when does izzy get cancer in greys anatomy
Izzie Stevens Heigl garnered critical acclaim for her performance as Izzie and received numerous awards and nominations for her role, winning the "Outstanding Supporting Actress In A Drama Series" at the 2007 Emmy Awards. She was critical of the character's development during the show's fourth season, particularly her romance with George. She declined to put herself forward for the 2008 Emmy Awards, citing insufficient material in the role. After speculation that Izzie would be killed off in the fifth season, the character was diagnosed with Stage 4 metastatic melanoma. She married Alex in the series' one-hundredth episode, and afterwards, her tumor was successfully removed. Izzie made her final appearance in the sixth season, leaving Seattle after Alex refused to resume their marriage. Heigl requested to be released from her contract 18Â months early, in order to spend more time with her family. In January 2012, Heigl reported that she would like to return to Grey's Anatomy to give closure to her character, however, Rhimes confirmed that there were no plans to have the character return at that time and has since stated that she has no plans to ever re-approach Izzie's storyline again.
Alex Karev Alex is fired by Dr. Lebackes when Maggie Pierce accidentally reveals to him that Karev was thinking about leaving the job. Webber recommended Bailey to fill Yang's board seat after she left, so Bailey and Alex fight over the chair. They both make presentations to the board and eventually Bailey wins, with a unanimous vote in her favor. He is hired back as an attending Peds surgeon and takes over full-time as Arizona pursues a fellowship with Dr. Herman. Alex continues to date Jo and his friendship with Meredith grows stronger than ever, with him taking on the role of her new person. When Derek dies and Meredith runs away, Alex is upset by her leaving without telling him where she went and calls her everyday. Eventually she calls him, tells him she is okay, and to stop calling. When she goes into labor and gives birth to Ellis Shepherd, Alex goes to see her since he is her emergency contact. He brings Meredith and her kids back to her house. She asks to move back in with him in her old house. Alex sells Meredith back the house and he and Jo rent a loft.