Keratoderma blennorrhagicum due to<unk>  * Because common systems involved include the eye, the urinary system, and the hands and feet, one clinical mnemonic in<unk>  is "Can't see, can't pee, can't climb a tree." * The classic triad consists of: * Conjunctivitis * Nongonococcal urethritis * Asymmetric oligoarthritis * Symptoms generally appear within 1–3 weeks but can range from 4 to 35 days from the onset of the inciting episode of the disease. * The classical presentation of the syndrome starts with urinary symptoms such as burning pain on urination (dysuria) or an increased frequency of urination. Other urogenital problems may arise such as prostatitis in men and cervicitis, salpingitis and/or vulvovaginitis in women. * It presents with monoarthritis affecting the large joints such as the knees and sacroiliac spine causing pain and swelling. An asymmetrical inflammatory arthritis of interphalangeal joints may be present but with relative sparing of small joints such as the wrist and hand. * Patient can have enthesitis presenting as heel pain, Achilles tendinitis or plantar fasciitis, along with balanitis circinata (circinate balanitis), which involves penile lesions present in roughly 20 to 40 percent of the men with the disease. * A small percentage of men and women develop small hard nodules called keratoderma blennorrhagicum on the soles of the feet and, less commonly, on the palms of the hands or elsewhere. The presence of keratoderma blennorrhagica is diagnostic of<unk>  in the absence of the classical triad. Subcutaneous nodules are also a feature of this disease. * Ocular involvement (mild bilateral conjunctivitis) occurs in about 50% of men with urogenital<unk>  syndrome and about 75% of men with enteric<unk>  syndrome. Conjunctivitis and uveitis can include redness of the eyes, eye pain and irritation, or blurred vision. Eye involvement typically occurs early in the course of<unk> , and symptoms may come and go. * Dactylitis, or "sausage digit", a diffuse swelling of a solitary finger or toe, is a distinctive feature of<unk>  and other peripheral spondylarthritides but can also be seen in polyarticular gout and sarcoidosis. * Mucocutaneous lesions can be present. Common findings include oral ulcers that come and go. In some cases, these ulcers are painless and go unnoticed. In the oral cavity, the patients may suffer from recurrent aphthous stomatitis, geographic tongue and migratory stomatitis in higher prevalence than the general population. * Some patients suffer serious gastrointestinal problems similar to those of Crohn's disease. * About 10 percent of people with<unk> , especially those with a prolonged course of the disease, will develop cardiac manifestations, including aortic regurgitation and pericarditis.<unk>  has been described as a precursor of other joint conditions, including ankylosing spondylitis.
Reactive arthritis
Behçet's disease
Rheumatoid arthritis
Septic arthritis
Psoriatic arthritis
Plantar fasciitis
Inflammatory arthritis
Rheumatism