text: <unk>  (abbreviated as<unk>  or<unk>  is a common infectious disease caused by Mycobacterium<unk> .<unk>  most commonly involves the lungs as the organism thrives in high oxygen environments, but it can also cause disease in the central nervous system, the lymphatic system, the circulatory system, the genitourinary system, bones, joints and even the skin. Over<unk> -third of the world's population has been exposed to M.<unk> , and new infections occur at a rate of<unk>  per second.  Not all individuals exposed to the bacterium develop clinically overt<unk>  infection; in fact, asymptomatic, latent<unk>  infection discovered by screening is more common. Approximately,<unk>  in ten latent infections progresses to active (symptomatic)<unk>  disease, which, if left untreated, carries mortality rates of up to 50%.  Symptoms include shortness of breath, hemoptysis, fever, chills, night sweats, and weight loss.  Several treatment regimens are available for the latent and active forms of<unk> . Classically, a prolonged course of 6-9 months of a single agent (rifampin or isoniazid) is administered to patients with latent<unk> , while a more aggressive course that consists of 4 major anti-tuberculous agents (rifampin, isoniazid, ethambutol, pyrazinamide) is reserved for patients with active disease.
option_0: Tuberculosis
option_1: Miliary tuberculosis
option_2: Aspergilloma
option_3: Aspergillosis
option_4: Sarcoidosis
option_5: Histoplasmosis
option_6: Invasive aspergillosis
option_7: Asbestosis