Synthesis Various routes exist for the synthesis of<unk> s ;Esterification of phosphoric acid :OP(OH)3 + ROH →<unk> (OH)2(OR) + H2O :OP(OH)2(OR) + R'OH →<unk> (OH)(OR)(OR') + H2O :OP(OH)(OR)(OR') + R"OH →<unk> (OR)(OR')(OR") + H2O Alcohols can be detached from phosphate esters by hydrolysis, which is the reverse of the above reactions. For this reason, phosphate esters are common carriers of organic groups in biosynthesis. ;Oxidation of phosphite esters<unk> s can be readily oxidised to give<unk> s :P(OR)3 + O →<unk> (OR)3 ; Alcoholysis of POCl3 Phosphorus oxychloride reacts readily with alcohols to give<unk> s :O=PCl3 + 3 ROH → O=P(OR)3 + 3 HCl Properties The phosphate esters bearing OH groups are acidic and partially deprotonated in aqueous solution. For example, DNA and RNA are polymers of the type Polyphosphates also form esters; an important example of an ester of a polyphosphate is ATP, which is the monoester of triphosphoric acid (H5P3O10).<unk> Es have a central phosphate molecular group. In the case of<unk>  <unk>  triesters, these are three ester bonds with alkyl or aromatic substituents. However,<unk>  diesters are different from the triesters as one of the alkyl ester groups is replaced by a hydroxyl group, making<unk>  diesters phosphoric acids. The wide variety of substitutes used in<unk>  esters results in great variations in physicochemical properties, varying from highly polar to very hydrolysis resistant characteristics.<unk> Es exhibit a wide range of octanol water partitioning coefficient where log Kow values range from -0.98 up to 10.6. The predominant<unk> Es used as flame retardants and plasticizers have a positive log Kow values ranging between 1.44 and 9.49 signifying hydrophobicity. Thus, owing to this hydrophobicity<unk> Es are presumptively bioaccumulated and biomagnified in aquatic ecosystems. Laboratory experiments had shown that the non-halogenated<unk> Es are prone to photolysis, while the chlorinated<unk> Es such as TCEP and TCPP, however, seemed to be resistant to degradation by sunlight.
Organophosphate
Loline alkaloid
Antacid
Querulant
Detergent
Polychlorinated naphthalene
Alcohol 
Alkylphenol