Note that this description is focused on<unk>  of childhood. Similar syndromes may develop following a brainstem infarction. The cause of<unk>  of childhood is the mutation of ATP1A3 gene. In a study of fifteen females and nine males’ patient with<unk> , a mutation in ATP1A3 gene was present. Three patients showed heterozygous de-novo missense mutation. Six patients were found with de-novo missense mutation and one patient was identified with de-novo splice site mutation. De novo mutation is a mutation that occurs in the germ cell of one parent. Neither parent has the mutation, but it is passed to the child through the sperm or egg.
Alternating hemiplegia
Spastic diplegia
Spastic hemiplegia
Triplegia
Harding ataxia
Dissociated sensory loss
Tetraplegia
Paraplegia