text: The<unk>  (also known as<unk> 's<unk>  or the<unk><unk>  mechanism) states that the more the ventricle is filled with blood during diastole (end-diastolic volume), the greater the volume of ejected blood will be during the resulting systolic contraction (stroke volume).  This relationship holds up to a certain volume, but past that volume, there is a decline in contractility.  This decline in contractility is referred to as "falling of the<unk>  curve".  This is the mechanism by which the left ventricle initial dilates and increases contractility to adopt to chronic aortic insufficiency, but then eventually fails as it becomes to large and "falls off the<unk>  curve".
option_0: Frank-Starling law of the heart
option_1: Patent ductus arteriosus pathophysiology
option_2: Cardiac shunt
option_3: Patent ductus arteriosus causes
option_4: Patent ductus arteriosus classification
option_5: Left-to-right shunt
option_6: Ventricular septal defect pathophysiology
option_7: Atrial septal defect pathophysiology