<unk> , sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder, and social phobia. It may also be used for chronic pain. It is taken by mouth. Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, priapism and sexual problems. Severe side effects include an increased risk of suicide, mania, and serotonin syndrome. Antidepressant withdrawal syndrome may occur if stopped. There are concerns that use during the later part of pregnancy can harm the baby. How it works is not entirely clear, but it seems to be related to the potentiation of the activity of some neurotransmitters in the brain.<unk>  might have alpha and beta blocking properties, depending on the dosage and the CYP2D6 metabolism of each user, resulting in adverse events like bradycardia or priapism.<unk>  was approved for medical use in the United States in 1993. It is available as a generic medication. In 2019, it was the 40th most commonly prescribed medication in the United States with more than 17million prescriptions.
Venlafaxine
Desvenlafaxine
Nortriptyline
Atomoxetine
Fluoxetine
Amitriptyline
Citalopram
Imipramine