In biomedical research,<unk>  is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores.<unk>  is an allosteric blocker of channel function. At low concentrations,<unk>  causes an initial inhibition of spontaneous calcium release events, while at high concentrations,<unk>  blocks release completely.
Tetracaine
Procaine
Articaine
Bupivacaine
Iontocaine
Ibogaine
Levobupivacaine
Proxymetacaine