<unk>  is a congenital disease in which the pupils of the subject are narrower than 2 mm in diameter.<unk>  is associated with juvenile-onset glaucoma. It is also associated with Pierson syndrome chararacterized by<unk>  and congenital nephrotic syndrome. The defect is in the Laminin beta 2 gene on chromosome 3p21 which encodes a protein essential to the glomerular basement membrane. It is also part of the known manifestations of a born infant to a mother suffering from uncontrolled hyperglycemia. Other symptoms include transposition of great vessels, respiratory distress secondary to surfactant defect, sacral agensis, jitteriness, irritability, and lethargy due to rebound fetal hypoglycemia. Congenital<unk>  is an autosomal dominant trait. However, it can also occur sporadically.
Microcoria
Macrostomia
Oxycephaly
Macrocephaly
Otocephaly
Acephaly
Microdontia
Brachycephaly