<unk>  sensations range from pain or an aching in the muscles, to "an itch you can't scratch", a "buzzing sensation", an unpleasant "tickle that won't stop", a "crawling" feeling, or limbs jerking while awake. The sensations typically begin or intensify during quiet wakefulness, such as when relaxing, reading, studying, or trying to sleep. It is a "spectrum" disease with some people experiencing only a minor annoyance and others having major disruption of sleep and impairments in quality of life. The sensations—and the need to move—may return immediately after ceasing movement or at a later time.<unk>  may start at any age, including childhood, and is a progressive disease for some, while the symptoms may remit in others. In a survey among members of the<unk>  Foundation, it was found that up to 45% of patients had their first symptoms before the age of 20 years. * "An urge to move, usually due to uncomfortable sensations that occur primarily in the<unk> , but occasionally in the arms or elsewhere." :The sensations are unusual and unlike other common sensations. Those with<unk>  have a hard time describing them, using words or phrases such as uncomfortable, painful, 'antsy', electrical, creeping, itching, pins and needles, pulling, crawling, buzzing, and numbness. It is sometimes described similar to a limb 'falling asleep' or an exaggerated sense of positional awareness of the affected area. The sensation and the urge can occur in any body part; the most cited location is<unk> , followed by arms. Some people have little or no sensation, yet still, have a strong urge to move. * "Motor<unk> ness, expressed as activity, which relieves the urge to move." :Movement usually brings immediate relief, although temporary and partial. Walking is most common; however, stretching, yoga, biking, or other physical activity may relieve the symptoms. Continuous, fast up-and-down movements of the leg, and/or rapidly moving the<unk>  toward then away from each other, may keep sensations at bay without having to walk. Specific movements may be unique to each person. * "Worsening of symptoms by relaxation." :Sitting or lying down (reading, plane ride, watching TV) can trigger the sensations and urge to move. Severity depends on the severity of the person's<unk> , the degree of restfulness, duration of the inactivity, etc. * "Variability over the course of the day-night cycle, with symptoms worse in the evening and early in the night." :Some experience<unk>  only at bedtime, while others experience it throughout the day and night. Most people experience the worst symptoms in the evening and the least in the morning. *<unk> <unk>  feel similar to the urge to yawn, situated in the<unk>  or arms." :These symptoms of<unk>  can make sleeping difficult for many patients and a recent poll shows the presence of significant daytime difficulties resulting from this condition. These problems range from being late for work to missing work or events because of drowsiness. Patients with<unk>  who responded reported driving while drowsy more than patients without<unk> . These daytime difficulties can translate into safety, social and economic issues for the patient and for society.<unk>  may contribute to higher rates of depression and anxiety disorders in<unk>  patients. Primary and secondary<unk>  is categorized as either primary or secondary. * Primary<unk>  is considered idiopathic or with no known cause. Primary<unk>  usually begins slowly, before approximately 40–45 years of age and may disappear for months or even years. It is often progressive and gets worse with age.<unk>  in children is often misdiagnosed as growing pains. * Secondary<unk>  often has a sudden onset after age 40, and may be daily from the beginning. It is most associated with specific medical conditions or the use of certain drugs (see below).
Restless legs syndrome
Akathisia
Parkinsonism
Insomnia
Cancer-related fatigue
Gigantism
Bruxism
Lonomia