Head Individuals with the disorder usually have distinctive malformations of the craniofacial area including an unusually large head (macrocephaly), prominent forehead, and abnormal narrowing of both sides of the forehead (bitemporal constriction); The nose can be upturned and short with a low nasal bridge; and large ears that are abnormally rotated toward the back of the head. In many cases, affected individuals also have downward slanting eyelid folds, widely spaced eyes, drooping of the upper eyelids, inward deviation of the eyes, and other eye abnormalities including absent eyebrows and eyelashes. Gastrointestinal system
Cardiofaciocutaneous syndrome
Oculofaciocardiodental syndrome
Oto-palato-digital syndrome
Oculocerebrocutaneous syndrome
Pork–cat syndrome
Tooth and nail syndrome
Zechi-Ceide syndrome
Progeroid syndromes