The first symptom is typically diabetes mellitus, which is usually diagnosed around the age of 6. The next symptom to appear is often optic atrophy, the wasting of optic nerves, around the age of 11. The first signs of this are loss of colour vision and peripheral vision. The condition worsens over time, and people with optic atrophy are usually blind within 8 years of the first symptoms. Life expectancy of people suffering from this<unk>  is about 30 years.
Wolfram syndrome
Joubert syndrome
Kaufman oculocerebrofacial syndrome
Rett syndrome
De Barsy syndrome
TORCH syndrome
Foster Kennedy syndrome
Williams syndrome