The<unk> <unk> , formerly called the<unk>  Toxicity<unk>  (CTC or NCI-CTC), are a set of<unk>  for the standardized classification of adverse effects of drugs used in cancer therapy. The<unk>  system is a product of the US National Cancer Institute (NCI). The current version 5.0 was released on November 27, 2017. Many clinical trials, now extending beyond oncology, encode their observations based on the<unk>  system. It uses a range of grades from 1 to 5. Specific conditions and symptoms may have values or descriptive<unk> t for each level, but the general guideline is: :1 - Mild :2 - Moderate :3 - Severe :4 - Life-threatening :5 - Death See Reference for full details on the current<unk> .
Common Terminology Criteria for Adverse Events
Sentinel event
Clinical endpoint
Safety pharmacology
Clinical pathway
Adverse outcome pathway
Inclusion and exclusion criteria
Clinical trial naming conventions