Three measures of global<unk>  mortality from 1990 to 2017 Survival rates vary by<unk>  type and by the stage at which it is diagnosed, ranging from majority survival to complete mortality five years after diagnosis. Once a<unk>  has metastasized, prognosis normally becomes much worse. About half of patients receiving treatment for invasive<unk>  (excluding<unk> rcinoma in situ and non-melanoma skin<unk> s) die from that<unk>  or its treatment. A majority of<unk>  deaths are due to metastases of the primary tumor. Survival is worse in the developing world, partly because the types of<unk>  that are most common there are harder to treat than those associated with developed countries. Those who survive<unk>  develop a second primary<unk>  at about twice the rate of those never diagnosed. The increased risk is believed to be due to the random chance of developing any<unk> , the likelihood of surviving the first<unk> , the same risk factors that produced the first<unk> , unwanted side effects of treating the first<unk>  (particularly radiation therapy), and better compliance with screening. Predicting short- or long-term survival depends on many factors. The most important are the<unk>  type and the patient's age and overall health. Those who are frail with other health problems have lower survival rates than otherwise healthy people. Centenarians are unlikely to survive for five years even if treatment is successful. People who report a higher quality of life tend to survive longer. People with lower quality of life may be affected by depression and other complications and/or disease progression that both impairs quality and quantity of life. Additionally, patients with worse prognoses may be depressed or report poorer quality of life because they perceive that their condition is likely to be fatal. People with<unk>  have an increased risk of blood clots in their veins which<unk> n be life-threatening. The use of blood thinners such as heparin decrease the risk of blood clots but have not been shown to increase survival in people with<unk> . People who take blood thinners also have an increased risk of bleeding. Although extremely rare, some forms of<unk> , even from an advanced stage,<unk> n heal spontaneously. This phenomenon is known as the spontaneous remission.
Cancer
Anorexia nervosa
Disease
Heartburn
Cardiovascular disease
Vaginitis
Skin cancer
Neuropathic pain