when was penicillin first used on a large scale basis
Penicillin Penicillin was discovered in 1928 by Scottish scientist Alexander Fleming.[3] People began using it to treat infections in 1942.[4] There are several enhanced penicillin families which are effective against additional bacteria; these include the antistaphylococcal penicillins, aminopenicillins and the antipseudomonal penicillins. They are derived from Penicillium fungi.[5]
Fountain pen Progress in developing a reliable pen was slow until the mid-19th century because of an imperfect understanding of the role that air pressure plays in the operation of pens. Furthermore, most inks were highly corrosive and full of sedimentary inclusions. The Romanian inventor Petrache Poenaru received a French patent on May 25, 1827, for the invention of the first fountain pen with a barrel made from a large swan quill.[8]