Women who are administered<unk>  may experience virilization, irreversible development of masculine features such as voice deepening, hirsutism, menstruation abnormalities, male-pattern hair loss, and clitoral enlargement.<unk>  may disrupt growth in children, reducing their adult height. Because of these side effects, doses given to women and children are minimized and people are usually monitored for virilization and growth abnormalities. Like other androgens,<unk>  can cause or worsen acne and priapism (unwanted or prolonged erections).<unk>  can also reduce males' fertility, another side effect common among androgens. In an attempt to compensate for the exogenous increase in androgens, the body may reduce testosterone production via testicular atrophy and inhibition of gonadotropic activity. Unlike some AAS,<unk>  does not generally cause gynecomastia because it is not aromatized into estrogenic metabolites. However, although no reports of gynecomastia were made in spite of widespread use,<unk>  was reported in a publication in 1991 to have been associated with 33 cases of gynecomastia in adolescent boys treated with it for short stature. The gynecomastia developed during<unk>  therapy in 19 of the boys and after the therapy was completed in 14 of the boys, and 10 of the boys had transient gynecomastia, while 23 had persistent gynecomastia that necessitated mastectomy. Though transient gynecomastia is a natural and common occurrence in pubertal boys, the gynecomastia associated with<unk>  was of a late/delayed onset and was persistent in a high percentage of the cases. As such, the researchers stated, "although<unk>  cannot be implicated as stimulatory in gynecomastia", a possible relationship should be considered in clinicians using<unk>  in adolescents for growth stimulation. Uniquely among 17α-alkylated AAS,<unk>  shows little to no hepatotoxicity, even at high doses. No cases of severe hepatotoxicity have been singularly attributed to<unk> . However, elevated liver enzymes have been observed in some people, particularly with high doses and/or prolonged treatment, although they return to normal ranges following discontinuation.
Oxandrolone
Norethandrolone
Nandrolone
Gestrinone
Nandrolone propionate
Allenestrol
Mestanolone
Androstanolone