how does staphylococcus aureus cause toxic shock syndrome
Toxic shock syndrome TSS is caused by bacteria of either the Streptococcus pyogenes or Staphylococcus aureus type.[1] Streptococcal toxic shock syndrome (STSS) is sometimes referred to as toxic shock-like syndrome (TSLS).[1] The underlying mechanism involves the production of superantigens during an invasive streptococcus infection or a localized staphylococcus infection.[1] Risk factors for the staphylococcal type include the use of very absorbent tampons and skin lesions in young children.[1] Diagnosis is typically based on symptoms.[1]
Allergy Common allergens include pollen and certain food.[10] Metals and other substances may also cause problems.[10] Food, insect stings, and medications are common causes of severe reactions.[3] Their development is due to both genetic and environmental factors.[3] The underlying mechanism involves immunoglobulin E antibodies (IgE), part of the body's immune system, binding to an allergen and then to a receptor on mast cells or basophils where it triggers the release of inflammatory chemicals such as histamine.[11] Diagnosis is typically based on a person's medical history.[4] Further testing of the skin or blood may be useful in certain cases.[4] Positive tests, however, may not mean there is a significant allergy to the substance in question.[12]