<unk>  is used to treat depression. This medication is in capsule or liquid and is taken by the mouth one to four times a day, with or without food. Usually people are started on a low dose and it is gradually increased. A level between 50-150 ng/mL of<unk>  in the blood generally corresponds with an antidepressant effect. In the United Kingdom, it may also be used for treating nocturnal enuresis, with courses of treatment lasting no more than three months. It is also used off-label for the treatment of panic disorder, irritable bowel syndrome, migraine prophylaxis and chronic pain or neuralgia modification, particularly temporomandibular joint disorder. Neuropathic pain Although not approved by the FDA for neuropathic pain, many randomized controlled trials have demonstrated the effectiveness of TCAs for the treatment of this condition in both depressed and non-depressed individuals. In 2010, an evidence-based guideline sponsored by the International Association for the Study of Pain recommended<unk>  as a first-line medication for neuropathic pain. However, in a 2015 Cochrane systematic review the authors did not recommend<unk>  as a first-line agent for neuropathic pain. Irritable Bowel Syndrome<unk>  has also been used as an off-label treatment for Irritable Bowel Syndrome, or IBS.
Nortriptyline
Amitriptyline
Venlafaxine
Atomoxetine
Guanfacine
Fluoxetine
Nabilone
Naltrexone