Prior art methods of treating proliferative disorders include systemic delivery of chemotherapy drugs. Dosage and frequency of these drugs is limited by their impact on healthy tissue and other side effects. Systemic delivery via the entire circulatory system of a patient delivers the drugs to all parts of the patient, rather than just a targeted tumor. For many proliferative disorders, chemotherapy concentration at the tumor is inadequate to completely eradicate the tumor. In disorders such as pancreatic cancer, prior art chemotherapy only extends life a few months. During these months, the quality of life of the patient is often low due to the chemotherapy side effects. Prior art includes a catheter with two inflatable balloons and with an infusion port between the balloons. As this device blocks blood flow, treatment time using the device is severely limited.
Prior art devices include drug infusion catheters that diffuse a drug radially in all directions from an infusion volume in the catheter. Such devices lack infusion directionality.