The cause and pathogenesis of this<unk>  condition are not very well understood. Several factors have been postulated: * Formation of a hard salivary calculus or sialolith by accumulation of calcium salts in the duct of the salivary gland (a process known as Sialolithiasis). This has been proposed as the most common cause for Küttner's tumor of the submandibular gland, with sialoliths observed in an appreciable proportion of cases. However, sialolith involvement may not be found in many cases. * Abnormalities of the salivary gland ducts leading to excessive accumulation or retention of ductal secretions, which can excite<unk>  inflammations. * Immune, especially autoimmune, cause - which has gained steam, given the observation that the tissue of the glands is overrun with lymphoid immune cells and fibrous connective tissue, as well as corroboration from markedly similar lesions (with histologic and immunohistochemical findings) seen elsewhere in the body. The presence of abundant Immunoglobulin G4 (IgG4) associated with Plasma cells infiltrating into the salivary glands, as well as increased serum IgG4 concentration, has been noted with patients with Küttner's tumor. This<unk>  condition is primarily observed in adult (40–70 years) patients. However, Küttner's tumor, with prominent immunopathological features, has been described in an 11-year-old boy in Brazil in 2012.
Chronic sclerosing sialadenitis
Tuberculous gumma
Necrotizing sialometaplasia
Laryngeal papillomatosis
Denture-related stomatitis
Acute necrotizing ulcerative gingivitis
Idiopathic facial aseptic granuloma
Airsacculitis