when did the plain dealer begin their first publication
The Plain Dealer The newspaper was established in 1842, less than 50 years after Moses Cleaveland landed on the banks of the Cuyahoga River in The Flats, and is currently owned by Advance Publications (Newhouse Newspapers).[5] The Plain Dealer Publishing Company is under the direction of George Rodrigue (president). The paper employs over 700 people.
History of United States drug prohibition Around 1860: Efforts to regulate the sale of pharmaceuticals began, and laws were introduced on a state-to-state basis that created penalties for mislabeling drugs, adulterating them with undisclosed narcotics, and improper sale of those considered "poisons". Poison laws generally either required labels on the packaging indicating the harmful effects of the drugs or prohibited sale outside of licensed pharmacies and without a doctor's prescription. Prominent pharmaceutical societies at the time supported the listing of cannabis as a poison.[1]