Differential diagnosis Differentiating<unk>  from other neurological disorders can be very difficult. It requires expert judgement to separate symptoms of<unk>  from other diseases. Some of the most commonly mistaken diseases are encephalitis, toxic encephalopathy, status epilepticus, heat stroke, catatonia and malignant hyperthermia. Due to the comparative rarity of<unk> , it is often overlooked and immediate treatment for the syndrome is delayed. Drugs such as cocaine and amphetamine may also produce similar symptoms. The differential diagnosis is similar to that of hyperthermia, and includes serotonin syndrome. Features which distinguish<unk>  from serotonin syndrome include bradykinesia, muscle rigidity, and a high white blood cell count.
Neuroleptic malignant syndrome
Malignant hyperthermia
Limbic encephalitis
Catatonia
Viral encephalitis
Serotonin syndrome
Oculogyric crisis
Heat stroke