오응정은 1574년 무과에 급제하였고, 임진왜란 당시 선조(재위 1567-1608)가 의주로 피난갈 때 호종하였다.
O Eung-jeong passed the state examination in 1574. With the outbreak of the Japanese invasions in 1592, he escorted King Seonjo (r. 1567-1608) and the royal family members to refuge near the northern border of the Korean Peninsula.