<unk>  (pruritus) has many causes. Allergies and inflammatory skin disease all produce<unk>  as a symptom. Pathophysiologically, the sensation of the<unk>  is poorly understood. Nevertheless, there are many known inducers of<unk> . Histamine is wildly known as an inducer of the<unk>  sensation. Other substances known to induce<unk>  are substance P, cytokines, and proteases. Temperature also has an effect. It is conventional opinion that applied cold temperature inhibits<unk>  by inhibiting C-fiber activity. However, studies have also described paradoxical phenomena associated with temperature and<unk> , where applied short-term moderate cold temperature stimulus enhanced the<unk> . Such a phenomenon might be explained by "paradoxical heat", which is when one has the perception of heat when, in fact, the skin is innocuously cooled. Thus, the exact effect of temperature on<unk>  remains unclear, with different levels of heat and cold proven to both enhance and inhibit<unk> . Alcohol is known to have close interactions with histamine release. Alcohol both stimulates the release of histamine from mast cells and inhibits its degradations by inhibiting diamine oxidase. Though histamine is used by the body to mediate alcohol-induced gastric and intestinal damage as well as alcohol flushing, it is possible that elevated levels of histamine might have a correlation with<unk>  (or even<unk>  in general).
Referred itch
Pain out of proportion
Baricity
Referred pain
Coolie itch
Body odor
Ground itch
Grain itch