<unk>  hypersegmentation can be defined as the presence of<unk> s whose nuclei have six or more lobes or the presence of more than 3% of<unk> s with at least five nuclear lobes. This is a clinical laboratory finding. It is visualized by drawing blood from a patient and viewing the blood smeared on a slide under a microscope. Normal<unk> s are uniform in size, with an apparent diameter of about 13 μm in a film. When stained,<unk> s have a segmented nucleus and pink/orange cytoplasm under light microscope. The majority of<unk> s have three nuclear segments (lobes) connected by tapering chromatin strands. A small percentage have four lobes, and occasionally five lobes may be seen. Up to 8% of circulating<unk> s are unsegmented (‘band’ forms). The presence of<unk> s is an important diagnostic feature of megaloblastic anaemias. Hypersegmentation can also be seen in many other condition but with relatively less diagnostic significance. Hypersegmentation can sometimes be difficult to assert since interobserver variation is high and segmentation may vary with race. A 1996 study performed in the United States found that blacks have a greater<unk>  segmentation than whites.
Hypersegmented neutrophil
Intraepithelial lymphocyte
Tingible body macrophage
Binucleated cells
Lipid-laden alveolar macrophage
Small cleaved cells
Neutropenia
Touton giant cell