A<unk>  is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended from a single mutated cell (monoclonality), as would typically define a benign neoplasm/tumor. Despite this, many<unk> s are found to have clonal chromosomal aberrations that are acquired through somatic mutations, and on this basis the term<unk>  is sometimes considered synonymous with neoplasm.<unk> s are by definition benign, slow-growing or self-limiting, though the underlying condition may still predispose the individual towards malignancies.<unk> s are usually caused by a genetic syndrome that affects the development cycle of all or at least multiple cells. Many of these conditions are classified as overgrowth syndromes or cancer syndromes.<unk> s occur in many different parts of the body and are most often asymptomatic incidentalomas (undetected until they are found incidentally on an imaging study obtained for another reason). Additionally, the definition of<unk>  versus benign neoplasm is often unclear, since both lesions can be clonal. Lesions such as adenomas, developmental cysts, hemangiomas, lymphangiomas and rhabdomyomas within the kidneys, lungs or pancreas are interpreted by some experts as<unk> s while others consider them true neoplasms. Moreover, even though<unk> s show a benign histology, there is a risk of some rare but life-threatening complications such as those found in neurofibromatosis type I and tuberous sclerosis. It is different from choristoma, a closely related form of heterotopia. The two can be differentiated as follows: a<unk>  is an excess of normal tissue in a normal situation (e.g., a birthmark on the skin), while a choristoma is an excess of tissue in an abnormal situation (e.g., pancreatic tissue in the duodenum). The term<unk>  is from the Greek ἁμαρτία, hamartia ("error"), and was introduced by D.P.G. Albrecht in 1904.
Hamartoma
Thecoma
Askin's tumor
Lipoblastoma
Cylindroma
Syringoma
Neural fibrolipoma
Luteoma