<unk> sis in a patient with abetalipoproteinemia<unk> s arise from either alterations in membrane lipids or structural proteins. Alterations in membrane lipids are seen in abetalipoproteinemia and liver dysfunction. Alteration in membrane structural proteins are seen in neuroacanthocytosis and McLeod syndrome. In liver dysfunction, apolipoprotein A-II deficient lipoprotein accumulates in plasma causing increased cholesterol in RBCs. This causes abnormalities of membrane of RBC causing remodeling in spleen and formation of<unk> s. In abetalipoproteinemia, there is deficiency of lipids and vitamin E causing abnormal morphology of RBCs.
Acanthocyte
Echinocyte
Centrocyte
Koilocyte
Podocyte
Agranulocyte
Elliptocyte
Melanocyte