The present invention relates to compounds which neutralize axillary malodor.
Various approaches have been taken to the problem of axillary malodor. One approach has been the use of deodorants which may contain germicides and/or a fragrance. Germicides inhibit the reproduction of the bacteria which are believed to contribute to the production of axillary malodor. Fragrances are used to mask any odor produced. Another approach to the prevention of malodor is the use of antiperspirants. Antiperspirants inhibit bacteria and reduce the amount of sweat production thereby limiting the formation of substrate which gives rise to axillary malodor.
Certain metals and metal salts have been suggested for use in the control of odors. For example, Japanese Disclosure No. 83-222011 describes a cream for removing odor from the axilla which includes copper powder and perfume in a base of cosmetic cream. The disclosure postulates that the copper powder acts on the secretion of the odor, thereby suppressing generation of the malodor.
Another description of the use of metal salts against odors appears in French Patent No. 1,394,875. This French patent describes the use of water-soluble iron and copper compounds to reduce or eliminate body odors. Various salts and complexes of cupric copper and ferrous iron are mentioned, including sulfates, chlorides, acetates, gluconates, citrates, tartrates, salts of ethylenediamine tetraacetic acid sodium or potassium, and iron and copper chlorophyllins. Various iron and copper phosphates are also mentioned, especially for use as food additives. The most effective combinations are indicated to be those in which both metals are present in the ionizable and nonionizable forms. The only testing reported in the French patent was odor reduction of sewage sludge, and odor reduction in mice by measurement of the odor of the entire mouse, fecal odor and urine odor.
German Patent No. 1,083,503 describes the deodorizing action of metal complexes of 1,3-diketones. Listed metals include copper, nickel, cobalt, calcium, zirconium, zinc, tin, aluminum, cadmium, cerium, beryllium, magnesium, and mercury. Their use in various ways, including topical application to the axilla, is discussed. These compounds are theorized to function by interfering with the metabolism of the odor-producing microorganisms.
British Patent Application No. 1,581,586 describes a sanitary foot wear article which includes a composition comprising copper, silver, or a copper-silver alloy powder dispersed in and held by water-insoluble resin binder. The British patent application indicates a belief that the metal reacts with substances secreted by the foot to produce metal salts which act as astringents and also act to prevent the growth of microorganisms.
Despite the above, attempts have continued to find compositions which are effective against axillary malodor even after it has been formed.