There are a variety of symptoms that can occur in children. Infants with microcephaly are born with either a normal or reduced head size. Subsequently, the head fails to grow, while the face continues to develop at a normal rate, producing a child with a small head and a receding forehead, and a loose, often wrinkled scalp. As the child grows older, the smallness of the skull becomes more obvious, although the entire body also is often underweight and dwarfed. Severely impaired intellectual development is common, but disturbances in motor functions may not appear until later in life. Affected newborns generally have striking neurological defects and seizures. Development of motor functions and speech may be delayed. Hyperactivity and intellectual disability are common occurrences, although the degree of each varies. Convulsions may also occur. Motor ability varies, ranging from clumsiness in some to spastic quadriplegia in others.
symptom of Adenylosuccinate lyase deficiency
symptom of Pyruvate carboxylase deficiency
symptom of Glucose-6-phosphate dehydrogenase deficiency
symptom of Phenylketonuria
symptom of Dubin–Johnson syndrome
complications of Pyruvate carboxylase deficiency
symptom of Beta-mannosidosis
medical cause of Neonatal jaundice