The first line of therapy after diagnosis typically involves the administration of the combined oral contraceptive pill, medroxyprogesterone acetate or a gonadotropin-releasing hormone agonist to suppress menstruation and thereby relieve pain. Surgically,<unk>  has historically been treated through hysterectomy (removal of the uterus) to relieve symptoms caused by hematocolpos (the accumulation of menstrual fluid in the vagina). Other surgical methods of management involve the creation of an anastomotic connection between the uterus and vagina by neovaginoplasty or recanalization of the cervix. Outcomes in these cases are generally poor, since the natural functions of the cervix—such as mucus production and providing a barrier against ascending infection—cannot be replicated. Furthermore, the success rate of uterovaginal anastomosis is less than 50% and most patients require multiple surgeries while many develop<unk>  stenotis. Despite this, several pregnancies have been reported in women with<unk>  who underwent surgical treatment.
Cervical agenesis
Caudal regression syndrome
Supernumerary kidney
Iniencephaly
Uterine hypoplasia
Spina bifida
Vaginal atresia
Vaginal hypoplasia