Globally, less than 1 in 100,000 people have HIDS, and of these, ~200 individuals suffer from MKD. This categorises the condition as a rare genetic disease.
Mevalonate kinase deficiency
Guanidinoacetate methyltransferase deficiency
Aminoacylase 1 deficiency
2,4 Dienoyl-CoA reductase deficiency
Triosephosphate isomerase deficiency
Malonyl-CoA decarboxylase deficiency
Holocarboxylase synthetase deficiency
Carbamoyl phosphate synthetase I deficiency