The<unk>  was an industrial accident that occurred around 12:37 PM on July 10, 1976, in a small chemical manufacturing plant approximately north of Milan in the Lombardy region of Italy. It resulted in the highest known exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in residential populations, which gave rise to numerous scientific studies and standardized industrial safety regulations. The EU industrial safety regulations are known as the<unk>  II Directive. This accident was ranked eighth in a list of the worst man-made environmental disasters by Time magazine in 2010.
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