Most cases of this condition tend to be recalcitrant to treatment, with topical and oral antibiotic regimens commonly used for<unk>  generally being ineffective. For the severe forms of this disease, oral isotretinoin therapy has been used, and the condition responds well to doses of 0.5 to 1 mg/kg/day. However, unlike in the treatment of acne vulgaris, lasting responses to isotretinoin generally do not occur, and long-term maintenance therapy with oral tetracyclines is usually necessary. Eyelid reduction surgery has also been reported to help with the cosmetic appearance of the condition, but does not alter the disease progression.
Persistent edema of rosacea
Recurrent corneal erosion
Recurrent painful ophthalmoplegic neuropathy
Localized heat contact urticaria
Dichoptic presentation
Aquagenic pruritus
Non scarring hair loss
Atypical facial pain