a deficiency of thiamin causes a disorder called
Thiamine deficiency Thiamine deficiency, also known as beriberi, is a condition that occurs due to not enough thiamine (vitamin B1).[1] There are two main types: wet beriberi, and dry beriberi.[1] Wet beriberi results in a fast heart rate, shortness of breath, and leg swelling.[1] Dry beriberi results in numbness of the hands and feet, confusion, trouble moving the legs, and pain.[1] A form with loss of appetite and constipation may also occur.[3]
Phenylketonuria Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine.[3] Untreated PKU can lead to intellectual disability, seizures, behavioral problems, and mental disorders.[1] It may also result in a musty smell and lighter skin.[1] Babies born to mothers who have poorly treated PKU may have heart problems, a small head, and low birth weight.[1]