In<unk>  there is a diffuse multifocal cortical hyperexcitability, which is age (maturation)-related. This diffuse epileptogenicity may be unequally distributed, predominating in one area, which is often posterior. Epileptic discharges in<unk> , irrespective of their location at onset, activate emetic and autonomic centers prior to any other conventional neocortical seizure manifestations. An explanation for this is that children are susceptible to autonomic disorders as illustrated by the cyclic vomiting syndrome, which is a nonepileptic condition specific to childhood.<unk>  and all other benign childhood focal seizures, with rolandic epilepsy as their main representative, are probably linked due to a common, genetically-determined, mild, and reversible functional derangement of the brain cortical maturational process that<unk>  proposed as "benign childhood seizure susceptibility syndrome". The various EEG and seizure manifestations often follow an age- (maturation-) related localization.<unk>  is probably the early onset phenotype of the benign childhood seizure susceptibility syndrome. During a recorded autonomic seizure, there was a small increase in blood pressure (+5/4 mm Hg, systolic/diastolic), pronounced increases in heart rate (+59 bpm) and plasma concentrations of norepinephrine (+242 pg/mL), epinephrine (+175 pg/mL), and vasopressin (+22.1 pg/mL); serum glucose was also elevated (206 mg/dL). The significant increase in plasma vas#pressin may explain the emetic autonomic symptoms.
Panayiotopoulos syndrome
Fryns-Aftimos syndrome
Sotos syndrome
Cortes Lacassie syndrome
Patau syndrome
Lelis syndrome
Berk–Tabatznik syndrome
Tangier disease