Although no cure for this disease has been found, improvements in the course of the disease have been significantly seen after the administration of nutritional and vitamin supplements, especially in children. It is stated that if there is no remission by about 12-18. months of childhood, liver transplantation is necessary at a later age. Neonatal cholestasis lasted no more than one year in some patients or lasted until the age of 6/7 years in some cases. In recent decades, cholestatic episodes have lasted a shorter time than before 1970. There has also been a decline in rickets, growth retardation, and neuropathy over time. The reasons for this are improved nutritional habits, vitamin and cholestyramine supplementation. Nevertheless, it is not yet possible to prevent serious liver disease.
Aagenaes syndrome
Koolen–De Vries syndrome
Pelger–Huët anomaly
Barakat-Perenthaler syndrome
Wildervanck syndrome
Van der Woude syndrome
Van Den Bosch syndrome
Laron syndrome