Mitochondrial<unk>  effect is a phenomenon where the number of mutated mtDNA has surpassed a certain<unk>  which causes the electron transport chain and ATP synthesis of a mitochondrion to fail. There isn't a set number that needs to be surpassed, however, it is associated with an increase of the number of mutated mtDNA. When there is 60-80% of mutated mtDNA present, that is said to be the<unk>  level. While 60-80% is the general<unk>  level, this is also dependent on the individual, the specific organ in question and what the specific mutation is. There are three specific types of mitochondrial<unk>  effects: phenotypic<unk>  effect, biochemical<unk>  effect and translational<unk>  effect.<unk>  is a phenomenon in which phenotypic<unk>  of a mitochondrial disease within an organ system occurs when the severity of the mutation, relative number of mutant mtDNA, and reliance of the organ system on oxidative phosphorylation combine in such a way that ATP production of the tissue falls below the level required by the tissue. The phenotype may be expressed even if the percentage of mutant mtDNA is below 50% if the mutation is severe enough.
Threshold expression
Affective spectrum
Latent inhibition
Orgastic potency
Form constant
Trends in Amplification
Concept creep
Rebound effect