<unk>  is usually an isolated illness, but can be associated with many other medical conditions. In anterior<unk> , no associated condition or syndrome is found in approximately one-half of cases. However, anterior<unk>  is often one of the syndromes associated with HLA-B27. Presence of this type of HLA allele has a relative risk of evolving this disease by approximately 15%. The most common form of<unk>  is acute anterior<unk>  (AAU). It is most commonly associated with HLA-B27, which has important features: HLA-B27 AAU can be associated with ocular inflammation alone or in association with systemic disease. HLA-B27 AAU has characteristic clinical features including male preponderance, unilateral alternating acute onset, a non-granulomatous appearance, and frequent recurrences, whereas HLA-B27 negative AAU has an equivalent male to female onset, bilateral chronic course, and more frequent granulomatous appearance. Rheumatoid arthritis is not uncommon in Asian countries as a significant association of<unk> . Noninfectious or autoimmune causes * Sympathetic ophthalmia * Behçet disease * Crohn's disease * Fuchs heterochromic iridocyclitis * Granulomatosis with polyangiitis * HLA-B27 related<unk>  * Spondyloarthritis (especially seen in ankylosing spondylitis) * Juvenile idiopathic arthritis * Sarcoidosis * Tubulointerstitial nephritis and<unk>  syndrome Infectious causes<unk>  may be an immune response to fight an infection inside the eye. While representing the minority of patients with<unk> , such possible infections include: *brucellosis *herpesviruses (herpes zoster ophthalmicus - shingles of the eye) *leptospirosis *Lyme disease *presumed ocular histoplasmosis syndrome *syphilis *toxocariasis *toxoplasmic chorioretinitis *tuberculosis *Zika fever Associated with systemic diseases Systemic disorders that can be associated with<unk>  include: *Enthesitis *Ankylosing spondylitis *Juvenile rheumatoid arthritis *psoriatic arthritis *reactive arthritis *Behçet's disease *inflammatory bowel disease *Whipple's disease *systemic lupus erythematosus *polyarteritis nodosa *Kawasaki's disease *chronic granulomatous disease *sarcoidosis *multiple sclerosis *Vogt–Koyanagi–Harada disease Drug related side effects *Rifabutin, a derivative of Rifampin, has been shown to cause<unk> . *Several reports suggest the use of quinolones, especially Moxifloxacin, may lead to<unk> . White Dot syndromes Occasionally,<unk>  is not associated with a systemic condition: the inflammation is confined to the eye and has unknown cause. In some of these cases, the presentation in the eye is characteristic of a described syndrome, which are called white dot syndromes, and include the following diagnoses: *acute posterior multifocal placoid pigment epitheliopathy *birdshot chorioretinopathy *multifocal choroiditis and panuveitis *multiple evanescent white dot syndrome *punctate inner choroiditis *serpiginous choroiditis *acute zonal occult outer retinopathy Masquerade syndromes Masquerade syndromes are those conditions that include the presence of intraocular cells but are not due to immune-mediated<unk>  entities. These may be divided into neoplastic and non-neoplastic conditions. *Non-neoplastic: :*retinitis pigmentosa :*intraocular foreign body :*juvenile xanthogranuloma :*retinal detachment *Neoplastic: :*retinoblastoma :*lymphoma :*malignant melanoma :*leukemia :*reticulum cell sarcoma
Uveitis
Glaucoma
Sinusitis
Laryngitis
Rhinitis
Aortitis
Pharyngitis
Uveoparotitis