Absorption Variable, yet relatively rapid rate of absorption with a time to peak concentration of 2.8-3.9 hours. Bioavailability is close to 100% and food has no effect on the bioavailability of<unk>  but may affect the rate of absorption. Metabolism<unk>  is metabolized mostly by the CYP3A4 isoenzyme, but also CYP3A7 and CYP3A5, to 2-(sulphamoylacetyl)-phenol via reductive cleavage of the 1,2-benzisoxazole ring.
Zonisamide
Galantamine
Mesuximide
Ethosuximide
Phenytoin
Propazepine
Levetiracetam
Carbamazepine