Common causes include bilateral adrenalectomy for the treatment of Cushing's disease, and hypopituitarism. The onset of the disease can occur up to 24 years after a bilateral adrenalectomy has been performed, with an average of up to 15 years after. A preventative measure that can be utilized is prophylactic radiotherapy when a bilateral adrenalectomy is being performed in order to prevent<unk>  from manifesting. Screening can also be done with the help of an MRI in order to visualize the pituitary for tumors. If tumors are not present then an MRI should be performed at intervals. Hyper-pigmentation and fasting ACTH levels within plasma above 154 pmol/l are predictive of<unk>  after an adrenalectomy. Risk factors include being younger in age and pregnancy.
Nelson's syndrome
Mendelson's syndrome
Fowler's syndrome
Schwartz–Matsuo syndrome
Coffin–Lowry syndrome
Young–Simpson syndrome
Grisel's syndrome
Renpenning's syndrome