Laboratory and radiological findings * Increased liver enzyme levels (55% cases) * Increased thyroid-stimulating hormone (55% cases) * Increased erythrocyte sedimentation rate (25% cases) Cerebrospinal fluid findings: * Raised protein (25% cases) * Negative for 14–3–3 protein * May contain antithyroid antibodies * Magnetic resonance imaging abnormalities consistent with<unk>  (26% f cases) * Single photon emission computed tomography shows focal and global hypoperfusion (75% of cases) * Cerebral angiography is normal Thyroid hormone abnormalities are common (>80% of cases): * Subclinical hypothyroidism (35% of cases) * Overt hypothyroidism (20% of cases) * Hyperthyroidism (5% of cases) * Euthyroid on levothyroxine (10% of cases) * Euthyroid not on levothyroxine (20% of cases) Thyroid antibodies – both antithyroid peroxidase antibodies (anti-TPO, antithyroid microsomal antibodies, anti-M) and antithyroglobulin antibodies (anti-Tg) – in the disease are elevated, but their levels do not correlate with the severity. Electroencephalogram studies, while almost always abnormal (98% of cases), are usually not diagnostic. The most common findings are diffuse or generalized slowing or frontal intermittent rhythmic delta activity. Prominent triphasic waves, focal slowing, epileptiform abnormalities, and photoparoxysmal and photomyogenic responses may be seen. Definition A relapsing<unk>  occurs in association with<unk> 's thyroiditis, with high titers of antithyroid antibodies. Clinically, the condition may present one or more symptoms. Onset is often gradual and may go unnoticed by the patient and close associates to the patients. Symptoms sometimes resolve themselves within days to weeks, leaving a patient undiagnosed. For many other patients, the condition may result in ongoing problems with a variety of manifestations, often confusing clinicians due to the diffuse nature of symptoms. Differential diagnosis * Alzheimer's disease * Cerebrovascular accidents (stroke) * Creutzfeldt–Jakob disease * Epilepsy * Migraine (including basilar, hemiplegic, and retinal types) * Other forms of autoimmune encephalitis, including forms of limbic encephalitis such as anti-NMDA receptor encephalitis * Schizophrenia * Spontaneous cerebrospinal fluid leak * Viral encephalitis * Transient ischemic attack
Hashimoto's encephalopathy
Rasmussen's encephalitis
Japanese encephalitis
La Crosse encephalitis
Saint Louis encephalitis
Powassan encephalitis
Marburg acute multiple sclerosis
Limbic encephalitis