<unk>  also be classified as 2 categories, melanocytic or non-melanocytic. (Melanocytic being the genesis due to the increase in melanotic pigments and non-melanocytic origin being the genesis from non melanotic causes). The prevalence of melanocytic and non-melanocytic causes of<unk>  melanosis was roughly 1:1. Physiological<unk>  affects about 3% of the population and is most likely seen in those with dark skin Peutz Jeghers syndrome For Peutz Jeghers syndrome the frequency is approximately 1 case per 60,000-300,000 people in the USA. Equal occurrence in both sexes and all races. Average age of diagnosis being 23 years in men and 26 years in women. Smokers melanosis Smoker’s melanosis is present in all age groups, has no observed sex or race predilection. Melanotic macule For hyperplastic or neoplastic processes, the mean age of<unk>  melanotic macule (hyperplastic- increase in malanoticpigments without an increase in malanocytes) is 43.1 years with the mean size of the lesion was about 6.8mm. The female: male ratio is 2:1 and lower lip being the most common location. For<unk>  melanoma (neoplastic) the mean age was 53.8 years with equal ratio of female:male and most common location being in the palate or gingiva.<unk>  melanoma For<unk>  melanoma (neoplastic lesion), the mean age was 53.8 years with equal ratio of female:male and most common location being in the palate or gingiva. Cumulative frequency The occurrence of<unk>  malanosis on the cheeks were (21%), alveolar mucosa (16.6%), gingiva (11.8%). Amalgam tattoo being majority of the cases (46.3%), malanotic macules (22.9%) and nevus (20.5%).
Oral pigmentation
Nipple pigmentation
Breast hypertrophy
Hypopigmentation
Trichomegaly
Blue nails
Tooth discoloration
Green nails