Risks and complications in<unk>  are similar to those associated with all joint replacements. The most serious complication is infection of the joint, which occurs in 30mm/hr) and serum C-reactive protein (CRP>10 mg/L) concentration, 2.Elevated synovial leukocyte count, 3.Elevated synovial neutrophil percentage (PMN%), 4.Presence of purulence in the affected joint, 5.Isolation of a microorganism in one culture of periprosthetic tissue or fluid, or 6. Greater than five neutrophils per high-power field in five high-power fields observed from histologic analysis of periprosthetic tissue at ×400 magnification. None of the above laboratory tests has 100% sensitivity or specificity for diagnosing infection. Specificity improves when the tests are performed in patients in whom clinical suspicion exists. ESR and CRP remain good 1st line tests for screening (high sensitivity, low specificity). Aspiration of the joint remains the test with the highest specificity for confirming infection. The choice of treatment depends on the type of prosthetic infection. # Positive intraoperative cultures: Antibiotic therapy alone # Early post-operative infections: debridement, antibiotics, and retention of prosthesis. # Acute hematogenous infections: debridement, antibiotic therapy, retention of prosthesis. # Late chronic: delayed exchange arthroplasty. Surgical débridement and parenteral antibiotics alone in this group has limited success, and standard of care involves exchange arthroplasty. Appropriate antibiotic doses can be found at the following instructional course lecture by AAOS
Knee replacement
Joint replacement
Ankle replacement
Unicompartmental knee arthroplasty
Finger joint replacement
Shoulder replacement
Hip replacement
Arthroplasty