Presence of an ovarian<unk>  plus hormonal disturbances suggests a<unk> , granulosa cell<unk>  or thecoma. However, hormonal disturbances, in<unk><unk> s, is present in only 2/3 of cases. Testicular<unk> s can be detected sonographically, ultrasound examinations may be ordered in the event of a palpable scrotal lump, however incidental identification of these lesions is also possible. Histopathology of a<unk> , high magnification, H&E stain, showing a typical histopathology:- Diffuse architecture (may also be nodular with fibrous bands)- Polygonal cells with abundant eosinophilic granular cytoplasm- Uniform round nuclei and prominent central nucleoli. A conclusive diagnosis is made via histology, as part of a pathology report made during or after surgery. Reinke crystals are classically found in these<unk> s and help confirm the diagnosis, although they are seen in less than half of all<unk> s. Immunohistochemical markers of<unk> s include inhibin-alpha, calretinin, and melan-A.
Leydig cell tumour
Gonadoblastoma
Sertoli cell tumour
Granulosa cell tumour
Seminoma
Ovarian fibroma
Theca lutein cyst
Mixed Müllerian tumor