The sedating/narcotic effect of<unk>  is increased by other sedating substances such as other opioids, benzodiazepines, first generation antihistamines, alcohol, and antipsychotics. In addition, opioids and especially benzodiazepines increase the risk for potentially lethal respiratory depression. Strong inhibitors of the liver enzyme CYP3A4, such as ketoconazole, moderately increase<unk>  concentrations; CYP3A4 inducers can theoretically decrease concentrations of<unk> .
Buprenorphine/naloxone
Oxycodone/naloxone
Buprenorphine/naltrexone
Fentanyl/fluanisone
Buprenorphine/samidorphan
Dextromethorphan/quinidine
Naloxone
Nalorphine dinicotinate