The<unk>  Investigation and OnLine Information Network<unk>  is the largest web-based<unk><unk>  and analysis system.<unk>  currently contains over 3,000<unk> s or<unk>  candidates for over 190 pathogens. The<unk>  information in the<unk>  is collected by manual curation from over 1,600 peer-reviewed papers. Different from most existing<unk><unk> s,<unk>  focuses on<unk>  research data. Different types of information is curated, including<unk>  name, license status, antigens used,<unk>  adjuvants,<unk>  vectors,<unk> tion procedure, host immune response, challenge procedure,<unk>  efficacy, adverse events, etc. All<unk>  information in the<unk>  is supported by quoted references. The data generated by a curator is published only after a careful review and approval by a<unk>  domain expert. In addition,<unk>  includes many<unk>  analysis programs. For example,<unk>  includes Vaxign (http://www.violinet.org/vaxign), the first web-based<unk>  design program based on the strategy of reverse<unk> logy. Vaxign has been tested in different pathogen models, including uropathogenic E. coli and Brucella spp.<unk>  also maintains the official web page for the development of community-based<unk>  Ontology (VO) (http://www.violinet.org/vaccineontology). VO is a formal biomedical ontology in the domain of<unk>  and<unk> tion. VO is targeted for<unk>  data standardization and integration, and supporting automated reasoning. VO has been shown to enhance<unk>  literature mining.
VIOLIN vaccine database
Australian Vaccination-risks Network
Timeline of human vaccines
Functional molecular infection epidemiology
SmiNet
Guatemala syphilis experiments
Disease registry
Vaccine vial monitor