The hallmark features of this syndrome are poorly developed fingernails, toenails, and<unk> e (kneecaps). Sometimes, this disease causes the affected person to have either no thumbnails or a small piece of a thumbnail on the edge of the thumb. The lack of development or complete absence of fingernails results from the loss of function mutations in the LMX1B gene. This mutation may cause a reduction in dorsalising signals, which then results in the failure to normally develop dorsal specific structures such as<unk> s and<unk> e. Other common abnormalities include elbow deformities, abnormally shaped pelvic (hip) bones, and kidney disease.
Nail–patella syndrome
Heel pad syndrome
Facial femoral syndrome
Immersion foot syndromes
Runner's knee
Burning feet syndrome
Tennis elbow
Cuboid syndrome