【病因及遗传学】AS是一种以血尿及进行性肾脏损害为主要表现的肾小球基底膜（basementmembrane，BM）病，可伴有眼、耳等肾外表现。
O O O O O O O O B-dis I-dis O O O O B-sym I-sym O B-dis I-dis I-dis I-dis I-dis I-dis I-dis O O O O O O B-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis O O O O B-sym I-sym I-sym I-sym I-sym I-sym I-sym I-sym O