<unk> D is most prevalent in Caucasian women and Asian men over the age of 60. The invasive form occurs in 5-25% of all<unk> D patients and 17-30% of the cases involve an underlying adenocarcinoma. 10-20% of<unk> D is of the secondary form. Approximately 10% of patients develop invasive adenocarcinoma that may progress to metastatic<unk> . The<unk>  affects regions that are rich in apocrine secretions. 65%<unk> D occurs at the vulva, followed by 15% at perianal areas and 14% at the male genitalia. In terms of the vulva, the labia majora is the site that is most often involved, followed by labia minora, clitoris and perineum.<unk> D originating at the vulva can spread to the upper vaginal mucosa and cervix. Other areas where<unk> D can be found, although very rarely, include: the axillae, eyelids, external auditory canal, umbilical region, trunk and extremities.
Extramammary Paget's disease
Acral lentiginous melanoma
Arsenical keratosis
Acral fibrokeratoma
Hydrocarbon keratosis
Seborrheic keratosis
Lentigo maligna melanoma
Actinic keratosis