Like the allylamine antifungals,<unk>  works by inhibiting the synthesis of ergosterol by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes. Lacking ergosterol, the cell membranes increase in permeability, allowing their contents to leak out. Furthermore, inhibition of squalene epoxidase leads to a toxic buildup of squalene. This double action of<unk>  (increased membrane permeability and toxic buildup of squalene) makes<unk>  fungicidal rather than merely fungistatic. In addition to being an antifungal,<unk>  is an anti inflammatory. Because fungal skin infections are often accompanied by significant inflammation, this is a desirable property. The fact that<unk>  has intrinsic anti inflammatory properties is also desirable since it is not necessary to add cortical steroids (which decrease the ability to fight infection) to reduce inflammation.
Butenafine
Rupatadine
Olopatadine
Loratadine
Patiromer
Mibolerone
Proxicromil
Ridinilazole