Treatment for<unk>  relies on managing its symptoms. Children with SMS often require several forms of support, including physical therapy, behaviour therapy, occupational therapy and speech therapy. Support is often required throughout an affected person's lifetime. Medication is often used to address some symptoms. Melatonin supplements and trazodone are commonly used to regulate sleep disturbances. In combination with exogenous melatonin, blockade of endogenous melatonin production during the day by the adrenergic antagonist acebutolol can increase concentration, improve sleep and sleep timing and aid in improvement of behaviour. Other medications (such as risperdal) are sometimes used to regulate violent behavior.
Smith–Magenis syndrome
Marshall–Smith syndrome
Wilson–Turner syndrome
Bardet–Biedl syndrome
Beckwith–Wiedemann syndrome
Smith–Lemli–Opitz syndrome
Kapur–Toriello syndrome
Smith Martin Dodd syndrome