<unk>  <unk>  is a rare blood cell disease which is characterized by<unk>  of fragments of infection-fighting immunoglobulins, called<unk><unk> s (LCs), in the body. LCs are normally cleared by the kidneys, but in<unk> , these<unk><unk>  deposits damage organs and cause disease. The kidneys are almost always affected and this often leads to kidney failure. About half of people with<unk>  also have a plasma cell dyscrasia, a spectrum of diseases that includes multiple myeloma, Waldenström's macroglobulinemia, and the monoclonal gammopathy of undetermined significance premalignant stages of these two diseases. Unlike in AL amyloidosis, in which<unk><unk> s are laid down in characteristic amyloid deposits, in<unk> ,<unk><unk> s are deposited in non-amyloid granules.
Light chain deposition disease
Heavy chain disease
AL amyloidosis
Familial renal amyloidosis
AA amyloidosis
IgG4-related disease
Thin basement membrane disease
HIV-associated nephropathy