<unk><unk><unk><unk>  (HEV<unk>  is<unk> -frequency,<unk><unk><unk>  in the violet/blue band from 400 to 450 nm in the<unk>  spectrum, which has a number of<unk>  effects, including those on the eye. Despite a lack of any concurring scientific evidence, HEV<unk>  has sometimes been claimed to be a cause of age-related macular degeneration. Some sunglasses and beauty creams specifically block HEV, for added marketing value. Currently, a 2019 report by France's Agency for Food, Environmental and Occupational Health & Safety (ANSES) supports the 2010 result on the adverse effect of blue LED<unk>  (400-450 nm spike) on the eye, which can lead to impaired vision. It<unk><unk> s short-term effects on the retina linked to intense exposure to blue LED<unk> , and long-term effects linked to the onset of age-related macular degeneration. Harvard Health Publishing additionally asserts that exposure to blue<unk>  (especially blue LED<unk> , but also broad-spectrum blue<unk>  at<unk>  has a stronger negative effect on sleep. A June 14, 2016 press release by the American Medical Association concludes that there are negative health impacts from the unrestrained use of LED street<unk> ing in general.
Biological effects of high-energy visible light
Physiological effects in space
Photosensitive drug reaction
Electrochemical skin conductance
Drug delivery to the brain
Human skin color
Neurobiological effects of physical exercise
Repetitive visual stimulus