<unk> " is a feature identified by Dr. Hyman Isaac<unk>  (1887–1954), an American physician and medical historian. A greater distance separates the largest two<unk> s of some people exhibiting Down syndrome or cretinism."
Goldstein's toe sign
White hand sign
Bing's sign
Hannington-Kiff sign
Thumbprint sign
De Musset's sign
Claybrook sign
Crichton-Browne sign