what is the primary weakness of the des block cipher
Block cipher Due to a block cipher's characteristic as an invertible function, its output becomes distinguishable from a truly random output string over time due to the birthday attack. This property results in the cipher's security degrading quadratically, and needs to be taken into account when selecting a block size. There is a trade-off though as large block sizes can result in the algorithm becoming inefficient to operate.[28] Earlier block ciphers such as the DES have typically selected a 64-bit block size, while newer designs such as the AES support block sizes of 128 bits or more, with some ciphers supporting a range of different block sizes.[29]
First-degree atrioventricular block The most common causes of first-degree heart block are an AV nodal disease, enhanced vagal tone (for example in athletes), myocarditis, acute myocardial infarction (especially acute inferior MI), electrolyte disturbances and medication. The drugs that most commonly cause first-degree heart block are those that increase the refractory time of the AV node, thereby slowing AV conduction. These include calcium channel blockers, beta-blockers, cardiac glycosides, and anything that increases cholinergic activity such as cholinesterase inhibitors. Digitalis is a sodium/potassium ATPase inhibitor and also prolongs AV conduction.