<unk>  management algorithm from the Centers for Disease Control and Prevention Diagnosis is usually based on serology (looking for an antibody response) rather than looking for the organism itself. Serology allows the detection of chronic infection by the appearance of high levels of the antibody against the virulent form of the bacterium. Molecular detection of bacterial DNA is increasingly used. Contrary to most obligate intracellular parasites, Coxiella burnetii can be grown in an axenic culture, but its culture is technically difficult and not routinely available in most microbiology laboratories.<unk>  can cause endocarditis (infection of the heart valves) which may require transoesophageal echocardiography to diagnose.<unk>  hepatitis manifests as an elevation of alanine transaminase and aspartate transaminase, but a definitive diagnosis is only possible on liver biopsy, which shows the characteristic fibrin ring granulomas.
Q fever
Leptospirosis
Dysentery
Dengue fever
Enterotoxemia
Malaria
Fever of unknown origin
Pneumonia