<unk>  is an odorless, white, crystalline powder, soluble in water and sparingly soluble in methanol. Stereochemistry<unk>  contains a stereocenter and consists of two enantiomers, making it a racemate; i.e., a 1:1 mixture of (R)- and (S)-forms: Enantiomers of<unk>  250 px(R)-midodrine CAS number: 133163-25-4 250 px(S)-midodrine CAS number: 133267-39-7 Synthesis Acylation of 1,4-dimethoxybenzene with chloroacetyl chloride gives the chloroketone 2. The halogen is then converted to the amine 3 by any set of standard schemes, and the ketone reduced to an alcohol with borohydride (4). Acylation of the amino group in this last intermediate with chloroacetyl chloride affords the amide 5. The halogen is then displaced with azide and the resulting product 6 reduced catalytically to the glycinamide,<unk>  (7). Synthesis of<unk>  See also:
Midodrine
Ritodrine
Minaprine
Erythrocrine
Amixetrine
Testosterone ketolaurate
Carbetocin
Halofantrine