chronic granulomatous disease is due to an inherent deficiency of
Chronic granulomatous disease Chronic granulomatous disease (CGD) (also known as Bridgesâ€“Good syndrome, chronic granulomatous disorder, and Quie syndrome[1]) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.[2] This leads to the formation of granulomata in many organs.[3] CGD affects about 1 in 200,000 people in the United States, with about 20 new cases diagnosed each year.[4][5]
Leukonychia Leukonychia (or leuconychia), also known as white nails or milk spots,[1] is a medical term for white discolouration appearing on nails.[2]:658â€“9 It is derived from the Greek words leuko ("white") and nychia ("nails"). The most common cause is injury to the base of the nail (the matrix) where the nail is formed.