External application of heat may cause surface burns. Tissue damage to a target organ with a regional treatment will vary with what tissue is heated (e.g. brain treated directly may injure the brain, lung tissue treated directly may cause pulmonary problems) Whole body<unk>  can cause swelling, blood clots, and bleeding. Systemic shock, may result, but is highly dependent upon method difference in achieving it. It may also cause cardiovascular toxicity. All techniques are often combined with radiation or chemotherapy, muddying how much toxicity is the result of those treatments versus the temperature elevation achieved.
Hyperthermia therapy
Infusion therapy
Peritoneovenous shunt
Extracorporeal shockwave therapy
Minimized extracorporeal circulation
Portosystemic shunt
Cerebral shunt
Vagotomy