There are a number of mechanisms that attempt to explain the cause, progression and the link between<unk> ,<unk>  and Alzheimer's disease Insulin resistance Insulin resistance reduces the body's sensitivity to insulin. This is a sign an individual has prediabetes or has progressed to develop<unk> . The result is high glucose levels in the blood which leave the individual feeling tired and weak in most cases.<unk>  is a condition which can follow after initially being diagnosed with<unk> . In<unk> , the neurons lack glucose, a key element needed for the neurons to function effectively in body however more specifically the hippocampus and the cerebral cortex. This deficiency can lead to a decrease in memory, judgement and the ability to reason, of which are key symptoms of Alzheimer's disease. Hyperglycemia caused by oxidative stress The consumption of carbohydrates, fatty (unsaturated) acids, small antioxidant consumption and little exercise are diabetic factors that contribute to oxidative stress within the brain. Oxidative stress is an imbalance of free radicals such as superoxide, hydroxyl radical and nitric oxide radical which can create damage to the cells and tissue in the body. This resulting imbalance leads to a slow decrease in cognition which can be severe in patients in<unk> . Lipid peroxidation<unk>  causes change in patient's blood profile which increases the likelihood of the patient's cells to experience damage through lipid peroxidation. Lipid peroxidation involves free radicals taking electrons from lipids in the cell membrane, causing cell destruction. This process has been observed in patients with Alzheimer's disease. One of the main biomarkers of oxidative stress is lipid peroxidation as acids including polyunsaturated fatty acids are known to characteristically associate with free radicals. Therefore lipid peroxidation can cause enhancements in oxidative stress, a main process in<unk>  and Alzheimer's disease.
Type 3 diabetes
Type 3c diabetes
Type 1 diabetes
Type 2 diabetes
Prediabetes
Cystic fibrosis–related diabetes
Lifestyle causes of type 2 diabetes
Maturity onset diabetes of the young