Age and malignant melanoma: comparison of variables in different age-groups.
Variables were compared in patients with clinical stage I superficial spreading melanoma who had been divided into three age-groups. The study included 736 consecutive patients who were prospectively entered into the data base of the Melanoma Cooperative Group of New York University Medical Center. Compared with the younger patients ( less than 40 years), older patients (greater than or equal to 60 years) had superficial spreading melanomas that were, on average, of greater thickness, level, and diameter. Younger patients were more likely than older patients to show evidence that their melanomas arose from preexisting nevocytic nevi. There was no difference in the 10-year survival between groups when melanomas were matched by thickness. Thus it is as important to perform periodic total cutaneous examinations in the elderly as it is in younger persons, and age alone should not determine management strategies.