Oxalate The buildup of oxalate in the body causes increased renal excretion of oxalate<unk> , which in turn results in kidney and bladder stones. Stones cause urinary obstruction (often with severe and acute pain), secondary infection of urine and eventually kidney damage.<unk>  is caused by genetic defects that result in the overproduction of oxalate. This is different from secondary<unk> , which is caused by the increase in dietary and intestinal absorption of oxalate or excessive intake of oxalate precursors. Oxalate stones in<unk>  tend to be severe, resulting in relatively early kidney damage (in teenage years to early adulthood), which impairs the excretion of oxalate leading to a further acceleration in accumulation of oxalate in the body. After the development of kidney failure patients may get deposits of oxalate in the bones, joints and bone marrow. Severe cases may develop haematological problems such as anaemia and thrombocytopaenia. The deposition of oxalate in the body is sometimes called "oxalosis" to be distinguished from "oxaluria" which refers to oxalate in the urine.
Primary hyperoxaluria
Hawkinsinuria
Cystinuria
Alkaptonuria
Alpha-aminoadipic and alpha-ketoadipic aciduria
Trimethylaminuria
Aspartylglucosaminuria
Homocystinuria