who contributed to the discovery of dna structure
Erwin Chargaff Erwin Chargaff (11 August 1905 â€“ 20 June 2002) was an Austro-Hungarian biochemist that immigrated to the United States during the Nazi era and was a professor of biochemistry at Columbia University medical school.[1] Through careful experimentation, Chargaff discovered two rules that helped lead to the discovery of the double helix structure of DNA.
Taq polymerase In the early 1980s, Kary Mullis was working at Cetus Corporation on the application of synthetic DNAs to biotechnology. He was familiar with the use of DNA oligonucleotides as probes for binding to target DNA strands, as well as their use as primers for DNA sequencing and cDNA synthesis. In 1983, he began using two primers, one to hybridize to each strand of a target DNA, and adding DNA polymerase to the reaction. This led to exponential DNA replication,[7] greatly amplifying the amounts of DNA between the primers.[3]