<unk><unk>  in a patient consuming 2 packs of cigarette per day Smoking or the use of nicotine-containing drugs is the cause to<unk> ,. Also tar-components (benzopyrenes) are known to stimulate melanocytes to melanin production, and other unknown toxic agents in tobacco may also be the cause. These chemical agents have a polycyclic, chain-like structure. Environmental tobacco<unk> from parents is causing<unk>  in their children Swedish snuff causes a small elevation of oral melanin pigmented individuals from 3.0% to 4.7%. Nicotine tablets have shown to stimulate to melanin pigmentation of the oral mucosa.
Smoker's melanosis
Riehl melanosis
Becker's nevus
Spitz nevus
Hori's nevus
Drug-induced pigmentation
PUVA keratosis
Diabetic dermadrome