Babies born with Jarcho-Levin may be very healthy and grow up to lead normal lives. However, many individuals with Jarcho-Levin suffer from problems of respiratory insufficiency secondary to volume-restricted thoraces. These individuals will often develop pulmonary complications and die in infancy or early childhood. The disparity in outcomes of those with the syndrome is related to the fact that Jarcho-Levin actually encompasses two or more distinct syndromes, each with its own range of prognoses. The syndromes currently recognized as subtypes of Jarcho-Levin are termed spondylothoracic dysplasia and<unk> . The disease is related to the SRRT gene.
Spondylocostal dysostosis
Acrofrontofacionasal dysostosis
Spondyloepimetaphyseal dysplasia
Infantile cortical hyperostosis
Cleidocranial dysostosis
Pycnodysostosis
Spondyloepiphyseal dysplasia congenita
Acrodysostosis