text: Pernicious anemia (also called Addison's anemia) is a type of red blood cell disorder caused by impaired vitamin B12 metabolism. Vitamin B12 is primarily absorbed by the small intestine, after being bound to intrinsic factor secreted by parietal cells of gastric mucosa. When this process is disrupted by conditions like atrophic gastritis, celiac disease, small bowel resection etc, B12 deficiency ensues.<unk>  <unk>  is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.<unk>  is a clonal bone marrow stem cell disorder in which proliferation of precursor and mature granulocytes (neutrophils, eosinophils, and basophils) occurs.  It is a type of myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome. <unk>  is caused by a mutation in BCR-ABL gene. The most potent risk factor in the development of<unk>  is ionizing radiation.Chronic<unk>  leukemia may be classified into five phases: chronic phase, accelerated phase, blast crisis, relapsed or recurrent<unk>  and refractory disease. Historically, it has been treated with chemotherapy, interferon, bone marrow transplantation, and targeted therapies.
option_0: Chronic myelogenous leukemia
option_1: Acute myeloid leukemia
option_2: Chronic neutrophilic leukemia
option_3: Myeloid leukemia
option_4: Chronic lymphocytic leukemia
option_5: Acute monocytic leukemia
option_6: Prolymphocytic leukemia
option_7: Lymphoid leukemia