<unk>  <unk> , also known as<unk> c age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocappillaris) which can lead to a loss of visual function over time. It is estimated that<unk>  affects >5 million people worldwide and approximately 1 million patients in the US, which is similar to the prevalence of neovascular (wet) AMD, the other advanced form of the disease. The incidence of advanced AMD, both<unk>  and neovascular AMD, increases exponentially with age and while there are therapies for wet AMD,<unk>  currently has no approved treatment options. The aim of most current clinical trials is to reduce the progression of<unk>  lesion enlargement.
Geographic atrophy
Posterior cortical atrophy
Neurofibrillary tangle
Hippocampal sclerosis
Central chromatolysis
Amyloid plaques
Pellucid marginal degeneration
Superficial siderosis