Although reliable and comprehensive incidence statistics are nonexistent, LCLC-RP is a rare tumor, with only a few hundred cases described in the scientific literature to date. LCLC's made up about 10% of lung cancers in most historical series, equating to approximately 22,000 cases per year in the U.S. Of these LCLC cases, it is estimated that about 1% will eventually develop the<unk><unk>  during tumor evolution and progression. In one large series of 902 surgically resected lung cancers, only 3 cases (0.3%) were diagnosed as LCLC-RP. In another highly selected series of large-cell lung carcinoma cases, only 4 of 45 tumors (9%) were diagnosed as the<unk><unk>  using the 10% criterion, but another 10 (22%) had at least some<unk> <unk>  formation. It appears likely, therefore, that LCLC-RP probably comprises between 0.1% and 1.0% of all lung malignancies. Similar to nearly all variants of lung carcinoma,<unk>  appears to be highly related to tobacco smoking. It also appears to be significantly more common in males than in females.
Large-cell lung carcinoma with rhabdoid phenotype
Epithelial-myoepithelial carcinoma of the lung
Salivary gland–like carcinoma of the lung
Mucinous cystadenocarcinoma of the lung
Basaloid large cell carcinoma of the lung
Large cell neuroendocrine carcinoma of the lung
Plexiform angiomyxoid myofibroblastic tumor
Atypical pulmonary carcinoid tumour