where can glucose be found in the body
Glycogen Approximately 4Â grams of glucose are present in the blood of humans at all times;[2] in fasted individuals, blood glucose is maintained constant at this level at the expense of glycogen stores in the liver and skeletal muscle.[2] Glycogen stores in skeletal muscle serve as a form of energy storage for the muscle itself;[2] however, the breakdown of muscle glycogen impedes muscle glucose uptake, thereby increasing the amount of blood glucose available for use in other tissues.[2] Liver glycogen stores serve as a store of glucose for use throughout the body, particularly the central nervous system.[2] The human brain consumes approximately 60% of blood glucose in fasted, sedentary individuals.[2]
Insulin signal transduction pathway When carbohydrates are consumed, digested, and absorbed the pancreas senses the subsequent rise in blood glucose concentration and releases insulin to promote an uptake of glucose from the blood stream. When insulin binds to the insulin receptor, it leads to a cascade of cellular processes that promote the usage or, in some cases, the storage of glucose in the cell. The effects of insulin vary depending on the tissue involved, e.g., insulin is most important in the uptake of glucose by muscle and adipose tissue.