몇몇 연구는 PS가 야생형 EGFR 환자에서 EGFRTKI에 대한 반응 예측 인자였으며, 여성 성은 첨단 비소세포 폐암 환자들의 게피티니브 치료의 독립적인 좋은 예측 변수였다고 보고했다.
Several studies reported that PS was predictive factor for response to EGFR TKI in patients with wild-type EGFR and female sex was independent good predictors of gefitinib treatment in patients with advanced non-small cell lung cancer.