Symptoms vary from person to person, and may come and go. Almost everyone with lupus has joint pain and swelling. Some develop arthritis. Frequently affected joints are the fingers, hands, wrists, and knees. Other common symptoms include: * chest pain during respiration * joint pain (stiffness and swelling) * painless oral ulcer * fatigue * weight loss * headaches * fever with no other cause * Skin<unk> sions that appear worse after sun exposure * general discomfort, uneasiness, or ill feeling (malaise) * hair loss * sensitivity to sunlight * a "butterfly" facial rash, seen in about half of people with SLE * swollen lymph nodes Photosensitivity Photosensitivity is the amount to which an object reacts upon receiving photons especially in visible light. Photosensitivity is a known symptom of lupus, but its relationship to and influence on other aspects of the disease remain to be defined. Causes of photosensitivity may include: * change in autoantibody location * cytotoxicity * induction of apoptosis with autoantigens in apoptotic blebs * upregulation of adhesion molecules and cytokines * induction of nitric oxide synthase expression * ultraviolet-generated antigenic DNA
Lupus erythematosus
Tumid lupus erythematosus
Discoid lupus erythematosus
Chilblain lupus erythematosus
Rheumatism
Polymyalgia rheumatica
Scleroderma
Drug-induced lupus erythematosus