do you need red alert 3 to play uprising
Command & Conquer: Red Alert 3 – Uprising Command & Conquer: Red Alert 3 â€“ Uprising is a 2009 real-time strategy video game developed by EA Los Angeles and published by Electronic Arts. It is a stand-alone expansion to Command & Conquer: Red Alert 3 released for Microsoft Windows and offered via digital distribution. It does not require Red Alert 3 to play. It features about 30 new maps for traditional skirmish with many of these taking place in new environments. It does not contain any multiplayer elements such as cooperative play, online play or network play.
Red blood cell The aging red blood cell undergoes changes in its plasma membrane, making it susceptible to selective recognition by macrophages and subsequent phagocytosis in the mononuclear phagocyte system (spleen, liver and lymph nodes), thus removing old and defective cells and continually purging the blood. This process is termed eryptosis, red blood cell programmed cell death.[47] This process normally occurs at the same rate of production by erythropoiesis, balancing the total circulating red blood cell count. Eryptosis is increased in a wide variety of diseases including sepsis, haemolytic uremic syndrome, malaria, sickle cell anemia, beta-thalassemia, glucose-6-phosphate dehydrogenase deficiency, phosphate depletion, iron deficiency and Wilson's disease. Eryptosis can be elicited by osmotic shock, oxidative stress, energy depletion as well as a wide variety of endogenous mediators and xenobiotics. Excessive eryptosis is observed in red blood cells lacking the cGMP-dependent protein kinase type I or the AMP-activated protein kinase AMPK. Inhibitors of eryptosis include erythropoietin, nitric oxide, catecholamines and high concentrations of urea.