<unk> , sold under the brand name Trulicity among others, is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. It is also approved in the United States for the reduction of major adverse cardiovascular events in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors. It is a once-weekly injection. The most common side effects are nausea, diarrhea, vomiting, abdominal pain, and decreased appetite. It is a glucagon-like peptide-1 receptor agonist (GLP-1 agonist) consisting of GLP-1(7-37) covalently linked to an Fc fragment of human IgG4. GLP-1 is a hormone that is involved in the normalization of level of glucose in blood (glycemia). The Food and Drug Administration (FDA) approved<unk>  for use in the United States in September 2014. It was approved for use in the European Union in November 2014. In 2019, it was the 134th most commonly prescribed medication in the United States, with more than 5million prescriptions.
Dulaglutide
Semaglutide
Albiglutide
Teduglutide
Liraglutide
Exenatide
Linagliptin
Saxagliptin