400 mg pills of<unk> <unk>  is used for the treatment of herpes simplex virus (HSV) and varicella zoster virus infections, including: * Genital herpes simplex (treatment and prevention) * Neonatal herpes simplex * Herpes simplex labialis (cold sores) * Shingles * Acute chickenpox in immunocompromised patients * Herpes simplex encephalitis * Acute mucocutaneous HSV infections in immunocompromised patients * Herpes of the eye and herpes simplex blepharitis (a chronic (long-term) form of herpes eye infection) * Prevention of herpes viruses in immunocompromised people (such as people undergoing cancer chemotherapy) Its effectiveness in treating Epstein-Barr virus (EBV) infections is less clear. It has not been found to be useful for infectious mononucleosis due to EBV. Valaciclovir and<unk>  act by inhibiting viral DNA replication, but as of 2016 there was little evidence that they are effective against Epstein–Barr virus, they are expensive, they risk causing resistance to antiviral agents, and (in 1% to 10% of cases) can cause unpleasant side effects.<unk>  taken by mouth does not appear to decrease the risk of pain after shingles. In those with herpes of the eye,<unk>  may be more effective and safer than idoxuridine. It is not clear if<unk>  eye drops are more effective than brivudine eye drops. Intravenous<unk>  is effective to treat severe medical conditions caused by different species of the herpes virus family, including severe localized infections of herpes virus, severe genital herpes, chickenpox and herpesviral encephalitis. It is also effective in systemic or traumatic herpes infections, eczema herpeticum and herpesviral meningitis. Reviews of research dating from the 1980s show there is some effect in reducing the number and duration of lesions if<unk>  is applied at an early stage of an outbreak. Research shows effectiveness of topical<unk>  in both the early and late stages of the outbreak as well as improving methodologically and in terms of statistical certainty from previous studies.<unk>  trials show that this agent has no role in preventing HIV transmission, but it can help slow HIV disease progression in people not taking anti-retroviral therapy (ART). This finding emphasizes the importance of testing simple, inexpensive non-ART strategies, such as<unk>  and cotrimoxazole, in people with HIV. Pregnancy Classified as a Category B drug, the CDC and others have declared that during severe recurrent or first episodes of genital herpes,<unk>  may be used. For severe HSV infections (especially disseminated HSV), IV<unk>  may also be used. Studies in mice, rabbits and rats (with doses more than 10 times the equivalent of that used in humans) given during organogenesis have failed to demonstrate birth defects. Studies in rats in which they were given the equivalent to 63 times the standard steady-state humans concentrations of the drug on day 10 of gestation showed head and tail anomalies.<unk>  is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters.<unk>  is excreted in the breast milk, therefore it is recommended that caution should be used in breast-feeding women. It has been shown in limited test studies that the nursing infant is exposed to approximately 0.3 mg/kg/day following oral administration of<unk>  to the mother. If nursing mothers have herpetic lesions near or on the breast, breast-feeding should be avoided.
Aciclovir
Penciclovir
Valganciclovir
Famciclovir
Ganciclovir
Alcaftadine
Benzylpenicillin
Amantadine