The<unk> , also called the<unk> , is a neurobiological hypothesis of neuronal growth and synapse formation. The hypothesis was first formulated by J.E. Vaughn in 1988, and remains a focus of current research efforts. The<unk>  proposes that input from a presynaptic to a postsynaptic cell (and maturation of excitatory synaptic inputs) eventually can change the course of synapse formation at dendritic and axonal arbors. This synapse formation is required for the development of neuronal structure in the functioning brain.
Synaptotropic hypothesis
Activation-synthesis hypothesis
Center-surround antagonism
Synaptic pharmacology
Lipid hypothesis
Thrifty gene hypothesis
Functional matrix hypothesis
Co-stimulation