<unk> s, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) (i.e., GABA analogues) which block α2δ subunit-containing voltage-dependent calcium channels (VDCCs). This site has been referred to as the gabapentin receptor (α2δ subunit), as it is the target of the drugs gabapentin and pregabalin. Clinically used<unk> s include gabapentin, pregabalin, and mirogabalin, as well as a gabapentin prodrug, gabapentin enacarbil. Additionally, phenibut has been found to act as a<unk>  in addition to its action of functioning as a GABAB receptor agonist. Further analogues like imagabalin are in clinical trials but have not yet been approved. Other<unk> s which are used in scientific research but have not been approved for medical use include atagabalin, 4-methylpregabalin and PD-217,014.
Gabapentinoid
Antidote
Antipsychotic
Antimanic drugs
Neuroleptanalgesic
Benzodiazepine
Antiprion drug
Tricyclic antidepressant