A significant side effect of insulin therapy is hypoglycemia. A meta-analysis of clinical trials published in July 2012 found 39 to 47.9 events of hypoglycemia (defined as blood glucose <56 mg/dL) per patient year, with higher rates in the more concentrated<unk>  formulation. Rates of nocturnal hypoglycemia ranged from 3.7 to 5.1 events per patient year. A more recent Cochrane systematic review found there was no significant differences in rates of diurnal, nocturnal hypoglycemia or any other studies outcomes when using<unk>  as compared to insulin glargine, insulin detemir and NPH insulin for the management of type I Diabetes in neither adults nor children.
Insulin degludec
Insulin aspart
Insulin glulisine
Insulin detemir
Lente insulin
Insulin lispro
Insulin glargine
Ultralente insulin