<unk>  is active against a wide range of bacterial infections, mostly<unk> ram-negative bacteria including Pseudomonas, Proteus, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Serratia, and the<unk> ram-positive Staphylococcus.<unk>  is used in the treatment of respiratory tract infections, urinary tract infections, blood, bone and soft tissue infections of these susceptible bacteria. There is insufficient evidence to support<unk>  as the first line treatment of Neisseria<unk> onorrhoeae infection.<unk>  is not used for Neisseria meningitidis or Legionella pneumophila bacterial infections (because of the risk of the person<unk> oing into shock from lipid A endotoxin found in certain<unk> ram-negative organisms).<unk>  is also useful against Yersinia pestis (responsible for plague), its relatives, and Francisella tularensis (the organism responsible for tularemia often seen in hunters and trappers). Some Enterobacteriaceae, Pseudomonas spp., Enterococcus spp., Staphylococcus aureus and other Staphylococcus spp. have varying degrees of resistance to<unk> . Special populations Pregnancy and breastfeeding<unk>  is not recommended in pregnancy unless the benefits outweigh the risks for the mother.<unk>  can cross the placenta and several reports of irreversible bilateral congenital deafness in children have been seen. Intramuscular injection of<unk>  in mothers can cause muscle weakness in the newborn. The safety and efficacy for<unk>  in nursing mothers has not been established. Detectable<unk>  levels are found in human breast milk and in nursing babies. Elderly In the elderly, renal function should be assessed before beginning therapy as well as during treatment due to a decline in<unk> lomerular filtration rate.<unk>  levels in the body can remain higher for a longer period of time in this population.<unk>  should be used cautiously in persons with renal, auditory, vestibular, or neuromuscular dysfunction. Children<unk>  may not be appropriate to use in children, including babies. Studies have shown higher serum levels and a longer half-life in this population. Kidney function should be checked periodically during therapy. Long-term effects of treatment can include hearing loss and balance problems. Hypocalcemia, hypokalemia, and muscle weakness have been reported when used by injection.
Gentamicin
Piperacillin
Cefotaxime
Cefazolin
Levofloxacin
Carbenicillin
Acetic acid 
Acetic acid