Infants born with<unk>  may show no effects, or may display mild effects that often go unrecognized as a problem: excessive sleeping, reduced interest in nursing, poor muscle tone, low or hoarse cry, infrequent bowel movements, significant jaundice, and low body temperature. If the fetal thyroid hormone deficiency is severe because of complete absence (athyreosis) of the gland, physical features may include a larger anterior fontanel, persistence of a posterior fontanel, an umbilical hernia, and a large tongue (macroglossia). In the era before newborn screening, less than half of cases of severe<unk>  were recognized in the first month of life. As the months proceeded, these babies would grow poorly and be delayed in their development. By several years of age, they would display the recognizable facial and body features of cretinism. Persistence of severe, untreated<unk>  resulted in severe mental impairment, with an IQ below 80 in the majority. Most of these<unk> ildren eventually ended up in institutional care. File:CDpic3.3-month-old infant with untreated<unk> ; picture demonstrates hypotonic posture, myxedematous facies, macroglossia, and umbilical hernia File:CDpic1.Close up of face, showing myxedematous facies, macroglossia, and skin mottling File:CDpic2.Close up showing abdominal distension and umbilical hernia. File:Cretinnen aus Steiermark, 1819 gez. Loder, gest. Leopold Müller.Congenital<unk> , copper engraving, 1815
Congenital hypothyroidism
Congenital iodine deficiency syndrome
Congenital adrenal hyperplasia
Thyroid dysgenesis
Late onset congenital adrenal hyperplasia
Lipoid congenital adrenal hyperplasia
Congenital hyperinsulinism
Isolated growth hormone deficiency