text: <unk>  is most commonly autosomal dominant disorder caused by mutations involving three genes and rarely an autosomal recessive disorder involving<unk>  adaptor protein.  It is characterized by very high LDL cholesterol with associated atherosclerotic plaque deposition in arteries and a markedly increased risk of premature coronary artery disease.
option_0: Familial hypercholesterolemia
option_1: Familial combined hyperlipidemia
option_2: Primary hypertriglyceridemia
option_3: Hyperlipoproteinemia type 5
option_4: Hyperlipoproteinemia type II
option_5: Cretinism
option_6: Apolipoprotein B deficiency
option_7: Thiofanox