<unk>  is used to treat certain multidrug-resistant gram-negative infections.<unk>  is used for the treatment of: * complicated intra-abdominal infections. In these cases it is often used in combination with metronidazole, which provides coverage for anaerobic pathogens. * complicated urinary tract infections, including acute pyelonephritis, in adults. * hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. Bacterial activity For many bacterial infections, it offers little or no advantage over<unk>  monotherapy, due to the widespread expression of resistance mechanisms other than β-lactamase production. These include Haemophilus, Moraxella and Neisseria pathogens, and infections caused by Acinectobacter baumannii. The antibacterial spectrum of<unk>  includes nearly all Enterobacteriaceae, including<unk> -resistant strains. The activity of<unk>  against the important hospital pathogen Pseudomonas aeruginosa is variable, due to the potential presence of other resistance mechanisms in addition to β-lactamase production. Synergy was observed for<unk>  with<unk>  in the Burkholderia cepacia complex.
Ceftazidime/avibactam
Imipenem/cilastatin
Imipenem/cilastatin/relebactam
Ampicillin/sulbactam
Avibactam
Piperacillin/tazobactam
Meropenem
Ceftolozane/tazobactam