<unk>  cancer is the most prevalent type of cancer among women globally, with 685,000 deaths recorded worldwide in 2020. The most commonly used treatment methods for<unk>  cancer include surgery, radiotherapy and chemotherapy. Some of these treated patients experience disease relapse and metastasis. The aggressive progression and recurrence of this disease has been attributed the presence of a subset of tumor<unk> s known as<unk> s <unk> s). These<unk> s possess the abilities of self-renewal and tumor initiation, allowing them to be drivers of metastases and tumor growth. The microenvironment in which these<unk> s reside is filled with residential inflammatory<unk> s that provide the needed signaling cues for<unk> -mediated self-renewal and survival. The production of cytokines allows these<unk> s to escape from the primary tumor and travel through the circulation to distant organs, commencing the process of metastasis. Due to their significant role in driving disease progression,<unk> s represent a new target by which to treat the tumor at the source of metastasis.
Breast cancer stem cell
Cancer stem cell
Benign proliferative breast disease
Endocrine therapy resistance in breast cancer
Inflammatory breast cancer
Cancer-associated fibroblast
Mucinous carcinoma of the breast
Hormone receptor positive breast tumor