<unk> , sold under the brand name Tpoxx, is an antiviral with activity against orthopoxviruses such as smallpox and monkeypox. It was the first antipoxviral drug approved in the United States. The drug works by blocking cellular transmission of the virus, thus preventing the disease.<unk>  has been effective in laboratory testing; it has been shown to protect animals from monkeypox and rabbitpox and causes no serious side effects in humans. However,<unk>  has never been used to treat a human with smallpox due to the disease's eradication. Two million doses of<unk>  are stockpiled in the US Strategic National Stockpile should an orthopoxvirus-based bioterror attack occur. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.
Tecovirimat
Bevirimat
Alcaftadine
Viaspan
Rilpivirine
Rimantadine
Rhoeadine
Amantadine