The most common (roughly 1%) side effect of<unk>  is joint pains (arthralgia), but this is not usually so severe that patients need to stop taking it.<unk>  can precipitate gout flares by decreasing renal excretion of uric acid. The most dangerous side effect of<unk>  is hepatotoxicity, which is dose-related. The old dose for<unk>  was 40–70 mg/kg daily and the incidence of drug-induced hepatitis has fallen significantly since the recommended dose has been reduced to 12–30 mg/kg daily. In the standard four-drug regimen (isoniazid, rifampicin,<unk> , ethambutol),<unk>  is the most common cause of drug-induced hepatitis. It is not possible to clinically distinguish<unk> -induced hepatitis from hepatitis caused by isoniazid or rifampicin; test dosing is required (this is discussed in detail in tuberculosis treatment) Other side effects include nausea and vomiting, anorexia, sideroblastic anemia, skin rash, urticaria, pruritus, dysuria, interstitial nephritis, malaise, rarely porphyria, and fever.
Pyrazinamide
Safinamide
Ethambutol
Isoniazid
Oxepanoprolinamide
Rifampicin
Rifampicin/isoniazid/pyrazinamide
Rifabutin