Treatment of<unk>  is aimed at the specific symptoms presented in each individual. With the various symptoms of this disorder being properly managed and affected individuals having normal mental development,<unk>  is not a life - threatening condition and individuals are able to lead a near normal life with normal life expectancy. Treatment may involve the coordinated efforts of many healthcare professionals, such as pediatricians, orthopedists, dentists and/or other specialists depending on the symptoms. * Possible management options for short stature are surgical bone lengthening or growth hormone therapy. * Orthopedic techniques and surgery may be used to treat certain skeletal abnormalities. * Plastic surgery may also be performed on individuals to help correct certain cranio-facial anomalies. * Individuals with dental abnormalities may undergo corrective procedures such as braces or oral surgeries. Genetic counseling will be of benefit for affected individuals and their families. Family members of affected individuals should also receive regular clinical evaluations to detect any symptoms and physical characteristics that may be potentially associated with Three M syndrome or heterozygosity for the disorder. Other treatment for Three M syndrome is symptomatic and supportive. Once diagnosed the child should be seen and monitored for growth and pubertal progress and for consideration of growth hormone (GH) therapy. It is recommended every 6–12 months until achievement of final height. Adaptive aids for people with short stature and physiotherapy are possible treatment options. Newborns should have a hip ultrasound scan to screen for developmental dysplasia of the hip. Children can be treated can be treated with recombinant human GH (r-hGH). In genera, the response is modest, however a trial of treatment over 1 year may show a reasonable response. In this case, r-hGH should be continued long-term. Higher r-hGH doses have been used in individual cases. The issues of fertility should be discussed with male patients at the end of puberty and semen analysis offered.
3-M syndrome
3C syndrome
WHIM syndrome
RIDDLE syndrome
CAMFAK syndrome
HUPRA syndrome
STAR syndrome
TEMPI syndrome