Chemically<unk>  functions as a carboxylic acid derivative serving non-selectively to block the prostaglandin synthesis by inhibition of prostaglandin G/H synthesis one and two. Prostaglandin functions in the body as a messenger for contraction/relaxation of smooth muscle and modulation of inflammation. Resultant, inhibition of prostaglandin synthesis prevents inflammation. The primary mechanism of action responsible for<unk> 's anti-inflammatory, antipyretic, and analgesic effects is the inhibition of prostaglandin synthesis by competitive blocking of the enzyme cyclooxygenase (COX).<unk>  is a non-selective COX inhibitor. It is considered a first-generation NSAID.
Ketorolac
Etodolac
Ketoprofen
Tramadol
Meloxicam
Indoprofen
Desmetramadol
Lornoxicam