The allergen responsible in dust mite allergy Der p 1 is known to cleave<unk>  from a cell’s surface. As<unk>  is soluble, it can move freely and interact with cells in plasma. Recent studies have shown that increased levels of soluble<unk>  cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of<unk>  and Fc epsilon RI (high-affinity IgE receptor). Patterns of<unk>  (and CD21) expression by the follicular dendritic cells in follicular lymphoma. In flow cytometry,<unk>  is helpful in the differentiation of chronic lymphocytic leukemia <unk> -positive) from mantle cell lymphoma <unk> -negative).<unk>  can also be demonstrated in germinal centre follicular dendritic cells using immunohistochemistry but is minimally expressed by benign germinal center B cells. In contrast to neoplastic mantle cells (which are negative for<unk> , the resting cells of physiologic mantle zone express<unk> . Paradoxically, Lymphomas arising from the mantle zone are generally negative for<unk> , while most B-cell chronic lymphomocytic leukaemias are positive, allowing immunohistochemistry to distinguish these conditions, which otherwise have a similar appearance. Reed–Sternberg cells are usually positive for<unk> .
CD23
CD74
CD80
CD22
CD137
CD86
IL-2 receptor
CD44