<unk>  <unk>  is the collection of symptoms and signs associated with median neuropathy at the<unk>  tunnel. Most<unk>  is related to idiopathic compression of the median nerve as it travels through the wrist at the<unk>  tunnel (IMNCT). Idiopathic means that there is no other disease process contributing to pressure on the nerve. Most<unk>  is due to IMNCT. As with most structural issues, it occurs in both hands, and the strongest risk factor is genetics. Other conditions can cause<unk>  such as wrist fracture or rheumatoid arthritis. After fracture, swelling, bleeding, and deformity compress the median nerve. With rheumatoid arthritis, the enlarged synovial lining of the tendons causes compression. The main symptoms are numbness and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. People often report pain, but pain without tingling is not characteristic of IMNCT. Rather, the numbness can be so intense that they are described as painful. Symptoms are typically most troublesome at night. Untreated, and over years to decades, IMNCT causes loss of sensibility and weakness and shrinkage (atrophy) of the muscles at the base of the thumb. The only certain risk factor for IMNCT is genetics. All other risk factors are open to debate. It is important to consider IMNCT separately from<unk>  in diseases such as rheumatoid arthritis. Diagnosis of IMNCT can be made with a high probability based on characteristic symptoms and signs. IMNCT can be measured with electrodiagnostic tests. People wake less often at night if they wear a wrist splint. Injection of corticosteroids may or may not alleviate better than simulated (placebo) injections. There is no evidence that corticosteroid injection alters the natural history of the disease, which seems to be a gradual progression of neuropathy. Surgery to cut the transverse<unk>  ligament is the only known disease modifying treatment.
Carpal tunnel syndrome
Radial tunnel syndrome
Ulnar tunnel syndrome
Calpainopathy
Tarsal tunnel syndrome
Sciatica
Median nerve palsy
Anterior interosseous syndrome