Although symptomatic descriptions of<unk>  are similar to those of Old World diseases (e.g. measles, yellow fever, typhus), many researchers believe that it should be recognized as a separate disease. According to Francisco Hernández de Toledo, a physician who witnessed the outbreak in 1576, symptoms included high fever, severe headache, vertigo, black tongue, dark urine, dysentery, severe abdominal and chest pain, head and neck nodules, neurologic disorders, jaundice, and profuse bleeding from the nose, eyes, and mouth; death frequently occurred within 3 to 4 days. Some also describe the afflicted during this period as having spotted skin and gastrointestinal hemorrhaging, leading to bloody diarrhea, as well as bleeding from the eyes, mouth, and vagina. The onset was often rapid, and without any precursors that would suggest one was sick. The disease was characterized by an extremely high level of virulence, with death often occurring within a week of one becoming symptomatic. Due to the virulence and effectiveness of the disease, recognizing its existence in the archaeological record has been difficult.<unk> , and other diseases that work rapidly, usually do not leave impacts (lesions) on the decedent’s bones, despite causing significant damage to the gastrointestinal, respiratory, and other bodily systems.
Cocoliztli epidemics
Tanganyika laughter epidemic
Native American disease and epidemics
Virgin soil epidemic
Death rattle
symptoms of Yellow fever
Asclepiades of Bithynia
Flavescence dorée