* Infection: Stomach acid plays a role in killing ingested bacteria. Use of<unk>  may increase the chance of developing infections such as pneumonia, particularly in hospitalized patients. Common * Gastrointestinal: abdominal pain (6%), diarrhea (9%), flatulence (4%), nausea (7%), vomiting (4%) * Neurologic: headache (12%), dizziness (3%) * Neuromuscular and skeletal: arthralgia (3%) Rare * Gastrointestinal: constipation, dry mouth, hepatitis * Blood problems: low white blood cell count, thrombocytopenia * Immunologic: Stevens–Johnson syndrome, toxic epidermal necrolysis * Metabolic: elevated creatine kinase, elevated cholesterol levels, elevated liver enzymes (AST/ALT), swelling * Musculoskeletal: Muscle disorders, bone fracture and infection, Clostridium difficile infection, osteoporosis-related hip fracture, rhabdomyolysis * Kidneys: interstitial nephritis * Nutrition: may reduce the absorption of important nutrients, vitamins, and minerals, including certain medications, leaving users at increased risk for pneumonia. Long-term use * Osteoporosis and bone fracture have been observed in people on high-dose and/or long-term (over one year) prescription proton pump inhibitors. * Hypomagnesia has been observed in people on medications like<unk>  when taken for longer periods of time (generally one year or more, although cases have been reported with regimens as short as three months). Discontinuation In people taking PPIs for longer than six months, a dose taper should be considered prior to discontinuation. For those on a moderate to high dose, this can be done by 50 percent every week until on the lowest dose. After a week it can then be stopped.
Pantoprazole
Lansoprazole
Dexlansoprazole
Tenatoprazole
Rabeprazole
Omeprazole
Esomeprazole
Ranitidine