Data regarding overall prevalence of SPS is lacking, but it is estimated to occur in roughly 1 in 100,000. SPS is equally common among men and women. Most individuals with SPS are diagnosed between 40 and 60 years of age, with an average age of 55 years. Nearly half of individuals with SPS have a family member with colorectal cancer. Most individuals (37–70%) with SPS fulfill criterion 3 of the 2010 criteria (now criteria 2 from the 2019 classification). Of the remaining individuals with SPS, roughly half meet only criterion 1 and half meet both criteria 1 and 3 (2010 classification). Among individuals undergoing colonoscopy for the evaluation of an abnormal fecal occult blood test, the prevalence of SPS ranges from 0.34 to 0.66%. The overall prevalence of SPS is 0.03–0.5%. The prevalence of SPS is between 1 in 127 and 1 in 242 among individuals undergoing colonoscopy. SPS is associated with tobacco use. Aside from colorectal cancer, the risk of others cancers is not increased in people with SPS. Aspirin and nonsteroidal anti-inflammatory drug (NSAIDs) may be associated with a lower risk of SPS. SPS is the most common polyposis syndrome affecting the colon. There is no clear association of SPS with any cancers other than colorectal cancer. However, there is mixed evidence regarding a possible association with SPS and pancreatic cancer. Individuals with a history of lymphoma have a higher risk of developing sessile<unk> .
Serrated polyposis syndrome
Familial adenomatous polyposis
Juvenile polyposis syndrome
MUTYH-associated polyposis
Hereditary nonpolyposis colorectal cancer
Attenuated familial adenomatous polyposis
Peutz–Jeghers syndrome
Ogden syndrome