Adverse effects by incidence: Very common (>10% incidence) adverse effects include: * Anorexia * Somnolence * Dizziness * Agitation * Irritability * Confusional state * Depression * Diplopia * Memory impairment * Decreased bicarbonate Common (1-10% incidence) adverse effects include: * Ecchymosis * Hypersensitivity * Affect lability * Anxiety * Insomnia * Psychotic disorder * Bradyphrenia * Disturbance in attention * Nystagmus * Paraesthesia * Speech disorder * Tremor * Abdominal pain * Constipation * Diarrhoea * Dyspepsia * Nausea * Rash * Pruritus * Alopecia * Nephrolithiasis * Fatigue * Influenza-like illness * Pyrexia * Oedema peripheral * Weight loss Interactions<unk>  and other carbonic anhydrase inhibitors such as topiramate, furosemide, and hydrochlorothiazide have been known to interfere with amobarbital, which has led to inadequate anesthetization during the Wada test.<unk>  may also interact with other carbonic anhydrase inhibitors to increase the potential for metabolic acidosis. Additionally, the metabolism of<unk>  is inhibited by ketoconazole, ciclosporin, miconazole, fluconazole and carbamazepine (in descending order of inhibition) due to their effects on the CYP3A4 enzyme.<unk>  is not known to inhibit cytochrome P450 enzymes when present at therapeutic concentrations.
Zonisamide
Galantamine
Mesuximide
Ethosuximide
Phenytoin
Propazepine
Levetiracetam
Carbamazepine