This invention relates to therapeutic peptides.
A number of luteinizing hormone releasing hormone (LH-RH) analogs have been described which inhibit the release of LH-RH, a peptide hormone having the formula pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH.sub.2. For example, Coy et al. U.S. Pat. No. 4,431,635, hereby incorporated by reference, describes LH-RH analogs having the general formula X-R.sup.1 -R.sup.2 -R.sup.3 -Ser-Tyr-R.sup.4 -Leu-Arg-Pro-R.sup.5 -NH.sub.2, in which X can be Acetyl (AC); R.sup.1 and R.sup.4, independently, can be D-Trp or D-p-X-Phe, where X is a halogen or methyl group and (represents such throughout the rest of this application); R.sup.2 can be D-p-X-Phe; R.sup.3 can be D-Trp; and R.sup.10 can be Gly or D-Ala.