Estradiol, the major estrogen sex hormone in humans<unk><unk>  can disrupt the normal human homeostasis and result in abnormal estrogen levels. For example,<unk><unk>  can cause different physiological effects in males and females. In particular, estrogen studies have revealed complex interactions with<unk><unk> . Estrogen was initially proposed to be a possible treatment for certain types of<unk><unk>  but a plethora of harmful side effects such as increased susceptibility to breast cancer and coronary heart<unk> overshadowed any beneficial outcomes. On the other hand, Estrogen Replacement Therapy has shown some positive effects with postmenopausal women. Estrogen and estrogen-like molecules form a large family of potentially beneficial alternatives that can have dramatic effects on human homeostasis and<unk>  Subsequently, large-scale efforts were initiated to screen for useful estrogen family molecules. Furthermore, scientists discovered new ways to synthesize estrogen-like compounds that can avoid many side effects.
Estrogen and neurodegenerative diseases
Obesity and fertility
Estrogenic substances
Diet and cancer
Prostate Adenocarcinoma: TransCutaneous Hormones
Menopause, Estrogen and Venous Events
Age and female fertility
Hormone-sensitive cancer