what is the denver ii developmental screening test
Denver Developmental Screening Test The DENVER II (1992) is a revision and update of the Denver Developmental Screening Test, DDST (1967).[6][7] Both were designed for use by the clinician, teacher, or other early childhood professional to monitor the development of infants and preschool-aged children. Doing so, enables the clinician to identify children whose development deviates significantly from that of other children warranting further investigation to determine if there exists a problem requiring treatment. The tests cover four general functions: personal social (such as smiling), fine motor adaptive (such as grasping and drawing), language (such as combining words), and gross motor (such as walking). Ages covered by the tests range from birth to six years. Since its publication the test has enjoyed widespread popularity as reflected by its use in many of this nation's medical schools.
Fragile X syndrome Fragile X syndrome is typically due to an expansion of the CGG triplet repeat within the Fragile X mental retardation 1 (FMR1) gene on the X chromosome.[1] This results in not enough fragile X mental retardation protein (FMRP), which is required for normal development of the connection between neurons.[1] Diagnosis is by genetic testing to determine the number of CGG repeats in the FMRI gene.[3] Normal is between 5 and 40 repeats, fragile X syndrome occurs with more than 200, and a premutation is said to be present when a middle number of repeats occur.[1] Testing for premutation carriers may allow for genetic counseling.[3]