Side effects include blurred vision, nausea, vomiting, abdominal cramps, headache, diarrhoea, swelling legs/ankles, shortness of breath, pale lips/nails/skin, muscle weakness, easy bruising/bleeding, hearing and mental problems. * Unwanted/uncontrolled movements (including tongue and face twitching) * Deafness or tinnitus. * Nausea, vomiting, diarrhoea, abdominal cramps * Headache. * Mental/mood changes (such as confusion, personality changes, unusual thoughts/behavior, depression, feeling being watched, hallucinating) * Signs of serious infection (such as high fever, severe chills, persistent sore throat) * Skin itchiness, skin color changes, hair loss, and skin rashes. *<unk> -induced itching is very common among black Africans (70%), but much less common in other races. It increases with age, and is so severe as to stop compliance with drug therapy. It is increased during malaria fever; its severity is correlated to the malaria parasite load in blood. Some evidence indicates it has a genetic basis and is related to<unk>  action with opiate receptors centrally or peripherally. * Unpleasant metallic taste * This could be avoided by "taste-masked and controlled release" formulations such as multiple emulsions. *<unk>  retinopathy * Electrocardiographic changes * This manifests itself as either conduction disturbances (bundle-branch block, atrioventricular block) or Cardiomyopathy – often with hypertrophy, restrictive physiology, and congestive heart failure. The changes may be irreversible. Only two cases have been reported requiring heart transplantation, suggesting this particular risk is very low. Electron microscopy of cardiac biopsies show pathognomonic cytoplasmic inclusion bodies. * Pancytopenia, aplastic anemia, reversible agranulocytosis, low blood platelets, neutropenia. Pregnancy<unk>  has not been shown to have any harmful effects on the fetus when used in the recommended doses for malarial prophylaxis. Small amounts of<unk>  are excreted in the breast milk of lactating women. However, this drug can be safely prescribed to infants, the effects are not harmful. Studies with mice show that radioactively tagged<unk>  passed through the placenta rapidly and accumulated in the fetal eyes which remained present five months after the drug was cleared from the rest of the body. Women who are pregnant or planning on getting pregnant are still advised against traveling to malaria-risk regions. Elderly There is not enough evidence to determine whether<unk>  is safe to be given to people aged 65 and older. Since it is cleared by the kidneys, toxicity should be monitored carefully in people with poor kidney functions.
Chloroquine
Primaquine
Amodiaquine
Artemether
Tafenoquine
Piperaquine
Ajmalicine
Mefloquine