Subunit vaccines contain parts of the virus selected to stimulate an immune response, without including the entire virus. Because the fragments are incapable of causing disease, subunit vaccines are considered very safe. Subunit vaccines in widespread use include the Hepatitis B vaccine and Pertussis vaccine.<unk>  has a trimeric form of the SARS-CoV-2 spike protein (S-Trimer) combined with one of two different adjuvants AS03 (GlaxoSmithKline) or CpG/Alum (Dynavax). The vaccine displays the spike protein in its natural three-part form, leading to a potentially better immune response. The vaccine is similar to other subunit COVID-19 vaccines including Novavax, Abdala, and ZF2001. The vaccine is stable for at least six months under normal refrigeration conditions and at least one month at 40 degrees Celsius.
SCB-2019
HPTN 052
TIME-ITEM
DCAP-BTLS
SWAP-200
STAR*D
COMLEX-USA
WebPT