<unk>  is an irreversible mechanism-based inhibitor of gamma-aminobutyric acid aminotransferase (GABA-AT), the enzyme responsible for the catabolism of GABA. Inhibition of GABA-AT results in increased levels of GABA in the brain.<unk>  is a racemic compound, and its S-enantiomer is pharmacologically active., Crystal Structure (pdb:1OHW) showing<unk>  binding to specific residues in the active site of GABA-AT, based on experiments by Storici et al.
Vigabatrin
Mitapivat
Stiripentol
Bocasan
Tasimelteon
Fosaprepitant
Influenzanet
Veristrat