text: <unk>  is the metabolism of<unk> s, their biochemical modification or degradation, usually through specialized enzymatic systems.<unk>  often converts lipophilic chemical compounds into more readily excreted polar products. Its rate is an important determinant of the duration and intensity of the pharmacological action of<unk> s.<unk>  can result in toxication or detoxication - the activation or deactivation of the chemical.
  While both occur, the major metabolites of most<unk> s are detoxication products.<unk> s are almost all xenobiotics.
  Other commonly used organic chemicals are also<unk> s, and are metabolized by the same enzymes as<unk> s.
  This provides the opportunity for<unk> -drug and<unk> -chemical interactions or reactions.
option_0: Drug metabolism
option_1: Cell signaling
option_2: Photosynthesis
option_3: Carbohydrate metabolism
option_4: Heat transfer
option_5: Coagulation
option_6: Signal transduction
option_7: Wound healing