<unk><unk>  of the fetus and<unk>  (HDN) is a condition where the passage of maternal antibodies results in the hemolysis of fetal/neonatal red cells. The antibodies can be naturally occurring such as anti-A, and anti-B, or immune antibodies developed following a sensitizing event. Isoimmunization occurs when the maternal immune system is sensitized to red blood cell surface antigens. The most common causes of isoimmunization are blood transfusion, and fetal-maternal hemorrhage. The<unk>  process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. With the use of RhD Immunoprophylaxis, (commonly called Rhogam), the incidence of anti-D has decreased dramatically and other alloantibodies are now a major cause of HDN. Antibody specific Anti-Kell can cause severe anemia regardless of titer. Anti-Kell suppresses the bone marrow, by inhibiting the erythroid progenitor cells. ;anti-Kell2, anti-Kell3 and anti-Kell4 antibodies<unk> can also be caused by anti-Kell2, anti-Kell3 and anti-Kell4 IgG antibodies. These are rarer and generally the<unk>  is milder.
Hemolytic disease of the newborn 
Neonatal meningitis
Neonatal hepatitis
Michelin tire baby syndrome
Neonatal diabetes
Shaken baby syndrome
Twin-to-twin transfusion syndrome
Neonatal toxic shock-like exanthematous disease