With most drugs, elimination half-life is a useful predictor of dosing schedules and the time needed to reach steady state concentrations. In the case of<unk> , however, it has been found that the half-life of biologic activity is far longer than the elimination half-life. For<unk> , there is no range of target concentrations because researchers found no difference between the serum concentration levels of responders and those of non-responders. Instead, the duration of action is believed to be more a function of the GABA-T resynthesis rate; levels of GABA-T do not usually return to their normal state until six days after stopping the medication.
Vigabatrin
Mitapivat
Stiripentol
Bocasan
Tasimelteon
Fosaprepitant
Influenzanet
Veristrat