The skin manifestations of recluse venom are thought to arise from Sphingomyelinase D. The enzyme acts on cell membranes. The action is therefore limited as the venom can only spread through a set area. The originally red swollen area becomes a dry black ulcer. Skin infections, in particular the widespread methicillin-resistant Staphylococcal aureus, remain swollen and red. Pus forms and the lesion often drains. It can continue to spread and expand as the bacteria grow. Other skin lesions and infections are much more common than<unk><unk> . Physicians have reported brown recluse<unk><unk>  where no brown recluse exist. Ed: in 100 pictures retrieved online only 3 were consistent with Sphingomyelinase<unk> .
Pathophysiology of spider bites
Hypoalgesic effect of swearing
Genetics of synesthesia
Inflammatory reflex
Cutaneous perforating disorders
Pain in animals
Allergic reactions to anesthesia
Recurrent painful ophthalmoplegic neuropathy