[Intestine dysbacteriosis meaning in pathogenesis of chronic diarrhea of celiac disease and syndrome of the short small intestine].
To study the mechanisms of chronic diarrhea in patients with celiac disease and the syndrome of short small intestine. The study included 24 patients: 9 with celiac disease with malabsorption syndrome of II and III degree, 15 patients with the syndrome of short small intestine and 9 healthy volunteers. Study of microflora in the small and large intestine was performed by seeding serial dilutions of the contents of upper small intestine and feces, followed by qualitative and quantitative view of selected microorganisms. Value of free and conjugated bile acids were determined by electrophoresis followed by densitometry. 2/3 of the examined patients revealed bacterial colonization of the small intestine. Were inoculated staphylococci, E. coli, enterococci. Was found a significant change in the ratio of bile acids: a significant increase in free, damaging the mucous, and a decrease in conjugated involved in the digestion of lipids. Unabsorbed lipids were one of the causes of diarrhea in the examined groups of patients. Sequential antibiotic drugs and probiotic promoted the normalization of the stool, microflora of the small and large intestine.