Different<unk> es are caused by mutations in the CHST6, KRT3, KRT12, PIP5K3, SLC4A11, TACSTD2, TGFBI, and UBIAD1 genes. Mutations in TGFBI which encodes transforming growth factor beta induced cause several forms of<unk> es including granular<unk> , lattice<unk> , epithelial basement membrane<unk> , Reis-Bucklers<unk> , and Thiel–Behnke<unk> .<unk> es may have a simple autosomal dominant, autosomal recessive or rarely X-linked recessive Mendelian mode of inheritance: Name Inheritance Gene locus Gene Superficial<unk> es Meesmann<unk>  AD 12q13, 17q12 KRT3, KRT12 Reis-Bücklers<unk>  AD 5q31 TGFBI Gelatinous drop-like<unk>  AR 1p32 TACSTD2 Stromal<unk> es Macular<unk>  AR 16q22 CHST6 Granular<unk>  AD 5q31 TGFBI Lattice<unk>  AD 5q31, 9q34 TGFBI, GSN (gene) Schnyder<unk>  AD 1p34.1–p36 UBIAD1 Congenital stromal<unk>  AD 12q13.2 DCN Fleck<unk>  AD 2q35 PIP5K3 Posterior<unk> es Fuchs'<unk>  AD 1p34.3,13pTel-13q12.13, 18q21.2–q21.32, 20p13-p12, 10p11.2 COL8A, SLC4A11, TCF8, TCF4 Posterior polymorphous<unk>  AD 20p11.2, 1p34.3-p32.3, 10p11.2 COL8A2, TCF8,OVOL2, GRHL2 Congenital hereditary endothelial<unk>  AR 20p13-p12 SLC4A11
Corneal dystrophy
Macular corneal dystrophy
Congenital cataract
Granular corneal dystrophy
Band keratopathy
Ocular melanosis
Bullous keratopathy
Fundic gland polyposis