when is a system said to be reproducible
Reproducibility Reproducibility is the ability to get the same research results or inferences, based on the raw data and computer programs provided by researchers. A related concept is replicability, meaning the ability to independently achieve non identical conclusions that are at least similar, when differences in sampling, research procedures and data analysis methods may exist.[1] Reproducibility and replicability together are among the main beliefs of ‘the scientific method’ - with the concrete expressions of the ideal/idea of such a method varying considerably across research disciplines and fields of study [2].
Plasmid In order for plasmids to replicate independently within a cell, they must possess a stretch of DNA that can act as an origin of replication. The self-replicating unit, in this case the plasmid, is called a replicon. A typical bacterial replicon may consist of a number of elements, such as the gene for plasmid-specific replication initiation protein (Rep), repeating units called iterons, DnaA boxes, and an adjacent AT-rich region.[7] Smaller plasmids make use of the host replicative enzymes to make copies of themselves, while larger plasmids may carry genes specific for the replication of those plasmids. A few types of plasmids can also insert into the host chromosome, and these integrative plasmids are sometimes referred to as episomes in prokaryotes.[8]