what is the denver ii developmental screening test
Denver Developmental Screening Test The DENVER II (1992) is a revision and update of the Denver Developmental Screening Test, DDST (1967).[6][7] Both were designed for use by the clinician, teacher, or other early childhood professional to monitor the development of infants and preschool-aged children. Doing so, enables the clinician to identify children whose development deviates significantly from that of other children warranting further investigation to determine if there exists a problem requiring treatment. The tests cover four general functions: personal social (such as smiling), fine motor adaptive (such as grasping and drawing), language (such as combining words), and gross motor (such as walking). Ages covered by the tests range from birth to six years. Since its publication the test has enjoyed widespread popularity as reflected by its use in many of this nation's medical schools.
Huntington's disease HD is typically inherited from a person's parents, although up to 10% of cases are due to a new mutation.[1] The disease is caused by an autosomal dominant mutation in either of an individual's two copies of a gene called Huntingtin.[4] This means a child of an affected person typically has a 50% chance of inheriting the disease.[4] The Huntingtin gene provides the genetic information for a protein that is also called "huntingtin".[1] Expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in an abnormal protein, which gradually damages cells in the brain, through mechanisms that are not fully understood.[4] Diagnosis is by genetic testing, which can be carried out at any time, regardless of whether or not symptoms are present.[5] This fact raises several ethical debates: the age at which an individual is considered mature enough to choose testing; whether parents have the right to have their children tested; and managing confidentiality and disclosure of test results.[2]