表17-4以抗体缺陷为主的免疫缺陷病续表注：XLA：X连锁无丙种球蛋白血症；CVID：常见变异型免疫缺陷病；Igk：免疫球蛋白κ链1.X连锁无丙种球蛋白血症（Xlinkedagammaglobulinaemia，XLA）本病又称Bruton病，因定位于Xq12.3-3上的Bruton酪氨酸激酶（Btk）基因缺失或突变，使B细胞发育受阻于原B细胞，极少成熟B细胞（CD20+</sup>，CD19+</sup>，SIg+</sup>B细胞少于2%）。
O O O O O O B-dis I-dis I-dis I-dis O O O B-dis I-dis I-dis I-dis I-dis O O O O B-dis I-dis I-dis O B-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis O B-dis I-dis I-dis I-dis O B-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis O B-dis I-dis I-dis O B-dis I-dis I-dis I-dis I-dis I-dis I-dis O O B-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis O B-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis I-dis O B-dis I-dis I-dis O O O O O B-dis I-dis I-dis I-dis I-dis I-dis I-dis O O O O O B-bod I-bod I-bod I-bod I-bod I-bod I-bod I-bod O O B-bod I-bod I-bod I-bod I-bod I-bod I-bod I-bod I-bod I-bod I-bod O B-bod I-bod I-bod O O O O O O O O O O B-bod I-bod I-bod O O O O O B-bod I-bod I-bod I-bod O O O B-bod I-bod I-bod I-bod I-bod O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O