<unk><unk>  hormone (GnRH)<unk>  also known as Isolated<unk><unk>  hormone (GnRH) deficiency (IGD) is a rare autosomal recessive genetic and endocrine syndrome which is characterized by inactivating mutations of the<unk><unk>  hormone receptor (GnRHR) and thus an<unk>  of the receptor to<unk><unk>  hormone (GnRH), resulting in a partial or complete loss of the ability of the gonads to synthesize the sex hormones. The condition manifests itself as isolated hypogonadotropic hypogonadism (IHH), presenting with symptoms such as delayed, reduced, or absent puberty, low or complete lack of libido, and infertility, and is the predominant cause of IHH when it does not present alongside anosmia.
Gonadotropin-releasing hormone insensitivity
Follicle-stimulating hormone insensitivity
Mild androgen insensitivity syndrome
Partial androgen insensitivity syndrome
Kallmann syndrome
Complete androgen insensitivity syndrome
Adrenocorticotropic hormone deficiency
Androgen insensitivity syndrome