text: <unk> <unk>  is an autosomal dominant spinocerebellar degeneration caused by an expansion of a CAG repeat encoding a polyglutamine tract in the atrophin-1 protein. It is also known as Haw River Syndrome and Naito-Oyanagi disease. Although this condition was perhaps first described by Smith et al. in 1958, and several sporadic cases have been reported from Western countries, this disorder seems to be very rare except in Japan.
  There are at least eight neurodegenerative diseases that are caused by expanded CAG repeats encoding polyglutamine (polyQ) stretches. The expanded CAG repeats create an adverse gain-of-function mutation in the gene products. Of these diseases,<unk>  is most similar to Huntington's disease.
option_0: Dentatorubral-pallidoluysian atrophy
option_1: Corticobasal degeneration
option_2: Spinal autonomic dysreflexia
option_3: Multiple system atrophy
option_4: Klumpke paralysis
option_5: Amyotrophic lateral sclerosis pathophysiology
option_6: Cerebral atrophy
option_7: Motor neuron disease