If percutaneous coronary intervention (PCI) is not available within 90–120 minutes of first contact,<unk>  is recommended intravenously as soon as possible after the onset of a ST elevation myocardial infarction (STEMI). As<unk>  is a bacterial product, the body has the ability to build up an immunity to it. Therefore, it is recommended that this medication should not be used again after four days from the first administration, as it may not be as effective and can also cause an allergic reaction. For this reason, it is usually given only for a person's first heart attack. Further thrombotic events could be treated with tissue plasminogen activator (tPA). Overdose of<unk>  or tPA can be treated with aminocaproic acid.
Streptokinase
Thrombin
Serpin
Fibrinolysin
Prothrombinase
Angiozyme
Ocriplasmin
Coagulase