The<unk>  <unk>  is a nucleoprotein complex of viral genetic material and associated viral and host proteins which is capable of inserting a viral genome into a host genome. The<unk>  forms after uncoating of a viral particle after entry into the host cell. In the case of the human immunodeficiency virus (HIV), the<unk>  forms after the Reverse Transcription Complex (RTC) has reverse transcribed the viral RNA into DNA. The<unk>  consists of viral proteins (including Vpr, matrix and integrase), host proteins (including Barrier to autointegration factor 1) and the viral DNA. The<unk>  enters the cellular nucleus through the nuclear pore complex without disrupting the nuclear envelope, thus allowing HIV and related retroviruses to replicate in non-dividing cells. Following nuclear entry, the<unk> 's DNA payload may be integrated into the host DNA as a "provirus".
Pre-integration complex
Replicon 
Exosome 
Cis-regulatory element
Origin recognition complex
Insertion sequence
Active chromatin sequence
Mutanome