If no specific therapy is initiated, in 94% of patients the disease is fatal within 10–20 years following diagnosis. * Currently, benzimidazoles (such as albendazole) are used to treat AE: only halt their proliferation and do not actually kill the parasites, side effects such as liver damage * 2-ME2, a natural metabolite of estradiol, is tested with some results in vitro: decreased transcription of 14-3-3-pro-tumorogenic zeta-isoform, causes damage to germinal layer but does not kill parasite in vivo * Treatment with a combination of albendazole/2-ME2 showed best results in reducing parasite burden * Despite the improvements in the chemotherapy of<unk> is with benzimidazole derivatives, complete elimination of the parasitic mass cannot be achieved in most infected patients, although studies indicate that long-term treatment with mebendazole typically increases the survival rate..
Echinococcus multilocularis
Echinostoma revolutum
Toxocara malayasiensis
Toxocara cati
Echinostoma cinetorchis
Taenia asiatica
Taenia solium
Neorickettsia helminthoeca