Patients with<unk>  present with a combination of chronic, nonspecific GI symptoms, including abdominal pain, bloating, early satiety, abdominal cramping, diarrhea, nausea, and vomiting 1, 2, 9, 10, 18, 19.<unk>  symptoms are often indistinguishable from those of functional GI disorders such as irritable bowel syndrome or functional dyspepsia, which can result in delayed diagnoses, misdiagnoses, and improper treatment 20-22. Longer duration of GI symptoms has been correlated with probability of<unk> 23. The endoscopic features of the GI mucosa are varied and nonspecific in patients with<unk> —many patients have no or mild endoscopic abnormalities, such as erythema 15, 18, making it a challenge to detect 23, 24. Collection of gastrointestinal biopsies and histologic analysis, with counting of eosinophils, is required for diagnosis of<unk>  19. The variations in clinical presentation, subtle or nonexistent endoscopic abnormalities, involvement of several GI segments, requirement for collection of multiple biopsies, and patchiness of<unk>  infiltration contribute to underdiagnosis of<unk> 14, 25. Some but not all patients with<unk>  have increased serum levels of IgE, peripheral eosinophils, or α2-macroglobulin 12, 13, 18, 19, 26, 27. The Consortium of<unk>  Gastrointestinal Disease Researchers (CEGIR) aims to quantify endoscopic, molecular, and histologic findings in patients with<unk>  3.
Eosinophilic gastroenteritis
Travelers' diarrhea
Rotaviral gastroenteritis
Cytomegalovirus colitis
Intestinal spirochetosis
Antibiotic-associated diarrhea
Giardiasis
Intestinal capillariasis