<unk>  hemosiderosis of the central nervous system is a disease of the brain resulting from chronic iron deposition in neuronal tissues associated with cerebrospinal fluid. This occurs via the deposition of hemosiderin in neuronal tissue, and is associated with neuronal loss, gliosis, and demyelination of neuronal cells. This disease was first discovered in 1908 by R.C. Hamill after performing an autopsy. Detection of this disease was largely post-mortem until the advent of MRI technology, which made diagnosis far easier.<unk>  is largely considered a rare disease, with less than 270 total reported cases in scientific literature as of 2006, and affects people of a wide range of ages with men being approximately three times more frequently affected than women. The number of reported cases of<unk>  has increased with advances in MRI technology, but it remains a rare disease.
Superficial siderosis
Geographic atrophy
Neurofibrillary tangle
Polymicrogyria
Posterior cortical atrophy
Amyloid plaques
Hippocampal sclerosis
Hemosiderin hyperpigmentation