<unk>  is a protein synthesis inhibitor in nonresistant cells by binding to 16S ribosomal RNA. This broad-spectrum antibiotic soluble in water, is very similar in action to neomycin. Antimicrobial activity of<unk>  against Escherichia coli and Staphylococcus aureus has been shown.<unk>  works as an antibiotic by increasing the error rate in ribosomal translation.<unk>  binds to a RNA loop, where residues A1492 and A1493 are usually stacked, and expels these two residues. These two residues are involved in detection of correct Watson-Crick pairing between the codon and anti codon. When correct interactions are achieved, the binding provides energy to expel the two residues.<unk>  binding provides enough energy for residue expulsion and thus results in the ribosome incorporating the incorrect amino acid into the nascent peptide chain.
Paromomycin
Capreomycin
Anisomycin
Dactinomycin
Spectinomycin
Natamycin
Clarithromycin
Erythromycin