text: <unk>  (also known as "Thymic dysplasia with normal immunoglobulins":85) is an autosomal recessive congenital immunodeficiency condition due to underdevelopment of the thymus. An association with CD44 has been proposed.
  The defect is a type of purine nucleoside phosphorylase deficiency with inactive phosphorylase. This results in an accumulation of deoxy-GTP which inhibits ribonucleotide reductase.  Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides.  Thus, DNA replication is inhibited and cells cannot replicate.
option_0: Nezelof syndrome
option_1: Van der Woude syndrome
option_2: Wildervanck syndrome
option_3: Pretzel Syndrome
option_4: Yunis-Varon syndrome
option_5: Mungan syndrome
option_6: Kearns-Sayer syndrome
option_7: Vogt-Koyanagi-Harada syndrome