The most common adverse effects (occurring in at least 1% of those taking the drug) include agitation, anxiety, confusion, dizziness, irritability, abnormal sensations, like pins and needles, without a physical cause, sleep disturbances (e.g. sleeplessness) and a drop in blood pressure upon standing up. Less frequent side effects include movement disorders (like tremors), precipitation of angle closure glaucoma and the potentially fatal side effects paralytic ileus and neuroleptic malignant syndrome. Dropout incidence due to side effects is about 20%. Side effects with unknown frequency include (but are not limited to): * Digestive effects: * Constipation * Diarrhoea * Dry mouth * Nausea * Taste disturbances * Vomiting * Effects on the heart: * Arrhythmia * ECG changes * Abnormal heart rhythm * Heart block * Sudden cardiac death * High heart rate * Blood abnormalities: * Abnormal blood cell counts * Blood sugar changes * Low blood sodium levels * Breast effects: * Breast enlargement, including in males. * Spontaneous breast milk secretion that is unrelated to breastfeeding or pregnancy * Effects on the skin: * Abnormal sweating * Hair loss * Hives * Increased light sensitivity * Itching * Rash * Mental / neurologic effects: * Delusions * Hallucinations * Headache * Hypomania/mania * Seizures * Suicidal behaviour * Other effects: * Appetite changes * Blurred vision * Difficulty emptying the bladder * Difficulty talking due to difficulties in moving the required muscles * Liver problems * Ringing in the ears * Sexual dysfunction, such as impotence * Swelling * Weight changes Withdrawal If abruptly stopped after regular use it can cause withdrawal effects such as sleeplessness, irritability and excessive sweating.
Lofepramine
Diphenhydramine
Sibutramine
Dezocine
Palonosetron
Zotepine
Avacopan
Quinupramine