where are hemidesmosomes commonly found and what is their function
Hemidesmosome Hemidesmosomes (HD) are very small stud- or rivet-like structures on the inner basal surface of keratinocytes in the epidermis of skin. They are similar in form to desmosomes when visualized by electron microscopy. While desmosomes link two cells together, hemidesmosomes attach one cell to the extracellular matrix. Instead of desmogleins, hemidesmosomes use integrins.[2] Hemidesmosomes are asymmetrical and are found in epithelial cells connecting the basal face of the cell to basal lamina.
Haematopoiesis Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types and tissues.[1] HSCs are self-renewing cells: when they differentiate, at least some of their daughter cells remain as HSCs, so the pool of stem cells is not depleted.This phenomenon is called asymmetric division.[4]  The other daughters of HSCs (myeloid and lymphoid progenitor cells) can follow any of the other differentiation pathways that lead to the production of one or more specific types of blood cell, but cannot renew themselves. The pool of progenitors is heterogeneous and can be divided into two groups; long-term self-renewing HSC and only transiently self-renewing HSC, also called short-terms.[5] This is one of the main vital processes in the body.