Deaths due to<unk>  anemia per million persons in 2012 Disability-adjusted life year for<unk>  anemia per 100,000 inhabitants in 2004 Symptoms of<unk>  can occur even before the condition has progressed to<unk>  anemia. Symptoms of<unk>  are not unique to<unk>  (i.e. not pathognomonic).<unk>  is needed for many enzymes to function normally, so a wide range of symptoms may eventually emerge, either as the secondary result of the anemia, or as other primary results of<unk> . Symptoms of<unk>  include: * fatigue * dizziness/lightheadedness * pallor * hair loss * twitches * irritability * weakness * pica * brittle or grooved nails * hair thinning * Plummer–Vinson syndrome: painful atrophy of the mucous membrane covering the tongue, the pharynx and the esophagus * impaired immune function * pagophagia * restless legs syndrome Continued<unk>  may progress to anemia and worsening fatigue. Thrombocytosis, or an elevated platelet count, can also result. A lack of sufficient<unk>  levels in the blood is one reason that some people cannot donate blood. Signs and symptoms in children * pale skin * fatigue * slowed growth and development * poor appetite * behavioral problems * abnormal rapid breathing * frequent infection<unk>  requirements in young children to teenagers Age group Recommended amount of<unk>  a day 7–12 months 11 mg 1–3 years 7 mg 4–8 years 10 mg 9–13 years 8 mg 14–18 years, girls 15 mg 14–18 years, boys 11 mg
Iron deficiency
Zinc deficiency
Zinc toxicity
Manganese deficiency 
Iron metabolism disorder
Folate deficiency
Copper deficiency
Cerebral folate deficiency