<unk>  treatment concerns comfort (relieving pain via analgesics) and rest (via use of mechanisms to make life easier, such as a powered wheelchair) and is generally of palliative care. No reversive therapies are known. Fatigue is usually the most disabling symptom. Energy conservation can significantly reduce fatigue episodes. Such can be achieved by lifestyle changes, such as additional (daytime) sleep, reducing workload, and weight loss for obesity. Some require lower-limb orthotics to reduce energy usage. Medications for fatigue, such as amantadine and pyridostigmine, are ineffective in the management of<unk> . Muscle strength and endurance training are more important in managing the symptoms of<unk>  than the ability to perform enduring aerobic activity. Management should focus on treatments such as hydrotherapy and developing other routines that encourage strength, but do not affect fatigue levels. A recent trend toward use of intravenous immunoglobulin, which had yielded promising albeit modest results, but proves insufficient to recommend as a treatment.<unk>  increasingly stresses the musculoskeletal system from progressive muscular atrophy. In a review of 539<unk>  patients, 80% reported pain in muscles and joints and 87% had fatigue. Joint instability can cause appreciable pain and should be adequately treated with painkillers. Directed activity, such as decreasing mechanical stress with braces and adaptive equipment, is recommended. Because<unk>  can fatigue facial muscles, as well as cause dysphagia (difficulty swallowing), dysarthria (difficulty speaking) or aphonia (inability to produce speech), persons may become malnourished from difficulty eating. Compensatory routines can help relieve these symptoms, such as eating smaller portions at a time and sitting down whilst eating.<unk>  with respiratory involvement requires exceptional therapy management, such as breathing exercises and chest percussion to expel secretions (clearing of the lungs) on a periodic basis (monitored via stethoscope). Failure to properly assess<unk>  with respiratory involvement can increase the risk of overlooking an aspiration pneumonia (a life-threatening infection of the lower respiratory tract, especially so if not caught early on). Severe cases may require permanent ventilation or tracheostomy. Sleep apnoea may also occur. Other management strategies that show improvement include smoking cessation, treatment of other respiratory diseases, and vaccination against respiratory infections such as influenza.
Post-polio syndrome
Leukomyelitis
Guillain–Barré syndrome
FACES syndrome
Acute disseminated encephalomyelitis
Eastern equine encephalitis
Tension myositis syndrome
Postvaccinal encephalitis