There are varied etiologies related with Ohtahara syndrome. Most of the cases are associated with structural brain abnormality, though there are also cases related to genetic abnormalities (mutations).<unk>  has variable pathogenesis and structural metabolism. Another common reason rather than structural brain abnormality is inborn metabolic defects. Genetics A growing number of genetic aetiologies have been linked to the phenotype of<unk>  and Otahara syndrome and diagnosis by genetic testing can nowadays be achieved in around 50 percent of cases. Some examples of well described genetic aetiologies include: KCNQ2- DEE, SCN2A-DEE, STXBP1-DEE, CDKL5-DEE, KCNT1-DEE and UBA5-DEE. Acquired No acquired etiology is known for<unk>  although etiology remains unknown for a small percentage of patients after genetic, metabolic, and imaging workups.
Early myoclonic encephalopathy
Wernicke encephalopathy
Post-encephalitic parkinsonism
Powassan encephalitis
Ethylmalonic encephalopathy
Camel spongiform encephalopathy
Glycine encephalopathy
Autoimmune encephalitis