Diagnosis of<unk>  is made with a combination of physical and clinical evaluations. The presence of frontal and temporal<unk><unk>  is the main factor when diagnosing a patient with this disease. In the late stages of the disease, patients have been noted to develop impaired coordination, overresponsive reflexes, and even seizures. MRI testing is used to study and diagnose patients with this disease. A study conducted on four patients with this disease yielded similar MRI results despite their slightly differing symptoms. Genetic testing can show whether or not the individual has a mutation in the<unk> 1 gene, which accounts for 75% of all cases.
Megalencephalic leukoencephalopathy with subcortical cysts
Leukoencephalopathy with neuroaxonal spheroids
Leukoencephalopathy with vanishing white matter
Camel spongiform encephalopathy
Diffuse intrinsic pontine glioma
Powassan encephalitis
Neurodegeneration with brain iron accumulation
Wernicke encephalopathy