<unk>  is the preferred medical treatment for metal poisoning, including acute mercury, iron (including in cases of sickle-cell disease and thalassemia), arsenic, lead, uranium, plutonium and other forms of toxic metal poisoning. The<unk> g agent may be administered intravenously, intramuscularly, or orally, depending on the agent and the type of poisoning.<unk> g agents There are a variety of common<unk> g agents with differing affinities for different metals, physical characteristics, and biological mechanism of action. For the most common forms of heavy metal intoxication – lead, arsenic, or mercury – a number of<unk> g agents are available. Dimercaptosuccinic acid (DMSA) has been recommended for the treatment of lead poisoning in children by poison control centers around the world. Other<unk> g agents, such as 2,3-dimercaptopropanesulfonic acid (DMPS) and alpha lipoic acid (ALA), are used in conventional and alternative medicine. Some common<unk> g agents are ethylenediaminetetraacetic acid (EDTA), 2,3-dimercaptopropanesulfonic acid (DMPS), and thiamine tetrahydrofurfuryl disulfide (TTFD). Calcium-disodium EDTA and DMSA are only approved for the removal of lead by the Food and Drug Administration while DMPS and TTFD are not approved by the FDA. These drugs bind to heavy metals in the body and prevent them from binding to other agents. They are then excreted from the body. The<unk> g process also removes vital nutrients such as vitamins C and E, therefore these must be supplemented. The German Environmental Agency (Umweltbundesamt) listed DMSA and DMPS as the two most useful and safe<unk> g agents available. Chelator Used in Dimercaprol (British anti-Lewisite; BAL) * acute arsenic poisoning * acute mercury poisoning * lead poisoning (in addition to EDTA) * Lewisite poisoning (for which it was developed as an antidote) Dimercaptosuccinic acid (DMSA) *lead poisoning * arsenic poisoning * mercury poisoning Dimercapto-propane sulfonate (DMPS) * severe acute arsenic poisoning * severe acute mercury poisoning Penicillamine Mainly in: * copper toxicity Occasionally adjunctive<unk>  in: *gold toxicity *arsenic poisoning *lead poisoning *rheumatoid arthritis Ethylenediamine tetraacetic acid (calcium disodium versenate) (CaNa2-EDTA) *lead poisoning Deferoxamine, Deferasirox and Deferiprone *acute iron poisoning *iron overload
Chelation therapy
Cobalt therapy
Alcohol detoxification
Antipsychotic switching
Reperfusion therapy
Glucagon rescue
Activated charcoal cleanse
Psychedelic therapy