Guanidinoethanesulfonic acid--inhibitor of GABA uptake in rat cortical synaptosomes.
Guanidinoethanesulfonic acid (GES) and taurine inhibit [3H]GABA uptake in rat cortical synaptosomes. The inhibitory effects of GES are more potent than taurine. These findings may explain the pharmacologic effects of GES in the CNS.