Treatment of RILP is primarily supportive with mental, physiological and social aspects and consideration of any aggravating (synergistic) neurological factors. To prevent compounding existing RILP symptoms and to minimize further progression *Remove co-morbidity factors *control diabetes and hypertension *avoid excessive alcohol use *avoiding any local trauma in the irradiated volume *controlling acute edema *control acute inflammation. Pharmaceuticals that may be effective are corticosteroids (Dexamethasone) *avoid stretching a plexus immobilized by fibrosis, e.g., carrying heavy loads or extensive movements, which may cause sudden neurological decompensation. The effect on the person with the condition, depends upon the type of impairment. Handicaps may include physical challenges, bowel and/or bladder dysfunction and may occur in multiple settings of work and home. Physical and occupational therapy are important elements in maintaining mobility and use of the lower extremities, along with assistive aides such as Ankle-Foot-Orthotics (AFOs), cane, walkers, etc. Sensory reeducation techniques may be necessary for balance and lymphedema management may be required. Pharmaceuticals that may be effective for RILP's neuropathic pain are *tricyclic antidepressants (TCAs) (amitriptyline) *Antiepileptics or anticonvulsants (gabapentin, pregabalin, carbamazepine, valproic acid) *Selective serotonin re-uptake inhibitors(SSRIs) (duloxetine) to preserve normal norepinephrine and serotonin levels *Analgesic drugs (pregabalin, methadone) *Opiates may used singularly or to potentate the concomitant use of TCAs. *Antiarrhythmics (mexilitine) for muscle stiffness Non-pharmaceutical RILP considerations are *acupuncture for pain *massage for pain *transcutaneous electrical nerve stimulation (TENS) for pain *Benzodiazepines may be used for paraesthesia *quinine may be used for cramps Functional impairment and residual pain can lead to social isolation. Cancer support groups are valuable resources to learn about the syndrome and therapeutic options, and are a means to voice emotions related to having cancer and surviving it.
Radiation-induced lumbar plexopathy
Complex regional pain syndrome
Spinal disc herniation
Calpainopathy
Lumbar disc disease
Nerve compression syndrome
Degenerative disc disease
Vascular myelopathy