bupernorphine (buprenex® subutex® suboxone®) is used to treat which substance use disorder
Buprenorphine Buprenorphine, sold under the brand name Subutex, among others, is an opioid used to treat opioid addiction, acute pain, and chronic pain.[3] It can be used under the tongue, by injection, as a skin patch, or as an implant.[3][4] For opioid addiction it is typically only started when withdrawal symptoms have begun and for the first two days of treatment under direct observation of a health care provider.[3] For longer term treatment of addiction a combination formulation of buprenorphine/naloxone is recommended to prevent misuse by injection.[3] Maximum pain relief is generally within an hour with effects up to 24 hours.[3]
Sodium thiopental Sodium thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia. Its use has been largely replaced with that of propofol, but retains popularity as an induction agent for rapid sequence intubation and in obstetrics.[citation needed] Following intravenous injection, the drug rapidly reaches the brain and causes unconsciousness within 30–45 seconds. At one minute, the drug attains a peak concentration of about 60% of the total dose in the brain. Thereafter, the drug distributes to the rest of the body, and in about 5–10 minutes the concentration is low enough in the brain that consciousness returns.[citation needed]