<unk> s, often referred to by the media and in the general population as ocular<unk> s, may arise from any of the three parts of the<unk>  and are sometimes referred to by their location, choroidal<unk> , ciliary body<unk> , or iris<unk> . Large tumors often encompass multiple parts of the<unk> and can be named accordingly. True iris<unk> s, originating from within the iris as opposed to originating elsewhere and invading the iris, are distinct in their etiology and prognosis, such that the other tumors are often referred to collectively as posterior<unk> s. Iris<unk> <unk>  tumors can originate from melanocytes residing within the iris. Benign melanocytic tumors, such as iris freckles and moles (nevi), are common and pose no health risks, unless they show signs of malignancy, in which case they are classified as iris<unk> s. Though derived from<unk>  melanocytes, iris<unk> s share more in common with cutaneous (skin)<unk> s in that they frequently harbor BRAF mutations associated with ultraviolet damage. Iris<unk> s are much less likely to metastasize than other<unk> s, and less likely to impair vision if detected and treated early. Approximately 5% of<unk> s involve the iris. Posterior<unk>  Variably pigmented, mushroom-shaped choroidal tumor has ruptured the Bruch membrane and grown into the subretinal space. Benign melanocytic tumors of the choroid, such as choroidal freckles and nevi, are very common and pose no health risks, unless they show signs of malignancy, in which case they are considered<unk> s.<unk>  is distinct from most skin<unk> s associated with ultraviolet exposure; however, it shares several similarities with non-sun-exposed<unk> s, such as acral<unk> s and mucosal<unk> s. BRAF mutations are extremely rare in posterior<unk> s; instead,<unk> s frequently harbor GNAQ/GNA11 mutations, a trait shared with blue nevi, nevus of Ota, and ocular melanosis. As seen in BRAF, mutations in GNAQ/GNA11 are early events in tumorigenesis and are not prognostic for tumor stage or later metastatic spread. In contrast, mutations in the gene BAP1 are strongly linked to metastatic spread and patient survival. Incidence of posterior<unk>  is highest among people with light skin and blue eyes. Other risk factors, such as blue light exposure and arc welding, have been put forward, but are still debated in the field. Mobile phone use is not a risk factor for<unk> . Malignant<unk>  of the choroid
Uveal melanoma
Diabetic retinopathy
Otosclerosis
Radiation retinopathy
Autoimmune retinopathy
Vitreoretinopathy
Diabetic papillopathy
Sickle cell retinopathy