chronic granulomatous disease is due to an inherent deficiency of
Chronic granulomatous disease Chronic granulomatous disease (CGD) (also known as Bridgesâ€“Good syndrome, chronic granulomatous disorder, and Quie syndrome[1]) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.[2] This leads to the formation of granulomata in many organs.[3] CGD affects about 1 in 200,000 people in the United States, with about 20 new cases diagnosed each year.[4][5]
Paronychia Paronychia is a nail disease that is an often-tender bacterial or fungal infection of the hand or foot where the nail and skin meet at the side or the base of a finger or toenail. The infection can start suddenly (acute paronychia) or gradually (chronic paronychia).[1][2] Paronychia is commonly misapplied as a synonym for whitlow or felon. The term is from Greek: παρωνυχία from para, "around" and onukh-, "nail".