Alcohol dehydrogenase immunoreactivity in a healthy cornea (top), in Fuchs' dystrophy and keratoconic cornea. Diaminobenzidine stains<unk> s in the cross-section of cornea. From Mootha et al., 2009.<unk> s may play a role in different corneal disorders. According to comparative research, their functions drastically diverge from the norm in keratoconus, the most frequent form of corneal dystrophy. In keratoconic corneas they have been shown to commit apoptosis far away from any epithelial injury; a hypothesis exists that presents excessive<unk>  apoptosis as a major pathological event in keratoconus. According to one study, patient's<unk> s have decreased levels of one of the alcohol dehydrogenase subforms, they secrete significantly less superoxide dismutase 3, according to another.
Corneal keratocyte
Corneal endothelium
Iris pigment epithelium
Retinal ganglion cell
Melanocyte
Corneal limbus
Corneal button
Layer of rods and cones