<unk>  is a tyrosine kinase inhibitor which inhibits tyrosine kinases, enzymes responsible for the activation of many proteins by signal transduction cascades. Specifically,<unk>  targets the receptor tyrosine kinase c-Kit which is found to be overexpressed or mutated in several types of cancer.<unk>  is also additional targets, it also inhibits the platelet derived growth factor receptor (PDGFR), lymphocyte-specific protein tyrosine kinase (Lck), focal adhesion kinase (FAK) and fibroblast growth factor receptor 3 (FGFR3) as well as CSF1R.<unk>  has been shown to block the replication of SARS-CoV-2 by inhibiting its main protease, 3CLpro.<unk>  showed >200-fold reduction in viral titers in the lungs and nose of mice infected with SARS-CoV-2.
Masitinib
Sunitinib
Axitinib
Abrocitinib
Gilteritinib
Ceritinib
Upadacitinib
Delgocitinib