Although<unk>  was eliminated from much of the developed world in the 20th century (Australia being a notable exception), this disease persists in many parts of the developing world, particularly in communities without adequate access to water and sanitation. Environmental measures Environmental improvement: Modifications in water use, fly control, latrine use, health education, and proximity to domesticated animals have all been proposed to reduce transmission of C.<unk> tis. These changes pose numerous challenges for implementation. These environmental changes are likely to ultimately affect the transmission of ocular infection by means of lack of facial cleanliness. Particular attention is required for environmental factors that limit clean faces. A systematic review examining the effectiveness of environmental sanitary measures on the prevalence of active<unk>  in endemic areas showed that use of insecticide spray resulted in significant reductions of<unk>  and fly density in some studies. Health education also resulted in reductions of active<unk>  when implemented. Improved water supply did not result in a reduction of<unk>  incidence. Antibiotics WHO Guidelines recommend that a region should receive community-based, mass antibiotic treatment when the prevalence of active<unk>  among one- to nine-year-old children is greater than 10%. Subsequent annual treatment should be administered for three years, at which time the prevalence should be reassessed. Annual treatment should continue until the prevalence drops below 5%. At lower prevalences, antibiotic treatment should be family-based.
Trachoma
Nasal polyp
Orbital emphysema
Isthmicoma
Nasal vestibulitis
Acalvaria
Blepharitis
Tympanosclerosis