<unk> , or EEC, and also referred to as EEC syndrome and split hand–split foot–ectodermal dysplasia–cleft syndrome is a rare form of<unk>  dysplasia, an autosomal dominant disorder inherited as a genetic trait. EEC is characterized by the triad of<unk> ,<unk>  dysplasia, and facial<unk> s. Other features noted in association with EEC include vesicoureteral reflux, recurrent urinary tract infections, obstruction of the nasolacrimal duct, decreased pigmentation of the hair and skin, missing or abnormal teeth, enamel hypoplasia, absent punctae in the lower eyelids, photophobia, occasional cognitive impairment and kidney anomalies, and conductive hearing loss.
Ectrodactyly–ectodermal dysplasia–cleft syndrome
Greig cephalopolysyndactyly syndrome
Saethre–Chotzen syndrome
Renal dysplasia-limb defects syndrome
Pelger–Huët anomaly
Tricho–rhino–phalangeal syndrome type 2
Goldberg–Shprintzen syndrome
Short rib–polydactyly syndrome