In terms of chemical structure, it is similar to tricyclic antidepressants (TCAs), but it has significantly different pharmacology and important structural differences, so it is not usually grouped with them. Analogues Although several related compounds are disclosed in the original patent, no activity data are provided and it was unclear whether these share<unk> 's unique pharmacological effects. More recent structure-activity relationship studies have since been conducted, providing some further insight on μ-opioid, δ-opioid, and pharmacokinetical activity. Derivatives where the aromatic chlorine substituent is replaced by bromine, iodine or methylthio, and/or the heptanoic acid tail is varied in length or replaced with other groups such as 3-methoxypropyl, show similar or increased opioid receptor activity relative to<unk>  itself. Amineptine, the most closely related drug to have been widely studied, is a dopamine reuptake inhibitor with no significant effect on serotonin levels, nor opioid agonist activity.<unk> line, analog of<unk> , is a notable class I HDAC inhbitor.
Tianeptine
Droperidol
Galantamine
Rivastigmine
Cupiennin
Gliquidone
Tripelennamine
Bromperidol decanoate