<unk>  is a rare autosomal recessive disorder of<unk>  metabolism. After phenylketonuria,<unk>  is the second most common disorder of amino acid metabolism. The disease is caused by defects in the<unk>  cleavage system, an enzyme responsible for<unk>  catabolism. There are several forms of the disease, with varying severity of symptoms and time of onset. The symptoms are exclusively neurological in nature, and clinically this disorder is characterized by abnormally high levels of the amino acid<unk>  in bodily fluids and tissues, especially the cerebrospinal fluid.<unk>  is sometimes referred to as "nonketotic hyperglycinemia" (NKH), as a reference to the biochemical findings seen in patients with the disorder, and to distinguish it from the disorders that cause "ketotic hyperglycinemia" (seen in propionic acidemia and several other inherited metabolic disorders). To avoid confusion, the term<unk> " is often used, as this term more accurately describes the clinical symptoms of the disorder.
Glycine encephalopathy
Toxic encephalopathy
Ethylmalonic encephalopathy
Wernicke encephalopathy
Post-encephalitic parkinsonism
Early myoclonic encephalopathy
Carbamate poisoning
Viral encephalitis