Structure of<unk>  The<unk>  particle<unk> onsists of a lipid membrane envelope that is 55 to 65 nm in diameter. Two viral envelope glycoproteins, E1 and E2, are embedded in the lipid envelope. They take part in viral attachment and entry into the<unk> ell. Within the envelope is an icosahedral<unk> ore that is 33 to 40 nm in diameter. Inside the<unk> ore is the RNA material of the virus. E1 and E2 glycoproteins E1 and E2 are<unk> ovalently bonded when embedded in the envelope of<unk>  and are stabilized by disulfide bonds. E2 is globular and seems to protrude 6 nm out from the envelope membrane according to electron microscope images. These glycoproteins play an important role in the interactions hepatitis<unk>  has with the immune system. A hypervariable region, the hypervariable region 1 (HVR1)<unk> an be found on the E2 glycoprotein. HVR1 is flexible and quite accessible to surrounding molecules. HVR1 helps E2 shield the virus from the immune system. It prevents<unk> D81 from latching onto its respective receptor on the virus. In addition, E2<unk> an shield E1 from the immune system. Although HVR1 is quite variable in amino acid sequence, this region has similar<unk> hemical, physical, and<unk> onformational<unk> haracteristics across many E2 glycoproteins.
Hepatitis C virus
Hepatitis B virus
Hepatitis F virus
Influenza B virus
Dhori virus
Rubella virus
Hendra virus
Human T-lymphotropic virus 2