<unk> , also called hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, is a rare autosomal recessive urea cycle disorder affecting the enzyme<unk><unk> , which causes ammonia to accumulate in the blood, a condition called hyperammonemia. Ammonia, which is formed when proteins are broken down in the body, is toxic if the levels become too high. The nervous system is especially sensitive to the effects of excess ammonia.
Ornithine translocase deficiency
Holocarboxylase synthetase deficiency
Guanidinoacetate methyltransferase deficiency
Carbamoyl phosphate synthetase I deficiency
Malonyl-CoA decarboxylase deficiency
Aminoacylase 1 deficiency
Arginine:glycine amidinotransferase deficiency
Adenylosuccinate lyase deficiency