The European Society of Intensive Care<unk> ized a consensus meeting in 1994 to create the "Sepsis-Related<unk>  Failure Assessment (SOFA)" score to describe and quantitate the degree of<unk><unk>  in six<unk>  systems. Using similar physiologic variables the<unk><unk><unk>  Score was developed. Four clinical phases have been suggested: * Stage 1: the patient has increased volume requirements and mild respiratory alkalosis which is accompanied by oliguria, hyperglycemia and increased insulin requirements. * Stage 2: the patient is tachypneic, hypocapnic and hypoxemic; develops moderate liver<unk>  and possible hematologic abnormalities. * Stage 3: the patient develops shock with azotemia and acid-base disturbances; has significant coagulation abnormalities. * Stage 4: the patient is vasopressor dependent and oliguric<unk> uric; subsequently develops ischemic colitis and lactic acidosis. Definition<unk><unk>  syndrome is the presence of altered<unk>  function in acutely ill patients such that homeostasis cannot be maintained without intervention. It usually involves two or more<unk>  systems. It calls for an immediate intervention.
Multiple organ dysfunction syndrome
Cytokine release syndrome
Tumor lysis syndrome
Systemic inflammatory response syndrome
Macrophage activation syndrome
Decompression sickness
Pulmonary-renal syndrome
Culture-bound syndrome