increase in the size of an organ by enlarging of cells
Hypertrophy Hypertrophy (/haɪˈpɜːrtrəfi/, from Greek ὑπέρ "excess" + τροφή "nourishment") is the increase in the volume of an organ or tissue due to the enlargement of its component cells.[1] It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number.[2] Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally-induced proliferation and enlargement of the cells of the uterus during pregnancy.
Renin The enzyme renin is secreted by pericytes (mural cells) (1) in vicinity of the afferent arterioles and similar microvessels of the kidney from specialized cells of the juxtaglomerular apparatusâ€”the juxtaglomerular cells, in response to three stimuli: