gentamicin belongs to which class of antibacterial agents
Gentamicin Gentamicin can cause inner ear problems and kidney problems.[1] The inner ear problems can include problems with balance and problems with hearing.[1] These problems may be permanent.[1] If used during pregnancy it can cause harm to the baby.[1] It appears to be safe for use during breastfeeding.[4] Gentamicin is a type of aminoglycoside.[1] It works by stopping the bacteria from making protein, which typically kills the bacteria.[1]
Biofilm Bacteria living in a biofilm usually have significantly different properties from free-floating bacteria of the same species, as the dense and protected environment of the film allows them to cooperate and interact in various ways.[34] One benefit of this environment is increased resistance to detergents and antibiotics, as the dense extracellular matrix and the outer layer of cells protect the interior of the community. In some cases antibiotic resistance can be increased a thousandfold.[35] Lateral gene transfer is often facilitated within bacterial and archaeal biofilms[36] and leads to a more stable biofilm structure.[37] Extracellular DNA is a major structural component of many different microbial biofilms.[38] Enzymatic degradation of extracellular DNA can weaken the biofilm structure and release microbial cells from the surface.