text: <unk>  syndrome could be the result or complication of various causes affecting the normal function of Proximal convoluted tubule (PCT); in a simple and useful classification method, the causes could be classified as:
  Genetic causes
  Accumulation of a toxic substance  (e.g. Cystinosis, Tyrosinemia, Lysinuric Protein Intolerance, Glycogen Storage Diseases, Galactosemia, Wilson, Fructose Intolerance)
  Energy provision failure (e.g. Mitochondriopathies)
  Disruption of endocytosis and intracellular transport mechanisms (e.g. ARC syndrome, Lowe syndrome and Dent disease).
  Exogenous causes (e.g. Heavy metals exposure, Drugs, Chemotherapy)
  Acquired causes (e.g. Multiple myeloma, Amyloidosis, Paroxysmal nocturnal hemoglobinuria)
  Accumulation of a toxic substance  (e.g. Cystinosis, Tyrosinemia, Lysinuric Protein Intolerance, Glycogen Storage Diseases, Galactosemia, Wilson, Fructose Intolerance)
  Energy provision failure (e.g. Mitochondriopathies)
  Disruption of endocytosis and intracellular transport mechanisms (e.g. ARC syndrome, Lowe syndrome and Dent disease).
option_0: Fanconi syndrome causes
option_1: Noonan syndrome causes
option_2: Hurler syndrome causes
option_3: Cowden syndrome causes
option_4: Cretinism causes
option_5: Tuberous sclerosis causes
option_6: Phenylketonuria causes
option_7: Bannayan-Riley-Ruvalcaba syndrome causes