Ovarian tumors by incidence and risk of ovarian cancer, with<unk> <unk><unk>  tumors at right. Classification of<unk> s by their histology Cell/tissue normal location Ovary (female) Testicle (male) Mixed Cell/tissue type<unk> <unk>  Granulosa cell tumour Sertoli cell tumour Gynandroblastoma<unk> <unk> Thecoma, Fibroma Leydig cell tumour Gynandroblastoma Mixed Sertoli–Leydig cell tumour Gynandroblastoma Tumour types in order of prevalence *Granulosa cell tumour. This tumour produces granulosa cells, which normally are found in the ovary. It is malignant in 20% of women diagnosed with it. It tends to present in women in the 50-55yo age group with post menopausal vaginal bleeding. Uncommonly, a similar but possibly distinct tumour, juvenile granulosa cell tumour, presents in pre-pubertal girls with precocious puberty. In both groups, the vaginal bleeding is due to oestrogen secreted by the tumour. In older women, treatment is total abdominal hysterectomy and removal of both ovaries. In young girls, fertility sparing treatment is the mainstay for non-metastatic disease. * Sertoli cell tumour. This tumour produces Sertoli cells, which normally are found in the testicle. This tumour occurs in both men and women. *Thecoma. This tumour produces theca of follicle, a tissue normally found in the ovarian follicle. The tumour is almost exclusively benign and unilateral. It typically secretes estrogen, and as a result women with this tumour often present with postmenopausal bleeding. *Leydig cell tumour. This tumour produces Leydig cells, which normally are found in the testicle and tend to secrete androgens. *Sertoli–Leydig cell tumour. This tumour produces both Sertoli and Leydig cells. Although both cell types normally occur in the testicle, this tumour can occur in the ovary. *Gynandroblastoma. A very rare tumour producing both ovarian (granulosa and/or theca) and testicular (Sertoli and/or Leydig) cells or tissues. Typically it consists of adult-type granulosa cells and Sertoli cells, but it has been reported with juvenile-type granulosa cells. It has been reported to occur in the ovary usually, rarely in the testis. Due to its rarity, the malignant potential of this tumour is unclear; there is one case report of late metastasis. *Sex<unk>  tumour with annular tubules, abbreviated SCTAT. These are rare tumours that may be sporadic or associated with Peutz–Jeghers syndrome.
Sex cord–gonadal stromal tumour
Sertoli cell tumour
Granulosa cell tumour
Germ cell tumor
Ovarian germ cell tumors
Dysgerminoma
Leydig cell tumour
Gonadoblastoma