early cultures were present in the americas before the arrival of
Pre-Columbian era While the phrase "pre-Columbian era" literally refers only to the time preceding Christopher Columbus's voyages of 1492, in practice the phrase is usually used to denote the entire history of indigenous Americas cultures until those cultures were exterminated, diminished, or extensively altered by Europeans, even if this happened decades or centuries after Columbus's first landing. For this reason the alternative terms of Precontact Americas, Pre-Colonial Americas or Prehistoric Americas are also in use. In areas of Latin America the term usually used is Pre-Hispanic.
Spanish colonization of the Americas Beginning with the 1492 arrival of Christopher Columbus in the Caribbean and continuing control of vast territory for over three centuries, the Spanish Empire would expand across the Caribbean Islands, half of South America, most of Central America and much of North America (including present day Mexico, Florida and the Southwestern and Pacific Coastal regions of the United States). It is estimated that during the colonial period (1492–1832), a total of 1.86 million Spaniards settled in the Americas and a further 3.5 million immigrated during the post-colonial era (1850–1950); the estimate is 240,000 in the 16th century; and most during the 18th century as immigration was encouraged by the new Bourbon Dynasty.