Chromosome 13, the affected chromosome in this disease. alt Of those fetuses that do survive to gestation and birth, common abnormalities may include: * Nervous system * Intellectual disability and motor disorder * Microcephaly * Holoprosencephaly (failure of the forebrain to divide properly) and associated facial deformities such as cyclopia * Structural eye defects, including microphthalmia, Peters' anomaly, cataract, iris or fundus (coloboma), retinal dysplasia or retinal detachment, sensory nystagmus, cortical visual loss, and optic nerve hypoplasia * Meningomyelocele (a spinal defect) * Musculoskeletal and cutaneous * Polydactyly (extra digits) * Proboscis * Congenital trigger digits * Low-set ears * Prominent heel * Deformed feet known as rocker-bottom feet * Omphalocele (abdominal defect) * Abnormal palm pattern * Overlapping of fingers over thumb * Cutis aplasia (missing portion of the skin/hair) * Cleft palate * Urogenital * Abnormal genitalia * Kidney defects * Other * Heart defects (ventricular septal defect) (Patent Ductus Arteriosus) * Dextrocardia * Single umbilical artery
Patau syndrome
Bart syndrome
McGillivray syndrome
Sotos syndrome
Keutel syndrome
Cortes Lacassie syndrome
Bart–Pumphrey syndrome
Fryns-Aftimos syndrome