The syndrome is associated with microcephaly, arthrogryposis and cleft palate and various craniofacial, respiratory, neurological and limb abnormalities, including bone and joint defects of the upper limbs,<unk><unk> s, camptodactyly and talipes equinovarus or calcaneovalgus. It is characterized by craniosynostosis, and myopathy in association with congenital generalized hypertrichosis. Patients with the disease are considered intellectually disabled. Most die in childhood. Patients often suffer from respiratory difficulties such as pneumonia, and from seizures due to dysmyelination in the brain's white matter. It has been hypothesized that the Moro reflex (startle reflex in infants) may be a tool in detecting the congenital clasped<unk>  early in infancy. The<unk>  normally extends as a result of this reflex.
Adducted thumb syndrome
Duane-radial ray syndrome
Heel pad syndrome
Anterior interosseous syndrome
Dead arm syndrome
Tarsal tunnel syndrome
Blue toe syndrome
Ulnar tunnel syndrome