<unk>  normally results from direct skin contact with<unk> gens, although ingestion and inhalation are also possible causative routes.<unk> gens are fat-soluble, meaning they persist in the body fat for a very long period following exposure.<unk>  is a chronic inflammatory condition that results from this persistence, in combination with the toxin's chemical properties. It is believed, at least from rodent models, that the toxin activates a series of receptors promoting macrophage proliferation, inducing neutrophilia and leading to a generalised inflammatory response in the skin. This process may also be augmented by induction of excess tumor necrosis factor in the blood serum. The inflammatory processes lead to the formation of keratinous plugs in skin pores, forming yellowish cysts and dark pustules. The associated pus is usually a color of green approximating that of a tennis ball. The skin lesions occur mainly in the face, but in more severe cases they involve the shoulders and chest, the back, and the abdomen. In advanced cases, the lesions appear also on the arms, neck, thighs, legs, hands and feet. In some instances,<unk>  may not appear for three to four weeks after toxic exposure; however, in other cases—particularly in events of massive exposure—the symptoms may appear within days.
Chloracne
Lacnunga
Mersa
Shiatsu
Laudanum
Scyllatoxin
Allergic salute
Ephedra 