The adverse effects of<unk>  are also related to the drug's cardiovascular effects.<unk>  can produce tachycardia (an elevated heart rate), which predisposes people who take it to cardiac arrhythmias. Pharmacodynamics<unk>  is a β1 and β2 adrenoreceptor agonist and has almost no activity on alpha adrenergic receptors. Its agonist effects at TAAR1 provide it with pharmacodynamic effects that resemble those of the endogenous trace amines, like tyramine." Table 1: EC50 values of different agonists at hTAAR1, hADRB1 and hADRB2."<unk> 's effects on the cardiovascular system (non-selective) relate to its actions on cardiac β1 receptors and β2 receptors on smooth muscle within the tunica media of arterioles.<unk>  has positive inotropic and chronotropic effects on the heart. β2 adrenoceptor stimulation in arteriolar smooth muscle induces vasodilation. Its inotropic and chronotropic effects elevate systolic blood pressure, while its vasodilatory effects tend to lower diastolic blood pressure. The overall effect is to decrease mean arterial pressure due to the β2 receptors' vasodilation. The<unk> ropylamine group in<unk>  makes it selective for β receptors. The free catechol hydroxyl groups keep it susceptible to enzymatic metabolism. Pharmacokinetics The plasma half-life for<unk>  is approximately two minutes.
Isoprenaline
Hexoprenaline
Nadolol
Eplerenone
Adrenaline
Oxprenolol
Sodium nitroprusside
Atenolol