<unk>  refers to a mouth that is unusually wide. The term is from the Greek prefix makro- meaning "large" and from Greek στόμα, "mouth".<unk>  is characterized as a physical abnormality that causes clefts to form on the face of affected individuals. These clefts can form on either or both sides of the face, but they are most commonly seen on the right cheek and have a higher rate of occurrence in males.<unk>  is very irregular and on average occurs only once in every 150,000 to 300,000 live births. It's unusual for<unk>  to occur on its own and it is included as a symptom for many diseases including craniofacial microsomia. The clefts result from improper development and fusion of the mandibular and maxillary processes. The clefts cause problems with facial muscle development. The origin of<unk>  is not yet fully understood it could have multiple causes.
Macrostomia
Microcoria
Microdontia
Acrania
Macrodontia 
Macrocephaly
Spotted lunulae
Oxycephaly