<unk>  refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene<unk>  seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.<unk>  of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
Therapeutic gene modulation
Epigenetic therapy
Gene therapy
Cell therapy
Host-directed therapeutics
Experimental cancer treatment
Antisense therapy
Individualized cancer immunotherapy