Typically,<unk>  disease is diagnosed shortly after birth, although it may develop well into adulthood, because of the presence of megacolon, or because the baby fails to pass the first stool (meconium) within 48 hours of delivery. Normally, 90% of babies pass their first meconium within 24 hours, and 99% within 48 hours. Other symptoms include green or brown vomit, swelling of the abdomen, excessive gas, and bloody diarrhea. Some cases are diagnosed later, into childhood, but usually before age 10. The child may experience fecal retention, constipation, or abdominal distention. Associated syndromes<unk>  can also present as part of multi system disorders, such as: * Bardet–Biedl syndrome * Cartilage–hair hypoplasia * Congenital central hypoventilation syndrome * MEN2 * Mowat–Wilson syndrome * Smith–Lemli–Opitz syndrome * Trisomy 21 (Down syndrome) * Some forms of Waardenburg syndrome
Hirschsprung's disease
Meconium
Retained antrum syndrome
Intestinal pseudo-obstruction
Hartnup disease
Necrotizing enterocolitis
Meckel's diverticulum
Intestinal malrotation