其中日本人和中国人HLA-DR2位点频率增高，西欧血统白人HLA-DR2和/或DR3位点频率增高，我国南方汉人SLE发病与DRB1*0301及DQB1*0608有关，美国黑人与DRB1*1503、DQA1*0102和DQB1*0602有关。
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