Generic 100 mg<unk>  capsules<unk>  package In addition to the general indications for all members of the tetracycline antibiotics group,<unk>  is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections. In Canada, in 2004,<unk>  was considered a first-line treatment for chlamydia and non-gonococcal urethritis and with cefixime for uncomplicated gonorrhea. Antibacterial Moraxella catarrhalis, Brucella melitensis, Chlamydia pneumoniae, and Mycoplasma pneumoniae are generally susceptible to<unk> , while some Haemophilus spp., Mycoplasma hominis, and Pseudomonas aeruginosa have developed resistance to varying degrees. It is used in the treatment and prophylaxis of anthrax and Leptospirosis. It is also effective against Yersinia pestis (the infectious agent of bubonic plague), and is prescribed for the treatment of Lyme disease, ehrlichiosis, and Rocky Mountain spotted fever.<unk>  is indicated for treatment of: * Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsia * Respiratory tract infections caused by Mycoplasma pneumoniae * Lymphogranuloma venereum, trachoma, inclusion conjunctivitis, and uncomplicated urethral, endocervical, or rectal infections in adults caused by Chlamydia trachomatis * Psittacosis * Nongonococcal urethritis caused by Ureaplasma urealyticum * Relapsing fever due to Borrelia recurrentis * Chancroid caused by Haemophilus ducreyi * Plague due to Yersinia pestis * Tularemia * Cholera * Campylobacter fetus infections * Brucellosis caused by Brucella species (in conjunction with streptomycin) * Bartonellosis * Granuloma inguinale (Klebsiella species) *Lyme disease When bacteriologic testing indicates appropriate susceptibility to the drug,<unk>  may be used to treat these infections caused by Gram-negative bacteria: * Escherichia coli infections * Enterobacter aerogenes (formerly Aerobacter aerogenes) infections * Shigella species infections * Acinetobacter species (formerly Mima species and Herellea species) infections * Respiratory tract infections caused by Haemophilus influenzae * Respiratory tract and urinary tract infections caused by Klebsiella species Some Gram-positive bacteria have developed resistance to<unk> . Up to 44% of Streptococcus pyogenes and up to 74% of S. faecalis specimens have developed resistance to the tetracycline group of antibiotics. Up to 57% of P. acnes strains developed resistance to<unk> . When bacteriologic testing indicates appropriate susceptibility to the drug,<unk>  may be used to treat these infections caused by Gram-positive bacteria: * Upper respiratory infections caused by Streptococcus pneumoniae (formerly Diplococcus pneumoniae) * Skin and soft tissue infections caused by Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus infections * Anthrax caused by Bacillus anthracis infection When penicillin is contraindicated,<unk>  can be used to treat: * Syphilis caused by Treponema pallidum * Yaws caused by Treponema pertenue * Listeriosis due to Listeria monocytogenes * Vincent's infection caused by Fusobacterium fusiforme * Actinomycosis caused by Actinomyces israelii * Infections caused by Clostridium species<unk>  may also be used as adjunctive therapy for severe acne. The first-line treatment for brucellosis is a combination of<unk>  and streptomycin and the second-line is a combination of<unk>  and rifampicin (rifampin). Antimalarial<unk>  is active against the erythrocytic stages of Plasmodium falciparum but not against the gametocytes of P. falciparum. It is used to prevent malaria. It is not recommended alone for initial treatment of malaria, even when the parasite is<unk> -sensitive, because the antimalarial effect of<unk>  is delayed. The World Health Organization (WHO) guidelines state that the combination of<unk>  with either artesunate or quinine may be used for the treatment of uncomplicated malaria due to P. falciparum or following intravenous treatment of severe malaria. Antihelminthic<unk>  kills the symbiotic Wolbachia bacteria in the reproductive tracts of parasitic filarial nematodes, making the nematodes sterile, and thus reducing transmission of diseases such as onchocerciasis and elephantiasis. Field trials in 2005 showed an eight-week course of<unk>  almost completely eliminates the release of microfilariae. Spectrum of susceptibility<unk>  has been used successfully to treat sexually transmitted, respiratory, and ophthalmic infections. Representative pathogenic genera include Chlamydia, Streptococcus, Ureaplasma, Mycoplasma, and others. The following represents MIC susceptibility data for a few medically significant microorganisms. * Chlamydia psittaci: 0.03 μg/mL * Mycoplasma pneumoniae: 0.016 μg/mL — 2 μg/mL * Streptococcus pneumoniae: 0.06 μg/mL — 32 μg/mL Sclerotherapy<unk>  is also used for sclerotherapy in slow-flow vascular malformations, namely venous and lymphatic malformations, as well as post-operative lymphoceles. Others Subantimicrobial-dose<unk>  (SDD) is widely used as an adjunctive treatment to scaling and root planing for periodontitis. Significant differences were observed for all investigated clinical parameters of periodontitis in favor of the scaling and root planing + SDD group where SDD dosage regimens is 20 mg twice daily for 3 months in a meta-analysis published in 2011.
Doxycycline
Oxytetracycline
Amikacin
Streptomycin
Eravacycline
Minocycline
Secnidazole
Sarecycline