<unk>  <unk> ,<unk>  is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In<unk> , there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene and is distinguished from other forms of AML by its responsiveness to all-trans retinoic acid (ATRA; also known as tretinoin) therapy.<unk>  was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness, with a median survival time of less than a week. Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 80-90% according to one study.
Acute promyelocytic leukemia
Prolymphocytic leukemia
Acute megakaryoblastic leukemia
Myeloid leukemia
Acute monocytic leukemia
T-cell leukemia
Monocytic leukemia
Acute erythroid leukemia