how long does the effect of midazolam last
Midazolam Midazolam, marketed under the trade name Versed, among others, is a medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.[3] It works by inducing sleepiness, decreasing anxiety, and causing a loss of ability to create new memories.[3] It is also useful for the treatment of seizures.[5] Midazolam can be given by mouth, intravenously, or injection into a muscle, by spraying into the nose, or through the cheek.[3][5] When given intravenously, it typically begins working within five minutes; when injected into a muscle, it can take fifteen minutes to begin working.[3] Effects last for between one and six hours.[3]
Antihistamine Second-generation antihistamines cross the blood–brain barrier to a much lower degree than the first-generation antihistamines. Their main benefit is they primarily affect peripheral histamine receptors and therefore are less sedating. However, high doses can still induce drowsiness through acting on the central nervous system. Some second-generation antihistamines, notably cetirizine, can interact with CNS psychoactive drugs such as bupropion and benzodiazepines.[10]