The sudden eruption of papulonodules usually indistinguishable from common viral warts should suggest this diagnosis. These papulonodules begin on the extremities, especially on the dorsa of the hands and the wrists and may disseminate to involve the entire body, including the face. The papulonodules may vary in size from 2–3 mm to 10 mm in diameter. Pruritus is often associated.<unk>  is linked with an underlying cancer. Malignant acanthosis nigricans may also become evident, many times with the sudden eruption of multiple seborrheic keratoses, known as the sign of Leser-Trélat.<unk>  mandates a search for an underlying malignancy, recognizing that it may be seen in patients with multiple visceral carcinomas. Histologic examination shows uniform and pronounced hyperkeratosis, acanthosis, and<unk>  without epidermal vacuolization, parakeratosis, or eosinophilic inclusions suggestive of viral warts. The sudden quality of the eruption of<unk>  and its anatomic distribution should facilitate distinction from widespread common warts and from epidermodysplasia verruciformis.
Florid cutaneous papillomatosis
Hydroa vacciniforme
Stasis papillomatosis
Keratosis pilaris atrophicans
Granuloma annulare
Diabetic dermadrome
Generalized granuloma annulare
Vitiligo