the analgesic effect of opioids is due to their
Opioid Opioids are substances that act on opioid receptors to produce morphine-like effects.[2] Medically they are primarily used for pain relief, including anesthesia.[3] Other medical uses include suppression of diarrhea, treating opioid use disorder, reversing opioid overdose, suppressing cough, and suppressing opioid induced constipation.[3] Extremely potent opioids such as carfentanil are only approved for veterinary use.[4] Opioids are also frequently used non-medically for their euphoric effects or to prevent withdrawal.[5]
Alka-Seltzer Alka-Seltzer is an effervescent antacid and pain reliever first marketed by the Dr. Miles Medicine Company of Elkhart, Indiana, United States. Alka-Seltzer contains three active ingredients: aspirin (acetylsalicylic acid) (ASA), sodium bicarbonate, and anhydrous citric acid.[1] The aspirin is a pain reliever and anti-inflammatory, the sodium bicarbonate is an antacid, and the citric acid reacts with the sodium bicarbonate and water to form effervescence.[2]