<unk> -1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene, and is part of the<unk>  <unk>  Family ( TC# 2.A.100).<unk>  is a transmembrane protein that transports iron from the inside of a cell to the outside of the cell.<unk>  is the only known iron exporter. After dietary iron is absorbed into the cells of the small intestine,<unk>  allows that iron to be transported out of those cells and into the bloodstream.<unk>  also mediates the efflux of iron recycled from macrophages resident in the spleen and liver.<unk>  is regulated by hepcidin, a hormone produced by the liver; hepcidin binds to<unk>  and limits its iron-efflux activity, thereby reducing iron delivery to the blood plasma. Therefore, the interaction between<unk>  and hepcidin controls systemic iron homeostasis.
Ferroportin
Retinol-binding protein
Hepcidin
Hippulin
Ceruloplasmin
Haptocorrin
Beta-2 transferrin
Captodiame