<unk>  <unk> , popularly known as Kennedy's disease, is a debilitating neurodegenerative disorder resulting in muscle cramps and progressive weakness due to degeneration of motor neurons in the brainstem and spinal cord and muscle wasting. The condition is associated with mutation of the androgen receptor (AR) gene and is inherited in an X-linked recessive manner. As with many genetic disorders, no cure is known, although research continues. Because of its endocrine manifestations related to the impairment of the AR gene, patients with<unk>  develop partial symptoms of androgen insensitivity syndrome (AIS) in addition to neuromuscular degeneration.<unk>  is related to other neurodegenerative diseases caused by similar mutations, such as Huntington's disease. The prevalence of<unk>  has been estimated at 2.6:100,000 males.
Spinal and bulbar muscular atrophy
Infantile progressive bulbar palsy
Ataxic cerebral palsy
Madras motor neuron disease
Multiple system atrophy
Spinal muscular atrophy
Spinal muscular atrophy with lower extremity predominance 1
Babinski–Nageotte syndrome