<unk>  (developmental code names GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the nonsteroidal antiandrogen bicalutamide as a lead compound.<unk>  is an orally active partial agonist of the androgen receptor (AR). In intact male rats, 0.5 mg<unk>  daily was shown to reduce prostate weight to 79.4%, and non-significantly increased levator ani muscle weight. In castrated male rats, this dose restored only 32.5% prostate weight, but 101% levator ani muscle weight This suggests that<unk>  is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist actions at the androgen receptor prevent the side effects associated with the antiandrogens traditionally used for treatment of BPH.
Andarine
Chlormerodrin
Hysterothylacium
Oleandrin
Protollin
Catechol estrogen
Gestodene
Chlordane