<unk>  <unk> ECD) is a rare form of corneal dystrophy described first in 2006, based on a 4-generation family of 60 members with 9 affected males and 35 trait carriers, which led to mapping the<unk> ECD locus to<unk> q25. It manifests as severe corneal opacification or clouding, sometimes congenital, in the form of a ground glass, milky corneal tissue, and moon crater-like changes of corneal endothelium. Trait carriers manifest only<unk>  alterations resembling moon craters. As of December 2014, the molecular basis for this disease remained unknown, although 181 genes were known to be within the<unk> ECD locus, of which 68 were known to be protein-coding.
X-linked endothelial corneal dystrophy
Subepithelial mucinous corneal dystrophy
Fleck corneal dystrophy
Congenital stromal corneal dystrophy
Meesmann corneal dystrophy
Lisch epithelial corneal dystrophy
Progressive macular hypomelanosis
Schnyder crystalline corneal dystrophy