Benzodiazepines bind to a specific benzodiazepine receptor, thereby enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) and causing CNS depression. In<unk>  situations this pharmacological effect is extended leading to a more severe CNS depression and potentially coma or cardiac arrest.<unk> -related coma may be characterised by an alpha pattern with the central somatosensory conduction time (CCT) after median nerve stimulation being prolonged and the N20 to be dispersed. Brain-stem auditory evoked potentials demonstrate delayed interpeak latencies (IPLs) I-III, III-V and I-V. Toxic<unk> s of benzodiazepines therefore cause prolonged CCT and IPLs.
Benzodiazepine overdose
Opioid overdose
Tricyclic antidepressant overdose
Cocaine intoxication
Nicotine withdrawal
Carbamate poisoning
Benzodiazepine withdrawal syndrome
Drug withdrawal