본 발명은 하기의 화학식(I)의 화합물; 및 이들의 산 및 염기와의 부가염에 관한 것이며:화학식(I) - 동일하거나 다른, A1 및 A2는 H, (C1-C6)알킬((C1-C6)alkyl), (C1-C6)플루오로알킬((C1-C6)fluoroalkyl), (C2-C6)알케닐((C2-C6)alkenyl), (C2-C6)알키닐((C2-C6)alkynyl), (C1-C6)알킬-ORa((C1-C6)alkyl-ORa), (C1-C6)알킬-SRa((C1-C6)alkyl-SRa), (C1-C6)알킬-NRaRb((C1-C6)alkyl-NRaRb), ORa, SRa, NRaRb, 또는 CORa이며, - A3는 H, OH 이거나 A4와 카르보닐기(carbonyl)를 형성하고; - A4는 H, OH 이거나 상기 A3와 카르보닐기(carbonyl)를 형성하며; - A5는 CRaRbOH, F, OH 이거나 X가 CH인 경우에 X와 이중 결합을 형성하고; - A6는 H 또는 F이며; - X는 CH2, CHF, CF2, CHOH, O, S, NRa 또는 단일 결합이거나, X는 A5가 X와 이중 결합을 형성하는 경우 CH이고; - Y는 P(O)(ORa)(ORb) 또는 P(O)(ORa)(NRaRb)이며; - V는 O 또는 S이고; - A7는 H, (C1-C6)알킬((C1-C6)alkyl), (C1-C6)플루오로알킬((C1-C6)fluoroalkyl), (C2-C6)알케닐((C2-C6)alkenyl), (C2-C6)알키닐((C2-C6)alkynyl) 또는 (C1-C6)알킬-ORa((C1-C6)alkyl-ORa)이며; - A8는 OH 또는 H이고; - 동일하거나 다른, Ra 및 Rb는 H, (C1-C6)알킬((C1-C6)alkyl), (C1-C6)플루오로알킬((C1-C6)fluoroalkyl), (C1-C6)알킬-OH((C1-C6)alkyl-OH) 및 (C1-C6)알킬-O-(C1-C6)알킬((C1-C6)alkyl-O-(C1-C6)alkyl)으로 이루어진 그룹으로부터 선택되며; 항균성 예방 및 치료에서 이들이 제조되고 이용되며, 항균제(antibacterials) 또는 항바이러스제(antivirulence agents) 또는 선천적 면역을 강화시키는 약물과 결합하여 또는 단독으로 이용된다. 
The invention relates to compounds of formulae (Ia), (Ib) or (Ic) wherein, -A1 and A2, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, (C1-C6) alkyl-ORa, (C1-C6) alkyl-SRa, (C1-C6) alkyl-NRaRb, ORa, SRa, NRaRb, or CORa; - A3 is H, OH or form a carbonyl with A4; -A4 is H, OH or form a carbonyl with A3; -A5 is H, CRaRbOH, F, OH or forms a double bond with X in the case where X is CH; -A6 is H or F; -X is CH2, CHF, CF2, CHOH, O, S, NRa or a simple bond, or X is CH in the case where A5 forms with X a double bond; -Y is P(O) (ORa) (ORb) or P (O) (ORa) (NRaRb); -V is O or S; -A7 is H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C1-C6) alkyl-ORa; -A8 is OH or H, -Ra and Rb, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C1-C6) alkyl-OH or (C1-C6) alkyl-O-(C1- C6) alkyl; and their addition salts thereof with acids and bases, their preparation and their use in the antibacterial prevention and therapy, used alone or in association with antibacterials, antivirulence agents or drugs reinforcing the host innate immunity.