The<unk> V gene is located on the short arm of chromosome 16 (16p13). Many different mutations of the<unk> V gene can cause the disorder. Having one mutation is unlikely to cause the condition. Having two mutations either a copy from both parents, or two different mutations, one from each parent is the threshold for a genetic diagnosis of<unk> . However, most individuals who comply with the genetic diagnosis of<unk>  remain asymptomatic or undiagnosed. Whether this is due to modifier genes or environmental factors remains to be established.
Familial Mediterranean fever
Chilaiditi syndrome
Scleroderma
Hereditary angioedema
Kawasaki disease
Sjögren syndrome
Chilblain lupus erythematosus
Periodic fever syndrome