The enzymes in NexoBrid inhibit the liver enzymes CYP2C8 and CYP2C9 when ingested. These are involved in the breaking down of a number of drugs, including amiodarone, chloroquine, ibuprofen, and warfarin. It is not known whether this mechanism has any clinical relevance.
Bromelain 
Tetrodocain
Ibogaine
Noribogaine
Pramocaine
Iontocaine
Oxybuprocaine
Levobupivacaine