RISUG works by an injection into the vas deferens, the vessel through which the<unk>  moves before ejaculation. RISUG is similar to vasectomy in that a local anesthetic is administered, an incision is made in the scrotum, and the vasa deferentia are injected with a polymer gel (rather than being cut and cauterized). In a matter of minutes, the injection coats the walls of the vasa with a clear gel made of 60 mg of the copolymer styrene/maleic anhydride (SMA) with 120 µl of the solvent dimethyl sulfoxide. The copolymer is made by irradiation of the two monomers with a dose of 0.2 to 0.24 megarad for every 40 g of copolymer and a dose rate of 30 to 40 rad/s. Dr Pradeep K. Jha, a senior scientist, worked on the effects of gamma dose rate and total dose interrelation on molecular designing and biological function of polymer. The source of irradiation is cobalt-60 gamma radiation. The effect the chemical has on<unk>  is not completely understood. Originally, researchers thought it lowered the pH of the environment enough to kill the<unk> . Guha theorizes that the polymer surface has a negative and positive electric charge mosaic. Within an hour after placement the differential charge from the gel will rupture the<unk> 's cell membrane as it passes through the vas, deactivating it before it can exit from the body.
Reversible inhibition of sperm under guidance
Spermatogenesis arrest
Immature ovum
Onselling of sperm
Products of conception
Assisted zona hatching
Fallopian tube obstruction
Ovulatory shift hypothesis