<unk>  <unk>  is a medical condition that involves an accumulation of acid in the body due to a failure of the kidneys to appropriately acidify the urine. In renal physiology, when blood is filtered by the kidney, the filtrate passes through the tubules of the nephron, allowing for exchange of salts, acid equivalents, and other solutes before it drains into the bladder as urine. The metabolic acidosis that results from<unk>  may be caused either by insufficient secretion of hydrogen ions (which are acidic) into the latter portions of the nephron (the distal tubule) or by failure to reabsorb sufficient bicarbonate ions (which are alkaline) from the filtrate in the early portion of the nephron (the proximal tubule). Although a metabolic acidosis also occurs in those with chronic kidney disease, the term<unk>  is reserved for individuals with poor urinary acidification in otherwise well-functioning kidneys. Several different types of<unk>  exist, which all have different syndromes and different causes.<unk>  is usually an incidental finding based on routine blood draws that show abnormal results. Clinically, patients may present with vague symptoms such as dehydration, mental status changes, or delayed growth in adolescents. The word acidosis refers to the tendency for<unk>  to cause an excess of acid, which lowers the blood's pH. When the blood pH is below normal (7.35), this is called acidemia. The metabolic acidosis caused by<unk>  is a normal anion gap acidosis.
Renal tubular acidosis
Distal renal tubular acidosis
Proximal renal tubular acidosis
Isotonic hyponatremia
Hyperchloremic acidosis
Hypotonic hyponatremia
Cystinuria
Normal anion gap acidosis