+ Hip fractures per 1000 person-years WHO category Age 50–64 Age > 64 Overall Normal 5.3 9.4 6.6 Osteopenia 11.4 19.6 15.7 Osteoporosis 22.4 46.6 40.6 Although people with osteoporosis have increased mortality due to the<unk>  of fracture, the fracture itself is rarely lethal. Hip fractures can lead to decreased mobility and additional risks of numerous<unk>  (such as deep venous thrombosis and/or pulmonary embolism, and pneumonia). The six-month mortality rate for those aged 50 and above following hip fracture was found to be around 13.5%, with a substantial proportion (almost 13%) needing total assistance to mobilize after a hip fracture. Vertebral fractures, while having a smaller impact on mortality, can lead to severe chronic pain of neurogenic origin, which can be hard to control, as well as deformity. Though rare, multiple vertebral fractures can lead to such severe hunchback (kyphosis), the resulting pressure on internal organs can impair one's ability to breathe. Apart from risk of death and other<unk> , osteoporotic fractures are associated with a reduced health-related quality of life. The condition is responsible for millions of fractures annually, mostly involving the lumbar vertebrae, hip, and wrist. Fragility fractures of ribs are also common in men. Fractures Hip fractures are responsible for the most serious consequences of osteoporosis. In the United States, more than 250,000 hip fractures annually are attributable to osteoporosis. A 50-year-old white woman is estimated to have a 17.5% lifetime risk of fracture of the proximal femur. The incidence of hip fractures increases each decade from the sixth through the ninth for both women and men for all populations. The highest incidence is found among men and women ages 80 or older. Between 35 and 50% of all women over 50 had at least one vertebral fracture. In the United States, 700,000 vertebral fractures occur annually, but only about a third are recognized. In a series of 9704 women aged 68.8 on average studied for 15 years, 324 had already suffered a vertebral fracture at entry into the study and 18.2% developed a vertebral fracture, but that risk rose to 41.4% in women who had a previous vertebral fracture. In the United States, 250,000 wrist fractures annually are attributable to osteoporosis. Wrist fractures are the third most common type of osteoporotic fractures. The lifetime risk of sustaining a Colles' fracture is about 16% for white women. By the time women reach age 70, about 20% have had at least one wrist fracture. Fragility fractures of the ribs are common in men as young as age 35. These are often overlooked as signs of osteoporosis, as these men are often physically active and suffer the fracture in the course of physical activity, such as falling while water skiing or jet skiing.
complications of Kallmann syndrome
onset of Kallmann syndrome
complications of Klinefelter syndrome
medical cause of Hyperdontia
medical cause of Precocious puberty
complications of Growth hormone deficiency
symptom of Kallmann syndrome
complications of Prader–Willi syndrome