<unk> -DHET, also known as<unk> -dihydro-17α-ethynyltestosterone (17α-ethynyl-DHT) as well as 17α-ethynyl-5α-androstan-17β-ol-3-one or<unk> ,17α-pregn-20-yn-17β-ol-3-one, is a synthetic androstane steroid and a derivative of testosterone. It is specifically the combined derivative of<unk> -dihydrotestosterone (DHT) and ethisterone (17α-ethynyltestosterone). The steroid is also closely related to ethynylandrostanediol (17α-ethynyl-5α-androstane-3α,17β-diol). Analogues Some closely related synthetic<unk> -reduced steroid metabolites include<unk> -dihydronandrolone,<unk> -dihydronormethandrone,<unk> -dihydronorethandrolone,<unk> -dihydronorethisterone, and<unk> -dihydrolevonorgestrel, as well as 19-norandrosterone and 19-noretiocholanolone. Derivatives The steroidal antiandrogen zanoterone (WIN-49596), which was investigated in the 1990s for the treatment of benign prostatic hyperplasia but was never marketed, was derived from<unk> -DHET. In terms of chemical structure, it is<unk> -DHET with a pyrazole ring-containing moiety fused at the C2 and C3 positions. Synthesis A partial synthesis of<unk> -DHET from androstenedione has been published.
5α-Dihydroethisterone
3α-Androstanediol
3β-Androstanediol
8,9-Dehydroestradiol
17β-Dihydroequilin
8,9-Dehydroestrone
17α-Dihydroequilin
17β-Dihydroequilenin