For individuals being treated with benzodiazepines such as alprazolam (Xanax) for<unk><unk> s, even small amounts of<unk>  may have negative effects on treatment.<unk>  is able to negate the effects of benzodiazepines which can lead to heightened levels of<unk>  and even panic attacks. Studies have linked<unk>  intake to increased rates of cytotoxicity and cell death by necrosis associated with benzodiazepine use. However, this phenomenon (thought to be mediated via TSPO) is also present with benzodiazepine use alone. The clinical significance of<unk> -benzodiazepine<unk>  cytotoxicity in humans is unclear and has not been shown to be harmful. Although benzodiazepines are effective at managing acute<unk><unk><unk>  symptoms, avoiding<unk>  is generally recommended rather than increasing benzodiazepine intake. Treatments for<unk>  tend to focus on abstinence from or a reduction of<unk>  intake and behavioral therapy. Some doctors may recommend a continuance of<unk>  consumption but with the provision that the patient actively takes note of physiological changes that happen after<unk>  intake. The goal of this approach is to help patients better understand the effects of<unk>  on the body and to distinguish threatening symptoms from normal reactions.
Caffeine-induced anxiety disorder
Cannabinoid hyperemesis syndrome
Clinical endocannabinoid deficiency syndrome
Masked depression
Functional somatic syndrome
Benzodiazepine withdrawal syndrome
Benzodiazepine dependence
Nicotine withdrawal