<unk>  is a discipline that emphasizes<unk>  in health care through the prevention, reduction, reporting and analysis of error and other types of unnecessary harm that often lead to adverse<unk>  events. The frequency and magnitude of avoidable adverse events, often known as<unk>  incidents, experienced by<unk> s was not well known until the 1990s, when multiple countries reported significant numbers of<unk> s harmed and killed by medical errors. Recognizing that healthcare errors impact 1 in every 10<unk> s around the world, the World Health Organization (WHO) calls<unk>  an endemic concern. Indeed,<unk>  has emerged as a distinct healthcare discipline supported by an immature yet developing scientific framework. There is a significant transdisciplinary body of theoretical and research literature that informs the science of<unk> .
Patient safety
Good clinical practice
Patient participation
Patient group directions
Clinical research ethics
Public security
Good clinical data management practice
Automotive safety