Inflammatory skin disorders acne, rosacea, and psoriasis afflict many millions of people. While not usually lethal, these conditions can cause physical discomfort and affect emotional well-being. There are currently a large number of different treatments for inflammatory skin disorders including corticosteroids, vitamin D analogs, coal tar, ultraviolet light, retinoids, methotrexate, cyclosporine, hydroxyurea, antibiotics, and biologic agents such as TNFalpha inhibitors. While these therapies have proven useful for many patients, many cause undesirable side-effects and none are ideal for every situation.