There is a risk of development of cancer with<unk> , but it varies based on the underlying cause of the<unk> . The risk is highest with congenital<unk>  syndromes, and is lowest in acquired causes. As a result, it is recommended that patients with multiple<unk>  polyps have a colonoscopy to evaluate the colon. If there are polyps seen on colonoscopy, genetic testing and testing of family members is recommended. In the gastric adenocarcinoma associated with proximal<unk>  of the stomach (GAPPS), there is a high risk of early development of proximal gastric adenocarcinoma. It is still unclear which patients would benefit with surveillance gastroscopy, but most physicians recommend endoscopy every one to three years to survey polyps for dysplasia or cancer. In the event of high grade dysplasia, polypectomy, which is done through the endoscopy, or partial gastrectomy may be recommended. One study showed the benefit of NSAID therapy in regression of gastric polyps, but the efficacy of this strategy (given the side effects of NSAIDs) is still dubious.
Fundic gland polyposis
Macular corneal dystrophy
Congenital cataract
Corneal dystrophy
Ocular melanosis
Otosclerosis
Subepithelial mucinous corneal dystrophy
Vitreous bulge