<unk>  is a drug that is used in neuroscience research, which acts as a potent and selective agonist for the group II metabotropic glutamate receptors (mGluR2/3). It is derived from the older mGluR group II agonist eglumegad, and led on to the development of the more potent compound<unk> -404,039, but is still widely used in research itself.<unk>  has sedative, neuroprotective, anti-addictive and anticonvulsant effects in animals, and blocks the effects of PCP and DOI, which has led to research into<unk>  and similar compounds as antipsychotic drugs for the treatment of schizophrenia in animals. There are inconsistent findings about an additional activity as a dopamine D2 receptor partial agonist.
LY-379,268
EA-4056
LY-2459989
AVN-211
RU-22930
RVT-802
MK-2048
AVN-101