Example of writing by a patient with Parkinson's disease that is possibly showing<unk> in addition to other abnormal characteristics. Published by Jean-Martin Charcot in 1879.<unk> is an acquired disorder that features abnormally small, cramped handwriting or the progression to progressively smaller handwriting. It is commonly associated with neurodegenerative disorders of the basal ganglia, such as in Parkinson's disease, but it has also been ascribed to subcortical focal lesions. O'Sullivan and Schmitz describe it as an abnormally small handwriting that is difficult to read, as seen in the photo to the right.<unk> is also seen in patients with Wilson's disease, Obsessive Compulsive Disorder, Metamorphopsia, or with isolated focal lesions of the midbrain or basal ganglia.
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