Prognosis is poor. One sixth of reported cases died during childhood, usually the result of status epilepticus and/or respiratory insufficiency. Nearly all children develop severe intellectual disability. Children generally are unable to use language. Some children can walk and grasp objects. Children may be able to continue to develop normally during seizure-free periods, but they typically rapidly deteriorate when "stormy periods" recur. However, some cases of only mild to moderate mental delay have been reported in the context of good seizure control. Those with better outcomes seem to have been borderline cases to begin with, as in the seizures were not as long-lasting and less migratory.
Malignant migrating partial seizures in infancy
Childhood absence epilepsy
Benign familial neonatal seizures
Benign infantile epilepsy
Benign familial infantile epilepsy
Autosomal dominant nocturnal frontal lobe epilepsy
Generalized epilepsy with febrile seizures plus
Benign neonatal seizures