<unk> , also known as<unk> ,<unk> -acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and mediator of many leukocyte functions,<unk>  aggregation and degranulation, inflammation, and anaphylaxis. It is also involved in changes to vascular permeability, the oxidative burst, chemotaxis of leukocytes, as well as augmentation of arachidonic acid metabolism in phagocytes.<unk>  is produced by a variety of cells, but especially those involved in host defense, such as<unk> s, endothelial cells, neutrophils, monocytes, and macrophages.<unk>  is continuously produced by these cells but in low quantities and production is controlled by the activity of<unk>  acetylhydrolases. It is produced in larger quantities by inflammatory cells in response to specific stimuli.
Platelet-activating factor
Thrombin
Von Willebrand factor
Prothrombinase
Factor VIII 
Factor VIII
Kallikrein
Fibrinogen