Acute toxicity studies have not indicated a risk of acute side effects with overdose of<unk> . The median lethal dose (LD50) of<unk>  in mice is approximately 700 mg/kg.<unk>  has been administered in total amounts of 2,000 to 3,000 mg over several months in patients with cancer without toxicity observed. The most likely sign of overdose is reversible feminization, namely gynecomastia. Other symptoms of estrogen overdosage may include nausea, vomiting, bloating, increased weight, water retention, breast tenderness, vaginal discharge, heavy legs, and leg cramps. These side effects can be diminished by reducing the estrogen dosage. There is no specific antidote for overdose of<unk> . Treatment of<unk>  overdose should be based on symptoms.
Polyestradiol phosphate
Polyestriol phosphate
Progestogen ester
Androgen ester
Progestogen 
Progestogen
Estradiol sulfate
Estrogen ester