Optical coherence tomography findings in tamoxifen retinopathy.
To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifen retinopathy. Observational cases report. Two patients with tamoxifen retinopathy were imaged with fluorescein angiography and OCT 3. Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening. In both cases, OCT findings are not consistent with previous descriptions of tamoxifen retinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifen maculopathy may include a foveolar cystoid space different from macular edema.