The most common causes of<unk>  in developed countries are infectious mononucleosis, splenic infiltration with cancer cells from a hematological malignancy and portal hypertension (most commonly secondary to liver disease, and sarcoidosis).<unk>  may also come from bacterial infections, such as syphilis or an infection of the heart's inner lining (endocarditis).<unk>  also occurs in mammals parasitized by Cuterebra fontinella. The possible causes of moderate<unk>  (spleen 1000 g) are * chronic myelogenous leukemia * myelofibrosis * malaria * splenic marginal zone lymphoma
Splenomegaly
Hepatosplenomegaly
Lycopenemia
Lymphocytosis
Lymphocytopenia
Plasmacytosis
Neutrophilia
Reticulocytosis