The neoplastic cells in<unk>  show a monotonous appearance, with a small amount of cytoplasm and inconspicuous nucleoli. Laboratory findings The constellation of thrombocytopenia, anemia, and leukopenia is common in patients with<unk> . Spleen and liver The disease shows a distinct sinusoidal pattern of infiltration which spares the splenic white pulp and hepatic portal triads. Bone marrow While the bone marrow is commonly involved, the detection of the neoplastic infiltrate may be difficult due to a diffuse, interstitial pattern. Immunohistochemistry can aid in diagnosis. Peripheral blood Cells of a similar morphology observed in solid organs are observed in peripheral blood. Immunophenotype The immunophenotype for<unk>  is a post-thymic, immature T-cell. Status Antigens Positive CD3, TCRδ1, TIA-1 Negative CD4, CD5, CD8 Genetic findings Clonal rearrangement of the γ gene of the T-cell receptor is the hallmark of<unk> . A few cases have shown rearrangement of the T-cell receptor β gene. Isochromosome 7q has been observed in all cases described so far, sometimes in conjunction with other chromosomal abnormalities such as trisomy 8.
Hepatosplenic T-cell lymphoma
Splenic marginal zone lymphoma
Splenic lymphoma with villous lymphocytes
AIDS-related lymphoma
Monomorphic epitheliotropic intestinal T cell lymphoma
Amoebic liver abscess
Nodal marginal zone B cell lymphoma
Acinar cell carcinoma of the pancreas