The most commonly observed adverse effect is mild bone pain after repeated administration, and local skin reactions at the site of injection. Other observed adverse effects include serious allergic reactions (including a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, and sweating), ruptured spleen (sometimes resulting in death), alveolar hemorrhage, acute respiratory distress syndrome, and hemoptysis. Severe sickle cell crises, in some cases resulting in death, have been associated with the use of<unk>  in patients with sickle cell disorders.
Filgrastim
Lipegfilgrastim
Pegfilgrastim
Romiplostim
Granulocyte colony-stimulating factor
Interferon
Granulocyte-macrophage colony-stimulating factor
Trimetrexate