<unk>  is an anticoagulant that functions as a direct thrombin inhibitor. Brand name: Refludan, Generic:<unk>  rDNA for injection.<unk>  is a recombinant hirudin derived from yeast cells.<unk>  is almost identical to hirudin extracted from Hirudo medicinalis, having the amino acid sequence LTYTDCTESGQNLCLCEGSNVCGQGNKCILGSDGEKNQCVTGEGTPKPQSHNDGDFEEIPEEYLQ with disulfide bridges at Cys6-Cys14, Cys16-Cys28 and Cys22-Cys39, and differs from by the substitution of leucine for isoleucine at the N-terminal end of the molecule and the absence of a sulfate group on the tyrosine at position 63.<unk>  may be used as an anticoagulant when heparins (unfractionated or low-molecular-weight) are contraindicated because of heparin-induced thrombocytopenia.
Lepirudin
Hirudin
Bivalirudin
Argatroban
Palladin
Desmoteplase
Ticlopidine
Defibrotide