The<unk>  codes for a class of structurally related cell surface receptors that fulfill diverse biological functions in different organs, tissues, and cell types. The role that is most commonly associated with this evolutionarily ancient<unk>  is cholesterol homeostasis (maintenance of appropriate concentration of cholesterol). In humans, excess cholesterol in the blood is captured by<unk><unk><unk>  (LDL) and removed by the liver via endocytosis of the LDL receptor. Recent evidence indicates that the members of the LDL receptor<unk><unk>  are active in the cell signalling pathways between specialized cells in many, if not all, multicellular organisms. There are seven members of the LDLR<unk>  in mammals, namely: * LDLR * VLDL receptor (VLDLR) * ApoER2, or LRP8 *<unk><unk><unk>  receptor-related protein 4 * also known as multiple epidermal growth factor (EGF) repeat-containing protein (MEGF7) * LDLR-related protein 1 * LDLR-related protein 1b * Megalin.
Low-density lipoprotein receptor gene family
LDL receptor
VLDL receptor
Heart-type fatty acid binding protein
Tumor-associated glycoprotein 72
Fibroblast growth factor receptor 3
Growth hormone secretagogue receptor
Netrin receptor DCC