2.达那唑有抗孕激素和雌激素作用，其作用机制是反馈抑制下丘脑垂体促性腺激素分泌，使体内雌激素水平下降有时见声音粗、毛发增多以及出现粉刺甲羟孕酮（又称安宫黄体酮）由于副作用较大，已不再用于治疗性早熟。
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