<unk>  causes many issues with an individual’s connective tissues. Some general characteristics of an individual with<unk>  include bone flexibility and deformities, short stature, delayed acquisition of speech and motor skills, dolichocephalic skull, Wormian bone, small maxilla, hypoplastic frontal sinuses, basilar impression, joint laxity, bulbous finger tips and severe osteoporosis. Wormian bone occurs when extra bones appear between cranial sutures. Fetuses with<unk>  often will not be seen to unclench their hands on obstetrical ultrasound. They may also have low-set ears and their eyes may be farther apart than on a usual child, called hypertelorism. Children's heads can have some deformities in their shape and size (plagiocephaly). Early tooth loss and bone deformities, such as serpentine tibiae and fibulae, are also common in those affected.
Hajdu–Cheney syndrome
Cleidocranial dysostosis
MEDNIK syndrome
ATR-16 syndrome
Aarskog–Scott syndrome
Treacher Collins syndrome
GRACILE syndrome
Heimler syndrome