The prognosis for most individuals with KFS is good if the disorder is treated early and appropriately. Activities that can injure the neck should be avoided, as it may contribute to further damage. Other diseases associated with the syndrome can be fatal if not treated, or if found too late to be treatable. In less than 30% of cases, individuals with KFS will present with heart defects. If these heart defects are present, they often lead to a shortened life expectancy, the average being 35–45 years of age among males and 40–50 among females. This condition is similar to the heart failure seen in gigantism.
Klippel–Feil syndrome
Srb's anomaly
Treacher Collins syndrome
Iniencephaly
Klippel–Trénaunay syndrome
Pelger–Huët anomaly
Laurence–Moon syndrome
Langer–Giedion syndrome