when the herpesvirus is latent it resides in which area
Virus latency One example is herpes virus family, Herpesviridae, all of which establish latent infection. Herpes virus include chicken-pox virus and herpes simplex viruses (HSV-1, HSV-2), all of which establish episomal latency in neurons and leave linear genetic material floating in the cytoplasm.[3] The Gammaherpesvirinae subfamily is associated with episomal latency established in cells of the immune system, such as B-cells in the case of Epstein-Barr virus.[3][4] Epstein-Barr virus lytic reactivation (which can be due to chemotherapy or radiation) can result in genome instability and cancer.[5] In the case of herpes simplex (HSV), the virus has been shown to fuse with DNA in neurons, such as nerve ganglia[6] or brain cells[citation needed], and HSV reactivates upon even minor chromatin loosening with stress,[7] although the chromatin compacts (becomes latent) upon oxygen and nutrient deprivation.[8]
Viral entry Prior to entry, a virus must attach to a host cell. Attachment is achieved when specific proteins on the viral capsid or viral envelope bind to specific proteins called to receptor proteins receptors on the cell membrane of the target cell. A virus must now enter the cell, which is covered by a phospholipid bilayer, a cell's natural barrier to the outside world. The process by which this barrier is breached depends upon the virus. Types of entry are: