Skin lesion on the upper lip due to H. capsulatum infection If symptoms of<unk>  infection occur, they start within 3 to 17 days after exposure; the typical time is 12–14 days. Most affected individuals have clinically silent manifestations and show no apparent ill effects. The acute phase of<unk>  is characterized by nonspecific respiratory symptoms, often cough or flu-like. Chest X-ray findings are normal in 40–70% of cases. Chronic<unk>  cases can resemble tuberculosis; disseminated<unk>  affects multiple organ systems and is fatal unless treated. While<unk>  is the most common cause of mediastinitis, this remains a relatively rare disease. Severe infections can cause hepatosplenomegaly, lymphadenopathy, and adrenal enlargement. Lesions often left calcification nodules as they are healed. Presumed ocular<unk>  syndrome causes chorioretinitis, where the choroid and retina of the eyes are scarred, resulting in a loss of vision not unlike macular degeneration. Despite its name, the relationship to Histoplasma is controversial. Distinct from POHS, acute ocular<unk>  may rarely occur in immunodeficiency. Complications In absence of proper treatment and especially in immunocompromised individuals, complications can arise. These include recurrent pneumonia, respiratory failure, fibrosing mediastinitis, superior vena cava syndrome, pulmonary vessel obstruction, and progressive fibrosis of lymph nodes. Fibrosing mediastinitis is a serious complication and can be fatal. Smokers with structural lung disease have higher probability of developing chronic cavitary<unk> . After healing of lesions, hard, calcified lymph nodes can erode the walls of the airway, causing hemoptysis.
Histoplasmosis
Tuberculosis
Toxoplasmosis
Talaromycosis
African histoplasmosis
Emmonsiosis
Lobomycosis
Zygomycosis