<unk>  plays a key role in pyrimidine salvage to recover nucleosides after DNA/RNA degradation. Although the reaction it catalyzes between<unk> /deoxyuridine and their respective bases is reversible, the enzyme's function is primarily catabolic. Recent research has found that<unk>  is also involved in angiogenesis. Experiments show inhibition of angiogenic effect by<unk>  in the presence of 6-amino-5-chlorouracil, an inhibitor of<unk> , suggesting that the enzymatic activity of<unk>  is required for its angiogenic activity.<unk>  has been determined to be almost identical to the platelet-derived endothelial cell growth factor (PD-ECGF). Although the mechanism of angiogenesis by<unk>  is not yet known, reports show that the enzyme itself is not a growth factor but indirectly causes angiogenesis by stimulating chemotaxis of endothelial and other cells. Some reports suggest that<unk>  promotes endothelial cell growth by reducing levels of<unk>  that would otherwise inhibit endothelial cell growth. An alternative explanation is that the enzyme’s products induce angiogenesis. Experiments have found that 2-deoxyribose is an endothelial-cell chemoattractant and angiogenesis-inducing factor, which supports this explanation. Research has found<unk>  is involved in angiogenesis during the menstrual cycle. The enzyme's expression in the endometrium is raised by a combination of progesterone and transforming growth factor-β1 and varies over the course of the menstrual cycle.
Thymidine phosphorylase
Xanthine oxidase
Asparaginase
Galactose-1-phosphate uridylyltransferase
Dispase
Iduronate-2-sulfatase
Transaminase
Biotinidase