<unk>  is an intermediate-acting benzodiazepine of the 3-hydroxy family; it acts on benzodiazepine receptors, resulting in increased effect of GABA to the GABAA receptor which results in inhibitory effects on the central nervous system. The half-life of<unk>  is between 6 and 9 hours. It has been shown to suppress cortisol levels.<unk>  is the most slowly absorbed and has the slowest onset of action of all the common benzodiazepines according to one British study.<unk>  is an active metabolite formed during the breakdown of diazepam, nordazepam, and certain similar drugs. It may be safer than many other benzodiazepines in patients with impaired liver function because it does not require hepatic<unk> idation, but rather, it is simply metabolized by glucuronidation, so<unk>  is less likely to accumulate and cause adverse reactions in the elderly or people with liver disease.<unk>  is similar to lorazepam in this respect. Preferential storage of<unk>  occurs in some organs, including the heart of the neonate. Absorption by any administered route and the risk of accumulation is significantly increased in the neonate, and withdrawal of<unk>  during pregnancy and breast feeding is recommended, as<unk>  is excreted in breast milk. 2 mg of<unk>  equates to 1 mg of diazepam according to the benzodiazepine equivalency converter, therefore 20 mg of<unk>  according to BZD equivalency equates to 10 mg of diazepam and 15 mg<unk>  to 7.5 mg diazepam (rounded up to 8 mg of diazepam). Some BZD equivalency converters use 3 to 1<unk>  to diazepam), 1 to 3 (diazepam to<unk>  as the ratio (3:1 and 1:3), so 15 mg of<unk>  would equate to 5 mg of diazepam.
Oxazepam
Halazepam
Quazepam
Bromazepam
Triazolam
Medazepam
Diclazepam
Cinolazepam