Sedation and anesthesia In emergency settings,<unk>  can be used as a sedative hypnotic agent. It is used for conscious sedation and as a part of a rapid sequence induction to induce anaesthesia. It is used as an anaesthetic agent since it has a rapid onset of action and a safe cardiovascular risk profile, and therefore is less likely to cause a significant drop in blood pressure than other induction agents. In addition,<unk>  is often used because of its easy dosing profile, limited suppression of ventilation, lack of histamine liberation and protection from myocardial and cerebral ischemia. Thus,<unk>  is a good induction agent for people who are hemodynamically unstable.<unk>  also has interesting characteristics for people with traumatic brain injury because it is one of the only anesthetic agents able to decrease intracranial pressure and maintain a normal arterial pressure. In those with sepsis, one dose of the medication does not appear to affect the risk of death. Speech and memory test Another use for<unk>  is to determine speech lateralization in people prior to performing lobectomies to remove epileptogenic centres in the brain. This is called the<unk>  speech and memory test, or eSAM, and is used at the Montreal Neurological Institute. However, only retrospective cohort studies support the use and safety of<unk>  for this test. Steroidogenesis inhibitor In addition to its action and use as an anesthetic,<unk>  has also been found to directly inhibit the enzymatic biosynthesis of steroid hormones, including corticosteroids in the adrenal gland. As the only adrenal steroidogenesis inhibitor available for intravenous or parenteral administration, it is useful in situations in which rapid control of hypercortisolism is necessary or in which oral administration is unfeasible.
Etomidate
Metharbital
Sevoflurane
Esketamine
Remifentanil
Ketamine
Propofol
Methoxyflurane