A549 상피세포와 유사하게, TGF-1은 CCD-11Lu 섬유아세포에서 p-Smad2/3 식을 크게 증가시켰으며, ATRA의 투여로 이 효과를 완전히 억제했다.
Similar to the A549 epithelial cells, TGF-1 significantly increased p-Smad2/3 expression in CCD-11Lu fibroblasts, and this effect was completely suppressed by administration of the ATRA.