<unk>  (rINN, marketed under the trade name Amitiza among others) is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company. The drug was developed by Sucampo Pharmaceuticals and approved by the Food and Drug Administration (FDA) in 2006. It was recommended for use in the UK by the National Institute for Health and Care Excellence (NICE) in July 2014. Health Canada approved the drug in 2015. The cost to the NHS was £29.68 per 24 mcg 28-cap pack as of April 2017.<unk>  received approval from the Food and Drug Administration in 2008 to treat irritable bowel syndrome with constipation (IBS-C), and in 2013 for the treatment of OIC in adults with chronic noncancer pain. It is available through prescription only. The drug is available in the United States, Japan, Switzerland, India, Bangladesh, United Kingdom, and Canada. In Bangladesh and India,<unk>  is marketed under the trade name Lubigut by Ziska Pharmaceuticals, Lubilax by Beacon Pharmaceuticals, and under the trade name Lubowel by Sun Pharmaceutical.
Lubiprostone
Androstanolone
Norethandrolone
Protollin
Androstanolone benzoate
Nandrolone
Testosterone undecylenate
Norbormide