<unk>  is characterized by a clinical triad present in 97% of people with<unk>  by the time they turn 10 years old: # Thickened toenails # Plantar keratoderma # Plantar pain that may require some patients to use wheelchairs, canes, crutches, and pain medications due to its severity Other signs and symptoms found in<unk>  include: * Thickened fingernails * Palmar keratoderma * Oral leukokeratosis * Cysts, including steatocystoma multiplex * Follicular hyperkeratosis * Natal or prenatal teeth * Blisters * Excessive sweating of the palms and soles * Excess earwax production * Ear pain * Hoarseness * Angular chelitis * Fingernail and toenail infections
Pachyonychia congenita
Platonychia
Lipoatrophia annularis
Linitis plastica
Hapalonychia
Steatopygia
Koilonychia
Trachonychia