text: A<unk>  is a hormone antagonist acting upon<unk> s.
  It has been demonstrated that<unk> s are implicated in the inflammatory cascade leading to asthma.<unk>  modifiers are an important therapeutic advance in managing asthma.
option_0: Leukotriene antagonist
option_1: Mast cell stabilizer
option_2: H₂-receptor antagonist
option_3: COX-2 inhibitor
option_4: TNF inhibitor
option_5: Proteasome inhibitor
option_6: Protein kinase inhibitor
option_7: Adrenergic agonist