Typically<unk> s are heterodimers or multimers with a high and a low affinity component. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The structures for the extracellular domains of the receptors for interferon types, I,<unk> , and<unk> I are all known.<unk> s are tyrosine-kinase-linked receptors. The intracellular domain of<unk> s is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK family). Binding of the receptor typically leads to activation of the canonical JAK/STAT signaling pathway.
Type II cytokine receptor
Type I cytokine receptor
Thromboxane receptor
Interleukin-7 receptor
Fc receptor-like molecule
Interleukin-3 receptor
Fc receptor
Tropomyosin receptor kinase A