当胃内容物反流至食管导致组织损伤而引起症状则为病理性反流，随之出现的一系列疾病症状，统称为胃食管反流病（gastroesophagealrefluxdisease，GERD）。
O B-bod O O O O O O O O O O O O O O O O O O O O O B-dis I-dis I-dis I-dis I-dis O O O O O O O O O O O O O O O O O B-dis I-dis I-dis I-dis I-dis I-dis O B-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis O B-dis I-dis I-dis I-dis O O