<unk>  is a rare systemic infectious disease caused by the bacterium Tropheryma<unk> i. First described by George Hoyt<unk>  in 1907 and commonly considered as a gastrointestinal disorder,<unk>  primarily causes malabsorption, but may affect any part of the human body, including the heart, brain, joints, skin, lungs and the eyes. Weight loss, diarrhea, joint pain, and arthritis are common presenting symptoms, but the presentation can be highly variable in certain individuals, and about 15% of patients do not have the standard signs and symptoms.<unk>  is significantly more common in men, with 87% of patients diagnosed being male. When recognized and treated,<unk>  can usually be cured with long-term antibiotic therapy, but if the disease is left undiagnosed or untreated, it can ultimately be fatal.
Whipple's disease
Anti-Hu associated encephalitis
Riga–Fede disease
Hereditary pancreatitis
Kimura's disease
Pellegrini–Stieda syndrome
Dukes' disease
Duodenal cancer