<unk>  is an orally administered leukotriene receptor antagonist (LTRA) used for the chronic treatment of asthma. While<unk>  is generally well tolerated, headache and stomach upset often occur. Some rare side effects can occur, which can be life-threatening, such as liver failure. Churg-Strauss syndrome has been associated with<unk> , but the relationship isn't thought to be causative in nature. Overdoses of<unk>  tend to be self-limiting.<unk> , like other LTRAs, works by inhibiting the immune system. Through its action on inflammatory cells in the lungs,<unk>  reduces the production of inflammatory mediators that are implicated in the pathogenesis of asthma.<unk>  is extensively hepatically metabolized by an enzyme called CYP2C9.<unk>  inhibits the action of CYP3A4, leading to drug-drug interactions with other drugs that are metabolized by CYP3A4. Genetic differences in LTC4 synthase and CYP2C9 may predict how a person reacts to<unk>  treatment.<unk>  (brand name Accolate) was the first cysteinyl leukotriene receptor antagonist approved in the United States. It is now approved in many other countries under other brand names.
Zafirlukast
Pranlukast
Seratrodast
Montelukast
Levosalbutamol
Salbutamol
Lifitegrast
Pemirolast