The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, O-GlcNAcylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. In the SV40 virus,<unk>  binds to the GC boxes in the regulatory region (RR) of the genome.
Sp1 transcription factor
STAT protein
Winged-helix transcription factors
Origin recognition complex
Mir-590 microRNA precursor family
Core binding factor
Mir-618 microRNA precursor family
Mir-3180 microRNA precursor family