When the receptor is activated to open the ion channel by agonists, the following effects are observed: * CNS: nausea and vomiting center in brain stem, anxiety, as well as anticonvulsant and pro-nociceptive activity. * PNS: neuronal excitation (in autonomic, nociceptive neurons), emesis
5-HT3 receptor
Muscarinic acetylcholine receptor M4
Baroreceptor
Trace amine-associated receptor
Prolactin-releasing peptide receptor
SK channel
Hydroxycarboxylic acid receptor 2
Norepinephrine transporter