<unk><unk> s are synthetically modeled after the natural<unk> decapeptide with specific modifications, usually double and single substitutions and typically in position 6 (amino acid substitution), 9 (alkylation) and 10 (deletion). These substitutions inhibit rapid degradation.<unk> s with two substitutions include: leuprorelin, buserelin, histrelin, goserelin, and deslorelin. The agents nafarelin and triptorelin are<unk> s with single substitutions at position 6.
Gonadotropin-releasing hormone agonist
Gonadotropin-releasing hormone antagonist
Gonadotropin-releasing hormone modulator
Prolactin modulator
Antiandrogen
Thyroid blocker
17α-Alkylated anabolic steroid
Steroidal antiandrogen