难治性Tourette综合征（intractableTourettesyndrome）的诊断标准：①符合ICD-10中TS的诊断标准，排除风湿性舞蹈病、肝豆状核变性、习惯性痉挛和癫痫；②YGTSS得分≥50；③经氟哌啶醇或和硫必利足量治疗1年以上无效。
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