The six membered benzene ring causes skin sensitization. The sulfonyl nitrate part of the compound causes ocular toxicity. Acute toxicity data - lethal dose type of test species route of exposure dose toxic effects rodent - rat oral 534 mg/kg details of toxic effects not reported other than lethal dose value LD50 rodent - mouse oral 468 mg/kg details of toxic effects not reported other than lethal dose value LD50 rodent - mouse intraperitoneal 250 mg/kg behavioral - ataxia; endocrine - hypoglycemia; nutritional and gross metabolic - body temperature decrease LD mammal - dog oral >1 gm/kg behavioral - tremor, muscle weakness; gastrointestinal - nausea or vomiting Tumorigenic data type of test species route or exposure dose toxic effects TDLo - Lowest published toxic dose rodent - rat oral 214 gm/kg/52W-C tumorigenic - equivocal tumorigenic agent by RTECS criteria; kidney, ureter, bladder - tumors
Glysobuzole
Glybuzole
Amivantamab
Memantine
Rilonacept
Lepra 
Pivagabine
Nusinersen