The treatment's ionizing<unk>  is an activation mechanism for apoptosis (cell death) within the targeted cancer, but it can also impact nearby healthy radiosensitive tissues, like the lumbosacral plexus. The occurrence and severity of RILP is related to the magnitude of ionizing<unk>  and the radiosensitivity of peripheral nerves may be further aggravated when combined with chemotherapy, like taxanes and platinum drugs, during treatment.
Radiation-induced lumbar plexopathy
Complex regional pain syndrome
Spinal disc herniation
Calpainopathy
Lumbar disc disease
Nerve compression syndrome
Degenerative disc disease
Vascular myelopathy