<unk>  is a genetic disorder affecting around 1 in 5,000-10,000 children, characterized by glomerulonephritis, end-stage kidney disease, and hearing loss.<unk>  can also affect the eyes, though the changes do not usually affect vision, except when changes to the lens occur in later life. Blood in urine is universal. Proteinuria is a feature as kidney disease progresses. The disorder was first identified in a British family by the physician Cecil A.<unk>  in 1927.<unk>  once also had the label hereditary nephritis, but this is misleading as there are many other causes of hereditary kidney disease and 'nephritis'.<unk>  is caused by an inherited defect in type IV collagen—a structural material that is needed for the normal function of different parts of the body. Since type IV collagen is found in the ears, eyes, and kidneys, this explains why<unk>  affects different seemingly unrelated parts of the body (ears, eyes, kidneys, etc.).
Alport syndrome
Cystic kidney disease
Balkan endemic nephropathy
IgA nephropathy
Uddanam nephropathy
Sickle cell nephropathy
Mesoamerican nephropathy
Malarial nephropathy