BCDS is inherited in an X-linked dominant manner. This means the defective gene responsible for the disorder is located on the X chromosome, and only one copy of the defective gene is sufficient to cause the disorder when inherited from a parent who has the disorder. Males are normally hemizygous for the X chromosome, having only one copy. As a result, X-linked dominant disorders usually show higher expressivity in males than females. As the X chromosome is one of the sex chromosomes (the other being the Y chromosome), X-linked inheritance is determined by the sex of the parent carrying a specific gene and can often seem complex. This is because, typically, females have two copies of the X-chromosome, while males have only one copy. The difference between dominant and recessive inheritance patterns also plays a role in determining the chances of a child inheriting an X-linked disorder from their parentage.A locus of Xq24-q27 has been described. However, no gene has been identified.
Bazex–Dupré–Christol syndrome
Zadik–Barak–Levin syndrome
Neu–Laxova syndrome
Cronkhite–Canada syndrome
Nicolau–Balus syndrome
Wallis–Zieff–Goldblatt syndrome
Banki syndrome
Zamzam–Sheriff–Phillips syndrome