Congeners<unk>  congers are important in drug discovery and development due to multiple actions on different targets. They have ability to inhibit Cav2.2 channel, modulate and inhibit subunits of nAChr selectively such as α9α10, α3β4 and potentiate GABAA activity.
Coronaridine
Nortilidine
Iofetamine 
Lofexidine
Adenosine
Ivabradine
Veratridine
Maprotiline