* In patients with known allergy to the cephalosporin class of antibiotics or any of its components. * Patients with carnitine deficiency or inborn errors of metabolism that may result in clinically significant carnitine deficiency, because use of<unk>  causes renal excretion of carnitine. Safety and tolerability == *<unk>  pivoxil is generally well-tolerated, with most adverse events being of mild-to-moderate severity and self-limiting. Gastrointestinal adverse events (e.g., diarrhoea, nausea and abdominal pain) were the most commonly reported adverse events, although they seldom led to treatment discontinuation. * In a post-marketing surveillance evaluating safety in 2006 children with acute otitis media treated with<unk>  (median daily dose: 10.0 mg/kg with a median total treatment period of 7 days), the incidence of adverse reactions was 1.79%, without unexpected or serious adverse drug reactions reported. The most frequent adverse drug reaction was diarrhea (1.30%) that resolved or subsided during treatment or after discontinuation or completion of therapy in all cases. * Data from the clinical studies carried out with<unk>  in the treatment of pharyngotonsillitis from 2007 to 2010 in Japan showed that the percentage of adverse events was very low and diarrhea was the most frequent event. In the largest study (734 children), the incidence of adverse reactions was 1.50% (11 events in 11 patients), with 3 events of diarrhea and three of hematuria in urinalysis without clinical symptoms. In a study carried out in children in Thailand comparing<unk>  (66 patients) with amoxicillin/clavulanic acid (72 patients) for 10 days in the treatment of acute bacterial rhinosinusitis, the most frequent adverse event was diarrhea, with significant (P = 0.02) differences in the percentages found for both compounds (4.5% with<unk>  vs. 18.1% for amoxicillin/clavulanic acid).
Cefditoren
Meropenem
Cefepime
Imipenem
Aztreonam
Ertapenem
Cefotaxime
Levofloxacin