ICF is<unk>  of unknown origin, persisting or relapsing for a minimum of six consecutive months, and failing to meet the criteria for chronic<unk>  syndrome. There are no agreed upon international criteria for<unk> , however the CDC's 1994<unk>  criteria, known as the Fukuda criteria, are commonly used. Signs and symptoms * Clinically evaluated<unk>  * New or definite onset (not lifelong) * Not resulting from exertion *<unk>  persists or is relapsing for six consecutive months or longer * Fails to meet the criteria for chronic<unk>  syndrome * The cause is unknown Exclusions *<unk>  which begins within 2 years of a substance use disorder (addiction) or at any time after * major depression with psychotic or melancholic features * bipolar disorder * schizophrenia or schizophrenia-related disorders * delusional disorders * the eating disorder bulimia nervosa * dementia of any form * chronic<unk>  syndrome *<unk>  caused by an active medical condition *<unk>  caused by a previous medical condition that may not be fully resolved *<unk>  caused as a known side effect of medication * severe obesity (a body mass index greater than 45) Common medical causes of<unk>  These must be ruled out before a diagnosis of ICF can be made. * Infectious diseases including viruses and TB * Vascular diseases (affecting heart and circulation) * Toxins and drug effects including poisons and substance use (addiction) * Diseases affecting the lungs, including chronic obstructive pulmonary disease (COPD) * Endocrine and metabolic problems, e.g., thyroid diseases and diabetes * Diseases involving benign or cancerous tumours, including cancer<unk>  * Psychological or psychosocial conditions, including major depression * Anaemia, Lupus and certain autoimmune or neurological diseases * Occupational stress or other life stress and burnout * Domestic violence
Idiopathic chronic fatigue
Fatigue
Cancer-related fatigue
Chronic fatigue syndrome
Occupational burnout
Functional somatic syndrome
Medication phobia
Nicotine dependence