Thymoma is a common neoplasm arising from the thymus, the primary lymphoid organ where T cells become educated to distinguish "self" from "non self". In the setting of thymoma, abnormal thymic education occurs as a result of subtle differences in antigen processing. In TAMA these differences result in autoreactive T cells escaping from the thymus. This results in a condition similar to graft-versus-host disease.
Thymoma-associated multiorgan autoimmunity
Chronic multifocal Langerhans cell histiocytosis
Nodal marginal zone B cell lymphoma
Thymic carcinoma
Thymoma with immunodeficiency
Radiation-induced thyroiditis
Primary mediastinal B-cell lymphoma
Critical illness–related corticosteroid insufficiency