<unk>  lacks the side effects that most JAK inhibitors have in humans; instead, side effects are infrequent, mild, and mostly self-limiting. The most common side effects are gastrointestinal problems (vomiting, diarrhea, and appetite loss) and lethargy. The GI problems can sometimes be alleviated by giving<unk>  with food. New cutaneous or subcutaneous lumps, such as papillomas, can appear, and dogs face an increased susceptibility to infections such as demodicosis. There is a transient decrease in neutrophils, eosinophils, and monocytes, as well as in serum globulin, while cholesterol and lipase levels increase. The decrease in white blood cells lasts only around 14 days. None of the increases or decreases are clinically significant (i.e. none push their corresponding values out of normal ranges). Less common side effects of<unk>  include bloody diarrhea; pneumonia; infections of the skin, ear, and/or urinary tract; and histiocytomas (benign tumors). Increases in appetite, aggression, and thirst have also been reported.<unk>  is more likely to cause side effects if given twice a day than if given once a day. Some dogs transitioning from twice-a-day to once-a-day dosing have gotten a temporary increase in itchiness.
Oclacitinib
Abrocitinib
Upadacitinib
Baricitinib
Erdafitinib
Delgocitinib
Gilteritinib
Dacomitinib