<unk>  is used at a low dose in combination with ethinylestradiol (EE), an estrogen, in combined birth control pills. It has also been used in the treatment of gynecological conditions including vaginal bleeding, oligomenorrhea, polymenorrhea, hypermenorrhea, dysmenorrhea, secondary amenorrhea, and endometriosis and in France (under the brand name Lutéran) in menopausal hormone therapy in combination with an estrogen.<unk>  is used at dosages of 1 to 2 mg/day in combined birth control pills and at dosages of 2 to 10 mg/day in the treatment of gynecological disorders. Combined birth control pills containing EE and<unk>  have been found to be useful in reducing androgen-dependent symptoms such as skin and hair conditions. Dosages of<unk>  of 15 to 20 mg/day have been found to improve hot flashes. High-dose<unk> -only tablets are used as a form of progestogen-only birth control, although they are not specifically licensed as such.<unk>  has been widely used as a means of androgen deprivation therapy in the treatment of prostate cancer and benign prostatic hyperplasia (BPH) in Japan and South Korea, but has seen little use for these indications elsewhere in the world. It is used at dosages of 50 to 100 mg/day in the treatment of prostate diseases. Similarly to cyproterone<unk>  (CPA),<unk>  shows a lower risk of hot flashes than gonadotropin-releasing hormone analogues (GnRH analogues). The medication is the only other steroidal antiandrogen besides CPA that has been approved and used for the treatment of prostate cancer; megestrol<unk>  has also been researched, but has not been approved.<unk>  has also been found to be effective in the treatment of other androgen-dependent conditions such as acne, seborrhea, hirsutism, and pattern hair loss in women, similarly to CPA. It has been studied at moderate dosages of 4 to 12 mg/day in the treatment of precocious puberty in girls. It showed similar benefits as those of medroxyprogesterone<unk>  in these girls and was found to reduce, but not abolish premature development such as breast growth and menstruation. Only slight or no axillary hair growth was observed in the girls.<unk>  has also been used as a component of hormone therapy for transgender women, similarly to CPA and spironolactone, albeit mostly only in Japan.<unk>  has been used to prevent the testosterone flare at the start of gonadotropin-releasing hormone agonist therapy in men with prostate cancer. Available forms<unk>  is available in the form of oral tablets at low doses (2 mg) in combination with EE in birth control pills (e.g., as Belara in Germany), at low to moderate doses (2, 5, 10, 25 mg) alone (e.g., as Lutéran in France and Lutoral in Mexico), and at high doses (50 mg) alone (e.g., as Prostal in Japan and Prostal-L in South Korea).
Chlormadinone acetate
Methenmadinone acetate
Chlormethenmadinone acetate
Bolandiol dipropionate
Hydroxyprogesterone heptanoate
Ethinylestradiol sulfate
Ethinylestradiol sulfonate
Androstenediol dipropionate