<unk>  is contraindicated in patients with: * Psychiatric conditions as bulimia nervosa, anorexia nervosa, serious depression or pre-existing mania * Patients with a history of or a predisposition to drug or alcohol abuse * Hypersensitivity to the drug or any of the inactive ingredients * Patients below 18 and above 65 years of age * Concomitant treatment with a MAO inhibitor, antidepressant or other centrally active drugs, particularly other anoretics * History of peripheral arterial disease * Hypertension that is not sufficiently controlled (e.g., >145/90 mmHg), caution in controlled hypertension * Existing pulmonary hypertension * Existing damage on heart valves, coronary heart disease, congestive heart failure, serious arrhythmias, previous myocardial infarction * A history of coronary artery disease (e.g., angina, history of myocardial infarction), congestive heart failure, tachycardia, peripheral arterial occlusive disease, arrhythmia or cerebrovascular disease (stroke or transient ischemic attack (TIA)) * Stroke or transient ischemic attack (TIA) * Hyperthyroidism (overactive thyroid gland) * Closed angle glaucoma * Seizure disorders * Enlargement of the prostate gland with urinary retention (relative contraindication) * Pheochromocytoma * Pregnant and lactating women (relative contraindication)
Sibutramine
Lofepramine
Quinupramine
Mitapivat
Metapramine
Nyasol
Tasimelteon
Pipotiazine