<unk>  is a typical non-depolarizing curare-mimetic muscle relaxant. It competitively inhibits the nicotinic acetylcholine receptor at the neuromuscular junction by blocking the binding of acetylcholine. It has slight vagolytic activity, causing an increase in heart rate, but no ganglioplegic (i.e., blocking ganglions) activity. It is a very potent muscle relaxant drug, with an ED95 (i.e., the dose that causes 95% depression of muscle twitch response) of only 60 µg/kg body weight. Onset of action is relatively slow compared to other similar drugs, in part due to its low dose: an intubating dose takes 3–6 minutes for full effect. Clinical effects (muscle activity lower than 25% of physiological) last for about 100 minutes. The time needed for full (over 90% muscle activity) recovery after single administration is about 120–180 minutes in healthy adults. The effects of<unk>  can be at least partially reversed by anticholinesterasics, such as neostigmine, pyridostigmine, and edrophonium.
Pancuronium bromide
Rocuronium bromide
Rapacuronium bromide
Vecuronium bromide
Alcuronium chloride
Suxamethonium chloride
Gantacurium chloride
Mivacurium chloride