<unk>  interacts with the antibiotic erythromycin, a strong inhibitor of CYP3A4, which affects concentration peak time. Alone, this interaction is not believed to be clinically important. However, anxiety, tremor, and depression were documented in a case report involving a patient undergoing treatment for acute pneumonia and renal failure. Following administration of<unk> , triazolam, and subsequently erythromycin, the patient experienced repetitive hallucinations and abnormal bodily sensations. Coadministration of benzodiazepine drugs at therapeutic doses with erythromycin may cause serious psychotic symptoms, especially in persons with other, significant physical complications. Oral contraceptive pills reduce the clearance of<unk> , which may lead to increased plasma levels of<unk>  and accumulation. Rifampin significantly increases the clearance of<unk> , while probenecid significantly decreases its clearance. Cimetidine slows down the elimination rate of<unk> , leading to more prolonged effects and increased risk of accumulation. Alcohol in combination with<unk>  may cause a synergistic enhancement of the hypotensive properties of both benzodiazepines and alcohol. Benzodiazepines including<unk>  may inhibit the glucuronidation of morphine, leading to increased levels and prolongation of the effects of morphine in rat experiments.
Nitrazepam
Avacopan
Atogepant
Bupranolol
Beclamide
Clonidine
Brimonidine
Tofisopam