The<unk>  (PMI) is a U.S. Government initiative to control and eliminate<unk> , one of the leading global causes of premature death and disability. The initiative was originally launched by U.S.<unk>  George W. Bush in 2005, and has been continued by each successive U.S.<unk> . PMI was originally created with a mission to "reduce<unk> -related mortality by 50 percent across 15 high-burden countries in sub-Saharan Africa". PMI has since expanded to 24<unk> -endemic countries in sub-Saharan Africa and 3 additional countries in the Greater Mekong Subregion of Southeast Asia, where it seeks to further reduce<unk>  burden and assist countries in achieving<unk>  elimination. PMI works closely with national<unk>  programs and global partners including the World Health Organization, Roll Back<unk> , and Global Fund. Global<unk>  efforts, including those of PMI, have cut<unk>  mortality by over 60%, saved nearly 7 million lives, and prevented more than 1 billion<unk>  cases between 2000 and 2015. PMI currently supports<unk>  prevention and control for over 500 million at-risk people in Africa.
President's Malaria Initiative
Medicines for Malaria Venture
Global Research Collaboration for Infectious Disease Preparedness
Singaporean measures against Middle East respiratory syndrome
Commission on HIV/AIDS and Governance in Africa
London Declaration on Neglected Tropical Diseases
Harvard AIDS Initiative
Birth control in Africa