the foxp2 sequences of mice were most different from those of
FOXP2 The FOXP2 gene is highly conserved in mammals.[41] Human gene differs from non-human primates by the substitution of two amino acids, threonine to asparagine substitution at position 303 (T303N) and asparagine to serine substitution at position 325 (N325S).[32] In mice it differs from that of humans by three substitutions, and in zebra finch by seven amino acids.[17][42][43] One of the two amino acid difference between human and chimps also arose independently in carnivores and bats.[13][44] Similar FOXP2 proteins can be found in songbirds, fish, and reptiles such as alligators.[45][46]
Mickey Mouse In the spring of 1928, Disney asked Ub Iwerks to start drawing up new character ideas. Iwerks tried sketches of various animals, such as dogs and cats, but none of these appealed to Disney. A female cow and male horse were also rejected. They would later turn up as Clarabelle Cow and Horace Horsecollar. A male frog was also rejected. It would later show up in Iwerks' own Flip the Frog series.[5] Walt Disney got the inspiration for Mickey Mouse from a tame mouse at his desk at Laugh-O-Gram Studio in Kansas City, Missouri.[6] In 1925, Hugh Harman drew some sketches of mice around a photograph of Walt Disney. These inspired Ub Iwerks to create a new mouse character for Disney.[5] "Mortimer Mouse" had been Disney's original name for the character before his wife, Lillian, convinced him to change it, and ultimately Mickey Mouse came to be.[7][8] The actor Mickey Rooney claimed that, during his Mickey McGuire days, he met cartoonist Walt Disney at the Warner Brothers studio, and that Disney was inspired to name Mickey Mouse after him.[9] This claim, however, has been debunked by Disney historian Jim Korkis, since at the time of Mickey Mouse's development, Disney Studios had been located on Hyperion Avenue for several years, and Walt Disney never kept an office or other working space at Warner Brothers, having no professional relationship with Warner Brothers, as the Alice Comedies and Oswald cartoons were distributed by Universal.[10][11]