Antibiotics Azithromycin (single oral dose of 20 mg/kg) or topical tetracycline (1% eye ointment twice a day for six weeks). Azithromycin is preferred because it is used as a single oral dose. Although it is expensive, it is generally used as part of the international donation program organized by Pfizer. Azithromycin can be used in children from the age of six months and in pregnancy. As a community-based antibiotic treatment, some evidence suggests that oral azithromycin was more effective than topical tetracycline, but no consistent evidence supported either oral or topical antibiotics as being more effective. Antibiotic treatment reduces the risk of active<unk>  in individuals infected with chlamydial<unk> tis. Surgery For individuals with trichiasis, a bilamellar tarsal rotation procedure is warranted to direct the lashes away from the globe. Evidence suggests that use of a lid clamp and absorbable sutures would result in reduced lid contour abnormalities and granuloma formulation after surgery. Early intervention is beneficial as the rate of recurrence is higher in more advanced disease. Lifestyle measures The WHO-recommended SAFE strategy includes: * Surgery to correct advanced stages of the disease * Antibiotics to treat active infection, using azithromycin * Facial cleanliness to reduce disease transmission * Environmental change to increase access to clean water and improved sanitation Children with visible nasal discharge, discharge from the eyes, or flies on their faces are at least twice as likely to have active<unk>  as children with clean faces. Intensive community-based health education programs to promote face-washing can reduce the rates of active<unk> , especially intense<unk> . If an individual is already infected, washing one's face is encouraged, especially a child, to prevent reinfection. Some evidence shows that washing the face combined with topical tetracycline might be more effective in reducing severe<unk>  compared to topical tetracycline alone. The same trial found no statistical benefit of eye washing alone or in combination with tetracycline eye drops in reducing follicular<unk>  amongst children.
Trachoma
Nasal polyp
Orbital emphysema
Isthmicoma
Nasal vestibulitis
Acalvaria
Blepharitis
Tympanosclerosis