There are three different types of<unk> s: early<unk> s, late<unk> s, and recycling<unk> s. They are distinguished by the time it takes for endocytosed material to reach them, and by markers such as rabs. They also have different morphology. Once endocytic vesicles have uncoated, they fuse with early<unk> s. Early<unk> s then mature into late<unk> s before fusing with lysosomes. Early<unk> s mature in several ways to form late<unk> s. They become increasingly acidic mainly through the activity of the V-ATPase. Many molecules that are recycled are removed by concentration in the tubular regions of early<unk> s. Loss of these tubules to recycling pathways means that late<unk> s mostly lack tubules. They also increase in size due to the homotypic fusion of early<unk> s into larger vesicles. Molecules are also sorted into smaller vesicles that bud from the perimeter membrane into the<unk>  lumen, forming intraluminal vesicles (ILVs); this leads to the multivesicular appearance of late<unk> s and so they are also known as multivesicular<unk> s or multivesicular bodies (MVBs). Removal of recycling molecules such as transferrin receptors and mannose 6-phosphate receptors continues during this period, probably via budding of vesicles out of<unk> s. Finally, the<unk> s lose RAB5A and acquire RAB7A, making them competent for fusion with lysosomes. Fusion of late<unk> s with lysosomes has been shown to result in the formation of a 'hybrid' compartment, with characteristics intermediate of the two source compartments. For example, lysosomes are more dense than late<unk> s, and the hybrids have an intermediate density. Lysosomes reform by recondensation to their normal, higher density. However, before this happens, more late<unk> s may fuse with the hybrid. Some material recycles to the plasma membrane directly from early<unk> s, but most traffics via recycling<unk> s. *Early<unk> s consist of a dynamic tubular-vesicular network (vesicles up to 1 µm in diameter with connected tubules of approx. 50 nm diameter). Markers include RAB5A and RAB4, Transferrin and its receptor and EEA1. *Late<unk> s, also known as MVBs, are mainly spherical, lack tubules, and contain many close-packed intraluminal vesicles. Markers include RAB7, RAB9, and mannose 6-phosphate receptors. In addition to this, the late<unk> l membrane (and consequently the lysosome) contains a peculiar and unique Lipid, named BMP or LBPA, which is not found in any other eukaryotic cell membrane. *Recycling<unk> s are concentrated at the microtubule organizing center and consist of a mainly tubular network. Marker; RAB11. More subtypes exist in specialized cells such as polarized cells and macrophages. Phagosomes, macropinosomes and autophagosomes mature in a manner similar to<unk> s, and may require fusion with normal<unk> s for their maturation. Some intracellular pathogens subvert this process, for example, by preventing RAB7 acquisition. Late<unk> s/MVBs are sometimes called endocytic carrier vesicles, but this term was used to describe vesicles that bud from early<unk> s and fuse with late<unk> s. However, several observations (described above) have now demonstrated that it is more likely that transport between these two compartments occurs by a maturation process, rather than vesicle transport. Another unique identifying feature that differs between the various classes of<unk> s is the lipid composition in their membranes. Phosphatidyl inositol phosphates (PIPs), one of the most important lipid signaling molecules, is found to differ as the<unk> s mature from early to late. PI(4,5)P2 is present on plasma membranes, PI(3)P on early<unk> s, PI(3,5)P2 on late<unk> s and PI(4)P on the trans Golgi network. These lipids on the surface of the<unk> s help in the specific recruitment of proteins from the cytosol, thus providing them an identity. The inter-conversion of these lipids is a result of the concerted action of phosphoinositide kinases and phosphatases that are strategically localized
Endosome
Nucleus 
Dendrosome
Myelomere
Liposome
Droplet nucleus
Cubosome
Bioptome