intravenous injection of<unk> s Signs and symptoms include: * Drug seeking behavior * Increased<unk>  over time * Legal or social ramifications secondary to drug<unk>  * Multiple prescriptions from different providers * Multiple medical complications from drug<unk>  (HIV/AIDS, hospitalizations, abscesses) *<unk>  cravings * Withdrawal symptoms Addiction and dependence are components of a substance<unk>  disorder and addiction represents the more severe form.<unk>  dependence can occur as physical dependence, psychological dependence, or both. Withdrawal<unk>  withdrawal can occur with a sudden decrease in, or the cessation of,<unk> s after prolonged<unk> . Onset of withdrawal depends on which<unk>  was<unk> d last. With heroin this typically occurs five hours after<unk> , while with methadone it might not occur until two days later. The length of time that major symptoms occur also depends on the<unk> <unk> d. For heroin withdrawal, symptoms are typically greatest at two to four days, and can last for up to two weeks. Less significant symptoms may remain for an even longer period, in which case the withdrawal is known as post-acute-withdrawal syndrome. *Agitation *Anxiety *Muscle pains *Increased tearing *Trouble sleeping *Runny nose *Sweating *Yawning *Goose bumps *Dilated pupils *Diarrhea *Fast heart rate *High blood pressure *Abdominal cramps *Shakiness *Cravings *Sneezing<unk>  of withdrawal may include methadone and buprenorphine. Medications for nausea or diarrhea may also be<unk> d.<unk>  intoxication Signs and symptoms of<unk>  intoxication include: * Decreased perception of pain * Euphoria * Confusion * Desire to sleep * Nausea * Constipation * Miosis *Bradycardia *Hypotension *Hypokinesis (slowed movement) *Head nodding *Slurred speech *Hypothermia<unk>  overdose File:Fentanyl. 2 mg. A lethal dose in most people.Fentanyl 2 mg. A lethal dose in most people. Diameter of a US penny is 19.05 mm, or 0.75 inches. Signs and symptoms of<unk>  overdose include, but are not limited to: * Pin-point pupils may occur. Patient presenting with dilated pupils may still be suffering an<unk>  overdose. * Decreased heart rate * Decreased body temperature * Decreased breathing * Altered level of consciousness. People may be unresponsive or unconscious. * Pulmonary edema (fluid accumulation in the lungs) * Shock * Death
treatment of Opioid use disorder
treatment of Depression 
treatment of Bipolar disorder
treatment of Panic disorder
treatment of Eating disorder
treatment of Obsessive–compulsive personality disorder
treatment of Body image disturbance
treatment of Avoidant personality disorder