Detection of autoantibodies against<unk>  is part of rheumatoid arthritis (RA) diagnostics, especially in sera negative for rheumatoid factor (RF negative sera). Anti-MCV antibodies are a member of the ACPA family, a group of the so-called antibodies to<unk>  protein/peptide antigens. Rheumatoid arthritis is an autoimmune disorder. Detection of specific autoantibodies (antibodies directed against the body’s own tissue) such as rheumatoid factors and ACPAs may provide indication of the disease. In many cases, autoimmune diagnostics are crucial for diagnosing RA correctly and already in the disease’s early stages, when typical symptoms often are lacking but when medical therapy is most effective.
Mutated citrullinated vimentin
Oncogenic retroviridae protein
Cross-reactive carbohydrate determinants
Isoantibodies
Mutant protein
Immunoreactive trypsinogen
Neutrophil extracellular traps
IgG4-related disease