<unk>  <unk>  is a common infection caused by a group of enteroviruses. It typically begins with a fever and feeling generally unwell. This is followed a day or two later by flat discolored spots or bumps that may blister, on the<unk> s, feet and<unk>  and occasionally buttocks and groin. Signs and symptoms normally appear 3–6 days after exposure to the virus. The rash generally resolves on its own in about a week. Fingernail and toenail loss may occur a few weeks later, but they will regrow with time. The viruses that cause<unk>  are spread through close personal contact, through the air from coughing and the feces of an infected person. Contaminated objects can also spread the<unk> . Coxsackievirus A16 is the most common cause, and enterovirus 71 is the second-most common cause. Other strains of coxsackievirus and enterovirus can also be responsible. Some people may carry and pass on the virus despite having no symptoms of<unk> . Other animals are not involved. Diagnosis can often be made based on symptoms. Occasionally, a throat or stool sample may be tested for the virus.<unk> washing may prevent spread, and those infected should not go to work, daycare or school. No antiviral medication or vaccine is available, but development efforts are underway. Most cases require no specific treatment. Simple pain medication such as ibuprofen or numbing<unk>  gel may be used. Occasionally, intravenous fluids are given to children who are unable to drink enough. Rarely, viral meningitis or encephalitis may complicate the<unk> .<unk>  occurs in all areas of the world. It often occurs in small outbreaks in nursery schools or kindergartens. Large outbreaks have been occurring in Asia since 1997. It usually occurs during the spring, summer and fall<unk> s. Typically it occurs in children less than five years old but can occasionally occur in adults.<unk>  should not be confused with<unk> -and-mouth<unk>  (also known as hoof-and-mouth<unk> , which mostly affects livestock.
Hand, foot, and mouth disease
Cowpox
Progressive vaccinia
Chickenpox
Smallpox
Shingles
Sealpox
Mumps