<unk>  are a class of drugs that inhibit the mechanistic target of rapamycin <unk> , which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases (PIKKs).<unk>  regulates cellular metabolism, growth, and proliferation by forming and signaling through two protein complexes,<unk> C1 and<unk> C2. The most established<unk>  are so-called rapalogs (rapamycin and its analogs), which have shown tumor responses in clinical trials against various tumor types.
MTOR inhibitors
Reuptake inhibitor
COX-2 inhibitor
GABA analogue
CDK inhibitor
RET inhibitor
C-Met inhibitor
Targeted covalent inhibitors