Neurochemical differences between two strains of mice.
Microanalytic determinations of serotonin and norepinephrine were done on dissected portions of brain consisting of diencephalon, mesencephalon, and pons in two strains of mice, C57 bl/10 and BALB/c. The BALB/c strain had 1.34 microg of serotonin per gram of dissected brain, and the C57 bl/10 had 1.07 microg/g. This difference was statistically significant (P < 0.01). The levels of norepinephrine were not significantly different in the two strains (P > 0.25).