The most common symptoms of<unk>  are mild to severe developmental delays with absent or limited speech, seizures, short stature, sparse hair, typical facial characteristics, brachydactyly, and prominent finger joints and broad distal phalanges. Major Features of NCBRS * Mild prenatal growth retardation * Moderate postnatal growth retardation * Mild to severe developmental delay * Severely impaired speech * Seizures *Microcephaly * Sparse hair * Progressive skin wrinkling * Thick, anteverted alae nasi * Long and broad philtrum * Large mouth * Thin upper and thick lower vermilion * Progressive prominence of distal phalanges * Progressive prominence of inter-phalangeal joints * Scoliosis * Short metacarpals–metatarsals Pictures of the hands of NCBRS Pictures of the feet of NCBRS
Nicolaides–Baraitser syndrome
Cortes Lacassie syndrome
Grisel's syndrome
Menke-Hennekam syndrome
Weber's syndrome
Vogt–Koyanagi–Harada disease
Fryns-Aftimos syndrome
Renpenning's syndrome