<unk>  can be caused by diverse medical conditions, but is most often associated with end-stage cancer, known as cancer<unk> . About 50% of all cancer patients suffer from<unk> . Those with upper gastrointestinal and pancreatic cancers have the highest frequency of developing a<unk>  symptom. Prevalence of<unk>  rises in more advanced stages and is estimated to affect 80% of terminal cancer patients. Congestive heart failure, AIDS, chronic obstructive pulmonary disease, and chronic kidney disease are other conditions that often cause<unk> .<unk>  can also be the result of advanced stages of cystic fibrosis, multiple sclerosis, motor neuron disease, Parkinson's disease, dementia, tuberculosis, multiple system atrophy, mercury poisoning, Crohn's disease, trypanosomiasis, rheumatoid arthritis, and celiac disease as well as other systemic diseases.
Cachexia
Neurosis
Fatigue
Heat intolerance
Xerostomia
Anorexia 
Thermophobia
Sedation