Like many ACE inhibitors, this prodrug is converted to the active metabolite<unk> at following oral administration. Unlike other members of the group, it is eliminated both by renal and hepatic routes, which may allow for greater use in patients with renal impairment. However, data on its effect upon the renal function are conflicting.
Spirapril
Racecadotril
Moexipril
Ramipril
Ambrisentan
Bosentan
Macitentan
Isosorbide dinitrate