text: The diagnosis of<unk><unk>  is made when all four of the WHO<unk>  are met. The diagnostic<unk>  may include: sustained elevation of platelet counts > 450,000,000 × 10³/L, bone marrow biopsy specimen showing proliferation, mainly of the megakaryocytic lineage with increased numbers of enlarged, mature megakaryocytes and no significant increase or left-shift of neutrophil granulopoiesis or erythropoiesis, not meeting WHO<unk>  for polycythemia vera, PMF, CML, MDS, or other myeloid neoplasm, and demonstration of JAK2 617VF or other clonal marker, or in the absence of a clonal marker, no evidence for reactive<unk> .
option_0: Essential thrombocytosis diagnostic criteria
option_1: Glanzmann's thrombasthenia patient information
option_2: Glanzmann's thrombasthenia physical examination
option_3: Glanzmann's thrombasthenia laboratory findings
option_4: Polycythemia vera diagnostic criteria
option_5: Essential thrombocytosis physical examination
option_6: Immune Thrombocytopenia epidemiology and demographics
option_7: Thrombotic thrombocytopenic purpura physical examination