<unk>  is a term used synonymously with severe hypothyroidism. However, the term is also used to describe a dermatological change that can occur in hyperthyroidism and (rare) paradoxical cases of hypothyroidism. In this latter sense,<unk>  refers to deposition of mucopolysaccharides in the dermis, which results in swelling of the affected area. One manifestation of<unk>  occurring in the lower limb is pretibial<unk> , a hallmark of Graves disease, an autoimmune form of hyperthyroidism.<unk>  can also occur in Hashimoto thyroiditis and other long-standing forms of hypothyroidism. The word<unk>  originates from , taken from ancient Greek to convey 'mucus' or 'slimy substance', and for "swelling". It can also be thought as nonpitting edema, in contrast to pitting edema.
Myxedema
Lipedema
Venospasm
Leukoedema
Peripheral edema
Picardy sweat
Edema
Vasospasm