The differential diagnosis of<unk>  includes other disorders that produce osteosclerosis. They constitute a wide array of disorders with clinically and radiologically diverse manifestations. Among the differential diagnosis are hereditary ostoesclerosing dysplasias such as; neuropathic infantile<unk> , infantile<unk>  with renal tubular acidosis, infantile<unk>  with immunodeficiency, infantile<unk>  with leukocyte adhesion deficiency syndrome (LAD-III), pyknodysostosis<unk>  acro-osteolytica), osteopoikilosis (Buschke–Ollendorff syndrome), osteopathia striata with cranial sclerosis, mixed sclerosing skeletal dysplasias, progressive diaphyseal dysplasia (Camurati–Engelmann disease), SOST-related sclerosing skeletal dysplasias. Besides, the differential diagnosis includes acquired conditions that induce osteosclerosis such as osteosclerotic metastasis notably carcinomas of the prostate gland and breast, Paget's disease of bone, myelofibrosis (primary disorder or secondary to intoxication or malignancy), Erdheim-Chester disease, osteosclerosing types of osteomyelitis, sickle cell disease, hypervitaminosis D, and hypoparathyroidism.
Osteopetrosis
Avascular necrosis
Leri pleonosteosis
Osteochondrosis
Osteitis fibrosa cystica
Osteofibrous dysplasia
Osteoma
Osteopoikilosis