Most common adverse effects are diarrhea (5%), nausea (3%), abdominal pain (3%), and vomiting. Fewer than 1% of people stop taking the drug due to side effects. Nervousness, skin reactions, and anaphylaxis have been reported. Clostridium difficile infection has been reported with use of<unk> .<unk>  does not affect the efficacy of birth control unlike some other antibiotics such as rifampin. Hearing loss has been reported. Occasionally, people have developed cholestatic hepatitis or delirium. Accidental intravenous overdose in an infant caused severe heart block, resulting in residual encephalopathy. In 2013 the FDA issued a warning that<unk>  "can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm." The FDA noted in the warning a 2012 study that found the drug may increase the risk of death, especially in those with heart problems, compared with those on other antibiotics such as amoxicillin or no antibiotic. The warning indicated people with preexisting conditions are at particular risk, such as those with QT interval prolongation, low blood levels of potassium or magnesium, a slower than normal heart rate, or those who use certain drugs to treat abnormal heart rhythms. It has been reported that<unk>  blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.
Azithromycin
Dirithromycin
Telithromycin
Roxithromycin
Levofloxacin
Moxifloxacin
Amoxicillin
Gemifloxacin