<unk>  <unk>  is a rare complication of blood transfusion, in which the immunologically competent donor T lymphocytes mount an immune response against the recipient's lymphoid tissue. These donor lymphocytes engraft, recognize recipient cells as foreign and mount an immune response against recipient tissues. Donor lymphocytes are usually identified as foreign and destroyed by the recipient's immune system. However, in situations where the recipient is severely immunocompromised, or when the donor and recipient HLA type is similar (as can occur in directed donations from first-degree relatives), the recipient's immune system is not able to destroy the donor lymphocytes. This can result in<unk> .
Transfusion-associated graft-versus-host disease
Transfusion-related acute lung injury
Transfusion associated circulatory overload
Transfusion-related immunomodulation
Transfusion transmitted infection
Post-transplant lymphoproliferative disorder
Immune reconstitution inflammatory syndrome
Overwhelming post-splenectomy infection