Large<unk><unk> , is a structural deformity of the inner ear.<unk> ent of this duct is one of the most common inner ear deformities and is commonly associated with hearing loss during childhood. The term was first discovered in 1791 by Mondini when he was completing a temporal bone dissection. It was then defined by Valvassori and Clemis as a<unk><unk>  that is greater than or equal to 2.0 mm at the operculum and/or greater than or equal to 1.0 mm at the midpoint. Some use the term<unk>  syndrome but this is felt by others to be erroneous as it is a clinical finding which can occur in several syndromes.
Enlarged vestibular aqueduct
Vitreous bulge
Pellucid marginal degeneration
Optokinetic drum
Optic nerve hypoplasia
Vitreomacular adhesion
Posterior cortical atrophy
Persistent pupillary membrane