<unk>  formation can have one of four outcomes: propagation, embolization, dissolution, and organization and recanalization. # Propagation of a<unk>  occurs towards the direction of the heart and involves the accumulation of additional platelets and fibrin. This means that it is anterograde in veins or retrograde in arteries. # Embolization occurs when the<unk>  breaks free from the vascular wall and becomes mobile, thereby traveling to other sites in the vasculature. A venous embolus (mostly from deep vein<unk> is in the lower limbs) will travel through the systemic circulation, reach the right side of the heart, and travel through the pulmonary artery, resulting in a pulmonary embolism. Arterial<unk> is resulting from hypertension or atherosclerosis can become mobile and the resulting emboli can occlude any artery or arteriole downstream of the<unk>  formation. This means that cerebral stroke, myocardial infarction, or any other organ can be affected. # Dissolution occurs when the fibrinolytic mechanisms break up the<unk>  and blood flow is restored to the vessel. This may be aided by fibrinolytic drugs such as Tissue Plasminogen Activator (tPA) in instances of coronary artery occlusion. The best response to fibrinolytic drugs is within a couple of hours, before the fibrin meshwork of the<unk>  has been fully developed. # Organization and recanalization involves the ingrowth of smooth muscle cells, fibroblasts and endothelium into the fibrin-rich<unk> . If recanalization proceeds it provides capillary-sized channels through the<unk>  for continuity of blood flow through the entire<unk>  but may not restore sufficient blood flow for the metabolic needs of the downstream tissue.
Thrombus
Thrombosis
Abscess
Enema
Thrombocythemia
Platelet plug
Embolus
Hernia