The most common cause (80%) is acute viral pharyngitis, a viral infection of the throat. Other causes include other bacterial infections (such as group A streptococcus or streptococcal pharyngitis), trauma, and tumors. Gastroesophageal (acid) reflux disease can cause stomach acid to back up into the throat and also cause the throat to become sore. In children, streptococcal pharyngitis is the cause of 35–37% of sore throats. The<unk>  of a viral infection and a bacterial infection may be very similar. Some clinical guidelines suggest that the cause of a sore throat is confirmed prior to prescribing antibiotic therapy and only recommend antibiotics for children who are at high risk of non-suppurative complications. A group A streptococcus infection can be diagnosed by throat culture or a rapid test. In order to perform a throat culture, a sample from the throat (obtained by swabbing) is cultured (grown) on a blood agar plate to confirm the presence of group A streptococcus. Throat cultures are effective for people who have a low bacterial count (high sensitivity), however, throat cultures usually take about 48 hours to obtain the results. Clinicians often also make treatment decisions based on the person's signs and<unk>  alone. In the US, approximately 2/3rd of adults and half of children with sore throat are diagnosed based on<unk>  and do not have testing for the presence of GAS to confirm a bacterial infection. Rapid tests to detect GAS (bacteria) give a positive or negative result that is usually based on a colour change on a test strip that contains a throat swab (sample). Test strips detect a cell wall carbohydrate that is specific to GAS by using an immunologic reaction. Rapid testing can be performed in the doctors office and usually takes 5–10 minutes for the test strip to indicate the result. Specificity for most rapid tests is approximately 95%, however sensitivity is about 85%. Although the use of rapid testing has been linked with an overall reduction in antibiotic prescriptions, further research is necessary to understand other outcomes such as safety, and when the person starts to feel better. Numerous clinical scoring systems (decision tools) have also been developed to support clinical decisions. Scoring systems that have been proposed include Centor's, McIsaac's, and the feverPAIN. A clinical scoring system is often used along with a rapid test. The scoring systems use observed signs and<unk>  in order to determine the likelihood of a bacterial infection.
symptoms of Common cold
symptom of Common cold
symptom of Tularemia
symptom of Listeriosis
symptom of Influenza
symptom of Measles
symptoms of Tularemia
symptom of Croup