<unk> s in children constitute a group of rare disorders that are characterised by tissue hypertrophy. Individual<unk> s have been shown to overlap with regard to clinical and radiologic features. The details of the genetic bases of these syndromes are unfolding. Any of the three embryonic tissue layers may be involved. The syndromes may manifest in localized or generalized tissue<unk> . Latitudinal and longitudinal growth may be affected. Nevertheless, the musculoskeletal features are central to the diagnosis of some syndromes such as Proteus syndrome. The time of presentation of children with<unk> s is an important contributor to the differential diagnosis. Children with some<unk> s such as Klippel–Trénaunay–Weber syndrome can be readily detectable at birth. In contrast, other<unk> s such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. In general, children with<unk> s are at increased risk of embryonic tumor development.
Overgrowth syndrome
Primordial dwarfism
Ablepharon macrostomia syndrome
Constitutional growth delay
Achondroplasia
Dwarfism
Neonatal hypocalcemia
Caudal regression syndrome