Use of<unk>  should be avoided, when possible, in individuals with these conditions: * Ataxia (gross lack of coordination of muscle movements) * Severe hypoventilation * Acute narrow-angle glaucoma * Severe hepatic deficiencies (hepatitis and liver cirrhosis decrease elimination by a factor of two) * Severe renal deficiencies (e.g. patients on dialysis) * Sleep apnea * Severe depression, particularly when accompanied by suicidal tendencies * Acute intoxication with alcohol, narcotics, or other psychoactive substances * Myasthenia gravis (autoimmune disorder causing muscle weakness) * Hypersensitivity or allergy to any drug in the benzodiazepine class Special caution needed<unk>  should not be used in pregnancy, as it may cause harm to the fetus. The safety and effectiveness of<unk>  has not been established in children; therefore,<unk>  should generally not be given to individuals under 18 years of age, and should not be used at all in children under six months old. Benzodiazepines also require special caution if used in the elderly, alcohol- or drug-dependent individuals, and individuals with comorbid psychiatric disorders.<unk> , similar to other benzodiazepines and nonbenzodiazepine hypnotic drugs, causes impairments in body balance and standing steadiness in individuals who wake up at night or the next morning. Falls and hip fractures are frequently reported. The combination with alcohol increases these impairments. Partial but incomplete tolerance develops to these impairments. The smallest possible effective dose should be used in elderly or very ill patients, as a risk of apnea and/or cardiac arrest exists. This risk is increased when<unk>  is given concomitantly with other drugs that depress the central nervous system (CNS). Misuse and dependence Because benzodiazepines can be abused and lead to dependence, their use should be avoided in people in certain particularly high-risk groups. These groups include people with a history of alcohol or drug dependence, people significantly struggling with their mood or people with longstanding mental health difficulties. If<unk>  must be prescribed to people in these groups, they should generally be monitored very closely for signs of misuse and development of dependence.
Temazepam
Oxazepam
Medazepam
Diclazepam
Halazepam
Camazepam
Cinolazepam
Quazepam