In a study in British Columbia, the overall incidence of the<unk>  were estimated to be 40 per 100,000 live births or 1 in 2,500 births, overall representing more than approximately 15% of single gene disorders in the population. While a Mexican study established an overall incidence of 3.4: 1000 live newborns and a carrier detection of 6.8:1000 NBS. Type of<unk>  error Incidence Disease involving amino acids (e.g. PKU), organic acids, primary lactic acidosis, galactosemia, or a urea cycle disease 24 per 100 000 births 1 in 4,200 Lysosomal storage disease 8 per 100 000 births 1 in 12,500 Peroxisomal disorder ~3 to 4 per 100 000 of births ~1 in 30,000 Respiratory chain-based mitochondrial disease ~3 per 100 000 births 1 in 33,000 Glycogen storage disease 2.3 per 100 000 births 1 in 43,000
Inborn errors of metabolism
Inborn errors of carbohydrate metabolism
Sphingolipidoses
Mitochondrial disease
GM1 gangliosidoses
Neonatal hemochromatosis
GM2 gangliosidoses
Congenital disorders of amino acid metabolism