Biotransformation is mainly hepatic, with approximately 30-40% metabolized to inactive metabolites. Protein Binding ranges from 60 to 80%.<unk>  is rapidly absorbed after oral administration. The presence of food delays absorption but does not affect total absorption. The mean serum half-life is 1.5 hours. Half-life in patients with impaired renal function may exceed 10 hours.
Cinoxacin
Azithromycin
Roxithromycin
Levofloxacin
Telithromycin
Dirithromycin
Pefloxacin
Gemifloxacin