Bax 발현이 증가하고 Bcl-2 발현이 감소되는 상태에서는 세포 자연사가 유발되고, Bax 발현이 억제되고 Bcl-2 발현이 증가하는 상태에서는 세포 자연사가 억제된다고 하였다.
It was said that natural cellular death had been induced when Bax expression was increased and Bcl-2 expression was reduced, and natural cell death was suppressed when Bax expression was suppressed and Bcl-2 expression was increased.