It may or may not be a precancerous indication associated with later malignancy, but the level of appropriate concern is highly dependent on the context with which it is diagnosed. For example, already differentiated, specialised cells such as epithelia displaying "cellular<unk> " are far less likely to become problematic cancerous/ malignant than are myeloid progenitor cells of the immune system. The 'further back' in an already specialised, differentiated cell's lineage, the more problematic cellular<unk>  is likely to be. This is due to the conferring of such<unk>  to progeny-cells further down the lineage of that cell type.
Atypia
Zoobiquity
Hyperplasia
Lobulation
Bizarre ER
Bookmarking
Pleomorphism 
Nuclear atypia