The medical uses of<unk>  are the same as those of estradiol and other estrogens.<unk>  is used in hormone therapy for the treatment of menopausal symptoms such as hot flashes and vaginal atrophy and in the treatment of hypoestrogenism and delayed puberty due to hypogonadism or other causes in women. It is also used in feminizing hormone therapy for transgender women. Aside from hormone therapy,<unk>  is used in the treatment of gynecological disorders such as menstrual disorders, dysfunctional uterine bleeding, and breast engorgement. In addition, it is used as a form of high-dose estrogen therapy in the palliative treatment of prostate cancer in men.<unk>  has typically been used at a dosage of 1 to 5 mg once or twice per week by intramuscular injection for relevant indications. It has been used in the treatment of menopausal symptoms at a dosage of 1 to 5 mg initially for two to three injections and 1 to 2.5 mg for maintenance once every 10 to 14 days, and in the treatment of hypoestrogenism and delayed puberty at a dosage of 2.5 to 5 mg once per week. As a component of feminizing hormone therapy for transgender women,<unk>  has been used at dosages of 2 to 10 mg once per week or 5 to 20 mg once every 2 weeks. In the treatment of prostate cancer,<unk>  has been used at a dosage of 5 mg once per week. Available forms<unk>  was previously available by itself as an oil solution for intramuscular injection provided as vials and ampoules at concentrations of 0.1, 0.2, 0.5, 1, 2.5, and 5 mg/mL. The medication has largely been discontinued, with most of these formulations no longer being available.<unk>  remains available at a concentration of 1 mg/mL in combination with 50 mg/mL hydroxyprogesterone caproate under the brand name EP Hormone Depot (Teikoku Zoki Pharmaceutical Company) in Japan.
Estradiol dipropionate
Estradiol furoate
Estradiol undecylate
Estradiol hemisuccinate
Estradiol valerate
Estradiol dienantate
Estradiol enantate
Estradiol diundecylenate