an antiviral drug that is also used in the treatment of parkinson's disease is
Rimantadine Rimantadine, like its antiviral cousin amantadine, possesses some NMDA antagonistic properties and is used as an antiparkinsonic drug (i.e., in the treatment of Parkinson's disease). However, in general, neither rimantadine nor amantadine is a preferred agent for this therapy and would be reserved for cases of the disease that are less responsive to front-line treatments.
Substantia nigra The substantia nigra is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. Substantia nigra is Latin for "black substance", reflecting the fact that parts of the substantia nigra appear darker than neighboring areas due to high levels of neuromelanin in dopaminergic neurons.[1] It was discovered in 1784 by Félix Vicq-d'Azyr,[2] and Samuel Thomas von Sömmerring alluded to this structure in 1791.[3] Parkinson's disease is characterized by the death of dopaminergic neurons in the substantia nigra pars compacta.[4]