Illustration of how the buildup of lipids cause a blockage of blood flow to the portion of the artery below the narrowing. As previously mentioned, the most common cause of peripheral artery disease, especially in patients over 40 years old, is<unk> .<unk>  is a narrowing of the arteries caused by lipid or fat build up and calcium deposition in the wall of the affected arteries. The most commonly affected site occurs at arterial branch points, because there is an increase in turbulence and stress on the artery at these areas where the artery branches to supply distant structures. Disease of distant structures, including feet and toes, are usually caused by diabetes and seen in the elderly population. Additional mechanisms of peripheral artery disease including arterial spasm, thrombosis, and fibromuscular dysplasia. The mechanism of arterial spasm is still being studied, but it can occur secondary to trauma. The symptoms of claudication ensue when the artery spasms, or clamps down on itself, creating an obstruction. Similar to<unk> , this leads to decreased blood flow to the tissue downstream of the obstruction. Thrombosis, or the formation of a blood clot, occurs usually due stasis or trauma. Damage to the lining of the blood vessel begins the process of clot formation. The blood clot ultimately creates a narrowing in the artery preventing adequate blood flow and oxygen to the tissue further down.
complications of Atherosclerosis
complications of Vasculitis
complications of Coronary thrombosis
medical cause of Stroke
medical cause of Coronary artery aneurysm
complications of Fasciolosis
symptom of Giant cell arteritis
medical cause of Coronary artery disease