Organ transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with<unk>  was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with<unk>  than with ciclosporin during the first year of liver transplantation. Long-term outcome has not been improved to the same extent.<unk>  is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate, and IL-2 receptor inhibitors such as basiliximab. Dosages are titrated to target blood levels at specific times after medication administration. Skin<unk>  0.1% Ointment As an ointment,<unk>  is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of<unk>  is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side effects. It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
Tacrolimus
Sirolimus
Temsirolimus
Pimecrolimus
Ruxolitinib
Rituximab
Tofacitinib
Ropeginterferon alfa-2b