when does pressure have the greatest effect on solubility
Partial pressure The form of the equilibrium constant shows that the concentration of a solute gas in a solution is directly proportional to the partial pressure of that gas above the solution. This statement is known as Henry's law and the equilibrium constant   k  {\displaystyle k}  is quite often referred to as the Henry's law constant.[8][9][10]
Mariana Trench At the bottom of the trench the water column above exerts a pressure of 1,086 bars (15,750 psi), more than 1,000 times the standard atmospheric pressure at sea level. At this pressure, the density of water is increased by 4.96%, so that 95.27 litres of water under the pressure of the Challenger Deep would contain the same mass as 100 litres at the surface. The temperature at the bottom is 1 to 4 °C (34 to 39 °F).[5]