The first signs of<unk>  occur around a year after infection, as the full-grown female worm prepares to leave the infected person's body. As the worm migrates to its final site – typically the lower leg – some people have allergic reactions, including hives, fever, dizziness, nausea, vomiting, and diarrhea. Upon reaching its destination, the worm forms a fluid-filled blister under the skin. Over several days, the blister grows larger and begins to cause severe burning pain. When an infected person submerges the blister in water to soothe the pain, the blister ruptures revealing the female worm. The wound remains intensely painful as the worm slowly emerges from the wound over the course of several weeks to months. An infected person can harbor multiple worms – up to 40 at a time – which will emerge from separate blisters at the same time. As the worm emerges, the open blister often becomes infected with bacteria, resulting in redness and swelling, the formation of abscesses, or in severe cases gangrene, sepsis or lockjaw. When the secondary infection is near a joint (typically the ankle), the damage to the joint can result in stiffness, arthritis, or contractures.
Dracunculiasis
Naegleriasis
Gnathostomiasis
Ancylostomiasis
Scarabiasis
Mansonelliasis
Porocephaliasis
Pulicosis