Skin use<unk>  is most commonly used to treat acne, both inflammatory and noninflammatory. Multiple studies support the efficacy of topical retinoids in the treatment of acne vulgaris. It is sometimes used in conjunction with other topical acne medications to enhance their penetration. In addition to treating active acne, retinoids accelerate the resolution of acne-induced postinflammatory hyperpigmentation. It is also useful as maintenance therapy for people who have responded to their initial treatment, reducing the prolonged use of antibiotics for acne. Leukemia<unk>  is used to induce remission in people with acute promyelocytic leukemia who have a mutation (the t(15;17)<unk> nslocation 160 and/or the presence of the PML/RARα gene) and who do not respond to anthracyclines or cannot take that class of drug. It is not used for maintenance therapy. The evidence is very uncertain about the effect of<unk>  in addition to chemotherapy for patients with an acute myeloid leukemia on diarrhoea, nausea/vomiting and heart-related toxicity grades III/IV. Furthermore,<unk>  in addition to chemotherapy probably results in little to no difference in the mortality, relapse, progress, mortality during the trial and infections grade III/IV. Photoaging Photoaging is premature skin aging resulting from prolonged and repeated exposure to solar radiation. Features of photoaging include fine and coarse wrinkles, change in skin pigmentation, and loss of elasticity. In human skin, topical retinoids increase collagen production, induce epidermal hyperplasia, and decrease keratinocyte and melanocyte atypia. Topical<unk>  is the most extensively investigated retinoid therapy for photoaging. Topical<unk>  can be used for mild to severe photoaging in people of all skin types. Several weeks or months of use are typically required before improvement is appreciated. The benefits of topical<unk>  are lost upon discontinuation. Although it has only been studied for a duration of two years, it may be continued indefinitely. A long-term maintenance regimen with a lower concentration or less frequent application may be an alternative to continued use.
Tretinoin
Alitretinoin
Isotretinoin
Clobetasol
Clobetasol propionate
Ulobetasol propionate
Urodilatin
Bexarotene