The binding of ligands to the androgen<unk>  (AR) results in a conformational change, this consequentially alters surface topology which will lead to tissue-specific gene regulation. This tissue-specific regulation then allows for the<unk>  stimulation or inhibition of the AR; this requires androgen response elements, co-regulators, and transcription factors. Although the exact mechanisms still remain unclear, tissue specificity and complexity of the pathway is known to dictate the transcriptional and cellular response.
Selective androgen receptor modulator
Selective estrogen receptor modulator
Selective estrogen receptor degrader
Selective androgen receptor degrader
Aromatase inhibitor
Steroidal aromatase inhibitor
N-Terminal domain antiandrogen
Antiandrogen