Surgical removal of the stomach <unk> tomy) is typically recommended for people after 20 years of age, and before 40 years of age in order to prevent development of<unk><unk>  adenocarcinoma. However, individuals discovering CDH1 mutations after the age of 40 may still be considered for<unk> tomy. The physical and psychological health of each individual should be considered in determining the optimal time to perform this operation. Younger individuals may wish to delay this procedure, and are often monitored with endoscopies and random biopsies. In addition, all individuals testing positive receive an initial endoscopy, at which any lesion is biopsied, as<unk><unk>  frequently begins without symptoms. Females with CDH1 mutations also have an elevated risk of lobular breast carcinoma. Frequent screening for breast<unk>  with both mammography and breast MRI is common and recommended for these individuals. The risk of colon<unk>  in those with CDH1 mutations is still unclear. Due to the mild risk that may be associated, individuals often receive screening colonoscopies at age 40, five years prior to the recommendation in the general population.
Hereditary diffuse gastric cancer
Hereditary nonpolyposis colorectal cancer
Juvenile polyposis syndrome
Coeliac disease
Tropical sprue
Attenuated familial adenomatous polyposis
Familial adenomatous polyposis
Serrated polyposis syndrome