根据发病年龄，病变范围和临床表现，将此类疾病分为三种亚型，包括勒-雪综合征（Letterer-Siwesyndrome），韩-薛-柯综合征（Hand-Schuller-Christiansyndrome）和骨嗜酸细胞性肉芽肿。
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