The diagnosis of<unk>  is usually made by coupling a family history of the condition with an appropriate clinical presentation and confirmation on a blood smear. In general it requires that at least 25% of erythrocytes in the specimen are abnormally elliptical in shape, though the observed percentage of elliptocytes can be 100%. This is in contrast to the rest of the population, in which it is common for up to 15% of erythrocytes to be elliptical. If some doubt remains regarding the diagnosis, definitive diagnosis can involve osmotic fragility testing, an autohaemolysis test, and direct protein assaying by gel electrophoresis.
Hereditary elliptocytosis
Diamond–Blackfan anemia
Hereditary spherocytosis
Thiamine responsive megaloblastic anemia syndrome
Myomatous erythrocytosis syndrome
Refractory anemia with excess of blasts
Refractory anemia with ring sideroblasts
Macroglobulinemia