<unk>  is used for the adjunctive treatment of all forms of Parkinson's disease (postencephalitic, idiopathic, and arteriosclerotic Parkinson's) and for reduced sweating in methadone users. It seems to exert better effects in the postencephalitic and idiopathic than in the arteriosclerotic type.<unk>  is also commonly used to improve acute extrapyramidal side effects related to antipsychotic drug therapy, such as akathisia. It relieves muscle rigidity, reduces abnormal sweating related with clozapine and methadone use and salivation, improves abnormal gait, and to lesser extent, tremor. In its role as a synthetic acetylcholine antagonist,<unk>  has been analyzed as an alternative anticonvulsant for usage in the treatment of intoxication by organophosphorus nerve agents, such as sarin. It was also suggested by IV route for neuroleptic malignant syndrome. Pregnancy and lactation * Pregnancy : In animal studies<unk>  had no embryo- or fetotoxic effects. There is no sufficient clinical data on pregnant women. The drug should therefore be used cautiously during pregnancy. * Lactation :<unk>  is found in the milk of lactating women. No sufficient clinical data exists regarding effects for the newborns. Additionally,<unk>  may decrease maternal milk production. It is therefore recommended that<unk>  is not used during lactation. Children Children and adolescents aged 1 year and older may be treated. The clinical experience is mainly on the short-term treatment of acute drug induced dystonic reactions. Doses should be reduced according to the weight of the patients.
Biperiden
Seltorexant
Bocasan
Lemborexant
Mitapivat
Desomorphine
Daridorexant
Toremifene