Not all of the<unk>  symptoms are consistently present. They can vary in severity, and additional features can be noted in individuals affected by<unk> . Some of these additional features are: * Polyhydramnios (increased amniotic fluid during pregnancy) and increased nuchal fold during pregnancy * Specific facial features such as a large nose * Severe and sometimes refractory seizures, abnormalities on the magnetic resonance imaging of the brain * Increased 2-oxoglutaric acid in the blood and urine - this compound is made or used by several enzymes * Finger-like thumbs * Visual impairment * Peripheral neuropathy (nerves conducting sensation from extremities to the brain) and insensivity to pain Intellectual impairment is present in all reported cases, but the severity can vary widely. The prognosis in terms of survival also varies greatly from early childhood till adulthood.
DOOR syndrome
Shone's syndrome
Winter-over syndrome
Fountain syndrome
Duane syndrome
Wartenberg's syndrome
Wilkinson's syndrome
Frey's syndrome