text: The incidence of<unk> <unk>  ulcer is approximately 1500 per 100,000<unk>  individuals world wide. Among the US veterans the incidence of active<unk> <unk>  ulcers is approximately 500 per 100,000 individuals. On the other hand the incidence of active<unk> <unk>  ulcers in United Kingdom has been estimated 220 per 100,000 individuals. Furthermore it's prevalence has been reported 170 per 100,000 individuals among the United Kingdom population. The 5 year risk of mortality in<unk>  patients with a<unk>  ulcer is 2.5 times higher than<unk>  individuals without a<unk>  ulcer. Based on 2 studies with different follow up duration, mortality rate of<unk> <unk>  has been estimated as 10% and 24% in 16 months and 5 years follow up, respectively. Based on a systematic review and metanalysis done on diabetes patients,<unk> <unk>  was more common among older patients. White people develop<unk>  peripheral neuropathy (which is a serious risk factor for<unk> <unk>  more frequently. In 1987, Borch-Johnsen et al. described a male preponderance for the development of severe microvascular complications and<unk> <unk>  disease is not an exception to this rule. Highest prevelance of<unk> <unk>  has been reported in North America. In contrast, Oceania has the lowest reported prevelance of<unk> <unk> .
option_0: Diabetic foot epidemiology and demographics
option_1: Peripheral arterial disease epidemiology and demographics
option_2: Diabetic neuropathy epidemiology and demographics
option_3: Diabetic nephropathy epidemiology and demographics
option_4: Varicose veins epidemiology and demographics
option_5: Gout epidemiology and demographics
option_6: Gangrene epidemiology and demographics
option_7: Peripheral arterial disease classification