Mechanism of action<unk>  is a glucocorticoid that is about five times as potent as cortisol, but has very little mineralocorticoid effects. Pharmacokinetics When taken by mouth, the drug's bioavailability is over 90%. It reaches highest concentrations in the blood plasma after one to two hours and is bound to plasma proteins to about 80%. The biological half-life from the plasma is 200 to 300 minutes; due to stable complexes of<unk>  and its receptor in the intracellular fluid, the total half-life is significantly longer at about 36 hours. A small fraction of the substance is metabolized to 6-hydroxy- and 20-dihydro-triamcinolone; most of it probably undergoes glucuronidation, and a smaller part sulfation. Three quarters are excreted via the urine, and the rest via the faeces. Due to corticoids' mechanism of action, the effects are delayed as compared to plasma concentrations. Depending on the route of administration and the<unk> eated condition, the onset of action can be from two hours up to one or two days after application; and the drug can act much longer than its elimination half-life would suggest.
Triamcinolone
Ciclesonide
Fluocinonide
Amcinonide
Fluocinolone acetonide
Flumedroxone acetate
Prednisone
Mometasone