Using fractal analysis to characterize cerebral blood flow and immunohistopathology for ischemic stroke research.
This paper presents an application of fractal analysis to characterization of global cerebral blood flow and immunohistopathology for ischemic stroke research on animal experiments. A brain's vasculature has features of a branching tree and can be modeled as a fractal system. Fractal analysis can be then employed to assess cerebral blood flow and immuno-positives on a whole brain section. Fractal analysis on experimental data from three imaging modalities under ischemic and control status is presented in this paper. Statistic analysis and correlative study prove the effectiveness of fractal analysis. An analytical description of fractal parameters for experimental ischemic stroke has been achieved.