The enzymes do not reach the bloodstream in significant amounts and are presumed to largely stay at the point of injection until they are broken down by proteases. The two<unk> s act synergistically by cleaving tropocollagen (the 'collagen molecule') at different points. AUX-I attacks the C- and N-termini, AUX-II cleaves amino acid bonds within the molecule. Small collagen fragments are broken down by both enzymes.
Collagenase clostridium histolyticum
Fusobacteriota
Helicobacter heilmannii sensu lato
Lactase
Bacillus cereus biovar anthracis
Candidalysin
Helicobacter heilmannii s.s
Staphylococcus saprophyticus