<unk>  (LFS) is an X-linked genetic disorder that causes mild to moderate intellectual disability and features described as Marfanoid habitus, referring to a group of physical characteristics similar to those found in Marfan<unk> . These features include a tall, thin stature and long, slender limbs. LFS is also associated with psychopathology and behavioral abnormalities, and it exhibits a number of malformations affecting the brain and heart. The disorder is inherited in an X-linked dominant manner, and is attributed to a missense mutation in the MED12 gene. There is currently no treatment or therapy for the underlying MED12 malfunction, and the exact cause of the disorder remains unclear.
Lujan–Fryns syndrome
McKittrick-Wheelock syndrome
Smith–Fineman–Myers syndrome
Fox–Fordyce disease
McGillivray syndrome
Townes–Brocks syndrome
Kearns–Sayre syndrome
Flynn–Aird syndrome