what are the signs and symptoms of hemolytic anemia
Hemolytic anemia Symptoms of hemolytic anemia are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones and pulmonary hypertension.[citation needed]
Coombs test The direct Coombs test is used clinically when immune-mediated hemolytic anemia (antibody-mediated destruction of RBCs) is suspected. A positive Coombs test indicates that an immune mechanism is attacking the patient's own RBCs. This mechanism could be autoimmunity, alloimmunity or a drug-induced immune-mediated mechanism.