Structural formula of staurosporine, the first<unk>  to be isolated<unk> s (ICZs) are a class of compounds that are under current study due to their potential as anti-cancer drugs and the prospective number of derivatives and uses found from the basic backbone alone. First isolated in 1977, a wide range of structures and derivatives have been found or developed throughout the world. Due to the extensive number of structures available, this review will focus on the more important groups here while covering their occurrence, biological activity, biosynthesis, and laboratory synthesis.
Indolocarbazole
Dimethyl methylphosphonate
Trenbolone hexahydrobenzylcarbonate
Ridinilazole
Fursultiamine
Theramine
Flonicamid
Temgicoluril