<unk>  (ORG-50,081) is a drug which was under development by Organon for the treatment of insomnia and vasomotor symptoms (e.g., hot flashes) associated with menopause.<unk>  is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology, including inverse agonist actions at H1 and 5-HT2 receptors and antagonist actions at α2-adrenergic receptors. As of March 2010, Merck terminated internal clinical development program for<unk> , for hot flashes and insomnia, for strategic reasons.
Esmirtazapine
Sertraline
Mirtazapine
Fluparoxan
Trimipramine
Citalopram
Carpipramine
Asenapine