The probability of primitive<unk>  tumors to have recurrence and metastasize through cerebrospinal fluid is relatively high. The outcome of PNET is more positive when the individual is an adult, independent of age subgroups, or an older child. Less than 50% of children survive more than 5 years, while the majority of adults live to 7 years. The reason the prognosis for such tumor is worst in children is due to the higher probability of the tumor spreading to the rest of the<unk><unk>  through the cerebrospinal fluid and growing again. Moreover, children have the probability of developing deficiencies in cognitive processes, problems in the endocrine<unk> , and psychological obstacles after the disease. Adults, on the other hand, don't show such propensity. As a consequence, 37.7% of children affected by the tumor live to 4 years. The effect of treatment strategies such as chemotherapy and radiation therapy on the prognosis of the disease is still controversial, with studies claiming either their benefits or their ineffectiveness. The same holds true for the relationship between volume of tumor removed by surgery and survival. Furthermore, factors such as tumor size, location of origin, race, and sex of individual don't show any influence on the outcome of the disease. However, interactions of some factors such as tumor site, age, and treatment strategy can affect one's prognosis. For instance, when younger children below the age of 3 suffering from tumors originating in places other than the pineal gland are treated with chemotherapy, they present better outcomes than those suffering from pineal tumors and treated with chemotherapy.
Central nervous system primitive neuroectodermal tumor
Central nervous system cyst
Extracranial germ cell tumor
Pediatric ependymoma
Primary central nervous system lymphoma
Primitive neuroectodermal tumor
Glial tumor
Central neurocytoma