where does transcription begin or where is the transcription start site
Transcription (biology) Transcription begins with the binding of RNA polymerase, together with one or more general transcription factor, to a specific DNA sequence referred to as a "promoter" to form an RNA polymerase-promoter "closed complex". In the "closed complex" the promoter DNA is still fully double-stranded.[5]
Origin of replication DNA replication may proceed from this point bidirectionally or unidirectionally.[3]