Genetics Two-thirds of families with a history of diabetes type 2 report more than one family member having<unk> . There is a higher risk of fibrosis for family members where someone was diagnosed with NASH. Asian populations are more susceptible to metabolic syndrome and<unk>  than their western counterparts. Hispanic persons have a higher prevalence of<unk>  than white individuals, whereas the lowest prevalence is observed in black individuals.<unk>  is twice as prevalent in men compared to women, which might be explained by lower levels of estrogen in men. Genetic variations in two genes are associated with<unk> :<unk> -synonymous single-nucleotide polymorphisms (SNPs) in PNPLA3 and TM6SF2. Both correlate with<unk>  presence and severity, but their roles for diagnosis remain unclear. Although<unk>  has a genetic component, the American Association for the Study of Liver<unk> s (AASLD) does not recommend screening family members as there is not enough confirmation of heritability, although there is some evidence from familial aggregation and twin studies. Diet According to the Asia-Pacific Working Group (APWG) on<unk> , overnutrition is a major factor of<unk>  and NASH, particularly for lean<unk> . Diet composition and quantity, in particular omega-6<unk>  acid and fructose, have important roles in<unk>  progression from<unk> to NASH and fibrosis. Choline deficiency can lead to the development of<unk> . Lifestyle Habitual snoring may be a risk factor for<unk> , even after accounting for established risk factors in individuals. Severe cases of snoring lead to airway blockage or difficulty breathing when sleeping, and usually signals the presence of obstructive sleep apnea (OSAS), a much more serious breathing condition. Blockage or narrowing of the airways, even temporarily, can cause the body to experience lowered oxygen levels in the blood, and these conditions of hypoxia are recurring in those with obstructive sleep apnea (OSAS). Constant hypoxia may cause a variety of changes within the body, such as tissue inflammation, increased insulin resistance, and liver injury. A prospective cohort study found the association between habitual snoring and<unk>  development to be significant, and the trend was noted to be most prominent in lean individuals.
Non-alcoholic fatty liver disease
Metabolic syndrome
Alcoholic liver disease
Alcoholic hepatitis
Fatty liver disease
Autoimmune hepatitis
Viral hepatitis
Polycystic liver disease