<unk>  is believed to be caused by a combination of genetic and environmental factors. After having one child with the condition, or if a parent has the condition, there is a 4% chance the next child will also be affected. A folic acid deficiency during pregnancy also plays a significant role. Other risk factors include certain antiseizure medications, obesity, and poorly managed diabetes. Alcohol misuse can trigger macrocytosis which discards folate. After stopping the drinking of alcohol, a time period of months is needed to rejuvenate bone marrow and recover from the macrocytosis. Those who are white or Hispanic have a higher risk. Girls are more prone to being born with<unk> .
Spina bifida
Teratoma
Hydranencephaly
Anencephaly
Lissencephaly
Exencephaly
Schizencephaly
Cranioschisis