<unk>  <unk> , also known as<unk> ivated coagulation time, is a test of coagulation. The<unk>  test can be used to monitor anticoagulation effects, such as from high-dose heparin before, during, and shortly after procedures that require intense anticoagulant administration, such as cardiac bypass, interventional cardiology, thrombolysis, extra-corporeal membrane oxygenation (ECMO), and continuous dialysis. It measures the seconds needed for whole blood to clot upon<unk> ivation of the intrinsic pathway by the addition of factor XII<unk> ivators. The clotting time is based on a relative scale and requires a baseline value for comparison due to inconsistencies between the source and formulation of the<unk> ivator being used. It is usually ordered in situations where the partial thromboplastin time (PTT) test may take an excessive amount of time to process or is not clinically useful. Prolongation of the<unk>  may indicate a deficiency in coagulation factors, thrombocytopenia, or platelet dysfunction. Clotting time measurements can be affected by drugs such as warfarin, aprotinin, and GpIIb/IIIa inhibitors, and physiologic disturbances such as hypothermia, hypervolemia, and hypovolemia.
Activated clotting time
Thrombin time
Partial thromboplastin time
Prothrombin time
Kaolin clotting time
Ecarin clotting time
Thrombin generation assay
Reptilase time