<unk>  (arrow) is present in this brain after a stroke (infarct depicted in shaded area).<unk>  is a<unk>  of the brain past its center line. The sign may be evident on neuroimaging such as CT scanning. The sign is considered ominous because it is commonly associated with a distortion of the brain stem that can cause serious dysfunction evidenced by abnormal posturing and failure of the pupils to constrict in response to light.<unk>  is often associated with high intracranial pressure (ICP), which can be deadly. In fact,<unk>  is a measure of ICP; presence of the former is an indication of the latter. Presence of<unk>  is an indication for neurosurgeons to take measures to monitor and control ICP. Immediate surgery may be indicated when there is a<unk>  of over 5 mm. The sign can be caused by conditions including traumatic brain injury, stroke, hematoma, or birth deformity that leads to a raised intracranial pressure.
Midline shift
Left shift 
Hyperintensity
Hyperfocus
Flattening the curve
Endaural phenomena
Intrinsicoid deflection
Transmarginal inhibition