<unk> /CNO is generally treated by a specialist doctor (paediatric rheumatologist) who has experience with patients with<unk> /CNO. Goals of treatment of<unk> /CNO include: * Reduce inflammation * Prevent bone damage and bone deformities * Decrease pain<unk> /CNO is different for each patient. Not every child responds to every treatment. Your doctor may need to try several medications before finding the one that works for your child. In severe cases, doctors may combine medications to treat the disease. Your doctor will work with you and your child to help find the best treatment. For some<unk> /CNO patients, the disease can be managed with non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs are the first line treatment. However, if NSAIDs are not effective, or if your child does not tolerate NSAIDs well, second line treatments are available. First line treatments include Naproxen (Aleve), Celecoxib (Celebrex) Meloxicam (Mobic), Piroxicam (Feldene), Indomethacin (Indocin), Diclofenac (Voltaren) Second line treatments include corticosteroids (Prednisone/Prednisolone), Methotrexate (Otrexup, Rasuvo, Trexall), Sulfasalazine (Azulfidine), Pamidronate (Aredia), Zoledronic acid (Zometa), Adalimumab (Humira), Etanercept (Enbrel), Infliximab (Remicade) These medications are also used in children with other inflammatory and/or bone conditions. Side effects may occur while taking these medications.
Chronic recurrent multifocal osteomyelitis
Neuralgia-inducing cavitational osteonecrosis
Chronic undermining burrowing ulcer
Shoulder injury related to vaccine administration
Skin manifestations of sarcoidosis
Chronic limb threatening ischemia
Intervertebral disc damage and spaceflight
Localized disease