, non-sedating antihistamines are the preferred alternative. Paradoxical reactions to<unk>  have been documented, in particular among children, and it may cause excitation instead of sedation. Topical<unk>  is sometimes used especially for people in hospice. This use is without indication and topical<unk>  should not be used as treatment for nausea because research does not indicate this therapy is more effective than alternatives. There were no documented cases of clinically apparent acute liver injury caused by normal doses of<unk> .
Diphenhydramine
Olopatadine
Ephedrine
Pseudoephedrine
Meclizine
Lofepramine
Dezocine
Molsidomine