Immunophenotyping<unk> s of mice and humans have consistent immunophenotypes, including FcεRI+, CD123, CD49b(DX-5)+, CD69+, Thy-1.2+, 2B4+, CD11bdull, CD117(c-kit)−, CD24−, CD19−, CD80−, CD14−, CD23−, Ly49c−, CD122−, CD11c−, Gr-1−, NK1.1−,<unk> 220−, CD3−, γδTCR−, αβTCR−, α4 and β4-integrin negative. Recently, Heneberg proposed that<unk> s may<unk> e defined as the cellular population positive for CD13, CD44, CD54, CD63, CD69, CD107a, CD123, CD164, CD193/ CCR3, CD203c, TLR-4, and FcεRI. When activated, some additional surface markers are known to<unk> e upregulated (CD13, CD107a, CD164), or surface-exposed (CD63, and the ectoenzyme CD203c). Allergy Diagnosis<unk> s are easily isolated from venous<unk> lood and present good “indicator cells” of an IgE-mediated allergic response<unk> ased on the upregulation of activation markers such as CD63 and/or CD203c upon suspect allergen stimulation. Therefore, the<unk> AT serves to confirm IgE-mediated allergy following uncertain results from classical testing<unk> ased on anamnesis, skin testing or specific IgE results. More recently,<unk> AT has also<unk> een used for the monitoring of successful allergen immunotherapy (desensitization) to differentiate short-term desensitization versus sustained unresponsiveness to the allergen.
Basophil
Monocyte
Prolymphocyte
Thymocyte
Podocyte
Mast cell
Dendritic cell
Natural killer cell