A radiography during an intervention of deep brain stimulation It is very difficult to treat an<unk> . The<unk>  may disappear for a while after a treatment has been administered and then return. This situation is addressed with a different treatment. First, individuals will be asked if they use any of the drugs known to cause<unk> s. If so, they are asked to stop taking the medication and then evaluated after some time to determine if the medication was related to the onset of the<unk> . If the<unk>  persists, treatment that follows may include drug therapy, lifestyle changes, and more invasive forms of treatment, such as surgery and thalamic deep brain stimulation.<unk> s are known to be very difficult to treat with pharmacotherapy and drugs. Although there is no established pharmacological treatment for an<unk> , several drugs have been found to have positive effects on<unk> s and are used as treatment by many health professionals. Isoniazid, buspirone hydrochloride, glutethimide, carbamazepine, clonazepam, topiramate, zofran, propranolol and primidone have all seen moderate results in treating<unk>  and can be prescribed treatments. Isoniazid inhibits γ-aminobutyric acid-aminotransferase, which the first step in enzymatic breakdown of GABA, thus increasing GABA, the major inhibitory neurotransmitter in the central nervous system. This causes a reduction in cerebellar ataxias. Another neurotransmitter targeted by drugs that has been found to alleviate<unk> s is serotonin. The agonist buspirone hydrochloride, which decreases serotonin's function in the central nervous system, has been viewed as an effective treatment of<unk> s. Physical therapy has had great results in reducing<unk> s but usually does not cure them. Relaxation techniques, such as meditation, yoga, hypnosis, and biofeedback, have seen some results with<unk> s. Wearing wrist weights which weigh down one's hands as they make movements, masking much of the<unk> , is a proven home remedy. This is not a treatment, since wearing the weights does not have any lasting effects when they are not on. However, they do help the individual cope with the<unk>  immediately. A more radical treatment that is used in individuals who do not respond to drug therapy, physical therapy, or any other treatment listed above, with moderate to severe<unk> s, is surgical intervention. Deep brain stimulation and surgical lesioning of the thalamic nuclei has been found to be an effective long-term treatment with<unk> s. Deep brain stimulation treats<unk> s but does not help related diseases or disorders such as dyssynergia and dysmetria. Deep brain stimulation involves the implantation of a device called a neurostimulator, sometimes called a 'brain pacemaker'. It sends electrical impulses to specific parts of the brain, changing brain activity in a controlled manner. In the case of an<unk> , the thalamic nuclei is the region targeted for treatment. This form of treatment causes reversible changes and does not cause any permanent lesions. Since it is reversible, deep brain stimulation is considered fairly safe: Reduction in<unk>  amplitude is almost guaranteed and sometimes resolved. Some individuals with multiple sclerosis have seen sustained benefits in MS progress. Thalamotomy is another surgical treatment where lesions of the thalamus nucleus are created to disrupt the<unk>  circuit. Thalamotomy has been used to treat many forms of<unk> s, including those that arise from trauma, multiple sclerosis, stroke, and those whose cause it unknown. This is a very invasive, high-risk treatment with many negative effects, such as multiple sclerosis worsening, cognitive dysfunction, worsening of dysarthria, and dysphagia. Immediate positive effects are seen in individuals treated with a thalamotomy procedure. However, the<unk>  often comes back; it is not a complete treatment. Thalamotomy is in clinical trials to determine the validity of the treatment of<unk> s with all its high risks.
Intention tremor
Essential tremor
Holmes tremor
Scissor gait
Misophonia
Dyskinesia
Abnormal posturing
Myopathic gait