<unk><unk>  (IR) tissue injury is the resultant pathology from a combination of factors, including tissue hypoxia, followed by tissue damage associated with re-oxygenation. IR injury contributes to disease and mortality in a variety of pathologies, including myocardial infarction,<unk>  stroke, acute kidney injury, trauma, circulatory arrest, sickle cell disease and sleep apnea. Whether resulting from traumatic vessel disruption, tourniquet application, or shock, the extremity is exposed to an enormous flux in vascular perfusion during a critical period of tissue repair and regeneration. The contribution of this<unk>  and subsequent<unk>  on post-traumatic<unk>  tissues is unknown; however, it is likely that similar to cardiac and kidney tissue, IR significantly contributes to tissue fibrosis.
Ischemia-reperfusion injury of the appendicular musculoskeletal system
Complications of prolonged standing
Radiation-induced lumbar plexopathy
Microdamage in bone
Anterior vertebral body tethering
Shoulder injury related to vaccine administration
Repetitive strain injury
Gram-negative toe web infection