A comparison of a healthy condition to GERD Acid reflux is due to poor closure of the lower esophageal sphincter, which is at the junction between the stomach and the esophagus. Factors that can contribute to GERD: * Hiatal hernia, which increases the likelihood of GERD due to mechanical and motility factors. * Obesity: increasing body mass index is associated with more severe GERD. In a large series of 2,000 patients with symptomatic reflux disease, it has been shown that 13% of changes in esophageal acid exposure is attributable to changes in body mass index. Factors that have been linked with GERD, but not conclusively: * Obstructive sleep apnea * Gallstones, which can impede the flow of bile into the duodenum, which can affect the ability to neutralize gastric acid In 1999, a review of existing studies found that, on average, 40% of GERD patients also had H. pylori infection. The eradication of H. pylori can lead to an increase in acid secretion, leading to the question of whether H. pylori-infected GERD patients are any different than non-infected GERD patients. A double-blind study, reported in 2004, found no clinically significant difference between these two types of patients with regard to the subjective or objective measures of disease severity.
medical cause of Chest pain
medical cause of Myocardial infarction
medical cause of Heartburn
complications of Angina
medical cause of Coronary artery disease
medical cause of Pericarditis
medical cause of Heart failure
medical cause of Constrictive pericarditis