The<unk>  supports the idea that multiple connected processes contribute to the biology of aging. Kirkwood and Kowald helped to establish the first model of this kind by connecting<unk> es and predicting specific mechanisms. In departure of investigating a single mechanistic cause or single molecules that lead to senescence, the<unk>  takes a systems biology view to integrate<unk> es in conjunction with computational models and quantitative data related to the biology of aging.
Network theory of aging
Free-radical theory of aging
Ion channel hypothesis of Alzheimer's disease
Genetics of aging
Synaptotropic hypothesis
Functional matrix hypothesis
Dopamine hypothesis of schizophrenia
Evolutionary approaches to depression