<unk> " ( 'only<unk> ') is an adage intended to indicate a basic principle of toxicology. It is credited to Paracelsus who expressed the classic toxicology maxim "All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison." This is often condensed to:<unk> " or in Latin, . It means that a substance can produce the harmful effect associated with its toxic properties only if it reaches a susceptible biological system within the body in a high enough concentration (i.e.,<unk> . The principle relies on the finding that all chemicals—even water and oxygen—can be toxic if too much is eaten, drunk, or absorbed. "The toxicity of any particular chemical depends on many factors, including the extent to which it enters an individual’s body." This finding also provides the basis for public health standards, which specify maximum acceptable concentrations of various contaminants in food, public drinking water, and the environment. However, there is no linear relationship and chemical toxicity is more complex than merely the acute effects caused by short-term exposure. Relatively low<unk> s of contaminants in water, food, and environment can already have significant chronic effects if there is long-term exposure. Generally the effects of different<unk> s can be very different at different levels (not only bigger and smaller impacts depending on<unk> .
The dose makes the poison
The Dose Makes the Poison
Water for injection
Toxic capacity
Virtually safe dose
Paracetamol brand names
Pain in animals
Measured environmental concentration