The following is a list of common signs and symptoms of<unk> . * Fever * poor appetite * anterior fontanelle bulging * seizures * jitteriness * dyspnea * irritability * anorexia * vomiting * diarrhea * abdominal distention (increase in abdominal size) * neck rigidity * cyanosis * jaundice * sunset eyes (downward gaze of the eyes) * abnormal body temperature (hypo-or hyperthermia) * change of activity (lethargy or irritability) These symptoms are unspecific and may point to many different conditions. Complications Neuroimaging (X-ray imaging of the brain) is recommended to detect the complications of<unk> . Complications should be suspected when the clinical course is characterized by shock, respiratory failure, focal neurological deficits, a positive cerebrospinal fluid culture after 48 to 72 hours of appropriate antibiotic therapy, or infection with certain organisms, such as Citrobacter koseri and Cronobacter sakazakii for example. Ultrasounds are useful for early imaging to determine ventricular size and hemorrhaging. CT scans later in the therapy should be used to dictate prolonged treatment. If intracranial abscesses (collection of pus in the brain) are found, treatment consisting of a combination of surgical drainage of the abscess and antimicrobial therapy for 4 to 6 weeks is recommended. More imaging should be completed after the end of antibiotic treatment because abscesses have been found after weeks from start of treatment. Relapses have also occurred after appropriate treatment when infected by Gram-negative enteric bacilli. Hearing Loss<unk>  is one of the leading causes of acquired deafness. Nearly 8% of those with<unk>  will have a permanent sensorineural hearing loss. The longer<unk>  is left untreated, the greater the risk of seizures and permanent neurological damage such as hearing loss, memory difficulty, learning disabilities, brain damage, gait problems, kidney failure, shock, and even death. Hearing loss in those with<unk>  can occur when the body is fighting off the infection and the cells reach the inner ear where the hair cells and nerve fibers become damaged. Hearing loss can also occur after<unk>  is resolved due to an increased risk for ossification of the cochlea. Ossification of the cochlea can make it difficult to place a Cochlear Implant for hearing losses that are treated unsuccessfully with hearing aids. Bacterial<unk>  is likely to lead to hearing loss. It is important to have a hearing test as soon as possible. It would be best to complete a hearing test before leaving the hospital or within four weeks of improvement of symptoms. Fluctuating hearing loss has been observed in a large number of patients, so it is best to have routine hearing tests to monitor the hearing loss. Viral<unk>  is less likely to cause hearing loss and it is recommended to perform a hearing test if the patient is experiencing any hearing difficulties. All hearing losses are different so there is no predictive loss for<unk> . Children are assessed through behavioral testing (if old enough), Otoacoustic Emissions (OAEs), and Auditory Brainstem Response (ABR). Impact in Children for Communication If hearing loss is left undetected and/or untreated, this can lead to later acquisition of language and delayed reading skills. Since untreated<unk>  can cause brain damage and learning disabilities, children with a history of<unk>  may be developmentally delayed when compared to their typically developing peers. Laboratory features Laboratory features that are characteristic of neonatal bacterial<unk>  include: * Isolation of a bacterial pathogen from the cerebrospinal fluid by culture and/or visualization by Gram stain * Increased cerebrospinal fluid white blood cell count (typically >1000 white blood cells/μL, but may be lower, especially with Gram-positive bacteria), usually with a predominance of neutrophils * Elevated cerebrospinal fluid protein concentration (>150 mg/dL in preterm (premature birth) and >100 mg/dL in term infants) * Decreased cerebrospinal fluid glucose concentration (<20 mg/dL 1.1 mmol/L in preterm (premature birth) and <30 mg/dL 1.7 mmol/L in term (on time) infants)
Neonatal meningitis
Neonatal stroke
Shaken baby syndrome
Neonatal encephalopathy
Omphalitis of newborn
Hemolytic disease of the newborn 
Hemolytic disease of the newborn
Neonatal sepsis