Common concept is<unk>  can occur either due to mother cells are decreased themselves in number (aplastic anemia), mother cells are overwhelmed by malignanrt cells (Leukemia, lymphoma, MDS) or they are being sequestrated (spleen)/destroyed (immune) outside bone marrow. The mechanisms for<unk>  differ according to the etiology. For example, in hemophagocytic lymphohistiocytosis (HLH) there is marked inappropriate and ineffective T cell activation that leads to an increased hemophagocytic activity. The T cell activated macrophages engulf erythrocytes, leukocytes, platelets, as well as their progenitor cells. Along with<unk> , HLH is characterized by fever, splenomegaly, and hemophagocytosis in bone marrow, liver, or lymph nodes.
Pancytopenia
Osteopenia
Basopenia
Cytopenia
Leukopenia
Osteodystrophy
Eosinopenia
Lipodystrophy