General<unk>  is of low toxicity. Its metabolite malaoxon is 61x more toxic, being a more potent inhibitor of acetylcholinesterase. According to the United States Environmental Protection Agency, no reliable information is available on adverse health effects of chronic exposure. In 1981, B. T. Collins, director of the California Conservation Corps, publicly swallowed a mouthful of dilute<unk>  solution to demonstrate its safety following an outbreak of Mediterranean fruit flies in California.<unk>  was sprayed over a area to control the flies. Carcinogenicity<unk>  is classified by the IARC as probable carcinogen (group 2A).<unk>  is classified by US EPA as having "suggestive evidence of carcinogenicity". This classification was based on the occurrence of liver tumors at excessive doses in mice and female rats and the presence of rare oral and nasal tumors in rats that occurred following exposure to very large doses. Exposure to organophosphates is associated with non-Hodgkin's lymphoma.<unk>  used as a fumigant was not associated with increased cancer risk. Between 1993 and 1997, as part of the Agricultural Health Study, no clear association between<unk>  exposure and cancer was reported. Amphibians<unk>  is toxic to leopard frog tadpoles.
Malathion
Parathion
Chlorpyrifos
Dotinurad
Ajmalicine
Diisopropyl fluorophosphate
Pirimiphos-methyl
Carbaryl