There are few side effects related to the use of<unk> s; the most common are constipation or diarrhea, headache, and dizziness. Unlike antihistamines with antiemetic properties such as cyclizine,<unk> s do not produce sedation, nor do they cause extrapyramidal effects, as phenothiazines (such as prochlorperazine) sometimes do. All<unk> s have been associated with asymptomatic electrocardiogram changes, such as prolongation of the PT and QTc intervals and certain arrhythmias. The clinical significance of these side effects is unknown.
5-HT3 antagonist
Opioid antagonist
Dopamine antagonist
Dopamine agonist
GABA reuptake inhibitor
Adenosine reuptake inhibitor
5-HT2C receptor agonist
NMDA receptor antagonist