A typical response among users is to have another hit of the drug; however, the levels of dopamine in the brain take a long time to replenish themselves, and each hit taken in rapid succession leads to progressively less intense highs. Nonetheless, a person might binge for 3 or more days without sleep, while inhaling hits from a pipe. Use of<unk>  in a binge, during which the drug is taken repeatedly and at increasingly high doses, leads to a state of increasing irritability, restlessness, and paranoia. This may result in full-blown paranoid psychosis, in which the individual loses touch with reality and experiences auditory hallucinations. Large amounts of<unk>  (several hundred milligrams or more) intensify the user's high, but may also lead to bizarre, erratic, and violent behavior. Large amounts can induce tremors, vertigo, muscle twitches, paranoia, or, with repeated doses, a toxic reaction closely resembling amphetamine poisoning.
Crack cocaine
Khat
Monkeypox
Herbal smokeless tobacco
Nicotine polacrilex
Dissolvable tobacco
Herbal cigarette
Areca nut