Study of some immunity parameters in patients receiving low-caloric diets.
The immunoregulatory effect of low-caloric diets on various components of the immune system was demonstrated. Serum content of TNF-alpha increased after the diet. Seasonal fluctuations in this parameter were observed in patients receiving these diets. A relationship between the increase in TNF-alpha level and body weight loss during low-caloric diet was detected. Presumably, transition to endogenous nutrition triggers not only catabolic hormones, but also cytokines with catabolic effects.