Amygdala (in red) brain structures linked to<unk>  disorders The pathophysiology of<unk>  is an active and ongoing area of research often involving the intersection of genetics and neurological structures.<unk>  has been linked to changes in functional connectivity of the amygdala and its processing of fear and<unk> . Sensory information enters the amygdala through the nuclei of the basolateral complex (consisting of lateral, basal and accessory basal nuclei). The basolateral complex processes the sensory-related fear memories and communicates information regarding threat importance to memory and sensory processing elsewhere in the brain, such as the medial prefrontal cortex and sensory cortices. Neurological structures traditionally appreciated for their roles in<unk>  include the amygdala, insula and orbitofrontal cortex (OFC). It is broadly postulated that changes in one or more of these neurological structures are believed to allow greater amygdala response to emotional stimuli in individuals who have<unk>  as compared to individuals who do not have<unk> . Individuals with<unk>  have been suggested to have greater amygdala and medial prefrontal cortex (mPFC) activation in response to stimuli than individuals who do not have<unk> . However, the exact relationship between the amygdala and the frontal cortex (e.g., prefrontal cortex or the orbitofrontal cortex (OFC)) is not fully understood because there are studies that suggest increased or decreased activity in the frontal cortex in individuals who have<unk> . Consequently, because of the tenuous understanding of the frontal cortex as it relates to the amygdala in individuals who have<unk> , it's an open question as to whether individuals who have<unk>  bear an amygdala that is more sensitive than an amygdala in an individual without<unk>  or whether frontal cortex hyperactivity is responsible for changes in amygdala responsiveness to various stimuli. Recent studies have attempted to identify specific regions of the frontal cortex (e.g., dorsomedial prefrontal cortex (dmPFC)) that may be more or less reactive in individuals who have<unk>  or specific networks that may be differentially implicated in individuals who have<unk> . Other lines of study investigate whether activation patterns vary in individuals who have<unk>  at different ages with respect to individuals who do not have<unk>  at the same age (e.g., amygdala activation in adolescents with<unk> .
Generalized anxiety disorder
Hypochondriasis
Separation anxiety disorder
Social anxiety disorder
Blood phobia
Medication phobia
Anxiety disorder
Somatization disorder