<unk>  is a glucocorticoid for systemic use. Substitution at position 16 also leads to more potent corticosteroids. The additional steric bulk introduced by such substituents adjacent to the dihydroxyacetone side chain also protects that moiety against metabolic degradation.
Prednylidene
Dicycloverine
Avacopan
Diphenhydramine
Buffalopox
Allergan
Dihydroergotamine
Crotamiton