<unk>  was caused by cadmium poisoning due to mining in Toyama Prefecture. Regular mining for silver started in 1589, and soon thereafter, mining for lead, copper, and zinc began. The earliest records of mining for gold in the area date back to 1710. Cadmium is a metal byproduct of mining that is toxic to most organisms. Recent animal studies have shown that cadmium poisoning alone is not enough to elicit all of the symptoms of<unk> . These studies are pointing to damage of the mitochondria of kidney cells by cadmium as a key factor of the disease.
Itai-itai disease
Bahima disease
Toroku arsenic disease
Vogt–Koyanagi–Harada disease
Wilson's disease
BENTA disease
Leiner's disease
Minamata disease