Autoimmune<unk><unk>  (APS) are a group of rare autoimmune disorders. APS type 2 is the most commonly seen autoimmune<unk><unk> . The incidence of APS type 2 is estimated to be 1-2 per 100,000 individuals worldwide. The prevalence of APS type 2 is estimated to be 1-4 per 100,000 individuals worldwide. Most cases of APS type 1 and type 2 are symptomatic by early thirties, while APS type 3 is generally seen in the fourth to sixth decade of life. APS usually affects individuals of the Caucasian race. In APS type 1, type 2 and type 3 females are more commonly affected than men.
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