IgM The diagnosis of<unk>  will find the following in an affected individual via clinical features and blood test: * B lymphopenia * T lymphopenia * Hypogammaglobulinemia with low IgA * Hypogammaglobulinemia with low IgM Differencial diagnosis The DDx for<unk>  are both LIG4 syndrome, as well as Nijmegen breakage syndrome
Cernunnos deficiency
Craniodiaphyseal dysplasia
Lethal congenital contracture syndrome
Congenital distal spinal muscular atrophy
Pseudo-Hurler polydystrophy
Spinal muscular atrophies
Caudal regression syndrome
Chondrodystrophy