The protein encoded by this gene is a member of the<unk> amily, where amino acid sequence is highly conserved between members and throughout evolution.<unk> family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with<unk><unk><unk> s, setting in motion a cascade of downstream signals which ultimately influence cell mitogenesis and differentiation. This particular family member binds both acidic and basic<unk><unk><unk>  and plays a role in bone development and maintenance. The<unk>  protein plays a role in bone<unk>  by regulating ossification. Alternative splicing occurs and additional variants have been described, including those utilizing alternate exon 8 rather than 9, but their full-length nature has not been determined.
Fibroblast growth factor receptor 3
Netrin receptor DCC
Tumor-associated glycoprotein 72
Basigin
Thromboxane receptor
Collectin
VCAM-1
Beta-secretase 1