[Attempt to objectify of coronary vessels course variability on the standard arteriograms by using original image processing algorithm].
The aim of paper: the analysis of standard angiograms of the left coronary artery was done in this paper in purpose of performing the uniform mathematical description of the coronary branches (both proximal and distal) course. The changes the coronary branches underwent depending the phase of cardiac cycle (diastole, isovolumic systole and tonic systole) were examined as well. The examined material consists of sequences of standard angiograms of the left coronary artery (LCA) obtained from 10 patients (5 male and 5 female) undergoing the standard diagnostic procedure in course of suspected unstable cardiac ischemia. The coronarograms were applied with digital angiography system INNOVA 2000 GE. The average age of the patients was 51 years. The method was based on using the original algorithm of image processing allowing automatic, in real-time, vessel edges detection and mathematical description of the vessels course. The software ImageJ, deriving from public domain of National Institutes of Health of USA was used for image analysis and for statistical analysis Statistica for Windows 5.5 version. The obtained results of examined dependences and describing them mathematically polynomial equations were presented on the diagrams. Among examined parameters the ferret diameter, area and perimeter of vessel outlines (both proximal and distal branches) were the most reliable. Their changes in relation to the phase of cardiac cycle were very close to the level of statistical significance. In conclusion the performed analysis allows to objectify description of coronary vessels course and variability. It also makes possible to identify the abnormal manners of vessels outlines that could be suspected of structural disorders even despite the absence of significant coronary stenosis.