The pathophysiology of<unk>  is unclear. Some scientists believe that it may be a variation of prurigo nodularis. The theory that most scientists agree upon is that<unk>  is an elimination of keratin and other cellular material across the epidermis. Keratinization in<unk>  form at the basilar layer that is lower than the normal proliferation region in the epidermis. This causes an inflammatory response which results with the keratin, along with other cellular material and connective tissue, to be forced out the epidermis. Another reason for an inflammatory response may be due to an alteration of the dermal connective tissue. This is theorized because this step is a main reason for inflammatory responses in other skin<unk> s, such as, elastosis perforans serpiginosa and perforating collagenosis.
Kyrle disease
Haff disease
Degos disease
Salla disease
Camisa disease
Bayoud disease
Borna disease
Pott disease