Mental health as a risk factor for illicit drug<unk>  or abuse.<unk>  potential The<unk>  potential of a drug varies from substance to substance, and from individual to individual. Dose, frequency, pharmacokinetics of a particular substance, route of administration, and time are critical factors for developing a drug<unk> . An article in The Lancet compared the harm and<unk>  liability of 20 drugs, using a scale from zero to three for physical<unk> , psychological<unk> , and pleasure to create a mean score for<unk> . Selected results can be seen in the chart below. Drug Mean Pleasure Psychological<unk>  Physical<unk>  Heroin 3.00 3.0 3.0 3.0 Cocaine 2.39 3.0 2.8 1.3 Tobacco 2.21 2.3 2.6 1.8 Barbiturates 2.01 2.0 2.2 1.8 Alcohol 1.93 2.3 1.9 1.6 Benzodiazepines 1.83 1.7 2.1 1.8 Amphetamine 1.67 2.0 1.9 1.1 Cannabis 1.51 1.9 1.7 0.8 Ecstasy 1.13 1.5 1.2 0.7 Capture rates Capture rates enumerate the percentage of users who reported that they had become dependent to their respective drug at some point. Drug % of users Cannabis 9% Alcohol 15.4% Cocaine 16.7% Heroin 23.1% Tobacco 31.9%
Substance dependence
Polysubstance dependence
Benzodiazepine dependence
Nicotine dependence
Amphetamine dependence
Substance Abuse
Addiction
Cocaine dependence