The main components in the<unk>  system include intervertebral disks, joints, bones, nervous and muscular system. The deterioration of<unk>  components leads to symptoms such as pain, limitation in joint mobility, malalignment, balance disorder and gait abnormality. Syndrome progression leads to reduced ability to perform activities of daily living independently and eventually results in decreased quality of life and necessity of nursing care. People with<unk>  may not be able to accomplish everyday tasks such as putting socks on while standing on one leg, doing moderately intensive house chores, carrying home 5 pounds of shopping and walking nonstop for 15 minutes. They may also slip around or trip up the house and need to hold on to handrails for support whilst climbing up the stairs. Degenerative changes in the main components of the<unk>  system begin before middle age. Generally in the initial stages, the progression is slow and asymptomatic. The symptoms only become obvious when pathological degeneration changes become advanced.
Locomotive syndrome
Winter-over syndrome
Central pain syndrome
Narcissism
Sympathicolysis
Hard flaccid syndrome
DOOR syndrome
Stiff skin syndrome