<unk>  is defined as an elevated resting energy expenditure (REE) > 110% of predicted REE.<unk>  is accompanied by a variety of internal and external symptoms, most notably extreme weight loss, and can also be a symptom in itself. This state of increased metabolic activity can signal underlying issues, especially hyperthyroidism. Patients with Fatal familial insomnia, an extremely rare and strictly hereditary disorder, also presents with<unk> ; however, this universally fatal disorder is exceedingly rare, with only a few known cases worldwide. The drastic impact of the hypermetabolic state on patient nutritional requirements is often understated or overlooked as well.
Hypermetabolism
Osteomimicry
Adiadochokinesia
Alpha cell hyperplasia
Starvation
Hypoestrogenism
Corticosteroid-induced lipodystrophy
Neuroendocrine hyperplasia