where does the name down syndrome come from
Down syndrome Down syndrome is one of the most common chromosome abnormalities in humans.[7] It occurs in about one per 1000 babies born each year.[1] In 2015, Down syndrome was present in 5.4 million individuals and resulted in 27,000 deaths down from 43,000 deaths in 1990.[9][10][18] It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866.[19] Some aspects of the condition were described earlier by Jean-Étienne Dominique Esquirol in 1838 and Édouard Séguin in 1844.[20] In 1957, the genetic cause of Down syndrome, an extra copy of chromosome 21, was discovered.[19]
Lewis (surname) One of the origins of the surname, in England and Wales, is from the Norman personal name Lowis, Lodovicus. This name is composed of the Germanic elements hlod and wig, meaning "fame" and "war". The name developed into the Old French Clovis, Clouis, Louis; as well as into the German Ludwig. The name Lowis spread to England through the Normans. Lewis has since become confused with other unrelated names. One such name is Llywelyn in Welsh which has been Anglicised into Lewis, with among the earliest examples being the Lewis family of Glamorgan in the 1540s.[1] Another is the Gaelic surname Mac Lughaidh, meaning "son of Lughaidh", which has also been Anglicised as Lewis. The surname Lewis is also an Anglicisation of several like-sounding Jewish surnames,[2] such as "Levy" or "Levi", and of the Arab form of the name "Elias".