Deaths from<unk>  per million persons in 2012<unk>  affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. In 2010 it resulted in about 49,000 deaths globally. Onset is uncommon under the age of 15 and from then on the incidence rises with age until the age of 80. Women are affected three to five times as often as men. The age at which the disease most commonly starts is in women between 40 and 50 years of age, and for men somewhat later.<unk>  is a chronic disease, and although<unk> rely, a spontaneous remission may occur, the natural course is almost invariably one of the persistent symptoms, waxing and waning in intensity, and a progressive deterioration of joint structures leading to deformations and disability. There is an association between periodontitis and<unk>  <unk> , hypothesised to lead to enhanced generation of<unk> -related autoantibodies. Oral bacteria that invade the blood may also contribute to chronic inflammatory responses and generation of autoantibodies.
Rheumatoid arthritis
Fibromyalgia
Reactive arthritis
Psoriatic arthritis
Rheumatism
Lupus
Inflammatory arthritis
Septic arthritis