Fatigue is a normal result of work, mental stress, anxiety, overstimulation and understimulation, jet lag, active recreation, boredom, lack of sleep or disease. Acute Causes of acute fatigue include depression; chemical causes, such as dehydration, poisoning, low blood sugar, or mineral or vitamin deficiencies. Fatigue is different from drowsiness, where a patient feels that sleep is required. Temporary fatigue is likely to be a minor illness like the common cold as one part of the sickness behavior response that happens when the immune system fights an infection. Prolonged Prolonged fatigue is a self-reported, persistent (constant) fatigue lasting at least one month. Chronic Chronic fatigue is a self-reported fatigue lasting at least six consecutive months. Chronic fatigue may be either persistent or relapsing. Chronic fatigue is a symptom of many diseases and conditions. Some major categories of conditions that feature fatigue include: * Autoimmune diseases, such as celiac disease, lupus, multiple sclerosis, myasthenia gravis, Sjögren's syndrome, and spondyloarthropathy * Anxiety disorders such as generalized anxiety disorder * Blood disorders such as anemia and hemochromatosis * Cancer, in which case it is called cancer fatigue * Chronic fatigue syndrome (CFS) * Substance use disorders including alcohol use disorder * Depression and other mental disorders that feature depressed mood * Developmental disorders such as autism spectrum disorder * Eating disorders, which can produce fatigue due to inadequate nutrition * Endocrine diseases or metabolic disorders: diabetes mellitus, hypothyroidism and Addison’s disease * Fibromyalgia * Gulf War syndrome * Heart failure * HIV * Idiopathic chronic fatigue (ICF), which is chronic fatigue with no known cause that does not meet chronic fatigue syndrome criteria * Inborn errors of metabolism such as fructose malabsorption. * Infectious diseases such as infectious mononucleosis or tuberculosis * Irritable bowel syndrome * Kidney diseases e.g. acute renal failure, chronic renal failure * Leukemia or lymphoma * Liver failure or liver diseases e.g. Hepatitis * Lyme disease * Neurological disorders such as narcolepsy, Parkinson's disease, Postural Orthostatic Tachycardia Syndrome and post-concussion syndrome * Physical trauma and other pain-causing conditions, such as arthritis * Sleep deprivation or sleep disorders, e.g. sleep apnea * Stroke * Thyroid disease such as hypothyroidism Fatigue may also be a side effect of certain medications (e.g., lithium salts, ciprofloxacin); beta blockers, which can induce exercise intolerance; and many cancer treatments, particularly chemotherapy and radiotherapy. Inflammation Inflammation has been linked to many types of fatigue. Findings implicate neuroinflammation in the etiology of fatigue in autoimmune and related disorders.
symptom of Botulism
symptom of Narcolepsy
symptom of Alcohol intoxication
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symptom of Panic attack
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symptom of Fasciolosis