The<unk>  (also known as the cholesterol hypothesis) is a medical theory postulating a link between blood cholesterol levels and the occurrence of cardiovascular disease. A summary from 1976 described it as: "measures used to lower the plasma<unk> s in patients with hyperlipidemia will lead to reductions in new events of coronary heart disease". It states, more concisely, that "decreasing blood cholesterol ... significantly reduces coronary heart disease". An accumulation of evidence has led to the acceptance of the<unk>  by most of the medical community, however, some significant controversy has existed such as in The International Network of Cholesterol Skeptics (THINCS).
Lipid hypothesis
Activation-synthesis hypothesis
Sliding filament theory
Functional matrix hypothesis
Direct pathway
Uncoupling 
Synaptotropic hypothesis
Weathering hypothesis