The tumour arises from the cells of the proximal renal tubular epithelium. It is considered an adenocarcinoma. There are two subtypes: sporadic (that is, non-hereditary) and hereditary. Both such subtypes are associated with mutations in the short-arm of chromosome 3, with the implicated genes being either tumour suppressor genes (VHL and TSC) or oncogenes (like c-Met).
Renal cell carcinoma
Renal medullary carcinoma
Renal oncocytoma
Papillary renal cell carcinoma
Renal anaplastic sarcoma
Renal medullary fibroma
Clear cell renal cell carcinoma
Clear cell papillary renal cell carcinoma