<unk> inase The pathophysiology of<unk>  has several aspects. The normal function has P110δ <unk>  involved in immune system regulation. P110δ effect is not limited to the immune system; P110δ has a presence in transformed epithelial cells and cell adhesion molecules (airway inflammation), and research has been done on the possibility of P110δ in the nervous system.<unk>  effect indicates affected individuals are likely to have activation-induced cell death. Normally,<unk><unk>  signaling assists B cells and T cells to mature; however, overactive<unk><unk>  has an effect on the B and T cell differentiation (the process by which cells eventually are different from one another). Consequently, there is an inability to confront an infection, as well as early cell death. Furthermore, overproduction of said signal can cause lymphadenopathy (which is an enlargement of lymph nodes) due to excess white blood cells.
Activated PI3K delta syndrome
Flammer syndrome
STAR syndrome
HAIR-AN syndrome
PHACE syndrome
CAMFAK syndrome
TAN syndrome
Teunissen–Cremers syndrome