Disseminating<unk>  cells can proliferate or become dormant depending on the microenvironment and factors such as the ERK/p38 ratio.<unk>  is a stage in<unk>  progression where the cells cease dividing but survive in a quiescent state while waiting for appropriate environmental conditions to begin proliferation again. Quiescence is the state where cells are not dividing but at arrest in the cell cycle in G0-G1. Dormant<unk>  cells are thought to be present in early tumor progression, in micrometastases, or left behind in minimal residual disease (MRD) after what was thought to be a successful treatment of the primary tumor.
Cancer dormancy
Tumor initiation
Tumor promotion
Carcinogenesis
Stem cell doping
Malignant 
Breast cancer management
Tumor progression