Effect of Schistosoma japonicum infection on serum testosterone levels in mice.
To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice. Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum. The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls. Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.