Heřmanský–Pudlák<unk>  (often written<unk>  or abbreviated HPS) is an extremely rare autosomal recessive disorder which results in oculocutaneous albinism (decreased pigmentation), bleeding problems due to a platelet abnormality (platelet storage pool defect), and storage of an abnormal fat-protein compound (lysosomal accumulation of ceroid lipofuscin). It is considered to affect around 1 in 500,000 people worldwide, with a significantly higher occurrence in Puerto Ricans, with a prevalence of 1 in 1800. Many of the clinical research studies on the disease have been conducted in Puerto Rico. There are eight classic forms of the disorder, based on the genetic mutation from which the disorder stems.
Hermansky–Pudlak syndrome
Keppen–Lubinsky syndrome
Sakati–Nyhan–Tisdale syndrome
Fox–Fordyce disease
Conradi–Hünermann syndrome
Kandinsky–Clérambault syndrome
Hallermann–Streiff syndrome
Shprintzen–Goldberg syndrome