Her career culminated in her appointment as Director General – Health and Social Care – Welsh Government and NHS Wales CEO, a post she occupied for 8 years.
Uchafbwynt ei gyrfa oedd cael ei phenodi'n Gyfarwyddwr Cyffredinol – Iechyd a Gofal Cymdeithasol – Llywodraeth Cymru a Phrif Swyddog Gweithredol GIG Cymru.