A number of conditions may cause the appearance of<unk> : *Cutis marmorata telangiectatica congenita, a rare congenital condition *Sneddon syndrome – association of<unk> id vasculitis and systemic vascular disorders, such as strokes, due to underlying genetic cause *Idiopathic<unk>  – the most common form of<unk> , completely benign condition of unknown cause affecting mostly young women during the winter: It is a lacy purple appearance of skin in extremities due to sluggish venous blood flow. It may be mild, but ulceration may occur later in the summer. *Secondary<unk> : *Vasculitis autoimmune conditions:<unk> id vasculitis – with painful ulceration occurring in the lower legs *Polyarteritis nodosa *Systemic lupus erythematosus *Dermatomyositis *Rheumatoid arthritis *Lymphoma *Pancreatitis *Chronic pancreatitis *Tuberculosis *Drug-related: *Adderall (side effect) *Amantadine (side effect) *Bromocriptine (side effect) *Beta interferon treatment, e.g. in multiple sclerosis<unk>  associated with rasagiline *Methylphenidate and dextroamphetamine-induced peripheral vasculopathy *Gefitinib *Obstruction of capillaries: *Cryoglobulinaemia – proteins in the blood that clump together in cold conditions *Antiphospholipid syndrome due to small blood clots *Hypercalcaemia (raised blood calcium levels which may be deposited in the capillaries) *Haematological disorders of polycythaemia rubra vera or thrombocytosis (excessive red cells or platelets) *Infections (infective endocarditis, syphilis, tuberculosis, Lyme disease) *Associated with acute kidney injury due to cholesterol emboli status after cardiac catheterization *Arteriosclerosis (cholesterol emboli) and homocystinuria (due to Chromosome 21 autosomal recessive Cystathionine beta synthase deficiency) *Intra-arterial injection (especially in drug addicts) *Ehlers-Danlos syndrome – connective tissue disorder, often with many secondary conditions, may be present in all types *Pheochromocytoma<unk> id vasculopathy and its association with factor V Leiden mutation *FILS syndrome (polymerase ε1 mutation in a human syndrome with facial dysmorphism, immunodeficiency,<unk> , and short stature) *Primary hyperoxaluria, oxalosis (oxalate vasculopathy) *Cytomegalovirus infection (very rare clinical form, presenting with persistent fever and<unk>  on the extremities and cutaneous necrotizing vasculitis of the toes) *Generalized<unk>  induced by silicone implants for soft tissue augmentation *As a rare skin finding in children with Down syndrome *Idiopathic<unk>  with polyclonal IgM hypergammopathy *CO2 angiography (rare, reported case) *A less common skin lesion of Churg–Strauss syndrome *Erythema nodosum-like cutaneous lesions of sarcoidosis showing<unk> id changes in a patient with sarcoidosis and Sjögren's syndrome<unk>  vasculopathy associated with IgM antiphosphatidylserine-prothrombin complex antibody<unk>  vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity and prothrombin G20210A heterozygosity *As a first sign of metastatic breast carcinoma (very rare)<unk>  associated with renal cell carcinoma (rare) *Buerger's disease (as an initial symptom) *As a rare manifestation of Graves hyperthyroidism *Associated with pernicious anaemia *Moyamoya disease (a rare, chronic cerebrovascular occlusive disease of unknown cause, characterized by progressive stenosis of the arteries of the circle of Willis leading to an abnormal capillary network and resultant ischemic strokes or cerebral hemorrhages) *Associated with the use of a midline catheter *Familial primary cryofibrinogenemia.
Livedo reticularis
Vernix caseosa
Livedo racemosa
Cortical desmoid
Ligamenta flava
Chondrocranium
Glia limitans
Stratum spinosum