Use of<unk>  should be avoided in individuals with the following conditions: * Myasthenia gravis * Acute intoxication with alcohol, narcotics, or other psychoactive substances * Ataxia * Severe hypoventilation * Acute narrow-angle glaucoma * Severe liver deficiencies (hepatitis and liver cirrhosis decrease elimination by a factor of 2) * Severe sleep apnea * Hypersensitivity or allergy to any drug in the benzodiazepine class<unk>  is generally considered an inappropriate benzodiazepine for the elderly due to its long elimination half-life and the risks of accumulation. Benzodiazepines require special precaution if used in the elderly, pregnancy, children, alcohol- or drug-dependent individuals and individuals with comorbid psychiatric disorders. Pregnancy The research into the safety of benzodiazepines during pregnancy is limited and it is recommended that use of benzodiazepines during pregnancy should be based on whether the benefits outweigh the risks. If<unk>  is used during pregnancy the risks can be reduced via using the lowest effective dose and for the shortest time possible. Benzodiazepines should generally be avoided during the first trimester of pregnancy.<unk>  and diazepam are considered to be among the safer benzodiazepines to use during pregnancy in comparison to other benzodiazepines. Possible adverse effects from benzodiazepine use during pregnancy include, abortion, malformation, intrauterine growth retardation, functional deficits, carcinogenesis and mutagenesis. Caution is also advised during breast feeding as<unk>  passes into breast milk.
Chlordiazepoxide
Clorazepate
Amobarbital
Phenobarbital
Heptobarbital
Ethyl loflazepate
Tianeptine
Methylphenobarbital