text: <unk> (sublingual) is an analgesic opioid that is FDA approved for the treatment of breakthrough cancer pain, in opioid-tolerant patients, pain, chronic (severe), in opioid-tolerant patients requiring a long-term daily around-the-clock opioid analgesic.. There is a Black Box Warning for this drug as shown here.  Common adverse reactions include dermatologic: application site reaction (adults, 1% or greater ; pediatrics, 3% to 10% ), diaphoresis (adults: transdermal 10% or greater , sublingual 1% or greater ; pediatrics: transdermal 1% or greater ), pruritus (transdermal, 3% to 10% ; sublingual, 1% or greater gastrointestinal: abdominal pain (transdermal, 3% to 10% ; sublingual, 1% or greater ), constipation (adults, 10% or greater ; pediatrics, 3% to 10% ), diarrhea (adults: transdermal 3% to 10% , sublingual 1% or greater ; pediatrics: transdermal 1% or greater ), indigestion (transdermal, 3% to 10% ; sublingual, 1% or greater ), loss of appetite (transdermal, 3% to 10% ; sublingual, 1% or greater ), nausea (10% or greater ), vomiting (10% or greater ), xerostomia (adults: transdermal 10% or greater , sublingual 1% or greater ; pediatrics: transdermal 1% or greater ), neurologic: asthenia (adults, 9.7% or greater ; pediatrics, 3% to 10% ), confusion  (adults: transdermal 10% or greater , sublingual 1% or greater ; pediatrics: transdermal 1% or greater ), dizziness (adults, 3% to 10% ; pediatrics, 1% or greater ), feeling nervous (3% to 10% ), headache (transdermal, 3% to 10% ; sublingual, 1% or greater ), insomnia (adults, 1% or greater ; pediatrics, 3% to 10% ), somnolence (adult, 1% to 19% ; pediatrics, 16% ), psychiatric: Anxiety (adults, 3% to 10% ; pediatrics, 1% or greater ), depression (adults: transdermal 3% to 10% , sublingual 1% or greater ; pediatrics: transdermal 1% or greater ), euphoria (3% to 10% ), hallucinations (adults: transdermal 3% to 10%, sublingual 1% or greater ; pediatrics: transdermal 1% or greater ), renal: urinary retention (adults: transdermal 3% to 10% , sublingual less than 1% ; pediatrics: transdermal 1% or greater ), respiratory: dyspnea (adults: transdermal 3% to 10%, sublingual 10.4% ; pediatrics: transdermal 1% or greater ), upper respiratory infection (3% to 10% ), other: Fatigue (transdermal, 3% to 10% ; sublingual, 1% or greater ), influenza-like symptoms (3% to 10% ).
option_0: Fentanyl 
option_1: Remifentanil
option_2: Ketamine
option_3: Alfentanil
option_4: Propofol
option_5: Etomidate
option_6: Sevoflurane
option_7: Mirfentanil