Like all aminoglycosides,<unk>  does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or by injection into a muscle. Eye drops and ointments<unk>  only,<unk> rex, or combined with dexamethasone, sold as<unk> radex) and nebulised formulations both have low systemic absorption. The formulation for injection is branded Nebcin. The nebulised formulation (brand name<unk> i) is indicated in the treatment of exacerbations of chronic infection with Pseudomonas aeruginosa in people diagnosed with cystic fibrosis.<unk> rex eye drops are a 0.3%<unk>  sterile ophthalmic solution produced by Bausch & Lomb Pharmaceuticals. Benzalkonium chloride 0.01% is added as a preservative. It is available by prescription only in Bulgaria, Hungary, the United States, and Canada. In certain countries, it is available over the counter.<unk> rex and<unk> radex are indicated in the treatment of superficial infections of the eye, such as bacterial conjunctivitis.<unk> , in its injectable form, is also indicated for various severe or life-threatening infections caused by susceptible strains: sepsis, meningitis, lower respiratory tract infections, intra-abdominal infections, skin infections, bone infections, and skin structure infections, complicated and recurrent urinary tract infections. Spectrum of susceptibility<unk>  has a narrow spectrum of activity and is active against Gram-positive Staphylococcus aureus and various Gram-negative bacteria. Clinically,<unk>  is frequently used to eliminate Pseudomonas aeruginosa in cystic fibrosis patients. The following represents the minimum inhibitory concentration (MIC) susceptibility data for a few strains of Pseudomonas aeruginosa: * Pseudomonas aeruginosa - 512 µg/mL ref? * Pseudomonas aeruginosa (ATCC 27853) – 0.5 µg/mL – 2 µg/mL The MIC for Klebsiella pneumoniae, KP-1, is 2.3±0.2 µg/mL at 25 °C unpublished.
Tobramycin
Meropenem
Imipenem/cilastatin/relebactam
Amikacin
Teicoplanin
Resistin
Moxifloxacin
Telithromycin