<unk>  is primarily used to treat major depressive disorder, obsessive-compulsive disorder, post-traumatic stress disorder, social anxiety disorder, and panic disorder. It is also occasionally used for agoraphobia, generalized anxiety disorder, premenstrual dysphoric disorder and menopausal hot flashes. Depression A variety of meta analyses have been conducted to evaluate the efficacy of<unk>  in depression. They have variously concluded that<unk>  is superior or equivalent to placebo and that it is equivalent or inferior to other antidepressants. Despite this, there was no clear evidence that<unk>  was better or worse compared with other antidepressants at increasing response to treatment at any point in time. Anxiety disorders<unk>  was the first antidepressant approved in the United States for the treatment of panic disorder. Several studies have concluded that<unk>  is superior to placebo in the treatment of panic disorder.<unk>  has demonstrated efficacy for the treatment of social anxiety disorder in adults and children. It is also beneficial for people with co-occurring social anxiety disorder and alcohol use disorder. It appears to be similar to a number of other SSRIs.<unk>  is used in the treatment of obsessive-compulsive disorder. Comparative efficacy of<unk>  is equivalent to that of clomipramine and venlafaxine.<unk>  is also effective for children with obsessive-compulsive disorder.<unk>  is approved for treatment of PTSD in the United States, Japan and Europe. In the United States it is approved for short-term use.<unk>  is also FDA-approved for generalized anxiety disorder. Menopausal hot flashes In 2013, low-dose<unk>  was approved in the US for the treatment of moderate-to-severe vasomotor symptoms such as hot flashes and night sweats associated with menopause. At the low dose used for menopausal hot flashes, side effects are similar to placebo and dose tapering is not required for discontinuation. Fibromyalgia Studies have also shown<unk>  "appears to be well-tolerated and improve the overall symptomatology in patients with fibromyalgia" but is less robust in helping with the pain involved.
Paroxetine
Atomoxetine
Dapoxetine
Citalopram
Reboxetine
Escitalopram
Duloxetine
Fluoxetine