The diagnosis of LPF depends on its clinical presentation almost exclusively in newborn and young children and, most importantly, its histopathology as determined on biopsied intact tissue or fine-needle aspiration to obtain a sampling of the tumor's cells. Intact tissue samples typical show abundant mature-appearing adipose (i.e. fat) tissue mixed with a minor component of oval-shaped or spindle-shaped fibroblast-like cells some of which have a pseudolipoblast-like morphology. Needle biopsies should show these cells. However, LPF histopathology can vary widely between cases. The cited gene abnormalities in the above section are insufficient to support a diagnosis of LPF although further study of these and discoveries of other gene abnormalities may do so. The histopathology of<unk> -like neural tumors (LPF-NT) can closely resemble LPF tumors. Unlike LPF tumors, however, LPF-NT tumors have been diagnosed in adults in more than 27% of cases with the remaining cases diagnosed in children not younger than 14 months/old. Moreover, LPF tumor cells, but not LPF tumor cells, commonly express a fusion gene containing a part of the NTRK1 gene.
Lipofibromatosis
Actinic elastosis
Phakomatosis
Fibromatosis
Pyogenic granuloma
Fibrin ring granuloma
Lipoblastomatosis
Universal angiomatosis