<unk>  cell: pleomorphic abnormal T cell with the characteristic cerebriform nuclei (Peripheral blood - MGG stain).<unk>  and mycosis fungoides are cutaneous T-cell lymphomas having a primary manifestation in the skin. The disease's origin is a peripheral CD4+ T-lymphocyte, although rarer CD8+/CD4- cases have been observed. Epidermotropism (lymphocytes residing in the epidermis) by neoplastic CD4+ lymphocytes with the formation of Pautrier's microabscesses is the hallmark sign of the disease. Although the condition can affect people of all ages, it is commonly diagnosed in adults over age 60. The dominant signs and symptoms of the disease are: # Generalized erythroderma– redness of the skin # Lymphadenopathy – swollen, enlarged lymph nodes # Atypical T-cells – malignant lymphocytes known as<unk>  cells" seen in the peripheral blood with typical cerebriform nuclei (brain-shaped, convoluted nuclei) # Hepatosplenomegaly– enlarged liver and spleen # Palmoplantar keratoderma – thickening of the palms of the hands, and soles of the feet
Sézary disease
Degos disease
Fox–Fordyce disease
Ollier disease
Chandler's disease
Akureyri disease
Johnson–McMillin syndrome
Bayoud disease