In the developed world<unk>  is a rare complication of pregnancy, usually manifesting after excessive blood loss after delivery. The presence of disseminated intravascular coagulation (i.e., in amniotic fluid embolism or HELLP syndrome) also appears to be a factor in its development. A retrospective study in Turkey found that the prevalence of<unk>  was directly proportional to the amount of at-home deliveries each decade. This may be due to previously limited obstetric techniques present in a home environment. For example, an area of improvement in preventing the condition could be an increase in the efficacy of treatment to hypovolemic shock through blood transfusion. Pituitary necrosis may directly result from a lack of blood flow in the hypophyseal artery as a result of pituitary gland enlargement during pregnancy. One cause of pituitary growth associated with the risk of<unk>  is the hyperplasia of lactotrophs (responsible for prolactin production). Ischemia may occur as a result of vasospasm, thrombosis, or vascular compression sometimes as a result of an increase in the amount of lactotroph cells throughout gestation (contributing to the enlargement of the pituitary gland). Necrosis may occur as a result of severe hypotension or shock due to excessive uterine bleeding following childbirth.<unk>  may occur as a result of the arterial constriction and abnormal hypotension in conjunction with an insufficiency to meet the increased demand in blood supply of the pituitary gland seen during pregnancy. This increased blood-flow and metabolic demand is associated with the previously mentioned hyperplasia of lactotrophs. Some possible predisposing factors to<unk>  may include: inherited or acquired disseminated blood coagulation (DIC), restriction pituitary blood supply, small sella size, vasospasm, or thrombosis. Post-Partum Hemorrhaging (PPH) is believed to be a predictor of<unk> , so the symptoms of anaemia, obesity, and advanced maternal age may increase the risk of<unk>  Syndrome. Atony of the uterus may be related to PPH that could induce<unk> . This results in the abnormally prolonged flow of blood to the placenta after delivery.
Sheehan's syndrome
Young's syndrome
Addison's disease
complications of Graves' disease
Hyperprolactinemic SAHA syndrome
complications of Acromegaly
complications of Hashimoto's thyroiditis
Young–Madders syndrome