when was penicillin first used on a large scale basis
Penicillin Penicillin was discovered in 1928 by Scottish scientist Alexander Fleming.[3] People began using it to treat infections in 1942.[4] There are several enhanced penicillin families which are effective against additional bacteria; these include the antistaphylococcal penicillins, aminopenicillins and the antipseudomonal penicillins. They are derived from Penicillium fungi.[5]
Roman concrete It is uncertain when Roman concrete was developed, but it was clearly in widespread and customary use from about 150 BC; some scholars believe it was developed a century before that.[3]