<unk> 's principal indications are the treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occurring as part of bipolar disorders. Other uses are pre- and postoperative states with anxiety and insomnia, severe nausea / emesis (in hospitalized patients), the amelioration of anxiety and agitation due to use of selective serotonin reuptake inhibitors for depression and, off-label, the amelioration of alcohol and opioid withdrawal. It may also be used cautiously to treat nonpsychotic irritability, aggression, and insomnia in pediatric patients. An intrinsic antidepressant effect of<unk>  has been discussed, but not proven. Likewise, it is unclear if<unk>  has genuine (intrinsic) analgesic effects. However,<unk>  can be used as co-medication in severe chronic pain. Also, like most antipsychotics,<unk>  has antiemetic effects.
Chlorprothixene
Mephentermine
Triflupromazine
Alosetron
Etilamfetamine
Acetryptine
Levomepromazine
Beclamide