<unk>  occurrence is limited to 13 provinces and two autonomous regions of China. It has also been reported in Siberia and North Korea, but incidence in these regions is reported to have decreased with socio-economic development. In China, KBD is estimated to affect some 2 million to 3 million people across China, and 30 million are living in endemic areas. Life expectancy in KBD regions has been reported to be significantly decreased in relation to selenium deficiency and Keshan<unk>  (endemic juvenile dilative cardiomyopathia). The prevalence of KBD in Tibet varies strongly from valley to valley, and village to village. Prevalence of clinical symptoms suggestive of KBD reaches 100% in 5- to 15-year-old children in at least one village. Prevalence rates of over 50% are not uncommon. A clinical prevalence survey carried out in Lhasa prefecture yielded a figure of 11.4% for a study population of approximately 50,000 inhabitants. As in other regions of China, farmers are by far the most affected population group.
Kashin–Beck disease
Kufor–Rakeb syndrome
Mowat–Wilson syndrome
Zunich–Kaye syndrome
Qazi–Markouizos syndrome
Wilson–Mikity syndrome
Gerstmann–Sträussler–Scheinker syndrome
Scheie syndrome