Since low HDL is associated with an increased risk of cardiovascular disease events, elevation of HDL concentration among subjects with low HDL is advised.  The treatment of a patient with low HDL cholesterol should be individualized.  Before the initiation of any medical treatment to elevate the HDL concentration, the initial treatment should aim to reduce the LDL and non-HDL lipoprotein concentrations if they are elevated.  The management of low HDL should also begin with life style modification targeting diet, exercise, and smoking cessation.  If HDL concentration remains high despite optimal LDL and non-HDL concentrations and life style modifications, then medical therapy with fibrates or niacin might be considered among patients with risk factors of coronary artery disease or its equivalent.
High density lipoprotein medical therapy
Low density lipoprotein medical therapy
High density lipoprotein future or investigational therapies
Non-alcoholic fatty liver disease medical therapy
Metabolic syndrome dietary therapy
Low density lipoprotein future or investigational therapies
Hemochromatosis medical therapy
Metabolic syndrome medical therapy