CHG is ototoxic; if put into an ear canal which has a ruptured eardrum, it can lead to deafness. CHG does not meet current European specifications for a hand disinfectant. Under the test conditions of the European Standard EN 1499, no significant difference in the efficacy was found between a 4% solution of<unk>  digluconate and soap. In the U.S., between 2007 and 2009, Hunter Holmes McGuire Veterans Administration Medical Center conducted a cluster-randomized trial and concluded that daily bathing of patients in intensive care units with washcloths saturated with<unk>  gluconate reduced the risk of hospital-acquired infections. Whether prolonged exposure over many years may have carcinogenic potential is still not clear. The US Food and Drug Administration recommendation is to limit the use of a<unk>  gluconate mouthwash to a maximum of six months. When ingested, CHG is poorly absorbed in the gastrointestinal tract and can cause stomach irritation or nausea. If aspirated into the lungs at high enough concentration, as reported in one case, it can be fatal due to the high risk of acute respiratory distress syndrome.
Chlorhexidine
Tolmetin
Sodium hypochlorite
Sodium hydroxide
Amylmetacresol
Lisocabtagene maraleucel
Palifermin
Chloroethane