text: The<unk>  of<unk><unk>  depends on the subtype. Lemierre's syndrome is initiated by an infection of the head and neck region.  During the primary infection, Fusobacterium necrophorum colonizes the infection site and the infection spreads to the parapharyngeal space. The bacteria then invade the peritonsillar blood vessels where they can spread to the internal jugular vein. In this vein, the bacteria cause the formation of a thrombus containing these bacteria. The pathogenesis of pelvic vein<unk><unk>  is thought to include injury to the intima of the pelvic vein caused by a spreading uterine infection, bacteremia, and endotoxins, which can also occur secondary to the trauma of delivery or surgery. Pylephlebitis is due to an abdominal infection that drains into the portal venous system.  The most commonly isolated organism is Bacteroides fragilis, which facilitates coagulation via the capsular and surface components. Capsular polysaccharides activate macrophages therefore initiating the clotting cascade while the surface component accelerates fibrin cross-linking.
option_0: Suppurative thrombophlebitis pathophysiology
option_1: Lymphangitis pathophysiology
option_2: Portal vein thrombosis pathophysiology
option_3: Suppurative thrombophlebitis risk factors
option_4: Deep vein thrombosis pathophysiology
option_5: Suppurative thrombophlebitis causes
option_6: Lymphangitis risk factors
option_7: Cholesterol emboli syndrome pathophysiology