A number of structural proteins (filaggrin, keratin), enzymes (proteases), lipids, and antimicrobial peptides (defensins) contribute to maintain the important barrier function of the skin. Keratinization is part of the physical barrier formation (cornification), in which the<unk> s produce more and more keratin and undergo terminal differentiation. The fully cornified<unk> s that form the outermost layer are constantly shed off and replaced by new cells.
Keratinocyte
Nevus cell
Elliptocyte
Koilocyte
Nurse cell
Melanocyte
Neuroblast
Echinocyte