Cerebral stroke and myocardial lesions in stroke-prone SHR.
1) The histopathological abnormalities of the heart tended to be slightly severer in SHRSP with cerebrovascular lesions than those without cerebrovascular lesions. 2) However, SHRSP without cerebrovascular lesions also indicated abnormalities of VCG and histopathological findings. 3) Therefore, cerebral stroke may not directly affect or engender such myocardial lesions. 4) It is still remained to be solved whether the dysfunction of the heart with organic changes may partially contribute to the occurrence of cerebral stroke. 5) VCG appeared to correspond to the organic changes of the heart.