More<unk> s<unk>  includes various conditions related to the formation of cysts in one or both kidneys. The most common subset is polycystic kidney disease (PKD) which is a genetic anomaly with two subsets, autosomal recessive polycystic kidney disease (ARPKD) and autosomal dominant polycystic kidney disease (ADPKD). Consequently, causation can be genetic, developmental, or associated with systemic disease which can be acquired or malignant. Examples of acquired<unk>  include simple cysts and medullary sponge kidney (MSK). Other types of genetic<unk>  include juvenile nephronophthisis (JNPHP), medullary<unk>  (MCKD), and glomerulocystic kidney disease (GCKD). Polycystic Kidney Disease PKD causes numerous cysts to grow in the kidneys. These cysts are filled with fluid and if they grow excessively will lead to kidney damage. Mutations in genes PKD1 and PKD2 are responsible for autosomal dominant polycystic kidney disease (ADPKD). Those genes encode for polycystic proteins and mutations regarding those genes are inherited and responsible for the disorder of autosomal dominant<unk> . In the United States, more than half a million people have PKD, making it the fourth leading cause of kidney failure. PKD affects all races and genders equally and those with PKD have a possibility of developing cysts in other organs such as liver, pancreas, spleen, ovaries, and large bowel. Usually, these latter cysts do not impose a problem. Half of patients have no manifestation of symptoms, but symptoms may include: hematuria, back or abdominal pain, or the development of hypertension. The disease is usually manifested before age 30, and 45% develop kidney failure by age 60. Mutation in the HDK1 gene is currently thought to be responsible for autosomal recessive polycystic kidney disease (ARPKD), often diagnosed shortly after birth and usually before 15 years of age.
Cystic kidney disease
Polycystic kidney disease
Medullary cystic kidney disease
Glomerulocystic kidney disease
Juvenile nephronophthisis
Medullary sponge kidney
IgA nephropathy
Page kidney