Cytogenetics * Alterations of chromosome 3p segments occurs in 70 – 90% of<unk> s * Inactivation of von Hippel-Lindau disease (VHL) gene by gene mutation and promoter hypermethylation * Gain of chromosome 5q * Loss of chromosomes 8p, 9p, and 14q Molecular genetics Several frequently mutated genes were discovered in<unk> : VHL, KDM6A/UTX, SETD2, KDM5C/JARID1C and MLL2. PBRM1 is also commonly mutated in<unk> .
Clear cell renal cell carcinoma
Renal medullary carcinoma
Renal anaplastic sarcoma
Papillary renal cell carcinoma
Renal medullary fibroma
Clear cell papillary renal cell carcinoma
Renal oncocytoma
Renal cell carcinoma