what causes your anion gap to be high
High anion gap metabolic acidosis High anion gap metabolic acidosis is caused generally by acid produced by the body,. More rarely, high anion gap metabolic acidosis may be caused by ingesting methanol or overdosing on aspirin.[1][2] The Delta Ratio is a formula that can be used to assess elevated anion gap metabolic acidosis and to evaluate whether mixed acid base disorder (metabolic acidosis) is present.
Vitamin B12 deficiency anemia Vitamin B12 deficiency anemia, of which pernicious anemia is a type,[8] is a disease in which not enough red blood cells are present due to a lack of vitamin B12.[5] The most common initial symptom is feeling tired.[4] Other symptoms may include shortness of breath, pale skin, chest pain, numbness in the hands and feet, poor balance, a smooth red tongue, poor reflexes, depression and confusion.[4] Without treatment some of these problems may become permanent.[5]