The first-line therapy is symptomatic relief with second-generation H1-antihistamines. If standard dosing is ineffective, increasing dosages up to fourfold is recommended to control symptoms. The second-generation H1-antihistamine rupatadine was found to significantly reduce the development of chronic<unk>  symptom without an increase in adverse effects at doses of and . Allergy medications containing antihistamines such as diphenhydramine (Benadryl), cetirizine (Zyrtec), loratadine (Claritin), cyproheptadine (Periactin), and fexofenadine (Allegra) may be taken orally to prevent and relieve some of the hives. For those who have severe anaphylactic reactions, a prescribed medicine such as doxepin, taken daily, should help to prevent and/or lessen the likelihood of a reaction and thus, anaphylaxis. The effectiveness of topical antihistamine creams against hives induced by<unk>  temperature has not been evaluated.<unk>  hives can result in a potentially serious or even fatal systemic reaction (anaphylactic shock). People with<unk>  hives may have to carry an injectable form of epinephrine (like Epi-pen or Twinject) for use in the event of a serious reaction. The best treatment for this allergy is avoiding exposure to<unk>  temperature. Studies have found that omalizumab (Xolair) may be an effective and safe treatment for<unk>  in patients who do not sufficiently respond to standard treatments. Ebastine has been proposed as an approach to prevent acquired<unk> .
Cold urticaria
Heat urticaria
Solar urticaria
Pressure urticaria
Aquagenic urticaria
Physical urticaria
Cholinergic urticaria
Delayed pressure urticaria