Since phytanic acid is not endogenously produced in the human body, individuals with<unk>  are commonly placed on a phytanic acid-restricted diet and avoid the consumption of fats from ruminant animals and certain fish, such as tuna, cod, and haddock. Grass feeding animals and their milk are also avoided. Recent research has shown that CYP4 isoform enzymes could help reduce the over-accumulation of phytanic acid in vivo. Plasmapheresis is another medical intervention used to treat patients. This involves the filtering of blood to ensure there is no accumulation of phytanic acid.
Refsum disease
Shell nail syndrome
Arthritis mutilans
Fuchs' dystrophy
Dentinogenesis imperfecta
Scleroderma
Chyloderma
Xeroderma