Due to the rarity of this disease, there is a lack of comprehensive and high quality research about the different treatment options, and therefore, no specific treatment plan is followed globally. However, some studies have attempted to outline the most widely accepted approaches in dealing with<unk> . Fluorinated steroids There is no agreement on using fluorinated steroids in treating<unk> , and the results of the different studies are contradictory. These steroids (such as dexamethasone) are used when the disease is diagnosed in utero as they can cross the placenta without being deactivated. The main goal of using corticosteroids is to mitigate the inflammation by decreasing the amount of anti Ro/La autoantibodies in the fetal serum. Therefore, they are used in the autoimmune-mediated<unk> . Both the mother and the fetus might suffer from their side effects which can include growth problems and adrenal insufficiency. Beta-adrenergic agonist Trebutaline and Sulbutamol are among the medications that have been used to treat<unk> . They are used mainly to increase the heart rate in fetuses suffering from bradycardia. Although they showed positive results, some patients showed intolerance to their side effects. Plasmapheresis Plasma exchange in women positive to anti Ro/La autoantibodies has not been studied thoroughly, but it is suggested to have and effect on the titer of the antibodies in the mother's serum and therefore might have a preventive role. Intravenous immunoglobulin Using intravenous immunoglobulin showed some promising results in decreasing the possibility of having<unk> 's complications such as EFE and cardiomyopathy. Hydroxychloroquine Hydroxychloroquine is relatively new approach, but it showed promising results in preventing the inflammation and other injuries result from it such as fibrosis. Apart from these medications, a pace maker might be needed in around two thirds of the cases, and a procedure might be required when the heart has structural abnormalities.
Congenital heart block
Ectopic pacemaker
Cyanotic heart defect
Acyanotic heart defect
Cardiac myxoma
Heart valve dysplasia
Primary tumors of the heart
Broken Heart