<unk>  is a porous white or white with a yellowish or brownish tint mass and prepared in ampules 1500 IU or 3000 IE with mannitol excipient (up to 15 mg for 1500 IE dos or up to 20 mg (for 3000 IE dose). The active ingredient belongs to the hyaluronidases family of enzymes that catalyse the degradation of hyaluronic acid. By catalyzing the hydrolysis of hyaluronan, a constituent of the body's extracellular matrix (ECM), hyaluronidase lowers the viscosity of hyaluronan, thereby increasing tissue permeability... It is, therefore, often used in medicine in conjunction with other drugs to speed their dispersion and delivery. It also increases the absorption rate of parenteral fluids given by hypodermoclysis, and is an adjunct in subcutaneous urography for improving resorption of radiopaque agents. Hyaluronidases are also used for extravasation of hyperosmolar solutions. Approved applications include: Gynaecology: treatment and prevention of adhesive process in lesser pelvis during inflammatory diseases of internal genital organs, including tubo-peritoneal infertility, intrauterine synechiae, chronic endometritis. Urology: treatment of chronic prostatitis, interstitial cystitis. Pulmonology and phthisiology: treatment of pneumosclerosis, fibrosing alveolitis, and tuberculosis (fibro-cavity, infiltrative, tuberculoma). Orthopaedics: treatment of joint contracture, arthrosis, Marie-Striinipell disease, haematomas.
Bovhyaluronidase azoximer
Mucrocetin
Alglucosidase alfa
Vestronidase alfa
Avalglucosidase alfa
Acemannan
Gadobenic acid
Elapegademase