Complications Because ischemic<unk>  causes the blood to remain in the penis for unusually long periods of time, the blood becomes deprived of oxygen, which can cause damage to the penile tissue. Such damage can result in erectile dysfunction or disfigurement of the penis. In extreme cases, if the penis develops severe vascular disease, the<unk>  can result in penile gangrene. Low-flow<unk>  Causes of low-flow<unk>  include sickle cell anemia (most common in children), leukemia, and other blood dyscrasias such as thalassemia and multiple myeloma, and the use of various drugs, as well as cancers. A genome-wide association study on Brazilian patients with sickle cell disease identified four single nucleotide polymorphisms in LINC02537 and NAALADL2 significantly associated with<unk> . Other conditions such as Fabry's disease, as well as neurologic disorders such as spinal cord lesions and spinal cord trauma<unk>  has been reported in people who have been hanged; see death erection).<unk>  can also be caused by reactions to medications. The most common medications that cause<unk>  are intra-cavernous injections for the treatment of erectile dysfunction (papaverine, alprostadil). Other medication groups reported are antihypertensives, antipsychotics (e.g., chlorpromazine, clozapine), antidepressants (most notably trazodone), anti-convulsant and mood stabilizer drugs such as sodium valproate. Anticoagulants, cantharides (Spanish Fly) and recreational drugs (alcohol, heroin and cocaine) have been associated.<unk>  is also known to occur from bites of the Brazilian wandering spider. High-flow<unk> === *Causes of high-flow<unk>  include blunt trauma to the perineum or penis, with laceration of the cavernous artery, which can generate an arterial-lacunar fistula. *Anticoagulants (heparin and warfarin) *Antihypertensives (i.e., hydralazine, guanethidine and propranolol) *Hormones (i.e., gonadotropin releasing hormone and testosterone)
Priapism
Pseudophobia
Autophobia
Neophobia
Piquerism
Dysorgasmia
Hyperorgasmia
Dysmelia