In in vivo systems it is often used to quantify the binding of a test molecule to the binding site of radioligand. The higher the affinity of the molecule the more radioligand is displaced from the binding site and the increasing radioactive decay can be measured by scintillography. This assay is commonly used to calculate binding constant of molecules to receptors. Due to the probable injuries of<unk> s, they could not be administrated in the normal doses of the medications. Therefore, the binding affinity (PKD) of the<unk> -tracers must be high. In addition, since via the<unk>  imaging technique is desired to investigate a function accurately, the selectivity of bindings to the specific targets is very important.
PET radiotracer
Imaging biomarker
Nuclear medicine
Radiomics
Radioactive tracer
Molecular imaging
Tumor marker
Radiochemistry