In an in vitro study in fat thalamic slices<unk>  worked by activating GABAA receptors, which decreased input resistance, depressed burst and tonic firing, especially in ventrobasal and intralaminar neurons, while at the same time increasing burst duration and mean conductance at individual chloride channels; this increased both the amplitude and decay time of inhibitory postsynaptic currents.<unk>  has been used in a study to inhibit mitochondrial electron transport in the rat heart in an attempt to preserve mitochondrial function following reperfusion. A 1988 study found that<unk>  increases benzodiazepine receptor binding in vivo with less potency than secobarbital and pentobarbital (in descending order), but greater than phenobarbital and barbital (in descending order). (Secobarbital > pentobarbital ><unk>  > phenobarbital > barbital) It has an in mice of 212mg/kg s.c.
Amobarbital
Heptobarbital
Pentobarbital
Ethallobarbital
Secobarbital
Hexobarbital
Butobarbital
Phenobarbital