<unk> , or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking,<unk>  is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.<unk>  is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes<unk>  a member of the immunoglobulin superfamily.<unk>  functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that<unk>  blockade restores homeostatic microglial phagocytosis in aging brains. image of microglia
CD22
CD74
CD23
CD80
CD86
CD4
CDV3 
CD8